Momose Isao 百瀬功

… Alternative Names

MOMOSE Isao 百瀬功

百瀬功モモセイサオ

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Researcher Number	10270547
Other IDs
Affiliation (Current)	2025: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 支所長
Affiliation (based on the past Project Information) *help	2024: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 支所長 2015 – 2023: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 主席研究員 2017: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 主席研究員 2014: 公益財団法人微生物化学研究会, 微生物化学研究所・沼津支所, 主席研究員 2011 – 2013: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 主席研究員 2005: (財)微生物化学研究会, 微生物化学研究センター沼津創薬医科学研究所, ユニット長 2003 – 2004: (財)微生物化学研究会, 微生物化学研究センター・沼津創薬医科学研究所, ユニット長
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Biomolecular chemistry / Living organism molecular science / Biological pharmacy Except Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Urology
Keywords	Principal Investigator プロテアソーム / エラジタンニン / 骨肉腫 / 乳酸デヒドロゲナーゼ阻害剤 / キヌレニン産生阻害剤 / 複合的がん免疫療法 / 免疫チェックポイント阻害剤 / 乳酸デヒドロゲナーゼ / 免疫チェックポイント / 乳酸 … More / キヌレニン / 乳酸デキヒドロゲナーゼ / インドールアミン2,3-ジオキシゲナーゼ / がん代謝 / 天然物化合物 / レドックス制御 / 低栄養 / がん微小環境 / パピラシリン酸 / ペニシリン酸 / 栄養欠乏 / グルタチオン / 二次代謝産物 / 微生物 / 代謝 / がん / 経口投与 / 経口剤 / プロテアソーム阻害剤 / インビボイメージング / 薬剤耐性 / チロペプチン / プロテアソーム阻害物質 … More Except Principal Investigator リン脂質リモデリング / 抗がん剤 / LPCAT1 / cーmyc / c-myc / 乳がん / c-Myc / 合成致死 / アンドロゲンレセプター / 前立腺がん Less

Drug discovery of new ellagitannins as next-generation therapeutic agents for osteosarcomaPrincipal Investigator
- Principal Investigator
  
  百瀬功
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Microbial Chemistry Research Foundation
細胞膜リン脂質リモデリングを標的とした新規抗がん剤の創出
- Principal Investigator
  
  山崎洋子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Microbial Chemistry Research Foundation
Development of comprehensive cancer immunotherapy using metabolism inhibitorsPrincipal Investigator
- Principal Investigator
  
  Momose Isao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Microbial Chemistry Research Foundation
Development of new anticancer drugs that exhibit synthetic lethal effects with c-myc on breast cancer
- Principal Investigator
  
  YAMAZAKI Yohko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Microbial Chemistry Research Foundation
Development of drugs targeting cancer metabolismPrincipal Investigator
- Principal Investigator
  
  MOMOSE Isao
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Microbial Chemistry Research Foundation
Elucidation of androgen-dependent growth inhibition mechanism in prostate cancer of novel small molecule compound APA
- Principal Investigator
  
  YAMAZAKI Yohko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Microbial Chemistry Research Foundation
Development of orally active proteasome inhibitors using in vivo imaging.Principal Investigator
- Principal Investigator
  
  MOMOSE Isao
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Microbial Chemistry Research Foundation
プロテアリーム阻害物質チロペプチン類縁体による細胞内蛋白質の変動と生物活性Principal Investigator
- Principal Investigator
  
  百瀬功
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Microbial Chemistry Research Foundation

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2005 Other

All Journal Article Presentation

[Journal Article] Deoxynortryptoquivaline: A unique antiprostate cancer agent2023
- Author(s)
  Yamazaki Y, Kawada M, Momose I.
- Journal Title
  
  Oncol Res.
  
