SUGIMOTO JUN 杉本潤

… Alternative Names

sugimoto jun 杉本潤

Sugimoto Jun 杉本潤

杉本潤スギモトジュン

SUGIMOTO Jun 杉本潤

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Researcher Number	10315476
Other IDs
Affiliation (Current)	2025: 広島大学, 医系科学研究科(医), 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 広島大学, 医系科学研究科(医), 助教 2017 – 2018: 広島大学, 医歯薬保健学研究科(医), 助教 2015 – 2016: 琉球大学, 医学(系)研究科(研究院), 助教 2013: 琉球大学, 医学(系)研究科(研究院), 助教 2005: 琉球大学, 大学院医学研究科, 助手 2003 – 2004: 琉球大学, 大学院・医学研究科, 助手 2002: 琉球大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Human genetics / Human genetics Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Psychiatric science
Keywords	Principal Investigator 細胞融合 / サプレシン / 胎盤 / 内在性レトロウイルス / 細胞融合抑制 / trophoblast / cell fusion / suppressyn / 胎盤絨毛細胞 / ポリクローナル抗体 … More / 甲状腺 / 膵臓 / ヒト内在性レトロウイルス / サプレシン特異的ELISAアッセイ / 早発型妊娠高血圧腎症 / 妊娠高血圧症候群(HDP) / trophoblsat / 妊娠高血圧症候群 / HERV / ダウン症候群 / 胎児発育不全 / 妊娠高血圧腎症 / 胎盤トロホブラスト細胞 / ノックアウトマウス / 細胞融合抑制タンパク / シンシチン / 絨毛初代培養細胞 / 免疫組織染色法 / モノクローナル抗体 … More Except Principal Investigator RNAi / 浸潤 / 合胞体化 / 胎盤絨毛細胞 / 癒着胎盤 / 妊娠高血圧症候群 / シンシチウム化 / トロフォブラスト / 胎盤 / human endogenous retroviruses / DNA methylation / environmental factors / genetic factors / psychiatric disorders / 内在性レトロウイルス / メチル化 / 環境要因 / 遺伝要因 / 精神疾患 Less

早発型妊娠高血圧腎症発症原因タンパクとしてのサプレシン機能解析Principal Investigator
- Principal Investigator
  
  杉本潤
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Hiroshima University
Study on the mechanisms of trophoblast syncytialisation: implication for the pathogenesis of preeclampsia
- Principal Investigator
  
  Kudo Yoshiki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Hiroshima University
Functional Analysis of Suppressyn as a Causative Protein in Disorders with Placental HypoplasiaPrincipal Investigator
- Principal Investigator
  
  sugimoto jun
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Hiroshima University
Establishment of murine knock-out model for cell fusion suppressor: suppressynPrincipal Investigator
- Principal Investigator
  
  sugimoto jun
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Hiroshima University
  University of the Ryukyus
In vivo functional analysis of cell fusion suppressor : SuppressynPrincipal Investigator
- Principal Investigator
  
  Sugimoto Jun
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of the Ryukyus
腺組織に発現するヒト内在性レトロウイルスのMHC抗原提示抑制機構の検証Principal Investigator
- Principal Investigator
  
  杉本潤
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  University of the Ryukyus
DNA Methylation and Human Endogenous Retroviruses Linking Genetic and Environmental Factors in the Pathogenesis of Psychiatric Disorders
- Principal Investigator
  
  JINNO Yoshihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of the Ryukyus
膵臓及び甲状腺に特異的に発現する内在性レトロウイルスの機能解析Principal Investigator
- Principal Investigator
  
  杉本潤
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  University of the Ryukyus

All 2024 2023 2022 2021 2020 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] The Role of the Placental Enzyme Indoleamine 2,3-Dioxygenase in Normal and Abnormal Human Pregnancy2024
- Author(s)
  Kudo Yoshiki、Sugimoto Jun
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 8 Pages: 4577-4577
- DOI
  10.3390/ijms25084577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09450
[Journal Article] Controlling Trophoblast Cell Fusion in the Human Placenta - Transcriptional Regulation of Suppressyn, an Endogenous Inhibitor of Syncytin-12023
- Author(s)
  Sugimoto Jun、Schust Danny J.、Sugimoto Makiko、Jinno Yoshihiro、Kudo Yoshiki
- Journal Title
  
