Horikawa Yukio 堀川幸男

… Alternative Names

HORIKAWA Yukio 堀川幸男

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Researcher Number	10323370
Other IDs
Affiliation (Current)	2025: 岐阜大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2009 – 2024: 岐阜大学, 医学部附属病院, 准教授 2009: 岐阜大学, 医学部付属病院, 准教授 2008: 岐阜大学, 医学部・附属病院, 准教授 2007: 岐阜大学, 医学部付属病院, 准教授 2000 – 2005: 群馬大学, 生体調節研究所, 助教授
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 52050:Embryonic medicine and pediatrics-related / Biological Sciences / Pediatrics Except Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related / Metabolomics / Health science and related fields / Eating habits / Integrated Nutrition Science / Pediatrics / Biological Sciences
Keywords	Principal Investigator MODY / 2型糖尿病 / calpain-10 / SNPs / カルパイン10 / アデノウィルス / HNF / 関連解析 / マイクロアレイ / SNP … More / EST / コピー数変異 / インスリン分泌 / エクソーム / インスリン分泌不全 / 原因遺伝子 / レギュローム / トランスクリプトーム / 細胞骨格分子 / 候補遺伝子パネル / 遺伝子診断 / 機能ゲノミクス / in situ hybridization / エンハンサー / 次世代シークエンサー / 多因子疾患 / 単一遺伝子疾患 / knockout mice / transgenic mice / type 2 diabetes / 疾患感受性多型 / カルパイン3 / ノックアウトマウス / トランスジェニックマウス / association study / microarray / susceptibility gene to type 2 diabetes / 連鎖不平衡マッピング / 大規模関連解析 / 2型糖尿病感受性遺伝子 / ASSOCIATION STUDY / MI CROARRAY / TYPE 2 DIABETES / CNV / ゲノムコピー数異常　CNV / 連鎖解析 / 若年糖尿病 MODY … More Except Principal Investigator インスリン分泌 / MODY / 糖尿病 / ChREBP / トランスクリプトーム / 転写因子 / ゲノム / 2型糖尿病 / 肥満 / obesity / birth weight / genetics / insulin secretion / type 2 diabetes / EST / 多因子疾患 / 遺伝子異常 / 肝臓 / 小腸 / フルクトース / インスリン分泌不全 / 分子遺伝学 / PPARα / 液性因子 / 膵島 / lipogenesis / Mlx / de novo lipogenesis / 深層学習 / 老年症候群予防 / 地域コホート / 支援アプリ / 個別化栄養療法 / 健診データ / サルコペニア / 機械学習 / 老年症候群 / Liver / Gut microbiota / Acetate / 腸内細菌 / 腸内細菌叢 / 脂肪酸合成 / 酢酸 / スクロース / 肝インスリン抵抗性 / 膵島分泌タンパク / NASH / 分泌タンパク / OSTEONECTIN / 糖尿病大血管症 / 脂肪肝 / インスリン抵抗性 / SPARC / グルカゴン / インスリン / ケトン代謝 / 脂質異常症 / de novo lipoenesis / β-hydroxybutyrate / Fgf-21 / ketone body / Fgf21 / Ketogenesis / liver / hepatocyte / PPAR alpha / 3-OH-butyric acid / Angptl3 / Angptl8 / FGF21 / ケトン食 / association study / SNP / マイクロアレイシステム / MIN6-m9 / ヒト膵ラ氏島遺伝子 / iSNP / mutation screening / transcription factor / 遺伝子変異 / 核内受容体 / HNFカスケード / マイクロアレイ / グルコース / フルクトキナーゼ / Glut5 / 糖代謝 / ブドウ糖 / ケトヘキソキナーゼ / GLUT5 / 遺伝素因 / 生活習慣病 / 若年発症 / 若年 / 遺伝 / 膵ベータ細胞 / 若年糖尿病 / メンデル遺伝 / 再生医療 / 組織特異性 / ランゲルハンス島 / 生活習慣 / 遺伝性疾患 / ChoRE / Klf-10 / glucagon / KLF10 / glucagon receptor / ChREBP標的遺伝子 / 褐色脂肪細胞 / 脂肪分解 / 脂肪合成 / 摂餌量 / 活動量 / SHP / LRH－１ / LRH-1 / グルカゴン受容体 / KLF-10 / 時計遺伝子 / 概日リズム / メタボリックシンドローム / 糖新生 / 肝糖取込み / 脂肪細胞 / ２型糖尿病 / 肝脂質代謝 / 転写標的 / グルココルチコイド / 食欲 / 臓器相関 / 関連解析 / 遺伝子多型 / 脂質代謝 / 代謝症候群 / metabolic syndrome / feedback loop / DEC / BHLHB2 / Metabolic syndrome / Non Alcholic steatohepatitis / Diabetes mellitus / Elovl-6 / FGF-21 / Insulin / circadian rhythm / Lipogenesis / Sharp-2 / Stra13 / Bhlhb2 / Dec1 / Metabolic Syndrome Less

