MATSUSHITA Kenichi 松下健一

… Alternative Names

松下健一マツシタケンイチ

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Researcher Number	10317133
Other IDs
Affiliation (based on the past Project Information) *help	2023: 埼玉医科大学, 医学部, 教授 2020 – 2022: 熊本大学, 病院, 特任教授 2019: 杏林大学, 医学部, 准教授 2014 – 2018: 杏林大学, 医学部, 講師 2009 – 2010: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Cardiovascular medicine / Basic Section 53020:Cardiology-related / Circulatory organs internal medicine
Keywords	Principal Investigator 循環器 / 心不全 / トランスレーショナルリサーチ / 左房 / 肥満 / 左室駆出分画 / 発生・分化 / 再生医学

Research Projects
(4 results)
Research Products
(32 results)

肥満型心不全の分子機構の解明とその制御Principal Investigator
- Principal Investigator
  
  松下健一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Saitama Medical University
  Kumamoto University
Translational research to clarify the pathophysiology of and develop new therapies for heart failure with preserved ejection fractionPrincipal Investigator
- Principal Investigator
  
  Matsushita Kenichi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kumamoto University
  Kyorin University
Elucidation of the pathophysiology of acute heart failure and development of novel therapies based on clinical data and epigeneticsPrincipal Investigator
- Principal Investigator
  
  MATSUSHITA Kenichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyorin University
アンジオテンシン受容体遮断の心筋分化に対する効果Principal Investigator
- Principal Investigator
  
  松下健一
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2010

All Journal Article Presentation

[Journal Article] Prognostic impact of diabetes mellitus on in-hospital mortality in patients with acute myocardial infarction complicating renal dysfunction according to age and sex2023
- Author(s)
  Matsushita K, Kojima S, Hirakawa K, Tabata N, Ito M, Yamanaga K, Fujisue K, Hoshiyama T, Hanatani S, Sueta D, Kanazawa H, Takashio S, Arima Y, Araki S, Usuku H, Suzuki S, Yamamoto E, Nakamura T, Soejima H, Kaikita K, Tsujita K.
- Journal Title
  
  Hellenic Journal of Cardiology
  
  Volume: Online ahead of print Pages: 15-25
- DOI
  10.1016/j.hjc.2023.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08109
[Journal Article] Comparison of the prognostic value of lateral versus septal early mitral annulus velocity in patients with acute decompensated heart failure2023
- Author(s)
  Matsushita K, Minamishima T, Sakata K, Satoh T, Soejima K.
- Journal Title
  
  The International Journal of Cardiovascular Imaging
  
  Volume: 39 Issue: 4 Pages: 707-714
- DOI
  10.1007/s10554-022-02770-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08109
[Journal Article] Predicting readmission for heart failure patients by echocardiographic assessment of elevated left atrial pressure2023
- Author(s)
  Matsushita K, Ito J, Isaka A, Higuchi S, Minamishima T, Sakata K, Satoh T, Soejima K.
- Journal Title
  
  The American Journal of the Medical Sciences
  
  Volume: 366 Issue: 5 Pages: 360-366
- DOI
  10.1016/j.amjms.2023.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08109
[Journal Article] Differential effects of overweight/obesity depending on the severity of heart failure complicating acute myocardial infarction in Japan2022
- Author(s)
  Matsushita K, Kojima S, Hirakawa K, Tabata N, Ito M, Yamanaga K, Fujisue K, Hoshiyama T, Hanatani S, Sueta D, Kanazawa H, Takashio S, Arima Y, Araki S, Usuku H, Suzuki S, Yamamoto E, Nakamura T, Soejima H, Kaikita K, Tsujita K.
- Journal Title
  
  Progress in Cardiovascular Diseases
  
  Volume: Online ahead of print Pages: 49-57
- DOI
  10.1016/j.pcad.2022.11.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08109
[Journal Article] Heart Failure and Adipose Mesenchymal Stem Cells2020
- Author(s)
  Matsushita Kenichi
- Journal Title
  
  Trends in Molecular Medicine
  
  Volume: 26 Issue: 4 Pages: 369-379
- DOI
  10.1016/j.molmed.2020.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09523
[Journal Article] Reply to: Heart Failure With Preserved Ejection Fraction in Older Adults2020
- Author(s)
  Matsushita Kenichi、Harada Kazumasa、Miyazaki Tetsuro、Miyamoto Takamichi、Kohsaka Shun、Iida Kiyoshi、Yamamoto Yoshiya、Nagatomo Yuji、Yoshino Hideaki、Yamamoto Takeshi、Nagao Ken、Takayama Morimasa
- Journal Title
  