  Volume: 31 Issue: 6 Pages: 845-853
- DOI
  10.32604/or.2023.030266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06675
[Journal Article] Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer2022
- Author(s)
  Kubota Yuji、Fujioka Yuko、Patil Ashwini、Takagi Yusuke、Matsubara Daisuke、Iijima Masatomi、Momose Isao、Naka Ryosuke、Nakai Kenta、Noda Nobuo N.、Takekawa Mutsuhiro
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 4063-4063
- DOI
  10.1038/s41467-022-31690-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02692, KAKENHI-PROJECT-20K07124, KAKENHI-INTERNATIONAL-16K21739
[Journal Article] Boronic Acid as a Promising Class of Chemical Entity for Development of Clinical Medicine for Targeted Therapy of Cancer2022
- Author(s)
  渡辺匠, 百瀬功
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 142 Issue: 2 Pages: 145-153
- DOI
  10.1248/yakushi.21-00173-3
- NAID
  130008149679
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2022-02-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07124
[Journal Article] Quinofuracins F - I, new quinofuracin derivatives produced by Staphylotrichum boninense PF14442021
- Author(s)
  Tatsuda, D., Amemiya, M., Sawa, R. Momose, I., Kawada, M.
- Journal Title
  
  J. Antibiot
  
  Volume: 74 Issue: 10 Pages: 758-762
- DOI
  10.1038/s41429-021-00452-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07311, KAKENHI-PROJECT-20K07124
[Journal Article] Potential Anticancer Activity of Auranofin2021
- Author(s)
  百瀬功, 小野寺威文, 川田学
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 141 Issue: 3 Pages: 315-321
- DOI
  10.1248/yakushi.20-00179-2
- NAID
  130007992970
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2021-03-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07124
[Journal Article] Androprostamine A: a unique antiprostate cancer agent2021
- Author(s)
  Yamazaki Y, Abe H, Sakashita C, Ohba SI, Watanabe T, Momose I, Kawada M.
- Journal Title
  
  J Antibiot
  
  Volume: 74 Issue: 10 Pages: 717-725
- DOI
  10.1038/s41429-021-00449-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07157, KAKENHI-PROJECT-20K07124
[Journal Article] Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition.2020
- Author(s)
  T Onodera, I Momose, H Adachi, Y Yamazaki, R Sawa, SI Ohba, M Kawada.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 49 Pages: 16678-16690
- DOI
  10.1074/jbc.ra120.013893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07157, KAKENHI-PROJECT-20K07124
[Journal Article] Leucinostatin Y: A Peptaibiotic Produced by the Entomoparasitic Fungus Purpureocillium lilacinum 40-H-28.2019
- Author(s)
  I. Momose, T. Onodera, H. Doi, H. Adachi, M. Iijima, Y. Yamazaki, R. Sawa, Y. Kubota, M. Igarashi, M. Kawada
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 印刷中 Issue: 5 Pages: 1120-1127
- DOI
  10.1021/acs.jnatprod.8b00839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-19K07157, KAKENHI-PROJECT-17K15000
[Journal Article] Potential Anticancer Activity of Auranofin2019
- Author(s)
  T. Onodera, I. Momose, M. Kawada
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 3 Pages: 186-191
- DOI
  10.1248/cpb.c18-00767
- NAID
  130007607281
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-17K15000
[Journal Article] A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2.2018
- Author(s)
  M. Iijima, Yuji Kubota, R. Sawa, Yumiko Kubota, M. Hatano, M. Igarashi, M. Kawada, I. Momose, M. Takekawa, M. Shibasaki.
- Journal Title
  
  J. Antibiot.
  
  Volume: 71 Issue: 1 Pages: 135-138
- DOI
  10.1038/ja.2017.100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-15H04703, KAKENHI-PROJECT-16K15212, KAKENHI-PROJECT-17K08650
[Journal Article] Tyropeptins, proteasome inhibitors produced by Kitasatospora sp. MK993-dF2.2017
- Author(s)
  I. Momose, T. Watanabe
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 5 Pages: 542-550
- DOI
  10.1038/ja.2017.9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01811
[Journal Article] Acremopeptin, a new peptaibol from Acremonium sp. PF1450.2017
- Author(s)
  M. Iijima, M. Amemiya, R. Sawa, Y. Kubota, T. Kunisada, I. Momose, M. Kawada, M. Shibasaki
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 6 Pages: 791-794
- DOI
  10.1038/ja.2017.15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K06888
[Journal Article] Synthesis of Androprostamine A and Resormycin2016
- Author(s)
  H. Abe, Y. Yamazaki, C. Sakashita, I. Momose, T. Watanabe, M. Shibasaki
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 7 Pages: 982-987
- DOI
  10.1248/cpb.c16-00207
- NAID
  130005160028
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K10615
[Journal Article] Coccoquinones A and B, new anthraquinone derivatives produced by Staphylotrichum coccosporum PF1460.2016
- Author(s)
  Tatsuda D, Amemiya M, Sawa R, Sumiyoshi K, Watanabe T, Momose I, Kawada M, Nomoto A, Shibasaki M.
- Journal Title
  
