Katsura Toshiya 桂敏也

… Alternative Names

桂敏也カツラトシヤ

KATSURA Toshiya 桂敏也

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Researcher Number	10283615
Other IDs
External Links
Affiliation (Current)	2025: 立命館大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023: 立命館大学, 薬学部, 教授 2013 – 2021: 立命館大学, 薬学部, 教授 2012: 京都大学, 医学(系)研究科(研究院), 准教授 2007 – 2011: Kyoto University, 医学研究科, 准教授 2004 – 2006: 京都大学, 医学研究科, 助教授 … More 2003: 京都大学, 医学研究科, 助手 2002 – 2003: 京都大学, 医学研究科, 講師 1997 – 2001: KYOTO UNIVERSITY,Graduate School of Medicine, Instructor, 医学研究科, 助手 1999: 京都大学, 大学院・医学研究科, 助手 1997: 京都大学, 大学院・医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / Applied pharmacology / Complex systems / 応用薬理学・医療系薬学 / 医薬分子機能学 / Biological pharmacy Except Principal Investigator Medical pharmacy / 医薬分子機能学 / 応用薬理学・医療系薬学 / Biological Sciences / Applied pharmacology / Biological pharmacy
Keywords	Principal Investigator 薬物動態学 / トランスポータ / 薬物動態 / 細胞膜ターゲティング / トランスポーター / 薬学 / 膜輸送 / 極性上皮細胞 / 薬物相互作用 / 薬物トランスポーター … More / 培養細胞 / 腎排泄 / 医薬品適正使用 / 副作用 / 薬物トランスポータ / 有機アニオントランスポータ / 蛋白質間相互作用 / Caco-2 / ペプチドトランスポータ / PEPT1 / 母集団薬物動態解析 / ゲノム薬理学 / 直接作用型経口抗凝固薬 / in vitro評価 / 経細胞輸送 / 尿細管分泌 / 組織移行性 / 遺伝子多型 / regulation of expression / pharmacokinetics / membrane transport / membrane targeting / organic anion transporter / polarized epithelial cells / 発現調節 / 生理学 / 腎臓 / シミュレーション / 有機カチオントランスポータ / PDZドメイン / 薬物体内動態 / 甲状腺機能亢進症 / P-糖蛋白質 / 甲状腺ホルモン / 三級アミン輸送体 / 小腸刷子縁膜 / 三級アミン逆輸送体 / H^+ / 分泌 / 消化管吸収 / 薬物吸収 / リ-ティング / 上皮細胞 / LLC-PK_1 / 腎上皮細胞 / ソーティング … More Except Principal Investigator ペプチドトランスポータ / 有機アニオントランスポータ / 尿細管分泌 / 有機カチオントランスポータ / 薬物トランスポータ / 薬物輸送 / 薬物動態 / 薬物相互作用 / テトラエチルアンモニウム / P-糖タンパク質 / Organic cation transporter / Organic anion transporter / Drug transport / 有機カチオン / 有機アニオン / 腎臓 / 遺伝子多型 / 発現プロファイル / トランスポートソーム / 発現調節 / トランスポータ / ヒスチジン残基 / 薬物送達システム / 頂側膜酵素 / DNA断片化 / 細胞障害 / ネクローシス / アポトーシス / シスプラチン / 薬剤性腎障害 / gabapentin / 電位依存性カルシウムチャネル / アミノ酸トランスポーター / ペプチドトランスポーター / TCA回路中間体 / Na+共役型ジ･トリカルボン酸トランスポーター / トランスポーター / アストロサイト / 中枢神経系 / エンケファリン輸送 / クエン酸回路 / 初代培養神経細胞 / 有機イオントランスポーター / 母集団解析 / 個別化投与設計 / 薬理ゲノム解析 / PK/PD解析 / 母集団薬物速度論 / 第Xa因子阻害薬 / cyclosoorine / tacrolimus / calcineurin / liver transplantation / transporter / drug metabolizing enzyme / absorptive barrier / immunosuppressant / 肝臓移植治療 / シクロスポリン / タクロリムス / カルシニューリン / 肝移植治療 / 薬物代謝酵素 / 吸収障壁 / 免疫抑制剤 / Organic ion / Renal excretion / Detoxification system / Expression profile / Genetic polymorphism / Interindividual differences / Personalized pharmacotherapy / Drug transporter / 遺伝子発現 / 腎疾患 / ペプチド類似薬物 / カチオン性薬物 / アニオン性薬物 / オーダーメイド薬物療法 / 有機イオン / 腎排泄 / 解毒システム / 固体間変動 / テーラーメイド薬物療法 / Drug interaction / Tubular secretion / Excretion / Kidney / 3級アミン交換輸送系 / H^+ / 性差 / CaCo^2細胞 / 排泄 / cDNA cloning / Xenopus oocyte / transfection / P-glycoprotein / organic cation transporter / organic ahion transporter / tubular secretion / drug transport / メトトレキセート / 動物細胞安定発現系 / アフリカメガユル卵母細胞 / P・糖タンパク質 / cDNAクローニング / アフリカツメガエル卵母細胞 / トランスフェクション / 有機カテオントランスポータ / Nonsteroidal anti-inflammatory drugs / Histidine tesidue / beta-L actam antibiotics / Peptide transporter / Stable transfectant / クローニング / 腸管吸収 / β-ランタム抗生物質 / 非ステロイド抗炎症薬 / β-ラクタム抗生物質 / 安定発現系 / 肝臓 / 小腸 / メタボリックシンドローム / メトホルミン / 核内受容体 / 転写因子 / 薬剤反応 / 薬学 / ヒト組織 / 細胞膜 / 極性上皮細胞 / 蛋白質間相互作用 / P-糖蛋白質 / 転写調節 / 薬物体内動態 / 側底膜 / 刷子縁膜 / 小腸上皮細胞 / LLC-PIC_1 / プロテインキナーゼC / キメラ / バラシクロビル / アシクロビル / LLC-PK_1 Less

直接作用型経口抗凝固薬の適正使用に向けた基盤構築Principal Investigator
- Principal Investigator
  
  桂敏也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Ritsumeikan University
Development of the prediction system for tubular secretion of drugs in the human kidneyPrincipal Investigator
- Principal Investigator
  
  Katsura Toshiya
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Ritsumeikan University
Comprehensive analysis between transporter-mediated tissue distribution of drugs and their toxicityPrincipal Investigator
- Principal Investigator
  
  KATSURA Toshiya
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Pharmacokinetic and pharmacodynamic analysis of oral direct inhibitors of activated coagulation factor X for application to individualized pharmacotherapy
- Principal Investigator
  
  Ueshima Satoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Biochemical properties of various organic ion transporters in central nervous system
- Principal Investigator
  
  FUJITA Takuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Development of in vitro model system to predict the renal secretion of drugs in human kidneyPrincipal Investigator
- Principal Investigator
  
  Katsura Toshiya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
腎排泄型カチオン性小分子の多階層的生体挙動制御解析Principal Investigator
- Principal Investigator
  
  桂敏也
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Elucidation of the physiological and pharmacokinetic significance of the renal drug excretion systemsPrincipal Investigator
- Principal Investigator
  
