Kikuchi Hidehiko 菊池秀彦

… Alternative Names

KIKUCHI Hidehiko 菊池秀彦

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Researcher Number	10301384
Other IDs	https://orcid.org/0000-0003-2608-6546
Affiliation (Current)	2024: 尚絅大学短期大学部, その他部局等, 教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 尚絅大学短期大学部, その他部局等, 教授 2013 – 2014: 宮崎大学, 医学部, 助教 2009 – 2011: 宮崎大学, 医学部, 助教 2003 – 2006: University of Miyazaki, Frontier Science Research Center, Research Associate, フロンティア科学実験総合センター, 助手 2003: 宮崎大学, 医学部・フロンティア科学実験総合センター, 助手 1998 – 2002: Miyazaki Medical College, Assistant Professor, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 08030:Family and consumer sciences, and culture and living-related / Eating habits / Genome biology / Molecular biology Except Principal Investigator Biological Sciences / Structural biochemistry / 基礎ゲノム科学 / Basic Section 08030:Family and consumer sciences, and culture and living-related / Molecular biology / Genome biology
Keywords	Principal Investigator 活性酸素 / フィトケミカル / 食品成分 / 腸管細胞 / 遺伝子発現 / スーパーオキシド / 白血球 / ヒストン / ヒストンアセチル化 / エピジェネティクス … More / GCN5 / DT40 / Nox1 / 大腸上皮細胞 / 定量性ＰCＲ / 定量性PCR / 大腸細胞 / エクオール / スルフォラファン / カルコン / 分化誘導 / 活性酸素産生系 / 腸内細菌 / エラグ酸 / 3',4'-ジヒドロキシフラボン / 白血球分化 / 腸管 / L-テアニン / ウロリチンA / Nox2 / 自然免疫 / マクロファージ / レスベラトロール / カルコノイド / 細胞毒性 / 細胞分化 / U937 / IRF-4 / Blimp-1 / epigenetics / B cell differentiation / gene expression / histone acetylation / 免疫グロブリン / PCAF / 遺伝子ターゲッティング / ヒストンアセチル化酵素 / 転写制御 / B細胞 / 遺伝子ノックアウト / B細胞分化 / ヒストンアセチルトランスフェラーゼ / ジーンノックアウト / 細胞周期 / CAF / P … More Except Principal Investigator ジーンノックアウト法 / クロマチン構造 / ヒストン修飾酵素 / ヒストン / DT40 / 転写制御 / アポトーシス / 細胞周期 / ヒストンシャペロン / DT40細胞 / 細胞増殖 / 免疫グロブリン / 2次元電気泳動 / 遺伝子発現 / Immunoglobulin / Gene targeting technique / DT40株 / クロマチン / カタボライトレプレッション / 枯草菌 / 細胞老化 / 糖尿病 / 食後高血糖 / Gene expression / Apoptosis / Histone chaperone / Cell cycle / Gene targeting / Histone modifying enzyme / gene expression / transcriptional control / acetylation / histone / 脱アセチル化酵素 / アセチル化 / Cell proliferation / DT40 cells / Histone-modifying enzyme / Histone / Chromatin / ヒストンデアセチラーゼ / 2D-PAGE / Transcription regulation / Chromatin structure / Histone variants / 2次元電気泳動法 / ヒストンバリアント / チロシンキナーゼ / GCN5 / PI3キナーゼ/Akt経路 / 活性酸素 / プロテインキナーゼ / スーパーオキシド産生系 / B細胞 / 遺伝子破壊法 / リンパ球特異的転写因子 / ヒストンアセチルトランスフェラーゼ / ジーンノックアスト法 / DNA障害 / チェックポイント / DNA複製 / ヌクレオソーム / クロマチンアセンブリーファクター / ヒストンアセチル化酵素 / ヒストン脱アセチル化酵素 / 発現制御 / ゲノム / 遺伝子 / クロマチン会合 / ジーントックアウト法 / コートタンパク質 / 熱抵抗性 / スポア / 遺伝子欠失変異株 / 発芽 / 胞子 / 特定遺伝子欠失変異株 Less

食後高血糖における新規細胞老化シグナルの増大およびその作用機序の総括的解明
- Principal Investigator
  
  實松史幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Shokei University
摂取した食品成分等が大腸上皮細胞の活性酸素産生系Nox1に及ぼす影響の総括的解析Principal Investigator
- Principal Investigator
  
  菊池秀彦
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Shokei Junior College
Studies on the molecular mechanisms of the effects of ingested phytochemicals on the reactive oxygen species-generating system of cells in the intestinal tractPrincipal Investigator
- Principal Investigator
  
  Kikuchi Hidehiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Shokei Junior College
Effects of phytochemicals in food on regulation of cell functions via histone modificationPrincipal Investigator
- Principal Investigator
  
  Kikuchi Hidehiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Shokei Junior College
Investigation of the physiological functions of histone modifying enzymes by gene targeting techniquesPrincipal Investigator
- Principal Investigator
  
  Kikuchi Hidehiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Shokei Junior College
  University of Miyazaki
ヒストン修飾酵素と転写因子の共同作業によるB細胞特異的なアポトーシス制御システム
- Principal Investigator
  