  Journal of the American Geriatrics Society
  
  Volume: 68 Issue: 3 Pages: 665-666
- DOI
  10.1111/jgs.16301
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09523, KAKENHI-PROJECT-19K11774
[Journal Article] Urinary cast is a useful predictor of acute kidney injury in acute heart failure2019
- Author(s)
  Higuchi Satoshi、Kabeya Yusuke、Matsushita Kenichi、Yamasaki Satoko、Ohnishi Hiroaki、Yoshino Hideaki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 4352-4352
- DOI
  10.1038/s41598-019-39470-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09523, KAKENHI-PROJECT-17K18085
[Journal Article] Prognostic factors for one-year mortality in patients with acute heart failure with and without chronic kidney disease: differential impact of beta-blocker and diuretic treatments2019
- Author(s)
  Matsushita Kenichi、Minamishima Toshinori、Sakata Konomi、Satoh Toru、Yoshino Hideaki
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 7 Pages: 1011-1018
- DOI
  10.1038/s41440-018-0204-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09523
[Journal Article] Younger‐ vs Older‐Old Patients with Heart Failure with Preserved Ejection Fraction2019
- Author(s)
  Matsushita Kenichi、Harada Kazumasa、Miyazaki Tetsuro、Miyamoto Takamichi、Kohsaka Shun、Iida Kiyoshi、Yamamoto Yoshiya、Nagatomo Yuji、Yoshino Hideaki、Yamamoto Takeshi、Nagao Ken、Takayama Morimasa
- Journal Title
  
  Journal of the American Geriatrics Society
  
  Volume: 67 Issue: 10 Pages: 2123-2128
- DOI
  10.1111/jgs.16050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09523, KAKENHI-PROJECT-19K11774
[Journal Article] Different prognostic associations of beta-blockers and diuretics in heart failure with preserved ejection fraction with versus without high blood pressure2019
- Author(s)
  Matsushita Kenichi、Harada Kazumasa、Miyazaki Tetsuro、Miyamoto Takamichi、Kohsaka Shun、Iida Kiyoshi、Tanimoto Shuzou、Takei Makoto、Hosoda Toru、Yamamoto Yoshiya、Shiraishi Yasuyuki、Yoshino Hideaki、Yamamoto Takeshi、Nagao Ken、Takayama Morimasa
- Journal Title
  
  Journal of Hypertension
  
  Volume: 37 Issue: 3 Pages: 643-649
- DOI
  10.1097/hjh.0000000000001932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09523, KAKENHI-PROJECT-15K00845, KAKENHI-PROJECT-19K11774
[Journal Article] Effects of glycemic control on in-hospital mortality among acute heart failure patients with reduced, mid-range, and preserved ejection fraction2018
- Author(s)
  Matsushita Kenichi、Harada Kazumasa、Miyazaki Tetsuro、Miyamoto Takamichi、Iida Kiyoshi、Tanimoto Shuzou、Yagawa Mayuko、Takei Makoto、Nagatomo Yuji、Hosoda Toru、Yoshino Hideaki、Yamamoto Takeshi、Nagao Ken、Takayama Morimasa
- Journal Title
  
  Heart and Vessels
  
  Volume: 33 Issue: 9 Pages: 1022-1028
- DOI
  10.1007/s00380-018-1152-2
- NAID
  40022187675
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09523, KAKENHI-PROJECT-15K00845
[Journal Article] Estimated Pulmonary Artery Systolic Pressure and Mortality in Older-Elderly Heart Failure Patients2018
- Author(s)
  Matsushita Kenichi、Sakata Konomi、Satoh Toru、Yoshino Hideaki
- Journal Title
  
  Journal of the American Geriatrics Society
  
  Volume: 67 Issue: 2 Pages: 323-328
- DOI
  10.1111/jgs.15663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09523
[Journal Article] Importance of Carefulness in Accurate Diagnosis2018
- Author(s)
  Higuchi Satoshi、Matsushita Kenichi、Niina Yoshihiro、Sakata Konomi、Satoh Toru、Yoshino Hideaki
- Journal Title
  
  Int. Heart J.
  
