OOBOSHI Hiroaki 大星博明

Researcher Number	10311838
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2017: 福岡歯科大学, 口腔歯学部, 教授 2011 – 2015: 福岡歯科大学, 歯学部, 教授 2008: Kyushu University, 大学病院, 講師 2007: Kyushu University, 大学病院, 助教 2003: Kyushu University, Kyushu University Hospital, Assistant Professor, 大学病院, 助手 2002: 九州大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Neurology / Neurology
Keywords	Principal Investigator 遺伝子治療 / 脳梗塞 / 自然免疫 / マクロファージ / DAMPs / 脳虚血 / 遺伝子導入 / interleukin-10 / inflammatory signal / adenoviral vector … More / stroke / gene therapy / インターロイキン10 / 炎症シグナル / アデノウイルスベクター / 脳血管障害 / 周皮細胞 / スカベンジャー受容体 / インターロイキン / T細胞 / 免疫 / 炎症 / peroxiredoxin / γδT細胞 / インターロイキン17 / インターロイキン23 / Peroxiredoxin / TLR / センダイウイルス / 血管透過性 / ベクター Less

Research on therapy for brain infarction targeting innate immunityPrincipal Investigator
- Principal Investigator
  
  Ooboshi Hiroaki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Fukuoka Dental College
Targeting inflammation-immune response as a novel strategy for the treatment of brain infarctionPrincipal Investigator
- Principal Investigator
  
  OOBOSHI Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Fukuoka Dental College
Gene therapy with Sendai virus vector ta rgeting for microcirculatory construct in brain infarctionPrincipal Investigator
- Principal Investigator
  
  OOBOSHI Hiroaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Gene therapy against ischemic stroke targeting inflammatory signalsPrincipal Investigator
- Principal Investigator
  
  OOBOSHI Hiroaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University

All 2018 2017 2016 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 脳卒中病態学のススメ2018
- Author(s)
  大星博明
- Total Pages
  354
- Publisher
  南山堂
- ISBN
  9784525248512
- Data Source
  KAKENHI-PROJECT-26461301
[Book] Acute brain impairment2017
- Author(s)
  Ooboshi H
- Total Pages
  348
- Publisher
  Royal Society of Chemistry
- ISBN
  9781782629504
- Data Source
  KAKENHI-PROJECT-26461301
[Book] DAMPs (damage-associated molecular patterns)と炎症. 脳卒中 -新時代の治療を求めて-2016
- Author(s)
  大星博明、七田崇
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26461301
[Book] 無症候性脳出血とmicrobleeds.脳血管障害の治療最前線2014
- Author(s)
  大星博明
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23591262
[Book] 脳出血慢性期の治療. 最最新臨床脳卒中学(下)2014
- Author(s)
  大星博明
- Total Pages
  711
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26461301
[Book] 虚血による神経障害のメカニズム-脳梗塞と炎症. 最新臨床脳卒中学(上)2014
- Author(s)
  七田崇、吉村昭彦、大星博明
- Total Pages
  735
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26461301
[Book] 無症候性脳出血とmicrobleeds. 脳血管障害治療最前線2014
- Author(s)
  大星博明
- Total Pages
  421
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-26461301
[Book] Midkine gene transfer in brain infarction. Chap 13, Midkine : From Embryogenesis to Pathogenesis and Therapy2012
- Author(s)
  Ooboshi H, Ishikawa E, Takada J, Shichita T, Kumai Y
- Total Pages
  38
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23591262
[Book] Midkine gene transfer in brain infarction. Ch 13, Midkine: From Embryogenesis to Pathogenesis and Therapy2012
- Author(s)
  Ooboshi H, Ishikawa E, Takada J, Shichita T, Kumai Y.
- Total Pages
  380
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23591262
[Book] Midkine: From Embryogenesis to Pathogenesis and Therapy, in press Springer Science2012
- Author(s)
  Ooboshi H, Ishikawa E, Takada J, Shichita T, Kumai Y
- Total Pages
  380
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23591262
[Book] Potentilas of gene therapy for neuroprotection and neurogenesis inbrain ischemia. In Recent Advances in Neurogenesis, Neuroproregeneration and Neuroprotection2009
- Author(s)
  Ooboshi H, et al
- Total Pages
  13
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-19590993
[Book] Recent Advances in Neurogenesis
- Author(s)
  Ooboshi H, Ishikawa E, Kumai Y, Shichita T, Takada J, Ibayashi S
- Publisher
  Research Signpost : Potentials of gene therapy for neuroprotection and neurogenesis in brain ischemia(in press)
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Secular trends in the incidence of end-stage renal disease and its risk factors in Japanese patients with immunoglobulin A nephropathy.2018
- Author(s)
  Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 印刷中 Issue: 6 Pages: 963-971
- DOI
  10.1093/ndt/gfx223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-16K11066
[Journal Article] Total phosphate elimination is negatively associated with increased serum fibroblast growth factor 23 levels in patients who undergo peritoneal dialysis2017
- Author(s)
  Yamada S, Tsuruya K, Tokumoto M, Yoshida H, Tatsumoto N, Ooboshi H, Kitazono T
- Journal Title
  
  Ther Apher Dial
  
  Volume: 21 Issue: 1 Pages: 71-78
- DOI
  10.1111/1744-9987.12478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Association Between Onset-to-Door Time and Clinical Outcomes After Ischemic Stroke2017
- Author(s)
  Matsuo Ryu、Yamaguchi Yuko、Matsushita Tomonaga、Hata Jun、Kiyuna Fumi、Fukuda Kenji、Wakisaka Yoshinobu、Kuroda Junya、Ago Tetsuro、Kitazono Takanari、Kamouchi Masahiro、on behalf of the Fukuoka Stroke Registry Investigators†
- Journal Title
  
  Stroke
  
  Volume: 48 Issue: 11 Pages: 3049-3056
- DOI
  10.1161/strokeaha.117.018132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04143, KAKENHI-PROJECT-15K08849, KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-26462163
[Journal Article] Mafb prevents excess inflammation after ischemic stroke by accelerating clearance of danger signals through MSR1.2017
- Author(s)
  1)Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A.
- Journal Title
  
  Nat Med.
  
