Saika Takashi 雑賀隆史

… Alternative Names

SAIKA TAKASHI 雑賀隆史

SAIKA Takashi 雑賀隆史

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Researcher Number	10314676
Other IDs	https://orcid.org/0000-0002-1770-5758
Affiliation (Current)	2024: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 愛媛大学, 医学系研究科, 教授 2009 – 2010: Okayama University, 大学院・医歯薬学総合研究科, 准教授 2008: 岡山大学, 医学部・歯学部付属病院, 講師 2004 – 2008: 岡山大学, 医学部・歯学部附属病院, 講師 2005: 岡山大学, 医学部・歯学部附属病院, 助手
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Urology / Basic Section 90130:Medical systems-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 前立腺癌 / 骨転移 / インターロイキン12 / 遺伝子治療 / 制御因子 / アンドロゲン受容体 / サルコペニア / アンドロゲン / C2C12 / Akt … More / 骨格筋 / 上皮成長因子受容体 / androgen receptor / androgen / データベース / 分子機構 / 転移制御 / 前立腺がん / Prostate Cancer / Interleukin-12 / cancer immunology / Gene therapy / Dendritic cell / 抗腫瘍免疫 / 樹状細胞 / IL-12 / 非ウイルスベクター / 高密度焦点超音波(HIFU) / 遺伝子導入 / 高密度焦点超音波 … More Except Principal Investigator 前立腺癌 / PSMA / REIC / シングルセル解析 / 水腎症 / 腎盂内圧測定 / 質量分析法 / 腫瘍学 / 遺伝子治療 / FAT4 / 新規治療標的 / CDH11 / 転移性膀胱癌 / 数値流体計算 / スフェロイド / 導管内浸潤前立腺癌 / 遺伝子解析 / 神経内分泌分化 / IDCP / 空間的遺伝子発現解析 / 神経内分泌前立腺癌 / 導管癌 / 神経内分泌癌 / 腎癌 / 腎がん / ガイド波 / 腎盂内圧 / 反射波 / 生体膜 / 血管内皮細胞 / Cullin3型ユビキチンリガーゼ / CUL3 / prostate cancer specimen / tube formation / LNCaP / HUVECs / tumor endothelial cells / AlphaScreen法 / SPOP / ユビキチンリガーゼ / 前立腺がん / ノックアウトマウス / 蛋白治療. / サイトカイン / REIK/DKK-3 / 樹状細胞 / 抗癌免疫 / 腎細胞癌 / REIC/Dkk-3 / HSP70 / Dkk-3 / Dkk3 / P-glycoprotein / DKK3 / JNK / ストレス応答分子 / 薬剤耐性 / 遺伝子治療学 / 遺伝子導入 / 生分解性ポリマー / 生分解 / テーラーメイド / ポリマー Less

前立腺癌骨転移の分子メカニズム解明と革新的治療法開発への基盤的研究Principal Investigator
- Principal Investigator
  
  雑賀隆史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
前立腺癌スフェロイドのシングルセル解析による導管内浸潤前立腺癌の病態解明
- Principal Investigator
  
  三浦徳宣
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
数値流体計算を用いた腎盂内圧力変化の解析と腎盂内圧が腎機能へ与える影響
- Principal Investigator
  
  西村謙一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Ehime University
ビッグデータ解析を用いた転移性膀胱癌に対する新規治療標的分子の探索
- Principal Investigator
  
  新井欧介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
腎癌関連血管内皮細胞におけるPSMAの発現制御機構及び、その分子機能の解明
- Principal Investigator
  
  菊川忠彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
International collaboration research on the identification of novel driver genes for prostate cancer by single cell analysis.
- Principal Investigator
  
  菊川忠彦
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Ehime University
シングルセル解析による腫瘍微小環境を介した前立腺神経内分泌腫瘍発生機序の解明
- Principal Investigator
  
  渡辺隆太
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
fundamental study for indirect regulattions of skeletal muscle mass by androgen-like action outside of skeletal muscle fibersPrincipal Investigator
- Principal Investigator
  
