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KAWAGUCHI MASAKAZU  川口 雅一

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KAWAGUCHI Masakazu  川口 雅一

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Researcher Number 10302291
Other IDs
Affiliation (based on the past Project Information) *help 2015 – 2018: 山形大学, 医学部, 准教授
2012 – 2014: 山形大学, 医学部, 講師
2007 – 2010: Yamagata University, 医学部, 講師
2005 – 2006: 山形大学, 医学部, 助手
2000 – 2003: 山形大学, 医学部, 助手
2001: 山形大, 医学部, 助手
Review Section/Research Field
Principal Investigator
Dermatology / Dermatology / Basic Section 53050:Dermatology-related
Except Principal Investigator
Dermatology
Keywords
Principal Investigator
シグナル伝達 / メラニン / DGK / PMEL17 / メラノサイト / TACE / 創傷治癒 / MITF / 紫外線 / ADAM … More / 色素細胞 / メラノソーム / トランスジェニックマウス / diacylglycerol kinase / 表皮細胞 / S6 kinase / メラニン生合成 / BACE2 / メラニン合成 / pmel17 / melanosome / ADAM protease / 遺伝子改変マウス / TNF-α / 皮膚 / ケモカイン / ケラチノサイト / 増殖因子 / 肥満細胞 / TACE阻害剤 / 尋常性乾癖 / protein kinase C / real-time PCR / 尋常性乾癬 / 毛包 / 角化 / protein kinase C (PKC) / diacylglycerol kinase (DGK) … More
Except Principal Investigator
genodermatosis / mast cells / Becker's melanosis / segmental type / neurofibromatosis / mosaic / 結合組織型 / 粘膜型 / キマーゼ / トリプターゼ / 神経線維腫症 / 神経線維腫1型 / 扁平母斑 / ベーカー母斑 / chymase / tryptase / 肥満細胞 / モザイク / 神経線維腫症5型 / 神経線維腫症1型 Less
  • Research Projects

    (9 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (2 People)
  •  メラニン合成に関わる新規シグナル伝達機構Principal Investigator

    • Principal Investigator
      川口 雅一
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Yamagata University
  •  New targets for melanogenesisPrincipal Investigator

    • Principal Investigator
      Kawaguchi Masakazu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University
  •  The novel mechanisms for the regulation of melanogenesisPrincipal Investigator

    • Principal Investigator
      KAWAGUCHI MASAKAZU
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University
  •  皮膚におけるTNF-α変換酵素の機能解析Principal Investigator

    • Principal Investigator
      川口 雅一
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University
  •  The role of TNF-α converting enzyme in skinPrincipal Investigator

    • Principal Investigator
      KAWAGUCHI Masakazu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University
  •  組織特異的遺伝子改変マウスを用いた皮膚におけるTNF-α変換酵素の機能解析Principal Investigator

    • Principal Investigator
      川口 雅一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University
  •  脂質性2次メッセンジャー代謝酵素の皮膚における機能解析Principal Investigator

    • Principal Investigator
      川口 雅一
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University
  •  ジアシングリセロールキナーゼの皮膚における局在及び機能の解析Principal Investigator

    • Principal Investigator
      川口 雅一
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University
  •  Study on pathogenesis and heredity of mosaic genodermatoses

    • Principal Investigator
      MITSUHASHI Yoshihiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Yamagata University

All 2015 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] ADAM protease inhibitors reduce melanogenesis by regulating PMEL17 processing in human melanocytes2015

    • Author(s)
      Kawaguchi M, Hozumi Y, Suzuki T
    • Journal Title

      Journal of Dermatological Science

      Volume: 78 Issue: 2 Pages: 133-142

    • DOI

      10.1016/j.jdermsci.2015.02.020

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591641
  • [Presentation] The role of ADAM proteases on the processing of pmel172014

    • Author(s)
      Masakazu Kawaguchi, Yutaka Hozumi, Tamio Suzuki
    • Organizer
      第39回日本研究皮膚科学会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪市)
    • Year and Date
      2014-12-13
    • Data Source
      KAKENHI-PROJECT-24591641
  • [Presentation] ADAM protease inhibitor regulates chemokine expression in human keratinocytes, and modulates melanogenesis in human melanocytes2013

    • Author(s)
      Masakazu Kawaguchi, Yutaka Hozumi, Tamio Suzuki
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      Edinburgh International Conference Centre (Edinburgh, Scotland)
    • Data Source
      KAKENHI-PROJECT-24591641
  • [Presentation] 色素沈着のメカニズム

    • Author(s)
      川口雅一
    • Organizer
      第112回日本皮膚科学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591641
  • [Presentation] ADAM protease inhibitor modulates melanogenesis in human melanocytes

    • Author(s)
      Masakazu Kawaguchi, Yutaka Hozumi, Tamio Suzuki
    • Organizer
      12th international pigment cell conference
    • Place of Presentation
      Shangri-La Hotel (Singapore)
    • Year and Date
      2014-09-04 – 2014-09-07
    • Data Source
      KAKENHI-PROJECT-24591641
  • [Presentation] Diacylglycerol kinaseはメラノサイトのtyrosinase発現と機能を調節する

    • Author(s)
      川口雅一、Julio C. Valencia、Takeshi Namiki、鈴木民夫、Vincent J. Hearing
    • Organizer
      第24回日本色素細胞学会
    • Place of Presentation
      長浜バイオ大学(長浜市)
    • Data Source
      KAKENHI-PROJECT-24591641
  • [Presentation] ADAMプロテアーゼ阻害剤はヒトメラノサイトのmelanogenesisを調節する

    • Author(s)
      川口雅一、穂積 豊、鈴木民夫
    • Organizer
      第25回日本色素細胞学会学術大会
    • Place of Presentation
      大阪大学吹田キャンパス 銀杏会館(大阪市)
    • Data Source
      KAKENHI-PROJECT-24591641
  • [Presentation] Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes

    • Author(s)
      Masakazu Kawaguchi, Julio C. Valencia, Takeshi Namiki, Tamio Suzuki, Vincent J. Hearing
    • Organizer
      第37回日本研究皮膚科学会
    • Place of Presentation
      パシフィックホテル沖縄(那覇市)
    • Data Source
      KAKENHI-PROJECT-24591641
  • 1.  MITSUHASHI Yoshihiko (30157557)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  KATAGIRI Yoshiyuki (80292431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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