NOJIRI Hidetoshi 野尻英俊

… Alternative Names

野尻英俊ノジリヒデトシ

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Researcher Number	10317456
Affiliation (Current)	2025: 順天堂大学, 医学部, 先任准教授
Affiliation (based on the past Project Information) *help	2025: 順天堂大学, 医学部, 先任准教授 2023: 順天堂大学, 医学部, 先任准教授 2022: 順天堂大学, 医学部, 准教授 2014 – 2020: 順天堂大学, 医学部, 准教授 2014: 順天堂大学, 整形外科, 助教 2009 – 2013: Juntendo University, 医学部, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 酸化ストレス / スーパーオキシド / 変性 / SOD / 加齢 / 脊柱管狭窄 / 黄色靭帯 / 脊柱後弯症 / 女性 / 筋力低下 … More / 傍脊柱筋 / 老化 / SOD活性 / サプリメント / 健康食品 / GliSODin / 運動器 / Sod2 / メカニカルストレス / 変形性関節症 / 軟骨 / Sod1 / 廃用性骨萎縮 / SOD1 / 骨萎縮 / 廃用 / 骨・軟骨代謝学 / 運動能力 / モデルマウス / 走行能力 / ATP / ミトコンドリア / 骨格筋 / Mn-SOD … More Except Principal Investigator 酸化ストレス / 骨粗鬆症 / 老化 / 骨格筋 / SOD / 骨 / 骨代謝 / 加齢 / 破骨細胞 / 骨芽細胞 / Mn-SOD / 骨細胞 / 活性酸素 / CuZn-SOD / モデルマウス / 遺伝子 / スーパーオキサイドディスムターゼ(SOD) Less

Pathological Significance of Oxidative Stress in Ligamentum Flavum Alterations of Spinal Canal StenosisPrincipal Investigator
- Principal Investigator
  
  野尻英俊
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
脊柱後弯症における傍脊柱筋内酸化ストレスの病理的意義の解明Principal Investigator
- Principal Investigator
  
  野尻英俊
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Verification of the usefulness of oxidative stress regulation for functional decline associated with age-related degeneration of locomotive organsPrincipal Investigator
- Principal Investigator
  
  Nojiri Hidetoshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
Pathological role of mitochondrial oxidative stress in cartilage degenerationPrincipal Investigator
- Principal Investigator
  
  Nojiri Hidetoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
Oxidative stress in bone regulates skeletal homeostasis in mice
- Principal Investigator
  
  Shimizu Takahiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University
The role of oxidative stress in the maintenance of bone metabolism
- Principal Investigator
  
  SAITA Yoshitomo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
Analysis of pathological role of cytoplasmic oxidative stress in disuse bone atrophy.Principal Investigator
- Principal Investigator
  
  NOJIRI Hidetoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
Molecular analysis for oxidative stress-induced senescent motor weaknessPrincipal Investigator
- Principal Investigator
  
  NOJIRI Hidetoshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
The development and analyses of the mouse model of age-related osteoporosis.
- Principal Investigator
  
  SAITA Yoshitomo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University

[Book] Systems Biology of Free Radicals and Antioxidants2014
- Author(s)
  Shimizu T, Nojiri H, et al.
- Publisher
  Springer-Verlag Berlin Heidelberg
- Data Source
  KAKENHI-PROJECT-26462319
[Book] Aging: Oxidative Stress and Dietary Antioxidants2014
- Author(s)
  Shibuya S, Nojiri H, et al.
- Publisher
  Elsevier Inc.
- Data Source
  KAKENHI-PROJECT-26462319
[Journal Article] Decreased grip strength is associated with paraspinal muscular oxidative stress in female lumbar degenerative disease patients2024
- Author(s)
  Takahashi Ryosuke、Nojiri Hidetoshi、Ohara Yukoh、Fujiwara Toshiyuki、Ishijima Muneaki
- Journal Title
  
