HIESHIMA Kunio 稗島州雄

… Alternative Names

稗島州邦雄ヒエシマクニオ

稗島州男ヒエシマクニオ

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Researcher Number	10322570
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2011: Kinki University, SCHOOL OF MEDICINE, ASSOCIATE PROFESSOR 2008: 近畿大学, 准教授, 医学部 2000 – 2006: 近畿大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Virology / Immunology / Immunology / Virology Except Principal Investigator Biological Sciences / Immunology / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator ケモカイン / HTLV-1 / Tax / CCL22 / c-Maf / CCR4 / ATL / CXCR4 / CCR5 / SDF-1 … More / RANTES / HIV-1 / KNOCK-DOWN / ICM / HEMATOPOIESIS / DEVELOPMENT / CHEMOKINE / ZEBRAFISH / 遺伝子ノックダウン / 内細胞塊 / 造血 / 発生 / ゼブラフィッシュ / mucosal immunity / plasma cells / antimicrobial activity / salivary gland / exocrine gland / chemokine / 粘膜免疫 / 形質細胞 / 抗菌 / 唾液腺 / 外分泌腺 / Fc chimera / Chemokine / Fcキメラ / がん化 / T細胞 / eEF1A2 … More Except Principal Investigator CCR4 / 制御性T細胞 / 転写因子 / ケモカイン受容体 / ATL / Ets-1 / IL-21 / CCR10 / JunD / Fra-2 / Th2細胞 / 発がん遺伝子 / 白血病 / ケモカイン / Vitamin D3 receptor / vitamin D / transcription factor / mucosal immunity / plasma cell / Ikaros / Ets / プローモーター / ケモカインレセプター / ビタミンDレセプター / ビタミンD / 粘膜免疫 / 形質細胞 / Bc1-6 / MDM2 / c-Myb / CTCL / T細胞分化 / 胸腺 / ブレオマイシン誘導肺線維症 / MDC / TARC / アトピー / 喘息 / アレルギー / Treg / Th2 / CCL22 / CCL17 / 原がん遺伝子 / GATA-3 / リンパ節転移 / 肺がん Less

TaxによるeEF1A2の誘導とそのHTLV-1によるT細胞がん化での役割の解明Principal Investigator
- Principal Investigator
  
  稗島州雄
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kinki University
新規ATL発がん遺伝子Fra-2の発現と機能解析
- Principal Investigator
  
  義江修
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kinki University
Study on the pathophysiological role of the Th2-type chemokine receptor CCR4
- Principal Investigator
  
  YOSHIE Osamu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kinki University
ATLにおけるケモカイン受容体CCR4高頻度発現と発がん機構との関係の解明
- Principal Investigator
  
  義江修
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kinki University
ROLE OF TRANSCRIPTION FACTOR C-MAF IN THE HTLV-1 LATENT INFECTIONPrincipal Investigator
- Principal Investigator
  
  HIESHIMA Kunio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kinki University
ATLにおけるケモカイン受容体CCR4高頻度発現と発がん機構との関係
- Principal Investigator
  
  義江修
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kinki University
Transcriptional regulation of CCR10 expression in plasma cells
- Principal Investigator
  
  YOSHIE Osamu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kinki Univeristy
がん細胞のリンパ節転移に関与するケモカイン及び受容体の探索と分子標的治療への応用
- Principal Investigator
  
  済木育夫
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
FUNCTIONAL ANALYSIS OF ZEBRAFISH CC CHEMOKINES DURING EARLY DEVELOPMENTPrincipal Investigator
- Principal Investigator
  
  HIESHIMA Kunio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KINKI UNIVERSITY
CCL28 Has a Dual Role in Mucosal Immunity as Chemokine with a Broad-Spectrum Antimicrobial ActivityPrincipal Investigator
- Principal Investigator
  
  HIESHIMA Kunio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kinki University
AN ANALYSIS OF THE INHIBITION OF HIV-1 INFECTION BY CHEMOKINE-FC CHIMERAPrincipal Investigator
- Principal Investigator
  
  HIESHIMA Kunio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  KINKI UNIVERSITY

All 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Expression of CCL17 and CCL22 by latent membrane protein 1-positive tumor cells in age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorder.2008
- Author(s)
  Takegawa S, Jin Z, Nakayama T, Oyama T, Hieshima K, Nagakubo D, Shirakawa AK, Tsuzuki T, Nakamura S, Yoshie O
- Journal Title
  
  Cancer Sci 99
  
  Pages: 296-302
- NAID
  10024002305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390277
[Journal Article] Tax-inducible production of CC chemokine ligand 22 by human T cell leukemia virus type 1(HTLV-1)-infected T cells promotes preferential transmission of HTLV-1 to CCR4-expressing CD4+T cells.2008
- Author(s)
  Hieshima K, Nagakubo D, Nakayama T, Shirakawa AK, Jin Z, Yoshie O.
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 931-939
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Journal Article] Tax-inducible production of CC chemokine ligand 22 by human T cell leukemia virus type 1 (HTLV-1)-infected T cells promotes preferential transmission of HTLV-1 to CCR4-expressing CD4+ T cells.2008
- Author(s)
  Hieshima K, Nagakubo D, Nakayama T, Shirakawa AK, Jin Z, Yoshie O
- Journal Title
  
