Inoue Hiroki 井上弘樹

… Alternative Names

INOUE Hiroki 井上弘樹

井上弘樹イノウエヒロキ

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Researcher Number	10294448
Other IDs
External Links
Affiliation (Current)	2025: 東京薬科大学, 生命科学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 東京薬科大学, 生命科学部, 講師 2009 – 2016: Tokyo University of Pharmacy and Life Science, 生命科学部, 講師 2005: Osaka university, Graduate School of Science, Assistant Professor, 理学研究科, 助手 2004: 阪大, 理学(系)研究科(研究院), 助手 2001 – 2003: 大阪大学, 大学院・理学研究科, 助手 1999: 大阪大学, 大学院・理学研究科, 助手
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 43030:Functional biochemistry-related / Functional biochemistry Except Principal Investigator Basic Section 44010:Cell biology-related / Functional biochemistry / Biological Sciences / Structural biochemistry / Functional biochemistry
Keywords	Principal Investigator 小胞輸送 / 浸潤突起 / 転移 / 浸潤 / がん / アクチン / 微小管 / SNARE / エンドサイトーシス / 細胞骨格 … More / H.pylori / 大腸菌 / ナトリウムイオン / pH依存性 / イオン輸送 / NhaA / 増殖 / がん転移 / 浸潤転移 / アクチン線維 / 細胞外基質 / 浸潤性がん細胞 / MT1-MMP / 細胞外基質分解 / エンドソーム / 細胞膜 / 受容体輸送 / invadopodia / alpha-SNAP / g-SNAP / Rab11-FIP5 / KIAA0725p / DDHD2 / gamma-SNAP / トランスフェリン受容体 / 上皮成長因子受容体 / WAVE複合体 / Rab G protein / Arf G protein / ホスホリパーゼA1 / 膜輸送 / 膜輸送と輸送タンパク質 / 精製再構成 / システイン走査変異法 / 水素イオン / 分子生物学 / CHP2 / NHE / Nha1 / H^+交換輸送蛋白質 / Na^+ … More Except Principal Investigator Na^+ / 小胞体 / Na+ / ミトコンドリア / 遺伝子工学 / 膜蛋白質 / MAM / インフラマソーム / 脂肪滴 / オートファジー / syntaxin 17 / カルシューム結合蛋白 / イオン輸送分子機構 / H^+交換輸送 / 膜タンパクの細胞内局在化 / キメラ蛋白質の合成 / 膜蛋白質の精製と再構成 / 新規カルシューム結合性蛋白質 / pHセンサー / 能動輸送の分子機構 / イオン輸送蛋白質の構想と機能 / 分子遺伝学的アプローチ / 機能促進因子 / イオン輸送蛋白 / 生物学的統一性 / 能動輸送 / H^+交換輸送担体 / Na^+恒常性 / Cys走査変異解析 / FRET解析 / 能動透過系のエネルギー共役 / イオン輸送の分子機構 / 遺伝子解析 / H^+交換輸送蛋白質 / 細胞の塩環境適応 / イオン輸送 / CPT1a / カルジオリピン / リン酸化ー脱リン酸化 / リン酸化 / ラフト / マイトファジー / 脂肪適 / ACSL3 / 感染炎症 / gene engineering / Cys scanning mutagenesis / FRET analyses / bioenergetics of transporters / genetic and biochemical analyses / H+ antiporters / Molecular basis of ion transporters / Salinity torelance / Cys 走査変異解析 / Regulatory protein / Intracellular localization / Genetic approach / Active transport / Salt tolerance / Ion transport / H^+ antiporter / アポトーシスキナーゼ / 膜タンパク質 / 制御タンパク質 / 遺伝生化学 / エネルギー共役 / 塩耐性機構 / H^+交換輸送タンパク質 / molecular biological approach / intracellular localization of membrane proteins / molecular structure of membrane proteins / active transporters / salinity resistance / pH regulation / H+ exchangers / intracellular ion homeostasis / 細胞膜小胚輸送 / アポトーシスキナ-ゼ / ランダムミューテーション / 膜蛋白局在化 / 蛋白質工学 / 分子遺伝学 / 生体エネルギー共役 / 生物分子多様性 / 膜蛋白質のイオン透過機構 / 細胞内イオン恒常性 / 分子遺伝学的方法 / 膜蛋白質細胞内局在化機構 / 膜蛋白質構造 / 能動輸送機構 / 耐塩性 / pH調節 / H+交換輸送蛋白質 / 細胞内イオン環境 / 神経変性疾患 / レジオネラ / syntaxin17 / 膜輸送 / 蛋白質 / 組織・細胞 / モーター蛋白質 / 細胞内輸送 Less

