Shibahara Naotoshi 柴原直利

… Alternative Names

柴原直利シバハラナオトシ

SIBAHARA Naotoshi 柴原直利

SHIBAHARA Naotoshi 柴原直利

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Researcher Number	10272907
Other IDs
External Links
Affiliation (Current)	2022: 富山大学, 学術研究部薬学・和漢系, 教授
Affiliation (based on the past Project Information) *help	2021: 富山大学, 学術研究部薬学・和漢系, 教授 2009 – 2018: 富山大学, 和漢医薬学総合研究所, 教授 2005 – 2007: 富山大学, 和漢医薬学総合研究所, 教授 2001 – 2003: 富山医科薬科大学, 和漢薬研究所, 教授
Review Section/Research Field	Principal Investigator General internal medicine (including Psychosomatic medicine) / General internal medicine(including psychosomatic medicine) Except Principal Investigator General internal medicine (including Psychosomatic medicine) / Environmental pharmacy / Medical sociology / General internal medicine(including psychosomatic medicine) / Basic Section 58010:Medical management and medical sociology-related
Keywords	Principal Investigator 生薬 / プロテオーム解析 / 鍼灸治療 / プロテオーム / 糖尿病性細小血管症 / 血小板マイクロパーティクル / 活性型血小板 / 牛膝 / 紅花 / 丹参 … More / nitrate oxide synthase / 血小板ﾏｲｸﾛﾊﾟｰﾃｨｸﾙ / 下痢 / 五苓散 / アクアポリン / 漢方薬 … More Except Principal Investigator 漢方薬 / 東洋医学 / 認知症モデル / メディエータ / 脳虚血 / 加齢 / dementia model / Kampo medicine / vascular endothelial growth factor / neuroplasticity / aging / platelet derived growth factor / ischemia / mediator(s) / anti-dementia drug / emotional disoders / Senescence-accelerated mouse / 薬用植物 / 分子系統学 / 品質評価 / 認知症 / 生活習慣病 / 刺五加 / 中国 / 芍薬 / 国際研究者交流 / 褥瘡 / 老化 / 漢方医学 / 和漢診療 / 教育 / コア・カリキュラム / コア・テキスト / グローバルスタンダード / 和漢薬 / CAM(代替療法) / Kampo Medicine / Japanese Oriental Medicine / Education / Core Curriculum / Core text book / Global standard / Herbal Medicine / Complementary and Alternative medicine / ドラッグ・リポジショニング / 複雑系 / 医薬ビッグデータ / 機械学習 / in silico結合シミュレーション / インシリコ / 機械学習手法 / 結合シミュレーション / 標的タンパク質探索 / 実験薬理学的検証 / 和漢医薬学 / リポジショニング / 標的タンパク質 / 眼球運動計測 / 漢方専門医 / 臨床能力 / 医学教育 Less

眼球運動計測に基づく漢方専門医の広角的臨床能力の定量化と漢方医学教育への応用
- Principal Investigator
  
  山田理絵
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  University of Toyama
Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases
- Principal Investigator
  
  Kadowaki Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
Research on diarrhea-improving effect of Goreisan via the expression of aquaporins in intestinePrincipal Investigator
- Principal Investigator
  
  Shibahara Naotoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
Exploratory Research for crude drugs having activated platelet-mediated inhibiting effect on diabetic microangiopathyPrincipal Investigator
- Principal Investigator
  
  SHIBAHARA Naotoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Analysis on genetic, chemical and pharmacological diversity of medicinal plants, towards sustainable uses of traditional medicines
- Principal Investigator
  
  KOMATSU Katsuko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Toyama
Efficacy of Japanese Kampo medicine for pressure-loading skin ulcer
- Principal Investigator
  
  HIKIAMI Hiroaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine
- Principal Investigator
  
  MATSUMOTO Kinzo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
患者血清のプロテオミクス解析による鍼灸治療効果の客観的評価法の構築Principal Investigator
- Principal Investigator
  
  柴原直利
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Construction of educational global standardin Kampo Medicine
- Principal Investigator
  
  SHIMADA Yutaka, 寺澤捷年
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical sociology
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

All 2017 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Diosgenin-Rich Yam Extract Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study of Healthy Adults.2017
- Author(s)
  Tohda C., Yang X., Matsui M., Inada Y., Kadomoto E., Nakada S., Watari H., Shibahara N.
- Journal Title
  
  Nutrients
  
  Volume: 9 Pages: 1160-1160
- DOI
  10.3390/nu9101160
- NAID
  120006375104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558
[Journal Article] Ameliorative effects of yokukansan on learning and memory deficits in olfactory bulbectomized mice2011
- Author(s)
  Yamada M., Hayashida M., Zhao Q., Shibahara N., Tanaka K., Miyata T., Matsumoto K.
- Journal Title
  