  J. Immunol 180
  
  Pages: 931-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390277
[Journal Article] Differential regulatory function of resting and preactivated allergen-specific CD4+CD25+ regulatory T cells in Th2-type airway inflammation.2008
- Author(s)
  Saito K, Torii M, Ma N, Tsuchiya T, Wang L, Hori T, Nagakubo D, Nitta N, Kanegasaki S, Hieshima K, Yoshie O, Gabazza EC, Katayama N, Shiku H, Kuribayashi K, Kato T
- Journal Title
  
  J. Immunol 181
  
  Pages: 6889-6897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390277
[Journal Article] Tax-inducible production of CC chemokine ligand 22 by human T cell leukemia Virus type 1(HTLV-1)-infected T cells promotes preferelltialtransmission of HTLV-1 to CCR4-expressing CD4+Tcells2008
- Author(s)
  Hieshima, K
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 931-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590457
[Journal Article] Tax-inducible production of CC chemokine ligand 22 by human T cell leukemia virus type 1 (HTLV-1)-infected T cells promotes preferential transmission of HTLV-1 to CCR4-expressing CD4+ T cells2008
- Author(s)
  Hieshima K
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 931-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012047
[Journal Article] Tax-inducible production of CC chemokine ligand 22 by human T cell leukemia virus type 1 (HTLV-1)-infected T cells promotes preferential transmission of HTLV-1 to CCR4-expressing CD4+ T cells2008
- Author(s)
  Hieshima, K
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 931-939
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590457
[Journal Article] Expression of CCR9 in HTLV-1+T cells and ATL cells expressing Tax.2007
- Author(s)
  Nagakubo D, Jin Z, Hieshima K, Nakayama T, Shirakawa AK, Tanaka Y, Hasegawa H, Hayashi T, Tsukasaki K, Yamada Y, Yoshie O.
- Journal Title
  
  International Journal of Cancer. 120
  
  Pages: 1591-1597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Journal Article] Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia.
- Author(s)
  Nakayama T, Hieshima K, Arao T, Jin Z, Nagakubo D, Shirakawa AK, Yamada Y, Fujii M, Oiso N, Kawada A, Nishio K, Yoshie O.
- Journal Title
  