  Volume: 59 Issue: 4 Pages: 845-847
- DOI
  10.1536/ihj.17-345
- NAID
  130007428507
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2018-07-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09523
[Journal Article] Considerations in cardio-oncology: Multiple mobile left-sided cardiac thrombi in chemotherapy-induced cardiomyopathy2017
- Author(s)
  Minamishima Toshinori、Matsushita Kenichi、Morikubo Hiromu、Isaka Aoi、Matsushita Noriko、Endo Hidehito、Kubota Hiroshi、Sakata Konomi、Satoh Toru、Yoshino Hideaki
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 23 Issue: 7 Pages: 488-492
- DOI
  10.1016/j.jiac.2017.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09523
[Journal Article] Mesenchymal stem cells in obesity: insights for translational applications.2017
- Author(s)
  Matsushita K, Dzau VJ.
- Journal Title
  
  Lab Invest
  
  Volume: 97 Issue: 10 Pages: 1158-1166
- DOI
  10.1038/labinvest.2017.42
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Differences in predictors of one-year mortality between patients with hypertensive and non-hypertensive acute heart failure: Usefulness of E/E' in hypertensive heart failure.2017
- Author(s)
  Matsushita K, Minamishima T, Sakata K, Satoh T, Yoshino H.
- Journal Title
  
  Eur J Intern Med
  
  Volume: 38 Pages: e13-e14
- DOI
  10.1016/j.ejim.2016.10.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Effect of Heart Failure Secondary to Ischemic Cardiomyopathy on Body Weight and Blood Pressure2017
- Author(s)
  Matsushita Kenichi、Harada Kazumasa、Miyazaki Tetsuro、Miyamoto Takamichi、Kohsaka Shun、Iida Kiyoshi、Tanimoto Shuzou、Yagawa Mayuko、Shiraishi Yasuyuki、Yoshino Hideaki、Yamamoto Takeshi、Nagao Ken、Takayama Morimasa
- Journal Title
  
  The American Journal of Cardiology
  
  Volume: 120 Issue: 9 Pages: 1589-1594
- DOI
  10.1016/j.amjcard.2017.07.054
- NAID
  40021784800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09523
[Journal Article] Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling.2016
- Author(s)
  Matsushita K, Wu Y, Pratt RE, Dzau VJ.
- Journal Title
  
  Lab Invest
  
  Volume: 96 Issue: 8 Pages: 909-917
- DOI
  10.1038/labinvest.2016.66
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Pathogenetic pathways of cardiorenal syndrome and their possible therapeutic implications.2016
- Author(s)
  Matsushita K.
- Journal Title
  
  Curr Pharm Des
  
  Volume: 22 Issue: 30 Pages: 4629-4637
- DOI
  10.2174/1381612822666160510125057
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Nuclear hormone receptor LXRα inhibits adipocyte differentiation of mesenchymal stem cells with Wnt/beta-catenin signaling.2016
- Author(s)
  Matsushita K, Morello F, Zhang Z, Masuda T, Iwanaga S, Steffensen KR, Gustafsson JA, Pratt RE, Dzau VJ
- Journal Title
  
  Lab Invest
  
  Volume: 96 Issue: 2 Pages: 230-238
- DOI
  10.1038/labinvest.2015.141
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Mesenchymal stem cells and metabolic syndrome: current understanding and potential clinical implications.2016
- Author(s)
  Matsushita K.
- Journal Title
  
  Stem Cells Int
  
  Volume: 2016 Issue: 1 Pages: 2892840-2892840
- DOI
  10.1155/2016/2892840
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Successful treatment of severe right-sided heart failure due to postoperative constrictive pericarditis with tolvaptan.2016
- Author(s)
  Kanaya M, Matsushita K, Inami T, Yamasaki S, Mizumi S, Minamishima T, Goda A, Ueda A, Sakata K, Satoh T, Yoshino H.
- Journal Title
  
  Am J Ther
  
  Volume: 23 Issue: 1 Pages: e264-e267
- DOI
  10.1097/mjt.0000000000000146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Comparison of risk factors for acute worsening renal function in heart failure patients with and without preserved ejection fraction.2015
- Author(s)
  Yamagishi T, Matsushita K, Minamishima T, Goda A, Sakata K, Satoh T, Yoshino H.
- Journal Title
  
  Eur J Intern Med
  
  Volume: 26 Issue: 8 Pages: 599-602
- DOI
  10.1016/j.ejim.2015.08.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Comparison of the reliability of E/E' to estimate pulmonary capillary wedge pressure in heart failure patients with preserved ejection fraction versus those with reduced ejection fraction.2015
- Author(s)
  Matsushita K, Minamishima T, Goda A, Ishiguro H, Kosho H, Sakata K, Satoh T, Yoshino H.
- Journal Title
  
  Int J Cardiovasc Imaging
  
  Volume: 31 Issue: 8 Pages: 1497-1502
- DOI
  10.1007/s10554-015-0718-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Blockade of angiotensin II type 2 receptor by PD123319 inhibits osteogenic differentiation of human mesenchymal stem cells via inhibition of extracellular signal-regulated kinase signaling.2015
- Author(s)
  Matsushita K, Wu Y, Pratt RE, Dzau VJ.
- Journal Title
  
