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NOJIRI Hidetoshi  野尻 英俊

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… Alternative Names

野尻 英俊  ノジリ ヒデトシ

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Researcher Number 10317456
Affiliation (Current) 2025: 順天堂大学, 医学部, 先任准教授
Affiliation (based on the past Project Information) *help 2025: 順天堂大学, 医学部, 先任准教授
2023: 順天堂大学, 医学部, 先任准教授
2022: 順天堂大学, 医学部, 准教授
2014 – 2020: 順天堂大学, 医学部, 准教授
2014: 順天堂大学, 整形外科, 助教
2009 – 2013: Juntendo University, 医学部, 助教
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Orthopaedic surgery
Keywords
Principal Investigator
酸化ストレス / スーパーオキシド / 変性 / SOD / 加齢 / 脊柱後弯症 / 女性 / 筋力低下 / 傍脊柱筋 / 老化 … More / SOD活性 / サプリメント / 健康食品 / GliSODin / 運動器 / Sod2 / メカニカルストレス / 変形性関節症 / 軟骨 / Sod1 / 廃用性骨萎縮 / SOD1 / 骨萎縮 / 廃用 / 骨・軟骨代謝学 / 運動能力 / モデルマウス / 走行能力 / ATP / ミトコンドリア / 骨格筋 / Mn-SOD … More
Except Principal Investigator
酸化ストレス / 骨粗鬆症 / 老化 / 骨格筋 / SOD / 骨 / 骨代謝 / 加齢 / 破骨細胞 / 骨芽細胞 / Mn-SOD / 骨細胞 / 活性酸素 / CuZn-SOD / モデルマウス / 遺伝子 / スーパーオキサイドディスムターゼ(SOD) Less
  • Research Projects

    (9 results)
  • Research Products

    (62 results)
  • Co-Researchers

    (5 People)
  •  脊柱管狭窄の黄色靭帯変化における酸化ストレスの病理的意義の解明Principal Investigator

    • Principal Investigator
      野尻 英俊
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Juntendo University
  •  脊柱後弯症における傍脊柱筋内酸化ストレスの病理的意義の解明Principal Investigator

    • Principal Investigator
      野尻 英俊
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Juntendo University
  •  Verification of the usefulness of oxidative stress regulation for functional decline associated with age-related degeneration of locomotive organsPrincipal Investigator

    • Principal Investigator
      Nojiri Hidetoshi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Juntendo University
  •  Pathological role of mitochondrial oxidative stress in cartilage degenerationPrincipal Investigator

    • Principal Investigator
      Nojiri Hidetoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Juntendo University
  •  Oxidative stress in bone regulates skeletal homeostasis in mice

    • Principal Investigator
      Shimizu Takahiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Chiba University
  •  The role of oxidative stress in the maintenance of bone metabolism

    • Principal Investigator
      SAITA Yoshitomo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Juntendo University
  •  Analysis of pathological role of cytoplasmic oxidative stress in disuse bone atrophy.Principal Investigator

    • Principal Investigator
      NOJIRI Hidetoshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Juntendo University
  •  Molecular analysis for oxidative stress-induced senescent motor weaknessPrincipal Investigator

    • Principal Investigator
      NOJIRI Hidetoshi
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Juntendo University
  •  The development and analyses of the mouse model of age-related osteoporosis.

    • Principal Investigator
      SAITA Yoshitomo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Juntendo University

All 2024 2023 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

  • [Book] Systems Biology of Free Radicals and Antioxidants2014

    • Author(s)
      Shimizu T, Nojiri H, et al.
    • Publisher
      Springer-Verlag Berlin Heidelberg
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Book] Aging: Oxidative Stress and Dietary Antioxidants2014

    • Author(s)
      Shibuya S, Nojiri H, et al.
    • Publisher
      Elsevier Inc.
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Journal Article] Decreased grip strength is associated with paraspinal muscular oxidative stress in female lumbar degenerative disease patients2024

