HANAGATA Nobutaka 花方信孝

… Alternative Names

花方信孝ハナガタノブタカ

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Researcher Number	10302796
Other IDs
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Affiliation (Current)	2025: 国立研究開発法人物質・材料研究機構, その他部局等, 理事 2025: 国立研究開発法人物質・材料研究機構, 技術開発・共用部門, マテリアル先端リサーチインフラセンターハブ代表
Affiliation (based on the past Project Information) *help	2016 – 2017: 国立研究開発法人物質・材料研究機構, 技術開発・共用部門, 副部門長 2015: 国立研究開発法人物質・材料研究機構, ナノテクノロジー融合ステーション, ステーション長 2014: 独立行政法人物質・材料研究機構, ナノテクノロジー融合ステーション, ステーション長 2011 – 2012: 独立行政法人物質・材料研究機構, その他部局等, 研究員 2011 – 2012: 独立行政法人物質・材料研究機構, ナノテクノロジー融合ステーション, ステーション長 2010: 独立行政法人物質・材料研究機構, ナノテクノロジー融合センター, 副センター長 2003 – 2004: 東京工科大学, バイオニクス学部, 教授
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Biofunction/Bioprocess / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Inorganic materials/Physical properties
Keywords	Principal Investigator 花粉症 / CpG / ワクチンアジュバント / マイクロニードル / 診断 / ミセル / バイオイメージング / 量子ドット / 免疫刺激 / デリバリー … More / ナノメディシン / DNA医薬 / DNA microarray / differential display / mangrove / salt tolerance / ディファレンシャル・ディスプレイ / DNAマイクロアレイ / ディファレンシャルディスプレイ / マングローブ / 耐塩性 / 窒化ホウ素ナノ粒子 / メソ細孔シリカナノ粒子 / シリコンナノ粒子 / サイトカイン / ナノ粒子 / ドラッグデリバリー / Toll-like receptor 9 / CpGオリゴヌクレオチド / 生物機能工学 … More Except Principal Investigator TLR 9の活性化 / CpG ODN / 細胞毒性 / ドラッグ・デリバリー応用 / 大きな機能性 / 積載能力増強 / 窒化ホウ素ナノ球体 / CpGオリゴヌクレオチド Less

ＤＮＡ医薬による花粉症治療のための溶解性マイクロニードルパッチの開発Principal Investigator
- Principal Investigator
  
  花方信孝
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institute for Materials Science
近赤外発光量子ドットの薬物動態解析および診断への応用Principal Investigator
- Principal Investigator
  
  花方信孝
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institute for Materials Science
細胞質ＤＮＡ受容体を標的としたＤＮＡアジュバントのナノ粒子による作用制御Principal Investigator
- Principal Investigator
  
  花方信孝
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institute for Materials Science
花粉症に対する免疫療法のための窒化ホウ素ナノ粒子の開発
- Principal Investigator
  
  ZHI ChunYi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Inorganic materials/Physical properties
- Research Institution
  National Institute for Materials Science
Delivery system of nucleic acid drug for protection of pollen allergyPrincipal Investigator
- Principal Investigator
  
  HANAGATA Nobutaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  National Institute for Materials Science
Comprehensive gene hunting for salt tolerance from mangrove on the basis of transcriptomePrincipal Investigator
- Principal Investigator
  
  HANAGATA Nobutaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  School of Bionics, Tokyo University of Technology

All 2017 2016 2015 2013 2012 2011 2010

All Journal Article Presentation Patent

[Journal Article] Simplified detection of the hybridized DNA using a graphene field effect transistor.2017
- Author(s)
  M.Arunkumar, S.Chinnathambi, R.Jayavel and N.Hanagata
- Journal Title
  
  Sci. Tech. Adv. Mater.
  