  中山建男
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  University of Miyazaki
Functional analyses of chromatin structure changing-related factors in higher eukaryotic cells by gene targeting techniques
- Principal Investigator
  
  NAKAYAMA Tatsuo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  University of Miyazaki
高等真核細胞のクロマチン構造動態とゲノム機能発現制御機構の網羅的解明
- Principal Investigator
  
  中山建男
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
Mechanisms for all-inclusive controls of cell cycle progression, and IgM H and L-chain gene expressions by GCN5 and HDAC2
- Principal Investigator
  
  NAKAYAMA Tatsuo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  University of Miyazaki
高等真核細胞のクロマチン構造動態とゲノム機能発現制御機構の解明
- Principal Investigator
  
  中山建男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  宮崎医科大学
高等真核細胞のクロマチン構造動態とゲノム機能発現制御機構の解明
- Principal Investigator
  
  中山建男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  宮崎医科大学
ジーンノックアウト法を用いた高等真核生物GCN5ファミリーの機能解析Principal Investigator
- Principal Investigator
  
  菊池秀彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  宮崎医科大学
Study on the regulatory mechanism for immunoglobulin expression through histone acetylation
- Principal Investigator
  
  TAKECHI Shinji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  宮崎医科大学
クロマチン構造改変DT40細胞の系統的作成によるゲノム機能解析
- Principal Investigator
  
  中山建男
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  宮崎医科大学
2次元電気泳動法による特定遺伝子欠失変異株の遺伝子発現パターンの網羅的解析
- Principal Investigator
  
  中山建男
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  宮崎医科大学
Joint study on histone modifying enzymes by gene disruption
- Principal Investigator
  
  NAKAYAMA Tatsuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Structural biochemistry
- Research Institution
  Miyazaki Medical College
2次元電気泳動法による特定遺伝子欠失変異株の遺伝子産物のマッピングと構造決定
- Principal Investigator
  
  NAKAYAMA Tatsuo
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  宮崎医科大学
Joint Study on Nature of Histone Variants by Gene Disruption
- Principal Investigator
  
  NAKAYAMA Tatsuo
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Miyazaki Medical College

[Book] Advances in Genetics Research vol.22010
- Author(s)
  Kikuchi H
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-19310127
[Book] Advances in Genetics Research Vol.22010
- Author(s)
  Hidehiko Kikuchi
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-22510203
[Book] Studies on epigenetic control of B cell functions using the DT40 cell line.(Advances in Genetics Research Vol.2)2010
- Author(s)
  Kikuchi, H., Barman, H.K., Nakayama, M., Takami, Y., Nakayama, T.
- Publisher
  Nova Science Publishers, Inc. NY
- Data Source
  KAKENHI-PROJECT-19310127
[Book] Reviews and Protocols in DT40 Research : Participation of histones, histone modifying enzymes and histone chaperones in vertebrate cell functions2006
- Author(s)
  Kikuchi, H., Barman, H.K., Nakayama, M., Takami, Y., Nakayama, T.
- Publisher
  Springer-Verlag
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] Production and evaluation of a unique type of bread using inulin as the only carbohydrate source for bread fermentation with the inulinase-producing yeast, Kluyveromyces marxianus.2024
- Author(s)
  Hidehiko Kikuchi, Sayaka Fujita, Kaori Harata, Mayu Betto, Yuko Moriguchi, Fumiyuki Sanematsu, Harishkumar Madhyastha, Takefumi Sagara.
- Journal Title
  
  Current Topics in Biotechnology
  
  Volume: 14 Pages: 13-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K02128
[Journal Article] Production of N-acetyllactosamine using transgalactosylation activity of Aspergillus oryzae in Czapek-Dox liquid medium2023
- Author(s)
  Hidehiko Kikuchi
- Journal Title
  
  Journal of Association of Food Science Education in Japan
  
  Volume: 14 Pages: 9-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K02173
[Journal Article] Production and evaluation of a unique type of bread using inulin as the only carbohydrate source for bread fermentation with the inulinase-producing yeast, Kluyveromyces marxianus2023
- Author(s)
  Hidehiko Kikuchi, Sayaka Fujita, Kaori Harata, Mayu Betto, Yuko Moriguchi, Fumiyuki Sanematsu, Harishkumar Madhyastha, Takefumi Sagara
- Journal Title
  
  Current Topics in Biotechnology
  
  Volume: 14 Pages: 13-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K02173
[Journal Article] Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-<i>trans</i> retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells2023
- Author(s)
  Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 10 Issue: 6 Pages: 233-240
- DOI
  10.2131/fts.10.233
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K02173
[Journal Article] Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells2022
- Author(s)
  Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 9 Issue: 5 Pages: 151-157
- DOI
  10.2131/fts.9.151
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K02173
[Journal Article] Potential role of green tea amino acid L-theanine in activation of innate immune response via enhancing expression of cytochrome b 558 responsible for the reactive oxygen species-generating ability of leukocytes2022
- Author(s)
  Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Futoshi Kuribayashi
- Journal Title
  