  Saika Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
Regulatory mechanisms of PSMA expression and its molecular functions in prostate cancer-associated vascular endothelial cells.
- Principal Investigator
  
  Miura Noriyoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
Development of a new non-invasive intra-renal pelvis pressure measurement based on non-destructive engineering techniques.
- Principal Investigator
  
  Nishimura Kenichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Ehime University
Analysis of the molecular mechanism of PSMA in prostate cancer cells
- Principal Investigator
  
  Miura Noriyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
exploring innovative therapeutic target for bone metastatic prostate cancer based on analysis of molecular mechanism.Principal Investigator
- Principal Investigator
  
  SAIKA TAKASHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
The identification of CUL3-SPOP and CUL3-PLZF target substrates for therapeutic targets in prostate cancer cells
- Principal Investigator
  
  Kikugawa Tadahiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Ehime University
Basic and developmental research of a novel anti-tumor protein with dendritic cell-inducible activity.
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Novel approach with sonoporation in IL12 gene therapy for prostate cancer.Principal Investigator
- Principal Investigator
  
  SAIKA Takashi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Fundamental research for new molecular mechanism of anticancer resistance in urogenital cancer
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
生分解性ポリマーを用いたテーラーメイド型遺伝子治療用ベクターの開発研究
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Okayama University
Development of cell and gene therapy for prostate cancer with dendritic cells engineered to produce interleukin-12Principal Investigator
- Principal Investigator
  
  SAIKA Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University

[Journal Article] 神経内分泌前立腺癌のシングルセル解析と農学分野への応用の可能性2024
- Author(s)
  渡辺隆太、雑賀隆史
- Journal Title
  
  アグリバイオ
  
  Volume: 8 (2) Pages: 173-177
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] Spatial Gene Expression Analysis Reveals Characteristic Gene Expression Patterns of De Novo Neuroendocrine Prostate Cancer Coexisting with Androgen Receptor Pathway Prostate Cancer2023
- Author(s)
  Watanabe Ryuta、Miura Noriyoshi、Kurata Mie、Kitazawa Riko、Kikugawa Tadahiko、Saika Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 10 Pages: 8955-8955
- DOI
  10.3390/ijms24108955
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449, KAKENHI-PROJECT-21K09373
[Journal Article] シングルセル解析による前立腺癌神経内分泌分化機序解明2023
- Author(s)
  渡辺隆太、雑賀隆史
- Journal Title
  
  細胞
  
  Volume: 55 (7) Pages: 389-391
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] Senescent <scp>CD8</scp> <sup>+</sup> T cells acquire <scp>NK</scp> cell‐like innate functions to promote antitumor immunity2023
- Author(s)
  Kakuda Toshio、Suzuki Junpei、Matsuoka Yuko、Kikugawa Tadahiko、Saika Takashi、Yamashita Masakatsu
- Journal Title
  
  Cancer Science
  
  Volume: x Issue: 7 Pages: 2810-2820
- DOI
  10.1111/cas.15824
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03504, KAKENHI-PROJECT-21K09373
[Journal Article] IDCP症例における遺伝子異常の解析2023
- Author(s)
  渡辺隆太、塩出涼、鈴木大一郎、信森祥太、杉原直哉、山川真季、佐伯佳央里、河野玲奈、新井欧介、大西智也、角田俊雄、野田輝乙、西村謙一、福本哲也、三浦徳宣、倉田美恵、宮内勇貴、北澤理子、Michael C Haffner、菊川忠彦、雑賀隆史
- Journal Title
  
  泌尿器外科
  
  Volume: 36(8) Pages: 939-941
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] 神経内分泌前立腺癌の理解を目指したシングルセル解析の応用2023
- Author(s)
  渡辺隆太、雑賀隆史
- Journal Title
  
  38 (14)
  
  Volume: 38 (14) Pages: 1238-1241
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] Uhrf1 governs the proliferation and differentiation of muscle satellite cells.2022
- Author(s)
  Sakai H, Sawada Y, Tokunaga N, Tanaka K, Nakagawa S, Sakakibara I, Ono Y, Fukada SI, Ohkawa Y, Kikugawa T, Saika T, Imai Y.
- Journal Title
  
  iScience.
  