  Volume: 18 Issue: 1 Pages: 43-50
- DOI
  10.1080/14686996.2016.1253408
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15354
[Journal Article] Biocompatible CdSe/ZnS quantum dot micelles for long-term cell imaging without alteration to the native structure of the blood plasma protein human serum albumin2017
- Author(s)
  S. Chinnathambi, Norhidayah Abu, N. Hanagata
- Journal Title
  
  RSC ADVANCES
  
  Volume: 7 Issue: 5 Pages: 2392-2402
- DOI
  10.1039/c6ra26592h
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15354
[Journal Article] Regulation of bifurcated cytokine induction by surface charge of nanoparticles during interaction between CpG oligodeoxynucleotides and toll-like receptor 92015
- Author(s)
  Shanmugavel Chinnathambi, Xiaodong Pi, Mingsheng Xu, Nobutaka Hanagata
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 29 Pages: 251-260
- DOI
  10.1016/j.jddst.2015.08.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15F15354
[Journal Article] Recognition of CpG oligodeoxynucleotides by human Toll-like receptor 9 and subsequent cytokine induction2013
- Author(s)
  S. Suwarti, T. Yamazaki, S. Chechetka, N. Hanagata
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 430 Issue: 4 Pages: 1234-1239
- DOI
  10.1016/j.bbrc.2012.12.068
- NAID
  120005228348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777, KAKENHI-PROJECT-24760655
[Journal Article] Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system2012
- Author(s)
  Hanagata, N
- Journal Title
  
  International Journal of Nanomedicine
  
  Volume: 7 Pages: 2181-2195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] TLR9を介したCpG誘導サイトカインのナノ粒子によるスイッチング2012
- Author(s)
  花方信孝
- Journal Title
  
  アレルギーの臨床
  
  Volume: 32 Pages: 83-87
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Identification of a boron nitride nanosphere-binding peptide for the intracellular delivery of CpG oligodeoxynucleotides2012
- Author(s)
  Zhang H, Yamazaki T, Zhi C, Hanagata N.
- Journal Title
  
  Nanoscale
  
  Volume: 4 Issue: 20 Pages: 6363-6350
- DOI
  10.1039/c2nr31189e
- NAID
  120005306775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23656408
[Journal Article] Effect of molecular weight of polyethyleneimine on loading of CpG oligodeoxynucleotides onto flake-shell silica nanoparticles for enhanced TLR9-mediated induction of interferon-α2012
- Author(s)
  N. Hanagata, Manoharan, Q. Ji, Yamazaki, Shanmugavel, Chen, Ganesan, Hill and Ariga
- Journal Title
  
  Int. J. Nanomed.
  
  Volume: 7 Pages: 3625-3635
- DOI
  10.2147/ijn.s32592
- NAID
  120004448521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Identification of a boron nitride nanosphere-binding peptide for the intracellular delivery of CpG oligodeoxynucleotides2012
- Author(s)
  Zhang H., Yamazaki T., Zhi C., Hanagata N
- Journal Title
  
  Nanoscale
  
  Volume: 4 Pages: 6343-6350
- NAID
  120005306775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] T L R 9を介したC p G誘導サイトカインのナノ粒子によるスイッチング2012
- Author(s)
  Hanagata N.
- Journal Title
  
  アレルギーの臨床
  
  Volume: 32 Pages: 83-87
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system2012
- Author(s)
  N. Hanagata
- Journal Title
  
  Int. J. Nanomed.
  
  Volume: 7 Pages: 2181-2195
- DOI
  10.2147/ijn.s30197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Effect of molecular weight of polyethyleneimine on loading of CpG oligodeoxynucletotides onto flake-shell silica nanoparticles for enhanced TLR9-mediated induction of interferon-α2012
- Author(s)
  Manoharan Y., Ji Q., Yamazaki T., Shanmugavel C., Chen S., Ganesan S., Hill JP., Ariga K., Hanagata N.
- Journal Title
  
  International Journal of Nanomedicine
  
  Volume: 7 Pages: 3625-3635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Binding mode of CpG oligodeoxynucleotides to nanoparticles regulates bifurcated cytokine induction via Toll-like receptor 92012
- Author(s)
  Chinnathambi S., Chen S., Ganesan S., Hanagata N.
- Journal Title
  