  Microbiology and Immunology
  
  Volume: - Issue: 6 Pages: 342-349
- DOI
  10.1111/1348-0421.12977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329, KAKENHI-PROJECT-19K02309, KAKENHI-PROJECT-22K02173
[Journal Article] Pheophorbide-a acts as a photodynamic DNA-damaging reagent that causes remarkable increase in 8-hydroxydeoxyguanosine in cellular DNA2022
- Author(s)
  Hidehiko Kikuchi
- Journal Title
  
  Journal of Association of Food Science Education in Japan
  
  Volume: 13 Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K02173
[Journal Article] 3’, 4’-Dihydroxyflavone enhances all-<i>trans</i> retinoic acid-induced superoxide-generating activity through up-regulating transcription of gp91-phox in human monoblastic U937 cells, as opposed to flavone and other hydroxyflavone derivatives2021
- Author(s)
  Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Harishkumar Madhyastha, Futoshi Kuribayashi
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 8 Issue: 2 Pages: 53-59
- DOI
  10.2131/fts.8.53
- NAID
  130008044474
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Possibility for nutritional improvement of the "authentic milk bread" by increasing the amount of milk added2021
- Author(s)
  Aya Shibata, Sayaka Ichihara, Miwa Kubota, Aimi Sakata, Ayaka Shibata, Yuko Moriguchi, Kaori Harata, Takefumi Sagara, Hidehiko Kikuchi
- Journal Title
  
  Journal of Association of Food Science Education in Japan
  
  Volume: 12 Pages: 25-30
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Transcriptional profiles of histone acetyltransferases in human monoblast U937 cells treated with all-trans retinoic acid or 1α,25-dihydroxyvitamin D32021
- Author(s)
  Hidehiko Kikuchi, Yumi Nakagawa, Yui Hirayama, Kaori Harata
- Journal Title
  
  Journal of Association of Food Science Education in Japan
  
  Volume: 12 Pages: 19-24
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells2021
- Author(s)
  Hidehiko Kikuchi, Kaori Harata, Harishkumar Madhyastha, Futoshi Kuribayashi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 25 Pages: 100891-100891
- DOI
  10.1016/j.bbrep.2020.100891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Sulforaphane shows growth inhibitory effects against Escherichia coli and Bacillus subtilis via reactive oxygen species production2020
- Author(s)
  Tsuruta Chigusa, Mimura Akari, Harata Kaori, Kikuchi Hidehiko
- Journal Title
  
  Journal of Association of Food Science Education in Japan
  
  Volume: 11 Pages: 9-12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Production and evaluation of the authentic milk bread using a lactose-utilizing yeast, Kluyveromyces marxianus2020
- Author(s)
  Aya Shibata, Kaori Harata, Yuko Moriguchi, Risako Kanegawa, Ayaka Nagahira, Misaki Shigematsu, Yuri Takamura, Haruno Watanabe, Takefumi Sagara, Harishkumar Madhyastha, Hidehiko Kikuchi
- Journal Title
  
  Current Topics in Biotechnology
  
  Volume: 11 Pages: 31-36
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Sulforaphane shows remarkable growth inhibition and cytotoxicity against several human leukemia cell lines2020
- Author(s)
  Akiyoshi Sumiko, Kikuchi Hidehiko, Minami Hisanori
- Journal Title
  
  Journal of Association of Food Science Education in Japan
  
  Volume: 11 Pages: 1-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils2020
- Author(s)
  Hidehiko Kikuchi, Kaori Harata, Chikage Kawai, Harishkumar Madhyastha, Akira Yamauchi, Futoshi Kuribayashi
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 7 Issue: 4 Pages: 201-206
- DOI
  10.2131/fts.7.201
- NAID
  130007847965
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells2019
- Author(s)
  Akiyoshi Sumiko, Kikuchi Hidehiko, Kuribayashi Futoshi, Madhyastha Harishkumar, Minami Hisanori
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 6 Issue: 8 Pages: 319-325
- DOI
  10.2131/fts.6.319
- NAID
  130007760707
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Chalcone skeleton promotes transcription of gp91-phox gene but inhibits expression of gp91-phox protein, and hydroxyl groups in hydroxychalcones participate in the stable expression of gp91-phox protein.2019
- Author(s)
  Kikuchi H, Mimuro H, Madhyastha H, Kuribayashi F.
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 63 Issue: 10 Pages: 438-443
- DOI
  10.1111/1348-0421.12732
- NAID
  40022036987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07804, KAKENHI-PROJECT-19K02329
[Journal Article] Functions of B cell development-related transcription factors systematically revealed in immature B cells by gene targeting techniques using chicken DT40 cells2019
- Author(s)
  Kikuchi Hidehiko, Kuribayashi Futoshi, Nakayama Masami, Nakayama Tatso
- Journal Title
  
  Current Topics in Biochemical Research
  
  Volume: 20 Pages: 43-52
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02329
[Journal Article] Enzymatic preparation of O-β-D-galactopyranosyl-(1,6)-2-amino-2-deoxy-D-gluconic acid by transgalactosylation catalyzed by Aspergillus oryzae β-D-galactosidase2018
- Author(s)
  Hidehiko Kikuchi
- Journal Title
  
