Okada Motohiro 岡田元宏

… Alternative Names

OKADA Motohiro 岡田元宏

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Researcher Number	10281916
Other IDs
External Links
Affiliation (Current)	2022: 三重大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2022: 三重大学, 医学系研究科, 教授 2011 – 2015: 三重大学, 医学(系)研究科(研究院), 教授 2007 – 2012: Mie University, 大学院・医学系研究科, 教授 2007 – 2008: 三重大学, 大学院・医学研究科, 教授 2006: 三重大学, 医学部, 教授 … More 2006: 三重大学, 大学院医学系研究科, 教授 2004 – 2006: Hirosaki University, University Hospital, Lecturer, 医学部附属病院, 講師 2003 – 2006: Hirosaki University, School of Medicine, Lecture, 医学部, 講師 2004: 弘前大学, 医学部・附属病院, 講師 2002: Hirosaki University, School of Medicine, Assistant Professor, 医学部, 助教授 1997 – 2002: 弘前大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Psychiatric science / Psychiatric science / Basic Section 52030:Psychiatry-related Except Principal Investigator Biological Sciences / Neurology / Laboratory animal science / Psychiatric science / Linguistics / 広領域 / Pediatrics / Psychiatric science / Basic Section 58060:Clinical nursing-related
Keywords	Principal Investigator てんかん / 神経伝達 / セロトニン / カルシウム / 開口分泌 / グルタミン酸 / シナプス蛋白 / 蛋白相互作用 / トランスジェニックラット / 遺伝子 … More / 機能性疾患 / ドーパミン / 感情障害 / カルシウムイオンチャネル / ドパミン / 病態 / 分子生物学 / 認知機能 / 遺伝子改変モデル動物 / ノックダウンマウス / イオンチャネル / アセチルコリン / 抗てんかん薬 / 情報伝達 / アストロサイト / 三者間伝達 / ADHD / グリア / アデノシン / ATP / マイクロダイアリーシス / 中枢神経系 / SNARE蛋白 / synprint蛋白 / カルバマゼピン / ゾニサミド / カリウム / spreading depression / 不安障害 / GABA / 神経伝逹 / 前頭葉 / 分子病態 / 精神薬理学 / 統合失調症 / 認知症 / 神経 / 病態生理 / 自閉症 / 情動安定化 / 認知 … More Except Principal Investigator てんかん / Epilepsy / GABA / 開口分泌 / 神経科学 / ADNFLE / BFNC / GEFS+ / 遺伝子 / 感情障害 / 遺伝子改変動物 / 睡眠 / ゲノム / 脳神経疾患 / チャネル病 / 組換え動物 / 熱性けいれん / シグナル伝達 / グルタミン酸 / 神経伝達 / シナプス蛋白 / カルシウムイオンチャネル / 蛋白相互作用 / exocytosis / synprint / モデル動物 / チャネル / チャネロパチー / 遺伝子組換え / 神経伝達物質 / Channel / Neurotransmitter / μ3B / S284L α4β2-nAChR / 遺伝学 / 脳神経 / 脳神経学 / 脳神経疾愚 / 個別化治療 / gene / polymorohism / CYP / ion channel / receptor / treatment / transporter / 不安障害 / アセチルコリン / 生理学 / 薬理学 / 発達 / マイクロアレイ / 脳・神経 / 疾患モデル / イオンチャネル / AChチャネル / 生得的言語知識 / 統語的構造条件 / 母語獲得 / 脳科学 / 光トポグラフィー / 言語学 / 組み換え動物 / GEFS^+ / CEFS+ / Channel disease / transgenic animals / febrile seizures / セロトニン / ドパミン / Mood Disorder / Synaptic preotein / Calcium channel / serotonin / dopamine / mood disorder / SNARE / calcium channel / glutamate / ラット / Model Animal / Transgenic Animal / Channelopahty / Transgenome / Sleep / 受容体 / 中枢神経 / Channelopahtv / Transgenone / てんかんモデル / アダプター蛋白複合体 / シナプス小胞形成 / 免疫組織化学 / 海馬 / 興奮性終末 / 抑制性終末 / CA3 / Adaptor protein complex / Synaptic vesicle formation / Hippocampus / Excitatory terminal / Inhibitory terminal / 家族性夜間前頭葉てんかん / てんかん責任遺伝子導入ラット / ニコチン性アセチ / レコリン受容体 / 284Lα4β2-nAChR / 感覚運動皮質 / ニコチン性アセチルコリン受容体 / 284L α4β2-nAChR / autosomal dominant nocturnal frontal-lobe epilepsies / transgenic rat / nicotinic acetylcholine receptor (nAChR) / sleep / sensorimotor cortex / 腎移植レシピエント / アプリケーション・ソフトウェア / 精神状態 / アドヒアランス Less

腎移植レシピエントの精神面を支えるアプリケーション・ソフトウェア開発と効果の検証
- Principal Investigator
  
  田村裕子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Mie University
Pathomechanisms of neuropsychiatric disorders associated with tripartite synaptic transmissionPrincipal Investigator
- Principal Investigator
  
  Okada Motohiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Mie University
Mechanisms of tripartite synaptic transmissionPrincipal Investigator
- Principal Investigator
  
  Okada Motohiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
中枢神経系機能性疾患におけるグリア伝達機能障害病態仮説の構築Principal Investigator
- Principal Investigator
  
  岡田元宏
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
Prevention of neuropsychiatric functional diseasePrincipal Investigator
- Principal Investigator
  
  OKADA Motohiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
Exploring the development of functional disorders in central nervous systemPrincipal Investigator
- Principal Investigator
  
  OKADA Motohiro
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
中枢神経系機能性疾患発症前治療介入の有効性検証Principal Investigator
- Principal Investigator
  
  岡田元宏
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
A Cognitive Neuroscientific Study of a Structural Relation in the Innate Knowledge of Language
- Principal Investigator
  
  AYANO Seiki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Linguistics
- Research Institution
  Mie University
機能性精神疾患の皮質錐体細胞回路障害のtwo hit model仮説の構築
- Principal Investigator
  
  兼子直
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Establishment of animal model harboring a homologous mutation ofhuman epilepsy and analysis of genomics"
- Principal Investigator
  
  UENO Shinya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hirosaki University
Generation of epilepsy model animal bearing a genetic abnormality identified in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) of humanPrincipal Investigator
- Principal Investigator
  
  OKADA Motohiro
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
  Hirosaki University
分子病態を基本とした前頭葉てんかんに対する薬力学的個別化治療の開発Principal Investigator
- Principal Investigator
  
  岡田元宏
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
  Hirosaki University
機能性精神疾患のtwo hiy model仮説の構築
- Principal Investigator
  
  兼子直
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Elucidation of pathomechanisms in region-specific epileptogenesis of autosomal dominant nocturnal frontal lobe epilepsy
- Principal Investigator
  
  HAYAKARI Makoto, 森文秋
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Analysis of molecular biology of epilepsy
- Principal Investigator
  
  KANEKO Sunao
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
リバースゲノミクス的中枢神経系機能性疾患感受性遺伝子検索法の開発Principal Investigator
- Principal Investigator
  
  岡田元宏
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University
Generation and neuro-pharmacological analysis of epilepsy model animals bearing mutations identified in human epilepsy II
- Principal Investigator
  
  MITSUDOME Akihisa
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Fukuoka University
Identification of the responsible genes for childhood epilepsies targeting at channels and receptors expressed in the brain
- Principal Investigator
  
  HIROSE Shinichi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Fukuoka University
Elucidation of mechanisms for spontaneous epileptic seizures in mice lacking μ3B, a subunit of the neuron-specific AP-3B complex
- Principal Investigator
  
  MORI Fumiaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University
Basic mechanisms of transmission in neuronal network
- Principal Investigator
  
  WADA Kazumaru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University
チャネル病の作業仮説に基づく大量高速処理法によるてんかんの責任遺伝子の検索
- Principal Investigator
  
  HIROSE Shinichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Fukuoka University
双極性感情障害とてんかんの共通病態としての異常スウィッチング機構形成機序解明:シナップス蛋白複合体形成-分離過程調整による新たな精神・神経疾患薬物治療開発の試みPrincipal Investigator
- Principal Investigator
  
  岡田元宏
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University
Genetic research of Epilepsy develops to us treatment.
- Principal Investigator
  
  KURIBAYASHI Michito
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University
generation of epilepsy model animals harboring the same genetic defects identified in human epilepsy
- Principal Investigator
  
  HIROSE Shinichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Fukuoka University
多相性神経伝達物質遊離機構の解明と精神神経疾患に対する新たな治療法開発の試みPrincipal Investigator
- Principal Investigator
  
  岡田元宏
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University
細胞間隙内ATP動態が神経伝達物質遊離に与える二相性効果の機序解明Principal Investigator
- Principal Investigator
  
  岡田元宏
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University

[Book] 成人てんかんの薬物療法. In: 辻省次 (Ed.), 最新医学別冊てんかんテキスト2012
- Author(s)
  岡田元宏
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23659564
[Book] 抗てんかん薬の作用機序・薬物動態的特徴. In: 兼子直 (Ed.), てんかん教室改訂第3版2012
- Author(s)
  岡田元宏
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-23659564
[Book] 新薬の作用機序. In: 兼子直(Ed.), てんかんの薬物療法2012
- Author(s)
  岡田元宏
- Publisher
  進行医学出版社
- Data Source
  KAKENHI-PROJECT-23659564
[Book] 疾患モデルの作製と利用　脳・神経疾患2011
- Author(s)
  岡田元宏
- Total Pages
  310
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-23659564
[Book] Novel Treatment of Epilepsy2011
- Author(s)
  Okada, M., Kaneko, S.
- Total Pages
  14
- Publisher
  INTEC
- Data Source
  KAKENHI-PROJECT-22390224
[Book] 疾患モデルの作製と利用脳・神経疾患2011
- Author(s)
  岡田元宏
- Total Pages
  8
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-22390224
[Book] Novel Treatment of Epilepsy2011
- Author(s)
  Okada, M. and Kaneko, S.
- Total Pages
  326
- Publisher
  INTEC
- Data Source
  KAKENHI-PROJECT-23659564
[Book] Chaptor 6 : mechanisms of calcium-associated exocytosis of striatal dopamine and DOPA release, studied by in vivo microdialysis. (Eds by Misu Yoshimi & Goshima Yoshio), pp.89-992005
- Author(s)
  Okada Motohiro, Zhu Gang, Yoshida Shukuko, Hirose Shinichi, Kaneko Sunao
- Total Pages
  350
- Publisher
  Taylor & Francis ; New York
- Data Source
  KAKENHI-PROJECT-16109006
[Book] ニコチン性アセチルコリン受容体のアセチルコリン開口分泌機構に与える効果2004
- Author(s)
  岡田元宏
- Total Pages
  85
- Publisher
  佐藤公道編集「セロトニン:最近の話題(第7回神経伝達物質研究会記録集),Excerpta Medica, Elesevier Japan, K.K.
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Impact of 5-HT7 receptor inverse agonism of lurasidone on monoaminergic tripartite synaptic transmission and pathophysiology of lower risk of weight gain2022
- Author(s)
  Fukuyama Kouji、Motomura Eishi、Shiroyama Takashi、Okada Motohiro
- Journal Title
  
  Biomedicine and Pharmacotherapy
  
  Volume: 148 Pages: 112750-112750
- DOI
  10.1016/j.biopha.2022.112750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] High frequency oscillations play important roles in development of epileptogenesis/ictogenesis via activation of astroglial signallings2022
- Author(s)
  Fukuyama Kouji、Okada Motohiro
- Journal Title
  
  Biomedicine and Pharmacotherapy
  
  Volume: 149 Pages: 112846-112846
- DOI
  10.1016/j.biopha.2022.112846
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Current Limitations and Candidate Potential of 5-HT7 Receptor Antagonism in Psychiatric Pharmacotherapy2021
- Author(s)
  Okubo Ruri、Hasegawa Toshiki、Fukuyama Kouji、Shiroyama Takashi、Okada Motohiro
- Journal Title
  