  Journal of Orthopaedic Research
  
  Volume: - Issue: 10 Pages: 2287-2295
- DOI
  10.1002/jor.25863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09409
[Journal Article] Association of Superoxide‐Induced Oxidative Stress With Rotator Cuff Tears in Human Patients2019
- Author(s)
  Yoshida Keiichi、Itoigawa Yoshiaki、Wada Tomoki、Maruyama Yuichiro、Nojiri Hidetoshi、Kawasaki Takayuki、Kaneko Kazuo
- Journal Title
  
  Journal of Orthopaedic Research
  
  Volume: 38 Issue: 1 Pages: 212-218
- DOI
  10.1002/jor.24472
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09081, KAKENHI-PROJECT-18K18371, KAKENHI-PROJECT-17K10942
[Journal Article] Antioxidant treatment with vitamin C attenuated rotator cuff degeneration caused by oxidative stress in Sod1-deficient mice.2018
- Author(s)
  30.Morikawa D, Nojiri H, Itoigawa Y, Ozawa Y, Kaneko K, Shimizu T.
- Journal Title
  
  JSES Open Access
  
  Volume: ２ Issue: 1 Pages: 91-96
- DOI
  10.1016/j.jses.2017.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10942
[Journal Article] Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage2018
- Author(s)
  Koike M, Nojiri H, Kanazawa H, Yamaguchi H, Miyagawa K, Nagura N, Banno S, Iwase Y, Kurosawa H, Kaneko K.
- Journal Title
  
  PLoS One
  
  Volume: １３ Issue: 9 Pages: e0203944-e0203944
- DOI
  10.1371/journal.pone.0203944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10942, KAKENHI-PROJECT-17K16704
[Journal Article] Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes.2018
- Author(s)
  Masuda I, Koike M, Nakashima S, Mizutani Y, Ozawa Y, Watanabe K, Sawada Y, Sugiyama H, Sugimoto A, Nojiri H, Sashihara K, Yokote K, Shimizu T
- Journal Title
  
  Sci Rep.
  
  Volume: ８ Issue: 1 Pages: 7229-7229
- DOI
  10.1038/s41598-018-25348-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10942, KAKENHI-PROJECT-17H01558
[Journal Article] Brain-specific superoxide dismutase 2 deficiency causes perinatal death with spongiform encephalopathy in mice.2015
- Author(s)
  Izuo, N., Nojiri, H., Uchiyama, S., Noda, Y., Kawakami, S., Kojima, S., Sasaki, T., Shirasawa, T., Shimizu, T.
- Journal Title
  
  Oxid. Med. Cell. Longev
  
  Volume: 2015 Pages: 238914-238914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462283
[Journal Article] Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration2015
- Author(s)
  Koike, M., Nojiri, H., Ozawa, Y., Watanabe, K., Muramatsu, Y., Kaneko, H., Morikawa, D., Kobayashi, K., Saita, Y., Sasho, T., Shirasawa, T., Yokote, K., Kaneko, K., Shimizu, T.
- Journal Title
  
  Sci. Rep.
  
  Volume: 5 Issue: 1 Pages: 11722-11722
- DOI
  10.1038/srep11722
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-26462319, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
[Journal Article] Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis.2015
- Author(s)
  Kobayashi K1, Nojiri H2, Saita Y2, Morikawa D1, Ozawa Y3, Watanabe K3, Koike M1, Asou Y4, Shirasawa T5, Yokote K6, Kaneko K2, Shimizu T3.
- Journal Title
  
  Scientific Reports
  
  Volume: Mar 16;5 Issue: 1 Pages: 9148-9148
- DOI
  10.1038/srep09148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791568, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-26462319, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
[Journal Article] Brain-specific superoxide dismutase 2 deficiency causes perinatal death with spongiform encephalopathy in mice.2015
- Author(s)
  Izuo, N., Nojiri, H., Uchiyama, S., Noda, Y., Kawakami, S., Kojima, S., Sasaki, T., Shirasawa, T., Shimizu, T.
- Journal Title
  
  Oxid. Med. Cell. Longev.
  