  KATSURA TOSHIYA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Ritsumeikan University
  Kyoto University
ヒト薬物トランスポートソームの発現プロファイル構築に基づく薬物動態学的意義の解明
- Principal Investigator
  
  乾賢一
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
PHARMACOKINETICS IN THE PATIENTS WITH METABOLIC SYNDROME AND APPLICATION FOR PHARMACOTHERAPY
- Principal Investigator
  
  INUI Ken-ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Identification of essential determinants for membrane localization of drug transporters and elucidation of their polarized transport mechanismsPrincipal Investigator
- Principal Investigator
  
  KATSURA Toshiya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
ペプチドトランスポートソームの実体解明と発現・局在調節における生理的意義
- Principal Investigator
  
  乾賢一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Elucidation of the cell-and organ-specific transport mechanisms of organic anion transportersPrincipal Investigator
- Principal Investigator
  
  KATSURA Toshiya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Establishment of personalized immunosuppressive therapy based on molecular mechanisms of transplant immunological network
- Principal Investigator
  
  INUI Ken-ichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
極性上皮細胞における有機イオントランスポータの細胞膜局在化機構の解明Principal Investigator
- Principal Investigator
  
  桂敏也
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
薬物トランスポータの発現量変動評価系の構築-薬物体内動態制御薬の開発へ向けて
- Principal Investigator
  
  乾賢一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
甲状腺疾患時における薬物トランスポータの発現変化と薬物体内動態変動Principal Investigator
- Principal Investigator
  
  桂敏也
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto University
Evaluation of drug interaction and interindividual differences of renal drug excretion based on the genetic polymorphism analysis
- Principal Investigator
  
  INUI Ken-ichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSTTY
薬物トランスポータの分子認識能に基づく薬物分子設計
- Principal Investigator
  
  乾賢一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
カチオン性薬物の消化管吸収機構の解明:輸送担体介在輸送の実証と遺伝子クローニングPrincipal Investigator
- Principal Investigator
  
  桂敏也
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
Molecular diversity of organic ion transporters and their roles in the renal drug excretion
- Principal Investigator
  
  INUI Ken-ichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
薬物トランスポータの分子認識能を利用した臓器特異的薬物送達システムの構築
- Principal Investigator
  
  乾賢一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
薬剤性腎障害におけるアポトーシス誘動と腎障害発現防御に関する研究
- Principal Investigator
  
  乾賢一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto University
腎尿細管上皮細胞における薬物輸送担体の細胞膜局在性と細胞膜ソーティング機構の解析Principal Investigator
- Principal Investigator
  
  桂敏也
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
薬剤性腎障害発現におけるアポトーシスの役割に関する研究
- Principal Investigator
  
  INUI Ken-ichi
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Development of novel systems for evaluation and prediction of drug inteactions based on the reconstruction of drug excretion systems in vitro.
- Principal Investigator
  
  INUI Ken-ichi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSITY
Molucular analysis of tissue distribution and structure-function relationship of transporters responsible for the regulation of drug transport
- Principal Investigator
  
  INUI Ken-ichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY

[Journal Article] Association of direct oral anticoagulant and delayed bleeding with pharmacokinetics after endoscopic submucosal dissection2024
- Author(s)
  Murata M, Sugimoto M, et al.
- Journal Title
  
  Gastrointest Endosc
  
  Volume: 99 Issue: 5 Pages: 721-732
- DOI
  10.1016/j.gie.2023.11.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07949, KAKENHI-PROJECT-23K06225
[Journal Article] Pharmacokinetic properties of CYP3A substrate midazolam associated with xenobiotic-mediated CYP induction in inflammation model mice.2024
- Author(s)
  Fujino C, Hayashi K, Kubo Y, Ueshima S, Katsura T.
- Journal Title
  
  BPB Reports
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06225
[Journal Article] Attenuation of phenobarbital‐induced cytochrome P450 expression in carbon tetrachloride‐induced hepatitis in mice models2023
- Author(s)
  Fujino Chieri、Kuzu Taiki、Kubo Yukine、Hayashi Kurumi、Ueshima Satoshi、Katsura Toshiya
- Journal Title
  
  Biopharmaceutics and Drug Disposition
  
  Volume: - Issue: 5 Pages: 351-357
- DOI
  10.1002/bdd.2356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06757, KAKENHI-PROJECT-23K06225
[Journal Article] Administration of zinc to preterm infants with hypozincemia does not reduce serum copper concentrations in most cases: a single-center retrospective observational study2021
- Author(s)
  Ito Toshikazu、Uenoyama Kazuya、Kobayashi Kazuhiro、Kakumoto Mikio、Mizumoto Hiroshi、Katsura Toshiya、Onoue Masahide
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 7 Issue: 1
- DOI
  10.1186/s40780-021-00229-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06766
[Journal Article] Variation in Expression of Cytochrome P450 3A Isoforms and Toxicological Effects: Endo- and Exogenous Substances as Regulatory Factors and Substrates2021
- Author(s)
  Fujino Chieri、Sanoh Seigo、Katsura Toshiya
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 11 Pages: 1617-1634
- DOI
  10.1248/bpb.b21-00332
- NAID
  130008110315
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-11-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06766
[Journal Article] Population pharmacokinetics and pharmacodynamics of apixaban linking its plasma concentration to intrinsic activated coagulation factor X activity in Japanese patients with atrial fibrillation2019
- Author(s)
  Ueshima Satoshi、Hira Daiki、Tomitsuka Chiho、Nomura Miki、Kimura Yuuma、Yamane Takuya、Tabuchi Yohei、Ozawa Tomoya、Itoh Hideki、Horie Minoru、Terada Tomohiro、Katsura Toshiya
- Journal Title
  
  The AAPS Journal
  
  Volume: 21 Issue: 5 Pages: 80-80
- DOI
  10.1208/s12248-019-0353-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06766, KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-17K09494, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17K15504
[Journal Article] Genetic variants of alcohol‐metabolizing enzymes in Brugada syndrome: Insights into syncope after drinking alcohol2019
- Author(s)
  Wu Qi、Hayashi Hideki、Hira Daiki、Sonoda Keiko、Ueshima Satoshi、Ohno Seiko、Makiyama Takeru、Terada Tomohiro、Katsura Toshiya、Miura Katsuyuki、Horie Minoru
- Journal Title
  
  Journal of Arrhythmia
  
  Volume: 35 Issue: 5 Pages: 752-759
- DOI
  10.1002/joa3.12227
- NAID
  120006848263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06766, KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17K15504
[Journal Article] Population pharmacokinetics and pharmacogenomics of apixaban in Japanese adult patients with atrial fibrillation.2018
- Author(s)
  Ueshima S, Hira D, Kimura Y, Fujii R, Tomitsuka C, Yamane T, Tabuchi Y, Ozawa T, Itoh H, Ohno S, Horie M, Terada T, Katsura T.
- Journal Title
  
  Br. J. Clin. Pharmacol.
  
