KAWASHIMA Toshiyuki 川島敏行

Researcher Number	10306839
Other IDs
Affiliation (based on the past Project Information) *help	2007 – 2010: The University of Tokyo, 医科学研究所, 助教 2004 – 2006: 東京大学, 医科学研究所, 助手
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Biological Sciences / Hematology
Keywords	Principal Investigator GAP / CENP / キネトコア / シグナル伝達 / 生体分子 / two-hybrid / microtubules / sister chromosome / cytokinesis / kinetochore … More / ツーハイブリッド法 / 微小管 / 姉妹染色体 / 細胞質分裂 / 動原体 / 細胞増殖 / 転写因子 / 癌化 / 転写 / 染色体 / MgcRacGAP / 細胞分裂 / 発生・分化 … More Except Principal Investigator 転写因子 / STAT / STAT3 / GAP / Rac1 / STAT5 / サイトキネシス / 低分子量G蛋白質 / 細胞分裂 / 低分子化合物 / 癌 / PhoA / Cytokinesis / importin / nuclear transport assay / GAP蛋白質 / 転写 / RhoA / 細胞質分裂 / インポーチン / 核移行アッセイ / G蛋白質 / 細胞分化 / IL6 / IL-6 / 阻害剤 Less

新規RacGAPの細胞癌化における機能解析Principal Investigator
- Principal Investigator
  
  川島敏行
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
シグナル伝達系阻害薬の同定と分子標的療法への応用
- Principal Investigator
  
  北村俊雄
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
MgcRacGAPによる細胞周期と増殖分化の統合的調節機構の解析
- Principal Investigator
  
  北村俊雄
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Roles of a novel kinetochore protein CENP-50 in the transcriptionalregulation and chromosome dividingPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Toshiyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
STAT3を標的とした分子標的療法をめざして
- Principal Investigator
  
  KITAMURA Toshio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Characterization of a novel kinetochore protein that are involved in cell growth and differentiation.Principal Investigator
- Principal Investigator
  
  KAWASHIMA Toshiyuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Crosstalk between STATs and small GTPases in the control of cell division and differentiation.
- Principal Investigator
  
  KITAMURA Toshio
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

All 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] A Rae GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009
- Author(s)
  Toshiyuki Kawashima
- Journal Title
  
  Molecular and Cellular Biology 29
  
  Pages: 1796-1813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591097
[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009
- Author(s)
  Kawashima, T
- Journal Title
  
  Mol Cell Biol. 29
  
  Pages: 1796-1813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015011
[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009
- Author(s)
  Kawashima T
- Journal Title
  
  Molecular and Cellular Biology 29
  
  Pages: 1796-1813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015011
[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors.2009
- Author(s)
  Kawashima, T
- Journal Title
  
  Mol Cell Biol. 29
  
  Pages: 1796-1813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591192
[Journal Article] A Rac GTPase activating protein MgcRacGAPis an NLS-containing nuclear chaperone in theactivation of STAT transcription factors2009
- Author(s)
  Toshiyuki Kawashima,Ying Chun Bao,Yukinori Minoshima, Yasushi Nomura,Tomonori Hatori, Tetsuya Hori, TatsuoFukagawa, Toshiyuki Fukada, NorikoTakahashi, Tetsuya Nosaka, Makoto Inoue,Tomohiro Sato, Mutsuko Kukimoto-Niino,Mikako Shirouzu, Shigeyuki Yokoyama and Toshio Kitamura
- Journal Title
  
  Molecular and Cellular Biology 29
  
  Pages: 1796-813
- Data Source
  KAKENHI-PROJECT-19591097
[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009
- Author(s)
  Kawashima, T
- Journal Title
  
  Mol Cell Biol. 29
  
  Pages: 1796-1813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058006
[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors2008
- Author(s)
  Toshiyuki Kawashima
- Journal Title
  
  Methods in Enzymology 439
  
  Pages: 171-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591097
[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors2008
- Author(s)
  Kawashima T
- Journal Title
  
  Methods in Enzymology 439
  
  Pages: 171-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058006
[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors2008
- Author(s)
  Kawashima T
- Journal Title
  
  Methods in Enzymology 439
  
  Pages: 171-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015011
[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2008
- Author(s)
  Kawashima T
- Journal Title
  
  Molecular and Cellular Biology 29
  
  Pages: 1796-1813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058006
[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors2008
- Author(s)
  Toshiyuki Kawashima and Toshio Kitamura
- Journal Title
  