  Volume: 25 Issue: 3 Pages: 103928-103928
- DOI
  10.1016/j.isci.2022.103928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-21H00232, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03786, KAKENHI-PROJECT-21K09373, KAKENHI-PROJECT-21K17568, KAKENHI-PROJECT-23K24462
[Journal Article] CD21lo B Cells Could Be a Potential Predictor of Immune-Related Adverse Events in Renal Cell Carcinoma.2022
- Author(s)
  Nishimura K, Konishi T, Ochi T, Watanabe R, Noda T, Fukumoto T, Miura N, Miyauchi Y, Kikugawa T, Takenaka K, Saika T.
- Journal Title
  
  J Pers Med.
  
  Volume: 12 Issue: 6 Pages: 888-894
- DOI
  10.3390/jpm12060888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09373, KAKENHI-PROJECT-21H02949
[Journal Article] PSMA‐positive membranes secreted from prostate cancer cells have potency to transform vascular endothelial cells into an angiogenic state2021
- Author(s)
  Watanabe Ryuta、Maekawa Masashi、Kiyoi Takeshi、Kurata Mie、Miura Noriyoshi、Kikugawa Tadahiko、Higashiyama Shigeki、Saika Takashi
- Journal Title
  
  The Prostate
  
  Volume: 81 Issue: 16 Pages: 1390-1401
- DOI
  10.1002/pros.24237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09427
[Journal Article] GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer2020
- Author(s)
  Sawada Y, Kikugawa T, Iio H, Sakakibara I, Yoshida S, Ikedo A, Yanagihara Y, Saeki N, Gyorffy B, Kishida T, Okubo Y, Nakamura Y, Miyagi Y, Saika T, Imai Y.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 146 Issue: 5 Pages: 1369-1382
- DOI
  10.1002/ijc.32554
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09168, KAKENHI-PROJECT-19K16015, KAKENHI-PROJECT-19H03786, KAKENHI-PROJECT-16H06277
[Journal Article] SPOP is essential for DNA-protein crosslink repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.2020
- Author(s)
  Watanabe R, Maekawa M, Hieda M, Taguchi T, Miura N, Kikugawa T, Saika T, Higashiyama S.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 31 Issue: 6 Pages: 478-490
- DOI
  10.1091/mbc.e19-08-0456
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06226, KAKENHI-PROJECT-19K18613, KAKENHI-PROJECT-18K09137
[Journal Article] SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.2020
- Author(s)
  Watanabe R, Kikugawa T, Saika T, Higashiyama S, et al.
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 31 Issue: 8 Pages: 478-490
- DOI
  10.1091/mbc.
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11142
[Journal Article] Laparoscopic management of complicated urachal remnants in adults2012
- Author(s)
  Araki M, Saika T, Araki D, Kobayashi Y, Uehara S, Watanabe T, Yamada K, Nasu Y, Kumon H
- Journal Title
  
  World J Urol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Implications of transcriptional factor, OCT-4, in human bladder malignancy and tumor recurrence.2011
- Author(s)
  Huang P, Chen J, Wang L, Na Y, Kaku H, Ueki H, Sasaki K, Yamaguchi K, Zhang K, Saika T, Nasu Y, Watanabe M, Kumon H
- Journal Title
  
  Med Oncol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Preoperative positive urine cytology is a risk factor for subsequent development of bladder cancer after nephroureterectomy in patients with upper urinary tract urothelial carcinoma.2011
- Author(s)
  Kobayashi Y, Saika T, Miyaji Y, Saegusa M, Arata R, Akebi N, Takenaka T, Manabe D, Nasu Y, Kumon H.
- Journal Title
  
