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mitani kohnosuke  三谷 幸之介

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三谷 幸之介  ミタニ コウノスケ

MITANI Kohnosuke  三谷 幸之介

MITANI Kohnoske  三谷 幸之介

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Researcher Number 10270901
Other IDs
Affiliation (Current) 2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2022: 埼玉医科大学, 医学部, 教授
2010 – 2018: 埼玉医科大学, 医学部, 教授
2007: Saitama Medical University, Faculty of Medicine, Professor
2005 – 2006: 埼玉医科大学, 医学部, 助教授
1995: 東京大学, 医学部(医), 寄付講座教員
Review Section/Research Field
Principal Investigator
Human genetics / Basic Section 52050:Embryonic medicine and pediatrics-related / General medical chemistry / Human genetics
Except Principal Investigator
Laboratory animal science / Pathological medical chemistry / Digestive surgery
Keywords
Principal Investigator
ウイルスベクター / 遺伝子治療 / アデノウイルスベクター / ゲノム編集 / 相同組換え / HPRT / SCID-X1 / 遺伝子修復 / iPS細胞 / prime editing … More / iPS 細胞 / プライム編集 / 疾患モデルマーモセット / 免疫不全症 / gene therapy / Fanconi anemia / hematopoietic / gene repair / homologous recombination / adeno-associated virus vector / adenoviral vector / アデノ随伴ウイルスベクター / 造血幹細胞 / ファンコニ貧血 / CRISPR / TALEN / 遺伝子ターゲッティング / 多能性幹細胞 / 再生医療 / ヘルパーウイルス / アデノウイルス / Hprt遺伝子 / ES細胞 / 標的組み換え … More
Except Principal Investigator
UTF1 / CRISPR / ゲノム編集 / ノックイン / マーモセット / gene targeting / teratoma / cell growth / cellular differentiation / tumorigenic property / pluripotency / embryonic stem cells / ノックアウトマウス / ジーンテゲティング / 分化誘導 / 自己増殖性 / 全能性 / ジーンタゲティング / ジーンターゲティング / 奇形腫 / 細胞増殖 / 細胞分化 / 腫瘍原性 / 多能性 / ES細胞 / ファイバー改変型ベクター / ファイバー改変ベクター / 腸管アデノウイルス / 遺伝子治療 / ウイルスベクター / ウイルス治療 / 大腸癌 Less
  • Research Projects

    (10 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (11 People)
  •  新規ベクターを用いた血液系遺伝病の安全なゲノム編集治療技術の開発Principal Investigator

    • Principal Investigator
      三谷 幸之介
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Saitama Medical University
  •  Improvements in genome editing technologies for treating a marmoset model of human inherited blood disorderPrincipal Investigator

    • Principal Investigator
      Mitani Kohnosuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Saitama Medical University
  •  Establishment of an efficient gene knock-in method using adnoviral vector and CRISPR

    • Principal Investigator
      Yoshida Tetsu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Institute of Physical and Chemical Research
  •  Cancer-targeting virotherapy on human colon cancer stem-like cells by newly isolated human enteric adenoviruses

    • Principal Investigator
      Tashiro Jo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Saitama Medical University
  •  Development of a highly efficient gene targeting strategy using adenovirus-mediated delivery of donor DNA and artificial nucleasesPrincipal Investigator

    • Principal Investigator
      MITANI Kohnosuke
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Saitama Medical University
  •  ONE STEP HUMAN iPS CELL INDUCTION AND GENE TARGETING USING VIRAL VECTORSPrincipal Investigator

    • Principal Investigator
      MITANI Kohnosuke
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Saitama Medical University
  •  Role of embryonic stem cell-specific coacitvator UTF1 for tumorigenic property of ES cells

    • Principal Investigator
      OKUDA Akihiko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Saitama Medical University
  •  Development of Strategies for Gene Repair Therapy for Inherited Hematopoietic DiseasesPrincipal Investigator

    • Principal Investigator
      MITANI Kohnoske
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Saitama Medical University
  •  アデノウイルスベクターを用いた高効率標的組換え法の開発Principal Investigator