  Volume: 2015 Pages: 238914-238914
- DOI
  10.1155/2015/238914
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-26462319, KAKENHI-PROJECT-15K19279
[Journal Article] Superoxide dismutase 1 loss disturbs intracellular redox signaling, resulting in global age-related pathological changes.2014
- Author(s)
  Watanabe, K., Shibuya, S., Ozawa, Y., Nojiri, H., Izuo, N., Yokote, K., and Shimizu, T.
- Journal Title
  
  BioMed. Res. Int.
  
  Volume: 2014 Pages: 140165-140165
- DOI
  10.1155/2014/140165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462283
[Journal Article] Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading2013
- Author(s)
  Morikawa D, Nojiri H, Saita Y, Kobayashi K, Watanabe K, Ozawa Y, Koike M, Asou Y, Takaku T, Kaneko K, Shimizu T
- Journal Title
  
  J Bone Miner Res
  
  Volume: 28 Pages: 2368-80
- Data Source
  KAKENHI-PROJECT-24791569
[Journal Article] 骨細胞における抗酸化酵素Sod2の骨リモデリング制御機構2013
- Author(s)
  小林慶司, 野尻英俊, 齋田良知, 森川大智, 小池正人, 麻生義則, 金子和夫, 清水孝彦
- Journal Title
  
  日本整形外科学会雑誌
  
  Volume: 87巻8号
- Data Source
  KAKENHI-PROJECT-24791568
[Journal Article] Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading.2013
- Author(s)
  Morikawa D, Nojiri H, Saita Y, Kobayashi K, Watanabe K, Ozawa Y, Koike M, Asou Y, Takaku T, Kaneko K, Shimizu T.
- Journal Title
  
  J Bone Miner Res
  
  Volume: november 28(11) Issue: 11 Pages: 2368-80
- DOI
  10.1002/jbmr.1981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791568
[Journal Article] 骨細胞特異的Sod2欠損マウスにおける骨リモデリング制御機構の解析2013
- Author(s)
  小林慶司, 野尻英俊, 齋田良知, 森川大智, 小池正人, 麻生義則, 金子和夫, 清水孝彦
- Journal Title
  
  日本骨代謝学会学術集会プログラム抄録集
  
  Volume: 31 Pages: 77-77
- Data Source
  KAKENHI-PROJECT-24791568
[Journal Article] CuZn-SOD 欠損は低骨代謝回転型骨量減少と加齢性コラーゲン架橋変化を引き起こし骨脆弱化する2012
- Author(s)
  清水孝彦, 野尻英俊
- Journal Title
  
  Biomedical Research on Trace Elements
  
  Volume: 23巻1号 Pages: 1-5
- NAID
  10030755992
- Data Source
  KAKENHI-PROJECT-24791568
[Journal Article] スーパーオキサイドディスムターゼ1(SOD1)による骨代謝制御機構の解析2012
- Author(s)
  野尻英俊, 斎田良知
- Journal Title
  
  整形外科
  
  Volume: 63巻11号 Pages: 1168-1168
- Data Source
  KAKENHI-PROJECT-24791568
[Journal Article] Cytoplasmic superoxide causes bone fragility owing to low-turnover osteoporosis and impaired collagen cross-linking2011
- Author(s)
  Nojiri, Saita, et al
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: Volume 26 Pages: 2682-2694
- NAID
  40019538687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791416
[Journal Article] Cytoplasmic superoxide causes bone fragility owing to low-tumover osteoporosis and impaired collagen cross-linking2011
- Author(s)
  Nojiri, Saita, et al
- Journal Title
  
  Journal of Bone and Mineral Research, pages 2682-2694, November 2011
  
  Volume: Volume 26,Issue 11 Pages: 2682-2694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791416
[Journal Article] Model mice for tissue-specific deletion of the manganese superoxide dismutase gene.2010
- Author(s)
  Takahiko Shimizu, Hidetoshi Nojiri, Satoru Kawakami, Satoshi Uchiyama, Takuji Shirasawa.
- Journal Title
  
