Adachi Reiko 安達玲子

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ADACHI Reiko 安達玲子

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Researcher Number	10291113
Other IDs
External Links
Affiliation (Current)	2025: 国立医薬品食品衛生研究所, 生化学部, 室長
Affiliation (based on the past Project Information) *help	2015 – 2018: 国立医薬品食品衛生研究所, 生化学部, 室長 2006: 国立医薬品食品衛生研究所, 代謝生化学部, 室長 2004 – 2005: NIHS, Division of Biosignaling, Senior researcher, 代謝生化学部, 主任研究官 2003: 国立医薬品食品衛生研究所, 主任研究官 1997 – 1999: NIHS,Div.of Xenobiotic Metabolism and Disposition, Researcher, 代謝生化学部, 研究員
Review Section/Research Field	Principal Investigator Environmental and hygienic pharmacy / Biological pharmacy / Biological pharmacy Except Principal Investigator Eating habits / Biological pharmacy / Biological pharmacy
Keywords	Principal Investigator 経皮感作 / 食物アレルギー / 活性酸素産性 / 貪食 / U937細胞 / オプソニン化ザイモザン / U937 / c-Cbl / Lyn / siRNA … More / Srcファミリーチロシンキナーゼ / 情報伝達 / 食細胞 / 細胞内情報伝達 / 細胞骨格 / アンチセンスオリゴDNA / コフィリン / 白血球 … More Except Principal Investigator siRNA / コフィリン / 食細胞 / 簡易分析法 / オンサイト分析 / 食物アレルギー / PI3-kinase / Interleukin-8 / phosphorylation / cofilin / chemotaxis / HL-60 cell / neutrophil / PI3-キナーゼ / IL-8 / LIMキナーゼ / リン酸化 / 走化性 / 白血球 / HL-60細胞 / Translocation / Intracellular pH / Cytoskeleton / Superoxide / Okadaic acid / Opsonized zymosan / Phagocytes / Cofilin / オカダ酸 / F-アクチン / 細胞内pH変化 / 共焦点レーザー走査蛍光顕微鏡 / 細胞内pH / トランスロケーション / 脱リン酸化反応 / アクチン結合蛋白 / オプソニン化ザイモザン Less

Mechanism analysis of allergen skin sensitization in food allergy and search for marker moleculesPrincipal Investigator
- Principal Investigator
  
  Adachi Reiko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  National Institute of Health Sciences
Development of the simple and rapid detection method for food allergen
- Principal Investigator
  
  Sakai Shinobu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  National Institute of Health Sciences
食細胞活性化時の情報伝達・細胞応答の機構に関するRNA干渉法を用いた解析Principal Investigator
- Principal Investigator
  
  安達玲子
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
The roles of cofilin and LIM-kinase in chemotaxis of phagocytes
- Principal Investigator
  
  SUZUKI Kazuhiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
白血球の機能発現におけるコフィリンの役割に関するアンチセンス法による解析Principal Investigator
- Principal Investigator
  
  安達玲子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
Studies on roles of cofilin (actin/PIP2-binding protein) in activation of phagocytes
- Principal Investigator
  
  SUZUKI Kazuhiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences (NIHS)

All 2018 2017 2016 2015 2007 2005 2004 2003

All Journal Article Presentation Book

[Book] 食品衛生検査指針理化学編 2015: 第4章 -アレルギー物質-2015
- Author(s)
  手島玲子, 安達玲子, 酒井信夫
- Total Pages
  45
- Publisher
  公益社団法人日本食品衛生協会出版
- Data Source
  KAKENHI-PROJECT-15K00904
[Journal Article] Japanese Food Allergen Labeling Regulation: An Update2018
- Author(s)
  Shoji Masahiro、Adachi Reiko、Akiyama Hiroshi
- Journal Title
  
  Journal of AOAC International
  
  Volume: 101 Issue: 1 Pages: 8-13
- DOI
  10.5740/jaoacint.17-0389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08061
[Journal Article] Determining Food Allergens by Skin Sensitization in Mice.2018
- Author(s)
  Tamehiro N, Adachi R, Kimura Y, Sakai S, Teshima R, Kondo K
- Journal Title
  
  Curr Protoc Toxicol.
  