Mechanism of how Stx17 changes its functions in response to nutrition status
- Principal Investigator
  
  TAGAYA MITSUO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tokyo Dental College
  Tokyo University of Pharmacy and Life Science
A study of membrane trafficking-cytoskeleton networks that promote cancer cell growth and metastasisPrincipal Investigator
- Principal Investigator
  
  井上弘樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
A crosstalk between membrane trafficking and cytoskeletons in invadopodia in cancer cellsPrincipal Investigator
- Principal Investigator
  
  Inoue Hiroki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Elucidation of the mechanism underlying the organization and multiple functions of the MAM
- Principal Investigator
  
  TAGAYA MITSUO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Identification of membrane fusion machineries for cancer cell invasionPrincipal Investigator
- Principal Investigator
  
  Inoue Hiroki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Roles of syntaxin 17 in the formation and function of the mitochondria-associated ER membrane
- Principal Investigator
  
  TAGAYA MITSUO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Molecular mechanisms of receptor trafficking by a phosphatidic acid-interacting Rab11 effector and their regulatorsPrincipal Investigator
- Principal Investigator
  
  INOUE Hiroki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
オルガネラ間相互作用を介したタンパク質の品質管理機構
- Principal Investigator
  
  TAGAYA Mitsuo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
Regulation of receptor trafficking and cytoskeleton by Arf small G proteins and their effectorsPrincipal Investigator
- Principal Investigator
  
  INOUE Hiroki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Na^+/H^+交換輸送蛋白質NhaAのpHセンサーおよびイオン交換輸送機構の解析Principal Investigator
- Principal Investigator
  
  井上弘樹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Adaptation of cells to high salinity conditions and basic mechanisms of ion transport in biological membranes
- Principal Investigator
  
  KANAZAWA Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Na^+/H^+交換輸送蛋白質NhaAのpHセンサー機構の解明Principal Investigator
- Principal Investigator
  
  井上弘樹
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Unity and diversity of ion transport mechanisms and regulation of Na+/H+ antiporters
- Principal Investigator
  
  KANAZAWA Hiroshi
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Structure, function and regulation of Na^+/H^+ antiporters and intracellular localization mechanism.
- Principal Investigator
  
  KANAZAWA Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Department of Biological Sciences, Graduate School of Science, Osaka University
生体膜蛋白質の細胞膜上の局在化に関与する新規システムの解明
- Principal Investigator
  
  KANAZAWA Hiroshi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University

[Book] The Structures and Functions of Intracellular Phospholipase A1 family proteins. In "Phospholipases in Health and Disease" Series : Advances in Biochemistry in Health and Disease2014
- Author(s)
  Tani, K., Baba, T. and Inoue, H.
- Publisher
  Springer Science, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23570174
[Book] The Structures and Functions of Intracellular Phospholipase A1 family proteins. In "Phospholipases in Health and Disease" Series: Advances in Biochemistry in Health and Disease2013
- Author(s)
  Tani, K., Baba, T. and Inoue, H.
- Total Pages
  13
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23570174
[Journal Article] A MAP1B?cortactin?Tks5 axis regulates TNBC invasion and tumorigenesis2024
- Author(s)
  Inoue Hiroki、Kanda Taku、Hayashi Gakuto、Munenaga Ryota、Yoshida Masayuki、Hasegawa Kana、Miyagawa Takuya、Kurumada Yukiya、Hasegawa Jumpei、Wada Tomoyuki、Horiuchi Motoi、Yoshimatsu Yasuhiro、Itoh Fumiko、Maemoto Yuki、Arasaki Kohei、Wakana Yuichi、Watabe Tetsuro、Matsushita Hiromichi、Harada Hironori、Tagaya Mitsuo
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 223 Issue: 3 Pages: 1-19
- DOI
  10.1083/jcb.202303102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06488, KAKENHI-PROJECT-21K07094, KAKENHI-PROJECT-22K19462, KAKENHI-PROJECT-19H04355, KAKENHI-PROJECT-23K21293, KAKENHI-PROJECT-23K24166
[Journal Article] The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER-Golgi membrane contact sites2021
- Author(s)
  Wakana Yuichi、Hayashi Kaito、Nemoto Takumi、Watanabe Chiaki、Taoka Masato、Angulo-Capel Jessica、Garcia-Parajo Maria F.、Kumata Hidetoshi、Umemura Tomonari、Inoue Hiroki、Arasaki Kohei、Campelo Felix、Tagaya Mitsuo
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 220 Issue: 1 Pages: 3355-3371
- DOI
  10.1083/jcb.202002150
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06562, KAKENHI-PUBLICLY-20H05520, KAKENHI-PLANNED-20H05772, KAKENHI-PROJECT-18H02656, KAKENHI-PROJECT-21H01968, KAKENHI-PROJECT-18K06138
[Journal Article] MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane.2019
- Author(s)
  Miyagawa, T.,* Hasegawa, K.,* Aoki, Y.,* Watanabe, T.,* Otagiri, Y., Arasaki, K., Wakana, Y., Asano, K., Tanaka, M., Yamaguchi, H., Tagaya, M. and Inoue, H. (*, These authors contributed equally to this work.)
- Journal Title
  