Establishment of Personalized Nutritional Therapy for Prevention of Geriatric Syndrome through Community Cohort and Deep Learning
- Principal Investigator
  
  矢部大介
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto University
  Gifu University
Identification of ChREBP-mediated Acetate Metabolism
- Principal Investigator
  
  IIZUKA Katsumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fujita Health University
  Gifu University
Genetic dissection of rare MODY by multidisciplinary functional genomicsPrincipal Investigator
- Principal Investigator
  
  HORIKAWA YUKIO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gifu University
Identification of a new mechanism for ketogenesis by ChREBP
- Principal Investigator
  
  Iizuka Katsumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Gifu University
Elucidation of the Glucose Homeostasis Mechanism Not Induced by Pancreatic Hormones by Focusing on the Pancreatic Humoral Factor SPARC
- Principal Investigator
  
  Takeda Jun
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  Gifu University
Characterization of impaired regulatory system of insulin synthesis and secretion in MODY.
- Principal Investigator
  
  Takeda Jun
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
A new treatment for metabolic syndrome with references to fructose metabolism
- Principal Investigator
  
  Iizuka Katsumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Gifu University
Identification of the molecular cause of MODY in Japanese by deep sequencing of the regions of the MODY-specific deletion type of Copy Number VariantPrincipal Investigator
- Principal Investigator
  
  Horikawa Yukio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Comprehensive screening of the differentially expressed genes in various conditions for factors involved in the development of endocrine pancreas.
- Principal Investigator
  
  TAKEDA Jun
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Gifu University
Diabetes treatment increasing liver glucose uptake and decreasing fat accumulation
- Principal Investigator
  
  TAKEDA Jun
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Gifu University
The Role of Crosstalk between ChREBP and Clock-related genes in the Development of Metabolic syndrome
- Principal Investigator
  
  IIZUKA Katsumi
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gifu University
膵島特異的遺伝子の発現調節軸に焦点を絞った糖尿病遺伝子の探索
- Principal Investigator
  
  武田純
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
Exploring the method regulating hepatic ChREBP transactiviy.
- Principal Investigator
  
  IIZUKA Katsumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Analysis of inslin secretion insufficiency in type 2 diabetes due to calpain 10 dysfunctionPrincipal Investigator
- Principal Investigator
  
  HORIKAWA Yukio
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  GUNMA UNIVERSITY
Establishment of detection tool for risk of type 2 diabetes using mice of 'digenic' form of type 2 diabetesPrincipal Investigator
- Principal Investigator
  
  HORIKAWA Yukio
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  GUNMA UNIVERSITY
Establishment of iSNP database and its application to genetic study of type 2 diabetes mellitus.
- Principal Investigator
  
  TAKEDA Jun
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  GUNMA UNIVERSITY
The identification of diabetes susceptibility gene by constructing a pool ofcandidate genes centered on small intestine-pancreaticficell axisPrincipal Investigator
- Principal Investigator
  
  HORIKAWA Yukio
- Project Period (FY)
  2000 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Analysis of HNF-related genes responsible for the development of type 2 diabetes in Japanese
- Principal Investigator
  
  TAKEDA Jun
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  GUNMA UNIVERSITY