  World J Urol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Could salvage surgery after chemotherapy have clinical impact on cancer survival of patients with metastatic urothelial carcinoma?2011
- Author(s)
  Bekku K, Saika T, Kobayashi Y, Kioshimoto R, Kanbara T, Nasu Y, Kumon H.
- Journal Title
  
  Int J Clin Oncol.
- NAID
  10031176243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Potent antitumor effects of combined therapy with a telomerase-specific2010
- Author(s)
  Huang P, Kaku H, Chen J, Kashiwakura Y, Saika T, Nasu Y, Urata Y, Fujiwara T, Watanabe M, Kumon H
- Journal Title
  
  replication-competent adenovirus (OBP-301) and IL-2 in a mouse model of renal cell carcinoma. Cancer Gene Ther
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus(OBP-301) and IL-2 in a mouse model of renal cell carcinoma.2010
- Author(s)
  Huang P, Kaku H, Chen J, Kashiwakura Y, Saika T, Nasu Y, Urata Y, Fujiwara T, Watanabe M, Kumon H.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: 17(7) Pages: 484-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441
[Journal Article] Prospective longitudinal comparative study of health-related quality of life in patients treated with radical prostatectomy or permanent brachytherapy for prostate cancer.2009
- Author(s)
  Kobuke M, Saika T, Nakanishi Y, Ebara S, Manabe D, Uesugi T, Nose H, Arata R, Tsushima T, Nasu Y, Kumon H
- Journal Title
  
  Acta Med Okayama 63(3)
  
  Pages: 129-35
- NAID
  120002313130
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] A comparison of proteomic profiles changes during 17beta-estradiol treatment in human prostate cancer PC-3 cell line.2009
- Author(s)
  Chen J, Huang P, Kaku H, Zhang K, Watanabe M, Saika T, Nasu Y, Kumon H
- Journal Title
  
  Cancer Genomics Proteomics 6
  
  Pages: 331-5
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Iodine-125 seed impla(permanent brachytherapy) for clinically localized prostate cancer.2008
- Author(s)
  Ebara S, Katayama N, Tanimoto R, Edamura K, Nose H, Manabe D, Kobayashi T, Kobayashi Y, Kobuke M, Takemoto M, Saika T, Nasu Y, Kanazawa S, Kumon H
- Journal Title
  
  Acta Med Okayama 62(1)
  
  Pages: 9-13
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Identification of the HERV-K gag antigen in prostate cancer by SEREX using autologous patient serum and its immunogenicity.2008
- Author(s)
  Ishida T, Obata Y, Ohara N, Matsushita H, Sato S, Uenaka A, Saika T, Miyamura T, Chayama K, Nakamura Y, Wada H, Yamashita T, Morishima T, Old LJ, Nakayama E
- Journal Title
  
  Cancer Immun 8
  
  Pages: 15-15
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model.2008
- Author(s)
  Huang P, Watanabe M, Kaku H, Kashiwakura Y, Chen J, Saika T, Nasu Y, Fujiwara T, Urata Y, Kumon H
- Journal Title
  
  Cancer Gene Ther 15(5)
  
  Pages: 315-22
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Initial report of hybrid radical prostatectomy for prostate cancer: reduced bleeding, clear vision, and secure surgical margins.2008
- Author(s)
  Saika T, Kobayashi Y, Watanabe T, Manabe D, Ebara S, Uehara S, Nasu Y, Kumon H
- Journal Title
  
  Acta Med Okayama 62(6)
  
  Pages: 379-84
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] N-h.Mechanistic Analysis of Resistance to REIC/Dkk-3-induced Apoptosis in Human Bladder Cancer Cells2008
- Author(s)
  Kobayashi, T., Sakaguchi M., Tanimoto R., Abarzua, F., Takaishi M., Kaku, H. Kataoka, , K., Saika T.,Nasu Y., Miyazaki M., Kumon H., Huh
- Journal Title
  
  Acta Med Okayama 62
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model2007
- Author(s)
  Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh N.H, Kumon H
- Journal Title
  
  Cancer Gene Ther 14
  
  Pages: 765-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17659505
[Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model2007
- Author(s)
  Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh N.H. Kumon H
- Journal Title
  