  Volume: - Issue: 6 Pages: 1301-1312
- DOI
  10.1111/bcp.13561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15504, KAKENHI-PROJECT-17K15528, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-17K09494, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-18K06766, KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-15K08114
[Journal Article] Impact of ABCB1, ABCG2, and CYP3A5 polymorphisms on plasma trough concentrations of apixaban in Japanese patients with atrial fibrillation2017
- Author(s)
  Satoshi Ueshima, Daiki Hira, Ryo Fujii, Yuuma Kimura, Chiho Tomitsuka, Takuya Yamane, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Journal Title
  
  Pharmacogenetics and Genomics
  
  Volume: 27 Issue: 9 Pages: 329-336
- DOI
  10.1097/fpc.0000000000000294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08114, KAKENHI-PROJECT-17K09494, KAKENHI-PROJECT-17K15504, KAKENHI-PROJECT-17K15528, KAKENHI-PROJECT-15H04818
[Journal Article] オキサリプラチンによるアレルギーで中止後、再投与により薬剤誘発性血小板減少症に至った 1 症例2016
- Author(s)
  本多伸二、村田龍宣、三松史野、佐分利美帆子、楠川侑吾、目黒裕史、大野恵一、伊藤鉄夫、桂敏也、村岡淳二
- Journal Title
  
  医療薬学
  
  Volume: 42 Pages: 834-838
- NAID
  130006248722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08114
[Journal Article] Safety and efficacy of sustained release of basic fibroblast growth factor using gelatin hydrogel in patients with critical limb ischemia.2015
- Author(s)
  Kumagai M, Marui A, Tabata Y, Takeda T, Yamamoto M, Yonezawa A, Tanaka S, Yanagi S, Ito-Ihara T, Ikeda T, Murayama T, Teramukai S, Katsura T, Matsubara K, Kawakami K, Yokode M, Shimizu A, Sakata R.
- Journal Title
  
  Heart and Vessels
  
  Volume: 30 Issue: 5 Pages: 713-721
- DOI
  10.1007/s00380-015-0677-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670074, KAKENHI-PROJECT-15K08114, KAKENHI-PROJECT-25500003, KAKENHI-PROJECT-15K10241
[Journal Article] Sorafenib in a hepatocellular carcinoma patient with end-stage renal failure : A pharmacokinetic study2014
- Author(s)
  Ishii T, Hatano E, Taura K, Mizuno T, Kawai T, Fukudo M, Katsura T, Uemoto S
- Journal Title
  
  Hepatol. Res
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Investigation of endogenous compounds for assessing the drug interactions in the urinary excretion involving multidrug and toxin extrusion proteins2014
- Author(s)
  Kato K, Mori H, Kito T, Yokochi M, Ito S, Inoue K, Yonezawa A, Katsura T, Kumagai Y, Yuasa H, Moriyama Y, Inui K, Kusuhara H, Sugiyama Y
- Journal Title
  
  Pharm. Res
  
  Volume: 31 Pages: 136-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] The effect of ABCG2 genotype on the population pharmacokinetics of sunitinib in patients with renal cell carcinoma2014
- Author(s)
  Mizuno T, Fukudo M, Fukuda T, Terada T, Dong M, Kamba T, Yamasaki T, Ogawa O, Katsura T, Inui K, Vinks AA, Matsubara K.
- Journal Title
  
  Ther Drug Monit
  
  Volume: 36 Issue: 3 Pages: 310-316
- DOI
  10.1097/ftd.0000000000000025
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25136710, KAKENHI-PROJECT-25460187, KAKENHI-PROJECT-25670074
[Journal Article] Sorafenib in a hepatocellular carcinoma patient with end-stage renal failure: A pharmacokinetic study.2014
- Author(s)
  Ishii T, Hatano E, Taura K, Mizuno T, Kawai T, Fukudo M, Katsura T, Uemoto S.
- Journal Title
  
  Hepatology Research
  
  Volume: 44 Issue: 6 Pages: 685-688
- DOI
  10.1111/hepr.12156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138, KAKENHI-PROJECT-23659647, KAKENHI-PROJECT-25670074
[Journal Article] Investigation of endogenous compounds for assessing the drug interactions in the urinary excretion involving multidrug and toxin extrusion proteins.2014
- Author(s)
  Kato K, Mori H, Kito T, Yokochi M, Ito S, Inoue K, Yonezawa A, Katsura T, Kumagai Y, Yuasa H, Moriyama Y, Inui K, Kusuhara H, Sugiyama Y.
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 31 Issue: 1 Pages: 136-147
- DOI
  10.1007/s11095-013-1144-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390138, KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-25670074
[Journal Article] Population pharmacokinetics/pharmacodynamics of erlotinib and pharmacogenomic analysis of plasma and cerebrospinal fluid drug concentrations in Japanese patients with non-small cell lung cancer.2013
- Author(s)
  Fukudo M, Ikemi Y, Togashi Y, Masago K, Kim YH, Mio T, Terada T, Teramukai S, Mishima M, Inui K, Katsura T.
- Journal Title
  
  Clinical Pharmacokinetics
  
  Volume: 52 Issue: 7 Pages: 593-609
- DOI
  10.1007/s40262-013-0058-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138, KAKENHI-PROJECT-23790597, KAKENHI-PROJECT-25460187, KAKENHI-PROJECT-25670074
[Journal Article] Effect of P-glycoprotein and breast cancer resistance protein inhibition on the pharmacokinetics of sunitinib in rats.2013
- Author(s)
  Kunimatsu S, Mizuno T, Fukudo M, Katsura T.
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 41 Issue: 8 Pages: 1592-1597
- DOI
  10.1124/dmd.112.050286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138, KAKENHI-PROJECT-25670074
[Journal Article] Effect of P-glycoprotein and breast cancer resistance protein inhibition on the pharmacokinetics of sunitinib in rats2013
- Author(s)
  Kunimatsu S, Mizuno T, Fukudo M, Katsura T.
- Journal Title
  
  Drug Metab. Dispos
  
  Volume: 41 Pages: 1592-1597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Precise comparison of protein localization among OCT, OAT, and MATE in human kidney.2013
- Author(s)
  Motohashi H, Nakao Y, Masuda S, Katsura T, Kamba T, Ogawa O, Inui K.
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 102 Issue: 9 Pages: 3302-3308
- DOI
  10.1002/jps.23567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138, KAKENHI-PROJECT-23790182, KAKENHI-PROJECT-25460231, KAKENHI-PROJECT-25670074
[Journal Article] Population pharmacokinetics/pharmacodynamics of erlotinib and pharmacogenomic analysis of plasma and cerebrospinal fluid drug concentrations in Japanese patients with non-small cell lung cancer2013
- Author(s)
  Fukudo M, Ikemi Y, Togashi Y, Masago K, Kim YH, Mio T, Terada T, Teramukai S, Mishima M, Inui K, Katsura T
- Journal Title
  
  Clin. Pharmacokinet
  
  Volume: 52 Pages: 593-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Precise comparison of protein localization among OCT, OAT, and MATE in human kidney2013
- Author(s)
  Motohashi H, Nakao Y, Masuda S, Katsura T, Kamba T, Ogawa O, Inui K
- Journal Title
  
  J. Pharm. Sci
  
  Volume: 102 Pages: 3302-3308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis2012
- Author(s)
  Toyama K, Yonezawa A, Masuda S, Osawa R, Hosokawa M, Fujimoto S, Inagaki N, Inui K, Katsura T
- Journal Title
  