  Journal of Association of Food Science Education in Japan
  
  Volume: 9 Pages: 9-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00895
[Journal Article] Gene targeting techniques reveal that histone acetyltransferase GCN5 has various inherent physiological functions in chicken DT40 cells2018
- Author(s)
  Hidehiko Kikuchi, Futoshi Kuribayashi, Masami Nakayama, Tatsuo Nakayama
- Journal Title
  
  Current Topics in Biochemical Research
  
  Volume: 19 Pages: 13-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00895
[Journal Article] Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells2018
- Author(s)
  Kikuchi Hidehiko、Mimuro Hitomi、Kuribayashi Futoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 1 Pages: 1195-1200
- DOI
  10.1016/j.bbrc.2017.11.161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00895, KAKENHI-PROJECT-17K19551, KAKENHI-PROJECT-15K09671
[Journal Article] Positions and numbers of hydroxyl groups in hydroxychalcone derivatives are involved in cytotoxicity against human monoblastic U937 cells2018
- Author(s)
  Hidehiko Kikuchi, Futoshi Kuribayashi, Harishkumar Madhyastha
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 5 Issue: 4 Pages: 149-152
- DOI
  10.2131/fts.5.149
- NAID
  130007494040
- ISSN
  2189-115X
- Year and Date
  2018-09-29
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00895
[Journal Article] GCN5-deficiency remarkably enhances the sensitivity of B cells in response to 4-nitroquinoline 1-oxide2016
- Author(s)
  Hidehiko Kikuchi, Futoshi Kuribayashi, Hitomi Mimuro and Shinobu Imajoh-Ohmi
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 3 Issue: 3 Pages: 137-142
- DOI
  10.2131/fts.3.137
- NAID
  130005152906
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00895
[Journal Article] Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells.2015
- Author(s)
  Kikuchi H, Nakayama M, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Nakayama T.
- Journal Title
  
  Biochem Biophys Res Commun. Nov 20;(3):509-13.
  
  Volume: 467 Issue: 3 Pages: 509-513
- DOI
  10.1016/j.bbrc.2015.10.011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09671, KAKENHI-PROJECT-15K15685, KAKENHI-PROJECT-25430170
[Journal Article] Paired box gene 5 isoforms A and B have different functions in transcriptional regulation of B cell development-related genes in immature B cells.2015
- Author(s)
  Kikuchi H, Nakayama M, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T:
- Journal Title
  
  Microbiol. Immunol.
  
  Volume: 59 Issue: 7 Pages: 426-431
- DOI
  10.1111/1348-0421.12272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05019, KAKENHI-PROJECT-25430170
[Journal Article] The histone acetyltransferase p300/CBP-associated factor acts as an effective suppressor of secretory immunoglobulin synthesis in immature B cells2015
- Author(s)
  Hidehiko Kikuchi, Masami Nakayama, Chikage Kawai, Futoshi Kuribayashi, Hitomi Mimuro, Shinobu Imajoh-Ohmi, Nishitoh H, Yasunari Takami, and Tatsuo Nakayama
- Journal Title
  
  Microbiol. Immunol
  
  Volume: 59 Issue: 4 Pages: 243-247
- DOI
  10.1111/1348-0421.12237
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591563, KAKENHI-PROJECT-25430170, KAKENHI-PROJECT-15H05019
[Journal Article] Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression.2015
- Author(s)
  Kikuchi H, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nakayama M, Takami Y, Nishitoh H, Nakayama T:
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 463 Issue: 4 Pages: 870-875
- DOI
  10.1016/j.bbrc.2015.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05019, KAKENHI-PROJECT-25430170
[Journal Article] Protein kinase Cθ gene expression is oppositely regulated by GCN5 and EBF1 in immature B cells.2014
- Author(s)
  Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T
- Journal Title
  
  FEBS Lett
  
  Volume: 588 Issue: 9 Pages: 1739-1742
- DOI
  10.1016/j.febslet.2014.03.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390418, KAKENHI-PROJECT-25430170, KAKENHI-PROJECT-25670790, KAKENHI-PROJECT-26440007
[Journal Article] Down-regulation of Fas-mediated apoptosis by plasma transglutaminase factor XIII that catalyzes fetal-specific cross-link of the Fas molecule.2014
- Author(s)
  Kikuchi H, Kuribayashi F, Imajoh-Ohmi S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 443 Issue: 1 Pages: 13-17
- DOI
  10.1016/j.bbrc.2013.10.163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591563, KAKENHI-PROJECT-25430170
[Journal Article] GCN5 is involved in regulation of immunoglobulin heavy chain gene expression in immature B cells.2014
- Author(s)
  Kikuchi H., Nakayama M., Kuribayashi F., Imajoh-Ohmi S., Nishitoh H., Takami Y., Nakayama T.
- Journal Title
  
