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ichiro itonaga  糸永 一朗

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糸永 一朗  イトナガ イチロウ

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Researcher Number 10295181
Other IDs
Affiliation (Current) 2020: 大分大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2014 – 2019: 大分大学, 医学部, 講師
2005: 大分大学, 医学部, 講師
2004: 大分大学, 医学部, 助手
2001: 大分医大, 医学部, 助手
2000: 大分医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Keywords
Principal Investigator
破骨細胞 / 人工関節 / loosening / osteolysis / 摩耗紛 / 骨破壊 / 骨転移 / 肉腫 / 染色体不安定性 / c-myc … More / 染色体転座 / エピジェネティクス / cmyc / 骨肉腫 / 間葉系幹細胞 / 液性因子 / Ewing肉腫 / RNA helicase A / EWS-Fli1 / RNAヘリカーゼA Less
  • Research Projects

    (5 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (4 People)
  •  ユーイング肉腫特異的融合遺伝子によるRNAヘリカーゼAの機能抑制に関する研究Principal InvestigatorOngoing

    • Principal Investigator
      糸永 一朗
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Oita University
  •  Interaction between human osteosarcoma cells and mesenchymal stem cells via IL-8 signaling in tumor microenvironment.Principal Investigator

    • Principal Investigator
      Itonaga Ichiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Oita University
  •  Epigenetic abnormality induced by aberrant c-Myc expression leads to the chromosomal instability.Principal Investigator

    • Principal Investigator
      ichiro itonaga
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Oita University
  •  骨転位をきたした乳癌細胞による骨破壊および腫瘍増大機序の解明Principal Investigator

    • Principal Investigator
      糸永 一朗
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Oita University
  •  人工関節周囲に生じる骨溶解の病態解明Principal Investigator

    • Principal Investigator
      糸永 一朗
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      大分医科大学

All 2019 2018 2016 2015 2005 Other

All Journal Article Presentation

  • [Journal Article] Surrogacy of intermediate endpoints for overall survival in randomized controlled trials of first-line treatment for advanced soft tissue sarcoma in the pre- and post-pazopanib era: a meta-analytic evaluation.2019

    • Author(s)
      Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
    • Journal Title

      BMC Cancer

      Volume: 19 Pages: 56-56

    • DOI

      10.1186/s12885-019-5268-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
  • [Journal Article] A meta-analysis of randomized controlled trials that compare standard doxorubicin with other first-line chemotherapies for advanced/metastatic soft tissue sarcomas2019

    • Author(s)
      Tanaka K, Kawano M, Iwasaki T, Itonaga I, Tsumura H.
    • Journal Title

      PLoS One.

      Volume: 14 Pages: 1-18

    • DOI

      10.1371/journal.pone.0210671

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10866, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K16666
  • [Journal Article] Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment2018

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Cell Communication and Signaling

      Volume: 16(1) Pages: 1-11

    • DOI

      10.1186/s12964-018-0225-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
  • [Journal Article] MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing’s sarcoma cells2018

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Cancer Cell International

      Volume: 18 Pages: 1-11

    • DOI

      10.1186/s12935-018-0536-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-18K09110, KAKENHI-PROJECT-16K10866
  • [Journal Article] MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells2018

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Int J Oncol

      Volume: 51(6) Pages: 1842-1850

    • DOI

      10.3892/ijo.2017.4155

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10971, KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-16K10866
  • [Journal Article] Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing’s sarcoma cells.2016

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
    • Journal Title

      Int J Oncol

      Volume: Mar;48(3): Pages: 1135-1144

    • DOI

      10.3892/ijo.2016.3317

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
  • [Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Produces Antitumor Effects in Osteosarcoma.2016

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H.
    • Journal Title

      Oncology Letters.

      Volume: 11 Pages: 2169-2175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670668
  • [Journal Article] MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing’s sarcoma cells2016

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
    • Journal Title

      Int J Oncol

      Volume: Apr;48(4): Pages: 1531-1540

    • DOI

      10.3892/ijo.2016.3379

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200, KAKENHI-PROJECT-15K10451
  • [Journal Article] microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells.2015

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Ikeda S, Iwasaki T, Tsumura H
    • Journal Title

      Journal of Experimental & Clinical Cancer Research.

