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Shibahara Naotoshi  柴原 直利

ORCIDConnect your ORCID iD *help
… Alternative Names

柴原 直利  シバハラ ナオトシ

SIBAHARA Naotoshi  柴原 直利

SHIBAHARA Naotoshi  柴原 直利

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Researcher Number 10272907
Other IDs
External Links
Affiliation (Current) 2022: 富山大学, 学術研究部薬学・和漢系, 教授
Affiliation (based on the past Project Information) *help 2021: 富山大学, 学術研究部薬学・和漢系, 教授
2009 – 2018: 富山大学, 和漢医薬学総合研究所, 教授
2005 – 2007: 富山大学, 和漢医薬学総合研究所, 教授
2001 – 2003: 富山医科薬科大学, 和漢薬研究所, 教授
Review Section/Research Field
Principal Investigator
General internal medicine (including Psychosomatic medicine) / General internal medicine(including psychosomatic medicine)
Except Principal Investigator
General internal medicine (including Psychosomatic medicine) / Environmental pharmacy / Medical sociology / General internal medicine(including psychosomatic medicine) / Basic Section 58010:Medical management and medical sociology-related
Keywords
Principal Investigator
生薬 / プロテオーム解析 / 鍼灸治療 / プロテオーム / 糖尿病性細小血管症 / 血小板マイクロパーティクル / 活性型血小板 / 牛膝 / 紅花 / 丹参 … More / nitrate oxide synthase / 血小板マイクロパーティクル / 下痢 / 五苓散 / アクアポリン / 漢方薬 … More
Except Principal Investigator
漢方薬 / 東洋医学 / 認知症モデル / メディエータ / 脳虚血 / 加齢 / dementia model / Kampo medicine / vascular endothelial growth factor / neuroplasticity / aging / platelet derived growth factor / ischemia / mediator(s) / anti-dementia drug / emotional disoders / Senescence-accelerated mouse / 薬用植物 / 分子系統学 / 品質評価 / 認知症 / 生活習慣病 / 刺五加 / 中国 / 芍薬 / 国際研究者交流 / 褥瘡 / 老化 / 漢方医学 / 和漢診療 / 教育 / コア・カリキュラム / コア・テキスト / グローバルスタンダード / 和漢薬 / CAM(代替療法) / Kampo Medicine / Japanese Oriental Medicine / Education / Core Curriculum / Core text book / Global standard / Herbal Medicine / Complementary and Alternative medicine / ドラッグ・リポジショニング / 複雑系 / 医薬ビッグデータ / 機械学習 / in silico結合シミュレーション / インシリコ / 機械学習手法 / 結合シミュレーション / 標的タンパク質探索 / 実験薬理学的検証 / 和漢医薬学 / リポジショニング / 標的タンパク質 / 眼球運動計測 / 漢方専門医 / 臨床能力 / 医学教育 Less
  • Research Projects

    (9 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (29 People)
  •  眼球運動計測に基づく漢方専門医の広角的臨床能力の定量化と漢方医学教育への応用

    • Principal Investigator
      山田 理絵
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      University of Toyama
  •  Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases

    • Principal Investigator
      Kadowaki Makoto
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Research on diarrhea-improving effect of Goreisan via the expression of aquaporins in intestinePrincipal Investigator

    • Principal Investigator
      Shibahara Naotoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Exploratory Research for crude drugs having activated platelet-mediated inhibiting effect on diabetic microangiopathyPrincipal Investigator

    • Principal Investigator
      SHIBAHARA Naotoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Analysis on genetic, chemical and pharmacological diversity of medicinal plants, towards sustainable uses of traditional medicines

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      University of Toyama
  •  Efficacy of Japanese Kampo medicine for pressure-loading skin ulcer

    • Principal Investigator
      HIKIAMI Hiroaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine

    • Principal Investigator
      MATSUMOTO Kinzo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  患者血清のプロテオミクス解析による鍼灸治療効果の客観的評価法の構築Principal Investigator

    • Principal Investigator
      柴原 直利
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Construction of educational global standardin Kampo Medicine

    • Principal Investigator
      SHIMADA Yutaka, 寺澤 捷年
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical sociology
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