    • Author(s)
      Takahashi Ryosuke、Nojiri Hidetoshi、Ohara Yukoh、Fujiwara Toshiyuki、Ishijima Muneaki
    • Journal Title

      Journal of Orthopaedic Research

      Volume: - Issue: 10 Pages: 2287-2295

    • DOI

      10.1002/jor.25863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09409
  • [Journal Article] Association of Superoxide‐Induced Oxidative Stress With Rotator Cuff Tears in Human Patients2019

    • Author(s)
      Yoshida Keiichi、Itoigawa Yoshiaki、Wada Tomoki、Maruyama Yuichiro、Nojiri Hidetoshi、Kawasaki Takayuki、Kaneko Kazuo
    • Journal Title

      Journal of Orthopaedic Research

      Volume: 38 Issue: 1 Pages: 212-218

    • DOI

      10.1002/jor.24472

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09081, KAKENHI-PROJECT-18K18371, KAKENHI-PROJECT-17K10942
  • [Journal Article] Antioxidant treatment with vitamin C attenuated rotator cuff degeneration caused by oxidative stress in Sod1-deficient mice.2018

    • Author(s)
      30.Morikawa D, Nojiri H, Itoigawa Y, Ozawa Y, Kaneko K, Shimizu T.
    • Journal Title

      JSES Open Access

      Volume: 2 Issue: 1 Pages: 91-96

    • DOI

      10.1016/j.jses.2017.11.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10942
  • [Journal Article] Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage2018

    • Author(s)
      Koike M, Nojiri H, Kanazawa H, Yamaguchi H, Miyagawa K, Nagura N, Banno S, Iwase Y, Kurosawa H, Kaneko K.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 9 Pages: e0203944-e0203944

    • DOI

      10.1371/journal.pone.0203944

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10942, KAKENHI-PROJECT-17K16704
  • [Journal Article] Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes.2018

    • Author(s)
      Masuda I, Koike M, Nakashima S, Mizutani Y, Ozawa Y, Watanabe K, Sawada Y, Sugiyama H, Sugimoto A, Nojiri H, Sashihara K, Yokote K, Shimizu T
    • Journal Title

      Sci Rep.

      Volume: 8 Issue: 1 Pages: 7229-7229

    • DOI

      10.1038/s41598-018-25348-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10942, KAKENHI-PROJECT-17H01558
  • [Journal Article] Brain-specific superoxide dismutase 2 deficiency causes perinatal death with spongiform encephalopathy in mice.2015

    • Author(s)
      Izuo, N., Nojiri, H., Uchiyama, S., Noda, Y., Kawakami, S., Kojima, S., Sasaki, T., Shirasawa, T., Shimizu, T.
    • Journal Title

      Oxid. Med. Cell. Longev

      Volume: 2015 Pages: 238914-238914

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Journal Article] Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration2015

    • Author(s)
      Koike, M., Nojiri, H., Ozawa, Y., Watanabe, K., Muramatsu, Y., Kaneko, H., Morikawa, D., Kobayashi, K., Saita, Y., Sasho, T., Shirasawa, T., Yokote, K., Kaneko, K., Shimizu, T.
    • Journal Title

      Sci. Rep.

      Volume: 5 Issue: 1 Pages: 11722-11722

    • DOI

      10.1038/srep11722

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-26462319, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
  • [Journal Article] Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis.2015

    • Author(s)
      Kobayashi K1, Nojiri H2, Saita Y2, Morikawa D1, Ozawa Y3, Watanabe K3, Koike M1, Asou Y4, Shirasawa T5, Yokote K6, Kaneko K2, Shimizu T3.
    • Journal Title

      Scientific Reports

      Volume: Mar 16;5 Issue: 1 Pages: 9148-9148

    • DOI

      10.1038/srep09148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791568, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-26462319, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
  • [Journal Article] Brain-specific superoxide dismutase 2 deficiency causes perinatal death with spongiform encephalopathy in mice.2015

    • Author(s)
      Izuo, N., Nojiri, H., Uchiyama, S., Noda, Y., Kawakami, S., Kojima, S., Sasaki, T., Shirasawa, T., Shimizu, T.
    • Journal Title

      Oxid. Med. Cell. Longev.