  Gene
  
  Volume: 544 Issue: 1 Pages: 19-24
- DOI
  10.1016/j.gene.2014.04.030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390418, KAKENHI-PROJECT-25430170, KAKENHI-PROJECT-25670790, KAKENHI-PROJECT-26440007
[Journal Article] GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells.2014
- Author(s)
  Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T.
- Journal Title
  
  J Leukoc Biol
  
  Volume: 95 Issue: 3 Pages: 399-404
- DOI
  10.1189/jlb.0413232
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390418, KAKENHI-PROJECT-24591563, KAKENHI-PROJECT-25430170, KAKENHI-PROJECT-25670790, KAKENHI-PROJECT-26440007
[Journal Article] GCN5 regulates the superoxide-generating system in leukocytes via controlling gp91-phox gene expression2011
- Author(s)
  Hidehiko Kikuchi
- Journal Title
  
  The Journal of Immunology
  
  Volume: VOL.186 Pages: 3015-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510203
[Journal Article] GCN5 regulates the superoxide-generating system in Leukocytes via controlling gp91-phox gene expression.2011
- Author(s)
  Kikuchi, H., Kuribayashi, F., Kiwaki, N., Takami, Y., Nakayama, T.
- Journal Title
  
  J. Immunology 186
  
  Pages: 3015-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] GCN5 regulates the activation of PI3K/Akt survival pathway in B cells exposed to oxidative stress via controlling gene expressions of Syk and Btk.2011
- Author(s)
  Kikuchi, H., Kuribayashi, F., Takami, Y., Imajoh-Ohmi, S., Nakayama, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 405
  
  Pages: 657-661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs Results in Immunology2011
- Author(s)
  Hidehiko Kikuchi, Masami Nakayama, Yasunari Takami, Futoshi Kuribayashi, Tatsuo Nakayama
- Journal Title
  
  Results in Immunology
  
  Volume: 1 Issue: 1 Pages: 88-94
- DOI
  10.1016/j.rinim.2011.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591365, KAKENHI-PROJECT-22510203
[Journal Article] GCN5 regulates the activation of PI3K/Akt survival pathway in B cells exposed to oxidative stress via controlling gene expressions of Syk and Btk2011
- Author(s)
  Hidehiko Kikuchi, Futoshi Kuribayashi, Yasunari Takami, Shinobu Imajoh-Ohmi, and Tatsuo Nakayama
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 405 Issue: 4 Pages: 657-661
- DOI
  10.1016/j.bbrc.2011.01.088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591365, KAKENHI-PROJECT-22510203
[Journal Article] GCN5 regulates the superoxide generating system in leukocytes via controlling gp91-phox gene expression2011
- Author(s)
  Hidehiko Kikuchi, Futoshi Kuribayashi, Naomi Kiwaki, Yasunari Takami, and Tatsuo Nakayama
- Journal Title
  
  J. Immunol
  
  Volume: 186 Issue: 5 Pages: 3015-3022
- DOI
  10.4049/jimmunol.1000364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591365, KAKENHI-PROJECT-22510203
[Journal Article] Curcumin dramatically enhances retinoic acid-induced superoxide generating activity via accumulation of p47-phox and p67-phox proteins in U937 cells.2010
- Author(s)
  Kikuchi, H., Kuribayashi, F., Kiwaki, N., Nakayama, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 395
  
  Pages: 61-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Curcumin dramatically enhances retinoic acid-induced superoxide generating activity via accumulation of p47-phox and p67-phox in U937 cells2010
- Author(s)
  Hidehiko Kikuchi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: VOL.395 Pages: 61-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510203
[Journal Article] Lacking of Aiolos accelerates pre-mature B cell apoptosis mediated by BCR signaling through elevation in cytochrome c release2009
- Author(s)
  Kikuchi H.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1793 Pages: 1304-1314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] E2A participates in a fine control of pre-mature B cell apoptosis mediated by B cell receptor signaling via transcription regulations of survivin, IAP2 and caspase-8 genes.2009
- Author(s)
  Toyonaga, K., Kikuchi, H., Yamashita, K., Nakayama, M., Chijiiwa, K., Nakayama, T.
- Journal Title
  
  FEBS J. 276/5
  
  Pages: 1418-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Lacking of Aiolos accelerates pre-mature B cell apoptosis mediated by BCR signaling through elevation in cytochrome c release.2009
- Author(s)
  Kikuchi, H., Yamashita, K., Nakayama, M., Toyonaga, K., Tsuneyoshi, I., Takasaki, M., Nakayama, T.
- Journal Title
  
  BBA-Molecular Cell Research 1793
  
  Pages: 1304-1314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] E2A participates in a fine control of pre-mature B cell apoptosis mediated by B cell receptorsignaling via transcription regulations of survivin, IAP2 and caspase-8 genes.2009
- Author(s)
  *Toyonaga, K., *Kikuchi, H., Yamashita, K., Nakayama, M., Chijiiwa, K., Nakayama, T.
- Journal Title
  
  FEBS J. 276/5
  
  Pages: 1418-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Studies on epigenetic control of B cell functions using the DT40 cell line.2009
- Author(s)
  Kikuchi, H., Barman, H. K., Nakayama, M., Takami, Y., Nakayama, T.
- Journal Title
  