  Biomolecules
  
  Volume: 13 Issue: 11 Pages: 1627-1627
- DOI
  10.3390/biom13111627
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09450
[Journal Article] Involvement of the HERV-derived　cell-fusion inhibitor, suppressyn, in the fusion defects characteristic of the trisomy 21 placenta2022
- Author(s)
  Sugimoto J, Schust DJ, Yamazaki T, Kudo Y
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 10552-10552
- DOI
  10.1038/s41598-022-14104-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09450, KAKENHI-PROJECT-20K09644
[Journal Article] Could the Human Endogenous Retrovirus-Derived Syncytialization Inhibitor, Suppressyn, Limit Heterotypic Cell Fusion Events in the Decidua?2021
- Author(s)
  Sugimoto Jun、Choi Sehee、Sheridan Megan A.、Koh Iemasa、Kudo Yoshiki、Schust Danny J.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 19 Pages: 10259-10259
- DOI
  10.3390/ijms221910259
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09644, KAKENHI-PROJECT-21K09450
[Journal Article] The Immunology of Syncytialized Trophoblast2021
- Author(s)
  Schust Danny J.、Bonney Elizabeth A.、Sugimoto Jun、Ezashi Toshi、Roberts R. Michael、Choi Sehee、Zhou Jie
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 4 Pages: 1767-1767
- DOI
  10.3390/ijms22041767
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09644
[Journal Article] Syncytins expressed in human placental trophoblast2021
- Author(s)
  Roberts R. Michael、Ezashi Toshihiko、Schulz Laura C.、Sugimoto Jun、Schust Danny J.、Khan Teka、Zhou Jie
- Journal Title
  
  Placenta
  
  Volume: 113 Pages: 8-14
- DOI
  10.1016/j.placenta.2021.01.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09644
[Journal Article] A novel human endogenous retroviral protein inhibits cell-cell fusion2013
- Author(s)
  Sugimoto J, Sugimoto M, Bernstein H, Jinno Y, Schust D
- Journal Title
  
  Scientific Reports
  
  Volume: 3:1462 Issue: 1
- DOI
  10.1038/srep01462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462567
[Presentation] 早発型妊娠高血圧腎症と胎児発育不全に認められる細胞融合抑制タンパク：サプレシンの発現異常2023
- Author(s)
  杉本潤、永松健、Danny Schust、山﨑友美、工藤美樹
- Organizer
  第31回日本胎盤学会
- Data Source
  KAKENHI-PROJECT-21K09450
[Presentation] サプレシン：網羅的遺伝子解析により同定した胎盤トロホブラスト形成に関わる分子2023
- Author(s)
  杉本潤
- Organizer
  第75回日本産科婦人科学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09450
[Presentation] Deletion of a mouse retrovirus-derived cell fusion suppressor gene induces abnormal placental formation2022
- Author(s)
  Jun Sugimoto, Yoshiki Kudo
- Organizer
  第74回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09644
[Presentation] syncytin-1/suppressyn遺伝子発現比は早期型妊娠高血圧腎症発症に相関する2022
- Author(s)
  杉本潤、永松健、Danny Schust、矢野絵里子、山﨑友美、工藤美樹
- Organizer
  第30回日本胎盤学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09644
[Presentation] Deletion of a mouse retrovirus-derived cell fusion suppressor gene induces abnormal placental formation2022
- Author(s)
  Jun Sugimoto, Yoshiki Kudo
- Organizer
  第74回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09450
[Presentation] 内在性レトロウイルス由来細胞融合抑制遺伝子を欠損したマウスは胎盤形成異常と胎児発育不全を示す2021
- Author(s)
  杉本潤、Schust Danny、工藤美樹
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09450
[Presentation] Expression of the cell fusion inhibitor, Suppressyn, in hypertensive disorders of pregnancy2021
- Author(s)
  Jun Sugimoto, Tomomi Yamazaki, Yuriko Omori, Yoshiki Kudo
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09450
[Presentation] Expression of the cell fusion inhibitor, Suppressyn, in hypertensive disorders of pregnancy2021
- Author(s)
  Jun Sugimoto, Tomomi Yamazaki, Yuriko Omori, Yoshiki Kudo
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09644
[Presentation] 内在性レトロウイルス由来細胞融合抑制遺伝子を欠損したマウスは胎盤形成異常と胎児発育不全を示す2021
- Author(s)
  杉本　潤、Danny J. Schust、工藤美樹
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09644
[Presentation] 胎盤形成とヒト内在性レトロウイルス由来タンパク：サプレシン2020
- Author(s)
  杉本潤
- Organizer
  日本胎盤学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09644
[Presentation] 内在性レトロウイルス：胎盤での発現とその生理学的意義2017
- Author(s)
  杉本潤、Danny Schust
- Organizer
  日本胎盤学会
- Data Source
  KAKENHI-PROJECT-16K11097
[Presentation] 胎盤絨毛初代培養細胞の包括的遺伝子発現解析2017
- Author(s)
  杉本　潤、金城忠嗣、松波雅俊、木村亮介、青木陽一、陣野吉廣、Danny Schust
- Organizer
  日本胎盤学会
- Data Source
  KAKENHI-PROJECT-16K11097
[Presentation] マウスサプレシン遺伝子の単離・同定2016
- Author(s)
  杉本　潤、Schust Danny、中川草、小田高也、陣野吉廣
- Organizer
  日本胎盤学会
- Place of Presentation
  ホテルアバローム紀の国（和歌山県、和歌山市）
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K11097
[Presentation] 絨毛初代培養細胞を用いたサプレシンの発現・機能解析2015
- Author(s)
  杉本　潤、金城忠嗣、Schust Danny、小田高也、青木陽一、陣野吉廣
- Organizer
  第23回日本胎盤学会
- Place of Presentation
  JA共済ビル(東京都千代田区)
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-25462567
[Presentation] Could a novel, retrovirally-derived inhibitor of trophoblast syncytialization play a role in limiting cell fusion between extravillous trophoblast and maternal decidua?2013
- Author(s)
  Danny J. Schust, Jun Sugimoto, Takaya Oda and Yoshihiro Jinno
- Organizer
  European Society of Human Reproduction & Embryology
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-25462567
[Presentation] 細胞融合抑制タンパクをコードするHERV-Fb1遺伝子で見つかった６種類の遺伝子型の機能解析2013
- Author(s)
  杉本　潤、小田高也、Danny Schust、陣野吉廣
- Organizer
  第21回日本胎盤学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-25462567