      Volume: 2015 Pages: 238914-238914

    • DOI

      10.1155/2015/238914

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-26462319, KAKENHI-PROJECT-15K19279
  • [Journal Article] Superoxide dismutase 1 loss disturbs intracellular redox signaling, resulting in global age-related pathological changes.2014

    • Author(s)
      Watanabe, K., Shibuya, S., Ozawa, Y., Nojiri, H., Izuo, N., Yokote, K., and Shimizu, T.
    • Journal Title

      BioMed. Res. Int.

      Volume: 2014 Pages: 140165-140165

    • DOI

      10.1155/2014/140165

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Journal Article] Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading2013

    • Author(s)
      Morikawa D, Nojiri H, Saita Y, Kobayashi K, Watanabe K, Ozawa Y, Koike M, Asou Y, Takaku T, Kaneko K, Shimizu T
    • Journal Title

      J Bone Miner Res

      Volume: 28 Pages: 2368-80

    • Data Source
      KAKENHI-PROJECT-24791569
  • [Journal Article] 骨細胞における抗酸化酵素Sod2の骨リモデリング制御機構2013

    • Author(s)
      小林 慶司, 野尻 英俊, 齋田 良知, 森川 大智, 小池 正人, 麻生 義則, 金子 和夫, 清水 孝彦
    • Journal Title

      日本整形外科学会雑誌

      Volume: 87巻8号

    • Data Source
      KAKENHI-PROJECT-24791568
  • [Journal Article] Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading.2013

    • Author(s)
      Morikawa D, Nojiri H, Saita Y, Kobayashi K, Watanabe K, Ozawa Y, Koike M, Asou Y, Takaku T, Kaneko K, Shimizu T.
    • Journal Title

      J Bone Miner Res

      Volume: november 28(11) Issue: 11 Pages: 2368-80

    • DOI

      10.1002/jbmr.1981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791568
  • [Journal Article] 骨細胞特異的Sod2欠損マウスにおける骨リモデリング制御機構の解析2013

    • Author(s)
      小林 慶司, 野尻 英俊, 齋田 良知, 森川 大智, 小池 正人, 麻生 義則, 金子 和夫, 清水 孝彦
    • Journal Title

      日本骨代謝学会学術集会プログラム抄録集

      Volume: 31 Pages: 77-77

    • Data Source
      KAKENHI-PROJECT-24791568
  • [Journal Article] CuZn-SOD 欠損は低骨代謝回転型骨量減少と加齢性コラーゲン架橋変化を引き起こし骨脆弱化する2012

    • Author(s)
      清水 孝彦, 野尻 英俊
    • Journal Title

      Biomedical Research on Trace Elements

      Volume: 23巻1号 Pages: 1-5

    • NAID

      10030755992

    • Data Source
      KAKENHI-PROJECT-24791568
  • [Journal Article] スーパーオキサイドディスムターゼ1(SOD1)による骨代謝制御機構の解析2012

    • Author(s)
      野尻 英俊, 斎田 良知
    • Journal Title

      整形外科

      Volume: 63巻11号 Pages: 1168-1168

    • Data Source
      KAKENHI-PROJECT-24791568
  • [Journal Article] Cytoplasmic superoxide causes bone fragility owing to low-turnover osteoporosis and impaired collagen cross-linking2011

    • Author(s)
      Nojiri, Saita, et al
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: Volume 26 Pages: 2682-2694

    • NAID

      40019538687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791416
  • [Journal Article] Cytoplasmic superoxide causes bone fragility owing to low-tumover osteoporosis and impaired collagen cross-linking2011