  Immunogenetics Research Progress, Nova Science Publishers, Inc. NY (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Studies on epigenetic control of B cell functions using the DT40 cell line2008
- Author(s)
  Kikuchi, H., Barman, H. K., Nakayama, M., Takami, Y. and Nakayama, T.
- Journal Title
  
  Immunogenetics Research Progress, Nova Science Publishers, Inc. NY (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] GCN5 and BCR signalling collaborate to induce pre-mature B cell apoptosis through depletion of ICAD and IAP2 and activation of caspase activities.2008
- Author(s)
  Kikuchi, H., Nakayama, T.
- Journal Title
  
  Gene 419
  
  Pages: 48-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Collaborative roles of rH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair2007
- Author(s)
  Sonoda, E., Zhao, G.-Y., Kohzaki, M., Dhar, P. K., Kikuchi, K., Redon, C., Pilch, D. R., Bonner, W. W., Nakano, A., Watanabe, M., Nakayama, T., Takeda, S. and Takami, Y.
- Journal Title
  
  DNA Repair 6
  
  Pages: 280-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Collaborative roles of rH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair.2007
- Author(s)
  Sonoda, E., Zhao, G-Y, Kohzaki, M., Dhar, P.K., Kikuchi, K., Redon, C., Pilch, D.R., Bonner, W.M., Nakano, A., Watanabe, M., Nakayama, T., Takeda, S., Takami, Y.
- Journal Title
  
  DNA Repair 6
  
  Pages: 280-292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] HDAC2 controls lgM H and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions2007
- Author(s)
  Nakayama, M., Suzuki, H., Yamamoto-Nagamatsu, N., Barman, H.K., Kikuchi, H., Takami, Y., Toyonaga, K., Yamashita, K., Nakayama, T.
- Journal Title
  
  Genes Cells 12
  
  Pages: 359-373
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] HDAC2 controls IgM H and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions2007
- Author(s)
  Nakayama, M., Suzuki, H., Yamamoto-Nagamatsu, N., Barman, H.K., Kikuchi, H., Takami, Y., Toyonaga, K, Yamashita, K., Nakayama, T.
- Journal Title
  
  Genes Cells 12
  
  Pages: 359-373
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] HDAC2 controls IgM H and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions.2007
- Author(s)
  Nakayama, M., Suzuki, H., Yamamoto-Nagamatsu, N., Barman, H.K., Kikuchi, H., Takami, Y., Toyonaga, K., Yamashita, K., Nakayama, T.
- Journal Title
  
  Genes Cells 12
  
  Pages: 359-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] HDAC2 controls IgM H and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions.2007
- Author(s)
  Nakayama, M., Suzuki, H., Yamamoto-Nagamatsu, N., Barman, H.K., Kikuchi, H., Takami, Y., Toyonaga, K., Yamashita, K., Nakayama, T.
- Journal Title
  
  Genes Cells 12
  
  Pages: 359-373
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] Collaborative roles of rH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair2007
- Author(s)
  Sonoda, E., Zhao, G.-Y., Kohzaki, M., Dhar, P.K., Kikuchi, K., Redon, C., Pilch, D.R., Bonner, W.M., Nakano, A., Watanabe, M., Nakayama, T., Takeda, S., Takami, Y.
- Journal Title
  
  DNA Repair 6
  
  Pages: 280-292
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] Collaborative roles of rH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair.2007
- Author(s)
  Sonoda, E., Zhao, G.-Y., Kohzaki, M., Dhar, P.K., Kikuchi, K., Redon, C., Pilch, D.R., Bonner, W.W., Nakano, A., Watanabe, M., Nakayama, T., Takeda, S., Takami, Y.
- Journal Title
  
  DNA Repair 6
  
  Pages: 280-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] HDAC2 controls IgM H and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions2007
- Author(s)
  Nakayama, M., Suzuki, H., Yamamoto-Nagamatsu, N., Barman, H. K., Kikuchi, H., Takami, Y., Toyonaga, K., Yamashita, K. and Nakayama, T.
- Journal Title
  
  Genes Cells 12
  
  Pages: 359-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310127
[Journal Article] Reviews and Protocols in DT40 Research : Participation of histones, histone modifying enzymes and histone chaperones in vertebrate cell functions.2006
- Author(s)
  Kikuchi, H., Barman, H.K., Nakayama, M., Takami, Y, Nakayama, T.
- Journal Title
  
  Springer-Verlag
  
  Pages: 225-243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] Different roles of N-terminal and C-terminal halves of HIRA in transcription regulation of cell cycle-related genes that contribute to control of vertebrate cell growth2005
- Author(s)
  Ahmad, A., Kikuchi, H., Takami, Y., Nakayama, T.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 32090-32100
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] GCN5 : a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.2005
- Author(s)
  Kikuchi, H., Takami, Y., Nakayama, T
- Journal Title
  
  Gene 347
  
  Pages: 83-97
- Data Source
  KAKENHI-PROJECT-16011249
[Journal Article] GCN5:a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.2005
- Author(s)
  Kikuchi, H., Takami, Y., Nakayama, T
- Journal Title
  