  Scientific Reports
  
  Volume: 2(e-pub) Issue: 1 Pages: 534-534
- DOI
  10.1038/srep00534
- NAID
  120004608970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01510, KAKENHI-PROJECT-22560777
[Journal Article] Binding mode of CpG oligodeoxynucleotides to nanoparticles regulates bifurcated cytokine induction via Toll-like receptor 92012
- Author(s)
  Chinnathambi S., Chen S., Ganesan S., Hanagata N
- Journal Title
  
  Scientific Reports
  
  Volume: 2 Pages: 534-534
- NAID
  120004608970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] BN nanospheres as CpG ODN carrier for activation of toll-like receptor 92011
- Author(s)
  Zhi, C., Meng, W., Golberg, D., Tang, C., Hanagata, N.
- Journal Title
  
  Journal of Materials Chemistry
  
  Volume: 21 Pages: 5219-5222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Hollow mesoporous silica/poly(L-lysine) particles for codelivery of drug and gene with enzyme-triggered release property2011
- Author(s)
  Zhu, Y., Meng, W., Gao, H., Hanagata, N.
- Journal Title
  
  The Journal of Physical Chemistry
  
  Volume: 115 Issue: 28 Pages: 13630-13636
- DOI
  10.1021/jp203454g
- NAID
  120003504726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Design of Mesoporous Silica/Cytosine-Phosphodiester-Guanine Oligodeoxynucleotide Complexes To Enhance Delivery Efficiency2011
- Author(s)
  Zhu, Y., Meng, W., Li X., Gao H., Hanagata, N.
- Journal Title
  
  The Journal of Physical Chemistry
  
  Volume: 115 Issue: 2 Pages: 447-452
- DOI
  10.1021/jp109535d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Cytosine-phosphodiester-guanine oligodeoxynucleotide (CpG ODN)-capped hollow mesoporous silica particles for enzyme-triggered drug delivery2011
- Author(s)
  Zhu, Y., Meng, W., Hanagata, N.
- Journal Title
  
  Dalton Transaction
  
  Volume: 40 Pages: 10203-10208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Hollow mesoporous silica/poly(L-lysine) particles for codelivery of drug and gene with enzyme-triggered release property2011
- Author(s)
  Zhu, Y., Meng, W., Gao, H., Hanagata, N.
- Journal Title
  
  The Journal of Physical Chemistry C
  
  Volume: 115 Pages: 13630-13636
- NAID
  120003504726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Design of mesoporous silica/CpG oligonucleaotides complexes for enhancement of delivery efficiency2011
- Author(s)
  Zhu, Y., Meng, W., Li, X., Gao, H., Hanagata,N
- Journal Title
  
  The Journal of Physical Chemistry
  
  Volume: 115 Pages: 447-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Dispersible shortened boron nitride nanotubes with improved molecular-loading capacity2011
- Author(s)
  Zhi, C., Hanagata, N., Bando, Y., Golberg D.
- Journal Title
  
  Chemistry an Asian Journal
  
  Volume: 6 Pages: 2530-2535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Nuclease-resistant immunostimulatory phosphodiester CpG oligodeoxynucleotides as human Toll-like receptor 9 agonists2011
- Author(s)
  Meng, W., Yamazaki, T., Nishida, Y., Hanagata, N
- Journal Title
  
  BMC Biotechnology
  
  Volume: 11 Pages: 88-88
- NAID
  120003444328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] BN nanospheres as CpG ODN carrier for activation of toll-like receptor 92011
- Author(s)
  Zhi, C., Meng, W., Yamazaki, T., Bando, Y., Golberg, D., Tang, C., Hanagata, N
- Journal Title
  
  Journal of Materials Chemistry
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Journal Article] Nuclease-resistant immunostimulatory phosphodiester CpG oligodeoxynucleotides as human Toll-like receptor 9 agonists2011
- Author(s)
  Meng, W., Yamazaki, T., Nishida, Y., Hanagata, N.
- Journal Title
  