    • Author(s)
      Nojiri, Saita, et al
    • Journal Title

      Journal of Bone and Mineral Research, pages 2682-2694, November 2011

      Volume: Volume 26,Issue 11 Pages: 2682-2694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791416
  • [Journal Article] Model mice for tissue-specific deletion of the manganese superoxide dismutase gene.2010

    • Author(s)
      Takahiko Shimizu, Hidetoshi Nojiri, Satoru Kawakami, Satoshi Uchiyama, Takuji Shirasawa.
    • Journal Title

      Geriatr Gerontol Int 10

    • NAID

      10027273145

    • Data Source
      KAKENHI-PROJECT-21791415
  • [Journal Article] Oxidative stress in skeletal muscle causes severe disturbance of exercise activity without muscle atrophy.2010

    • Author(s)
      Kuwahara H, Horie T, Ishikawa S, Tsuda C, Kawakami S, Noda Y, Kaneko T, Tahara S, Tachibana T, Okabe M, Melki J, Takano R, Toda T, Morikawa D, Nojiri H, Kurosawa H, Shirasawa T, Shimizu T.
    • Journal Title

      Free Radic Biol Med 48

      Pages: 1252-1262

    • Data Source
      KAKENHI-PROJECT-21791415
  • [Patent] 関節症若しくは関節炎の、治療剤又は予防剤2015

    • Inventor(s)
      野尻英俊
    • Industrial Property Rights Holder
      野尻英俊
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-05-18
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] 女性腰椎変性疾患患者における握力低下と傍脊柱筋の酸化ストレスとの関連2024

    • Author(s)
      高橋良介, 野尻英俊, 藤原俊之, 石島旨章
    • Organizer
      第97回日本整形外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K09409
  • [Presentation] 女性腰椎変性疾患患者における握力低下と傍脊柱筋の酸化ストレスとの関連2023

    • Author(s)
      高橋良介, 野尻英俊, 藤原俊之, 石島旨章
    • Organizer
      第38回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K09409
  • [Presentation] 末期膝OA患者の関節軟骨および滑膜におけるSOD活性とスーパーオキシドの挙動.2017

    • Author(s)
      小池 正人, 野尻 英俊, 幡野 佐巳依, 宮川 慶, 澤 満美子, 岩瀬 嘉志, 黒澤 尚, 金子 和夫
    • Organizer
      第90回日本整形外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10942
  • [Presentation] 末期膝OAにおけるSOD活性とスーパーオキシドの動向.2017

    • Author(s)
      小池正人, 野尻英俊, 幡野佐巳依, 宮川 慶, 澤 満美子, 岩瀬 嘉志, 黒澤 尚, 金子 和夫
    • Organizer
      第17回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-17K10942
  • [Presentation] ロコモティブシンドロームと酸化ストレスの関連性~ロコモ初診時における横断研究2017

    • Author(s)
      幡野佐巳依, 野尻英俊, 小池正人, 宮川 慶, 澤 満美子, 岩瀬 嘉志, 黒澤 尚, 金子 和夫
    • Organizer
      第17回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-17K10942
  • [Presentation] Mitochondrial SOD in osteocytes plays a pivotal role in maintaining bone metabolism in mice.2017

    • Author(s)
      Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri.
    • Organizer
      Asian Society of Aging Research Symposium 2017
    • Place of Presentation
      札幌グランドホテル(北海道札幌市)
    • Year and Date
      2017-03-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Presentation] The relationship between locomotive syndrome and oxidative stress; Cross-sectional study of 66 patients with locomotive symptoms.2017

    • Author(s)
      Banno S, Nojiri H, Koike M, Miyagawa K, Iwase Y, Kurosawa H, Kaneko K
    • Organizer
      Cell Symposia, Gothenburg, Sweden, May 21-23, 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10942
  • [Presentation] Imbalance between low sod activity and excessive superoxide occurs in end-stage OA cartilage and synovium.2017