  J Antibiot
  
  Volume: 69 Issue: 3 Pages: 176-178
- DOI
  10.1038/ja.2015.102
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01811
[Journal Article] Biological activities of unique isoflavones prepared from Apios americana Medik.2016
- Author(s)
  Kaneta H, Koda M, Saito S, Imoto M, Kawada M, Yamazaki Y, Momose I, Shindo K.
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 80 Issue: 4 Pages: 774-778
- DOI
  10.1080/09168451.2015.1127132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K10615
[Journal Article] The therapeutic potential of microbial proteasome inhibitors.2016
- Author(s)
  I. Momose, M. Kawada
- Journal Title
  
  Int. Immunopharmacol.
  
  Volume: 37 Pages: 23-30
- DOI
  10.1016/j.intimp.2015.11.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K06888
[Journal Article] Androprostamines A and B, the new anti-prostate cancer agents produced by Streptomyces sp. MK932-CF8.2015
- Author(s)
  Yamazaki Y, Someno T, Igarashi M, Kinoshita N, Hatano M, Kawada M, Momose I, Nomoto A.
- Journal Title
  
  J. Antibiot.
  
  Volume: 68 Issue: 4 Pages: 279-285
- DOI
  10.1038/ja.2014.135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23510270, KAKENHI-PROJECT-24592417, KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K06888
[Journal Article] Quinofuracins A-E, produced by the fungus Staphylotrichum boninense PF1444, show p53-dependent growth suppression.2015
- Author(s)
  Tatsuda D, Momose I, Someno T, Sawa R, Kubota Y, Iijima M, Kunisada T, Watanabe T, Shibasaki M, Nomoto A.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 78 Issue: 2 Pages: 188-195
- DOI
  10.1021/np500581m
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23510270, KAKENHI-PROJECT-15K01811
[Journal Article] Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors.2014
- Author(s)
  Momose I, Abe H, Watanabe T, Ohba S, Yamazaki K, Dan S, Yamori T, Masuda T, Nomoto A.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 12 Pages: 1609-1615
- DOI
  10.1111/cas.12542
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23510270
[Journal Article] In vivo imaging of proteasome inhibition using a proteasome-sensitive fluorescent reporter2012
- Author(s)
  Isao Momose, Daisuke Tatsuda, Shun-ichi Ohba, Tohru Masuda, Daishiro Ikeda, Akio Nomoto
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 9 Pages: 1730-1736
- DOI
  10.1111/j.1349-7006.2012.02352.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790217, KAKENHI-PROJECT-23390113, KAKENHI-PROJECT-23510270
[Journal Article] Decalpenic acid induces early osteoblastic markers in pluripotent mesenchymal cells via activation of retinoic acid receptor gamma.2012
- Author(s)
  Sakamoto, S., Kojima, F., Momose, I., Kawada, M., Adachi, H., and Nishimura, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 422 Issue: 4 Pages: 751-757
- DOI
  10.1016/j.bbrc.2012.05.075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501321, KAKENHI-PROJECT-23510270, KAKENHI-PROJECT-23790452, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23112522, KAKENHI-PUBLICLY-24102532
[Journal Article] Structure-Based Design of Derivatives of Tyropeptin A as the Potent and Selective Inhibitors of Mammalian 20S Proteasome2005
- Author(s)
  Momose Isao et al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 15・7
  
  Pages: 1867-1871
- Data Source
  KAKENHI-PROJECT-15790059
[Journal Article] Synthesis and activity of tyropeptin A derivatives as potent and selective inhibitors of mammalian 20S proteasome.2005
- Author(s)
  Momose Isao et al.
- Journal Title
  