  Frontiers in Psychiatry
  
  Volume: 12 Pages: 623684-623684
- DOI
  10.3389/fpsyt.2021.623684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin432021
- Author(s)
  Shiroyama Takashi、Fukuyama Kouji、Okada Motohiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Pages: 10013-10013
- DOI
  10.3390/ijms221810013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Can rodent models manifest pathomechanisms of genetic epilepsy?2021
- Author(s)
  Okada Motohiro
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: in press
- DOI
  10.1111/bph.15443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions2021
- Author(s)
  Fukuyama Kouji、Nakano Tomosuke、Shiroyama Takashi、Okada Motohiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Pages: 4122-4122
- DOI
  10.3390/ijms22084122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Effects of Atypical Antipsychotics, Clozapine, Quetiapine and Brexpiprazole on Astroglial Transmission Associated with Connexin432021
- Author(s)
  Fukuyama Kouji、Okada Motohiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Pages: 5623-5623
- DOI
  10.3390/ijms22115623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Brivaracetam prevents astroglial l-glutamate release associated with hemichannel through modulation of synaptic vesicle protein2021
- Author(s)
  Okada Motohiro、Fukuyama Kouji、Shiroyama Takashi、Ueda Yuto
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 138 Pages: 111462-111462
- DOI
  10.1016/j.biopha.2021.111462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Effects of an Atypical Antipsychotic, Zotepine, on Astroglial L-Glutamate Release through Hemichannels: Exploring the Mechanism of Mood-Stabilising Antipsychotic Actions and Antipsychotic-Induced Convulsion2021
- Author(s)
  Fukuyama Kouji、Okada Motohiro
- Journal Title
  
  Pharmaceuticals
  
  Volume: 14 Pages: 1116-1116
- DOI
  10.3390/ph14111116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Upregulated and Hyperactivated Thalamic Connexin 43 Plays Important Roles in Pathomechanisms of Cognitive Impairment and Seizure of Autosomal Dominant Sleep-Related Hypermotor Epilepsy with S284L-Mutant α4 Subunit of Nicotinic ACh Receptor2020
- Author(s)
  Fukuyama Kouji、Fukuzawa Masashi、Okada Motohiro
- Journal Title
  
  Pharmaceuticals
  
  Volume: 13 Pages: 99-99
- DOI
  10.3390/ph13050099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Pathogenesis and pathophysiology of autosomal dominant sleep‐related hypermotor epilepsy with S284L‐mutant α4 subunit of nicotinic ACh receptor2020
- Author(s)
  Fukuyama Kouji、Fukuzawa Masashi、Shiroyama Takashi、Okada Motohiro
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: -
- DOI
  10.1111/bph.14974
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Effects of Carbamazepine, Lacosamide and Zonisamide on Gliotransmitter Release Associated with Activated Astroglial Hemichannels2020
- Author(s)
  Fukuyama Kouji、Ueda Yuto、Okada Motohiro
- Journal Title
  
  Pharmaceuticals
  
  Volume: 13 Pages: 117-117
- DOI
  10.3390/ph13060117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Age-Dependent and Sleep/Seizure-Induced Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy2020
- Author(s)
  Fukuyama Kouji、Okada Motohiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Pages: 8142-8142
- DOI
  10.3390/ijms21218142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Astroglial Connexin43 as a Potential Target for a Mood Stabiliser2020
- Author(s)
  Okada Motohiro、Oka Tomoka、Nakamoto Misaki、Fukuyama Kouji、Shiroyama Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Pages: 339-339
- DOI
  10.3390/ijms22010339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Pathomechanism of nocturnal paroxysmal dystonia in autosomal dominant sleep-related hypermotor epilepsy with S284L-mutant α4 subunit of nicotinic ACh receptor2020
- Author(s)
  Fukuyama Kouji、Fukuzawa Masashi、Shiroyama Takashi、Okada Motohiro
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 126 Pages: 110070-110070
- DOI
  10.1016/j.biopha.2020.110070
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] A Working Hypothesis Regarding Identical Pathomechanisms between Clinical Efficacy and Adverse Reaction of Clozapine via the Activation of Connexin432020
- Author(s)
  Okada Motohiro、Fukuyama Kouji、Shiroyama Takashi、Murata Masahiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Pages: 7019-7019
- DOI
  10.3390/ijms21197019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Interaction between Mesocortical and Mesothalamic Catecholaminergic Transmissions Associated with NMDA Receptor in the Locus Coeruleus2020
- Author(s)
  Okada Motohiro、Fukuyama Kouji
- Journal Title
  
  Biomolecules
  
  Volume: 10 Pages: 990-990
- DOI
  10.3390/biom10070990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Upregulated Connexin 43 Induced by Loss-of-Functional S284L-Mutant α4 Subunit of Nicotinic ACh Receptor Contributes to Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy2020
- Author(s)
  Fukuyama Kouji、Fukuzawa Masashi、Okubo Ruri、Okada Motohiro
- Journal Title
  
  Pharmaceuticals
  
  Volume: 13 Pages: 58-58
- DOI
  10.3390/ph13040058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Candidate Strategies for Development of a Rapid-Acting Antidepressant Class That Does Not Result in Neuropsychiatric Adverse Effects: Prevention of Ketamine-Induced Neuropsychiatric Adverse Reactions2020
- Author(s)
  Okada Motohiro、Kawano Yasuhiro、Fukuyama Kouji、Motomura Eishi、Shiroyama Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Pages: 7951-7951
- DOI
  10.3390/ijms21217951
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Activation of Astroglial Connexin Is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine2020
- Author(s)
  Fukuyama Kouji、Okubo Ruri、Murata Masahiko、Shiroyama Takashi、Okada Motohiro
- Journal Title
  
  Cells
  
  Volume: 9 Pages: 414-414
- DOI
  10.3390/cells9020414
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Lurasidone Sub-Chronically Activates Serotonergic Transmission via Desensitization of 5-HT1A and 5-HT7 Receptors in Dorsal Raphe Nucleus2019
- Author(s)
  Okada、Fukuyama、Okubo、Shiroyama、Ueda
- Journal Title
  
  Pharmaceuticals
  
  Volume: 12 Pages: 149-149
- DOI
  10.3390/ph12040149
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Can Financial Support Reduce Suicide Mortality Rates?2019
- Author(s)
  Kato Ryo、Okada Motohiro
- Journal Title
  
  International Journal of Environmental Research and Public Health
  
  Volume: 16 Pages: 4797-4797
- DOI
  10.3390/ijerph16234797
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Effects of acute and sub-chronic administrations of guanfacine on catecholaminergic transmissions in the orbitofrontal cortex2019
- Author(s)
  Okada Motohiro、Fukuyama Kouji、Kawano Yasuhiro、Shiroyama Takashi、Suzuki Dai、Ueda Yuto
- Journal Title
  
  Neuropharmacology
  
  Volume: 印刷中
- DOI
  10.1016/j.neuropharm.2019.02.029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04892
[Journal Article] Lurasidone inhibits NMDA receptor antagonist‐induced functional abnormality of thalamocortical glutamatergic transmission via 5‐HT 7 receptor blockade2019
- Author(s)
  Okada Motohiro、Fukuyama Kouji、Ueda Yuto
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 176 Pages: 4002-4018
- DOI
  10.1111/bph.14804
- Data Source
  KAKENHI-PROJECT-19K08073
[Journal Article] Effects of levetiracetam on astroglial release of kynurenine-pathway metabolites2018
- Author(s)
  Fukuyama Kouji、Okada Motohiro
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 175 Pages: 4253-4265
- DOI
  10.1111/bph.14491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04892
[Journal Article] Cystine/Glutamate Antiporter and Aripiprazole Compensate NMDA Antagonist-Induced Dysfunction of Thalamocortical L-Glutamatergic Transmission2018
- Author(s)
  Fukuyama Kouji、Hasegawa Toshiki、Okada Motohiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Pages: 3645-3645
- DOI
  10.3390/ijms19113645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04892
[Journal Article] Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium?2017
- Author(s)
  Mizuno S, Takeuchi S, Kishiwada M, Mizutani N, Matsuda M, Sekoguchi N, Iizawa Y, Azumi Y, Kuriyama N, Usui M, Sakurai H, Maruyama K, Okuda M, Okada M, Isaji S.
- Journal Title
  
  Digestive Surgery
  
  Volume: -
- DOI
  10.1159/000456627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04892, KAKENHI-PROJECT-26460196
[Journal Article] Auditory change-related cerebral responses and personality traits.2016
- Author(s)
  Tanahashi M, Motomura E, Inui K, Ohoyama K, Tanii H, Konishi Y, Shiroyama T, Nishihara M, Kakigi R, Okada M.
- Journal Title
  
  Neurosci Res
  
  Volume: 103 Pages: 34-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04892
[Journal Article] Pre-operative Assessment of Psychological Characteristics and Mood States in Living Donor Kidney and Liver Transplantation.2016
- Author(s)
  Nishikawa K, Hasegawa T, Usami A, Urawa A, Watanabe S, Mizuno S, Isaji S, Sugimura Y, Okada M.
- Journal Title
  
  Transplant Proc.
  
  Volume: 48 Pages: 1018-1021
- DOI
  10.1016/j.transproceed.2015.12.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04892
[Journal Article] Spontaneous epileptic seizures in transgenic rats harboring a human ADNFLE missense mutation in the β2-subunit of the nicotinic acetylcholine receptor.2016
- Author(s)
  Yuko Shiba, Fumiaki Mori, Junko Yamada, Keisuke Migita, Yoshikazu Nikaido, Koichi Wakabayashi, Sunao Kaneko, Motohiro Okada, Shinichi Hirose, Shinya Ueno
- Journal Title
  
  Neurosci Res.
  
  Volume: 100 Pages: 46-54
- DOI
  10.1016/j.neures.2015.06.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10503, KAKENHI-PROJECT-26460314, KAKENHI-PROJECT-26460693, KAKENHI-PROJECT-15H04892
[Journal Article] Dysfunction of ventrolateral prefrontal cortex underlying social anxiety disorder: A multi-channel NIRS study.2015
- Author(s)
  Yokoyama C, Kaiya H, Kumano H, Kinou M, Umekage T, Yasuda S, Takei K, Nishikawa, M, Sasaki T, Nishimura Y, Hara N, Inoue K, Kaneko Y, Suzuki S, Tanii H, Okada M, Okazaki Y
- Journal Title
  
  Neuroimage Clin.
  
  Volume: 8 Pages: 455-461
- DOI
  10.1016/j.nicl.2015.05.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591679, KAKENHI-PROJECT-15H04892, KAKENHI-PROJECT-24500452
[Journal Article] 1. Gene×gene×gender interaction of BDNF and COMT genotypes associated with panic disorder2014
- Author(s)
  Konishi, Y., Tanii, H., Otowa, T., Sasaki, T., Tochigi, M., Umekage, T., Motomura, E., Shiroyama, T., Kaiya, H., Okazaki, Y., Okada, M.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry.
  
  Volume: 51C Pages: 119-125
- DOI
  10.1016/j.pnpbp.2014.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-24591679
[Journal Article] Zonisamide regulates basal ganglia transmission via astroglial kynurenine pathway.2014
- Author(s)
  Fukuyama, K., Tanahashi, S., Hoshikawa, M., Shinagawa, R., Okada, M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 76 Pt A Pages: 137-145
- DOI
  10.1016/j.neuropharm.2013.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Association of nonsense mutation in GABRG2 with abnormal trafficking of GABAA receptors in severe epilepsy.2014
- Author(s)
  Ishii, A., Kanaumi, T., Sohda, M., Misumi, Y., Zhang, B., Kakinuma, N., Haga, Y., Watanabe, K., Takeda, S., Okada, M., Ueno, S., Kaneko, S., Takashima, S., Hirose, S.
- Journal Title
  
  Epilepsy research
  
  Volume: 108 Pages: 420-32
- DOI
  10.1016/j.eplepsyres.2013.12.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23570149, KAKENHI-PROJECT-23590699, KAKENHI-PROJECT-23791201, KAKENHI-PROJECT-24249060, KAKENHI-PROJECT-24520009, KAKENHI-PUBLICLY-25129708, KAKENHI-PROJECT-25670481, KAKENHI-PROJECT-26460664
[Journal Article] ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation2013
- Author(s)
  Yamamura, S., Hoshikawa, M., Kato, D., Saito, H., Suzuki, N., Niwa, O., Okada, M.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 168 Pages: 1088-1100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Differential mechanisms underlie the regulation of serotonergic transmission in the dorsal and median raphe nuclei by mirtazapine: a dual probe microdialysis study2013
- Author(s)
  Fukuyama, K., Tanahashi, T., Hamaguchi, T., Nakagawa, M., Shiroyama, T., Motomura, E., Okada, M
- Journal Title
  
  Psychopharmacology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] A novel prophylactic effect of furosemide treatment on autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)2013
- Author(s)
  Yamada J, Zhu G, Okada M, Hirose S,
- Journal Title
  
  Epilepsy research.
  