  Methods in Enzymology 439
  
  Pages: 171-189
- Data Source
  KAKENHI-PROJECT-19591097
[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors.2008
- Author(s)
  川島敏行
- Journal Title
  
  Methods in Enzymology 431
  
  Pages: 171-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015010
[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors.2008
- Author(s)
  川島敏行
- Journal Title
  
  Methods in Enzymology 431
  
  Pages: 171-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591097
[Journal Article] Rac1 and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  川島敏行
- Journal Title
  
  J. Cell Biol. 175
  
  Pages: 937-946
- Data Source
  KAKENHI-PROJECT-18015010
[Journal Article] Racl and a GTPase activating protein MgcRacGAp are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  川島敏行
- Journal Title
  
  J. Cell Biol. 175
  
  Pages: 937-946
- Data Source
  KAKENHI-PROJECT-16209032
[Journal Article] Rac1 and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  Kawashima, T, et al.
- Journal Title
  
  J.Cell.Biol. 175
  
  Pages: 937-946
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590980
[Journal Article] Racl and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  川島敏行
- Journal Title
  
  J. Cell Biol. 175
  
  Pages: 937-946
- Data Source
  KAKENHI-PROJECT-17590980
[Journal Article] Rac1 and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  Kawashima, T., et al.
- Journal Title
  
  J. Cell Biol. 175
  
  Pages: 937-946
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209032
[Journal Article] Racl and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  Kawashima. T et al.
- Journal Title
  
  J. Cell Biol. 175
  
  Pages: 937-946
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209032
[Journal Article] Rac1 and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  Kawashima. T et al.
- Journal Title
  
  J. Cell Biol. 175
  
  Pages: 937-946
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590980
[Presentation] 新しいメカニズムでJAK/STATシグナルを抑制する阻害剤の同定2008
- Author(s)
  川島敏行
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20015011
[Presentation] 新しいメカニズムでJAK/STATシグナルを抑制する阻害剤の同定2008
- Author(s)
  川島敏行
- Organizer
  日本血液学会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19591097
[Presentation] 新しいメカニズムでJAK/STATシグナルを抑制する阻害剤の同定2008
- Author(s)
  川島敏行、土屋秋穂、北村俊雄
- Organizer
  日本血液学会シンポジウム
- Place of Presentation
  国立京都国際会館
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19591097
[Presentation] 新しいメカニズムでJAK/STATシグナルを抑制する阻害剤の同定2008
- Author(s)
  川島敏行
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20058006
[Presentation] STAT3/5の活性化メカニズムと分子標的療法2007
- Author(s)
  川島敏行
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591097
[Presentation] STAT3/5の活性化メカニズムと分子標的療法2007
- Author(s)
  川島敏行
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18015010

1. KITAMURA Toshio (20282527)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. NOSAKA Tetsuya (30218309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAKAJIMA Hideaki (30217723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWASHIMA Toshiyuki 川島 敏行

Research Projects

Research Products

Co-Researchers

新規RacGAPの細胞癌化における機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

シグナル伝達系阻害薬の同定と分子標的療法への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

MgcRacGAPによる細胞周期と増殖分化の統合的調節機構の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of a novel kinetochore protein CENP-50 in the transcriptionalregulation and chromosome dividingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STAT3を標的とした分子標的療法をめざして

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of a novel kinetochore protein that are involved in cell growth and differentiation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Crosstalk between STATs and small GTPases in the control of cell division and differentiation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A Rae GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009

Author(s)

Journal Title

Data Source

[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009

Author(s)

Journal Title

Data Source

[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009

Author(s)

Journal Title

Data Source

[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors.2009

Author(s)

Journal Title

Data Source

[Journal Article] A Rac GTPase activating protein MgcRacGAPis an NLS-containing nuclear chaperone in theactivation of STAT transcription factors2009

Author(s)

Journal Title

Data Source

[Journal Article] A Rac GTPase activating protein MgcRacGAP is an NLS-containing nuclear chaperone in the activation of STAT transcription factors2009

Author(s)

Journal Title

Data Source

[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors2008

Author(s)

Journal Title

Data Source

[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors2008

Author(s)

Journal Title

Data Source

[Journal Article] Rac and Nuclear Translocation of STAT Transcription Factors2008

Author(s)

KAWASHIMA Toshiyuki 川島敏行