  Biosci.Biotechnol. Biochem 69・10
  
  Pages: 1733-1742
- NAID
  130000030210
- Data Source
  KAKENHI-PROJECT-15790059
[Presentation] 神経膠芽腫由来細胞におけるErtredinによるEGFRvIIIタンパクの減少とスフェロイド形成抑制2022
- Author(s)
  渥美園子、野坂千里、川田学、小野寺威文、山崎洋子、大石智一、百瀬功、澁谷正史、内藤幹彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] Synthetic lethal approach that targets c-MYC-driven cancers2022
- Author(s)
  Y. Yamazaki, SI. Ohba, T Onodera, M. Kawada and I. Momose
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] c-Mycと合成致死作用を示す低分子化合物の探索研究2022
- Author(s)
  山崎洋子、大庭俊一、小野寺威文、川田学、百瀬功
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] 低栄養環境で高発現しているがん特異的代謝遺伝子の機能解明2022
- Author(s)
  小野寺威文、坂本修一、大庭俊一、百瀬功、川田学
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] Human pancreatic cancer cells are vulnerable to inhibition of redox system under nutrient deprivation2022
- Author(s)
  I. Momose, T. Onodera, H. Adachi, Y. Yamazaki, R. Sawa, SI. Ohba and M. Kawada
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] Synthetic lethal approach that targets c-MYC-driven cancers2022
- Author(s)
  Y. Yamazaki, SI. Ohba, T Onodera, M. Kawada and I. Momose
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] c-Mycと合成致死作用を示す低分子化合物の探索研究2022
- Author(s)
  山崎洋子、大庭俊一、小野寺威文、川田学、百瀬功
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] 神経膠芽腫由来細胞におけるErtredinによるEGFRvIIIタンパクの減少とスフェロイド形成抑制2022
- Author(s)
  渥美園子、野坂千里、川田学、小野寺威文、山崎洋子、大石智一、百瀬功、澁谷正史、内藤幹彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] Human pancreatic cancer cells are vulnerable to inhibition of redox system under nutrient deprivation2022
- Author(s)
  I. Momose, T. Onodera, H. Adachi, Y. Yamazaki, R. Sawa, SI. Ohba and M. Kawada
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] 低栄養環境に特異的ながん代謝遺伝子の発現誘導メカニズムの解明2022
- Author(s)
  小野寺威文、大庭俊一、百瀬功、川田学
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] Synthetic lethal approach that targets c-MYC-driven cancers2022
- Author(s)
  Y. Yamazaki, S. Ohba, T. Onodera, M. Kawada and I. Momose
- Organizer
  12th AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] c-Mycと合成致死作用を示す低分子化合物の探索研究2022
- Author(s)
  山崎洋子、大庭俊一、小野寺威文、川田学、百瀬功
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] Human pancreatic cancer cells are vulnerable to inhibition of redox system under nutrient deprivation2022
- Author(s)
  I. Momose, T. Onodera, H. Adachi, Y. Yamazaki, R. Sawa, S. Ohba and M. Kawada
- Organizer
  12th AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] 前立腺がんに対する新規抗アンドロゲン薬の医薬リード創製2022
- Author(s)
  阿部光、山崎洋子、坂下千春、大庭俊一、渡辺匠、百瀬功、川田学、柴﨑正勝
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] ボロン酸を利用したがん分子標的治療薬の開発2021
- Author(s)
  百瀬功、渡辺匠
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] 低栄養環境で高発現するがん特異的代謝遺伝子の探索と機能解明2021
- Author(s)
  小野寺威文、大庭俊一、百瀬功、川田学
- Organizer
  第25回日本がん分子標的治療学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] 低栄養環境で高発現するがん特異的代謝遺伝子の機能的役割2021
- Author(s)
  小野寺威文、坂本修一、百瀬功、川田学
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] 低栄養環境で高発現するがん特異的代謝遺伝子の機能解明2020
- Author(s)
  小野寺威文、大庭俊一、百瀬功、川田学
- Organizer
  第24回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] 低栄養環境で高発現するがん特異的代謝遺伝子の機能的役割2020
- Author(s)
  小野寺威文、坂本修一、百瀬功、川田学
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-20K07124
[Presentation] Inhibition of the redox system shows preferential cytotoxicity to human pancreatic cancer cells under nutrient-deprived conditions2019
- Author(s)
  Isao Momose, Takefumi Onodera, Yohko Yamazaki, Hayamitsu Adachi, Manabu Kawada
- Organizer
  第11回日米癌合同シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Inhibitory effect of a redox system by auranofin in pancreatic cancer cells under nutrient-deprived conditions2019
- Author(s)
  Takefumi Onodera, Shun-ichi Ohba, Isao Momose, Manabu Kawada
- Organizer
  第11回日米癌合同シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] 前立腺がんにおけるARバリアント発現制御に関わる因子の探索研究2018
- Author(s)
  山崎洋子、大庭俊一、百瀬功、川田学
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] 栄養飢餓選択的細胞毒性を示すAuranofinの作用機序2018
- Author(s)
  小野寺威文、百瀬功、川田学
- Organizer
  第22回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] 栄養飢餓選択的細胞毒性を示すAuranofinの作用機序2018
- Author(s)
  小野寺威文、百瀬功、川田学
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] アンドロゲンレセプタースプライシングバリアント発現制御に関わる因子の探索研究2018
- Author(s)
  山崎洋子、大庭俊一、百瀬功、川田学
- Organizer
  第22回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Auranofin, an Inhibitor of Thioredoxin Reductase, Exhibits Preferential Cytotoxicity Under Nutrient-deprived Conditions in Human Pancreatic Cancer Cells2018
- Author(s)
  T. Onodera, I. Momose, M. Kawada
- Organizer