  Volume: 76 Issue: 1
- DOI
  10.1002/cptx.48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00907, KAKENHI-PROJECT-15K08061
[Journal Article] Food allergen analysis for processed food using a novel extraction method to eliminate harmful reagents for both ELISA and lateral-flow tests.2016
- Author(s)
  Ito K, Yamamoto T, Oyama Y, Tsuruma R, Saito E, Saito Y, Ozu T, Honjoh T, Adachi R, Sakai S, Akiyama H, Shoji M
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 408 Issue: 22 Pages: 5973-5984
- DOI
  10.1007/s00216-016-9438-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08061
[Journal Article] Lyn, one of the Src-family tyrosine kinases expressed in phagocytes, plays an important role in β2 integrin-signalling pathways in opsonized zymosan-activated macrophage-like U937 cells2007
- Author(s)
  R.Adachi, K.Suzuki
- Journal Title
  
  Cell Biochemistry and Function (in press)
- Data Source
  KAKENHI-PROJECT-16790075
[Journal Article] Cofilin plays a critical role in IL-8-dependent chemotaxis of neutrophilic HL-60 cells through changes in phosphorylation2007
- Author(s)
  A.Hirayama, R.Adachi, S.Otani et al.
- Journal Title
  
  Journal of Leukocyte Biology 81巻
  
  Pages: 720-728
- Data Source
  KAKENHI-PROJECT-16790075
[Journal Article] Indirubin, a Chinese anti-leukaemia drug, promotes neutrophilic differentiation of human myelocytic leukaemia HL-60 cells2005
- Author(s)
  K.Suzuki, R.Adachi, A.Hirayama et al.
- Journal Title
  
  British Journal of Haematology 130巻5号
  
  Pages: 681-690
- Data Source
  KAKENHI-PROJECT-16790075
[Journal Article] Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library2004
- Author(s)
  Kusui, K., Sasaki, H., Adachi, R., Matsui, S., Yamamoto, K., Yamaguchi, T., Kasahara, T., Suzuki.K.
- Journal Title
  
  Mol.Cell.Biochem. 262
  
  Pages: 187-193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Journal Article] Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library2004
- Author(s)
  Kusui, K., Sasaki, H., Adachi, R., Matsui, S., Yamamoto, K., Yamaguchi, T., Kasahara, T., Suzuki, K.
- Journal Title
  
  Mol.Cell.Biochem. 262
  
  Pages: 187-193
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Journal Article] Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library2004
- Author(s)
  K.Kusui, H.Sasaki, R.Adachi et al.
- Journal Title
  
  Molecular and Cellular Biochemistry 262巻
  
  Pages: 187-193
- Data Source
  KAKENHI-PROJECT-16790075
[Journal Article] Triphenyltin enhances the neutrophilic differentiation of promyelocytic HL-60 Cells2003
- Author(s)
  Watanabe, H., Adachi, R., Hirayama, A., Kasahara, T., Suzuki, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 306
  
  Pages: 26-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Journal Article] Bisphenol A significantly enhances the neutrohilic differentiation of prormyelocytic HL-60 cells2003
- Author(s)
  Watanabe, H., Adachi, R., Kusui, K., Hirayama, A., Kasahara, T., Suzuki, K.
- Journal Title
  
  Int.Immunopharmacol. 3
  
  Pages: 1601-1608
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Journal Article] 食細胞の機能発現とLIMキナーゼ-コフィリンによるアクチン細胞骨格制御2003
- Author(s)
  安達玲子, 鈴木和博
- Journal Title
  
  生化学 75
  
  Pages: 1238-1243
- NAID
  50000316593
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Journal Article] Bisphenol A significantly enhances the neutrohilic differentiation of promyelocytic HL-60 cells2003
- Author(s)
  Watanabe, H., Adachi, R., Kusui, K., Hirayama, A., Kasahara, T., Suzuki, K
- Journal Title
  
  Int.Immunopharmacol. 3
  
  Pages: 1601-1608
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Journal Article] Relationship between phagocyte functions and regulation of actin cytoskeleton by LIM-kinase and cofilin (Review in Japanese)2003
- Author(s)
  Adachi, R., Suzuki, K.
- Journal Title
  
  Seikagaku 75
  
  Pages: 1238-1243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Journal Article] Triphenyltin enhances the neutrophilic differentiation of promyelocytic HL-602003
- Author(s)
  Watanabe, H., Adachi, R., Hirayama, A., Kasahara, T., Suzuki, K
- Journal Title
  