  J. Cell Biol.
  
  Volume: 218 Issue: 10 Pages: 3355-3371
- DOI
  10.1083/jcb.201808149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06138, KAKENHI-PROJECT-18K07219, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-18H02656, KAKENHI-PROJECT-17K07348, KAKENHI-PROJECT-17H04068
[Journal Article] MAP1B‐LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules2018
- Author(s)
  Arasaki Kohei、Nagashima Haruki、Kurosawa Yuri、Kimura Hana、Nishida Naoki、Dohmae Naoshi、Yamamoto Akitsugu、Yanagi Shigeru、Wakana Yuichi、Inoue Hiroki、Tagaya Mitsuo
- Journal Title
  
  EMBO reports
  
  Volume: 19 Issue: 8
- DOI
  10.15252/embr.201745584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06138, KAKENHI-PROJECT-18H02439, KAKENHI-PROJECT-18H02656
[Journal Article] Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy2018
- Author(s)
  Sugo Masashi、Kimura Hana、Arasaki Kohei、Amemiya Toshiki、Hirota Naohiko、Dohmae Naoshi、Imai Yuzuru、Inoshita Tsuyoshi、Shiba‐Fukushima Kahori、Hattori Nobutaka、Cheng Jinglei、Fujimoto Toyoshi、Wakana Yuichi、Inoue Hiroki、Tagaya Mitsuo
- Journal Title
  
  The EMBO Journal
  
  Volume: 37 Issue: 21
- DOI
  10.15252/embj.201798899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06138, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05902, KAKENHI-PROJECT-18H04023, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-17H04049, KAKENHI-PROJECT-18H02439, KAKENHI-PROJECT-18H02656
[Journal Article] Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 172017
- Author(s)
  Arasaki, K., Mikami, Y. Shames, S., Inoue, H., Wakana, Y. and Tagaya, M.
- Journal Title
  
  Nat. Commun.
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440064
[Journal Article] SNARE-associated proteins and receptor trafficking.2016
- Author(s)
  Inoue, H., Tani, K. and Tagaya, M.
- Journal Title
  
  Receptors & Clin. Investg.
  
  Volume: 3
- DOI
  10.14800/rci.1377
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440064
[Journal Article] A Role for the Ancient SNARE Syntaxin 17 in Regulating Mitochondrial Division2015
- Author(s)
  K. Arasaki, H. Shimizu, H. Mogari, N. Nishida, N. Hirota, A. Furuno, Y. Kudo, M. Baba, N. Baba, J. Cheng, T. Fujimoto, N.Ishihara, C. Ortiz-Sandoval, L. Barlow, A Raturi, N. Dohmae, Y. Wakana, H. Inoue, K.Tani, J. Dacks, T.Simmen, M. Tagaya
- Journal Title
  