[Book] 臨床遺伝専門医テキストシリーズ（成人領域）遺伝子異常による代謝疾患―糖尿病.2021
- Author(s)
  堀川幸男
- Total Pages
  8
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 月刊糖尿病. 堀川幸男(編集)　遺伝子異常と糖尿病　MODY1-62020
- Author(s)
  塩谷真由美、堀川幸男
- Total Pages
  8
- Publisher
  医学出版
- ISBN
  9784287821237
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] DM Ensemble　糖尿病性腎症重症化予防プログラムと糖尿病連携手帳の活用.2020
- Author(s)
  矢部大介、加藤丈博、堀川幸男
- Total Pages
  6
- Publisher
  日本糖尿病協会
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 岐阜県医師会医学雑誌　岐阜県下における「糖尿病連携手帳」の実態調査.2020
- Author(s)
  堀川幸男
- Total Pages
  5
- Publisher
  岐阜県医師会
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 特集糖尿病診療update : 最新の診断と治療　糖尿病に関する教育と支援2020
- Author(s)
  酒井麻有、窪田創大、加藤丈博、堀川幸男、矢部大介
- Total Pages
  6
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 糖尿病・内分泌代謝科 MODY遺伝情報と臨床的知見を糖尿病日常臨床にどう活かすか? 1000万通りの糖尿病個別化医療に向けた遺伝情報の活用のしかた2019
- Author(s)
  堀川幸男
- Total Pages
  7
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 糖尿病単一遺伝子異常による糖尿病-MODY2019
- Author(s)
  堀川幸男
- Total Pages
  3
- Publisher
  日本糖尿病学会
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 内分泌症候群（第3版）若年発症糖尿病(MODY)の遺伝素因と臨床病態について2019
- Author(s)
  塩谷真由美、堀川幸男
- Total Pages
  7
- Publisher
  日本臨床社
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 内分泌症候群（第3版）2019
- Author(s)
  塩谷真由美、堀川幸男
- Total Pages
  642
- Publisher
  日本臨床
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 最新多因子遺伝性疾患2018
- Author(s)
  堀川幸男、塩谷真由美、武田　純
- Total Pages
  292
- Publisher
  メディカルドゥ社
- ISBN
  9784944157266
- Data Source
  KAKENHI-PROJECT-17K19902
[Book] 内分泌代謝専門医ガイドブック2018
- Author(s)
  堀川幸男、武田　純
- Total Pages
  642
- Publisher
  診断と治療社
- ISBN
  9784787822925
- Data Source
  KAKENHI-PROJECT-17K19902
[Book] 内分泌代謝専門医ガイドブック2018
- Author(s)
  堀川幸男、武田　純
- Total Pages
  763
- Publisher
  診断と治療社
- ISBN
  9784787822925
- Data Source
  KAKENHI-PROJECT-18H02779
[Book] 遺伝子異常による糖尿病2015
- Author(s)
  塩谷真由美、堀川幸男、武田　純
- Total Pages
  7
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-25293228
[Book] インスリン分泌-我が国と外国糖尿病予防と治療のエビデンス2012
- Author(s)
  冨田礼子、堀川幸男、武田純
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] Japanese 17q12 Deletion Syndrome with Complex Clinical Manifestations2024
- Author(s)
  Hasegawa Yutaka、Takahashi Yoshihiko、Nagasawa Kan、Kinno Hirofumi、Oda Tomoyasu、Hangai Mari、Odashima Yoshimi、Suzuki Yoko、Shimizu Jun、Ando Toshihiko、Egawa Isao、Hashizume Kouhei、Nata Koji、Yabe Daisuke、Horikawa Yukio、Ishigaki Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 63 Issue: 5 Pages: 687-692
- DOI
  10.2169/internalmedicine.1660-23
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2024-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08582, KAKENHI-PROJECT-23K28017
[Journal Article] Glucokinase Variant Proteins Are Resistant to Fasting-Induced Uridine Diphosphate Glucose-Dependent Degradation in Maturity-Onset Diabetes of the Young Type 2 Patients2023
- Author(s)
  Cho Jaeyong、Horikawa Yukio、Oiwa Yuki、Hosomichi Kazuyoshi、Yabe Daisuke、Imai Takeshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 21 Pages: 15842-15842
- DOI
  10.3390/ijms242115842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K28017
[Journal Article] Unmasked insulinoma occasioned by severe hypoglycemic coma immediately postpartum: a case report2023
- Author(s)
  Matsumoto Kiyoshi、Watanabe Miyu、Takao Ken、Takahashi Hirokazu、Daido Hisashi、Shibata Toshiro、Hirose Tokuyuki、Kato Takehiro、Mizuno Masami、Hirota Takuo、Suwa Tetsuya、Horikawa Yukio、Murakami Takaaki、Yabe Daisuke
- Journal Title
  