All 2017 2011 2010 2009 Other

All Journal Article Presentation

  • [Journal Article] Diosgenin-Rich Yam Extract Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study of Healthy Adults.2017

    • Author(s)
      Tohda C., Yang X., Matsui M., Inada Y., Kadomoto E., Nakada S., Watari H., Shibahara N.
    • Journal Title

      Nutrients

      Volume: 9 Pages: 1160-1160

    • DOI

      10.3390/nu9101160

    • NAID

      120006375104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558
  • [Journal Article] Ameliorative effects of yokukansan on learning and memory deficits in olfactory bulbectomized mice2011

    • Author(s)
      Yamada M., Hayashida M., Zhao Q., Shibahara N., Tanaka K., Miyata T., Matsumoto K.
    • Journal Title

      J Ethnopharmacol. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Journal Article] Cinnamaldehide and paeonol increase HIF-1αactivity in proximal tubular epithelial cells under hypoxia2011

    • Author(s)
      Oka H., Goto H., Koizumi K., Nogami T., Watari H., Nakamura S., Zhou Y., Sakurai H., Shibahara N., Saiki I., Shimada Y.
    • Journal Title

      J. Trad. Med.

      Volume: 28 Pages: 149-157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406004
  • [Journal Article] Traditional Japanese formula kigikenchuto accelerates healing of pressure-loading skin ulcer in rats. Evid Based Complement Alternat Med2011

    • Author(s)
      Kimura M., Shibahara N., Hikiami H., Yoshida T., Jo M., Kaneko M., Nogami T., Fujimoto M., Goto H., and Shimada Y
    • Journal Title

      Volume 2011

      Pages: 9-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590759
  • [Journal Article] Cinnamaldehide and paeonol increase HIF-1α activity in proximal tubular epithelial cells under hypoxia2011

    • Author(s)
      Oka H., Goto H., Koizumi K., Nogami T., Watari H., Nakamura S., Zhou Y., Sakurai H., Shibahara N., Saiki I., Shimada Y.
    • Journal Title

      J.Trad.Med.

      Volume: 28 Pages: 149-157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406004
  • [Presentation] 正常ラット腸管における五苓散のAQPsを介した水分調節に対する検討2017

    • Author(s)
      呉伊羲,木村真梨,成田絢香,サランチチグ,江藤武志,入矢美沙, 条美智, 柴原直利
    • Organizer
      和漢医薬学会
    • Data Source
      KAKENHI-PROJECT-15K08901
  • [Presentation] 五苓散の基礎と臨床~ 脳外科領域での有用性について2017

    • Author(s)
      柴原直利
    • Organizer
      第34回和漢医薬学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05276
  • [Presentation] 五苓散の効果発現におけるアクアポリンの関与2017

    • Author(s)
      柴原直利,条美智子
    • Organizer
      和漢医薬学会
    • Data Source
      KAKENHI-PROJECT-15K08901
  • [Presentation] 高脂肪食負荷ラットに対する和漢薬の効果についての検討2011

    • Author(s)
      藤本孝子, 亀井貴志, 条美智子, 後藤博三, 嶋田豊, 柴原直利
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山県民会館(富山)
    • Data Source
      KAKENHI-PROJECT-21406004
  • [Presentation] 加圧負荷褥瘡モデルラットにおける帰耆建中湯の効果(第4報)2011

    • Author(s)
      木村真梨,条美智子,野上達也,藤本誠,引網宏彰,後藤博三,柴原直利,嶋田豊
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-21590759
  • [Presentation] 当帰芍薬散:伝統的剤形の有用性と原料生薬の品質2011

    • Author(s)
      島田佳代子, 中村勇斗, 川瀬雅也, 柴原直利, 小松かつ子, 高橋京子
    • Organizer
      平成23年度日本東洋医学会関西支部例会
    • Place of Presentation
      大阪国際交流センター(大阪)
    • Year and Date
      2011-10-30
    • Data Source
      KAKENHI-PROJECT-21406004
  • [Presentation] 「伝統医薬データベース」の構築2011