  Developmental Cell
  
  Volume: 32(9) Issue: 3 Pages: 304-317
- DOI
  10.1016/j.devcel.2014.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510156, KAKENHI-PROJECT-24570076, KAKENHI-PROJECT-25291029, KAKENHI-PROJECT-26440064, KAKENHI-PROJECT-26440105, KAKENHI-PUBLICLY-26111522
[Journal Article] γ-SNAP stimulates disassembly of endosomal SNARE complexes and regulates endocytic trafficking pathways.2015
- Author(s)
  Inoue, H., Matsuzaki, Y., Tanaka, A., Hosoi, K., Ichimura, K., Arasaki, K., Wakana, Y., Asano, K., Tanaka, M., Okuzaki, D., Yamamoto, A., Tani, K. and Tagaya, M.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 128 Pages: 2781-2794
- DOI
  10.1242/jcs.158634
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440064, KAKENHI-PROJECT-15K18507, KAKENHI-PLANNED-26110006, KAKENHI-PUBLICLY-26111520, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-26713016, KAKENHI-PROJECT-26440105, KAKENHI-PROJECT-25291029
[Journal Article] The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.2015
- Author(s)
  Sekino, S., Kashiwagi, Y., Kanazawa, H., Takada, K., Baba, T., Sato, S., Inoue, H., Kojima, M. and Tani, K.
- Journal Title
  
  Cell Commun. Signal.
  
  Volume: 13 Issue: 1 Pages: 41-41
- DOI
  10.1186/s12964-015-0119-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440064, KAKENHI-PROJECT-26440105
[Journal Article] CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface.2015
- Author(s)
  Wakana Y., Kotake R., Oyama N., Murate M., Kobayashi T., Arasaki K., Inoue H., Tagaya M.
- Journal Title
  
  Mol. Biol Cell
  
  Volume: 26 Issue: 25 Pages: 4686-4699
- DOI
  10.1091/mbc.e15-08-0599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08167, KAKENHI-PROJECT-26440064, KAKENHI-PROJECT-15K18507, KAKENHI-PUBLICLY-26111520, KAKENHI-PROJECT-26650066, KAKENHI-PROJECT-26713016
[Journal Article] Moonlighting functions of the NRZ (mammalian Dsl1) complex. Front2014
- Author(s)
  Tagaya, M., Arasaki, K., Inoue, H., and Kimura, H.
- Journal Title
  
  Cell Develop. Biol
  
  Volume: (in press) Pages: 25-25
- DOI
  10.3389/fcell.2014.00025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24657141, KAKENHI-PROJECT-25291029, KAKENHI-PROJECT-26440064
[Journal Article] Valosin-containing protein-interacting membrane protein (VIMP) links the endoplasmic reticulum with microtubules in concert with cytoskeleton-linking membrane protein (CLIMP)-632014
- Author(s)
  Noda, C., Kimura, H., Arasaki, K., Matsushita, M., Yamamoto, A., Wakana, Y., Inoue, H., and Tagaya, M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Issue: 35 Pages: 24304-24313
- DOI
  10.1074/jbc.m114.571372
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25291029, KAKENHI-PROJECT-26440064
[Journal Article] A new role for RINT-1 in SNARE complex assembly at the trans-Golgi network in coordination with the COG complex.2013
- Author(s)
  A new role for RINT-1 in SNARE complex assembly at the trans-Golgi network in coordination with the COG complex.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 24 Issue: 18 Pages: 2907-2917
- DOI
  10.1091/mbc.e13-01-0014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570149, KAKENHI-PROJECT-23570174, KAKENHI-PROJECT-24790425, KAKENHI-PROJECT-25291029, KAKENHI-PROJECT-25840042
[Journal Article] Roles of SAM and DDHD domains in mammalian intracellular phospholipase A1 KIAA0725p2012
- Author(s)
  Inoue, H., Baba, T., Sato, S., Ohtsuki, R., Takemori, A., Watanabe, T., Tagaya, M., and Tani, K.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1823 (*, These authors contributed equally to this work.) Issue: 4 Pages: 930-939
- DOI
  10.1016/j.bbamcr.2012.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570174, KAKENHI-PROJECT-23570239
[Journal Article] The intracellular phospholipase A1 protein family2012
- Author(s)
  Tani, K., Kogure, T., and Inoue, H.
- Journal Title
  
  Biomol. Concepts
  
  Volume: 3 Issue: 5 Pages: 471-478
- DOI
  10.1515/bmc-2012-0014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570174, KAKENHI-PROJECT-23570239, KAKENHI-PROJECT-24657141
[Journal Article] Golgi-localized KIAA0725p regulates membrane trafficking from the Golgi apparatus to the plasma membrane in mammalian cells.2010
- Author(s)
  Sato, S., Inoue, H., Kogure, T., Tagaya, M., Tani, K.
- Journal Title
  
  FEBS lett.
  