  4th International Symposium for Medicinal Sciences (ISMS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Auranofin exhibits preferential cytotoxicity under nutrient-deprived conditions in human pancreatic cancer cells2017
- Author(s)
  Takefumi Onodera, Isao Momose, Shingo Dan, Manabu Kawada
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Auranofin exhibits preferential cytotoxicity to human pancreatic cancer cells under nutrient-deprived conditions.2017
- Author(s)
  T. Onodera, I. Momose, M. Kawada
- Organizer
  The 22nd Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy (JFCR-ISCC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Novel compounds suppressing p53-dependent growth of tumor cells2017
- Author(s)
  D. Tatsuda, I. Momose, T. Kunisada, T. Watanabe, M. Kawada, M. Shibasaki
- Organizer
  AACR-NCI-EORTC International Conference Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] AS1936: A new inhibitor of androgen receptor function in prostate cancer2017
- Author(s)
  Y. Yamazaki, S. Ohba, H. Abe, T. Watanabe, I. Momose, M. Kawada, M. Shibasaki
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] AS1936: A new inhibitor of androgen receptor function in prostate cancer2017
- Author(s)
  Yohko Yamazaki, Shun-ichi Ohba, Hikaru Abe, Takumi Watanabe, Isao Momose, Manabu Kawada, Masakatsu Shibasaki
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] Construction of screening system for new AR signaling inhibitors2016
- Author(s)
  Yohko Yamazaki, Isao Momose, Manabu Kawada, Masakatsu Shibasaki
- Organizer
  第10回日米癌合同会議
- Place of Presentation
  Hyatt Regency Maui/Maui
- Year and Date
  2016-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] p53依存的細胞増殖を阻害する新規アンスラキノン化合物2016
- Author(s)
  立田大輔、百瀬　功、川田　学
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Androprostamine A, a New Antitumor Agent for Castration Resistant Prostate Cancer2016
- Author(s)
  Yohko YAMAZAKI, Tohru MASUDA, Isao MOMOSE, Manabu KAWADA, Akio NOMOTO, Masakatsu SHIBASAKI
- Organizer
  2nd International Symposium for Medicinal Sciences
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] Papyracillic acid and penicillic acid show preferential cytotoxicity to human pancreatic cancer cells under nutrient-deprived conditions2016
- Author(s)
  Isao Momose, Yohko Yamazaki, Hayamitsu Adachi, Kengo Sumiyoshi, Manabu Kawada, Masakatsu Shibasaki
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Hyatt Regency Maui (USA)
- Year and Date
  2016-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Papyracillic acid and penicillic acid show preferential cytotoxicity under nutrient-deprived conditions.2016
- Author(s)
  I. Momose, H. Adachi, M. Kawada
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Papyracillic acidおよびpenicillic acidによる栄養飢餓選択的細胞毒性2016
- Author(s)
  百瀬功、安達勇光、川田学
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] p53-dependent growth suppression of cancer cells by coccoquinones2016
- Author(s)
  D. Tatsuda, M. Kawada, I. Momose
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Papyracillic acid およびpenicillic acidによる栄養飢餓選択的細胞毒性2016
- Author(s)
  百瀬功、安達勇光、川田学
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  別府国際コンベンションセンター（大分）
- Year and Date
  2016-05-31
- Data Source
  KAKENHI-PROJECT-15K01811
[Presentation] Construction of screening system for a novel AR signaling inhibitor2015
- Author(s)
  Yohko Yamazaki, Isao momose, Manabu Kawada, Masakatsu Shibasaki
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場/名古屋
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] 新規抗前立腺がん物質androprostamine Aの抗腫瘍活性2015
- Author(s)
  山崎洋子　増田徹　川田学　百瀬功　柴﨑正勝
- Organizer
  第19回日本がん分子標的治療学会
- Place of Presentation
  松山全日空ホテル/松山
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] 骨肉腫に対するgeraniinの腫瘍抑制効果2014
- Author(s)
  立田大輔、大庭俊一、梅沢洋二、百瀬　功、飯島正富、野本明男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] 新規抗癌剤androprostamineの抗腫瘍効果2014
- Author(s)
  山﨑洋子、増田徹、川田学、百瀬功、野本明男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Staphylotrichum boninense PF1444 株の生産する新規化合物キノフラシンの単離・構造決定2014
- Author(s)
  百瀬功、立田大輔、染野哲也、澤竜一、久保田由美子、山崎洋子、飯島正富、渡辺匠、國定孝夫、柴崎正勝、野本明男
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知県立県民文化ホール（高知）
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] p53-Mdm2結合阻害剤geraniinのin vivo抗腫瘍効果と転移抑制の解析2014
- Author(s)
  立田大輔、大庭俊一、飯島正富、百瀬　功、野本明男
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ（仙台）
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Antitumor activity of new proteasome inhibitors, tyropeptin-boronic acid derivatives.2013
- Author(s)