  Volume: in press Issue: 6 Pages: 723-732
- DOI
  10.1038/nm.4312
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01387, KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-16H05178, KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-17K19571, KAKENHI-PUBLICLY-17H05514, KAKENHI-PROJECT-17H05096, KAKENHI-PROJECT-16H06276
[Journal Article] Hypercalcemia induced acute kidney injury in an elderly patient with osteoporosis who received alphacalcidol in response to denosumab-induced hypocalcemia.2017
- Author(s)
  Yamada S, Matsuo M, Tokumoto M, Ooboshi H
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: 22 Issue: 7 Pages: 572-573
- DOI
  10.1111/nep.12843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Impact of blood urea nitrogen to creatinine ratio on mortality and morbidity in hemodialysis patients: The Q-Cohort Study.2017
- Author(s)
  Tanaka S, Ninomiya T, Taniguchi M, Tokumoto M, Masutani K, Ooboshi H, Kitazono T, Tsuruya K.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 14910-14910
- DOI
  10.1038/s41598-017-14205-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11066, KAKENHI-PROJECT-26461301
[Journal Article] Very low protein diet enhances inflammation, malnutrition, and vascular calcification in uremic rats.2016
- Author(s)
  Yamada S, Tokumoto M, Tatsumoto N, Tsuruya K, Kitazono T, Ooboshi H
- Journal Title
  
  Life Sci
  
  Volume: 146 Pages: 117-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Pseudohyperchloraemia caused by long-term use of analgesic containing bromovaleryl urea.2016
- Author(s)
  Yamada S, Tokumoto M, Ooboshi H
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: 21 Issue: 2 Pages: 161-2
- DOI
  10.1111/nep.12566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] DAMPs (damage-associated molecular patterns)と炎症2016
- Author(s)
  大星博明、七田崇
- Journal Title
  
  日本臨床
  
  Volume: 74 Pages: 573-578
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Comparison of oral versus intravenous vitamin D receptor activator in reducing infection-related mortality in hemodialysis patients: the Q-Cohort Study2016
- Author(s)
  Tanaka S, Ninomiya T, Taniguchi M, Fujisaki K, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 31 Issue: 7 Pages: 1152-1160
- DOI
  10.1093/ndt/gfw205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Possible involvement of basic FGF in the upregulation of PDGFRβ in pericytes after ischemic stroke2016
- Author(s)
  Nakamura K, Arimura K, Nishimura A, Tachibana M, Yoshikawa Y, Makihara N, Wakisaka Y, Kuroda J, Kamouchi M, Ooboshi H, Kitazono T, Ago T
- Journal Title
  
  Brain Research
  
  Volume: 1630 Pages: 98-108
- DOI
  10.1016/j.brainres.2015.11.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461134, KAKENHI-PROJECT-26461145, KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-26462163
[Journal Article] Factors associated with the serum myostatin level in patients undergoing peritoneal dialysis: potential effects of skeletal muscle mass and vitamin d receptor activator use2016
- Author(s)
  Yamada S, Tsuruya K, Yoshida H, Tokumoto M, Ueki K, Ooboshi H, Kitazono T
- Journal Title
  
  Calcif Tissue Int
  
  Volume: 99 Issue: 1 Pages: 13-22
- DOI
  10.1007/s00223-016-0118-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Factors associated with serum soluble inhibitors of Wnt-β-catenin signaling (sclerostin and dickkopf-1) in patients undergoing peritoneal dialysis.2015
- Author(s)
  Yamada S, Tsuruya K, Tokumoto M, Yoshida H, Ooboshi H, Kitazono T
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: 20 Issue: 4 Pages: 639-45
- DOI
  10.1111/1744-9987.12292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Fetuin-A decrease induced by a low-protein diet enhances vascular calcification in uremic rats with hyperphosphatemia.2015
- Author(s)
  Yamada S, Tokumoto M, Tsuruya K, Tatsumoto N, Noguchi H, Kitazono T, Ooboshi H
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 309 Issue: 8 Pages: F744-F754
- DOI
  10.1152/ajprenal.00017.2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Day-by-Day Blood Pressure Variability and Functional Outcome After Acute Ischemic Stroke: Fukuoka Stroke Registry2015
- Author(s)
  Fukuda K, Kai H, Kamouchi M, Hata J, Ago T, Nakane H, Imaizumi T, Kitazono T
- Journal Title
  
  Stroke
  
  Volume: 46 Issue: 7 Pages: 1832-1839
- DOI
  10.1161/strokeaha.115.009076
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460756, KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-26293158
[Journal Article] Phosphate binders prevent phosphate-induced cellular senescence of vascular smooth muscle cells and vascular calcification in a modified, adenine-based uremic rat model.2015
- Author(s)
  Yamada S, Tatsumoto N, Tokumoto M, Noguchi H, Ooboshi H, Kitazono T, Tsuruya K
- Journal Title
  
  Calcif Tissue Int
  
  Volume: 96 Issue: 4 Pages: 347-358
- DOI
  10.1007/s00223-014-9929-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Fibroblast growth factor 23, but not parathyroid hormone, is associated with urinary phosphate regulation in patients on peritoneal dialysis.2015
- Author(s)
  Yamada S, Tsuruya K, Tokumoto M, Yoshida H, Hasegawa S, Tanaka S, Eriguchi M, Nakano T, Masutani K, Ooboshi H, Kitazono T
- Journal Title
  