  Volume: 584 Pages: 4389-4395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770150
[Journal Article] Golgi-localized KIAA0725p regulates membrane trafficking from the Golgiapparatus to the plasma membrane in mammalian cells.2010
- Author(s)
  Sato, S.,^* Inoue, H.,^* Kogure, T., Tagaya, M., Tani, K.(^*, These authors contributed equally to this work.)
- Journal Title
  
  FEBS lett. 584
  
  Pages: 4389-4395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770150
[Journal Article] Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4.2009
- Author(s)
  Mazelova, J., Astuto-Gribble, L., Inoue, H., Tam, B.M., Schonteich, E., Prekeris, R., Morit,z O.L., Randazzo, P.A., Deretic, D.
- Journal Title
  
  EMBO J. 28
  
  Pages: 183-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770150
[Journal Article] Detection of an oligomer formation and conformational change of Na^+/H^+ antiporter from Helicobacter pylori by fluorescence resonance energy transfer analysis2005
- Author(s)
  Akira Karasawa, Yumi Tsuboi, Hiroki Inoue, Rie Kinoshita, Norihiro Nakamura, Hiroshi Kanazawa
- Journal Title
  
  J. Biol Cem. 280
  
  Pages: 41900-41911
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] A novel kinesin-like protein, KIF1Bb3, is involved in the movement of lysosomes to the cell2004
- Author(s)
  Masafumi Matsushita, Shingo Tanaka, Norihiro Nakamura, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  traffic 5.1
  
  Pages: 140-151
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] The Fourth Transmembrane Segment of Helicobacter pylori Na^+/H^+ Antiporter NhaA Faces a Water-filled Channel Required for Ion Transport2004
- Author(s)
  Naoyuki Kuwabara, Hiroki Inoue, Yumi Tsuboi, Norihiro Nakamura, Hiroshi Kanazawa
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 40567-40575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] A conserved domain in the tail region of the Saccharomyces cerevisiae Na^+/H^+ antiporter (Nhalp) plays important roles in localization and salinity-resistant cell-growth2004
- Author(s)
  Keiji Mitsui, Shinya Kamauchi, Norihiro Nakamura, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  J. Biol. chem. 135
  
  Pages: 139-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] A novel kinesin-like protein, KIF1B□3, is involved in the movement of lysosomes to the cell periphery in non-neuronal cells2004
- Author(s)
  Masafumi Matsushita, Shingo Tanaka, Norihiro Nakamura, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  Traffic 5
  
  Pages: 140-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] The Fourth Transmembrane Segment of Helicobacter pylori Na^+/H^+ Antiporter NhaA Faces a Water-filled Channel Required for Ion Transport2004
- Author(s)
  Naoyuki Kuwabara, Hiroki Inoue, Yumi Tsuboi, Norihiro Nakamura, Hiroshi Kanazawa
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 40567-40575
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] A novel membrane protein capable of binding the Na^+/H^+ antiporter (Nha1p) enhances the salinity-resistant cell growth of Saccharomyces cerevisiae2004
- Author(s)
  Keiji Mitsui, Fumihiro Ochi, Norihiro Nakamura, Yoshihide Doi, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 12438-12447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] A novel membrane protein capable of binding the Na^+/H^+ antiporter (Nha1p) enhances the salinity-resistant cell growth of Saccharomyces cerevisiae2004
- Author(s)
  Keiji Mitsui, Fumihiro Ochi, Norihiro Nakamura, Yoshihide Doi, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 12438-12447
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] A novel kinesin-like protein, KIF1Bb3, is involved in the movement of lysosomes to the cell periphery in non-neuronal cells2004
- Author(s)
  Masafumi Matsushita, Shingo Tanaka, Norihiro Nakamura, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  Traffic 5
  
  Pages: 140-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] A conserved domain in the tail region of the Saccharomyces cerevisiae Na^+/H^+antiporter (Nha1p) plays important roles in localization and salinity-resistant cell-growth2004
- Author(s)
  Keiji Mitsui, Shinya Kamauchi, Norihiro Nakamura, Hiroki Inoue, Hiroshi Kanazwa
- Journal Title
  
  J.Biochem. 135
  
  Pages: 139-148
- NAID
  10016197869
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] A conserved domain in the tail region of the Saccharomyces cerevisiae Na^+/H^+ antiporter (Nha1p) plays important roles in localization and salinity-resistant cell-growth2004
- Author(s)
  Keiji Mitsui, Shinya Kamauchi, Norihiro Nakamura, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  J.Biochem. 135
  