  Geriatr Gerontol Int 10
- NAID
  10027273145
- Data Source
  KAKENHI-PROJECT-21791415
[Journal Article] Oxidative stress in skeletal muscle causes severe disturbance of exercise activity without muscle atrophy.2010
- Author(s)
  Kuwahara H, Horie T, Ishikawa S, Tsuda C, Kawakami S, Noda Y, Kaneko T, Tahara S, Tachibana T, Okabe M, Melki J, Takano R, Toda T, Morikawa D, Nojiri H, Kurosawa H, Shirasawa T, Shimizu T.
- Journal Title
  
  Free Radic Biol Med 48
  
  Pages: 1252-1262
- Data Source
  KAKENHI-PROJECT-21791415
[Patent] 関節症若しくは関節炎の、治療剤又は予防剤2015
- Inventor(s)
  野尻英俊
- Industrial Property Rights Holder
  野尻英俊
- Industrial Property Rights Type
  特許
- Filing Date
  2015-05-18
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] 女性腰椎変性疾患患者における握力低下と傍脊柱筋の酸化ストレスとの関連2024
- Author(s)
  高橋良介, 野尻英俊, 藤原俊之, 石島旨章
- Organizer
  第９７回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09409
[Presentation] 女性腰椎変性疾患患者における握力低下と傍脊柱筋の酸化ストレスとの関連2023
- Author(s)
  高橋良介, 野尻英俊, 藤原俊之, 石島旨章
- Organizer
  第３８回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-22K09409
[Presentation] 末期膝OA患者の関節軟骨および滑膜におけるSOD活性とスーパーオキシドの挙動.2017
- Author(s)
  小池正人, 野尻英俊, 幡野佐巳依, 宮川慶, 澤満美子, 岩瀬嘉志, 黒澤尚, 金子和夫
- Organizer
  第90回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10942
[Presentation] 末期膝ＯＡにおけるＳＯＤ活性とスーパーオキシドの動向.2017
- Author(s)
  小池正人, 野尻英俊, 幡野佐巳依, 宮川慶, 澤満美子, 岩瀬嘉志, 黒澤尚, 金子和夫
- Organizer
  第１７回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K10942
[Presentation] ロコモティブシンドロームと酸化ストレスの関連性～ロコモ初診時における横断研究2017
- Author(s)
  幡野佐巳依, 野尻英俊, 小池正人, 宮川慶, 澤満美子, 岩瀬嘉志, 黒澤尚, 金子和夫
- Organizer
  第１７回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K10942
[Presentation] Mitochondrial SOD in osteocytes plays a pivotal role in maintaining bone metabolism in mice.2017
- Author(s)
  Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri.
- Organizer
  Asian Society of Aging Research Symposium 2017
- Place of Presentation
  札幌グランドホテル（北海道札幌市）
- Year and Date
  2017-03-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462283
[Presentation] The relationship between locomotive syndrome and oxidative stress; Cross-sectional study of 66 patients with locomotive symptoms.2017
- Author(s)
  Banno S, Nojiri H, Koike M, Miyagawa K, Iwase Y, Kurosawa H, Kaneko K
- Organizer
  Cell Symposia, Gothenburg, Sweden, May 21-23, 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10942
[Presentation] Imbalance between low sod activity and excessive superoxide occurs in end-stage OA cartilage and synovium.2017
- Author(s)
  Koike M, Nojiri H, Banno S, Miyagawa K, Sawa M, Iwase Y, Kurosawa H, Kaneko K
- Organizer
  OARSI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10942
[Presentation] 末期変形性関節症の軟骨細胞内スーパーオキシドは顕著に増加する.2016
- Author(s)
  野尻英俊
- Organizer
  第１６回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] 加齢に伴う運動器の機能低下と酸化ストレス2016
- Author(s)
  野尻英俊
- Organizer
  第１１回ファンクショナルフード学会
- Place of Presentation
  東京
- Year and Date
  2016-08-26
- Invited
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] Apple polyphenols protect cartilage degeneration through modulating mitochondrial function in mice.2016
- Author(s)
  Isao Masuda, Masato Koike, Yusuke Ozawa, Kenji Watanabe, Shohei Nakashima, Hiroshi Sugiyama, Tomomasa Kanda Hidetoshi Nojiri, Takahiko Shimizu.
- Organizer
  2016 World Congress of Osteoarthritis Research Society International
- Place of Presentation
  Amsterdam（オランダ）
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462283
[Presentation] Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration.2016
- Author(s)
  Takahiko Shimizu, Masato Koike, Hidetoshi Nojiri.
- Organizer
  Cell symposia Aging & Metabolism
- Place of Presentation
  Melia Stiges（スペイン）
- Year and Date
  2016-07-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462283