  J Ethnopharmacol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390197
[Journal Article] Cinnamaldehide and paeonol increase HIF-1αactivity in proximal tubular epithelial cells under hypoxia2011
- Author(s)
  Oka H., Goto H., Koizumi K., Nogami T., Watari H., Nakamura S., Zhou Y., Sakurai H., Shibahara N., Saiki I., Shimada Y.
- Journal Title
  
  J. Trad. Med.
  
  Volume: 28 Pages: 149-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406004
[Journal Article] Traditional Japanese formula kigikenchuto accelerates healing of pressure-loading skin ulcer in rats. Evid Based Complement Alternat Med2011
- Author(s)
  Kimura M., Shibahara N., Hikiami H., Yoshida T., Jo M., Kaneko M., Nogami T., Fujimoto M., Goto H., and Shimada Y
- Journal Title
  
  Volume 2011
  
  Pages: 9-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590759
[Journal Article] Cinnamaldehide and paeonol increase HIF-1α activity in proximal tubular epithelial cells under hypoxia2011
- Author(s)
  Oka H., Goto H., Koizumi K., Nogami T., Watari H., Nakamura S., Zhou Y., Sakurai H., Shibahara N., Saiki I., Shimada Y.
- Journal Title
  
  J.Trad.Med.
  
  Volume: 28 Pages: 149-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406004
[Presentation] 正常ラット腸管における五苓散のAQPsを介した水分調節に対する検討2017
- Author(s)
  呉伊羲，木村真梨，成田絢香，サランチチグ，江藤武志，入矢美沙, 条美智, 柴原直利
- Organizer
  和漢医薬学会
- Data Source
  KAKENHI-PROJECT-15K08901
[Presentation] 五苓散の基礎と臨床～　脳外科領域での有用性について2017
- Author(s)
  柴原直利
- Organizer
  第34回和漢医薬学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] 五苓散の効果発現におけるアクアポリンの関与2017
- Author(s)
  柴原直利，条美智子
- Organizer
  和漢医薬学会
- Data Source
  KAKENHI-PROJECT-15K08901
[Presentation] 高脂肪食負荷ラットに対する和漢薬の効果についての検討2011
- Author(s)
  藤本孝子, 亀井貴志, 条美智子, 後藤博三, 嶋田豊, 柴原直利
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山県民会館(富山)
- Data Source
  KAKENHI-PROJECT-21406004
[Presentation] 加圧負荷褥瘡モデルラットにおける帰耆建中湯の効果(第4報)2011
- Author(s)
  木村真梨,条美智子,野上達也,藤本誠,引網宏彰,後藤博三,柴原直利,嶋田豊
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21590759
[Presentation] 当帰芍薬散:伝統的剤形の有用性と原料生薬の品質2011
- Author(s)
  島田佳代子, 中村勇斗, 川瀬雅也, 柴原直利, 小松かつ子, 高橋京子
- Organizer
  平成23年度日本東洋医学会関西支部例会
- Place of Presentation
  大阪国際交流センター(大阪)
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-21406004
[Presentation] 「伝統医薬データベース」の構築2011
- Author(s)
  柴原直利, 東田千尋, 朱〓, 櫻井宏明, 数馬恒平, 山本武, 小泉桂一, 紺野勝弘, 門脇真, 小松かつ子
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山県民会館(富山)
- Data Source
  KAKENHI-PROJECT-21406004
[Presentation] Ameliorative effect of yokukansan on learning and memory deficits in olfactory bulbectomized mice used as an Alzheimer disease model2011
- Author(s)
  山田麻利名, 林田未希, 趙〓, 柴原直利, 宮田健, 松本欣三
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] マウスにおける抗癌薬誘発疼痛に対する5種類の漢方方剤の薬効評価2011
- Author(s)
  北村亮, 安東嗣修, 伏見裕利, 小松かつ子, 柴原直利
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山県民会館(富山)
- Data Source
  KAKENHI-PROJECT-21406004
[Presentation] Natural Medicine Research for the Next Decade : New Challenges and Future Collaboration2010
- Author(s)
  山田麻利名, 林田未希, 柴原直利, 宮田健, 松本欣三
- Organizer
  The 9th JSPS-NRCT Joint Semina
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] 食事誘発性糖尿病モデルラットに対する和漢薬の効果2010
- Author(s)
  亀井貴志, 藤本孝子, 条美智子, 木村真梨, 金子真利亜, 後藤博三, 嶋田豊, 柴原直利
- Organizer
  第27回和漢医薬学会学術大会
- Place of Presentation
  京都薬科大学(京都)
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21406004
[Presentation] 加圧負荷褥瘡モデルラットにおける帰耆建中湯の効果(第3報)2010
- Author(s)
  木村真梨,金子真利亜,条美智子,野上達也,藤本誠,引網宏彰,後藤博三,嶋田豊,柴原直利
- Organizer
  第27回和漢医薬学会学術大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590759
[Presentation] 嗅球摘出マウスの学習記憶障害に対する抑肝散の改善効果とその機序2010
- Author(s)
  山田麻利名, 林田未希, 柴原直利, 松本欣三
- Organizer
  日本薬学会北陸支部第122回例会
- Place of Presentation
  金沢
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] 加圧負荷褥瘡モデルラットにおける帰耆建中湯の効果(第2報)2009
- Author(s)
  木村真梨,中塚友貴子,条美智子,引網宏彰,後藤博三,嶋田豊,柴原直利
- Organizer
  第26回和漢医薬学会学術大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590759
[Presentation] 恐怖条件付けによるマウスのフリージング行動に対する数種漢方方剤の影響2009
- Author(s)
  村上孝寿, 山田麻利名, 東田道久, 柴原直利, 松本欣三
- Organizer
  第26回和漢医薬学会大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] 糖尿病モデルにおける活性型血小板・血小板マイクロパーティクルに対する駆瘀血薬の効果
- Author(s)
  木村真梨, 三島怜, 条美智子, 野上達也, 藤本誠, 引網宏彰, 嶋田豊, 柴原直利
- Organizer
  第31回和漢医薬学会学術大会
- Place of Presentation
  千葉幕張メッセ
- Year and Date
  2014-08-30 – 2014-08-31
- Data Source
  KAKENHI-PROJECT-24590880