    • Author(s)
      Koike M, Nojiri H, Banno S, Miyagawa K, Sawa M, Iwase Y, Kurosawa H, Kaneko K
    • Organizer
      OARSI
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10942
  • [Presentation] 末期変形性関節症の軟骨細胞内スーパーオキシドは顕著に増加する.2016

    • Author(s)
      野尻英俊
    • Organizer
      第16回日本抗加齢医学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] 加齢に伴う運動器の機能低下と酸化ストレス2016

    • Author(s)
      野尻英俊
    • Organizer
      第11回ファンクショナルフード学会
    • Place of Presentation
      東京
    • Year and Date
      2016-08-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] Apple polyphenols protect cartilage degeneration through modulating mitochondrial function in mice.2016

    • Author(s)
      Isao Masuda, Masato Koike, Yusuke Ozawa, Kenji Watanabe, Shohei Nakashima, Hiroshi Sugiyama, Tomomasa Kanda Hidetoshi Nojiri, Takahiko Shimizu.
    • Organizer
      2016 World Congress of Osteoarthritis Research Society International
    • Place of Presentation
      Amsterdam(オランダ)
    • Year and Date
      2016-04-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Presentation] Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration.2016

    • Author(s)
      Takahiko Shimizu, Masato Koike, Hidetoshi Nojiri.
    • Organizer
      Cell symposia Aging & Metabolism
    • Place of Presentation
      Melia Stiges(スペイン)
    • Year and Date
      2016-07-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Presentation] Mitochondrial superoxide regulation in chondrocytes suppresses mechanical overloading-induced cartilage degeneration.2016

    • Author(s)
      Masato Koike, Hidetoshi Nojiri, Haruka Kaneko, Daichi Morikawa, Keiji Kobayashi, Yoshitomo Saita, Kazuo Kaneko, Takahiko Shimizu.
    • Organizer
      Orthopaedic Research Society (ORS) Annual Meeting 2016
    • Place of Presentation
      Orlando (USA)
    • Year and Date
      2016-03-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Presentation] 加齢に伴う運動器の機能低下と酸化ストレスの関係2016

    • Author(s)
      野尻英俊
    • Organizer
      第44回日本関節病学会
    • Place of Presentation
      別府
    • Year and Date
      2016-11-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] Mn-SOD loss in osteocytes causes age-related bone loss associated with impairment of bone remodeling.2015

    • Author(s)
      Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri
    • Organizer
      The 10th IAGG (International Association of Gerontology and Geriatrics) Asia/Oceania 2015 Congress
    • Place of Presentation
      Chiang Mai (Thailand)
    • Year and Date
      2015-10-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Presentation] SOD2 loss in osteocytes perturbs canalicular networks associated with impairment of bone remodeling in age-related osteoporosis.2015

    • Author(s)
      Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri, Koutaro Yokote
    • Organizer
      Biology of Ageing Conference
    • Place of Presentation
      Singapore
    • Year and Date
      2015-10-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Presentation] Contribution of mitochondrial superoxide and SOD2 imbalance to the locomotive syndrome.2015

    • Author(s)
      Hidetoshi Nojiri, Daichi Morikawa, Keiji Kobayashi, Masato Koike, Yoshitomo Saita, Kazuo Kaneko, Takahiko Shimizu
    • Organizer
      The 2nd International Academy of Sportology
    • Place of Presentation
      順天堂大学(東京都文京区)
    • Year and Date
      2015-09-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462283
  • [Presentation] Chondrocyte-specific Deletion of Sod2 Exacerbates Cartilage Degeneration Associated with Low Mitochondrial Membrane Potential in Mice2014

    • Author(s)
      Masato Koike, Nojiri Hidetoshi, Yoshitomo Saita et al.
    • Organizer
      ASBMR 2014 Annual Meeting
    • Place of Presentation
      Houston, Texas, USA
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] Osteocyte Specific Deletion of Superoxide Dismutase2 Induces Osteocyte Loss Resulting in Bone Loss Associated with Impairment of Bone Remodeling2013