  Cancer Gene Ther 14
  
  Pages: 765-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-32007
- Author(s)
  Abarzua F, Sakaguchi M, Tanimoto R, Sonegawa H, Li DW, Edamura K, Kobayashi T, Watanabe M, Kashiwakura Y, Kaku H, Saika T, Nakamura K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Mol Med. 20
  
  Pages: 37-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy.2007
- Author(s)
  Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson TC, Kumon H
- Journal Title
  
  Mol Ther 15(4)
  
  Pages: 834-40
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy2007
- Author(s)
  Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson T.C, Kumon H
- Journal Title
  
  Mol Ther 15
  
  Pages: 834-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Suicide gene therapy with adenoviral vector delivery of HSV-tk gene and the intravnous administration of ganciclovir for patients with local recurrence of prostate cancer after hormonal therapy2007
- Author(s)
  Nasu Y, Saika T et al.
- Journal Title
  
  Molecular Therapy (In press)
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] 岡山大学における前立腺癌遺伝子治療研究の現況と展望 -ベーシックリサーチからトランスレーショナルリサーチへ-2007
- Author(s)
  賀来春紀, 藤原俊義, 渡部昌実, 黄鵬, 陳潔, 谷本竜太フェルナンドアバルスア, 枝村康平真鍋大輔, 江原伸, 雑賀隆史那須保友, 公文裕巳
- Journal Title
  
  西日本泌尿器科 69
  
  Pages: 221-229
- NAID
  10019994587
- Data Source
  KAKENHI-PROJECT-17659505
[Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model.2007
- Author(s)
  Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh NH, Kumon H
- Journal Title
  
  Cancer Gene Ther 14(9)
  
  Pages: 765-72
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumo growth and metastasis in an orthotopic prostate cancer model2007
- Author(s)
  Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh NH, Kumon H
- Journal Title
  
  Cancer Gene Ther. 14
  
  Pages: 765-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] T cell immunomonitoring and tumor responses in patients immunized with a complex of cholesterol-bearing hydrophobized pullulan (CHP) and NY-ESO-1 protein.2007
- Author(s)
  Uenaka A, Wada H, Isobe M, Saika T, Tsuji K, Sato E, Sato S, Noguchi Y, Kawabata R, Yasuda T, Doki Y, Kumon H, Iwatsuki K, Shiku H, Monden M, Jungbluth AA, Ritter G, Murphy R, Hoffman E, Old LJ, Nakayama E
- Journal Title
  
  Cancer Immun 7
  
  Pages: 9-9
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients withlocal recurrence of prostate cancer after hormonal therapy2007
- Author(s)
  Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson T.C, Kumon H
- Journal Title
  
  Mol Ther. 15
  
  Pages: 834-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] 前立腺癌-基礎・臨床研究のアップデート-II.臨床研究治療遺伝子治療自殺遺伝子・サイトカイン遺伝子を用いた遺伝子治療2007
- Author(s)
  賀来春紀, 那須保友, 雑賀隆史, 公文裕巳
- Journal Title
  
  日本臨牀 65
  
  Pages: 522-527
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-3.2007
- Author(s)
  Abarzua F, Sakaguchi M, Tanimoto R, Sonegawa H, Li DW, Edamura K, Kobayashi T, Watanabe M, Kashiwakura Y, Kaku H, Saika T, Nakamura K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Mol Med 20(1)
  
  Pages: 37-43
- Data Source
  KAKENHI-PROJECT-19591851
[Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy2007
- Author(s)
  Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson T.C, Kumon H
- Journal Title
  
  Mol Ther 15
  
  Pages: 834-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17659505
[Journal Article] Suicide gene therapy with adenoviral vector delivery of HSV-tk gene and the intravenous administration of ganciclovir for patients with local recurrence of prostate cancer after hormonal therapy2007
- Author(s)
  Nasu Y, Saika T, et al.
- Journal Title
  