[Presentation] Mitochondrial superoxide regulation in chondrocytes suppresses mechanical overloading-induced cartilage degeneration.2016
- Author(s)
  Masato Koike, Hidetoshi Nojiri, Haruka Kaneko, Daichi Morikawa, Keiji Kobayashi, Yoshitomo Saita, Kazuo Kaneko, Takahiko Shimizu.
- Organizer
  Orthopaedic Research Society (ORS) Annual Meeting 2016
- Place of Presentation
  Orlando (USA)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462283
[Presentation] 加齢に伴う運動器の機能低下と酸化ストレスの関係2016
- Author(s)
  野尻英俊
- Organizer
  第４４回日本関節病学会
- Place of Presentation
  別府
- Year and Date
  2016-11-12
- Invited
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] Mn-SOD loss in osteocytes causes age-related bone loss associated with impairment of bone remodeling.2015
- Author(s)
  Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri
- Organizer
  The 10th IAGG (International Association of Gerontology and Geriatrics) Asia/Oceania 2015 Congress
- Place of Presentation
  Chiang Mai (Thailand)
- Year and Date
  2015-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462283
[Presentation] SOD2 loss in osteocytes perturbs canalicular networks associated with impairment of bone remodeling in age-related osteoporosis.2015
- Author(s)
  Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri, Koutaro Yokote
- Organizer
  Biology of Ageing Conference
- Place of Presentation
  Singapore
- Year and Date
  2015-10-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462283
[Presentation] Contribution of mitochondrial superoxide and SOD2 imbalance to the locomotive syndrome.2015
- Author(s)
  Hidetoshi Nojiri, Daichi Morikawa, Keiji Kobayashi, Masato Koike, Yoshitomo Saita, Kazuo Kaneko, Takahiko Shimizu
- Organizer
  The 2nd International Academy of Sportology
- Place of Presentation
  順天堂大学（東京都文京区）
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462283
[Presentation] Chondrocyte-specific Deletion of Sod2 Exacerbates Cartilage Degeneration Associated with Low Mitochondrial Membrane Potential in Mice2014
- Author(s)
  Masato Koike, Nojiri Hidetoshi, Yoshitomo Saita et al.
- Organizer
  ASBMR 2014 Annual Meeting
- Place of Presentation
  Houston, Texas, USA
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] Osteocyte Specific Deletion of Superoxide Dismutase2 Induces Osteocyte Loss Resulting in Bone Loss Associated with Impairment of Bone Remodeling2013
- Author(s)
  Keiji Kobayashi, Hidetoshi Nojiri, Yoshitomo Saita, Daichi Morikawa, Masato Koike, Yusuke Ozawa, Yoshinori Asou, Kazuo Kaneko, Takahiko Shimizu,
- Organizer
  2013 ASBMR Annual Meeting Abstracts
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] 骨細胞特異的Sod2欠損マウスにおける骨リモデリング制御機構の解析2013
- Author(s)
  小林慶司, 野尻英俊, 齋田良知, 森川大智, 小池正人, 麻生義則, 金子和夫, 清水孝彦
- Organizer
  日本骨代謝学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] 細胞質活性酸素とSOD1は機械的刺激応答に伴う骨量変化を制御する2013
- Author(s)
  清水孝彦, 森川大智, 野尻英俊, 斎田良知, 渡辺憲史, 麻生義則, 金子和夫
- Organizer
  日本基礎老化学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] 骨細胞における抗酸化酵素Sod2の骨リモデリング制御機構2013
- Author(s)
  小林慶司, 野尻英俊, 齋田良知, 森川大智, 小池正人, 麻生義則, 金子和夫, 清水孝彦
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] スーパーオキサイドディスムターゼ1(SOD1)欠損は低代謝回転型骨量減少と加齢性コラーゲン架橋変化を引き起こし骨脆弱化する2012
- Author(s)
  野尻英俊, 斎田良知, 森川大智, 小林慶司, 宮崎剛, 斎藤充, 丸毛啓史, 金子和夫, 清水孝彦
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  新宿
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] 細胞質酸化ストレスは低代謝型骨量減少を引き起こす2012
- Author(s)
  森川大智, 野尻英俊, 斎田良知, 津田千鶴, 斎藤充, 宮崎剛, 金子和夫, 清水孝彦
- Organizer
  日本生化学会大会・日本分子生物学会年会合同大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] メカニカルストレス応答における酸化ストレスと抗酸化酵素の解析2012
- Author(s)
  森川大智, 野尻英俊, 齋田良知, 小林慶司, 渡辺憲史, 麻生義則, 金子和夫, 清水孝彦
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  新宿