  Br. J. Pharmacol
  
  Volume: 166 Pages: 1183-1191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Renal tubular secretion of varenicline by multidrug and toxin extrusion (MATE) transporters2012
- Author(s)
  Kajiwara M, Masuda S, Watanabe S, Terada T, Katsura T, Inui K
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 27 Pages: 563-569
- NAID
  130004933508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer2012
- Author(s)
  Togashi Y, Masago K, Masuda S, Mizuno T, Fukudo M, Ikemi Y, Sakamori Y, Nagai H, Kim YH, Katsura T, Mishima M
- Journal Title
  
  Cancer Chemother. Pharmacol
  
  Volume: 70 Pages: 399-405
- NAID
  120004874020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Developmental expression of renal organic anion transporters in rat kidney and its effect on renal secretion of phenolsulfonphthalein2012
- Author(s)
  Nomura M, Motohashi H, Sekine H, Katsura T, Inui K
- Journal Title
  
  Am. J. Physiol. Renal Physiol
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Detection of 22 antiepileptic drugs by ultra-performance liquid chromatography coupled with tandem mass spectrometry applicable to routine therapeutic drug monitoring2012
- Author(s)
  Shibata M, Hashi S, Nakanishi H, Masuda S, Katsura T, Yano I
- Journal Title
  
  Biomed. Chromatogr
  
  Volume: 26 Pages: 1519-1528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Impact of genetic variation in breast cancer resistance protein (BCRP/ABCG2) on sunitinib pharmacokinetics2012
- Author(s)
  Mizuno T, Fukudo M, Terada T, Kamba T, Nakamura E, Ogawa O, Inui K, Katsura T
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 27 Pages: 631-639
- NAID
  130004933515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Efficacy of increased-dose erlotinib for central nervous system metastases in non-small cell lung cancer patients with epidermal growth factor receptor mutation2011
- Author(s)
  Togashi Y, Masago K, Fukudo M, Tsuchido Y, Okuda C, Kim YH, Ikemi Y, Sakamori Y, Mio T, Katsura T, Mishima M
- Journal Title
  
  Cancer Chemother. Pharmacol
  
  Volume: 68 Pages: 1089-1092
- NAID
  120003534363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Effects of metabolic acidosis on expression levels of renal drug transporters2011
- Author(s)
  Gaowa A, Motohashi H, Katsura T, Inui K
- Journal Title
  
  Pharm. Res
  
  Volume: 28 Pages: 1023-1030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390138
[Journal Article] Effects of metabolic acidosis on expression levels of renal drug transporters.2011
- Author(s)
  Gaowa A, Motohashi H, Katsura T, Inui K.
- Journal Title
  
  Pharm Res 28
  
  Pages: 1023-1030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] ABCG2 421C>A polymorphism and high exposure of sunitinib in a patient with renal cell carcinoma.2010
- Author(s)
  Mizuno T, Terada T, Kamba T, Fukudo M, Katsura T, Nakamura E, Ogawa O, Inui K.
- Journal Title
  
  Ann Oncol 21
  
  Pages: 1382-1383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Hepatitis C virus-related cirrhosis is a major determinant of the expression levels of hepatic drug transporters.2010
- Author(s)
  Ogasawara K, Terada T, Katsura T, Hatano E, Ikai I, Yamaoka Y, Inui K.
- Journal Title
  
  Drug Metab Pharmacokinet 25
  
  Pages: 190-199
- NAID
  10027582589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients.2010
- Author(s)
  Toyama K, Yonezawa A, Tsuda M, Masuda S, Yano I, Terada T, Osawa R, Katsura T, Hosokawa M, Fujimoto S, Inagaki N, Inui K.
- Journal Title
  
  Pharmacogenet Genomics 20
  
  Pages: 135-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.2010
- Author(s)
  Watanabe S, Tsuda M, Terada T, Katsura T, Inui K.
- Journal Title
  
  J Pharmacol Exp Ther 334
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity.2010
- Author(s)
  Nakamura T, Yonezawa A, Hashimoto S, Katsura T, Inui K.
- Journal Title
  
  Biochem Pharmacol 80
  
  Pages: 1762-1767
- NAID
  120002619612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain.2010
- Author(s)
  Yao Y, Yonezawa A, Yoshimatsu H, Masuda S, Katsura T, Inui K.
- Journal Title
  
  J Nutr 140
  
  Pages: 1220-1226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity2009
- Author(s)
  Kajiwara M, Terada T, Ogasawara K, Iwano J, Katsura T, Fukatsu A, Doi T, Inui K.
- Journal Title
  
  J.Hum.Genet. 54
  
  Pages: 40-46
- NAID
  10030728868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells2009
- Author(s)
  Tsuda M, Terada T, Ueba M, Sato T, Masuda S, Katsura T, Inui K.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 329
  
  Pages: 185-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin.2009
- Author(s)
  Tsuda M, Terada T, Mizuno T, Katsura T, Shimakura J, Inui K.
- Journal Title
  
  Mol Pharmacol 75
  
  Pages: 1280-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2.2009
- Author(s)
  Kimura N, Masuda S, Katsura T, Inui K.
- Journal Title
  
  Biochem Pharmacol 77
  
  Pages: 1429-1436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells.2009
- Author(s)
  Tsuda M, Terada T, Ueba M, Sato T, Masuda S, Katsura T, Inui K.
- Journal Title
  
  J Pharmacol Exp Ther 329
  
  Pages: 185-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Targeted disruption of the multidrug and toxin extrusion 1 (matel) gene in mice reduces renal secretion of metformin2009
- Author(s)
  Tsuda M, Terada T, Mizuno T, Katsura T, Shimakura J, Inui K.
- Journal Title
  
  Mol.Pharmacol. 75
  
  Pages: 1280-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Impact of regulatory polymorphisms in organic anion transporter genes in the human liver.2009
- Author(s)
  Aoki M, Terada T, Ogasawara K, Katsura T, Hatano E, Ikai I, Inui K.
- Journal Title
  
  Pharmacogenet Genomics 19
  
  Pages: 647-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity.2009
- Author(s)
  Kajiwara M, Terada T, Ogasawara K, Iwano J, Katsura T, Fukatsu A, Doi T, Inui K.
- Journal Title
  
  J Hum Genet 54
  
  Pages: 40-46
- NAID
  10030728868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.2008
- Author(s)
  Sato T, Masuda S, Yonezawa A, Tanihara Y, Katsura T, Inui K.
- Journal Title
  
  Biochem Pharmacol 76
  
  Pages: 894-903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney2008
- Author(s)
  Ogasawara K, Terada T, Motohashi H, Asaka J, Aoki M, Katsura T, Kamba T, Ogawa O, Inui K.
- Journal Title
  
  J.Hum.Genet. 53
  
  Pages: 607-614
- NAID
  10021249665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Inhibitory effect of zinc on the absorption of beta-lactam antibiotic ceftibuten via the peptide transporters in rats.2008
- Author(s)
  Okamura M, Terada T, Katsura T, Inui K.
- Journal Title
  