  J Am Soc Hypertens
  
  Volume: 9 Issue: 7 Pages: 517-525
- DOI
  10.1016/j.jash.2015.06.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] 急性心不全2014
- Author(s)
  松下健一
- Journal Title
  
  杏林医学会雑誌
  
  Volume: 45 Pages: 165-169
- NAID
  130004903276
- Data Source
  KAKENHI-PROJECT-26461086
[Journal Article] Mesenchymal stem cells differentiate into renin producing juxtaglomerular (JG)-like cells under the control of LXRα2010
- Author(s)
  Kenichi Matsushita, et al.
- Journal Title
  
  THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL.285
  
  Pages: 11974-11982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790745
[Presentation] 心エコー図による左房圧上昇推定の心不全再入院予測における有用性2022
- Author(s)
  松下健一, 伊藤準之助, 井坂葵, 樋口聡, 南島俊徳, 坂田好美, 佐藤徹, 副島京子
- Organizer
  日本超音波医学会第95回学術集会
- Data Source
  KAKENHI-PROJECT-21K08109
[Presentation] Prognostic impact of diabetes mellitus on in-hospital mortality in patients with acute myocardial infarction and renal dysfunction2021
- Author(s)
  Matsushita Kenichi, Kojima Sunao, Tabata Noriaki, Yamamoto Eiichiro, Kaikita Koichi, Tsujita Kenichi
- Organizer
  第85回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09523
[Presentation] Prognostic factors for one-year mortality in patients with acute heart failure with and without chronic kidney disease: Differential impact of beta-blocker and diuretic treatments2018
- Author(s)
  Matsushita Kenichi、Minamishima Toshinori、Sakata Konomi、Satoh Toru、Yoshino Hideaki
- Organizer
  Heart Failure 2018 & World Congress on Acute Heart Failure (Annual Congress of the Heart Failure Association of the European Society of Cardiology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09523
[Presentation] Differences in predictors of one-year mortality between patients with hypertensive and non-hypertensive acute heart failure: Usefulness of E/E' in hypertensive heart failure.2016
- Author(s)
  Matsushita K, Minamishima T, Sakata K, Satoh T, Yoshino H.
- Organizer
  The 26th European Meeting on Hypertension and Cardiovascular Protection
- Place of Presentation
  Paris (France)
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461086
[Presentation] Differences between patients with diastolic heart failure and those with systolic heart failure in the way that hypertension is involved in acute worsening renal function2015
- Author(s)
  Yamagishi T, Matsushita K, Minamishima T, Goda A, Sakata K, Satoh T, Yoshino H.
- Organizer
  25th European Meeting on Hypertension and Cardiovascular Protection
- Place of Presentation
  Milan (Italy)
- Year and Date
  2015-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461086

MATSUSHITA Kenichi 松下 健一

松下 健一 マツシタ ケンイチ

Research Projects

Research Products

肥満型心不全の分子機構の解明とその制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Translational research to clarify the pathophysiology of and develop new therapies for heart failure with preserved ejection fractionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the pathophysiology of acute heart failure and development of novel therapies based on clinical data and epigeneticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アンジオテンシン受容体遮断の心筋分化に対する効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prognostic impact of diabetes mellitus on in-hospital mortality in patients with acute myocardial infarction complicating renal dysfunction according to age and sex2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of the prognostic value of lateral versus septal early mitral annulus velocity in patients with acute decompensated heart failure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predicting readmission for heart failure patients by echocardiographic assessment of elevated left atrial pressure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential effects of overweight/obesity depending on the severity of heart failure complicating acute myocardial infarction in Japan2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heart Failure and Adipose Mesenchymal Stem Cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply to: Heart Failure With Preserved Ejection Fraction in Older Adults2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary cast is a useful predictor of acute kidney injury in acute heart failure2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic factors for one-year mortality in patients with acute heart failure with and without chronic kidney disease: differential impact of beta-blocker and diuretic treatments2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Younger‐ vs Older‐Old Patients with Heart Failure with Preserved Ejection Fraction2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Different prognostic associations of beta-blockers and diuretics in heart failure with preserved ejection fraction with versus without high blood pressure2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of glycemic control on in-hospital mortality among acute heart failure patients with reduced, mid-range, and preserved ejection fraction2018

Author(s)

MATSUSHITA Kenichi 松下健一

松下健一マツシタケンイチ