  Isao Momose, Hikaru Abe, Takumi Watanabe, Shun-ichi Ohba, Masatomi Iijima, Yohko Yamazaki, Tohru Masuda, Akio Nomoto
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  ハイアットリージェンシーマウイ（アメリカ）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Androprostamine: new antitumor agents for androgen-dependent prostate cancer.2013
- Author(s)
  Yohko Yamazaki, Tohru Masuda, Manabu Kawada, Isao Momose, Akio Nomoto
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  ハイアットリージェンシーマウイ（アメリカ）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Inhibition of IAP expression by barminomycin.2012
- Author(s)
  Masatomi Iijima, Daisuke Tatsuda, Isao Momose, Akio Nomoto
- Organizer
  第71回　日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] プロテアソーム阻害剤チロぺプチンボロン酸誘導体の抗腫瘍活性2012
- Author(s)
  百瀬　功、阿部　光、渡辺　匠、大庭俊一、増田　徹、池田大四郎、赤松　穰
- Organizer
  日本薬学会
- Place of Presentation
  北海道大学、札幌
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Inhibition of p53-Mdm2 interaction by ellagitannins.2012
- Author(s)
  Daisuke Tatsuda, Shun-ichi Ohba, Yoji Umezawa, Masatomi Iijima, Isao Momose, Akio Nomoto
- Organizer
  The 17th JFCR-International Symposium on Cancer Chemotherapy
- Place of Presentation
  日本科学未来館（東京）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] p53-Mdm2の結合を阻害するエラジタンニン類2012
- Author(s)
  立田大輔、飯島正富、百瀬　功、野本明男
- Organizer
  第16回学術集会　日本がん分子標的治療学会
- Place of Presentation
  西日本総合展示場AIM3F（北九州）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors.2011
- Author(s)
  Isao Momose, Hikaru Abe, Takumi Watanabe, Shun-ichi Ohba, Masatomi Iijima, Tohru Masuda, Akio Nomoto
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル東京、東京
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Decalpenic acid, a novel small molecule from Penicillium verruculosum CR37010, induces early osteoblastic markers in pluripotent mesenchymal cells through activation of retinoic acid receptor signaling pathway.2011
- Author(s)
  Shuichi Sakamoto, Fukiko Kojima, Masayuki Igarashi, Ryuichi Sawa, Maya Umekita, Yumiko Kubota, Isao Momose, Koichi Nakae, Hayamitsu Adachi, Yoshio Nishimura, Yuzuru Akamatsu
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル東京、東京
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Structure-activity relationship of tyropeptin-boronic acid derivatives: New proteasome inhibitors.2011
- Author(s)
  Hikaru Abe, Takumi Watanabe, Isao Momose, Yoshikazu Takahashi, Daishiro Ikeda, Yuzuru Akamatsu
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル東京、東京
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Inhibition of the Mdm2-p53 interaction by geraniin.2011
- Author(s)
  Daisuke Tatsuda, Masatomi Iijima, Takashi Kitayama, Isao Momose, Akio Nomoto
- Organizer
  2011 AACR-NCI-EORTC International Conference
- Place of Presentation
  Moscone Center, SanFrancisco, USA
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Antitumor effect of boronic acid derivatives of tyropeptin.2011
- Author(s)
  Isao Momose, Masatomi Iijima, Tohru Masuda, Akio Nomoto
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場、名古屋
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Tryptoquivalins: The antitumor agents for androgen-dependent prostate cancer.2011
- Author(s)
  Yohko Yamazaki, Tohru Masuda, Manabu Kawada, Isao Momose, Akio Nomoto
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル東京、東京
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Inhibition of the Mdm2-p53 interaction by geraniin.2011
- Author(s)
  Daisuke Tatsuda, Isao Momose, Masatomi Iijima, Akio Nomoto
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場、名古屋
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Geraniinはp53-Mdm2の結合を阻害する2011
- Author(s)
  立田大輔、飯島正富、百瀬　功、野本明男
- Organizer
  がん分子標的治療学会
- Place of Presentation
  ホテル日航東京、東京
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] ゲンノショウコに含まれるゲラニインの抗腫瘍効果
- Author(s)
  立田大輔、大庭俊一、梅沢洋二、百瀬功、野本明男
- Organizer
  第５回食品薬学シンポジウム
- Place of Presentation
  京都大学薬学部記念講堂（京都）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] p53-Mdm2結合阻害物質であるgeraniinのin vivo抗腫瘍効果
- Author(s)
  立田大輔、大庭俊一、梅沢洋二、飯島正富、百瀬功、野本明男
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] Androprostamine: A new antitumor agent for castration-resistant prostate cancer
- Author(s)
  Yohko Yamazaki, Tohru Masuda, Manabu Kawada, Isao Momose, and Akio Nomoto
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23510270
[Presentation] In vivo growth inhibition of osteosarcoma by geraniin
- Author(s)
  Daisuke Tatsuda, Shun-ichi Ohba, Yoji Umezawa, Msatomi Iijima, Isao Momose, Akio Nomoto
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23510270