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] スーパーオキサイドディスムターゼ1(SOD1)欠損は低代謝回転型骨量減少と加齢性コラーゲン架橋変化を引き起こし骨脆弱化する2011
- Author(s)
  野尻英俊
- Organizer
  日本骨代謝学会学術集会
- Place of Presentation
  新大阪
- Data Source
  KAKENHI-PROJECT-21791416
[Presentation] Vitamin C Administration Markedly Ameliorates Bone Loss by Restoring the Osteoblastic Viability in Sod1-Deficient Mice2011
- Author(s)
  Hidetoshi Nojiri
- Organizer
  第33回アメリカ骨代謝学会
- Place of Presentation
  アメリカ・サンディエゴ
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-21791416
[Presentation] Analysis of oxidative stress and antioxidant enzymes in mechanical stress response2011
- Author(s)
  Morikawa D, Saita Y, Nojiri H, Kobayashi K, Watanabe K, Asou Y, Kaneko K, Shimizu T
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  Gold Coast, Australia
- Data Source
  KAKENHI-PROJECT-24791569
[Presentation] メカニカルストレス応答における酸化ストレスと抗酸化酵素の解析2011
- Author(s)
  森川大智, 野尻英俊, 斎田良知, 小林慶司, 渡辺憲史, 麻生義則, 金子和夫, 清水孝彦
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24791569
[Presentation] 筋細胞におけるミトコンドリア内酸化ストレスは呼吸鎖を障害し著しい運動能力の低下をきたす2010
- Author(s)
  野尻英俊, 桑原宏朋, 森川大智, 斎田良知, 金子和夫, 清水孝彦
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21791415
[Presentation] Copper/zinc superoxide dismutase deficiency causes low turnover osteopenia via osteoblastic dysfunction2009
- Author(s)
  野尻英俊
- Organizer
  第31回アメリカ骨代謝学会
- Place of Presentation
  アメリカ・デンバー
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21791416
[Presentation] Chondrocyte-specific Deletion of Sod2 Exacerbates Cartilage Degeneration Associated with Low Mitochondrial Membrane Potential in Mice.
- Author(s)
  Koike M, Nojiri H
- Organizer
  American Society for Bone and Mineral Research (ASBMR) 2014 Annual Meeting
- Place of Presentation
  Houston
- Year and Date
  2014-09-12 – 2014-09-15
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] 骨細胞における酸化ストレスは骨リモデリングバランスの破綻をもたらす
- Author(s)
  小林慶司, 野尻英俊, 齋田良知, 森川大智, 小池正人, 小澤裕介, 麻生義則, 金子和夫, 清水孝彦
- Organizer
  日本整形外科学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] Sod2 deficiency in chondrocytes accelerates age-related osteoarthritis in mice.
- Author(s)
  Koike M, Nojiri H
- Organizer
  2014 Osteoarthritis Research Society International (OARSI) world congress 2014
- Place of Presentation
  Paris
- Year and Date
  2014-04-24 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] OA発症メカニズム
- Author(s)
  小池正人、野尻英俊
- Organizer
  第29回日本整形外科基礎学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] Chondrocyte-specific deletion of Sod2 exacerbates age-related cartilage degeneration in mice.
- Author(s)
  Koike M, Nojiri H
- Organizer
  Australia and New Zealand Bone & Mineral Society (ANZBMS) 24th Annual Scientific Meeting
- Place of Presentation
  Queenstown
- Year and Date
  2014-09-07 – 2014-09-10
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] 関節軟骨におけるSod2欠損は加齢性軟骨変性を助長する
- Author(s)
  小池正人、野尻英俊
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26462319
[Presentation] SOD2 deficiency in chondrocytes accelerates age-related osteoarthritis in mice
- Author(s)
  M. Koike, H. Nojiri, Y. Ozawa, K. Watanabe, I. Masuda, Y. Muramatsu, H. Kaneko, D. Morikawa, K. Kobayashi, Y. Saita, T. Sasho, T. Shirasawa, K. Yokote, K. Kaneko, T. Shimizu
- Organizer
  Osteoarthritis and Cartilage 2014 World Congress
- Place of Presentation
  Paris, France
- Year and Date
  2014-04-24 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-24791568
[Presentation] Superoxide dismutase 2 deficiency in osteocytes causes age-related bone loss associated with impairment of bone remodeling.
- Author(s)
  Takahiko Shimizu, Keiji Kobayashi, Hidetoshi Nojiri.
- Organizer
  The Japan-Korea Joint Symposium 2014
- Place of Presentation
  Jeju (Korea)
- Year and Date
  2014-06-20 – 2014-06-21
- Invited
- Data Source
  KAKENHI-PROJECT-26462283