  Volume: 107 Pages: 127-137
- DOI
  10.1016/j.eplepsyres.2013.08.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23590276, KAKENHI-PROJECT-24249060, KAKENHI-PROJECT-24790336, KAKENHI-PUBLICLY-25129708, KAKENHI-PROJECT-25670481, KAKENHI-PROJECT-23590706
[Journal Article] ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation2013
- Author(s)
  Yamamura, S., Hoshikawa, M., Kato, D., Saito, H., Suzuki, N., Niwa, O., Okada, M.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 168 Pages: 1088-1100
- DOI
  10.1111/j.1476-5381.2012.02132.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Differential mechanisms underlie the regulation of serotonergic transmission in the dorsal and median raphe nuclei by mirtazapine : a dual probe microdialysis study2013
- Author(s)
  Fukuyama, K., Tanahashi, S., Hamaguchi, T., Nakagawa, M., Shiroyama, T., Motomura, E., Okada, M.
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 229 Pages: 617-626
- DOI
  10.1007/s00213-013-3122-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Clozapine, but not haloperidol, enhances glial D-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes.2012
- Author(s)
  Tanahashi, S., Yamamura, S., Nakagawa, M., Motomura, E., Okada, M.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 165 Pages: 1543-1555
- DOI
  10.1111/j.1476-5381.2011.01638.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23659564
[Journal Article] Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Abeta generation in Alzheimer's disease2012
- Author(s)
  Saito, Y., Inoue, T., Zhu, G., Kimura, N., Okada, M., Nishimura, M., Kimura, N., Murayama, S., Kaneko, S., Shigemoto, R., Imoto, K., Suzuki, T
- Journal Title
  
  Mol Neurodegeneration
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Hyperpolarization-activated cyclic nucleotide gated channels : a potential molecular link between epileptic seizures and Abeta generation in Alzheimer's disease2012
- Author(s)
  Fukuyama, K., Tanahashi, S., Nakagawa, M., Yamamura, S., Motomura, E., Shiroyama, T., Tanii, H., Okada, M.
- Journal Title
  
  Mol Neurodegeneration
  
  Volume: 518 Pages: 69-74
- DOI
  10.1016/j.neulet.2012.03.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Dysfunction of extrasynaptic GABAergic transmission in phospholipase C-related, but catalytically inactive protein 1 knockout mice is associated with an epilepsy phenotype2012
- Author(s)
  Zhu, G., Yoshida, S., Migita, K., Yamada, J., Mori, F., Tomiyama, M., Wakabayashi,K., Kanematsu, T., Hirata, M., Kaneko, S., Ueno, S., Okada, M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 340 Pages: 520-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Novel δ1-receptor agonist KNT-127 increases the release of dopamine and 1-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex2012
- Author(s)
  Tanahashi S, Ueda Y, Nakajima A, Yamamura S, Nagase H, Okada M
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 2057-2067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] emory-based pre-attentive auditory N1 elicited by sound movement.2012
- Author(s)
  Ohoyama, K., Motomura, E., Inui, K., Nishihara, M., Otsuru, N., Oi, M., Kakigi, R., Okada, M.
- Journal Title
  
  Neurosci Res
  
  Volume: 73 Pages: 248-251
- DOI
  10.1016/j.neures.2012.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23659564
[Journal Article] Electroencephalographic dipole source modeling of frontal intermittent rhythmic delta activity2012
- Author(s)
  Motomura, E., Inui, K., Ohoyama, K., Nishimura, Y., Nakagawa, M., Maeda, M., Matsushima, N., Ushiro, K., Suzuki, D., Kakigi, R., Okada, M
- Journal Title
  
  Neuropsychobiology
  
  Volume: 65 Pages: 103-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Effect of lamotrigine and carbamazepine on corticotropin-releasing factor-associated serotonergic transmission in rat dorsal raphe nucleus2012
- Author(s)
  Tanahashi, S., Yamamura, S., Nakagawa, M., Motomura, E., Okada, M
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 220 Pages: 599-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission2012
- Author(s)
  Tanahashi, S., Yamamura, S., Nakagawa, M., Motomura, E., Okada, M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 765-774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] The development of agoraphobia is associated with the symptoms and location of a patient's first panic attack2012
- Author(s)
  Hara, N., Nishimura, Y., Yokoyama, C., Inoue, K., Nishida, A., Tanii, H., Okada, M., Kaiya, H., Okazaki, Y.
- Journal Title
  
  Biopsychosoc Med
  
  Volume: 6 Pages: 12-12
- DOI
  10.1186/1751-0759-6-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Combination Therapy of Zonisamide With Aripiprazole on ECTand Benzodiazepine-Resistant Periodic Catatonia2012
- Author(s)
  Nakagawa, M., Yamamura, S., Motomura, E., Tanii, H., Okada, M
- Journal Title
  
  J Neuropsychiatry Clin Neurosci
  
  Volume: 24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Dysfunction of extrasynaptic GABAergic transmission in phospholipase C-related, but catalytically inactive protein 1 knockout mice is associated with an epilepsy phenotype.2012
- Author(s)
  Tanahashi S, Okada M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 340 Pages: 520-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Clozapine, but not haloperidol, enhances glial d-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes2012
- Author(s)
  Tanahashi S, Yamamura S, Nakagawa M, Motomura E, Okada M
- Journal Title
  
  Br J Pharmacol
  
  Volume: 165 Pages: 1543-1555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Effect of lamotrigine and carbamazepine on corticotropin-releasing factor-associated serotonergic transmission in rat dorsal raphe nucleus.2012
- Author(s)
  Tanahashi, S., Yamamura, S., Nakagawa, M., Motomura, E., Okada, M.
- Journal Title
  
  Psychopharmacology
  
  Volume: 220 Pages: 599-610
- DOI
  10.1007/s00213-011-2506-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23659564
[Journal Article] Electroencephalographic dipole source modeling of frontal intermittent rhythmic delta activity2012
- Author(s)
  Motomura, E., Inui, K., Ohoyama, K., Nishimura, Y., Nakagawa, M., Maeda, M., Matsushima, N., Ushiro, K., Suzuki, D., Kakigi, R., Okada, M.
- Journal Title
  
  Neuropsychobiology
  
  Volume: 65 Pages: 103-108
- DOI
  10.1159/000330011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Dysfunction of extrasynaptic GABAergic transmission in phospholipase C-related, but catalytically inactive protein 1 knockout mice is associated with an epilepsy phenotype2012
- Author(s)
  Zhu G., Yoshida S., Migita K., Yamada J., Ueno S
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 340(3) Pages: 520-528
- DOI
  10.1124/jpet.111.182386
- URL
  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22128345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590229, KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23590276, KAKENHI-PROJECT-23659564, KAKENHI-PROJECT-23659735
[Journal Article] The development of agoraphobia is associated with the symptoms and location of a patient's first panic attack2012
- Author(s)
  Hara, N., Nishimura, Y., Yokoyama, C., Inoue, K., Nishida, A., Tanii, H., Okada, M., Kaiya, H., Okazaki, Y.
- Journal Title
  
  Biopsychosoc Med
  
  Volume: 6 Pages: 12-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Memory-based pre-attentive auditory N1 elicited by sound movement2012
- Author(s)
  Ohoyama, K., Motomura, E., Inui, K., Nishihara, M., Otsuru, N., Oi, M., Kakigi, R., Okada, M
- Journal Title
  
  Neurosci Res
  
  Volume: 73 Pages: 248-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Novel δ1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex.2012
- Author(s)
  Tanahashi, S., Ueda, Y., Nakajima, A., Yamamura, S., Nagase, H., Okada, M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 2057-2067
- DOI
  10.1016/j.neuropharm.2012.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23659564
[Journal Article] Novel δ1-receptor agonist KNT-127 increases the release of dopamine and l-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex.2012
- Author(s)
  Tanahashi S, Okada M
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 2057-2067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Different actions for acute and chronic administration of mirtazapine on serotonergic transmission associated with raphe nuclei and their innervation cortical regions.2012
- Author(s)
  Yamamura S, Okada M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 550-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Combination Therapy of Zonisamide With Aripiprazole on ECT- and Benzodiazepine-Resistant Periodic Catatonia2012
- Author(s)
  Motomura, E., Tanii, H., Usami, A., Ohoyama, K., Nakagawa, M., Okada, M.
- Journal Title
  
  J Neuropsychiatry Clin Neurosci
  
  Volume: 24 Pages: 38-39
- DOI
  10.1176/appi.neuropsych.11040093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23659564
[Journal Article] Levetiracetam inhibits neurotransmitter release associated with CICR2012
- Author(s)
  Fukuyama, K., Tanahashi, S., Nakagawa, M., Yamamura, S., Motomura, E., Shiroyama, T., Tanii, H., Okada, M
- Journal Title
  
  Neurosci Lett
  
  Volume: 518 Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Lamotrigine-induced neuroleptic malignant syndrome under risperidone treatment: a case report2012
- Author(s)
  Motomura, E., Tanii, H., Usami, A., Ohoyama, K., Nakagawa, M., Okada, M.
- Journal Title
  
  J Neuropsychiatry Clin Neurosci
  
  Volume: 24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission.2012
- Author(s)
  Tanahashi, S., Yamamura, S., Nakagawa, M., Motomura, E., Okada, M
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 765-774
- DOI
  10.1016/j.neuropharm.2011.08.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23659564
[Journal Article] Novel delta1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex2012
- Author(s)
  Tanahashi, S., Ueda, Y., Nakajima, A., Yamamura, S., Nagase, H., Okada, M
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 2057-2067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Neuroleptic malignant syndrome induced by blonanserin.2011
- Author(s)
  Ohoyama K, Okada M.
- Journal Title
  
  J Neuropsychiatry Clin Neurosci.
  
  Volume: 23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Different actions for acute and chronic administration of mirtazapine on serotonergic transmission associated with raphe nuclei and their innervation cortical regions2011
- Author(s)
  Yamamura, S., Abe, M., Nakagawa, M., Ochi, S., Ueno, S., Okada, M
- Journal Title
  
  Neuropharmacology
  
  Volume: 60 Pages: 550-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex2011
- Author(s)
  Ohoyama, K., Yamamura, S., Hamaguchi, T., Nakagawa, M., Motomura, E., Shiroyama, T., Tanii, H., Okada, M.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 653 Pages: 47-57
- DOI
  10.1016/j.ejphar.2010.11.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Different actions for acute and chronic administration of mirtazapine on serotonergic transmission associated with raphe nuclei and their innervation cortical regions2011
- Author(s)
  Yamamura S, Abe M, Nakagawa M, Ochi S, Ueno S, Okada M
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Pages: 550-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Neuroleptic malignant syndrome induced by blonanserin2011
- Author(s)
  Ohoyama K, Tanii H, Motomura E, Konishi Y, Nakagawa M, Matsumoto T, Shiroyama T, Okada M
- Journal Title
  
  J Neuropsychiatry Clin Neurosci
  
  Volume: 23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex2011
- Author(s)
  Ohoyama, K., Yamamura, S., Hamaguchi, T., Nakagawa, M., Motomura, E., Shiroyama, T., Tanii, H., Okada, M.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 653 Pages: 47-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659564
[Journal Article] Different actions for acute and chronic administration of mirtazapine on serotonergic transmission associated with raphe nuclei and their innervation cortical regions2011
- Author(s)
  Yamamura, S., Abe, M., Nakagawa, M., Ochi, S., Ueno, S., Okada, M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 60 Pages: 550-560
- DOI
  10.1016/j.neuropharm.2010.12.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Validation criteria for genetic animal models of epilepsy2010
- Author(s)
  Okada M, et al
- Journal Title
  
  Epilepsy & Seizure
  
  Volume: 3 Pages: 109-120
- NAID
  130000255297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659276
[Journal Article] An event-related fNIRS investigation of Japanese word order2010
- Author(s)
  Nishimura Y, Sugisaki K, Hattori N, Inokuchi Y, Komachi M, Ogawa M, Okada M, Okazaki Y, Taki W, Yamamoto T, Yoshida E, Ayano S
- Journal Title
  
  Exp Brain Res. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Generation of epilepsy animal model bearing a genetic abnormality identified in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) of humans2010
- Author(s)
  Okada M
- Journal Title
  
  Jpn.J.Neuropsychopharmacol.
  
  Volume: 30 Pages: 9-14
- NAID
  10029093096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659276
[Journal Article] An Event-Related fNIRS Investigation of Japanese Word Order2010
- Author(s)
  Nishimura, Y., K.Sugisaki, N.Hattori, Y.Inokuchi, M.Komachi, Y.Nishimura, M.Ogawa, M.Okada, Y.Okazaki, W.Taki, T.Yamamoto, E.Yoshida, S.Ayano.
- Journal Title
  
  Experimental Brain Research 202(1).
  
  Pages: 239-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Validation criteria for genetic animal models of epilepsy.2010
- Author(s)
  Okada, M., G.Zhu, S.Yoshida, S.Kaneko.
- Journal Title
  
  Epilepsy, Seizure 3.
  