  BMC Endocrine Disorders
  
  Volume: 23 Issue: 1 Pages: 168-168
- DOI
  10.1186/s12902-023-01415-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16411, KAKENHI-PROJECT-23K28017
[Journal Article] Effectiveness of countermeasure for polypharmacy by multidisciplinary team review in patients with diabetes mellitus2023
- Author(s)
  Nishida Shohei、Kato Takehiro、Hayashi Yuichi、Yamada Shoya、Fujii Hironori、Yamada Michi、Asai Nao、Shimizu Shinya、Niwa Takashi、Iihara Hirotoshi、Kubota Sodai、Sakai Mayu、Takahashi Yoshihiro、Takao Ken、Mizuno Masami、Hirota Takuo、Kobayashi Ryo、Horikawa Yukio、Yabe Daisuke、Suzuki Akio
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 14 Issue: 10 Pages: 1202-1208
- DOI
  10.1111/jdi.14046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K28017
[Journal Article] Graves' Disease with Thymic Hyperplasia: The Response of the Thyroid Function, Thyrotropin Receptor Autoantibody, and Thymic Size to Thiamazole Treatment2022
- Author(s)
  Tsukada Daichi、Iizuka Katsumi、Takao Ken、Liu Yanyan、Kubota Sodai、Okamoto-Kubota Saki、Sakurai Teruaki、Imaizumi Toshinori、Sakai Mayu、Kato Takehiro、Mizuno Masami、Hirota Takuo、Suwa Tetsuya、Horikawa Yukio、Yamamoto Mayumi、Kubota Sumihisa、Yabe Daisuke
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 18 Pages: 2753-2757
- DOI
  10.2169/internalmedicine.8710-21
- NAID
  130008164547
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-09-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11645, KAKENHI-PROJECT-21K19504
[Journal Article] Glucokinase-maturity onset diabetes mellitus in the young suggested by factory-calibrated glucose monitoring data: a case report2022
- Author(s)
  Nao Nomura, Katsumi Iizuka, Eiichi Goshima, Kazuyoshi Hosomichi, Atsushi Tajima, Sodai Kubota, Yanyan Liu, Ken Takao, Takehiro Kato, Masami Mizuno, Takuo Hirota, Tetsuya Suwa, Yukio Horikawa, Daisuke Yabe
- Journal Title
  
  Endocr J
  
  Volume: 69 Issue: 4 Pages: 473-477
- DOI
  10.1507/endocrj.EJ21-0526
- NAID
  130008118747
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11645, KAKENHI-PROJECT-19KK0237, KAKENHI-PROJECT-21K19504, KAKENHI-PUBLICLY-21H00342
[Journal Article] A case of familial hypocalciuric hypercalcemia type 1 due to CASR p.Pro55Leu mutation2022
- Author(s)
  Sumida Akira、Iizuka Katsumi、Kato Takehiro、Liu Yanyan、Kubota Sodai、Kubota-Okamoto Saki、Sakurai Teruaki、Imaizumi Toshinori、Takahashi Yoshihiro、Mizuno Masami、Takao Ken、Hirota Takuo、Suwa Tetsuya、Horikawa Yukio、Yamamoto Mayumi、Seino Yusuke、Suzuki Atsushi、Yabe Daisuke
- Journal Title
  
  BMC Endocrine Disorders
  
  Volume: 22 Issue: 1 Pages: 164-164
- DOI
  10.1186/s12902-022-01077-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11645, KAKENHI-PROJECT-21K19504
[Journal Article] Effects of ChREBP deficiency on adrenal lipogenesis and steroidogenesis2021
- Author(s)
  Takao Ken、Iizuka Katsumi、Liu Yanyan、Sakurai Teruaki、Kubota Sodai、Kubota-Okamoto Saki、Imaizumi Toshinori、Takahashi Yoshihiro、Rakhat Yermek、Komori Satoko、Hirose Tokuyuki、Nonomura Kenta、Kato Takehiro、Mizuno Masami、Suwa Tetsuya、Horikawa Yukio、Sone Masakatsu、Yabe Daisuke
- Journal Title
  