  Pages: 139-148
- NAID
  10016197869
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Identification of membrane domains of Na^+/H^+ antiporter (NhaA) from Helicobacter pylorirequired for ion transport and pH sensing2003
- Author(s)
  Yumi Tsuboi, Hiroki Inoue, Norihiro Nakamuara, Hiroshi Kanazawa
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 21467-21473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] The apoptosis-inducing protein kinase DRAK2 is inhibited in a calcium-dependent manner by the calcium-binding protein CHP2003
- Author(s)
  Hiroshi Kuwahara, Junichi Kamei, Norihiro Nakamura, Miho Matsumoto, Hiroski, Inoue, Hiroshi Kanazawa
- Journal Title
  
  J.Biochem. 134
  
  Pages: 245-250
- NAID
  10012056944
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Two nuclear export signals specify the cytoplasmic localization of calcineurin B homologous protein 12003
- Author(s)
  Mana Nagaita, Hiroki Inoue, Norihiro Nakamura, Hiroshi Kanazawa
- Journal Title
  
  J.Biochem. 134
  
  Pages: 919-925
- NAID
  10012060182
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium2003
- Author(s)
  H.Inoue, Y.Nakamura, M.Nagita, T.Takai, M.Masuda, N.Nakamura, H.Kanazawa
- Journal Title
  
  Bull.Pharm.Bull. 26
  
  Pages: 148-155
- NAID
  110003608393
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Two nuclear export signals specify the cytoplasmic localization of calcineurin B homologous protein 12003
- Author(s)
  Mana Nagaita, Hiroki Inoue, Norihiro Nakamura, Hiroshi Kanazawa
- Journal Title
  
  J.Biohcem. 134
  
  Pages: 919-925
- NAID
  10012060182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Two nuclear export signals specify the cytoplasmic localization of calcineurin B homologous protein 12003
- Author(s)
  Mana Nagita, Hiroki Inoue, Norihiro Nakamura, Hiroshi Kanazawa
- Journal Title
  
  J. Biochem. 134
  
  Pages: 919-925
- NAID
  10012060182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] The apoptosis-inducing protein kinase DRAK2 is inhibited in a calcium-dependent manner by the calcium-binding protein CHP2003
- Author(s)
  Hiroshi Kuwahara, Junichi Kamei, Norihiro Nakamura, Miho Matsumoto, Hiroki Inoue, Hiroshi Kanazawa
- Journal Title
  
  J. Biochem. 134
  
  Pages: 245-250
- NAID
  10012056944
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] Identification of membrane domains of Na^+/H^+ antiporter (NhaA) from Helicobacter pylori required for ion transport and pH sensing2003
- Author(s)
  Yumi Tsuboi, Hiroki Inoue, Norihiro Nakamuara, Hiroshi Kanazawa
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 21467-21473
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers- biding protein, is expressed in intestinal epithelium2003
- Author(s)
  H.Inoue, Y.Nakamura, M.Nagita, I.Takai, M.Masuda, N.Nakamura, H.Kanazawa
- Journal Title
  
  Bull.Pharm.Bull. 26
  
  Pages: 148-155
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] The apoptosis-inducing protein kinase DRAK2 is inhibited in a calcium-dependent manner by the calcium-binding protein CHP.2003
- Author(s)
  Hiroshi Kuwahara, Junichi Kamei, Norihiro Nakamura, Miho Matsumoto, Hiroki, Inoue
- Journal Title
  
  J.Biochem. 134
  
  Pages: 245-250
- NAID
  10012056944
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Identification of membrane domains of Na^+/H^+ antiporter (NhaA) from Helicobacter pylori required for ion transport and pH sensing2003
- Author(s)
  Yumi Tsuboi, Hiroki Inoue, Norihiro Nakamura, Hiroshi Kanazawa
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 21467-21473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370054
[Journal Article] Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-biding protein, is expressed in intestinal epithelium2003
- Author(s)
  H.Inoue, Y.Nakamura, M.Nagita, T.Takai, M.Masuda, N.Nakamura, H.Kanazawa
- Journal Title
  
  Bull. Pharm. Bull. 26
  
  Pages: 148-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers- biding protein, is expressed in intestinal epithelium2003
- Author(s)
  H.Inoue, Y.
- Journal Title
  