  Pages: 109-120
- NAID
  130000255297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Validation criteria for genetic animal models of epilepsy2010
- Author(s)
  Okada M, et al
- Journal Title
  
  Epilepsy & Seizure
  
  Volume: 3 Pages: 109-120
- NAID
  130000255297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Generation of epilepsy animal model bearing a genetic abnormality identified in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) of humans. Jpn. J2010
- Author(s)
  Okada, M.
- Journal Title
  
  Neuropsychopharmacol
  
  Volume: 30 Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] An Event-Related fNIRS Investigation of Japanese Word Order2010
- Author(s)
  Nishimura, Y., K.Sugisaki, N.Hattori, Y.Inokuchi, M.Komachi, Y.Nishimura, M.Ogawa, M.Okada, Y.Okazaki, W.Taki, T.Yamamoto, E.Yoshida, S.Ayano
- Journal Title
  
  Experimental Brain Research
  
  Volume: 202(1) Pages: 239-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Generation of epilepsy animal model bearing a genetic abnormality identified in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) of humans2010
- Author(s)
  Okada M
- Journal Title
  
  Jpn.J.Neuropsychopharmacol.
  
  Volume: 30 Pages: 9-14
- NAID
  10029093096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390224
[Journal Article] Specific panic attack symptoms in panic disorder patients with putative genetic factor2009
- Author(s)
  Nishimura Y, Tanii H, Hara N, Inoue K, Nishida A, Okada M, Kaiya H, Okazaki Y
- Journal Title
  
  Psychiatry Clin Neurosci 63
  
  Pages: 251-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Zonisamide enhances delta receptor-associated neurotransmitter release in striato-pallidal pathway2009
- Author(s)
  Yamamura, S., Ohoyama, K., Naease, H., Okada, M.
- Journal Title
  
  Neuropharmacology 57
  
  Pages: 322-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Intrasubject reproducibility of prefrontal cortex activities during a verbal fluency task over two repeated sessions using multi-channel near-infrared spectroscopy2009
- Author(s)
  Kakimoto Y, Nishimura Y, Hara N, Okada M, Tanii H, Okazaki Y
- Journal Title
  
  Psychiatry Clin Neurosci 63
  
  Pages: 491-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Lack of potassium current in W309R mutant KCNQ3 channel causing benign familial neonatal convulsions (BFNC).2009
- Author(s)
  Sugiura Y, Nakatsu F, Hiroyasu K, Ishii A, Hirose S, Okada M, Jibiki I, Ohno H, Kaneko S, Ugawa Y.
- Journal Title
  
  Epilepsy Res 83(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex2009
- Author(s)
  Yamamura S, Ohoyama K, Hamaguchi T, Nakagawa M, Suzuki D, Matsumoto T, Motomura E, Tanii H, Shiroyama T, Okada M
- Journal Title
  
  Br J Pharmacol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Lack of potassium current in W309R mutant KCNQ3 channel causing benign familial neonatal convulsions (BFNC)2009
- Author(s)
  Sugiura Y, Nakatsu F, Hiroyasu K, Ishii A, Hirose S, Okada M, Jibiki I, Ohno H, Kaneko S, Ugawa Y
- Journal Title
  
  Epilepsy Res 84
  
  Pages: 82-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin.2009
- Author(s)
  Yamamura, S., Hamaguchi, T., Ohoyama, K., Sugiura, Y., Suzuki, D., Kanehara, S., Nakagawa, M., Motomura, E., Matsumoto, T., Tanii, H., Shiroyama, T., Okada, M.
- Journal Title
  
  Epilepsy Res 84
  
  Pages: 172-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of zonisamide on neurotransmitter release associated with inositol triphosphate receptors2009
- Author(s)
  Yamamura S, Saito. H, Suzuki N, kashimoto S, Hamaguchi H, Ohoyama K, Suzuki D, Kanehara S, Nakagawa M, Shiroyama T, Okada M.
- Journal Title
  
  Neurosci Lett (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] A de novo KCNQ2 mutation detected in non-familial benign neonatal convulsions2009
- Author(s)
  Ishii A, Fukuma G, Uehara. A, Miyajima T, Makita Y, Hamachi A, Yasukochi M, Inoue T, Yasumoto S, Okada M, Kaneko S, Mitsudome A, Hirose S.
- Journal Title
  
  Brain Dev 31(1)
  
  Pages: 27-33
- NAID
  10025578186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Effects of quetiapine on monoamine, GABA, and glutamate release in rat prefrontal cortex.2009
- Author(s)
  Yamamura, S., Ohoyama, K., Hamaguchi, T., Kashimoto, K., Nakagawa, M., Kanehara, S., Suzuki, D., Matsumoto, T., Motomura, E., Shiroyama, T., Okada, M.
- Journal Title
  
  Psychopharmacology (Berl) 206
  
  Pages: 243-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of quetiapine on monoamine, GABA, and glutamate release in rat prefrontal cortex2009
- Author(s)
  Yamamura S, Ohoyama K, Hamaguchi T, Kashimoto K, Nakagawa M, Kanehara S, Suzuki D, Matsumoto T, Motomura E, Shiroyama T, Okada M
- Journal Title
  
  Psychopharmacology 206
  
  Pages: 243-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Specific panic attack symptoms in panic disorder patients with putative genetic factor.2009
- Author(s)
  Nishimura Y, Tanii H, Hara N, Inoue K, Nishida A, Okada M, Kaiva H, Okazaki Y.
- Journal Title
  
  Psychiatr Clin Neurosci. 63(2)
  
  Pages: 251-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin2009
- Author(s)
  Yamamura S, Hamaguchi T, Ohoyama K, Sugiura Y, Suzuki D, Kanehara S, Nakagawa M, Motomura E, Matsumoto T, Tanii H, Shiroyama T, Okada. M.
- Journal Title
  
  Epilepsy Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] A de novo KCNQ2 mutation detected in non-familial benign neonatal convulsions2009
- Author(s)
  Ishii A, Fukuma G, Uehara A, Miyajima T, Makita Y, Hamachi A, Yasukochi M, Inoue T, Yasumoto S, Okada M, Kaneko S, Mitsudome A, Hirose S
- Journal Title
  
  Brain Dev 31
  
  Pages: 27-33
- NAID
  10025578186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of zonisamide on neurotransmitter release associated with inositol triphosphate receptors2009
- Author(s)
  Yamamura S, Saito H, Suzuki N, Kashimoto S, Hamaguchi T, Ohoyama K, Suzuki D, Kanehara S, Nakagawa M, Shiroyama T, Okada M
- Journal Title
  
  Neurosci Lett 454
  
  Pages: 91-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] A de novo KCNQ2 mutation detected in non-familial benign neonatal convulsions.2009
- Author(s)
  Ishii A, Fukuma G, Uehara A Miyajima T, Makita Y, Hamachi A, Yasukochi M, Inoue T, Yasumoto S, Okada M, Kaneko S, Mitsudome A, Hirose S.
- Journal Title
  
  Brain Dev 31
  
  Pages: 27-33
- NAID
  10025578186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Relationship between the prefrontal function during a cognitive task and the severity of the symptoms in patients with panic disorder : a multi-channel NIRS study.2009
- Author(s)
  Nishimura, Y, H.Tanii, N.Hara, K.Inoue, H.Kaiya, A.Nishida, M.Okada, Y.Okazaki.
- Journal Title
  
  Psychiatry Res : Neuroimaging. 172(2)
  
  Pages: 168-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex2009
- Author(s)
  Yamamura S, Ohoyama K, Hamaguchi T, Nakagawa M, Suzuki D, Matsumoto T, Motomura E, Tanii H, Shiroyama T, Okada M
- Journal Title
  
  Br J Pharmacol 157
  
  Pages: 656-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Zonisamide enhances delta receptor-associated neurotransmitter release in striato-pallidal pathway.2009
- Author(s)
  Yamamura, S., Ohoyama, K., Nagase, H., Okada, M.
- Journal Title
  
  Neuropharmacology 57
  
  Pages: 322-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Asymmetry of prefrontal cortex activities and catechol-O-methyltransferase Val158Met genotype in patients with panic disorder during a verbal fluency task : near-infrared spectroscopy study2009
- Author(s)
  Tanii H, Nishimura Y, Inoue K, Koshimizu H, Matsumoto R, Takami T, Hara N, Nishida A, Okada M, Kaiya H, Okazaki Y
- Journal Title
  
  Neurosci Lett 452
  
  Pages: 63-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] An Event-Related fNIRS Investigation of Japanese Word Order2009
- Author(s)
  Nishimura, Y., K.Sugisaki, N.Hattori, Y.Inokuchi, M.Komachi, Y.Nishimura, M.Ogawa, M.Okada, Y.Okazaki, W.Taki, T.Yamamoto, E.Yoshida, S.Ayano
- Journal Title
  
  Experimental Brain Research 202
  
  Pages: 239-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin2009
- Author(s)
  Yamamura S, Hamaguchi T, Ohoyama K, Sugiura Y, Suzuki D, Kanehara S, Nakagawa M, Motomura E, Matsumoto T, Tanii H, Shiroyama T, Okada M
- Journal Title
  
  Epilepsy Res 83(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex2009
- Author(s)
  Yamamura S, Hamaguchi T, Ohoyama K, Sugiura Y, Suzuki D, Kanehara S, Nakagawa M, Motomura E, Matsumoto T, Tanii H, Shiroyama T, Okada M
- Journal Title
  
  British Journal of Pharmacology 156(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Lack of potassium current in W309R mutant KCNQ3 channel causing benign familial neonatal convulsions (BFNC)2009
- Author(s)
  Sugiura Y, Nakatsu F, Hiroyasu K, Ishii A, Hirose S, Okada M, Jibiki I, Ohno H, Kaneko S, Ugawa Y.
- Journal Title
  
  Epilepsy Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Lack of potassium current in W309R mutant KCNQ3 channel causing benign familial neonatal convulsions (BFNC)2009
- Author(s)
  Sugiura Y, Nakatsu F, Hiroyasu K, Ishii A, Hirose S, Okada M, Jibiki I, Ohno H, Kaneko S, Ugawa Y.
- Journal Title
  
  EpilepsyRes 84(1)
  
  Pages: 82-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Relationship between the prefrontal function during a cognitive task and the severity of the symptoms in patients with panic disorder : a multi-channel NIRS study2009
- Author(s)
  Nishimura Y, Tanii H, Hara N, Inoue K, Kaiya H, Nishida A, Okada M, Okazaki Y
- Journal Title
  
  Psychiatry Res 172
  
  Pages: 168-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Intrasubject Reproducibility of Prefrontal Cortex Activities during a Verbal Fluency Task over Two Repeated Sessions Using Multi-Channel Near-Infrared Spectroscopy2009
- Author(s)
  Kakimoto, Y, Y.Nishimura, N.Hara, M.Okada, H.Tanii, Y.Okazaki
- Journal Title
  
  Psychiatry and Clinical Neurosciences 63(4)
  
  Pages: 491-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex.2009
- Author(s)
  Yamamura, S., Ohoyama, K., Hamaguchi, T., Nakagawa, M., Suzuki, D., Matsumoto, T., Motomura, E., Tanii, H., Shiroyama, T., Okada, M.
- Journal Title
  
  Br J Pharmacol 157
  
  Pages: 656-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Knockdown of Cav2.1 calcium channels is sufficient to induce neurological disorders observed in natural occurring Cacnala mutants in mice2009
- Author(s)
  Saito H, Okada M, Miki T, Wakamori M, Futatsugi A, Mori Y, Mikoshiba K, Suzuki N
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 1029-1033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin2009
- Author(s)
  Yamamura S, Hamaguchi T, Ohoyama K, Sugiura Y, Suzuki D, Kanehara S, Nakagawa M, Motomura E, Matsumoto T, Tanii H, Shiroyama T, Okada M
- Journal Title
  
  Epilepsy Res 84
  
  Pages: 172-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of zonisamide on neurotransmitter release associated with inositol triphosphate receptors.2009
- Author(s)
  Yamamura, S., Saito, H., Suzuki, N., Kashimoto, S., Hamaguchi, T., Ohoyama, K., Suzuki, D., Kanehara, S., Nakagawa, M., Shiroyama, T., Okada, M.
- Journal Title
  
  Neurosci Lett 454
  
  Pages: 91-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.2008
- Author(s)
  Zhu, G., Okada, M., Yoshida, S., Ueno, S., Mori, F., Takahara, T., Saito, R., Miura, Y., Kishi, A., Tomiyama, M., Sato, A., Kojima, T., Fukuma, G., Wakabayashi, K., Hase, K., Ohno, H., Kijima, H., Takano, Y., Mitsudome, A., Kaneko, S., Hirose, S.
- Journal Title
  
  J Neurosci 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Associations between psychotic-like experiences and mental health status and other psychopathologies among Japanese early teens.2008
- Author(s)
  Nishida A, Tanii H, Nishimura Y, Kajiki N, Inoue K, Okada M, Sasaki T, Okazaki Y.
- Journal Title
  