  Ther Apher Dial
  
  Volume: 19 Issue: 1 Pages: 73-80
- DOI
  10.1111/1744-9987.12221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] A CADASIL-like case with a novel noncysteine mutation of the NOTCH3 gene and granular deposits in the renal arterioles.2015
- Author(s)
  Nakamura K, Ago T, Tsuchimoto A, Noda N, Nakamura A, Ninomiya T, Uchiumi T, Tsuruya K, Kamouchi M, Ooboshi H, Kitazono T
- Journal Title
  
  Case Rep Neurol Med
  
  Volume: 2015 Pages: 431461-431461
- DOI
  10.1155/2015/431461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-26861169
[Journal Article] ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and long-term risks of stroke after transient ischemic attack.2014
- Author(s)
  Kiyohara T, Kamouchi M, Kumai Y, Ninomiya T, Hata J, Yoshimura S, Ago T, Okada Y, Kitazono T; Fukuoka Stroke Registry Investigators (Ooboshi H).
- Journal Title
  
  Stroke
  
  Volume: 45 Issue: 2 Pages: 418-25
- DOI
  10.1161/strokeaha.113.003077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591262, KAKENHI-PROJECT-26293158
[Journal Article] Phosphate overload directly induces systemic inflammation and malnutrition as well as vascular calcification in uremia.2014
- Author(s)
  Yamada S, Tokumoto M, Tatsumoto N, Taniguchi M, Noguchi H, Nakano T, Masutani K, Ooboshi H, Tsuruya K, Kitazono T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 306 Issue: 12 Pages: F1418-F1428
- DOI
  10.1152/ajprenal.00633.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461301
[Journal Article] Plasma S100A12 is associated with functional outcome after ischemic stroke : Research for Biomarkers in Ischemic Stroke2014
- Author(s)
  Wakisaka Y, Ago T, Kamouchi M, Kuroda J, Matsuo R, Hata J, Gotoh S, Isomura T, Awano H, Suzuki K, Fukuda K, Okada Y, Kiyohara Y, Ooboshi H, Kitazono T; REBIOS Investigators
- Journal Title
  
  J Neurol Sci
  
  Volume: 340 Pages: 75-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] High blood pressure after acute ischemic stroke is associated with poor clinical outcomes: Fukuoka Stroke Registry.2014
- Author(s)
  Ishitsuka K, Kamouchi M, Hata J, Fukuda K, Matsuo R, Kuroda J, Ago T, Kuwashiro T, Sugimori H, Nakane H, Kitazono T; FSR Investigators (Ooboshi H)
- Journal Title
  
  Hypertension
  
  Volume: 63 Issue: 1 Pages: 54-60
- DOI
  10.1161/hypertensionaha.113.02189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] High blood pressure after acute ischemic stroke is associated with poor clinical outcomes : Fukuoka Stroke Registry2014
- Author(s)
  Ishitsuka K, Kamouchi M, Hata J, Fukuda K, Matsuo R, Kuroda J, Ago T, Kuwashiro T, Sugimori H, Nakane H, Kitazono T; FSR Investigators (Ooboshi H)
- Journal Title
  
  Hypertension
  
  Volume: 63 Pages: 54-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Impact of the 1425G/A polymorphism of PRKCH on the recurrence of ischemic stroke: Fukuoka Stroke Registry.2014
- Author(s)
  Matsuo R, Ago T, Hata J, Kuroda J, Wakisaka Y, Sugimori H, Kitazono T, Kamouchi M; FSR Investigators.
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 23 Issue: 6 Pages: 1356-1361
- DOI
  10.1016/j.jstrokecerebrovasdis.2013.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293158, KAKENHI-PROJECT-26461301
[Journal Article] ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and long-term risks of stroke after transient ischemic attack2014
- Author(s)
  Kiyohara T, Kamouchi M, Kumai Y, Ninomiya T, Hata J, Yoshimura S, Ago T, Okada Y, Kitazono T; Fukuoka Stroke Registry Investigators (Ooboshi H)
- Journal Title
  
  Stroke
  
  Volume: 45 Pages: 418-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Plasma S100A12 is associated with functional outcome after ischemic stroke: Research for Biomarkers in Ischemic Stroke.2014
- Author(s)
  Wakisaka Y, Ago T, Kamouchi M, Kuroda J, Matsuo R, Hata J, Gotoh S, Isomura T, Awano H, Suzuki K, Fukuda K, Okada Y, Kiyohara Y, Ooboshi H, Kitazono T; REBIOS Investigators.
- Journal Title
  
  J Neurol Sci
  
  Volume: 340 Issue: 1-2 Pages: 75-9
- DOI
  10.1016/j.jns.2014.02.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262, KAKENHI-PROJECT-26293158, KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-26462163
[Journal Article] Phosphate overload directly induces systemic inflammation and malnutrition as well as vascular calcification in uremia.2014
- Author(s)
  Yamada S, Tokumoto M, Tatsumoto N, Taniguchi M, Noguchi H, Nakano T, Masutani K, Ooboshi H, Tsuruya K, Kitazono T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Phosphate overload directly induces systemic inflammation and malnutrition as well as vascular calcification in uremia2014
- Author(s)
  Yamada S, Tokumoto M, Tatsumoto N, Taniguchi M, Noguchi H, Nakano T, Masutani K, Ooboshi H, Tsuruya K, Kitazono T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] IT network establishment for neuropatients2013
- Author(s)
  Abe K, Uchiyama S, Matsubara E, Muramatsu S, Atsuta N, Kitagawa K, Iguchi Y, Ooboshi H, Kaji R, Terao Y
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 53 Pages: 1155-8
- NAID
  130004505370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] IT network establishment for neuropatients.2013
- Author(s)
  Abe K, Uchiyama S, Matsubara E, Muramatsu S, Atsuta N, Kitagawa K, Iguchi Y, Ooboshi H, Kaji R, Terao Y
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 53 Pages: 1158-8
- NAID
  130004505370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Neuroprotection after cerebral ischemia.2013
- Author(s)
  Namura S, Ooboshi H, Liu J, Yenari MA.
- Journal Title
  