  Bull.Pharm.Bull. 26
  
  Pages: 148-155
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] KIF1Bb2, capable of interacting with CHP, is localized ti synaptic Vesicles2002
- Author(s)
  N.Nakamura, Y.Miyake, M.Matsushita, S.Tanaka, H.Inoue, H.Kanazawa
- Journal Title
  
  J. Biochem. 132
  
  Pages: 483-491
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] Structurally and functionally conserved domains in the diverse hydrophilic carboxy-terminal halves of various yeast and fungal Na+/H+ antiporters (Nhalp)2002
- Author(s)
  Kamauchi S., Mitsui, K., Ujike, S., Haga, M., Nakamura, N., Inoue, H., Sakajo, S., Ueda, M., Tanaka, A., Kanazawa, H.
- Journal Title
  
  J. Biochem. 131
  
  Pages: 821-831
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] A serine/threonine kinase which causes apoptosis like cell death interacts with a calcineurin B like protein capable of binding Na+ / H+ exchanger 12001
- Author(s)
  Matsumoto, M., Miyake, Y., Nagita, M., Inoue, H., Shitakubo, D., Takemoto, K., Ohtsuka, C., Nakamura, N., Kanazawa, H.
- Journal Title
  
  J. Biochem 130
  
  Pages: 217-225
- NAID
  50000907857
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] Chimeric Na+/H+ antiporters of NhaA from Helicobacter pylori and Escherichia coli : Implications for domains of NhaA for pH sensing2001
- Author(s)
  Inoue, H., Tsuboi, Y., Kanazawa H.
- Journal Title
  
  J. Biochem. 129
  
  Pages: 569-576
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] Chimeric Na^+/H^+ antiporters of NhaA from Helicobacter pylori and Escherichia coli : Implications for domains of NhaA for pH sensing2001
- Author(s)
  Inoue, H., Tsuboi, Y.
- Journal Title
  
  J.Biochem 129
  
  Pages: 569-576
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Journal Article] The murine genome contains one functional gene and two pseudogenes coding for the 16 kDa proteolipid subunit of vacuolar H+-ATPase2001
- Author(s)
  Keiko Hayami, Takato Noumi, Hiroki Inoue, Ge-Hong Sun-Wada, Takao Yoshimizu, Hiroshi Kanazawa
- Journal Title
  