  Oncogene (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] Tax発現HTLV-1感染T細胞における翻訳伸長因子eEFlA2の細胞増殖/生存における役割2009
- Author(s)
  稗島州雄
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21590516
[Presentation] Taxによる翻訳伸長因子eEFlA2の誘導とそのHTLV-1によるT細胞がん化での役割の解明2009
- Author(s)
  稗島州雄
- Organizer
  HTLV-1研究会
- Place of Presentation
  東京大学医科学研究所(東京都)
- Year and Date
  2009-08-30
- Data Source
  KAKENHI-PROJECT-21590516
[Presentation] T細胞依存性の好酸球性気道炎症に対するCCR4拮抗薬の作用2008
- Author(s)
  神沼修、大友隆之、森晶夫、長久保大輔、稗島州雄、義江修、鈴木一矢、廣井隆親
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-19390277
[Presentation] 加齢関連EBV+B細胞リンパ増殖症における多様なケモカインの発現2008
- Author(s)
  義江修、竹川澄男、中山隆志、白川愛子、樋口智紀、長久保大輔、重田暁子、稗島州雄、中村栄男
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390277
[Presentation] CCR4を発現するATLとCTCLにおけるFra-2の異常発現2008
- Author(s)
  中山隆志、樋口智紀、竹川澄男、長久保大輔、重田暁子、白川愛子、稗島州雄、義江修
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390277
[Presentation] HTLV-1 Tax-induced CCL22 promotes primary infection of HTLV-1 to peripheral blood CCR4+CD4+ T cells.2007
- Author(s)
  Hieshima K, Nakayama T, Nagakubo D, Shirakawa AK, Jin Z, Yoshie 0.
- Organizer
  The 66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] HTLV-1 Tax-induced CCL22 promotes cell-cell interactions between HTLV-1-infected cells and peripheral blood CCR4+CD4+ T cells2007
- Author(s)
  Hieshima, K
- Organizer
  The 13th International Conference on Human Retrovirology;HTLV and Related Viruses
- Place of Presentation
  Hakone,Japan
- Year and Date
  2007-05-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] HTLV-1 Tax-induced CCL22 promotes cell-cell interactions between HTLV-1-infected cells and peripheral blood CCR4+CD4+T cells.2007
- Author(s)
  Hieshima K, Nagakubo D, Nakayama T, Shirakawa AK, Yoshie 0.
- Organizer
  The 13th International Conference on Human Retrovirology ; HTLV and Related Viruses
- Place of Presentation
  Hakone, Kanagawa
- Year and Date
  2007-05-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] Role of Fra-2/JunD heterodimer in CCR4 expression and cell proliferation in adult T-cell leulemia2007
- Author(s)
  Nakayama T, Hieshima K, Jin Z, Nagakubo D, Shirakawa AK, Yoshie O
- Organizer
  The 37th Annual Meeting of Japanese Society for Immunology
- Place of Presentation
  Tokyo
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] HTLV-1 Tax-induced CCL22 promotes cell-cell interactions between HTLV-1-infected cells and peripheral blood CCR4+CD4+T cells2007
- Author(s)
  Hieshima, K
- Organizer
  The 13th International Conference on Human RetroVirology;HTLV and Related Viruses
- Place of Presentation
  Hakone,Japan
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] Involvement of fra-2 and JunD in CCR4 expression and cell proliferation in adult T cell leukemia.2007
- Author(s)
  Nakayama T, Hieshima K, Jin Z, Nagakubo D, Shirakawa AK, Yamada Y, Fujii M, Yoshie 0
- Organizer
  The 13th International Conference on Human Retrovirology ; HTLV and Related Viruses
- Place of Presentation
  Hakone, Kanagawa
- Year and Date
  2007-05-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] O. Role of Fra-2/JunD heterodimer in CCR4 expression and cell proliferation in adult T-cell leukemia.2007
- Author(s)
  Nakayama, T., Hieshima, K., Jin, Z., Nagakubo, D., Shirakawa, A., Yoshie, O
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390277
[Presentation] HTLV-1のCD4+ T細胞への感染におけるケモカイン/ケモカイン受容体CCL22/CCR4の役割2007
- Author(s)
  稗島州雄、中山隆志、白川愛子、義江修
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19390277
[Presentation] Role of CCL22/CCR4 in the HTLV-1 infection to CD4+ T cells.2007
- Author(s)
  Hieshima K, Nagakubo D, Nakayama T, Shirakawa AK, Jin Z, Yoshie 0.
- Organizer
  The 55th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  Sapporo
- Year and Date
  2007-10-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457
[Presentation] HTLV-1 Tax誘導性ケモカインCCL22のHTLV-1初期感染における役割2007
- Author(s)
  稗島州雄、中山隆志、長久保大輔、白川愛子、金哲、義江修
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390277
[Presentation] Fra-2とJunDのヘテロダイマーはATL細胞におけるCCR4発現と細胞増殖を促進する2007
- Author(s)
  中山隆志、稗島州雄、金哲、長久保大輔、白川愛子、山田恭暉、藤井雅寛、義江修
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390277
[Presentation] Expression of Chemokine MDC/CCL22 in HTLV-1-infected cells.2006
- Author(s)
  Hieshima K, Nakayama T, Shirakawa AK, Fujii M, Yoshie 0.
- Organizer
  The 54th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  Nagoya
- Year and Date
  2006-11-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590457

1. YOSHIE Osamu (10166910)

# of Collaborated Projects: 11 results

# of Collaborated Products: 19 results
2. NAKAYAMA Takashi (60319663)

# of Collaborated Projects: 6 results

# of Collaborated Products: 8 results
3. NAGAKUDO Daisuke (10368293)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. SHIRAKAWA Aiko (30260285)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 済木育夫 (80133776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 櫻井宏明 (00345571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小泉桂一 (10334715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 重田暁子 (50420435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 今野愛子

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

HIESHIMA Kunio 稗島 州雄

稗島 州邦雄 ヒエシマ クニオ

稗島 州男 ヒエシマ クニオ

Research Projects

Research Products

Co-Researchers

TaxによるeEF1A2の誘導とそのHTLV-1によるT細胞がん化での役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規ATL発がん遺伝子Fra-2の発現と機能解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the pathophysiological role of the Th2-type chemokine receptor CCR4

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ATLにおけるケモカイン受容体CCR4高頻度発現と発がん機構との関係の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ROLE OF TRANSCRIPTION FACTOR C-MAF IN THE HTLV-1 LATENT INFECTIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ATLにおけるケモカイン受容体CCR4高頻度発現と発がん機構との関係

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transcriptional regulation of CCR10 expression in plasma cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん細胞のリンパ節転移に関与するケモカイン及び受容体の探索と分子標的治療への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

FUNCTIONAL ANALYSIS OF ZEBRAFISH CC CHEMOKINES DURING EARLY DEVELOPMENTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CCL28 Has a Dual Role in Mucosal Immunity as Chemokine with a Broad-Spectrum Antimicrobial ActivityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

AN ANALYSIS OF THE INHIBITION OF HIV-1 INFECTION BY CHEMOKINE-FC CHIMERAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of CCL17 and CCL22 by latent membrane protein 1-positive tumor cells in age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorder.2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Tax-inducible production of CC chemokine ligand 22 by human T cell leukemia virus type 1(HTLV-1)-infected T cells promotes preferential transmission of HTLV-1 to CCR4-expressing CD4+T cells.2008

Author(s)

Journal Title

HIESHIMA Kunio 稗島州雄

稗島州邦雄ヒエシマクニオ

稗島州男ヒエシマクニオ