  Ann N Y Acad Sci
  
  Volume: 1278(1) Issue: 1 Pages: 25-32
- DOI
  10.1111/nyas.12087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Neuroprotection after cerebral ischemia2013
- Author(s)
  Namura S, Ooboshi H, Liu J, Yenari MA
- Journal Title
  
  Ann N Y Acad Sci
  
  Volume: 1278 Pages: 25-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Slowly progressive and painless thoracic aortic dissection presenting with a persistent Fever in an elderly patient: the usefulness of combined measurement of biochemical parameters.2013
- Author(s)
  Yamada S, Tokumoto M, Ohkuma T, Kansui Y, Wakisaka Y, Uchizono Y, Tsuruya K, Kitazono T, Ooboshi H.
- Journal Title
  
  Case Rep Med
  
  Volume: 2013 Pages: 498129-498129
- DOI
  10.1155/2013/498129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Novel therapeutic strategies targeting innate immune responses and early inflammation after stroke.2012
- Author(s)
  Shichita T, Ago T, Kamouchi M, Kitazono T, Yoshimura A, Ooboshi H.
- Journal Title
  
  J Neurochem
  
  Volume: 123(S2) Pages: 29-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Risk factors predisposing to stroke recurrence within one year of non-cardioembolic stroke onset : the Fukuoka Stroke Registry2012
- Author(s)
  Kuwashiro T, Sugimori H, Ago T, Kamouchi M, Kitazono T; FSR Investigators (Ooboshi H)
- Journal Title
  
  Cerebrovasc Dis
  
  Volume: 33 Pages: 141-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain2012
- Author(s)
  Shichita T
- Journal Title
  
  Nature Medicine
  
  Volume: 18 Issue: 6 Pages: 911-917
- DOI
  10.1038/nm.2749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590420, KAKENHI-PROJECT-23591262, KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-24117718
[Journal Article] Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain2012
- Author(s)
  Shichita T, Hasegawa E, Kimura A, Morita R, Sakaguchi R, Takada I, Sekiya T, Ooboshi H, Kitazono T, Yanagawa T, Ishii T, Takahashi H, Mori S, Nishibori M, Kuroda K, Akira S, Miyake K, Yoshimura A
- Journal Title
  
  Nat Med
  
  Volume: 18 Pages: 911-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] PDGF receptor ß signaling in pericytes following ischemic brain injury2012
- Author(s)
  Arimura K, Ago T, Kamouchi M, Nakamura K, Ishitsuka K, Kuroda J, Sugimori H, Ooboshi H, Sasaki T, Kitazono T
- Journal Title
  
  Curr Neurovasc Res
  
  Volume: 9 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Novel therapeutic strategies targeting innate immune responses and early inflammation after stroke2012
- Author(s)
  Shichita T, Ago T, Kamouchi M, Kitazono T, Yoshimura A, Ooboshi H
- Journal Title
  
  J Neurochem
  
  Volume: 123S2 Pages: 29-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] PDGF receptor ß signaling in pericytes following ischemic brain injury.2012
- Author(s)
  Arimura K, Ago T, Kamouchi M, Nakamura K, Ishitsuka K, Kuroda J, Sugimori H, Ooboshi H, Sasaki T, Kitazono T
- Journal Title
  
  Curr Neurovasc Res
  
  Volume: 9 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Gene therapy as a novel pharmaceutical intervention for stroke2011
- Author(s)
  Ooboshi H
- Journal Title
  
  Curr Pharm Des
  
  Volume: 17 Pages: 424-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Prestroke glycemic control is associated with the functional outcome in acute ischemic stroke : the Fukuoka Stroke Registry2011
- Author(s)
  Kamouchi M, Matsuki T, Hata J, Kuwashiro T, Ago T, Sambongi Y, Fukushima Y, Sugimori H, Kitazono T; FSR Investigators (Ooboshi H)
- Journal Title
  
  Stroke
  
  Volume: 42 Pages: 2788-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Gene therapy as a novel pharmaceutical intervention for stroke.2011
- Author(s)
  Ooboshi H
- Journal Title
  
  Curr Pharm Des
  
  Volume: 17 Pages: 424-433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591262
[Journal Article] Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes2009
- Author(s)
  Nakamura K, Kamouchi M, Kitazono T, Kuroda J, Shono Y, Hagiwara N, Ago T, Ooboshi H, Ibayashi S, Iida M
- Journal Title
  
  Microvasc Res 77
  
  Pages: 327-34
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Protective effects of angiotensin II Type 1 receptor blocker on cerebral circulation independent of blood pressure2008
- Author(s)
  Kumai Y, Ooboshi H, Ago T, Ishikawa E, Takada J, Kamouchi M, Kitazono T, Ibayashi S, Iida M
- Journal Title
  
  Exp Neurol 210
  
  Pages: 441-448
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Role of NHE1 in calcium signaling and cell proliferation in human CNS pericytes2008
- Author(s)
  Nakamura K, Kamouchi M, Kitazono T, Kuroda J, Matsuo R, Hagiwara N, Ishikawa E, Ooboshi H, Ibayashi S, Iida M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 294
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Role of NHE1 in calcium signaling and cell proliferation inhuman CNS pericytes2008
- Author(s)
  Nakamura K, . . Ooboshi H, et al
- Journal Title
  