1. SHIMIZU Takahiko (40301791)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. SAITA Yoshitomo (00534885)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. ASOU Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 丸山祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 糸魚川善昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NOJIRI Hidetoshi 野尻 英俊

野尻 英俊 ノジリ ヒデトシ

Research Projects

Research Products

Co-Researchers

Pathological Significance of Oxidative Stress in Ligamentum Flavum Alterations of Spinal Canal StenosisPrincipal Investigator

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脊柱後弯症における傍脊柱筋内酸化ストレスの病理的意義の解明Principal Investigator

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Verification of the usefulness of oxidative stress regulation for functional decline associated with age-related degeneration of locomotive organsPrincipal Investigator

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Pathological role of mitochondrial oxidative stress in cartilage degenerationPrincipal Investigator

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Oxidative stress in bone regulates skeletal homeostasis in mice

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The role of oxidative stress in the maintenance of bone metabolism

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Analysis of pathological role of cytoplasmic oxidative stress in disuse bone atrophy.Principal Investigator

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Molecular analysis for oxidative stress-induced senescent motor weaknessPrincipal Investigator

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The development and analyses of the mouse model of age-related osteoporosis.

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[Book] Systems Biology of Free Radicals and Antioxidants2014

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[Book] Aging: Oxidative Stress and Dietary Antioxidants2014

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[Journal Article] Decreased grip strength is associated with paraspinal muscular oxidative stress in female lumbar degenerative disease patients2024

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[Journal Article] Association of Superoxide‐Induced Oxidative Stress With Rotator Cuff Tears in Human Patients2019

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[Journal Article] Antioxidant treatment with vitamin C attenuated rotator cuff degeneration caused by oxidative stress in Sod1-deficient mice.2018

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Journal Title

NOJIRI Hidetoshi 野尻英俊

野尻英俊ノジリヒデトシ