    • Author(s)
      Keiji Kobayashi, Hidetoshi Nojiri, Yoshitomo Saita, Daichi Morikawa, Masato Koike, Yusuke Ozawa, Yoshinori Asou, Kazuo Kaneko, Takahiko Shimizu,
    • Organizer
      2013 ASBMR Annual Meeting Abstracts
    • Place of Presentation
      Baltimore, USA
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] 骨細胞特異的Sod2欠損マウスにおける骨リモデリング制御機構の解析2013

    • Author(s)
      小林 慶司, 野尻 英俊, 齋田 良知, 森川 大智, 小池 正人, 麻生 義則, 金子 和夫, 清水 孝彦
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] 細胞質活性酸素とSOD1は機械的刺激応答に伴う骨量変化を制御する2013

    • Author(s)
      清水 孝彦, 森川 大智, 野尻 英俊, 斎田 良知, 渡辺 憲史, 麻生 義則, 金子 和夫
    • Organizer
      日本基礎老化学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] 骨細胞における抗酸化酵素Sod2の骨リモデリング制御機構2013

    • Author(s)
      小林 慶司, 野尻 英俊, 齋田 良知, 森川 大智, 小池 正人, 麻生 義則, 金子 和夫, 清水 孝彦
    • Organizer
      日本整形外科学会基礎学術集会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] スーパーオキサイドディスムターゼ1(SOD1)欠損は低代謝回転型骨量減少と加齢性コラーゲン架橋変化を引き起こし骨脆弱化する2012

    • Author(s)
      野尻 英俊, 斎田 良知, 森川 大智, 小林 慶司, 宮崎 剛, 斎藤 充, 丸毛 啓史, 金子 和夫, 清水 孝彦
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      新宿
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] 細胞質酸化ストレスは低代謝型骨量減少を引き起こす2012

    • Author(s)
      森川 大智, 野尻 英俊, 斎田 良知, 津田 千鶴, 斎藤 充, 宮崎 剛, 金子 和夫, 清水 孝彦
    • Organizer
      日本生化学会大会・日本分子生物学会年会合同大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] メカニカルストレス応答における酸化ストレスと抗酸化酵素の解析2012

    • Author(s)
      森川 大智, 野尻 英俊, 齋田 良知, 小林 慶司, 渡辺 憲史, 麻生 義則, 金子 和夫, 清水 孝彦
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      新宿
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] スーパーオキサイドディスムターゼ1(SOD1)欠損は低代謝回転型骨量減少と加齢性コラーゲン架橋変化を引き起こし骨脆弱化する2011

    • Author(s)
      野尻英俊
    • Organizer
      日本骨代謝学会学術集会
    • Place of Presentation
      新大阪
    • Data Source
      KAKENHI-PROJECT-21791416
  • [Presentation] Vitamin C Administration Markedly Ameliorates Bone Loss by Restoring the Osteoblastic Viability in Sod1-Deficient Mice2011

    • Author(s)
      Hidetoshi Nojiri
    • Organizer
      第33回アメリカ骨代謝学会
    • Place of Presentation
      アメリカ・サンディエゴ
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PROJECT-21791416
  • [Presentation] Analysis of oxidative stress and antioxidant enzymes in mechanical stress response2011

    • Author(s)
      Morikawa D, Saita Y, Nojiri H, Kobayashi K, Watanabe K, Asou Y, Kaneko K, Shimizu T
    • Organizer
      第29回日本骨代謝学会
    • Place of Presentation
      Gold Coast, Australia
    • Data Source
      KAKENHI-PROJECT-24791569
  • [Presentation] メカニカルストレス応答における酸化ストレスと抗酸化酵素の解析2011

    • Author(s)
      森川大智, 野尻英俊, 斎田良知, 小林慶司, 渡辺憲史, 麻生義則, 金子和夫, 清水孝彦
    • Organizer
      第29回日本骨代謝学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24791569
  • [Presentation] 筋細胞におけるミトコンドリア内酸化ストレスは呼吸鎖を障害し著しい運動能力の低下をきたす2010