  Am J Physiol Heart Circ Physiol 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Protective effects of angiotensin II Type 1 receptor blocker oncerebral circulation independent of blood pressure.2008
- Author(s)
  Kumai Y, Ooboshi H, et al
- Journal Title
  
  Exp Neurol 210
  
  Pages: 441-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Polymorphisms in the lymphotoxin alpha gene and the risk of ischemic stroke in the Japanese population2008
- Author(s)
  Hagiwara N, Kitazono T, Kamouchi M, Kuroda J, Ago T, Hata J, Ninomiya T, Ooboshi H, Kumai Y, Yoshimura S, Tamaki K, Fujii K, Nagao T, Okada Y, Toyoda K, Nakane H, ugimori H, Yamashita Y, Wakugawa Y, Kubo , Tanizaki Y, Kiyohara Y, Ibayashi S, Iida M
- Journal Title
  
  The Fukuoka Stroke Registry and the Hisayama Study 25
  
  Pages: 417-422
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Fukuoka Stroke Registry ; Hisayama study : Polymorphism in the sorbin and SH3-domain-containing-1 (SORBS1) gene and the risk of brain infarction in the Japanese population : the Fukuoka Stroke Registry and the Hisayama study2008
- Author(s)
  Hagiwara N, Kitazono T, Kamouchi M, Kuroda J, Ago T, Hata J, Ninomiya T, Ooboshi H, Kumai Y, Yoshimura S, Tamaki K, Fujii K, Nagao T, Okada Y, Toyoda K, Nakane H, Sugimori H, Yamashita Y, Wakugawa Y, Kubo M, Tanizaki Y, Kiyohara Y, Ibayashi S, Iida M
- Journal Title
  
  Eur J Neurol 15
  
  Pages: 481-486
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Postischemic gene transfer of soluble Flt-1 protects against brain ischemia with marked attenuation of blood-brain barrier permeability2007
- Author(s)
  Kumai Y, Ooboshi H, et. al.
- Journal Title
  
  J Cereb Blood Flow Metab 27
  
  Pages: 1152-1160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Hydrogen peroxide-induced Ca(2+) responses in CNS pericytes2007
- Author(s)
  Kamouchi M, Kitazono T, Ago T, Wakisaka M, Kuroda J, Nakamura K, Hagiwara N, Ooboshi H, Ibayashi S, Iida M
- Journal Title
  
  Neurosci Lett 416
  
  Pages: 12-16
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Postischemic gene transfer of soluble Flt-1 protects against brain ischemia with marked attenuation of blood-brain barrier permeability2007
- Author(s)
  Kumai Y, Ooboshi H, Ibayashi S, Ishikawa E, Sugimori H, Kamouchi M, Kitazono T,Egashira K, Iida M
- Journal Title
  
  J Cereb Blood Flow Metab 27
  
  Pages: 1152-1160
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] NAD(P)H oxidase p22phox C242T polymorphism and ischemic stroke in Japan : the Fukuoka Stroke Registry and the Hisayama study2007
- Author(s)
  Kuroda J, Kitazono T, Ago T, Ninomiya T, Ooboshi H, Kamouchi M, Kumai Y, Hagiwara N, Yoshimura S, Tamaki K, Kusuda K, Fujii K, Nagao T, Okada Y, Toyoda K, Nakane H, Sugimori H, Yamashita Y, Wakugawa Y, Asano K, Tanizaki Y, Kiyohara Y, Ibayashi S, Iida M
- Journal Title
  
  Eur J Neurol 14
  
  Pages: 1091-1097
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Role of substantia innominata in cerebral blood flow autoregulation2007
- Author(s)
  Ota K, Kitazono T, Ooboshi H, Kamouchi M, Katafuchi T, Aou S, Yamashita Y, Ibayashi S, Iida M
- Journal Title
  
  Brain Res 1135
  
  Pages: 146-153
- Data Source
  KAKENHI-PROJECT-19590993
[Journal Article] Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger2007
- Author(s)
  Ifuku M, Farber K, Okuno Y, Yamakawa Y, Miyamoto T, Nolte C, Merrino VF, Kita S, Iwamoto T, Komuro I, Wang B, Cheung G, Ishikawa E, Ooboshi H, Bader M, Wada K, Kettenmann H, Noda M
- Journal Title
  