1. JINNO Yoshihiro (20179097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Kudo Yoshiki (80241082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 古宇家正 (10794779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SUGIMOTO JUN 杉本 潤

sugimoto jun 杉本 潤

Sugimoto Jun 杉本 潤

杉本 潤 スギモト ジュン

SUGIMOTO Jun 杉本 潤

Research Projects

Research Products

Co-Researchers

早発型妊娠高血圧腎症発症原因タンパクとしてのサプレシン機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the mechanisms of trophoblast syncytialisation: implication for the pathogenesis of preeclampsia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional Analysis of Suppressyn as a Causative Protein in Disorders with Placental HypoplasiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of murine knock-out model for cell fusion suppressor: suppressynPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo functional analysis of cell fusion suppressor : SuppressynPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腺組織に発現するヒト内在性レトロウイルスのMHC抗原提示抑制機構の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA Methylation and Human Endogenous Retroviruses Linking Genetic and Environmental Factors in the Pathogenesis of Psychiatric Disorders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

膵臓及び甲状腺に特異的に発現する内在性レトロウイルスの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Role of the Placental Enzyme Indoleamine 2,3-Dioxygenase in Normal and Abnormal Human Pregnancy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Controlling Trophoblast Cell Fusion in the Human Placenta - Transcriptional Regulation of Suppressyn, an Endogenous Inhibitor of Syncytin-12023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of the HERV-derived cell-fusion inhibitor, suppressyn, in the fusion defects characteristic of the trisomy 21 placenta2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Could the Human Endogenous Retrovirus-Derived Syncytialization Inhibitor, Suppressyn, Limit Heterotypic Cell Fusion Events in the Decidua?2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Immunology of Syncytialized Trophoblast2021

Author(s)

Journal Title

DOI

SUGIMOTO JUN 杉本潤

sugimoto jun 杉本潤

Sugimoto Jun 杉本潤

杉本潤スギモトジュン

SUGIMOTO Jun 杉本潤

[Journal Article] Involvement of the HERV-derived　cell-fusion inhibitor, suppressyn, in the fusion defects characteristic of the trisomy 21 placenta2022