      Volume: 34 Pages: 76-76

    • DOI

      10.1186/s13046-015-0192-z

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] Tumor-suppressive microRNA-let-7a inhibits cell proliferation via targeting of E2F2 in osteosarcoma cells.2015

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, Tsumura H
    • Journal Title

      International Journal of Oncology

      Volume: 34 Pages: 1543-1550

    • DOI

      10.3892/or.2015.4161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] Tumor-suppressive microRNA-let-7a inhibits cell2015

    • Author(s)
      Iwasaki T, Tanaka K, Kawano M, Itonaga I, Tsumura H
    • Journal Title

      International Jnournal of Oncology.

      Volume: 46 Pages: 1543-1550

    • DOI

      10.3892/ijo.2015.2867

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592250, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] c-Myc Represses Tumor-Suppressive microRNAs, let-7a, miR-16 and miR-29b, and Induces Cyclin D2-Mediated Cell Proliferation in Ewing's Sarcoma Cell Line.2015

    • Author(s)
      Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H
    • Journal Title

      PLoS One

      Volume: 10

    • DOI

      10.1371/journal.pone.0138560

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10451, KAKENHI-PROJECT-26670668, KAKENHI-PROJECT-26861200
  • [Journal Article] Dendritic Cells Combined with Immunogenic Cell Death Induced by Doxorubicin Exhibits Antitumor Effects for Osteosarcoma2015

    • Author(s)
      M. Kawano, K. Tanaka, I. Itonaga, T. Iwasaki, M. Miyazaki, S. Ikeda, H. Tsumura
    • Journal Title

      Oncology Leteers

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670668
  • [Journal Article] Macrophages that have phagocytosed particles are capable of differentiating into functional osteoclasts2005

    • Author(s)
      Yosuke Fujikawa, Ichiro Itonaga, Osami Kudo, Takahisa Hirayama
    • Journal Title

      Modern Rheumatology 15・5

      Pages: 346-351

    • Data Source
      KAKENHI-PROJECT-16790849
  • [Journal Article] Infliximab acts directly on human osteoclast precursors and enhances osteoclast formation induced by receptor activator of nuclear factor kB ligand in vitro2005

    • Author(s)
      Chikahiro Takita, Yosuke Fujikawa, Ichiro Itonaga, et al.
    • Journal Title

      Modern Rheumatology 15・2

      Pages: 97-103

    • Data Source
      KAKENHI-PROJECT-16790849
  • [Journal Article] Infliximab acts directly on human osteoclast precursors and enhances osteoclast formation induced by RANKL in vitro

    • Author(s)
      Takita C., Fujikawa Y., Itonaga I.et al.
    • Journal Title

      Modern Rheumatology (掲載予定)

    • Data Source
      KAKENHI-PROJECT-16790849
  • [Presentation] microRNA-301a promotes cell proliferation via targeting of PTEN in Ewing’s sarcoma cells2015

    • Author(s)
      M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura.
    • Organizer
      Japan Muscular Skeletal Tumor Society Meeting
    • Place of Presentation
      かがわ国際会議場(香川県、高松市)
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-26670668
  • [Presentation] microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells.2015

    • Author(s)
      M Kawano, K Tanaka, I. Itonaga, T. Iwasaki, H. Tsumura
    • Organizer
      Annual research meeting of the Japanese orthopedic association
    • Place of Presentation
      富山国際会議場(富山県、富山市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-26670668
  • [Presentation] 当科におけるパゾパニブの臨床使用経験

    • Author(s)
      糸永一朗
    • Organizer
      日本整形外科学会骨・軟部腫瘍学術集会
    • Place of Presentation
      大阪国際会議場(大阪府、大阪市)
    • Year and Date
      2014-07-17 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-26670668
  • [Presentation] 関節症状なく足底にリウマトイド結節が生じた1例

    • Author(s)
      糸永一朗
    • Organizer
      日本リウマチ学会総会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都港区)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-26670668
  • 1.  TANAKA Kazuhiro (10274458)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 2.  池田 真一 (70444883)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  河野 正典 (30571773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 4.  岩崎 達也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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