  Gene 347
  
  Pages: 83-97
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] GCN5 : a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.2005
- Author(s)
  Kikuchi, H., Takami, Y., Nakayama, T.
- Journal Title
  
  Gene 347
  
  Pages: 83-97
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] GCN5 : a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes2005
- Author(s)
  Kikuchi, H., Takami, Y., Nakayama, T.
- Journal Title
  
  Gene 347
  
  Pages: 83-97
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] Different roles of N-terminal and C-terminal halves of HIRA in transcription regulation of cell cycle-related genes that contribute to control of vertebrate cell growth.2005
- Author(s)
  Ahmad, A., Kikuchi, H., Takami, Y., Nakayama, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 32090-32100
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.2005
- Author(s)
  Kikuchi, H., Takami, Y., Nakayama, T.GCN5
- Journal Title
  
  Gene 347
  
  Pages: 83-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Journal Article] Different roles of N-terminal and C-terminal halves of HIRA in transcription regulation of cell cycle-related genes that contribute to control of vertebrate cell growth.2005
- Author(s)
  Ahmad, A., Kikuchi, H., Takami, Y., Nakayama, T.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 32090-32100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310134
[Patent] イヌリンを発酵させて製造されたパン、パン生地およびパンの製造法2023
- Inventor(s)
  菊池秀彦、相良剛史、實松史幸、原田香、藤田紗香
- Industrial Property Rights Holder
  菊池秀彦、相良剛史、實松史幸、原田香、藤田紗香
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-171728
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K02173
[Patent] イヌリンを発酵させて製造されたパン、パン生地およびパンの製造法2023
- Inventor(s)
  菊池秀彦, 相良剛史, 實松史幸, 原田香, 藤田紗香
- Industrial Property Rights Holder
  菊池秀彦, 相良剛史, 實松史幸, 原田香, 藤田紗香
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K02128
[Patent] パン、パン生地およびパンの製造方法2020
- Inventor(s)
  菊池秀彦、相良剛史、原田香、柴田文
- Industrial Property Rights Holder
  菊池秀彦、相良剛史、原田香、柴田文
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-099640
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K02329
[Patent] レチノイン酸効果増強剤およびこれを用いたリンパ腫治療剤キット、並びに、活性酸素産生促進剤およびこれを用いた免疫賦活剤2010
- Inventor(s)
  菊池秀彦、木脇直美、中山建男
- Industrial Property Rights Holder
  宮崎大学
- Industrial Property Number
  2010-059734
- Filing Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] 乳糖資化性酵母を用いた真正牛乳パンの製造と評価2023
- Author(s)
  原田香、森口裕子、相良剛史、菊池秀彦
- Organizer
  第72回日本食品保蔵科学会大会
- Data Source
  KAKENHI-PROJECT-22K02173
[Presentation] 白血球の活性酸素産生能に関与するシトクロムb558の発現増強を介した自然免疫応答の活性化における緑茶アミノ酸L-テアニンの潜在的役割2023
- Author(s)
  菊池秀彦、原田香、三室仁美、栗林太
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K02173
[Presentation] 食後高血糖における細胞老化分子の解析2022
- Author(s)
  實松史幸、菊池秀彦
- Organizer
  第95回日本生化学大会
- Data Source
  KAKENHI-PROJECT-22K02128
[Presentation] ウロリチンＡはgp91-phox遺伝子発現を増強することにより、U937細胞のレチノイン酸誘導性活性酸素産生能を亢進する2022
- Author(s)
  菊池秀彦、原田香、栗林太
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K02173
[Presentation] ヒドロキシカルコンの水酸基の数と位置がヒト白血病細胞U937に対する細胞毒性を決定する。2019
- Author(s)
  菊池秀彦、栗林太
- Organizer
  第42回日本分子生物学会年回
- Data Source
  KAKENHI-PROJECT-19K02329
[Presentation] レスベラトロールはgp91-phox遺伝子の発現増強を介してU937細胞のレチノイン酸誘導性スーパーオキシド産生能を強力に惹起する2018
- Author(s)
  菊池秀彦、三室仁美、栗林太
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K00895
[Presentation] Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells2017
- Author(s)
  Kikuchi Hidehiko、Mimuro Hitomi、Kuribayashi Futoshi
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K00895
[Presentation] Gene expression of immunoglobulin heavy chain is regulated by GCN5 and PCAF in immature B cells2016
- Author(s)
  Hidehiko Kikuchi, Futoshi Kuribayashi, Hitomi Mimuro and Shinobu Imajoh-Ohmi
- Organizer
  日本エピジェネティクス研究会第１０回年会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K00895
[Presentation] プロテインキナーゼCθの遺伝子発現はGCN5とEBF1によって正負に制御されている2015
- Author(s)
  菊池秀彦、中山雅美、栗林太、三室仁美、大海忍、西頭英起、高見恭成、中山建男
- Organizer
  日本エピジェネティクス研究会
- Place of Presentation
  東京一ツ橋学術総合センター
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-25430170
[Presentation] GCN5 is involved in regulation of immunoglobulin heavy chain gene expression in immature B cells2013
- Author(s)
  菊池秀彦、中山雅美、栗林太、大海忍、西頭英起、高見恭成、中山建男
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25430170
[Presentation] GCN5はDNAポリメラーゼηの発現制御を介して細胞を紫外線から保護する2013
- Author(s)
  菊池秀彦、栗林太、大海忍、西頭英起、高見恭成、中山建男
- Organizer
  第7回日本エピジェネティクス研究会年会
- Place of Presentation
  奈良県新公会堂
- Data Source
  KAKENHI-PROJECT-25430170
[Presentation] GCN5 regulates the superoxide-generating system in leukocytes via controlling gp91-phox gene expression2011
- Author(s)
  菊池秀彦、栗林太、高見恭成、中山建男
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22510203
[Presentation] GCN5によるB細胞酸化ストレス耐性機構の解析2011
- Author(s)
  菊池秀彦、栗林太、高見恭成、大海忍、中山建男
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22510203
[Presentation] クルクミンによる白血球スーパーオキシド産生系誘導増強効果2010
- Author(s)
  菊池秀彦
- Organizer
  第32回日本分子生物学会、第83回日本生化学会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22510203
[Presentation] クルクミンによる白血球スーパーオキシド産生系誘導増強効果2010
- Author(s)
  菊池秀彦、中山建男
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会、合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] GCN5による白血球スーパーオキシド産生系制御機構の解析2009
- Author(s)
  木脇直美、菊池秀彦、栗林太、中山建男
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] 転写因子E2AによるBリンパ球アポトーシス制御2009
- Author(s)
  菊池秀彦、豊永健二、山下幸貴、中山雅美、中山建男
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] 転写因子AiolosによるBリンパ球アポトーシス制御機構の解析2009
- Author(s)
  菊池秀彦、山下幸貴、中山雅美、豊永健二、中山建男
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] 転写因子E2AによるBリンパ球アポトーシス制御機構の解析2009
- Author(s)
  菊池秀彦、豊永健二、山下幸貴、中山雅美、中山建男
- Organizer
  日本分子生物学会第9回シンポジウム
- Place of Presentation
  宮崎
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] ヒストンアセチルトランスフェラーゼGCN5によるBCRシグナリング制御.2008
- Author(s)
  菊池秀彦, 中山建男
- Organizer
  第31回日本分子生物学会年会、第81回口本生化学会大会、合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] ヒストンアセチルトランスフェラーゼGCN5によるBCRシグナリング制御2008
- Author(s)
  菊池秀彦、中山建男
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] DT40細胞を用いた遺伝子ノックアウト法によるGCN5の機能解析2007
- Author(s)
  菊池秀彦、高見恭成、中山建男
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会、合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] DT40細胞を用いた遺伝子ノックアウト法によるGCN5の機能解析2007
- Author(s)
  菊池秀彦、高見恭成、中山建男
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  宮崎
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-19310127
[Presentation] Down-regulation of Fas-mediated apoptosis by plasma transglutaminase factor XIII that catalyzes fetal-specific cross-link of the Fas molecule
- Author(s)
  Hidehiko Kikuchi, Futoshi Kuribayashi, Hitomi Mimuro, Hideki Nishitoh, Shinobu Imajoh-Ohmi
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25430170
[Presentation] GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells
- Author(s)
  Hidehiko Kikuchi, Masami Nakayama, Futoshi Kuribayashi, Shinobu Imajoh-Ohmi, Hideki Nishitoh, Yasunari Takami, Tatsuo Nakayama
- Organizer
  第８回日本エピジェネティックス研究会年会
- Place of Presentation
  伊藤国際学術研究センター（東京大学構内）
- Year and Date
  2014-05-25 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-25430170