  J Neurosci 27
  
  Pages: 13065-13073
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] 介護老人保健施設における肺炎患者の嚥下造影検査の解析2018
- Author(s)
  山野貴史, 梅野悠太, 杉野真理子, 鵜木あゆみ, 内藤徹, 中島與志行, 大星博明
- Organizer
  第41回日本嚥下医学会
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] 長期的血圧変動に及ぼす睡眠時無呼吸症候群の影響：職域集団における検討2017
- Author(s)
  寒水康雄, 松村潔, 守永友希, 井上美奈子, 坂田智子, 大石絵美, 後藤健一, 福原正代, 大坪俊夫, 大星博明, 北園孝成
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR12017
- Author(s)
  Shichita T, Ooboshi H, Takahashi S, Kodama T, Yoshimura A
- Organizer
  第28回国際脳循環代謝学会 Brain 2017
- Place of Presentation
  Berlin, Germany
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] 経口吸着剤AST-120の腎機能に及ぼす影響：無作為化試験のメタ解析2017
- Author(s)
  田中茂, 二宮利治, 徳本正憲, 大星博明, 鶴屋和彦, 北園孝成
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] 血液透析患者における尿素窒素・クレアチニン比と死亡、合併症罹患の関連：Qコホート研究2017
- Author(s)
  田中茂, 二宮利治, 谷口正智, 徳本正憲, 大星博明, 鶴屋和彦, 北園孝成
- Organizer
  第62回日本透析医学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR12017
- Author(s)
  Shichita T, Ooboshi H, Yoshimura A
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] Usefulness of bright arterial appearance in ASL MR perfusion image2017
- Author(s)
  Kanazawa Y, Arakawa S, Morioka T, Ago T, Kitazono T, Ooboshi H
- Organizer
  第28回国際脳循環代謝学会 Brain 2017
- Place of Presentation
  Berlin, Germany
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] IgA腎症患者における血尿と末期腎不全発症リスク2017
- Author(s)
  田中茂, 片渕律子, 徳本正憲, 土本晃裕, 大星博明, 鶴屋和彦, 北園孝成
- Organizer
  第47回日本腎臓学会東部学術大会
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] A pivotal role of peroxiredoxin in the evolution of brain infarction2016
- Author(s)
  Hiroaki Ooboshi
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Venice, Italy
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] A pivotal role of peroxiredoxin in the evolution of brain infarction.2016
- Author(s)
  Ooboshi H, Shichita T, Yoshimura A
- Organizer
  25th European Stroke Conference
- Place of Presentation
  ベネチア、イタリア
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] Neurovascular protectionによる創薬研究2016
- Author(s)
  大星博明
- Organizer
  第57回日本神経学会総会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] The protective effects of caloric restriction on phosphate-induced calcification via the upregulation of SIRT1 in human vascular smooth muscle cells2016
- Author(s)
  Tokumoto M, Yamada S, Tsuruya K, Kitazono T, Ooboshi H
- Organizer
  2016年アメリカ腎臓病学会
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] The precedence of the reduced osteopontin expression and the increased calcium phosphate nanoparticle to the calcification by phosphate load with normal fasting glucose level in human vascular smooth muscle cells.2015
- Author(s)
  Tokumoto M, Yamada S, Tsuruya K, Kitazono T, Ooboshi H
- Organizer
  アメリカ腎臓病学会2015
- Place of Presentation
  サンジエゴ、米国
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] Comparative effectiveness of oral and injectable vitamin d receptor activator on infectious mortality in hemodialysis patients: the Q Cohort Study.2015
- Author(s)
  Tanaka S, Ninomiya T, Taniguchi M, Tokumoto M, Hirakata H, Ooboshi H, Tsuruya K, and Kitazono T
- Organizer
  アメリカ腎臓病学会2015
- Place of Presentation
  サンジエゴ、米国
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] Neurovascular unitを守る治療研究最前線－主に免疫細胞の立場から2015
- Author(s)
  大星博明
- Organizer
  第56回日本神経学会総会
- Place of Presentation
  新潟朱鷺メッセ
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] 脳梗塞の病態と新規治療開発の将来像－自然免疫を標的とした脳梗塞治療2015
- Author(s)
  大星博明
- Organizer
  第27回日本脳循環代謝学会
- Place of Presentation
  富山市国際会議場
- Year and Date
  2015-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] Innate immune response as a novel therapeutic target of brain infarction.2014
- Author(s)
  Hiroaki Ooboshi
- Organizer
  International Symposium on Mechanisms of Innate immune Immunity, Cell Death and Inflammation
- Place of Presentation
  ゲント、ベルギー
- Year and Date
  2014-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] Basic fibroblast growth factor after ischemic stroke in diabetic patients - Research for Biomarkers in Ischemic Stroke (REBIOS) -.2014
- Author(s)
  Nakamura K, Ago T, Arimura K, Makihara N, Nishimura A, Matsuo R, Kuroda J, Wakisaka Y, Isomura T, Awano H, Suzuki K, Okada Y, Kamouchi M, Kiyohara Y, Ooboshi H, Kitazono T
- Organizer
  International Stroke Conference 2014
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Differential effects of dietary phosphate restriction and protein restriction on malnutrition, inflammation and vascular calcification in uremic rats2014
- Author(s)
  Yamada S, Tokumoto M, Tatsumoto N, Ooboshi H, Tsuruya K, and Kitazono T
- Organizer
  2014年アメリカ腎臓病学会
- Place of Presentation
  フィラデルフィア、米国
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] DAMPsによる脳梗塞後の炎症とその終焉2014
- Author(s)
  七田崇、大星博明、吉村昭彦
- Organizer
  第26回日本脳循環代謝学会
- Place of Presentation
  岡山
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] The etidronate disodium hydrate directly inhibits both initiation and progression of phosphate-induced calcification in human vascular smooth muscle cells.2014
- Author(s)
  Tokumoto M, Yamada S, Fujino T, Tsuruya K, Kitazono T, Ooboshi H
- Organizer
  2014年アメリカ腎臓病学会
- Place of Presentation
  フィラデルフィア、米国
- Year and Date
  2014-11-14
- Data Source
  KAKENHI-PROJECT-26461301
[Presentation] Basic fibroblast growth factor after ischemic stroke in diabetic patients - Research for Biomarkers in Ischemic Stroke (REBIOS) -2014
- Author(s)
  Nakamura K, Ago T, Arimura K, Makihara N, Nishimura A, Matsuo R, Kuroda J, Wakisaka Y, Isomura T, Awano H, Suzuki K, Okada Y, Kamouchi M, Kiyohara Y, Ooboshi H, Kitazono T
- Organizer
  International Stroke Conference 2014
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-02-12
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] 脳梗塞発症後の糖尿病患者におけるbasic FGFの上昇: Research for Biomarkers in Ischemic Stroke (REBIOS)2013
- Author(s)
  中村晋之、吾郷哲朗、有村公一、牧原典子、粟野秀人、鈴木一夫、清原裕、鴨打正浩、大星博明、北園孝成
- Organizer
  日本脳循環代謝学会総会
- Place of Presentation
  札幌
- Year and Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Phosphate overload induces systemic inflammation, malnutrition, and vascular calcification in uremia2013
- Author(s)
  Yamada S, Tokumoto M, Taniguchi M, Tsuruya K, Ooboshi H, and Kitazono T
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta, USA
- Year and Date
  2013-11-08
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] 脳梗塞後のS100A12血漿濃度は昨日予後不良と挿管する：Research for Biomarkers in Ischemic Stroke2013
- Author(s)
  脇坂義信, 吾郷哲朗, 鴨打正浩, 磯村哲, 粟野秀人, 鈴木一夫, 岡田靖, 清原裕, 大星博明, 北園孝成
- Organizer
  第38回日本脳卒中学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] The combined therapy with calcitriol and a calcimimetic agent, R568, ameliorates phosphorus-induced calcification with altered expression of SIRT1 and ALP in human vascular smooth muscle cells.2013
- Author(s)
  Tokumoto M, Yamada S, Fujino T, Tsuruya K, Kitazono T, Ooboshi H
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] The expression of pericyte PDGFRβis regulated by basic FGF after ischemic stroke - Research for Biomarkers in Ischemic Stroke (REBIOS) -2013
- Author(s)
  Nakamura K, Arimura K, Ago T, Makihara N, Isomura T, Watabe W, Awano H, Suzuki K, Kamouchi M, Kiyohara Y, Ooboshi H, Kitazono T
