KUBOTA Toru 久保田耐

… Alternative Names

久保田耐クボタトオル

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Researcher Number	10274929
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所ハンセン病研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 国立健康危機管理研究機構, ハンセン病研究センター感染制御部, 主任研究官 2014 – 2015: 国立感染症研究所, その他部局等, 研究員 2013: 国立感染症研究所, ウイルス第3部, 研究員 2010 – 2012: 国立感染症研究所, ウイルス第三部, 主任研究官 1998 – 1999: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Virology / Basic Section 53050:Dermatology-related / Bacteriology (including Mycology)
Keywords	Principal Investigator IKKε / TBK1 / 翻訳後修飾 / in vitro培養法 / 人工合成培地 / らい菌 / タンパク質リン酸化 / リン酸化 / RGSタンパク質 / GPCR … More / RGS / タンパク質翻訳後修飾 / 自然免疫 / ウイルス / TANK / SUMO / SUMO化 / インターフェロン / ウイルス感染応答 / neurotoxin / Clostridium botulinum / クロストリジウム属 / 神経毒素 / ボツリヌス菌 Less

Research Projects
(4 results)
Research Products
(6 results)

異種抗酸菌のマイコバクチンを用いたらい菌のin vitro培養法の開発Principal Investigator
- Principal Investigator
  
  久保田耐
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Japan Institute for Health Security
Study on regulatory mechanism of TBK1Principal Investigator
- Principal Investigator
  
  Toru Kubota
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Novel regulatory mechanisms against virus infection: activation of dignal transduction through protein SUMO modificationPrincipal Investigator
- Principal Investigator
  
  KUBOTA Toru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
遺伝子導入系を用いたボツリヌス菌神経毒素産生調節機構の解析Principal Investigator
- Principal Investigator
  
  久保田耐
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Sapporo Medical University

All 2014 2011 2010

All Journal Article Presentation

[Journal Article] Functionally Distinct Effects of the C-Terminal Regions of IKKε and TBK1 on Type I IFN Production.2014
- Author(s)
  Nakatsu Y, Matsuoka M, Chang TH, Otsuki N, Noda M, Kimura H, Sakai K, Kato H, Takeda M, Kubota T.
- Journal Title
  
  PLoS One
  
  Volume: 9(4) Issue: 4 Pages: 1-7
- DOI
  10.1371/journal.pone.0094999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460582
[Journal Article] Piasy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms.2011
- Author(s)
  Kubota T, Matsuoka M, Xu S, Otsuki N, Takeda M, Kato A, Ozato K.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286(10) Pages: 8165-8175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590424
[Journal Article] PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms2011
- Author(s)
  Kubota T, Matsuoka M, Xu S, Otsuki N, Takeda M, Kato A, Ozato K
- Journal Title
  
  Jounal of Biological Chemistry
  
  Volume: 286(10) Pages: 8165-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590424
[Journal Article] PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms2011
- Author(s)
  久保田耐, 他
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Pages: 8165-8175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590424
[Presentation] Piasy inhibits virus induced type I Interferon production.2010
- Author(s)
  Kubota T, Matsuoka M, Xu S, Takeda M, Shuai K, Kato A, Ozato K
- Organizer
  8^<th> Joint Annual Meeting of the ISC/ISICR
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22590424
[Presentation] PIASY INHIBITS VIRUS INDUCED TYPE I INTERFERON PRODUCTION.2010
- Author(s)
  Kubota T, Matsuoka M, Xu S, Otsuki N, Takeda M, Kato A, Ozato K.
- Organizer
  Cytokines Chicago 2010
- Place of Presentation
  アメリカ合衆国シカゴ
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-22590424

KUBOTA Toru 久保田 耐

久保田 耐 クボタ トオル

Research Projects

Research Products

異種抗酸菌のマイコバクチンを用いたらい菌のin vitro培養法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on regulatory mechanism of TBK1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel regulatory mechanisms against virus infection: activation of dignal transduction through protein SUMO modificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝子導入系を用いたボツリヌス菌神経毒素産生調節機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Functionally Distinct Effects of the C-Terminal Regions of IKKε and TBK1 on Type I IFN Production.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Piasy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms.2011

Author(s)

Journal Title

Data Source

[Journal Article] PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms2011

Author(s)

Journal Title

Data Source

[Journal Article] PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms2011

Author(s)

Journal Title

Data Source

[Presentation] Piasy inhibits virus induced type I Interferon production.2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] PIASY INHIBITS VIRUS INDUCED TYPE I INTERFERON PRODUCTION.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KUBOTA Toru 久保田耐

久保田耐クボタトオル