1. NAKAYAMA Tatsuo (60031712)

# of Collaborated Projects: 12 results

# of Collaborated Products: 40 results
2. TAKAMI Yasunari (80236356)

# of Collaborated Projects: 9 results

# of Collaborated Products: 26 results
3. TAKECHI Shinji (10222100)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. TAKEDA Shunichi (60188191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NISHITOH Hideki (00332627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. 實松史幸 (80381094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. Kuribayashi Futoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. BUERSTEDDE J

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. JEAN-MARIE Buerstedde

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. BUEROTEDLE U

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kikuchi Hidehiko 菊池 秀彦

KIKUCHI Hidehiko 菊池 秀彦

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摂取した食品成分等が大腸上皮細胞の活性酸素産生系Nox1に及ぼす影響の総括的解析Principal Investigator

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Studies on the molecular mechanisms of the effects of ingested phytochemicals on the reactive oxygen species-generating system of cells in the intestinal tractPrincipal Investigator

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Effects of phytochemicals in food on regulation of cell functions via histone modificationPrincipal Investigator

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Investigation of the physiological functions of histone modifying enzymes by gene targeting techniquesPrincipal Investigator

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ジーンノックアウト法を用いた高等真核生物GCN5ファミリーの機能解析Principal Investigator

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Kikuchi Hidehiko 菊池秀彦

KIKUCHI Hidehiko 菊池秀彦

[Journal Article] Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells2022