  BMC Biotechnology
  
  Volume: 11 Issue: 1 Pages: 88-96
- DOI
  10.1186/1472-6750-11-88
- NAID
  120003444328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22560777
[Patent] 免疫刺激オリゴヌクレオチドおよび前記免疫刺激オリゴヌクレオチドを含む治療剤2011
- Inventor(s)
  山崎智彦、花方信孝
- Industrial Property Rights Holder
  独立行政法人物質・材料研究機構
- Industrial Property Number
  2011-070049
- Filing Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Gelatin Microneedles As a Transdermal Delivery System for Adjuvant CpG DNA.2017
- Author(s)
  CHEN, Min-Hua, MINOWA, Takashi, LI, Xianglan, HANAGATA, Nobutaka.
- Organizer
  The 15th International Conference on Advanced Materials (UMRS-ICAM2017)
- Place of Presentation
  Ｋｙｏｔｏ　Ｕｎｉｖｅｒｓｉｔｙ、Ｋｙｏｔｏ，　Ｊａｐａｎ
- Year and Date
  2017-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16356
[Presentation] Quantum dot micelles for cancer cell imaging2017
- Author(s)
  CHINNATHAMBI, Shanmugavel, HANAGATA, Nobutaka
- Organizer
  UMRS-ICAM2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15354
[Presentation] Apatite Nanoparticles-Assisted Gelatin Microneedles for Transdermal Adjuvant CpG DNA Delivery2017
- Author(s)
  CHEN, Min-Hua, MINOWA, Takashi, LI, Xianglan, HANAGATA, Nobutaka
- Organizer
  The 15th International Conference on Advanced Materials (UMRS-ICAM2017)
- Place of Presentation
  Ｋｙｏｔｏ　Ｕｎｉｖｅｒｓｉｔｙ，　Ｋｙｏｔｏ，　Ｊａｐａｎ
- Year and Date
  2017-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16356
[Presentation] Superparamagnetic CdSe/ZnS Quantum Dot Micelles for Cancer Cell Imaging2016
- Author(s)
  S. Chinnathambi, N. Hanagata
- Organizer
  Advanced materials conference 2016
- Place of Presentation
  The Bayview Hotel Langkawi, Langkawi, Malaysia
- Year and Date
  2016-11-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15354
[Presentation] Dissolving Microneedles As a Transdermal Delivery System for Adjuvant CpG DNA2016
- Author(s)
  M. Chen, M. Takashi, X. LI, T. Takemura, N. Hanagata
- Organizer
  Advanced materials conference 2016
- Place of Presentation
  The Bayview Hotel Langkawi, Langkawi, Malaysia
- Year and Date
  2016-11-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16356
[Presentation] Apatite Nanoparticles-Assisted Dissolving Microneedles for Transdermal Adjuvant CpG DNA Delivery2016
- Author(s)
  M. Chen, M. Takashi, Abigail Magee, X. LI, T. Takemura, N. Hanagata
- Organizer
  10th Anniversary International Symposium on Nanomedicine
- Place of Presentation
  National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
- Year and Date
  2016-11-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16356
[Presentation] Functionalized Near-Infrared Quantum Dots for Biological Applications2016
- Author(s)
  Shanmugavel Chinnathambi and Hanagata Nobutaka
- Organizer
  8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery System
- Place of Presentation
  Madrid, Spain
- Year and Date
  2016-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15354
[Presentation] Superparamagnetic CdSe/ZnS Quantum Dot Micelles2016
- Author(s)
  S. Chinnathambi, N. Hanagata
- Organizer
  10th Anniversary International Symposium on Nanomedicine
- Place of Presentation
  National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
- Year and Date
  2016-11-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15354
[Presentation] Micelle Encapsulated Magnetic Core / Shell Quantum Dots for Biological Applications2015
- Author(s)
  Shanmugavel Chinnathambi and Hanagata Nobutaka
- Organizer
  9th International Symposium of Nanomedicine
- Place of Presentation
  Mie, Japan
- Year and Date
  2015-12-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15354
[Presentation] Regulation of bifurcated cytokine induction by binding mode of CpG DNA onto nanoparticles2013
- Author(s)
  N. Hanagata
- Organizer
  5th Immunotherapeutics & Immunomonitoring Conference
- Place of Presentation
  The Westin Gaslamp Quarter San Diego, USA
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Regulation of Toll-like Receptor 9 mediated Cytokine Profile by Binding Mode of CpG Oligodeoxynucleotides to Nanoparticles2012
- Author(s)
  Hanagata, N
- Organizer
  1st International Conference on Emerging Advanced Nanomaterials (ICEAN 2012)
- Place of Presentation
  Mercure Hotel, Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Preparation and characterization of silicon quantum dots for delivery of nucleic acid drugs. 4th International Conference on Advanced Nanomaterials (ANM2012)2012
- Author(s)
  Shanmugavel, C., Ganesan S., Hanagata, N
- Organizer
  Indian Institute of Technology Madras (IIT Madras)
- Place of Presentation
  Chennai, India