    • Author(s)
      柴原直利, 東田千尋, 朱〓, 櫻井宏明, 数馬恒平, 山本武, 小泉桂一, 紺野勝弘, 門脇真, 小松かつ子
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山県民会館(富山)
    • Data Source
      KAKENHI-PROJECT-21406004
  • [Presentation] Ameliorative effect of yokukansan on learning and memory deficits in olfactory bulbectomized mice used as an Alzheimer disease model2011

    • Author(s)
      山田麻利名, 林田未希, 趙〓, 柴原直利, 宮田健, 松本欣三
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] マウスにおける抗癌薬誘発疼痛に対する5種類の漢方方剤の薬効評価2011

    • Author(s)
      北村亮, 安東嗣修, 伏見裕利, 小松かつ子, 柴原直利
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山県民会館(富山)
    • Data Source
      KAKENHI-PROJECT-21406004
  • [Presentation] Natural Medicine Research for the Next Decade : New Challenges and Future Collaboration2010

    • Author(s)
      山田麻利名, 林田未希, 柴原直利, 宮田健, 松本欣三
    • Organizer
      The 9th JSPS-NRCT Joint Semina
    • Place of Presentation
      Bangkok, Thailand
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] 食事誘発性糖尿病モデルラットに対する和漢薬の効果2010

    • Author(s)
      亀井貴志, 藤本孝子, 条美智子, 木村真梨, 金子真利亜, 後藤博三, 嶋田豊, 柴原直利
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都薬科大学(京都)
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-21406004
  • [Presentation] 加圧負荷褥瘡モデルラットにおける帰耆建中湯の効果(第3報)2010

    • Author(s)
      木村真梨,金子真利亜,条美智子,野上達也,藤本誠,引網宏彰,後藤博三,嶋田豊,柴原直利
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21590759
  • [Presentation] 嗅球摘出マウスの学習記憶障害に対する抑肝散の改善効果とその機序2010

    • Author(s)
      山田麻利名, 林田未希, 柴原直利, 松本欣三
    • Organizer
      日本薬学会北陸支部第122回例会
    • Place of Presentation
      金沢
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] 加圧負荷褥瘡モデルラットにおける帰耆建中湯の効果(第2報)2009

    • Author(s)
      木村真梨,中塚友貴子,条美智子,引網宏彰,後藤博三,嶋田豊,柴原直利
    • Organizer
      第26回和漢医薬学会学術大会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-21590759
  • [Presentation] 恐怖条件付けによるマウスのフリージング行動に対する数種漢方方剤の影響2009

    • Author(s)
      村上孝寿, 山田麻利名, 東田道久, 柴原直利, 松本欣三
    • Organizer
      第26回和漢医薬学会大会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] 糖尿病モデルにおける活性型血小板・血小板マイクロパーティクルに対する駆瘀血薬の効果

    • Author(s)
      木村 真梨, 三島怜, 条美智子, 野上達也, 藤本誠, 引網宏彰, 嶋田豊, 柴原直利
    • Organizer
      第31回和漢医薬学会学術大会
    • Place of Presentation
      千葉幕張メッセ
    • Year and Date
      2014-08-30 – 2014-08-31
    • Data Source
      KAKENHI-PROJECT-24590880
  • 1.  HIKIAMI Hiroaki (70345586)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  SHIMADA Yutaka (80251891)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  TANAKA Ken (60418689)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  TOHDA Chihiro (10272931)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  MATSUMOTO Kinzo (10114654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 6.  TSUNEYAMA Koichi (10293341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MURAKAMI Yukihisa (00377269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KOMATSU Katsuko (50225570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  ZHU Shu (20377360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SAKAI Shinya (30324049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  GOTO Hirozo (40313598)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SEKIYA Nobuyasu (40345575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Kadowaki Makoto (20305709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  藤本 孝子 (70377266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  寺澤 捷年 (20126535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  喜多 敏明 (00283078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  林 周作 (10548217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  山西 芳裕 (60437267)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  山本 武 (70316181)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  梅嵜 雅人 (80534370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  山田 理絵 (70336709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  藤本 誠 (30377337)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  貝沼 茂三郎 (30361968)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  渡り 英俊 (70757351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KIMURA Mari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  WU Yixi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 27.  SAREN, Qiqige
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 28.  朱 しゅう
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  村上 孝寿
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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