  Drug Metab Pharmacokinet 23
  
  Pages: 464-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Thyroid hormone regulates the expression and function of P-glycoprotein in Caco-2 cells.2008
- Author(s)
  Nishio N, Katsura T, Inui K.
- Journal Title
  
  Pharm Res 25
  
  Pages: 1037-1042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1.2008
- Author(s)
  Yonezawa A, Masuda S, Katsura T, Inui K.
- Journal Title
  
  Am J Physiol Cell Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Regulation of basal core promoter activity of human organic cation transporter 1 (OCT1/SLC22A1).2008
- Author(s)
  Kajiwara M, Terada T, Asaka J, Aoki M, Katsura T, Ikai I, Inui K.
- Journal Title
  
  Am.J.Physiol.Gastrointest. Liver Physiol. 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Adaptive responses of renal organic anion transporter 3 (OAT3) during cholestasis.2008
- Author(s)
  Chen J, Terada T, Ogasawara K, Katsura T, Inui K.
- Journal Title
  
  Am J Physiol Renal Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Kidney-specific expression of human organic cation transporter 2 (OCT2/SLC22A2) is regulated by DNA methylation.2008
- Author(s)
  Aoki M, Terada T, Kajiwara M, Ogasawara K, Ikai I, Ogawa O, Katsura T, Inui K.
- Journal Title
  
  Am J Physiol Renal Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Significance of organic cation transporter 3 (SLC22A3) expression for the cytotoxic effect of oxaliplatin in colorectal cancer.2008
- Author(s)
  Yokoo S, Masuda S, Yonezawa A, Terada T, Katsura T, Inui K.
- Journal Title
  
  Drug Metab Dispos 36
  
  Pages: 2299-2306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Regulation of basal core promoter activity of human organic cation transporter 1(OCT1/SLC22A1).2008
- Author(s)
  Kajiwara M, Terada T, Asaka J, Aoki M, Katsura T, Ikai I, Inui K.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Kidney-specific expression of human organic cation transporter 2 (OCT2/SLC22A2) is regulated by DNA methylation2008
- Author(s)
  Aoki M, Terada T, Kajiwara M, Ogasawara K, Ikai I, Ogawa O, Katsura T, Inui K.
- Journal Title
  
  Am.J.Physiol.Renal Physiol. 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney.2008
- Author(s)
  Ogasawara K, Terada T, Motohashi H, Asaka J, Aoki M, Katsura T, Kamba T, Ogawa O, Inui K.
- Journal Title
  
  J Hum Genet 53
  
  Pages: 607-614
- NAID
  10021249665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Regulatory mechanism governing the diurnal rhythm of intestinal H^+/peptide cotransporter 1 (PEPT1).2008
- Author(s)
  Saito H, Terada T, Shimakura J, Katsura T, Inui K.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249036
[Journal Article] Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE12008
- Author(s)
  Sato T, Masuda S, Yonezawa A, Tanihara Y, Katsura T, Inui K.
- Journal Title
  
  Biochem.Pharmacol. 76
  
  Pages: 894-903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Characterization of the basal promoter element of human organic cation transporter 2 gene2007
- Author(s)
  Asaka J, Terada T, Ogasawara K, Katsura T, Inui K.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 321
  
  Pages: 684-689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Pharmacokinetic significance of luminal multidrug and toxin extrusion 1 in chronic renal failure rats2007
- Author(s)
  Nishihara K, Masuda S, JiL, Katsura T, Inui K.
- Journal Title
  
  Biochem.Pharmacol. 73
  
  Pages: 1482-1490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Critical roles of Spl in gene expression of human and rat H+/organic cation antiporter MATE12007
- Author(s)
  Kajiwara M, Terada T, Asaka J, Ogasawara K, Katsura T, Ogawa O, Fukatsu A, Doi T, Inui K.
- Journal Title
  
  Am.J.Physiol.Renal Physiol. 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusion/H+-organic cation antiporters2007
- Author(s)
  Tanihara Y, Masuda S, Sato T, Katsura T, Ogawa O, Inui K.
- Journal Title
  
  Biochem.Pharmacol. 74
  
  Pages: 359-371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity2007
- Author(s)
  Yokoo S, Yonezawa A, Masuda S, Fukatsu A, Katsura T, Inui K.
- Journal Title
  
  Biochem.Pharmacol. 74
  
  Pages: 477-487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Journal Article] Identification of essential histidine and cysteine residues of the H+/organic cation antiporter multidrug and toxin extrusion (MATE)2007
- Author(s)
  Asaka J, Terada T, Tsuda M, Katsura T, Inui K.
- Journal Title
  