  Molecular Therapy (In press)
- NAID
  130004505632
- Data Source
  KAKENHI-PROJECT-17659505
[Journal Article] Therapeutic effects of adoptive splenocyte transfer following in situ AdIL-12 gene therapy in a mouse prostate cancer model.2006
- Author(s)
  Saika T et al.
- Journal Title
  
  Cancer Gene Ther. 13(1)
  
  Pages: 91-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591596
[Journal Article] Therapeutic effects of adoptive splenocyte transfer following in situ AdIL-12 gene therapy in a mouse prostate cancer model.2006
- Author(s)
  Saika T et al.
- Journal Title
  
  Cancer Gene Therapy 13・1
  
  Pages: 91-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591596
[Journal Article] Route of administration influences the antitumor effects of bone marrow-derived dendritic cells engineered to produce interleukin-12 in a metastatic mouse prostate cancer model2004
- Author(s)
  Saika T et al.
- Journal Title
  
  Cancer Gene Therapy 11(5)
  
  Pages: 317-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591596
[Journal Article] Route of administration influences the antitumor effects of bone marrow-derived dendritic cells engineered to produce interleukin-12 in a metastatic mouse prostate cancer model2004
- Author(s)
  Saika T et al.
- Journal Title
  
  Cancer Gene Therapy 11・5
  
  Pages: 317-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591596
[Journal Article] Route of administration influences the antitumor effects of bone marrow-derived dendritic cells engineered to produce interleukin-12 in a metastatic mouse prostate cancer model2004
- Author(s)
  Saika T
- Journal Title
  
  Cancer Gene Therapy 11・5
  
  Pages: 317-324
- Data Source
  KAKENHI-PROJECT-16591596
[Patent] 前立腺癌の骨転移判定方法2018
- Inventor(s)
  今井祐記、雑賀隆史、菊川忠彦、沢田雄一郎
- Industrial Property Rights Holder
  株式会社プラスパブレインズ、今井祐記
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-198404
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] A genetic landscape of de novo neuroendocrine prostate cancer and possible novel therapeutic strategies unveiled by spatial gene expression analysis2024
- Author(s)
  Ryuta Watanabe, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
- Organizer
  2024 AUA Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0135
[Presentation] データ解析を応用した転移性尿路上皮癌治療標的分子の探索2024
- Author(s)
  新井欧介,柳原裕太, 渡辺隆太, 三浦徳宣, 今井祐記, 菊川忠彦, 雑賀隆史
- Organizer
  第33回泌尿器分子細胞研究会
- Data Source
  KAKENHI-PROJECT-23K08759
[Presentation] Exploring the Genomic Landscape of de novo Neuroendocrine Prostate Cancer: Insights for Innovative Therapies from Spatial Gene Expression Analysis2024
- Author(s)
  Ryuta Watanabe, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
- Organizer
  the 39th Annual EAU Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0135
[Presentation] Exploring the Genomic Landscape of de novo Neuroendocrine Prostate Cancer: Insights for Innovative Therapies from Spatial Gene Expression Analysis2024
- Author(s)
  Ryuta Watanabe, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
- Organizer
  AACR Annual Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0135
[Presentation] Prostate-specific membrane antigen expression in endothelial cells of renal tumor-associated neovasculature and risk of recurrence for renal cell carcinoma2024
- Author(s)
  Tadahiko Kikugawa, Keito Kagimoto, Ryuta Watanabe, Noriyoshi Miura, Takashi Saika
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-22K09529
[Presentation] Prostate-specific membrane antigen expression in endothelial cells of renal tumor-associated neovasculature and risk of recurrence for renal cell carcinoma2024
- Author(s)
  Tadahiko Kikugawa, Keito Kagimoto, Ryuta Watanabe, Noriyoshi Miura, Takashi Saika
- Organizer
  2024 ASCO GENITOURINARY CANCERS SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09529
[Presentation] Prostate-Specific Membrane Antigen Expression in Endothelial Cells of Renal Tumor-Associated Neovasculature and Risk of Recurrence for Renal Cell Carcinoma2023
- Author(s)
  Tadahiko Kikugawa, Keito Kagimoto, Ryuta Watanabe, Noriyoshi Miura, Takashi Saika
- Organizer
  The 43rd Congress of the Societe Internationale d`Urologie
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09529
[Presentation] A novel function of a prostate cancer-associated SPOP mutant in topoisomerase 2A-dependent DNA-protein crosslink repair2020
- Author(s)
  Masashi Maekawaa, Ryuta Watanabeb, Miki Hieda, Tomohiko Taguchi, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika and Shigeki Higashiyama
- Organizer
  第79回　日本癌学会　学術総会
- Data Source
  KAKENHI-PROJECT-18K09137
[Presentation] 前立腺癌細胞株LNCaP cellsから放出されるPSMA陽性microvesicleが及ぼす血管内皮細胞の質的変化2019
- Author(s)
  渡辺隆太、前川大志、三浦徳宣、菊川忠彦、雑賀隆史、東山繁樹
- Organizer
  第28回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-18K09137
[Presentation] GPRC5A facilitates cell proliferation and bone metastasis of prostate cancer2019
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balazs Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平雑賀隆史　今井祐記
- Organizer
  第71回西日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] LNCaP cellから放出されるPSMA陽性microvesicleが及ぼす血管内皮細胞の質的変化2019
- Author(s)
  渡辺隆太　前川大志　三浦徳宣　菊川忠彦　東山繁樹　雑賀隆史
- Organizer
  第28回　泌尿器科分子細胞研究会
- Data Source
  KAKENHI-PROJECT-18K09137
[Presentation] GPRC5A facilitates cell proliferation and bone metastasis of prostate cancer2019
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balaz Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平雑賀隆史　今井祐記
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] 前立腺癌細胞株LNCaP cellsから放出されるPSMA陽性microvesicleが及ぼす血管内皮細胞の質的変化2019
- Author(s)
  渡辺隆太、前川大志、三浦徳宣、菊川忠彦、雑賀隆史、東山繁樹
- Organizer
  第60回日本生化学会中国四国支部例会
- Data Source
  KAKENHI-PROJECT-18K09137