  Schizophr Res (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Population estimation of the effects of cytochrome P450 2C19 and 3A5 polymorphisms on zonisamide clearance2008
- Author(s)
  Okada Y, Seo T, Wanibuchi A, Hashimoto N, Higa Y, Ishitsu T, Nakagawa K.
- Journal Title
  
  Ther Drug Monit 30
  
  Pages: 540-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, Mori F, Takahata T, Saito R, Miura Y, Kishi A, Tomiyama M, Sato A, Kojima T, Fukuma G, Wakabayashi K, Hase K, Ohno H,Kijima H, Takano Y, Mitsudome A,Kaneko S, Hirose S.
- Journal Title
  
  J Neurosci 28(47)
  
  Pages: 12465-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Rats Harboring S284L Chrna4 Mutation Show Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal Lobe Epilepsy Phenotype2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, Mori F, Takahara T, Saito R, Miura Y, Kishi A, Tomiyama M, Sato A, Kojima T, Fukuma G, Wakabayashi K, Hase K, Ohno H, Kijima H, Ta kano Y, Mitsudome A, Kaneko S & Hirose S.
- Journal Title
  
  Journal of Neuroscience 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] Associations between psychotic-like experiences and mental health status and other psychopathologies among Japanese early teens2008
- Author(s)
  Nishida A, Tanii H, Nishimura Y, Kajiki N, Inoue K, Okada M, Sasaki T, Okazaki Y.
- Journal Title
  
  Schizophr Res 99
  
  Pages: 125-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Rats Harboring S284L Chrna4 MutationShow Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal LobeEpilepsy Phenotyp J2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, MoriF, Takahara T, Saito R, Miura Y, Kishi A,Tomiyama M, Sato A, Kojima T, Fukuma G,Wakabayashi K, Hase K, Ohno H, Kijima H, Takano Y, Mitsudome A, Kaneko S & Hirose S.
- Journal Title
  
  Neurosci 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] Dipole source analysis of temporal slow waves in the elderly.2008
- Author(s)
  Motomura E, Inui K, Ogawa H, Nakase S, Hamanaka K, Honda T, Shiroyama T, Matsumoto T, Komori T, Okada M, Kakigi R.
- Journal Title
  
  Neuropsychobiology 57
  
  Pages: 9-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] A functional near-infrared spectroscopy study on the basic word order in Japanese2008
- Author(s)
  Nishimura Y, Sugisaki K, Hattori N, Inokuchi Y, Nishimura Y, Ogawa M, Okada M, Okazaki Y, Taki W, Yamamoto T, Yoshida E, Avano S.
- Journal Title
  
  Neuroreport 19
  
  Pages: 915-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Population estimation of the effects of cytochrome P450 2C19 and 3A5 polymorphisms on zonisamide clearance2008
- Author(s)
  Okada Y, Seo T, Wanibuchi A, HashimotoN, Higa Y, Ishitsu T, Nakagawa K.
- Journal Title
  
  Ther Drug Monit 30
  
  Pages: 540-543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, Mori F, Takahara T, Saito R, Miura Y, Kishi A, Tomiyama M, Sato A, Kojima T, Fukuma G, Wakabayashi K, Hase K, Ohno H, Kijima H, Takano Y, Mitsudome A, Kaneko S, Hirose S.
- Journal Title
  
  J Neurosci 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Associations between psychotic-like experiences and mental health status and other psychopathologies among Japanese early teens.2008
- Author(s)
  Nishida A, Tanii H, Nishimura Y, Kajiki N, Inoue K, Okada M, Sasaki T, Okazaki Y.
- Journal Title
  
  Schizophr Res (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659330
[Journal Article] 【神経科学の進歩と神経疾患治療】最新のてんかん理論と新しい抗てんかん薬2008
- Author(s)
  岡田元宏, 松本卓也, 樫本香苗
- Journal Title
  
  医薬ジャーナル 44
  
  Pages: 710-714
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] A functional near-infrared spectroscopy study on the basic word order in Japanese.2008
- Author(s)
  Nishimura Y, Sugisaki K, Hattori N, Inokuchi Y, Nishimura Y, Ogawa M, Okada M, Okazaki Y, Taki W, Yamamoto T, Yoshida E, Ayano S.
- Journal Title
  
  Neuroreport 19
  
  Pages: 915-919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, Mori F, Takahara T, Saito R, Miura Y, Kishi A, Tomiyama M, Sato A, Kojima T, Fukuma G, Wakabayashi K, Hase K, Ohno H, Kijima H, Takano Y, Mitsudome A, Kaneko S, Hirose S.
- Journal Title
  
  J Neurosci 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Dipole Source Analysis of Temporal Slow Waves in the Elderly2008
- Author(s)
  Motomura E, Inui K, Ogawa H, Nakase S, Hamanaka K, Honda T, Shiroyama T, Matsumoto T, Komori T, Okada M, Kakigi R.
- Journal Title
  
  Neuropsychobiology 57
  
  Pages: 9-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, Mori F, Takahata T, Saito R, Miura Y, Kishi A, Tomiyama M, Sato A, Kojima T, Fukuma G, Wakabayashi K, Hase K, Ohno H, Kijima H, Takano Y, Mitsudome A, Kaneko S, Hirose S.
- Journal Title
  
  J Neurosci 28(49)
  
  Pages: 12465-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] A functional near-infrared spectroscopy study on the basic word order in Japanese2008
- Author(s)
  Nishimura, Y., K.Sugisaki, N.Hattori, Y.Inokuchi, Y.Nishimura, M.Ogawa, M.Okada, Y.Okazaki, W.Taki, T.Yamamoto, E.Yoshida, S.Ayano.
- Journal Title
  
  NeuroReport 19.
  
  Pages: 915-919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20320058
[Journal Article] Staphylococcal enterotoxin induces emesis through increasing serotonin release in intestine and it is downregulated by cannabinoid receptor 1.2007
- Author(s)
  Hu DL, Zhu G, Mori F, Omoe K, Okada M, Wakabayashi K, Kaneko S, Shinagawa K, Nakane A.
- Journal Title
  
  Cell Microbiol 9
  
  Pages: 2267-2277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor.2007
- Author(s)
  Yoshida S, Okada M, Zhu G, Kaneko S.
- Journal Title
  
  Neuropharmacology 52
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] てんかんの責任遺伝子探索と遺伝子多型に基づいた個別化治療の開発.2007
- Author(s)
  兼子直, 岩佐博人, 古郡規雄, 岡田元宏, 土嶺章子, 佐々木智美, 藤井学, 吉田秀一, 廣瀬伸一, 伊藤正利, 小国弘量, 大澤真木子, 前澤真理子, 小島俊男, 金井数明, 和田一丸.
- Journal Title
  
  厚生労働省精神・神経疾患研究委託費(16指-3)研究報告書
  
  Pages: 87-93
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] Frontal dysfunction during a cognitive task in drug-naive patients with panic disorder as investigated by multi-channel near-infared spectroscopy imaging.2007
- Author(s)
  Nishimura Y, Tanii H, Fukuda M, Kajiki N, Inoue K, Kaiya H, Nishida A, Okada M, Okazaki Y.
- Journal Title
  
  Neurosci Res. 59
  
  Pages: 107-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor.2007
- Author(s)
  Yoshida, S., Okada, M., Zhu, G. & Kaneko, S.
- Journal Title
  
  Neuropharmacol. 52(7)
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Chrna 4に異常を持つ遺伝子改変モデル動物の神経科学的解析.2007
- Author(s)
  廣瀬伸一, 岡田元宏, 朱剛, 上野伸哉, 吉田淑子, 福間五龍, 斎藤亮, 高野行夫, 兼子直, 満留昭久.
- Journal Title
  
  厚生労働省精神・神経疾患研究委託費(16指-3)研究報告書
  
  Pages: 81-86
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] Staphylococcal enterotoxin induces emesis through increasing serotonin release in intestine and it is downregulated by cannabinoid receptor 1.2007
- Author(s)
  Hu, D.L., Zhu, G., Mori, F., Omoe, K., Okada, M., Wakabayashi, K., Kaneko, S., Shinagawa, K., Nakane, A.
- Journal Title
  
  Cell Microbiol 9
  
  Pages: 2267-2277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Chrna 4に異常を持つ遺伝子改変モデル動物の神経科学的解析.2007
- Author(s)
  廣瀬伸一, 岡田元宏, 朱剛, 上野伸哉, 吉田淑子, 福間五龍, 斎藤亮, 高野行夫, 兼子直, 満留昭久.
- Journal Title
  
  厚生労働省精神・神経疾患研究委託費(16指-3)研究報告書
  
  Pages: 81-86
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Mutation screening of AP3M2 in Japanese epilepsy patients.2007
- Author(s)
  Huang, M., Okada, M., Nakatsu, F., Oguni, H., Ito, M., Morita, K., Nagafuji, H., Hirose, S., Sakaki, Y., Kaneko. S., Ohno, H.&Kojima, T.
- Journal Title
  
  Brain & development 29
  
  Pages: 462-467
- NAID
  10024136602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] ヒトてんかんと遺伝子導入モデル動物を用いたてんかんの病態解明.2007
- Author(s)
  廣瀬伸一, 岡田元宏, 朱剛, 上野伸哉, 吉田淑子, 福間五龍, 斎藤亮, 高野行夫, 兼子直, 満留昭久.
- Journal Title
  
  てんかん治療研究振興財団研究年報 18
  
  Pages: 49-54
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] てんかんの責任遺伝子探索と遺伝子多型に基づいた個別化治療の開発.2007
- Author(s)
  兼子直, 岩佐博人, 古郡規雄, 岡田元宏, 土嶺章子, 佐々木智美, 藤井学, 吉田秀一, 廣瀬伸一, 伊藤正利, 小国弘量, 大澤真木子, 前澤真理子, 小島俊男, 金井数明, 和田一丸.
- Journal Title
  
  厚生労働省精神・神経疾患研究委託費(16指-3)研究報告書
  
  Pages: 87-93
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced. by hyperactivation of ryanodine receptor.2007
- Author(s)
  Yoshida, S., Okada, M., Zhu, G.&Kaneko, S.
- Journal Title
  
  Neuropharmacol 52(7)
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor.2007
- Author(s)
  Yoshida S, Okada M, ZhuG, Kaneko S.
- Journal Title
  
  Neuropharmacology 52
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659330
[Journal Article] Staphylococcal enterotoxin induceces emesis though increasing serotonin release in intestine is downregulated by cannbinoid receptor 1.2007
- Author(s)
  Hu, DL., Zhu, G, Mori, F., Omoe, K., Okada, M., Wakabayashi, K., Kaneko, S., Shinagawa, K.&Nakane A.
- Journal Title
  
  Cell. Microbiol. 9(9)
  
  Pages: 2267-2277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] 【てんかん診療の新たなる展開】てんかん診療の新たなる展開2007
- Author(s)
  八木和一, 高橋孝雄, 赤松直樹, 加藤天美, 岡田元宏
- Journal Title
  
  MEDICO 38
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Staphylococcal enterotoxin induces emesis through increasing serotonin release in intestine and it is downregulated by cannabinoid receptor 1.2007
- Author(s)
  Hu DL, Zhu G, Mori F, Omoe K, Okada M, Wakabayashi K, Kaneko S, Shinagawa K, Nakane A.
- Journal Title
  
  Cell Microbiol. 9
  
  Pages: 2267-2277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] Staphylococcal enterotoxin induceces emesis though increasing serotonin release in intestine is downregulated by cannbinoid receptor 1.2007
- Author(s)
  Hu, DL., Zhu, G, Mori, F., Omoe, K., Okada, M., Wakabayashi, K., Kaneko, S., Shinagawa, K. & Nakane A.
- Journal Title
  
  Cell. Microbiol., 9(9)
  
  Pages: 2267-2277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Staphylococcal enterotoxin induces emesis through increasing serotonin release in intestine and it is downregulated by cannabinoid receptor 1.2007
- Author(s)
  Hu Dl, Zhu G, Mori F, Omoe K, Okada M, Wakabayashi K, Kaneko S, Shinagawa K, Nakane A.
- Journal Title
  
  Cell Microbiol 9
  
  Pages: 2267-2277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659330
[Journal Article] Frontal dysfUnction during a cognitive task in drug-naive patients withpanic disorder as investigated by multi-channel near-infrared spectroscopy imaging.2007
- Author(s)
  Nishimura Y, Tanii H, FukudaM, Kajiki N, Inoue K, Kaiya H, Nishida A, Okada M, Okazaki Y.
- Journal Title
  
  Neurosci Res. 59
  
  Pages: 107-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659330
[Journal Article] Carbamazepine prevents breakdown ofneurotransmitter release induced byhyperactivation of ryanodine receptor2007
- Author(s)
  Yoshida S, Okada M, Zhu G, Kaneko S.
- Journal Title
  