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] N. New Nuclease-Resistant Immunostimulatory Phosphodiester-based Oligonucleotides for Immune Therapies2012
- Author(s)
  Yamazaki, T.,Meng W., Hanagata
- Organizer
  The 9th World Biomaterials Congress (WBC)
- Place of Presentation
  Sichuan University,Sichuan China
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Regulation of Toll-like Receptor 9 mediated Cytokine Profile by Binding Mode of CpG Oligodeoxynucleotides to Nanoparticles2012
- Author(s)
  Hanagata, N.
- Organizer
  1st International Conference on Emerging Advanced Nanomaterials
- Place of Presentation
  Mercure Hotel, Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Identification of a specific binding peptide to boron nitride nanospheres for delivery of CpG oligodeoxynucleotides2012
- Author(s)
  Zhang, H., Yamazaki, T., i Zhi, C., Hanagata, N.
- Organizer
  第6回ナノバイオメディカル学会大会
- Place of Presentation
  独立行政法人産業技術総合研究所
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Characterization of interleukin-6 induction by natural CpG oligodeoxynuxleotide2012
- Author(s)
  Chechetka, S., Yamazaki, T., Hanagata, N.
- Organizer
  第6回ナノバイオメディカル学会大会
- Place of Presentation
  独立行政法人産業技術総合研究所
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Synthesis and characterization of positively charged silicon quantum dots for delivery of nucleic acid drugs2012
- Author(s)
  Shanmugavel, C., Hanagata, N
- Organizer
  第6回ナノバイオメディカル学会大会
- Place of Presentation
  独立行政法人産業技術総合研究所
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Effect of interaction mode of CpG oligodeoxynucleotides with TLR9 on bifurcated cytokine induction2012
- Author(s)
  Shanmugavel, C., Hanagata, N
- Organizer
  第6回ナノバイオメディカル学会大会
- Place of Presentation
  独立行政法人産業技術総合研究所
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Response of human lung epithelial cells to the toxicity of zinc oxide nanoparticles2012
- Author(s)
  Zhuang, F.,Hanagata, N.
- Organizer
  第6回ナノバイオメディカル学会大会
- Place of Presentation
  独立行政法人産業技術総合研究所
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Preparation and characterization of silicon quantum dots for delivery of nucleic acid drugs2012
- Author(s)
  7.Shanmugavel, C., Ganesan S., Hanagata
- Organizer
  4th International Conference on Advanced Nanomaterials(ANM2012)
- Place of Presentation
  Indian Institute of Technology Madras
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] BN nanospheres as CpG ODN carrier for activation of toll-like receptor 92011
- Author(s)
  Zhi, C., Meng, W., Yamazaki, T., Bando, Y., Golberg, D., Tang, C., Hanagata, N.
- Organizer
  ナノ・バイオメディカル学会
- Place of Presentation
  名古屋大学野依記念学術交流会館(愛知県)
- Year and Date
  2011-02-22
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Construction of nuclear-resistant phosphodiester CpG oligonucleotides for pollinosis therapy2011
- Author(s)
  Meng, W., Yamazaki, T., Hanagata, N.
- Organizer
  ナノ・バイオメディカル学会
- Place of Presentation
  名古屋大学野依記念学術交流会館
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Construction of nuclear-resistant phosphodiester CpG oligonucleotides for pollinosis therapy2011
- Author(s)
  Meng, W., Yamazaki, T., Hanagata, N.
- Organizer
  ナノ・バイオメディカル学会
- Place of Presentation
  名古屋大学野依記念学術交流会館(愛知県)
- Year and Date
  2011-02-22
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Molecular organization at the live cell-biomembrane interface2011
- Author(s)
  Zhang, L., Kaizuka, Y., Hanagata, N.
- Organizer
  ナノ・バイオメディカル学会
- Place of Presentation
  名古屋大学野依記念学術交流会館
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] BN nanospheres as CpG ODN carrier for activation of toll-like receptor 92011
- Author(s)
  Zhi, C., Meng, W., Yamazaki, T., Bando, Y., Golberg, D., Tang, C., Hanagata, N.
- Organizer
  ナノ・バイオメディカル学会
- Place of Presentation
  名古屋大学野依記念学術交流会館
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Fe3O4@Sio2 hollow mesoporous spheres as potential carrier for anticancer drug delivery2011
- Author(s)
  Zhu, Y., Hanagata, N
- Organizer
  ナノ・バイオメディカル学会
- Place of Presentation
  名古屋大学野依記念学術交流会館(愛知県)
- Year and Date
  2011-02-22
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] CpG oligodeoxynucleotide and its delivery system2011
- Author(s)
  Yamazaki, Y., Meng, W., Zhi, C., Zhu, Y., Hanagata, N.
- Organizer
  9th annual Bio Nanotech Conference
- Place of Presentation
  Boston, US
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Enhancement of the theraqeutic efficiency of a human toll-lilke receptor 9 agonist via bio-and nano-technology2011
- Author(s)
  Yamazaki, T. Hanagata, N.
- Organizer