    • Author(s)
      野尻英俊, 桑原宏朋, 森川大智, 斎田良知, 金子和夫, 清水孝彦
    • Organizer
      第25回日本整形外科学会基礎学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21791415
  • [Presentation] Copper/zinc superoxide dismutase deficiency causes low turnover osteopenia via osteoblastic dysfunction2009

    • Author(s)
      野尻英俊
    • Organizer
      第31回アメリカ骨代謝学会
    • Place of Presentation
      アメリカ・デンバー
    • Year and Date
      2009-09-11
    • Data Source
      KAKENHI-PROJECT-21791416
  • [Presentation] Chondrocyte-specific Deletion of Sod2 Exacerbates Cartilage Degeneration Associated with Low Mitochondrial Membrane Potential in Mice.

    • Author(s)
      Koike M, Nojiri H
    • Organizer
      American Society for Bone and Mineral Research (ASBMR) 2014 Annual Meeting
    • Place of Presentation
      Houston
    • Year and Date
      2014-09-12 – 2014-09-15
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] 骨細胞における酸化ストレスは骨リモデリングバランスの破綻をもたらす

    • Author(s)
      小林 慶司, 野尻 英俊, 齋田 良知, 森川 大智, 小池 正人, 小澤 裕介, 麻生 義則, 金子 和夫, 清水 孝彦
    • Organizer
      日本整形外科学会
    • Place of Presentation
      神戸国際展示場
    • Year and Date
      2014-05-22 – 2014-05-25
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] Sod2 deficiency in chondrocytes accelerates age-related osteoarthritis in mice.

    • Author(s)
      Koike M, Nojiri H
    • Organizer
      2014 Osteoarthritis Research Society International (OARSI) world congress 2014
    • Place of Presentation
      Paris
    • Year and Date
      2014-04-24 – 2014-04-27
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] OA発症メカニズム

    • Author(s)
      小池正人、野尻英俊
    • Organizer
      第29回日本整形外科基礎学術集会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] Chondrocyte-specific deletion of Sod2 exacerbates age-related cartilage degeneration in mice.

    • Author(s)
      Koike M, Nojiri H
    • Organizer
      Australia and New Zealand Bone & Mineral Society (ANZBMS) 24th Annual Scientific Meeting
    • Place of Presentation
      Queenstown
    • Year and Date
      2014-09-07 – 2014-09-10
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] 関節軟骨におけるSod2欠損は加齢性軟骨変性を助長する

    • Author(s)
      小池正人、野尻英俊
    • Organizer
      第32回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-24 – 2014-07-26
    • Data Source
      KAKENHI-PROJECT-26462319
  • [Presentation] SOD2 deficiency in chondrocytes accelerates age-related osteoarthritis in mice

    • Author(s)
      M. Koike, H. Nojiri, Y. Ozawa, K. Watanabe, I. Masuda, Y. Muramatsu, H. Kaneko, D. Morikawa, K. Kobayashi, Y. Saita, T. Sasho, T. Shirasawa, K. Yokote, K. Kaneko, T. Shimizu
    • Organizer
      Osteoarthritis and Cartilage 2014 World Congress
    • Place of Presentation
      Paris, France
    • Year and Date
      2014-04-24 – 2014-04-27
    • Data Source
      KAKENHI-PROJECT-24791568
  • [Presentation] Superoxide dismutase 2 deficiency in osteocytes causes age-related bone loss associated with impairment of bone remodeling.

    • Author(s)
      Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri.
    • Organizer
      The Japan-Korea Joint Symposium 2014
    • Place of Presentation
      Jeju (Korea)
    • Year and Date
      2014-06-20 – 2014-06-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26462283
  • 1.  SHIMIZU Takahiko (40301791)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 24 results
  • 2.  SAITA Yoshitomo (00534885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 3.  ASOU Yoshinori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  丸山 祐一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  糸魚川 善昭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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