  Neuropharmacology 52
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] Mutation screening of AP3M2 in Japanese epilepsy patients.2007
- Author(s)
  Hung MC, Okada M, Nakatsu F, Oguni H, Ito M, Morita K, Nagafuji H, Hirose S, Sakaki Y, Kaneko S, Ohno H, Kojima T
- Journal Title
  
  Brain Dev-Jpn (in press)
- NAID
  10024136602
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor2007
- Author(s)
  Yoshida S, Okada M, Zhu G, Kaneko S
- Journal Title
  
  Neuropharmacology 52
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor.2007
- Author(s)
  Yoshida S, Okada M, Zhu G, Kaneko S.
- Journal Title
  
  Neuropharmacology 52
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] ヒトてんかんと遺伝子導入モデル動物を用いたてんかんの病態解明.2007
- Author(s)
  廣瀬伸一, 岡田元宏, 朱剛, 上野伸哉, 吉田淑子, 福間五龍, 斎藤亮, 高野行夫, 兼子直, 満留昭久.
- Journal Title
  
  てんかん治療研究振興財団研究年報 18
  
  Pages: 49-54
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Mutation screening of AP3M2 in Japanese epilepsy patients.2007
- Author(s)
  Huang, M., Okada, M., Nakatsu, F., Oguni, H., Ito, m M., Morita, K., Nakafuji, H., Hirose, S., Sakaki, Y., Kaneko, S., Ohno, H. & Kojima, T.
- Journal Title
  
  Brain & development, 29
  
  Pages: 462-467
- NAID
  10024136602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor2007
- Author(s)
  Yoshida S, Okada M, Zhu G, Kaneko S.
- Journal Title
  
  Neuropharmacology 52(7)
  
  Pages: 1538-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Involvement of Ca^<2+>-induced Ca^<2+> releasing system in interleukin-1 β-associated adenosine release.2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Hirose S, Wakabayashi K, Kaneko S.
- Journal Title
  
  Eur J Pharmacol 532
  
  Pages: 246-252
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Epilepsy model animal bearing a genetic abnormality identified in human epilepsy2006
- Author(s)
  Hirose S, Okada M, Zhu G, Ueno S, Yoshida S, Fukuma G, Saito R, Takano Y, Kaneko S, Mitsudome A.
- Journal Title
  
  Brain Science Mental Disorders 17
  
  Pages: 157-160
- NAID
  10029853244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Effects of interleukin-1beta on hippocampal glutamate and GABA releasesassociated with Ca^<2+>-induced Ca^<2+>releasing systems2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S.
- Journal Title
  
  Epilepsy Res. 71(2-3)
  
  Pages: 107-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Involvement of Ca^<2+>-induced Ca^<2+> releasing system in interleukin-lβ-associated adenosine release2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Hirose S, Wakabayashi K, Kaneko S
- Journal Title
  
  Eur J Pharmacol 532
  
  Pages: 246-252
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Involvement of Ca^<2+>-induced Ca^<2-> releasing system in interleukin-1 β-associated adenosine release.2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Hirose S, Wakabayashi K, Kaneko S
- Journal Title
  
  Eur J Pharmacol 532
  
  Pages: 246-252
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] ヒトてんかんと同じ遺伝子異常をもつモデル動物2006
- Author(s)
  廣瀬伸一, 岡田元宏, 朱剛, 上野伸哉, 吉田淑子, 福間五龍, 兼子直
- Journal Title
  
  脳と精神の医学 17
  
  Pages: 157-160
- NAID
  10029853244
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Involvement of Ca^<2+>-induced Ca^<2+> releasing system in interleukin-1β-associated adenosine release2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Hirose S, Wakabayashi K, Kaneko S.
- Journal Title
  
  European Journal of Pharmacology 532
  
  Pages: 246-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Effects of interleukin-1β on hippocampal glutamate and GABA releases associated with Ca^<2+> -induced Ca^<2+> releasing systems2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S
- Journal Title
  
  Epilepsy Res 71
  
  Pages: 107-116
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Determination of genomic breakpoints in an epileptic patient using genotyping array2006
- Author(s)
  Kojima T, Mukai W, Fuma D, Ueda Y, Okada M, Sakaki Y, Kaneko S.
- Journal Title
  
  BiochemBiophys Res Commun 341
  
  Pages: 792-796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Excegran.2006
- Author(s)
  岡田元宏, 兼子直
- Journal Title
  
  こころの治療ハンドブック第4版(青葉安里, 諸川由実代 (Eds.))
  
  Pages: 164-165
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of interleukin-lbeta on hippocampal glutamate and GABA releases associated with Ca2+-induced Ca2+ releasing systems.2006
- Author(s)
  Gang Zhu, G., Okada, M., Yoshida, S., Mori, F., Ueno, S., et al.
- Journal Title
  
  Epilepsy Res 71・2-3
  
  Pages: 107-116
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] Effects of interleukin-1beta on hippocampal glutamate and GABA releases associated with Ca2+-induced Ca2+ releasing systems.2006
- Author(s)
  Zhu, G., Okada, M., Yoshida, S., Mori, F., Ueno, S., Wakabayashi, K., Kaneko, S.
- Journal Title
  
  Epilepsy Res 71
  
  Pages: 107-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Determination of genomic breakpoints in an eplepticpatient using genotyping array.2006
- Author(s)
  Kojima T, Mukai W, Fuma D, Ueda Y, Okada M, Sakaki Y, Kaneko S
- Journal Title
  
  Biochem Bioph Res Co 341(3)
  
  Pages: 792-796
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] Involvement of Ca^<2+>-induced Ca^<2+>releasing system in interlerkin-1beta-associatedadenosine release2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Hirose S, Wakabayashi K, Kaneko S.
- Journal Title
  
  Eur J Pharmacol 532(3)
  
  Pages: 246-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Involvement of Ca^<2+>-induced Ca^<2+> releasing system in interleukin-1 β-associated adenosine release.2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Hirose S, Wakabayashi K, Kaneko S
- Journal Title
  
  Eur J Pharmacol 532
  
  Pages: 246-252
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] Epilep patitmal/Zarontin.2006
- Author(s)
  岡田元宏, 兼子直
- Journal Title
  
  こころの治療ハンドブック第4版(青葉安里, 諸川由実代 (Eds.))
  
  Pages: 166-167
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Determination of genomic breakpoints in an epileptic patient using genotyping array.2006
- Author(s)
  Kojima T, Mukai W, Fuma D, Ueda Y, Okada M, Sakaki Y, Kaneko S
- Journal Title
  
  Biochem Bioph Res Co 341(3)
  
  Pages: 792-796
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Effects of interleukin-lβ on hippocampal glutamate and GABA releases associated with Ca^<2+>-induced Ca^<2+> releasing systems2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S
- Journal Title
  
  Epilepsy Res 71
  
  Pages: 107-116
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Generation of epilepsy model animal bearing a genetic abnormality identified in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) of human2006
- Author(s)
  Okada M, Zhu G, Ueno S, Yoshida S, Kaneko S.
- Journal Title
  
  Annual Report of Pharmacopsychiatry Research 38
  
  Pages: 191-196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Effects of interleukin-1β on hippocampal glutamate and GABA releases associated with Ca^<2+>-induced Ca^<2+> releasing systems2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S
- Journal Title
  
  Epilepsy Research 17
  
  Pages: 107-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Involvement of Ca^<2+> -induced Ca^<2+> releasing system in interleukin-1β-associated adenosine release2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Hirose S, Wakabayashi K, Kaneko S
- Journal Title
  
  Eur J Pharmacol 532
  
  Pages: 246-252
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Effects of interleukin-1 β on hippocampal glutamate and GABA releases associated wuth Ca^<2+>-induced Ca^<2+> releasing systems.2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S
- Journal Title
  
  Epilepsy Res 71(2-3)
  
  Pages: 107-116
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] ヒトてんかんと同じ遺伝子異常をもつ組換え動物の作出2006
- Author(s)
  岡田元宏, 朱剛, 上野伸哉, 吉田淑子, 兼子直
- Journal Title
  
  精神薬療研究年報 38
  
  Pages: 191-196
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590856
[Journal Article] Effects of interleukin-1beta on hippocampal glutamate and GABA releases associated with Ca2+-induced Ca2+ releasing systems2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S
- Journal Title
  
  Epilepsy Res 71
  
  Pages: 107-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects of interleukin-1 β on hippocampal glutamate and GABA releases associated wuth Ca^<2+>-induced Ca^<2+> releasing systems.2006
- Author(s)
  Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S
- Journal Title
  
  Epilepsy Res 71
  
  Pages: 107-116
- Data Source
  KAKENHI-PROJECT-18023005
[Journal Article] Involvement of Ca2+-induced Ca2+ releasing system in interleukin-1beta-associated adenosine release.2006
- Author(s)
  Zhu, G., Okada, M., Yoshida, S., Mori, F., Hirose, S., Wakabayashi, K., Kaneko, S.
- Journal Title
  
  Eur J Pharmacol 532
  
  Pages: 246-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Journal Article] Effects ofinterleukin-1beta on hippocampalglutamate and GABA releases associatedwith Ca2+-induced Ca2+ releasing systems2006
- Author(s)
  Gang Zhu, G., Okada, M., Yoshida, S. Mori, F. Ueno, S. , et.al.
- Journal Title
  
  Epilepsy Res 71
  
  Pages: 107-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex.2005
- Author(s)
  Huang CW, Ueno S, Okada M, Kaneko S
- Journal Title
  
  Epilepsy Res 67
  
  Pages: 51-60
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Genetics of idiopathic epilepsies.2005
- Author(s)
  Hirose S, Mitsudome A, Okada M, Kaneko S
- Journal Title
  
  Epilepsia 46(1)
  
  Pages: 38-43
- NAID
  10016481115
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] A novel de novo KCNQ2 mutation in a sporadic case of benign neomatal convulsions.2005
- Author(s)
  Ishii Ai, Fukuma G, Uehara A, Miyajima T, Makita Y, Hamachi A, Yasukochi M, Inoue T, Okada M, Kaneko S, Akihisa M, Hirose S
- Journal Title
  
  Epilepsia 46(Suppl 2)
  
  Pages: 3-4
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Impairment of monoaminergic transmission in μ3B knockout mice.2005
- Author(s)
  Zhu G, Okada M, Nakatsu F, Mori F, Yoshida S, Wakabayashi K, Ohno H, Kaneko S
- Journal Title
  
  Epilepsia 46(Suppl 3)
  
  Pages: 11-12
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] てんかんの分子遺伝学研究のUp to date2005
- Author(s)
  兼子直, 金井数明, 福間五龍, 岡田元宏, 桑原聡, 廣瀬伸一
- Journal Title
  
  ゲノム医学 5(3)
  
  Pages: 241-245
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Protein kinase associated with gating and closing transmission mechanisms in temporoammonic pathway.2005
- Author(s)
  Okada M., et al.
- Journal Title
  
  Neuropharmacology 47
  
  Pages: 485-504
- Data Source
  KAKENHI-PROJECT-15390329
[Journal Article] Effects of zonisamide on neurotransmitter exocytosis associated with ryanodine receptors2005
- Author(s)
  Yoshida S, Okada M, Zhu G, Kaneko S
- Journal Title
  
  Epilepsy Res. 67(3)
  
  Pages: 153-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Effects of ryanodine receptor activation on neurotransmitter release and neruronal cell death following kainic acid-induced status epilepticus2005
- Author(s)
  Mori F, Okada M, Tomiyama M, Kaneko S, Wakabayshi K.
- Journal Title
  
  Epilepsy Res 65(1-2)
  
  Pages: 59-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Effects of carbamazepine on mechanism of Ca2+-induced Ca2+ releasing system-associated exocytosis.2005
- Author(s)
  Okada M, Zhu Gang, Yoshida S, Mori F, Wakabayashi K, Kaneko S
- Journal Title
  
  Epilepsia 46(Suppl 2)
  
  Pages: 15-16
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Age-Dependent impaiement of GABAergic transmission in μ3B knockout mice.2005
- Author(s)
  Zhu G, Okada M, Mori F, Nakatsu F, Yoshida S, Wakabayashi K, Ohno H, Kaneko S
- Journal Title
  
  Epilepsia 46(Suppl 2)
  
  Pages: 2-2
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Determination of genomic breakpoints in an epileptic patient using genotyping array.2005
- Author(s)
  Kojima T, Mukai W, Fuma D, Ueda Y, Okada M, Sakai Y, Kaneko S
- Journal Title
  
  Biochem Biophys Res Commun 341(3)
  
  Pages: 792-796
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Biphasic actions of topiramate on monoamine exocytosis associated with both soluble N-ethylmaleimide-sensitive factor attachment protein receptors and Ca(2+)-induced Ca(2+)-releasing systems2005
- Author(s)
  Okada M et al.
- Journal Title
  