  Mol.Pharmacol. 71
  
  Pages: 1487-1493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590142
[Presentation] 排泄トランスポーターMRP2の発現低下に伴う薬物動態関連遺伝子の発現変動機構の解明2024
- Author(s)
  藤野智恵里、上島　智、桂　敏也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] 乳癌化学療法中にタクロリムス血中濃度変動が認められた1症例2024
- Author(s)
  野田明宏、森本奈緒美、星田唯史、藤原大一朗、眞下惠次、和田祥明、多喜和夫、田辺和史、鳥井雅恵、桂　敏也
- Organizer
  第45回日本病院薬剤師会近畿学術大会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] 医薬品副作用データベース (JADER) を用いたアトルバスタチンによる横紋筋融解症の発現に関連する併用薬の検討2024
- Author(s)
  岡田真依、小川慶子、藤野智恵里、田上愛花、野田歩美、河村陸斗、桂　敏也、細木るみこ
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] FAERSを用いたHMG-CoA還元酵素阻害薬による横紋筋融解症の発現に影響を与える薬剤及び原疾患の検討2024
- Author(s)
  福本真也、小川慶子、藤野智恵里、田上愛花、野田歩美、河村陸斗、桂　敏也、細木るみこ
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] 肝炎モデルマウスにおけるフェノバルビタールによるシトクロムP450発現誘導の変動要因解析2024
- Author(s)
  久保幸音、藤野智恵里、上島　智、桂　敏也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] Pharmacogenomic analysis of risk factors for bleeding events in Japanese patients with atrial fibrillation treated with apixaban2023
- Author(s)
  Sayana Matsuda, Satoshi Ueshima, Daiki Hira, Yohei Tabuchi, Tetsuichiro Isono, Tomoya Ozawa, Hideki Itoh, Shin-ya Morita, Yoshihisa Nakagawa, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics in Shizuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] ミダゾラムの代謝反応を利用したCYP3A5代謝能の個体差予測に関する検討2023
- Author(s)
  藤内海登、藤野智恵里、福井智里、林　紅瑠実、上島　智、桂　敏也
- Organizer
  医療薬学フォーラム2023/第31回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] 直接作用型経口抗凝固薬内服者における内視鏡的粘膜下層剥離術後出血の薬理学的予測因子の探索的研究2023
- Author(s)
  杉本光繁、上島　智、松田清那、平　大樹、寺田智祐、桂　敏也
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] 急性肝炎によるフェノバルビタール誘導性シトクロムP450発現の変動およびそのメカニズムに関する検討2023
- Author(s)
  久保幸音、藤野智恵里、上島　智、桂　敏也
- Organizer
  フォーラム2023衛星薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] HMG-CoA還元酵素阻害薬の副作用リスクを変動させる候補薬物によるOATPの輸送機能および発現の変動2023
- Author(s)
  中井笑美、藤野智恵里、河村陸斗、田上愛花、小川慶子、上島　智、細木るみ子、桂　敏也
- Organizer
  第73回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] 早期消化器癌患者におけるアピキサバンの薬物動態/薬力学/ゲノム薬理学的解析2023
- Author(s)
  松田清那、上島　智、平　大樹、石井和樹、村田雅樹、杉本光繁、寺田智祐、桂　敏也
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06225
[Presentation] 肝臓の炎症が薬物代謝酵素の発現誘導に及ぼす影響2022
- Author(s)
  葛生泰己、藤野智恵里、林　紅瑠実、上島　智、桂　敏也
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] ヒト正常近位尿細管細胞HK-2におけるHepatocyte Nuclear Factor発現の影響2022
- Author(s)
  田頭怜奈、結城詩央里、根来亮介、藤野智恵里、上島　智、藤田卓也、桂　敏也
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 薬物代謝酵素UGT1Aの発現低下が薬物トランスポーターの遺伝子発現に及ぼす影響2022
- Author(s)
  藤野智恵里、荒井理佐子、上島　智、桂　敏也
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 急性および慢性関節炎モデルマウスにおけるシトクロムP450の発現変動2022
- Author(s)
  林　紅瑠実、藤野智恵里、葛生泰己、上島　智、桂　敏也
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 直接作用型経口抗凝固薬の消化管出血リスクとPGx2021
- Author(s)
  上島　智、桂　敏也
- Organizer
  第42回日本臨床薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 関節炎モデルマウスにおける薬物代謝酵素および薬物トランスポーターの発現変動2021
- Author(s)
  藤野智恵里、上島　智、桂　敏也
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 排泄トランスポーターMRP2の発現低下が薬物代謝酵素の遺伝子発現に与える影響2021
- Author(s)
  藤野智恵里、上島　智、桂　敏也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 慢性関節炎モデルマウスにおけるシトクロムP450（CYP）の遺伝子発現変動2021
- Author(s)
  林　紅瑠実、藤野智恵里、上島　智、桂　敏也
- Organizer
  第71回日本薬学会関西支部大会・総会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] Impact of substrates and inhibitors of breast cancer resistance protein on apixaban pharmacokinetics in Japanese patients with atrial fibrillation2021
- Author(s)
  Satoshi Ueshima, Daiki Hira, Karin Hirata, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Yoshihisa Nakagawa, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  第31回日本医療薬学会年会 (International Poster Session)、
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] Population pharmacokinetics of edoxaban in Japanese patients with atrial fibrillation2021
- Author(s)
  Sayana Matsuda, Satoshi Ueshima, Daiki Hira, Rio Michihata, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Moritake Iguchi, Masaharu Akao, Satoshi Shizuta, Takeshi Makiyama, Yoshihisa Nakagawa, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  第15回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 心房細動患者におけるエドキサバンの母集団薬物動態/ゲノム薬理学的解析2020
- Author(s)
  上島　智、平　大樹、道籏梨央、田淵陽平、伊藤英樹、小澤友哉、中川義久、堀江　稔、寺田智祐、桂　敏也
- Organizer
  第30回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 第Xa因子阻害薬の臨床薬物動態/ゲノム薬理学的研究2020
- Author(s)
  上島　智、桂　敏也
- Organizer
  第15回トランスポーター研究会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] Population pharmacokinetics and pharmacogenomics of rivaroxaban in Japanese patients with atrial fibrillation2020
- Author(s)
  Satoshi Ueshima, Daiki Hira, Kenji Kuwata, Karin Hirata, Yohei Tabuchi, Hideki Itoh, Tomoya Ozawa, Yoshihisa Nakagawa, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  第30回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] Edoxaban blood concentrations vary considerably and correlate with anti-factor Xa activity in atrial fibrillation patients2020
- Author(s)
  Minoru Horie, Satoshi Ueshima, Daiki Hira, Toshiya Katsura, Tomohiro Terada, Kouichi Kato, Tomoya Ozawa, Hideki Itoh, Yohei Tabuchi, Miya Horie, Yoshihisa Nakagawa, Takeru Makiyama, Satoshi Shizuta, Asami Kashiwa, Takanori Aizawa, Takeshi Kimura, Moritake Iguchi, Masaharu Akao
- Organizer
  第84回日本循環器学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] アピキサバン内服患者における乳癌耐性タンパク質 (ABCG2) を介した薬物間相互作用に関する検討2019
- Author(s)
  平田華鈴、上島　智、平　大樹、田淵陽平、伊藤英樹、小澤友哉、中川義久、堀江　稔、寺田智祐、桂　敏也
- Organizer
  医療薬学フォーラム2019/第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] アミオダロンの代謝におけるCYP3A4/5の寄与に関する基礎的検討2019
- Author(s)
  岡　拓朗、上島　智、藤野智恵里、桂　敏也
- Organizer
  第69回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] Quantitative evaluation of the contribution of CYP3A4 and CYP3A5 to amiodarone pharmacokinetics in human from in vitro data2019
- Author(s)
  岡　拓朗、上島　智、藤野智恵里、桂　敏也
- Organizer
  日本薬物動態学会第34回年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] チカグレロルの代謝反応におけるCYP3A4/5の寄与に関する基礎的検討2019
- Author(s)
  横井一駿、上島　智、藤野智恵里、桂　敏也
- Organizer
  日本医療薬学会第3回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 心房細動患者におけるリバーロキサバンの母集団薬物動態解析2019
- Author(s)
  上島　智、平　大樹、桑田健司、平田華鈴、田淵陽平、伊藤英樹、小澤友哉、中川義久、堀江　稔、寺田智祐、桂　敏也
- Organizer
  第29回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] Association of genetic polymorphisms in drug transporters and enzymes with plasma concentrations of rivaroxaban in Japanese patients with atrial fibrillation2018
- Author(s)
  Satoshi Ueshima, Daiki Hira, Takuya Yamane, Kenji Kuwata, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  2018 International Meeting on 22nd Microsomes and Drug Oxidations and 33rd Japanese Society fot the Study of Xenobiotics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] Population pharmacokinetics and pharmacodynamics of apixaban in Japanese patients with atrial fibrillation2018
- Author(s)
  Satoshi Ueshima, Daiki Hira, Chiho Tomitsuka, Miki Nomura, Yuuma Kimura, Takuya Yamane, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Seiko Ohno, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] Population pharmacokinetics and pharmacodynamics of apixaban in Japanese patients with atrial fibrillation2018
- Author(s)
  Satoshi Ueshima, Daiki Hira, Chiho Tomitsuka, Miki Nomura, Yuuma Kimura, Takuya Yamane, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Seiko Ohno, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] Association of genetic polymorphisms in drug transporters and enzymes with plasma concentrations of rivaroxaban in Japanese patients with atrial fibrillation2018
- Author(s)
  Satoshi Ueshima, Daiki Hira, Takuya Yamane, Kenji Kuwata, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  2018 International Meeting on 22nd Microsomes and Drug Oxidations and 33rd Japanese Society fot the Study of Xenobiotics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] ヒト組織におけるグルクロン酸抱合反応を考慮したエンタカポンの生理学的薬物速度論解析2018
- Author(s)
  爲本雄太、上島智、宮川幸典、目片茉柚、桂敏也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] 生理学的薬物速度論に基づくエンタカポンの体内動態解析2018
- Author(s)
  爲本雄太、上島智、宮川幸典、目片茉柚、桂敏也
- Organizer
  日本医療薬学会第2回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] アミオダロンの代謝に及ぼす血液凝固第Xa因子阻害薬の影響2018
- Author(s)
  芝口　彩、上島　智、平田華鈴、平野尋大、桂　敏也
- Organizer