  International Workshop on Biomedical Sciences and Technologies
- Place of Presentation
  Anna University, Chennai, India
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Novel CpG oligodeoxynucleotide and its delivery system2011
- Author(s)
  Yamazaki, Y., Meng, W., Zhi, C., Zhu, Y., Hanagata, N.
- Organizer
  9th annual Bio Nanotech Conference
- Place of Presentation
  Boston, US
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Identification of Boron Nitride Nanospheres Binding Peptides2011
- Author(s)
  Zhang, H., Yamazaki, T., Zhi, C., Hanagata, N.
- Organizer
  The Symposium on Micro/Nano Aspects of Biomaterials
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Novel CpG phosphodiester oligodeoxynucleotides as human toll-like receptor 9 agonists2011
- Author(s)
  Yamazaki, T., Meng, W., Hanagata, N.
- Organizer
  Infection and Immunity (Cold Spring Harbor Asia)
- Place of Presentation
  Suzhou Dushu Lake Conference Center, Shuzou, China
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Analysis of CpG ODNS binding of human toll like receptor 92011
- Author(s)
  Suwarti, Yamazaki, T., Hanagata, N.
- Organizer
  Infection and Immunity (Cold Spring Harbor Asia)
- Place of Presentation
  Suzhou Dushu Lake Conference Center, Shuzou, China
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Design of mesoporous silica/CpG ODN complexes to enhance delivery efficiency2011
- Author(s)
  Zhu, Y., Hanagata, N.
- Organizer
  International Conference on Materials for Advanced technologies
- Place of Presentation
  Suntec Singapore Hotel, Singapore
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Water soluble silicon quantum dots as fluorescent probes for bio-applications2011
- Author(s)
  Chinnathambi S., Krishnan, V., Ariga, K., Hanagata, N.
- Organizer
  The Symposium on Micro/Nano Aspects of Biomaterials
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Novel CpG phosphodiester oligodeoxynucleotides as human toll-like receptor 9 agonists2011
- Author(s)
  Yamazaki, T., Meng, W., Hanagata, N.
- Organizer
  Infection and Immunity (Cold Spring Harbor Asia)
- Place of Presentation
  Dushu Lake Conference Center, Shuzou, China
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Analysis of CpG ODNS binding of human toll like receptor 92011
- Author(s)
  Suwarti, Yamazaki, T., Hanagata, N.
- Organizer
  Infection and Immunity (Cold Spring Harbor Asia)
- Place of Presentation
  Dushu Lake Conference Center, Shuzou, China
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Design of mesoporous silica/CpG ODN complexes to enhance delivery efficiency. International Conference on Materials for Advanced2011
- Author(s)
  Zhu, Y., Hanagata, N.
- Organizer
  International Conference on Materials for Advanced technologies
- Place of Presentation
  Suntec Singapore Hotel, Singapore
- Year and Date
  2011-06-26
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Fe3O4@Sio2 hollow mesoporous spheres as potential carrier for anticancer drug delivery2011
- Author(s)
  Zhu, Y., Hanagata, N.
- Organizer
  ナノ・バイオメディカル学会
- Place of Presentation
  名古屋大学野依記念学術交流会館
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Novel Phosphodiester CpG Oligodeoxynucleotides with High Stimulatory Effects on Human Toll-like Receptor 92011
- Author(s)
  Meng, W., Yamazaki, T., Hanagata, N.
- Organizer
  The Symposium on Micro/Nano Aspects of Biomaterials
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] C-terminal ligand binding analysis of human Toll-like receptor 92011
- Author(s)
  Suwarti, Yamazaki, T., Hanagata, N.
- Organizer
  The Symposium on Micro/Nano Aspects of Biomaterials
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Rattle-type Fe3O4@Sio2 hollow mesoporous spheres as potential carriers for anti-cancer drug delivery2010
- Author(s)
  Zhu, Y., Hanagata, N
- Organizer
  The 10th Asia Bioceramics Symposium
- Place of Presentation
  Yogyakarta, Indonesia
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Modified hollow mesopheres as carriers for targeted drug delivery2010
- Author(s)
  Zhu, Y., Hanagata, N., Kobayashi, H
- Organizer
  11th IUMRS International Conference in Asia
- Place of Presentation
  Qingdao International Convention Center, Qingdao, China
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22560777
[Presentation] Hollow mesoporous silica spheres as carrier for drug delivery2010
- Author(s)
  Zhu, Y., Hanagata, N
- Organizer
  8th Annual Congress of International Drug Discovery Science
- Place of Presentation
  Beijing International Convention Center, Beijin, China
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-22560777