  Neuroscience 134
  
  Pages: 233-246
- Data Source
  KAKENHI-PROJECT-17025004
[Journal Article] ヒトてんかんと同じ遺伝子異常をもつ組換え動物の作出2005
- Author(s)
  岡田元宏, 朱剛, 上野伸哉, 吉田淑子, 福間五龍, 廣瀬伸一, 兼子直
- Journal Title
  
  精神薬療研究年報 37
  
  Pages: 160-164
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Biphasic actions of topiramate on monoamine exocytosis associated with both soluble N-ethylmaleimide-sensitive factor attachment protein receptors and Ca(2+)-induced Ca(2+)-releasing systems2005
- Author(s)
  Okada M et al.
- Journal Title
  
  Neuroscience 134
  
  Pages: 233-246
- Data Source
  KAKENHI-PROJECT-15659267
[Journal Article] Epileptic seizure in mice deficient in μ3B subunit of AP-3B complex.2005
- Author(s)
  Nakatsu F, Okada M, Mori F, Kumazawa N, Iwasa H, Zhu G, Kasagi Y, Kamiya H, Harada A, Nishimura K, Takeuchi A, Miyazaki T, Watanabe M, Yasa D, Manabe T, Wakabayashi K, Kaneko S, Saito T, Ohno H
- Journal Title
  
  Epilepsia 46(Suppl 2)
  
  Pages: 67-68
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex2005
- Author(s)
  Huang CW, Ueno S, Okada M, Kaneko S.
- Journal Title
  
  Epilepsy Res 67
  
  Pages: 51-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Down-regulation of CICR gene expression by carbamazepine, via stimulation of CICR associated monoamine exocytosis.2005
- Author(s)
  Okada M, Yoshida S, Zhu G, Ueno S, Kaneko S
- Journal Title
  
  J Pharmacol Sci 97(Suppl 1)
  
  Pages: 78-78
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Effects of zonisamide on neurotransmitter exocytosis associated with ryanodine receptors.2005
- Author(s)
  Yoshida S, Okada M, Zhu G, Kaneko S
- Journal Title
  
  Epilepsy Res 67(3)
  
  Pages: 153-162
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Zonisamido at clinically relevant concentrations inhibits evoked EPSP but not presynaptic fiber volley in rat frontal cortex.2005
- Author(s)
  Huang CW, Ueno S, Okada M, Kaneko S
- Journal Title
  
  J Pharmacol Sci 97(Suppl 1)
  
  Pages: 268-268
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Biphasic actions of topiramete on monamine exocytosis associated with both soluble N-ethylmateimide-sensitive factor attachment protein receptors and Ca^<2+>-induced Ca^<2+>-releasing systems2005
- Author(s)
  Okada M, Yoshida S, Zhu G, Hirose S, Kaneko S.
- Journal Title
  
  Neuroscience 134(1)
  
  Pages: 233-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] てんかん -責任遺伝子解明の進展とその後の課題-2005
- Author(s)
  兼子直, 金井数明, 岡田元宏, 桑原聡, 廣瀬伸一
- Journal Title
  
  実験医学 23(5)
  
  Pages: 776-781
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Effects of ryanodine receptor activation on neurotransmitter release and neuronal cell death following kainic acid-induced status epilepticus.2005
- Author(s)
  Mori F, Okada M, Tomiyama M, Kaneko S, Wakabayashi K
- Journal Title
  
  Epilepsy Res 65(1-2)
  
  Pages: 59-70
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Genetics of idiopathic epilepsies.2005
- Author(s)
  Hirose S, Mitsudome A, Okada M, Kaneko S, on behalf of The Epilepsy Study Group, Japan
- Journal Title
  
  Epilepsia 46(Suppl 1)
  
  Pages: 38-43
- NAID
  10016481115
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Biphasic action of topiramate on monoamine exocytosis associated with both soluble N-ethylmaleimide-sensitive factor attachment protein receptors and Ca^<2+>-induced Ca^<2+>-releasing systems.2005
- Author(s)
  Okada M, Yoshida S, Zhu G, Hirose S, Kaneko S
- Journal Title
  
  Neuroscience 134
  
  Pages: 233-246
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Protein kinase associated with gating and closing transmission mechanisms in temporoammonic pathway.2004
- Author(s)
  Okada M.et al.
- Journal Title
  
  Neuropharmacology 47・4
  
  Pages: 485-504
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570903
[Journal Article] Protein kinase associated with gating and closing transmission mechanisms in temporoammonic pathway.2004
- Author(s)
  Okada M. et al.
- Journal Title
  
  Neuropharmacology 47・4
  
  Pages: 485-504
- Data Source
  KAKENHI-PROJECT-15659267
[Journal Article] マイクロダイアリーシスを用いた神経伝達物質開口分泌機構の解明2004
- Author(s)
  岡田元宏, 他
- Journal Title
  
  日本神経精神薬理学雑誌 24
  
  Pages: 165-170
- NAID
  10015423137
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Protein kinase associated with gating and closing transmission mechanisms in temporoammonic pathway.2004
- Author(s)
  Okada M. et al.
- Journal Title
  
  Neuropharmacology 47-4
  
  Pages: 485-504
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570903
[Journal Article] Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.2004
- Author(s)
  Nakatsu F, Okada M, Mori F et al.
- Journal Title
  
  Journal of Cell Biology 167・2
  
  Pages: 293-302
- NAID
  120004898419
- Data Source
  KAKENHI-PROJECT-15591208
[Journal Article] Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.2004
- Author(s)
  Nakatsu F, Okada M, Mori F et al.
- Journal Title
  
  J Cell Biol 167
  
  Pages: 293-302
- NAID
  120004898419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591208
[Journal Article] リバースゲノミクス的研究手法を用いた中枢系機能性疾患におけるERストレス仮説の構築2004
- Author(s)
  岡田元宏, 他
- Journal Title
  
  精神薬療基金研究年報 36
  
  Pages: 74-82
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Protein kinase associated with gating and closing transmission mechanisms in temporoammonic patyway.2004
- Author(s)
  Okada M, et al.
- Journal Title
  
  Neuropharmacol 47/4
  
  Pages: 485-504
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.2004
- Author(s)
  Nakatsu F, Okada M, Mori F, et al.
- Journal Title
  
  J Cell Biol 167-2
  
  Pages: 293-302
- NAID
  120004898419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591208
[Journal Article] Both DOPA and dopamine releases are regulated by Ca^<2+> induced Ca^<2+> releasing system in rat striatum.
- Author(s)
  Okada, M., et al.
- Journal Title
  
  Neurosci Lett (in press)
- Data Source
  KAKENHI-PROJECT-15390329
[Journal Article] Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor.
- Author(s)
  Yoshida, S., Okada, M., Zhu, G., Kaneko, S.
- Journal Title
  