    • Principal Investigator
      三谷 幸之介
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  副作用の少ない遺伝子治療を目的としたヘルパー依存型アデノウイルスベクターの開発Principal Investigator

    • Principal Investigator
      三谷 幸之介
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human genetics
    • Research Institution
      The University of Tokyo

All 2018 2015 2013 2012 2005 Other

All Journal Article Presentation

  • [Journal Article] 特集 遺伝子治療における技術革新の現状と課題 10.ゲノム編集技術の導入による遺伝子治療の革命2018

    • Author(s)
      三谷幸之介
    • Journal Title

      医薬ジャーナル

      Volume: 54 Issue: 1 Pages: 107-110

    • DOI

      10.20837/1201801107

    • ISSN
      0287-4741
    • Year and Date
      2018-01-01
    • Data Source
      KAKENHI-PROJECT-16K08642
  • [Journal Article] ゲノム編集の臨床応用の概要2018

    • Author(s)
      三谷幸之介
    • Journal Title

      Farumashia

      Volume: 54 Issue: 2 Pages: 118-122

    • DOI

      10.14894/faruawpsj.54.2_118

    • NAID

      130006329197

    • ISSN
      0014-8601, 2189-7026
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-16K08642
  • [Journal Article] Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors2005

    • Author(s)
      Ohbayashi F, Balamotis MA, Kishimoto A, Aizawa E, Diaz A, Hasty P, Graham FL, Caskey CT, Mitani K
    • Journal Title

      Proc Natl Acad Sci USA 102-38

      Pages: 13628-13633

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590290
  • [Presentation] ゲノム編集技術のヒト臨床応用の現状2018

    • Author(s)
      三谷幸之介
    • Organizer
      日本ゲノム編集学会 第3回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08642
  • [Presentation] ゲノム編集技術の臨床応用に向けて2018

    • Author(s)
      三谷幸之介
    • Organizer
      21世紀の医療とテクノロジーの展望シンポジウム(UCLA-Japan シンポジウム)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08642
  • [Presentation] ウイルスベクターを駆使したヒトiPS細胞誘導と遺伝子修復の時間的効率化2015

    • Author(s)
      三谷幸之介,太田尚志,二橋望,大高真奈美,中西真人
    • Organizer
      第14回日本再生医療学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-03-19
    • Data Source
      KAKENHI-PROJECT-24590405
  • [Presentation] Consecutive Human iPS Cell Induction And Gene Targeting Using Viral Vectors2013

    • Author(s)
      Ko Mitani
    • Organizer
      CiRA International Symposium 2013
    • Place of Presentation
      京都大学(京都府)
    • Data Source
      KAKENHI-PROJECT-24590405
  • [Presentation] ONE STEP HUMAN iPS CELL INDUCTION AND GENE TARGETING USING VIRAL VECTORS2012

    • Author(s)
      Ko Mitani, Emi Aizawa, Manami Ohtaka, Ken Nishimura, Mahito Nakanishi
    • Organizer
      日本遺伝子治療学会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-22659061
  • [Presentation] One Step Human iPS Cell Induction And Enhanced Gene Targeting Using Viral Vectors And TALE Nucleases2012

    • Author(s)
      Ko Mitani, Emi Aizawa, Claudio Mussolino, Manami Ohtaka, Ken Nishimura, Toni Cathomen, Mahito Nakanishi
    • Organizer
      米国遺伝子細胞治療学会
    • Place of Presentation
      米国ペンシルバニア州
    • Data Source
      KAKENHI-PROJECT-22659061
  • [Presentation] 下痢症由来新規アデノウイルス血清型の解析とベクター化

    • Author(s)
      三谷幸之介
    • Organizer
      日本ウイルス学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-26462024
  • 1.  ISHII Naoto (60291267)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  Tashiro Jo (40601258)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  OHBAYASHI Fumi (60406527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  OKUDA Akihiko (60201993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NOMURA Jun (70406528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Yoshida Tetsu (00365438)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  田代 文 (40136213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  山口 茂樹 (30254220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  岸本 充弘 (70383289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  汲田 和歌子 (50549128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  徳永 暁憲 (70549451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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