1. Kikugawa Tadahiko (70444734)

# of Collaborated Projects: 13 results

# of Collaborated Products: 19 results
2. Miura Noriyoshi (80554427)

# of Collaborated Projects: 10 results

# of Collaborated Products: 14 results
3. 東山繁樹 (60202272)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
4. NASU Yasutomo (20237572)

# of Collaborated Projects: 5 results

# of Collaborated Products: 26 results
5. 今井祐記 (10423873)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
6. 渡辺隆太 (00813635)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
7. EBARA Shin (70379741)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
8. KUMON Hiromi (30144760)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
9. KAKU Haruki (60346426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. KOBUKE Makoto (50452579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. EDAMURA Kohei (90535816)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. Nishimura Kenichi (20868666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 新井欧介 (00972910)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
14. 柳原裕太 (20865703)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. SAKAGUCHI Masakiyo (70379840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. MANABE Daisuke (90379793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 酒井大史 (00820804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中畑和之 (20380256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 飯尾浩之 (80972231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 角田俊雄 (70988435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 沢田雄一郎 (80793554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中村匡徳 (20448046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. HIEDA Miki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. OHKAWA Yasuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 山下政克

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saika Takashi 雑賀 隆史

SAIKA TAKASHI 雑賀 隆史

SAIKA Takashi 雑賀 隆史

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前立腺癌骨転移の分子メカニズム解明と革新的治療法開発への基盤的研究Principal Investigator

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fundamental study for indirect regulattions of skeletal muscle mass by androgen-like action outside of skeletal muscle fibersPrincipal Investigator

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exploring innovative therapeutic target for bone metastatic prostate cancer based on analysis of molecular mechanism.Principal Investigator

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Novel approach with sonoporation in IL12 gene therapy for prostate cancer.Principal Investigator

Saika Takashi 雑賀隆史

SAIKA TAKASHI 雑賀隆史

SAIKA Takashi 雑賀隆史