  日本医療薬学会第2回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] アミオダロンの代謝に及ぼす血液凝固第Xa因子阻害薬の影響2018
- Author(s)
  芝口彩、上島智、平田華鈴、平野尋大、桂敏也
- Organizer
  日本医療薬学会第2回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] リバーロキサバンの血中濃度と臨床検査値及び薬物動態関連遺伝子多型の相関解析2018
- Author(s)
  桑田健司、上島智、平大樹、山根拓也、田淵陽平、伊藤英樹、小澤友哉、堀江稔、寺田智祐、桂敏也
- Organizer
  日本医療薬学会第2回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] ヒト組織におけるグルクロン酸抱合反応を考慮したエンタカポンの生理学的薬物速度論解析2018
- Author(s)
  爲本雄太、上島　智、宮川幸典、目片茉柚、桂　敏也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] リバーロキサバンの血中トラフ濃度に及ぼす薬物動態関連遺伝子多型の影響2018
- Author(s)
  桑田健司、上島智、平大樹、山根拓也、芝口彩、田淵陽平、伊藤英樹、小澤友哉、堀江稔、寺田智祐、桂敏也
- Organizer
  医療薬学フォーラム2018/第26回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K06766
[Presentation] リバーロキサバンの血中トラフ濃度に及ぼす薬物動態関連遺伝子多型の影響2018
- Author(s)
  桑田健司、上島　智、平　大樹、山根拓也、芝口　彩、田淵陽平、伊藤英樹、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  医療薬学フォーラム2018/第26回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] リバーロキサバンの血中濃度と臨床検査値及び薬物動態関連遺伝子多型の相関解析2018
- Author(s)
  桑田健司、上島　智、平　大樹、山根拓也、田淵陽平、伊藤英樹、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  日本医療薬学会第2回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] 生理学的薬物速度論に基づくエンタカポンの体内動態解析2018
- Author(s)
  爲本雄太、上島　智、宮川幸典、目片茉柚、桂　敏也
- Organizer
  日本医療薬学会第2回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] 心房細動患者におけるアピキサバンの母集団薬物動態/薬力学的解析2017
- Author(s)
  上島　智、平　大樹、冨塚知歩、野村実希、木村悠馬、山根拓也、田淵陽平、伊藤英樹、大野聖子、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  第27回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] Population pharmacokinetics and pharmacogenomics of apixaban in Japanese patients2017
- Author(s)
  Satoshi Ueshima, Daiki Hira, Ryo Fujii, Yuuma Kimura, Chiho Tomitsuka, Takuya Yamane, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Seiko Ohno, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Organizer
  2017 American Association of Pharmaceutical Scientists Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] HK-2細胞における薬物トランスポーターの発現に対するDNAメチル化の寄与2017
- Author(s)
  原本真紀、小早川さやか、米丸英里、上島　智、桂　敏也
- Organizer
  日本医療薬学会第1回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] 心房細動患者におけるアピキサバンの母集団薬物動態解析2017
- Author(s)
  山根拓也、上島　智、平　大樹、木村悠馬、藤井　亮、冨塚知歩、田淵陽平、伊藤英樹、大野聖子、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  医療薬学フォーラム2017/第25回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] 腎有機カチオントランスポーターを介したメトホルミン輸送に及ぼす造影剤の影響2017
- Author(s)
  越智由紀子、緒方彰子、安藤夏未、上島　智、桂　敏也
- Organizer
  日本医療薬学会第1回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] 経口抗凝固薬の副作用と血中薬物濃度に及ぼす薬物動態関連遺伝子多型の影響2017
- Author(s)
  平　大樹、上島　智、伊藤英樹、小澤友哉、堀江　稔、桂　敏也、寺田智祐
- Organizer
  第33回滋賀医科大学シンポジウム
- Place of Presentation
  滋賀医科大学 (滋賀県大津市)
- Year and Date
  2017-02-21
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] アピキサバン服用患者における出血症状及び血中薬物濃度と薬物動態関連遺伝子多型の相関解析2017
- Author(s)
  上島　智、平　大樹、藤井　亮、木村悠馬、冨塚知歩、山根拓也、大野聖子、伊藤英樹、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  第2回黒潮カンファレンス
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] アピキサバンの代謝反応におけるCYP3A5の寄与に関する基礎的検討2017
- Author(s)
  元永　彩、上島　智、目片茉柚、加藤諭紀、桂　敏也
- Organizer
  日本医療薬学会第1回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] 日本人心房細動患者におけるアピキサバンの母集団薬物動態解析2017
- Author(s)
  上島　智、平　大樹、藤井　亮、木村悠馬、冨塚知歩、山根拓也、田淵陽平、小澤友哉、伊藤英樹、大野聖子、堀江　稔、寺田智祐、桂　敏也
- Organizer
  第11回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] アピキサバンの血中濃度と血液凝固活性に関する速度論的解析2016
- Author(s)
  冨塚知歩、上島　智、平　大樹、野村実希、木村悠馬、山根拓也、伊藤英樹、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  医療薬学フォーラム2016
- Place of Presentation
  ピアザ淡海 (滋賀県草津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] 有機カチオントランスポーターを介した薬物輸送に及ぼす5-HT<SUB>3</SUB>受容体拮抗薬の影響2016
- Author(s)
  野中千絵、林宏紀、小早川さやか、越智由紀子、上島智、桂敏也
- Organizer
  医療薬学フォーラム2016/第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  滋賀県立芸術劇場びわ湖ホール（滋賀県・大津市）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] アピキサバン服用患者における出血症状と血中薬物濃度に及ぼす薬物動態関連遺伝子多型の影響2016
- Author(s)
  上島智、平大樹、藤井亮、木村悠馬、冨塚知歩、山根拓也、伊藤英樹、小澤友哉、堀江稔、寺田智祐、桂敏也
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] アピキサバン服用患者における出血症状と血中薬物濃度に及ぼす薬物動態関連遺伝子多型の影響2016
- Author(s)
  上島智、平大樹、藤井亮、木村悠馬、冨塚知歩、山根拓也、伊藤英樹、小澤友哉、堀江稔、寺田智祐、桂敏也
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  国立京都国際会館 (京都府京都市)
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] アピキサバンの血中濃度と血液凝固活性に関する速度論的解析2016
- Author(s)
  冨塚知歩、上島智、平大樹、野村実希、木村悠馬、山根拓也、伊藤英樹、小澤友哉、堀江稔、寺田智祐、桂敏也
- Organizer
  医療薬学フォーラム2016/第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  滋賀県立芸術劇場びわ湖ホール（滋賀県・大津市）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] アピキサバンの血中トラフ濃度に及ぼす薬物動態関連遺伝子多型の影響2016
- Author(s)
  木村悠馬、上島　智、平　大樹、藤井　亮、冨塚知歩、山根拓也、伊藤英樹、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  医療薬学フォーラム2016
- Place of Presentation
  ピアザ淡海 (滋賀県草津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] 有機カチオントランスポーターを介した薬物輸送に及ぼす5-HT3受容体拮抗薬の影響2016
- Author(s)
  野中千絵、林　宏紀、小早川さやか、越智由紀子、上島　智、桂　敏也
- Organizer
  医療薬学フォーラム2016
- Place of Presentation
  ピアザ淡海 (滋賀県草津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] アピキサバンの血中トラフ濃度に及ぼす薬物動態関連遺伝子多型の影響2016
- Author(s)
  木村悠馬、上島智、平大樹、藤井亮、冨塚知歩、山根拓也、伊藤英樹、小澤友哉、堀江稔、寺田智祐、桂敏也
- Organizer
  医療薬学フォーラム2016/第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  滋賀県立芸術劇場びわ湖ホール（滋賀県・大津市）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] エンタカポンのグルクロン酸抱合反応における個体間変動の定量的評価2015
- Author(s)
  上島　智，宮川　幸典，目片　茉柚，桂　敏也
- Organizer
  第36回日本臨床薬理学会学術総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K08114
[Presentation] エンタカポンのグルクロン酸抱合反応における個体間変動の定量的評価2015
- Author(s)
  上島　智，宮川　幸典，目片　茉柚，桂　敏也
- Organizer
  第36回日本臨床薬理学会学術総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25670074
[Presentation] エンタカポンのグルクロン酸抱合反応における個体間変動の定量的評価2015
- Author(s)
  上島　智、宮川幸典、目片茉柚、桂　敏也
- Organizer
  第36回　日本臨床薬理学会学術総会
- Place of Presentation
  京王プラザホテル (東京都新宿区)
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] Role of MATE1 in Renal Excretion and Tissue Distribution of Cationic Drugs2014
- Author(s)
  Katsura T
- Organizer
  2nd International Symposium on Epithelial Barrier and Transport
- Place of Presentation
  立命館大学（滋賀県）
- Year and Date
  2014-11-01
- Invited
- Data Source
  KAKENHI-PROJECT-25670074
[Presentation] カチオン性薬物の体内動態と薬効・毒性発現におけるMATE1の役割2013
- Author(s)
  桂　敏也
- Organizer
  新学術領域研究「統合的多階層生体機能学領域の確立とその応用」第六回（平成24年度第二回）領域全体会議・研究報告会
- Place of Presentation
  沖縄科学技術大学院大学
- Year and Date
  2013-01-16
- Invited
- Data Source
  KAKENHI-PUBLICLY-23136507
[Presentation] Importance of MATE1 in Renal Excretion and Tissue Distribution of Cationic Drugs2012
- Author(s)
  Katsura T, et al
- Organizer
  1st HD Physiology International Symposium
- Place of Presentation
  東京大学、東京都(招待講演)
- Year and Date
  2012-01-21
- Data Source
  KAKENHI-PROJECT-23390138
[Presentation] Importance of MATE1 in renal excretion and tissue distribution of cationic drugs2012
- Author(s)
  Katsura T, et al
- Organizer
  1st HD Physiology International Symposium
- Place of Presentation
  東京大学(東京都文京区)
- Year and Date
  2012-01-21
- Data Source
  KAKENHI-PROJECT-23390138
[Presentation] Importance of MATE1 in Renal Excretion and Tissue Distribution of Cationic Drugs2012
- Author(s)
  Katsura T, et al
- Organizer
  1st HD Physiology International Symposium
- Place of Presentation
  東京大学、東京都(招待講演)
- Year and Date
  2012-01-21
- Data Source
  KAKENHI-PUBLICLY-23136507
[Presentation] 腎排泄型カチオン性小分子の多階層的生体挙動制御解析2011
- Author(s)
  桂敏也, 他
- Organizer
  平成23年度領域全体会議
- Place of Presentation
  大阪大学、大阪市(招待講演)
- Year and Date
  2011-06-20
- Data Source
  KAKENHI-PROJECT-23390138
[Presentation] 腎排泄型カチオン性小分子の多階層的生体挙動制御解析2011
- Author(s)
  桂敏也, 他
- Organizer
  平成23年度領域全体会議
- Place of Presentation
  大阪大学、大阪市(招待講演)
- Year and Date
  2011-06-20
- Data Source
  KAKENHI-PUBLICLY-23136507
[Presentation] Drug-drug interaction and its importance for the safe and effective pharmacotherapy2007
- Author(s)
  Katsura T, et al.
- Organizer
  4th World Conference on Drug Absorption, Transport and Delivery
- Place of Presentation
  Kanazawa, Japan
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590142
[Presentation] Transcriptional activation of MDR1 gene by thyroid hormone receptor2007
- Author(s)
  Toshiya Katsura, et. al.
- Organizer
  Pharmaceutical Sciences World Congress 2007
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2007-04-24
- Data Source
  KAKENHI-PROJECT-19590142