  Neuropharmacology 52
  
  Pages: 1538-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390316
[Patent] けいれん性疾患に関連する遺伝子変異とけいれん性疾患診断方法2006
- Inventor(s)
  小島俊男・廣瀬伸一・岡田元宏・兼子直
- Industrial Property Rights Holder
  国立大学法人弘前大学・独立行政法人理化学研究所・学校法人福岡大学
- Patent Publication Number
  2006-325500
- Acquisition Date
  2006-12-07
- Data Source
  KAKENHI-PROJECT-18390316
[Patent] けいれん性疾患に関連する遺伝子変異とけいれん性疾患診断方法2006
- Inventor(s)
  小島俊男, 廣瀬伸一, 岡田元宏, 兼子直
- Industrial Property Rights Holder
  小島俊男, 廣瀬伸一, 岡田元宏, 兼子直
- Industrial Property Number
  2005-155133
- Acquisition Date
  2006-12-07
- Data Source
  KAKENHI-PROJECT-16109006
[Patent] てんかんモデル動物(CHRNA4:S284L)2005
- Inventor(s)
  廣瀬伸一, 兼子直, 岡田元宏, 斉藤亮
- Industrial Property Rights Holder
  廣瀬伸一, 兼子直, 岡田元宏, 斉藤亮
- Industrial Property Number
  2004-062907
- Acquisition Date
  2005-09-15
- Overseas
- Data Source
  KAKENHI-PROJECT-16109006
[Patent] てんかんモデル動物(CHRNA4:S284L)2004
- Inventor(s)
  廣瀬伸一, 兼子直, 岡田元宏, 斉藤亮
- Industrial Property Rights Holder
  廣瀬伸一, 兼子直, 岡田元宏, 斉藤亮
- Industrial Property Number
  2004-062907
- Filing Date
  2004-03-05
- Data Source
  KAKENHI-PROJECT-16109006
[Presentation] グリアとてんかん：アストロサイト Kir4.1 チャネルの病態解析を中心に2017
- Author(s)
  大野行弘、福田敦夫、岡田元宏、小泉修一
- Organizer
  第５１回　日本てんかん学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04892
[Presentation] CysLT1/CysLT2 受容体デュアル拮抗剤の抗けいれん作用につい2017
- Author(s)
  植田勇人、岡田元宏
- Organizer
  第５１回　日本てんかん学会
- Data Source
  KAKENHI-PROJECT-15H04892
[Presentation] 抗けいれん薬と抗てんかん薬としての作用機序2017
- Author(s)
  岡田元宏
- Organizer
  第５１回　日本てんかん学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04892
[Presentation] 新たな治療標的としてのグリア伝達2013
- Author(s)
  岡田元宏
- Organizer
  47回日本てんかん学会学術集会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-22390224
[Presentation] Mechanisms of absence epilepsy Varidation criteria for genetic animal models of epilepsy2012
- Author(s)
  Okada M
- Organizer
  9thAsian & Oceanian Epilepsy Congress
- Place of Presentation
  Manila
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23659564
[Presentation] Epilepsy genes and beyond2012
- Author(s)
  Okada M
- Organizer
  9TH ASIAN & OCEANIAN EPILEPSY CONGRESS(招待講演)
- Place of Presentation
  Manila
- Data Source
  KAKENHI-PROJECT-23659564
[Presentation] Epilepsy genes and beyond2012
- Author(s)
  Okada M
- Organizer
  9thAsian & Oceanian Epilepsy Congress
- Place of Presentation
  Manila
- Year and Date
  2012-03-22
- Data Source
  KAKENHI-PROJECT-23659564
[Presentation] Epilepsy genes and beyond2012
- Author(s)
  Okada M
- Organizer
  9TH ASIAN & OCEANIAN EPILEPSY CONGRESS
- Place of Presentation
  Manila(招待講演)
- Year and Date
  2012-03-22
- Data Source
  KAKENHI-PROJECT-22390224
[Presentation] ILAE Lecture: Varidation criteria for genetic animal models of epilepsy2012
- Author(s)
  Okada M
- Organizer
  9thAsian & Oceanian Epilepsy Congress
- Place of Presentation
  Manila
- Year and Date
  2012-03-21
- Data Source
  KAKENHI-PROJECT-23659564
[Presentation] 「個別化治療up to date : 遺伝子診断の現状と治療への応用」(指定討論)2012
- Author(s)
  岡田元宏
- Organizer
  46回日本てんかん学会学術集会
- Place of Presentation
  都市センターホテル
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-22390224
[Presentation] 新規てんかん薬物療法のニーズ2011
- Author(s)
  岡田元宏
- Organizer
  第45回日本てんかん学会
- Place of Presentation
  新潟(招待講演)
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-22390224
[Presentation] 新規てんかん薬物療法のニーズ2011
- Author(s)
  岡田元宏
- Organizer
  第４５回日本てんかん学会(招待講演)
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-23659564
[Presentation] Children's Processing of Scrambled Sentences in Japanese : A NIRS Study2010
- Author(s)
  Ayano, S., K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, K.Tamari, S.Umeda, T.Yamamoto, E.Yoshida
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] A NIRS Study on Children's Processing of Word Order Variations in Japanese.2010
- Author(s)
  Ayano, S., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, K.Tamari, S.Umeda, T.Yamamoto, E.Yoshida.
- Organizer
  Neurobiology of Language Conference2010.
- Place of Presentation
  Rancho Bernardo, San Diego.
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] Prefrontal Development and Processing of Various Word Orders in Child Japanese.2010
- Author(s)
  Yamamoto, T., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, K.Tamari, S.Umeda, E.Yoshida, S.Ayano.
- Organizer
  Society for Neuroscience 2010.
- Place of Presentation
  San Diego Convention Center, San Diego.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] A NIRS Study on Children's Processing of Word Order Variations in Japanese2010
- Author(s)
  Ayano, S., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, K.Tamari, S.Umeda, T.Yamamoto, E.Yoshida
- Organizer
  Neurobiology of Language Conference2010
- Place of Presentation
  Rancho Bernardo, San Diego, U.S.A.
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] Children's Processing of Scrambled Sentences in Japanese : A NIRS Study.2010
- Author(s)
  Ayano, S., K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, K.Tamari, S.Umeda, T.Yamamoto, E.Yoshida.
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸国際会議場.
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] Prefrontal Development and Processing of Various Word Orders in Child Japanese2010
- Author(s)
  Yamamoto, T., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.-Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, K.Tamari, S.Umeda, E.Yoshida, S.Ayano
- Organizer
  Society for Neuroscience 2010
- Place of Presentation
  San Diego Convention Center, San Diego, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] Cortical Activations Related to Syntactic and Semantic Violations in Japanese : An fNIRS Study2009
- Author(s)
  Ayano, S., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, S.Umeda, T.Yamamoto, E.Yoshida
- Organizer
  Neurobiology of Language Conference 2009
- Place of Presentation
  Chicago Marriott Downtown Magnificent Mile
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] On the Modularity of Linguistic Knowledge : The View from a NIRS Experiment2009
- Author(s)
  Yamamoto, T., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, S.Umeda, E.Yoshida, S.Ayano
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago McCormick Place
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] Cortical Activation by Syntactic Violations in Japanese : An fNIRS Study2009
- Author(s)
  Ayano, S., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, S.Umeda, T.Yamamoto, E.Yoshida
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] 夜間前頭葉てんかんの変異遺伝子(S284L)導入ラット脳におけるニコチン性アセチルコリン受容体の発現.2009
- Author(s)
  森文秋, 冨山誠彦, 上野伸哉, 吉田淑子, 岡田元宏, 廣瀬伸一, 兼子直
- Organizer
  第43回日本てんかん学会
- Place of Presentation
  弘前
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18390316
[Presentation] De novo KCNQ2遺伝子変異が見出された良性新生児けいれんから中心一側頭部棘波を伴う小児良性てんかんへの移行症例.2009
- Author(s)
  石井敦士, 福間五龍, 上原明, 宮島祐, 蒔田芳男, 安元佐和, 井上貴仁, 岡田元宏, 兼子直, 廣瀬伸一
- Organizer
  第43回日本てんかん学会
- Place of Presentation
  弘前
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18390316
[Presentation] ADNFLE共存症病態の行動学的解析.2009
- Author(s)
  岸昭宏, 吉田淑子, 朱剛, 上野伸哉, 廣瀬伸一, 兼子直, 岡田元宏
- Organizer
  第43回日本てんかん学会
- Place of Presentation
  弘前
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18390316
[Presentation] プロテインキナーゼCに対するトピラマートの効果の検討.2009
- Author(s)
  吉田淑子, 岡田元宏, 吉田秀一, 兼子直
- Organizer
  第43回日本てんかん学会
- Place of Presentation
  弘前
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18390316
[Presentation] On the Modularity of Linguistic Knowledge : The View from a NIRS Experiment.2009
- Author(s)
  Yamamoto, T., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, S.Umeda, E.Yoshida, S.Ayano.
- Organizer
  Society for Neuroscience 2009.
- Place of Presentation
  Chicago McCormick Place.
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] Cortical Activations Related to Syntactic and Semantic Violations in Japanese : An fNIRS Study.2009
- Author(s)
  Ayano, S., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, S.Umeda, T.Yamamoto, E.Yoshida.
- Organizer
  Neurobiology of Language Conference2009.
- Place of Presentation
  Chicago Marriott Downtown Magnificent Mile.
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] Cortical Activation by Syntactic Violations in Japanese : An fNIRS Study.2009
- Author(s)
  Ayano, S., Y.Nishimura, K.Sugisaki, N.Hattori, Y.Inokuchi, S.Kojima, M.Komachi, Y.Nishimura, Y.Otsu, M.Ogawa, M.Okada, S.Umeda, T.Yamamoto, E.Yoshida.
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] ADNFLEモデルラットにおけるGABA伝達の障害機構.2009
- Author(s)
  上野伸哉, 山田順子, 右田啓介, 冨山誠彦, 吉田淑子, 岡田元宏, 森文秋, 若林孝一, 朱剛, 廣瀬伸一, 兼子直
- Organizer
  第43回日本てんかん学会
- Place of Presentation
  弘前
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18390316
[Presentation] P型電位依存性カルシウムチャネルコンディショナルノックダウンマウスを用いたてんかん分子病態の解析.2009
- Author(s)
  山村哲史, 小西康信, 齊藤浩充, 兼子直, 鈴木昇, 岡田元宏
- Organizer
  第43回日本てんかん学会
- Place of Presentation
  弘前
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18390316
[Presentation] S284Lトランスジェニックラット自発性けいれん発現機序の解明.2009
- Author(s)
  朱剛, 岡田元宏, 吉田淑子, 上野伸哉, 森文秋, 岸昭宏, 若林孝一, 廣瀬伸一, 兼子直
- Organizer
  第43回日本てんかん学会
- Place of Presentation
  弘前
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18390316
[Presentation] A De Novo KCNQ2 Mutation Detected in Benign Neonatal Convulsions : Possible Involvement Of Genes responsible for Rare Inherited Epilepsy in Idiopathic Epilepsy2008
- Author(s)
  Ishii A, Fukuma G, Uehara A, Yasukochi M, Miyajima T, Makita Y, Hamachi A, Yonetani M, Inoue T, Okada M, Kaneko S, and Hirose S.
- Organizer
  The 4^<th> Congress of Asian Society for Pediatric Research
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-16109006
[Presentation] Determination of neurotransmitter release in a novel spontaneous epilepsy model, Prip-1 knockout mice2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, Wakabayashi K, and Kaneko S.
- Organizer
  7^<th> Asian & Oceanian Epilepsy Congress
- Place of Presentation
  Xiamen, CHINA
- Data Source
  KAKENHI-PROJECT-16109006
[Presentation] Dose the place of the first panic attack predict future comorbid agora phobia?2008
- Author(s)
  Hara N, Nishimura Y, Tanii H, Inoue K, Nishida A, Yokoyama C, Okada M, Kaiya H, Okazaki Y.
- Organizer
  XIV World Congress of Psychiatry (WPA)
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20320058
[Presentation] DRIP-1遺伝子欠損マウスの自発性けいれん発現機序の解明.2007
- Author(s)
  朱剛, 岡田元宏, 吉田淑子, 吉田秀一, 森秋文, 上野伸哉, 兼松隆, 若林孝一, 兼子直.
- Organizer
  第41回日本てんかん学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18023005
[Presentation] DRIP-1遺伝子欠損マウスの自発性けいれん発現機序の解明.2007
- Author(s)
  朱剛, 岡田元宏, 吉田淑子, 吉田秀一, 森秋文, 上野伸哉, 兼松隆, 若林孝一, 兼子直.
- Organizer
  第41回日本てんかん学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-16109006
[Presentation] GABAA受容体輸送とIP3結合能を有するタンパク(RPIP-1)欠損マウスのフェノタイプ解析とその発症機構の検討2007
- Author(s)
  上野伸哉, 朱剛, 森文秋, 若林孝一, 吉田淑子, 上村雄一朗, 岡田元宏, 兼子直
- Organizer
  Neuro2007
- Place of Presentation
  横浜
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-18300137
[Presentation] てんかんの個別化治療の開発に関する研究.2007
- Author(s)
  兼子直, 岩佐博人, 古郡規雄, 岡田元宏, 土嶺章子, 佐々木智美, 藤井学, 吉田秀一, 廣瀬伸一, 石津棟暎, 小国弘量, 大澤真木子, 前澤真理子, 小島俊男, 金井数明, 和田一丸.
- Organizer
  平成19年度精神・神経疾患研究委託費(19指-6)研究報告会
- Place of Presentation
  東京
- Year and Date
  2007-12-16
- Data Source
  KAKENHI-PROJECT-16109006
[Presentation] 抗てんかん薬慢性投与による細胞内カルシウム放出(CICR)機構に対する発現変化の検討.2007
- Author(s)
  吉田淑子, 岡田元宏, 朱剛, 兼子直.
- Organizer
  第41回日本てんかん学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-16109006
[Presentation] てんかんの個別化治療の開発に関する研究.2007
- Author(s)
  兼子直, 岩佐博人, 古郡規雄, 岡田元宏, 土嶺章子, 佐々木智美, 藤井学, 吉田秀一, 廣瀬伸一, 石津棟暎, 小国弘量, 大澤真木子, 前澤真理子, 小島俊男, 金井数明, 和田一丸.
- Organizer
  平成19年度精神・神経疾患研究委託費(19指-6)研究報告会
- Place of Presentation
  東京
- Year and Date
  2007-12-16
- Data Source
  KAKENHI-PROJECT-18023005
[Presentation] 抗てんかん薬慢性投与による細胞内カルシウム放出(CICR)機構に対する発現変化の検討.2007
- Author(s)
  吉田淑子, 岡田元宏, 朱剛, 兼子直.
- Organizer
  第41回日本てんかん学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18023005
[Presentation] Transgenic Rats Harbouring a CHRNA4 Mutation Exhibit Characteristic Seizure Phenotypes of Nocturnal Frontal Lobe Epilepsy2005
- Author(s)
  S Hirose, M Okada, et. al.
- Organizer
  26th International Epilepsy Congress
- Place of Presentation
  Paris
- Year and Date
  2005-08-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390329

1. KANEKO Sunao (40106852)

# of Collaborated Projects: 10 results

# of Collaborated Products: 90 results
2. UENO Shinya (00312158)

# of Collaborated Projects: 8 results

# of Collaborated Products: 41 results
3. FUKUSAWA Masashi (10231557)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 6 results

# of Collaborated Products: 32 results
5. HIROSE Shinichi (60248515)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
6. ZHU Gang (80400133)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
7. MITSUDOME Akihisa (30038749)

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# of Collaborated Products: 0 results
8. MORI Fumiaki (60200383)

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# of Collaborated Products: 11 results
9. WADA Kazumaru (60241486)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
10. ARAKI Kimi (90211705)

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11. SATOH Kei (20125438)

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12. MORIYAMA Tomoko (90400134)

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13. MIZOGUTI Akira (90181916)

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14. SUZUKI Noboru (00202135)

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15. SAITO Mitsuhiro (50303722)

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16. DESHIMARU Masanobu (70309889)

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17. HAYAKARI Makoto (80156421)

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19. SUZUKI Tosirou

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20. YASUI-FURUKORI Norio (20333734)

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21. SHIMIZU Toshio (00110750)

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22. KOJIMA Toshio (00311340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
23. NAKAGAWA Kazuko (20284747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
24. YAMAKAWA Kazuhiro (30241235)

# of Collaborated Projects: 1 results

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25. TSUJI Shoji (70150612)

# of Collaborated Projects: 1 results

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26. KUWANO Ryozo (20111734)

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27. TOMIYAMA Masahiko (40311542)

# of Collaborated Projects: 1 results

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28. MIGITA Keisuke (10352262)

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29. YAMADA Junko (30334965)

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30. TANII Hisashi (40346200)

# of Collaborated Projects: 1 results

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31. KANEMATSU Takashi (10264053)

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32. SUZUKI Dai (30378301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
33. AYANO Seiki (00222703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
34. OTSU Yukio (80100410)

# of Collaborated Projects: 1 results

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35. SUGISAKI Koji (60362331)

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36. HATTORI Noriko (00198764)

# of Collaborated Projects: 1 results

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37. INOKUCHI Yasushi (90151638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
38. YOSHIDA Etsuko (00240276)

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# of Collaborated Products: 17 results
39. OGAWA Mariko (00185513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
40. UMEDA Satoshi (90317272)

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41. YAMAMOTO Tetsuro (00127002)

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55. 田村裕子 (30746722)

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56. 西川晃平 (90444439)

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58. YOSHIDA Shuichi

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69. 奥田真弘

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# of Collaborated Products: 1 results

Okada Motohiro 岡田 元宏

OKADA Motohiro 岡田 元宏

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Pathomechanisms of neuropsychiatric disorders associated with tripartite synaptic transmissionPrincipal Investigator

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Mechanisms of tripartite synaptic transmissionPrincipal Investigator

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中枢神経系機能性疾患におけるグリア伝達機能障害病態仮説の構築Principal Investigator

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Prevention of neuropsychiatric functional diseasePrincipal Investigator

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Exploring the development of functional disorders in central nervous systemPrincipal Investigator

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中枢神経系機能性疾患発症前治療介入の有効性検証Principal Investigator

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Generation of epilepsy model animal bearing a genetic abnormality identified in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) of humanPrincipal Investigator

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分子病態を基本とした前頭葉てんかんに対する薬力学的個別化治療の開発Principal Investigator

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Okada Motohiro 岡田元宏

OKADA Motohiro 岡田元宏