1. HIKIAMI Hiroaki (70345586)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. SHIMADA Yutaka (80251891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TANAKA Ken (60418689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. TOHDA Chihiro (10272931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. MATSUMOTO Kinzo (10114654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. TSUNEYAMA Koichi (10293341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MURAKAMI Yukihisa (00377269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOMATSU Katsuko (50225570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. ZHU Shu (20377360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAKAI Shinya (30324049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. GOTO Hirozo (40313598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SEKIYA Nobuyasu (40345575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Kadowaki Makoto (20305709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤本孝子 (70377266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 寺澤捷年 (20126535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 喜多敏明 (00283078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 林周作 (10548217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山西芳裕 (60437267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 山本武 (70316181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 梅嵜雅人 (80534370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山田理絵 (70336709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 藤本誠 (30377337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 貝沼茂三郎 (30361968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 渡り英俊 (70757351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KIMURA Mari

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. WU Yixi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. SAREN, Qiqige

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. 朱しゅう

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 村上孝寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibahara Naotoshi 柴原 直利

柴原 直利 シバハラ ナオトシ

SIBAHARA Naotoshi 柴原 直利

SHIBAHARA Naotoshi 柴原 直利

Research Projects

Research Products

Co-Researchers

眼球運動計測に基づく漢方専門医の広角的臨床能力の定量化と漢方医学教育への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on diarrhea-improving effect of Goreisan via the expression of aquaporins in intestinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploratory Research for crude drugs having activated platelet-mediated inhibiting effect on diabetic microangiopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on genetic, chemical and pharmacological diversity of medicinal plants, towards sustainable uses of traditional medicines

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Efficacy of Japanese Kampo medicine for pressure-loading skin ulcer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

患者血清のプロテオミクス解析による鍼灸治療効果の客観的評価法の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of educational global standardin Kampo Medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Diosgenin-Rich Yam Extract Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study of Healthy Adults.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Ameliorative effects of yokukansan on learning and memory deficits in olfactory bulbectomized mice2011

Author(s)

Journal Title

Data Source

[Journal Article] Cinnamaldehide and paeonol increase HIF-1αactivity in proximal tubular epithelial cells under hypoxia2011

Author(s)

Journal Title

Data Source

[Journal Article] Traditional Japanese formula kigikenchuto accelerates healing of pressure-loading skin ulcer in rats. Evid Based Complement Alternat Med2011

Author(s)

Journal Title

Data Source

[Journal Article] Cinnamaldehide and paeonol increase HIF-1α activity in proximal tubular epithelial cells under hypoxia2011

Shibahara Naotoshi 柴原直利

柴原直利シバハラナオトシ

SIBAHARA Naotoshi 柴原直利

SHIBAHARA Naotoshi 柴原直利

[Presentation] 五苓散の基礎と臨床～　脳外科領域での有用性について2017