1. YAMAZAKI Yohko (80342690)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. MASUDA Toru (90165720)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. TATSUDA Daisuke (20442569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
4. OHBA Shun-ichi (00601600)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. ABE Hikaru (10462269)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
6. 飯島正富 (10184342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. WATANABE Takumi (80270544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 武川睦寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 川田学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Momose Isao 百瀬 功

MOMOSE Isao 百瀬 功

百瀬 功 モモセ イサオ

Research Projects

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Drug discovery of new ellagitannins as next-generation therapeutic agents for osteosarcomaPrincipal Investigator

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細胞膜リン脂質リモデリングを標的とした新規抗がん剤の創出

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Development of comprehensive cancer immunotherapy using metabolism inhibitorsPrincipal Investigator

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Development of new anticancer drugs that exhibit synthetic lethal effects with c-myc on breast cancer

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Development of drugs targeting cancer metabolismPrincipal Investigator

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Elucidation of androgen-dependent growth inhibition mechanism in prostate cancer of novel small molecule compound APA

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Development of orally active proteasome inhibitors using in vivo imaging.Principal Investigator

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プロテアリーム阻害物質チロペプチン類縁体による細胞内蛋白質の変動と生物活性Principal Investigator

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[Journal Article] Deoxynortryptoquivaline: A unique antiprostate cancer agent2023

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[Journal Article] Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer2022

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[Journal Article] Boronic Acid as a Promising Class of Chemical Entity for Development of Clinical Medicine for Targeted Therapy of Cancer2022

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[Journal Article] Quinofuracins F - I, new quinofuracin derivatives produced by Staphylotrichum boninense PF14442021

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[Journal Article] Potential Anticancer Activity of Auranofin2021

Author(s)

Momose Isao 百瀬功

MOMOSE Isao 百瀬功

百瀬功モモセイサオ