1. INUI Ken-ichi (70034030)

# of Collaborated Projects: 13 results

# of Collaborated Products: 22 results
2. SAITO Hideyuki (40225727)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. OKUDA Masahiro (70252426)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. MASUDA Satoshiro (90303825)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
5. TERADA Tomohiro (10324641)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
6. HASHIMOTO Yukiga (90228429)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. MOTOHASHI Hideyuki (30359822)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
8. Ueshima Satoshi (70734771)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
9. YONEZAWA Atsushi (90452341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
10. YANO Ikuko (50273446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. Horie Minoru (90183938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. Hira Daiki (50636959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. FUJITA Takuya (00247785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Ganapathy Vadivel

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松原和夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 杉本光繁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Katsura Toshiya 桂 敏也

桂 敏也 カツラ トシヤ

KATSURA Toshiya 桂 敏也

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直接作用型経口抗凝固薬の適正使用に向けた基盤構築Principal Investigator

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Development of the prediction system for tubular secretion of drugs in the human kidneyPrincipal Investigator

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Comprehensive analysis between transporter-mediated tissue distribution of drugs and their toxicityPrincipal Investigator

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Development of in vitro model system to predict the renal secretion of drugs in human kidneyPrincipal Investigator

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腎排泄型カチオン性小分子の多階層的生体挙動制御解析Principal Investigator

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Elucidation of the physiological and pharmacokinetic significance of the renal drug excretion systemsPrincipal Investigator

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Identification of essential determinants for membrane localization of drug transporters and elucidation of their polarized transport mechanismsPrincipal Investigator

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Elucidation of the cell-and organ-specific transport mechanisms of organic anion transportersPrincipal Investigator

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Katsura Toshiya 桂敏也

桂敏也カツラトシヤ

KATSURA Toshiya 桂敏也