  Biochem.Biophys.Res.Commun. 306
  
  Pages: 26-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590090
[Presentation] Enhancement of transdermal protein sensitization by titanium dioxide nanomaterials2018
- Author(s)
  Reiko Adachi, Norimasa Tamehiro, Shinobu Sakai, Yoshie Kimura, Hongyan Cui, Tomoko Nishimaki-Mogami, Kazunari Kondo
- Organizer
  57th SOT Annual Meeting & ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08061
[Presentation] Transcutaneous sensitization testing for food allergens2017
- Author(s)
  N. Tamehiro, R. Adachi, Y. Kimura, S. Sakai, R. Teshima, K. Kondo
- Organizer
  Society of Toxicology 56th Annual Meeting and ToxExpo
- Place of Presentation
  Baltimore, USA
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08061
[Presentation] ナノ酸化チタンの結晶構造の違いが抗原の経皮感作性に与える影響2017
- Author(s)
  為広紀正、安達玲子、木村美恵、酒井信夫、崔紅艶、最上(西巻)知子, 近藤一成
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15K08061
[Presentation] 酸加水分解コムギの脱アミド化エピトープを特異的に認識するモノクローナル抗体を用いた抗原性の解析2017
- Author(s)
  酒井信夫、田原麻衣子、中村里香、中村亮介、佐々木和実、西嶋桂子、安宅花子、沼田充、石井恭子、Tranquet O, Denery S, 中村政志、松永佳世子、手島玲子、安達玲子、五十嵐良明
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K08061
[Presentation] 酸加水分解コムギの脱アミド化エピトープを特異的に認識するモノクローナル抗体を用いた抗原性の解析2017
- Author(s)
  酒井信夫, 田原麻衣子, 中村里香, 中村亮介, 佐々木和実, 西嶋桂子, 安宅花子, T オリビエ, DP サンドラ, 佐藤奈由, 中村政志, 松永佳世子, 手島玲子, 安達玲子, 五十嵐良明
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K00904
[Presentation] 抗原感作に対する酸化チタンナノマテリアルの影響2016
- Author(s)
  安達玲子、木村美恵、酒井信夫、崔紅艶、最上(西巻)知子
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  名古屋
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K08061

1. SUZUKI Kazuhiro (10154527)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. Sakai Shinobu (60370938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. NAKAMURA Ryosuke (50333357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. KASAHARA Tadashi (60049096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAMEHIRO Norimasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Adachi Reiko 安達 玲子

ADACHI Reiko 安達 玲子

Research Projects

Research Products

Co-Researchers

Mechanism analysis of allergen skin sensitization in food allergy and search for marker moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the simple and rapid detection method for food allergen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

食細胞活性化時の情報伝達・細胞応答の機構に関するRNA干渉法を用いた解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of cofilin and LIM-kinase in chemotaxis of phagocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

白血球の機能発現におけるコフィリンの役割に関するアンチセンス法による解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on roles of cofilin (actin/PIP2-binding protein) in activation of phagocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 食品衛生検査指針 理化学編 2015: 第4章 -アレルギー物質-2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Japanese Food Allergen Labeling Regulation: An Update2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Determining Food Allergens by Skin Sensitization in Mice.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Food allergen analysis for processed food using a novel extraction method to eliminate harmful reagents for both ELISA and lateral-flow tests.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lyn, one of the Src-family tyrosine kinases expressed in phagocytes, plays an important role in β2 integrin-signalling pathways in opsonized zymosan-activated macrophage-like U937 cells2007

Author(s)

Journal Title

Data Source

[Journal Article] Cofilin plays a critical role in IL-8-dependent chemotaxis of neutrophilic HL-60 cells through changes in phosphorylation2007

Author(s)

Journal Title

Data Source

[Journal Article] Indirubin, a Chinese anti-leukaemia drug, promotes neutrophilic differentiation of human myelocytic leukaemia HL-60 cells2005

Author(s)

Journal Title

Data Source

[Journal Article] Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Ribosomal protein S18 identified as a cofilin-binding protein by using phage display library2004

Author(s)

Adachi Reiko 安達玲子

ADACHI Reiko 安達玲子

[Book] 食品衛生検査指針理化学編 2015: 第4章 -アレルギー物質-2015