- Organizer
  Neuroscience Meeting 2013
- Place of Presentation
  San Diego, USA
- Year and Date
  2013-11-09
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] 脳梗塞後のS100A12血漿濃度は昨日予後不良と挿管する:Research for Biomarkers in Ischemic Stroke2013
- Author(s)
  脇坂義信,吾郷哲朗,鴨打正浩,磯村哲,粟野秀人,鈴木一夫,岡田靖,清原裕,大星博明,北園孝成
- Organizer
  第38回日本脳卒中学会総会
- Place of Presentation
  東京
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] The expression of pericyte PDGFRβ is regulated by basic FGF after ischemic stroke - Research for Biomarkers in Ischemic Stroke (REBIOS) -.2013
- Author(s)
  Nakamura K, Arimura K, Ago T, Makihara N, Isomura T, Watabe W, Awano H, Suzuki K, Kamouchi M, Kiyohara Y, Ooboshi H, Kitazono T
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Extracellular newly identified receptor for advanced glycation endproducts binding protein (EN-RAGE) predicts the outcome in patients with acute ischemic stroke : Research for Biomarkers in Ischemic Stroke2013
- Author(s)
  Wakisaka Y, Ago T, Kamouchi M, Kuroda J, Matsuo R, Gotoh S, Watanabe W, Isomura T, Awano H, Suzuki K, Fukuda K, Okada Y, Kiyohara Y, Ooboshi H, Kitazono T
- Organizer
  International Stroke Conference 2013
- Place of Presentation
  Honolulu, USA
- Year and Date
  2013-02-06
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] The combined therapy with calcitriol and a calcimimetic agent, R568, ameliorates phosphorus-induced calcification with altered expression of SIRT1 and ALP in human vascular smooth muscle cells2013
- Author(s)
  Tokumoto M, Yamada S, Fujino T, Tsuruya K, Kitazono T, Ooboshi H
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta, USA
- Year and Date
  2013-11-08
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Extracellular newly identified receptor for advanced glycation endproducts binding protein (EN-RAGE) predicts the outcome in patients with acute ischemic stroke: Research for Biomarkers in Ischemic Stroke2013
- Author(s)
  Wakisaka Y, Ago T, Kamouchi M, Kuroda J, Matsuo R, Gotoh S, Watanabe W, Isomura T, Awano H, Suzuki K, Fukuda K, Okada Y, Kiyohara Y, Ooboshi H, Takanari K
- Organizer
  Stroke 2013
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Phosphate overload induces systemic inflammation, malnutrition, and vascular calcification in uremia.2013
- Author(s)
  Yamada S, Tokumoto M, Taniguchi M, Tsuruya K, Ooboshi H, and Kitazono T
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Innate immunity as a novel therapeutic target of brain infarction2012
- Author(s)
  Hiroaki Ooboshi
- Organizer
  Transpacific Workshop o Stroke
- Place of Presentation
  New Orleans, USA
- Year and Date
  2012-10-18
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Immune response as a novel therapeutic target of brain infarction2012
- Author(s)
  大星博明
- Organizer
  第44回日本動脈硬化学会
- Place of Presentation
  福岡
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Immune response as a novel therapeutic target of brain infarction.2012
- Author(s)
  大星博明
- Organizer
  第44回日本動脈硬化学会総会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Innate immunity as a novel therapeutic target of brain infarction.2012
- Author(s)
  Hiroaki Ooboshi
- Organizer
  Transpacific Workshop o Stroke
- Place of Presentation
  New Orleans
- Invited
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] IL-23 production from infiltrating macrophage in the ischemic brain is dependent on TLR signaling pathway2011
- Author(s)
  Shichita T, Ooboshi H, Takada I, Ishii T, Kuroda K, Miyake K, Yoshimura A
- Organizer
  XXVth International Symposium on Cerebral Blood Flow and Metabolism (Brain 2011)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] IL-23 production from infiltrating macrophage in the ischemic brain is dependent on TLR signaling pathway.2011
- Author(s)
  Shichita T, Ooboshi H, Takada I, Ishii T, Kuroda K, Miyake K, Yoshimura A
- Organizer
  第25回国際脳循環代謝学会
- Place of Presentation
  スペイン、Barcelona
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Innate immune response as a novel therapeutic target of brain infarction2011
- Author(s)
  Ooboshi H
- Organizer
  First Turkish International Stroke Meeting
- Place of Presentation
  Antalya, Turkey
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] T細胞と脳虚血後炎症2011
- Author(s)
  七田崇、大星博明、北園孝成、石井哲郎、黒田和道、三宅健介、審良静男、吉村昭彦
- Organizer
  第23回日本脳循環代謝学会
- Place of Presentation
  東京
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] T細胞と脳虚血後炎症2011
- Author(s)
  七田崇、大星博明、北園孝成、石井哲郎、黒田和道、三宅健介、審良静男、吉村昭彦
- Organizer
  第23回日本脳循環代謝学会(招待講演)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Innate immune response as a novel therapeutic target of brain infarction.2011
- Author(s)
  Ooboshi H
- Organizer
  The First International Turkish Stroke Meeting(招待講演)
- Place of Presentation
  トルコ共和国、Antalya
- Data Source
  KAKENHI-PROJECT-23591262
[Presentation] Neurovascular Protection を目指した遺伝子治療2009
- Author(s)
  大星博明
- Organizer
  <シンポジウム脳卒中の先端治療研究-臨床への道->第32回日本脳卒中学会総会
- Place of Presentation
  島根
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] 脳虚血後のテルミサルタン投与は降圧作用を介さずに出血性梗塞を抑制する2008
- Author(s)
  石川英一, 大星博明, 熊井康敬, 中村晋之,萩原のり子, 黒田淳哉, 鴨打正浩, 北園孝成,井林雪郎, 飯田三雄
- Organizer
  第33回日本脳卒中学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-20
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] Neuroprotection and neurogenesis by post-ischemic gene transferof midkine.2008
- Author(s)
  Ooboshi H, et al
- Organizer
  6^<th> World Stroke Congress
- Place of Presentation
  Vienna, Austria
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] 脳梗塞に対する遺伝子治療の展望2008
- Author(s)
  大星博明
- Organizer
  <シンポジウム脳虚血における脳保護・再生>第20会日本脳循環代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] Neuroprotection and neurogenesis by post-ischemic gene transfer of midkine2008
- Author(s)
  Ooboshi H, Ishikawa E, Kumai Y, Takada J, Nakamura K, Sugimori H, Kamouchi M, Kitazono T, Ibayashi S, Iida M
- Organizer
  6^<th> World Stroke Conference
- Place of Presentation
  Vienna, Austria
- Year and Date
  2008-09-26
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] Potential augmentation of neurogenesis by post-ischemic gene transfer of midkine2008
- Author(s)
  Ishikawa E, Ooboshi H, et. al.
- Organizer
  International Stroke Conference 2008
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2008-02-20
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] Neuroprotective role of CCB up-to-date2007
- Author(s)
  Ooboshi H
- Organizer
  International Symposium on Cerebral Blood Flow and Metabolism
- Place of Presentation
  Osaka
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] Augmentation of neurogenesis by post-ischemic gene transfer of midkine2007
- Author(s)
  Ishikawa E, Ooboshi H, Kumai Y, Takada J, Ibayashi S, Iida M
- Organizer
  CSHL Conference In Vivo Barrier to Gene Delivery
- Place of Presentation
  Cold Spring Harbor
- Data Source
  KAKENHI-PROJECT-19590993
[Presentation] Neurovascular protection of brain infarction by postischemic gene transfer2007
- Author(s)
  Ooboshi H, Ishikawa E, Kumai Y, Takada J, Sugimori H, Kamouchi M, Kitazono T, Ibayashi S, Iida M
- Organizer
  2nd Meeting of Asian Stroke Forum
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19590993