  Gene 273
  
  Pages: 199-206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142207
[Presentation] トリプルネガティブ乳がんにおける微小管結合タンパク質による浸潤突起形成制御2023
- Author(s)
  井上弘樹，吉田正行，吉松康裕，伊東史子，前本佑樹，新崎恒平，若菜裕一，渡部徹郎，松下弘通，原田浩徳，多賀谷光男
- Organizer
  第８２回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21293
[Presentation] 微小管と接着因子複合体による浸潤突起の制御2023
- Author(s)
  和田朋之，井上弘樹，多賀谷光男
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21293
[Presentation] 微小管－アクチン結合タンパク質による浸潤突起の制御2023
- Author(s)
  井上弘樹，多賀谷光男
- Organizer
  第96回日本生化学会年会，2023年11月
- Data Source
  KAKENHI-PROJECT-23K21293
[Presentation] 浸潤突起形成因子Tks5と微小管の相互作用2020
- Author(s)
  神田拓，林楽人，多賀谷光男，井上弘樹
- Organizer
  第93回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-18K06138
[Presentation] Bet1は浸潤性乳がん細胞においてコレステロール依存的にMT1-MMPと相互作用し、細胞外基質分解を促進する2019
- Author(s)
  井上弘樹
- Organizer
  第２３回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06138
[Presentation] MT1-MMPは浸潤性乳がん細胞においてER-Golgi SNARE Bet1と相互作用し、Bet1をエンドソームにリクルートする2018
- Author(s)
  小田切ゆか，長谷川花奈，多賀谷光男，井上弘樹
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-18K06138
[Presentation] 毛細胆管形成におけるRab11-FIPsの機能2015
- Author(s)
  細井香里，舘野祐太，多賀谷光男，井上弘樹
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440064
[Presentation] SNAREタンパク質Bet1は浸潤突起へのMT1-MMPの効率的な輸送に必要である2015
- Author(s)
  宮川拓也，青木瑶子，渡邉卓也，山口英樹，多賀谷光男，井上弘樹
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440064
[Presentation] 浸潤突起形成に関わるSNAREタンパク質の探索2013
- Author(s)
  青木瑶子、渡邉卓也、多賀谷光男、井上弘樹
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25291029
[Presentation] γ-SNAPの結合因子と細胞内小胞輸送における機能2012
- Author(s)
  松崎友香,田中理華,渡邉卓也,井上弘樹,奥崎大介,多賀谷光男
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23570174
[Presentation] g-SNAPの結合因子と細胞内小胞輸送における機能2012
- Author(s)
  松崎友香，田中理華，渡邉卓也，井上弘樹，奥崎大介，多賀谷光男
- Organizer
  日本生化学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23570174
[Presentation] 細胞内型ホスホリパーゼA1のSAM-DDHDドメインはホスファチジルイノシトールリン酸の結合とホスホリパーゼA1活性に必須の領域である2011
- Author(s)
  竹森亜弥，井上弘樹，他
- Organizer
  日本生化学会第８４回大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23570174
[Presentation] 細胞内型ホスホリパーゼA1のSAM-DDHDドメインはホスファチジルイノシトールリン酸の結合とホスホリパーゼA1活性に必須の領域である2011
- Author(s)
  竹森亜弥,井上弘樹,馬場崇,大槻竜也,渡邉卓也,多賀谷光男,谷佳津子
- Organizer
  第84回日本生化学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23570174
[Presentation] KIAA0725p/DDHD2, a mammalian Golgi-associated phospholipase A1, regulates membrane trafficking from the Golgi apparatus to the plasma membrane.2010
- Author(s)
  Inoue, H., Sato, S., Kogure, T., Arimitsu, N., Tagaya, M., Tani, K.
- Organizer
  Sapporo International Cancer Symposium 2010 "Membranetraffic and Cancer"
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PUBLICLY-22020034
[Presentation] KIAA0725p/DDHD2, a mammalian Golgi-associated phospholipase A_1, regulates membrane trafficking from the Golgi apparatus to the plasma membrane.2010
- Author(s)
  Inoue, H., Sato, S., Kogure, T., Arimitsu, N., Tagaya, M., Tani, K.
- Organizer
  Sapporo International Cancer Symposium 2010 "Membranetraffic and Cancer"
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21770150
[Presentation] Sec16Bはミトコンドリアおよびペルオキシソームの形態形成に関与する2009
- Author(s)
  米川周佑、中島寿基、井上弘樹、多賀谷光男、谷佳津子
- Organizer
  日本生化学会第82回大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21770150
[Presentation] g-SNAPはエンドソームSNAREの解離を促進し，初期エンドソームからの小胞輸送に機能する
- Author(s)
  井上弘樹，松崎友香，田中理華，細井香里，浅野謙一，田中正人，奥崎大介，多賀谷光男
- Organizer
  第87回日本生化学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26440064

1. TAGAYA Mitsuo (30179569)

# of Collaborated Projects: 7 results

# of Collaborated Products: 17 results
2. KANAZAWA Hiroshi (50116448)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. NAKAMURA Norihiro (90324748)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
4. FUKUYAMA Keiichi (80032283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MITSUI Keiji (60379279)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 若菜裕一 (90635187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. HASHIMOTO Yoshitami (50616761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ARASAKI Kohei (70609990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MATSUSHITA Masafumi (50403100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 荻原哲 (30169221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 谷佳津子 (40266896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 金沢浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 26 results
13. 伊東史子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 馬場則男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 馬場美鈴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 宍戸佳津子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 村手源英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Inoue Hiroki 井上 弘樹

INOUE Hiroki 井上 弘樹

井上 弘樹 イノウエ ヒロキ

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A study of membrane trafficking-cytoskeleton networks that promote cancer cell growth and metastasisPrincipal Investigator

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A crosstalk between membrane trafficking and cytoskeletons in invadopodia in cancer cellsPrincipal Investigator

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Identification of membrane fusion machineries for cancer cell invasionPrincipal Investigator

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Molecular mechanisms of receptor trafficking by a phosphatidic acid-interacting Rab11 effector and their regulatorsPrincipal Investigator

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Regulation of receptor trafficking and cytoskeleton by Arf small G proteins and their effectorsPrincipal Investigator

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Na^+/H^+交換輸送蛋白質NhaAのpHセンサーおよびイオン交換輸送機構の解析Principal Investigator

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Na^+/H^+交換輸送蛋白質NhaAのpHセンサー機構の解明Principal Investigator

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Inoue Hiroki 井上弘樹

INOUE Hiroki 井上弘樹

井上弘樹イノウエヒロキ