1. OH HWAN HEE

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. SASAKI Satoshi (70262110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ZHI ChunYi (50469764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 坂東義雄 (10344433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. CHINNATHAMBI SHANMUGAVEL

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
6. CHEN MIN-HUA

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. CHEN Song

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

HANAGATA Nobutaka 花方 信孝

花方 信孝 ハナガタ ノブタカ

Research Projects

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Co-Researchers

ＤＮＡ医薬による花粉症治療のための溶解性マイクロニードルパッチの開発Principal Investigator

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近赤外発光量子ドットの薬物動態解析および診断への応用Principal Investigator

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細胞質ＤＮＡ受容体を標的としたＤＮＡアジュバントのナノ粒子による作用制御Principal Investigator

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花粉症に対する免疫療法のための窒化ホウ素ナノ粒子の開発

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Delivery system of nucleic acid drug for protection of pollen allergyPrincipal Investigator

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Comprehensive gene hunting for salt tolerance from mangrove on the basis of transcriptomePrincipal Investigator

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[Journal Article] Simplified detection of the hybridized DNA using a graphene field effect transistor.2017

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[Journal Article] Biocompatible CdSe/ZnS quantum dot micelles for long-term cell imaging without alteration to the native structure of the blood plasma protein human serum albumin2017

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[Journal Article] Regulation of bifurcated cytokine induction by surface charge of nanoparticles during interaction between CpG oligodeoxynucleotides and toll-like receptor 92015

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[Journal Article] Recognition of CpG oligodeoxynucleotides by human Toll-like receptor 9 and subsequent cytokine induction2013

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NAID

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[Journal Article] Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system2012

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[Journal Article] TLR9を介したCpG誘導サイトカインのナノ粒子によるスイッチング2012

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[Journal Article] Identification of a boron nitride nanosphere-binding peptide for the intracellular delivery of CpG oligodeoxynucleotides2012

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NAID

Data Source

[Journal Article] Effect of molecular weight of polyethyleneimine on loading of CpG oligodeoxynucleotides onto flake-shell silica nanoparticles for enhanced TLR9-mediated induction of interferon-α2012

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DOI

HANAGATA Nobutaka 花方信孝

花方信孝ハナガタノブタカ