1. KAMOUCHI Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. KITAZONO Takanari

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. KURODA Junya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. AGO Tetsuro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. NISHIMURA Ataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. TACHIBANA Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. MASUTANI Kosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 甲斐久史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 福田賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 福田治久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 松尾龍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 七田崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 鶴屋和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OOBOSHI Hiroaki 大星 博明

Research Projects

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Co-Researchers

Research on therapy for brain infarction targeting innate immunityPrincipal Investigator

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Targeting inflammation-immune response as a novel strategy for the treatment of brain infarctionPrincipal Investigator

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Gene therapy with Sendai virus vector ta rgeting for microcirculatory construct in brain infarctionPrincipal Investigator

Principal Investigator

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Gene therapy against ischemic stroke targeting inflammatory signalsPrincipal Investigator

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[Book] 脳卒中病態学のススメ2018

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[Book] Acute brain impairment2017

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[Book] DAMPs (damage-associated molecular patterns)と炎症. 脳卒中 -新時代の治療を求めて-2016

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[Book] 無症候性脳出血とmicrobleeds.脳血管障害の治療最前線2014

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[Book] 脳出血慢性期の治療. 最最新臨床脳卒中学(下)2014

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[Book] 虚血による神経障害のメカニズム-脳梗塞と炎症. 最新臨床脳卒中学(上)2014

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[Book] 無症候性脳出血とmicrobleeds. 脳血管障害治療最前線2014

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[Book] Midkine gene transfer in brain infarction. Chap 13, Midkine : From Embryogenesis to Pathogenesis and Therapy2012

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[Book] Midkine gene transfer in brain infarction. Ch 13, Midkine: From Embryogenesis to Pathogenesis and Therapy2012

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[Book] Midkine: From Embryogenesis to Pathogenesis and Therapy, in press Springer Science2012

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[Book] Potentilas of gene therapy for neuroprotection and neurogenesis inbrain ischemia. In Recent Advances in Neurogenesis, Neuroproregeneration and Neuroprotection2009

Author(s)

OOBOSHI Hiroaki 大星博明