  Journal of Endocrinology
  
  Volume: 248 Issue: 3 Pages: 317-324
- DOI
  10.1530/joe-20-0442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11645, KAKENHI-PROJECT-18H02779
[Journal Article] A novel RFX6 heterozygous mutation (p.R652X) in maturity‐onset diabetes mellitus: A case report2021
- Author(s)
  Imaki Sakiho、Iizuka Katsumi、Horikawa Yukio、Yasuda Megumi、Kubota Sodai、Kato Takehiro、Liu Yanyan、Takao Ken、Mizuno Masami、Hirota Takuo、Suwa Tetsuya、Hosomichi Kazuyoshi、Tajima Atsushi、Fujiwara Yuuka、Yamazaki Yuji、Kuwata Hitoshi、Seino Yutaka、Yabe Daisuke
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 10 Pages: 1914-1918
- DOI
  10.1111/jdi.13545
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11645, KAKENHI-PROJECT-20K21705, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-18H02779, KAKENHI-PROJECT-19KK0237
[Journal Article] Diagnosis and treatment of primary central nervous system lymphoma with the primary lesion in the hypothalamus: a case report2021
- Author(s)
  Takao Ken、Tani Ayaka、Suwa Tetsuya、Kuwabara-Ohmura Yayoi、Nonomura Kenta、Liu Yanyan、Kato Takehiro、Mizuno Masami、Hirota Takuo、Enya Mayumi、Iizuka Katsumi、Horikawa Yukio、Saigo Chiemi、Kito Yusuke、Miyazaki Tatsuhiko、Ohe Naoyuki、Iwama Toru、Yabe Daisuke
- Journal Title
  
  BMC Endocrine Disorders
  
  Volume: 21 Issue: 1 Pages: 13-13
- DOI
  10.1186/s12902-020-00675-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11645
[Journal Article] A case of MODY5-like manifestations without mutations or deletions in coding and minimal promoter regions of the <i>HNF1B</i> gene2020
- Author(s)
  Kuwabara-Ohmura Yayoi、Iizuka Katsumi、Liu Yanyan、Takao Ken、Nonomura Kenta、Kato Takehiro、Mizuno Masami、Hosomichi Kazuyoshi、Tajima Atsushi、Miyazaki Tatsuhiko、Horikawa Yukio、Yabe Daisuke
- Journal Title
  
  Endocr J
  
  Volume: 67 Issue: 9 Pages: 981-988
- DOI
  10.1507/endocrj.EJ20-0038
- NAID
  130007910088
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11645, KAKENHI-PROJECT-20K21705, KAKENHI-PROJECT-19KK0237, KAKENHI-PUBLICLY-19H05344
[Journal Article] Alcohol-induced impaired insulin secretion in a Japanese population: Five-year follow-up in the Gifu Diabetes Study2020
- Author(s)
  Ueda N, Yamamoto M, Nakamura M, Motooka Y, Nakayama Y, Nonoyama,Y, Oba S, Horikawa Y, Nagata C, and Yabe D; Gifu Diabetes Study Group
- Journal Title
  
  J Diabetes Investig
  
  Volume: 11 Issue: 5 Pages: 1207-1214
- DOI
  10.1111/jdi.13260
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] Periodontal disease may be associated with the occurrence of diabetic retinopathy: A subgroup analysis of the survey of the Diabetes Coordination Notebook in Gifu2020
- Author(s)
  Horikawa Y, Suzuki A, Enya M, Hashimoto K, Nishida S, Kobayashi R, Ohashi T, Yamazaki F, Totani R, Kobayashi H, Yamamoto M, Itoh Y and Takeda J
- Journal Title
  
  Exp Clin Endocrinol Diabetes
  
  Volume: - Issue: 04 Pages: 231-238
- DOI
  10.1055/a-0879-1890
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] L-Arginine prevents cereblon-mediated ubiquitination of glucokinase and stimulates glucose-6-phosphate production in pancreatic β-cells2020
- Author(s)
  Cho J, Horikawa Y, Enya M, Takeda J, Imai Y, Imai Y, Handa H, and Imai T
- Journal Title
  
  Commun Biol
  
  Volume: 3 Issue: 1 Pages: 497-497
- DOI
  10.1038/s42003-020-01226-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] A case of MODY5-like manifestations without mutations or deletions in coding and minimal promoter regions of the HNF1B gene.2020
- Author(s)
  Kuwabara-Ohmura Y , Iizuka K , Liu Y , Takao K , Nonomura K , Kato T , Mizuno M , Hosomichi K , Tajima A , Miyazaki T , Horikawa Y , Yabe D
- Journal Title
  
  Endocrine Journal
  
  Volume: in press
- NAID
  130007910088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00850
[Journal Article] Effect of hypertriglyceridemia in dyslipidemia-induced impaired glucose tolerance and sex differences in dietary features associated with hypertriglyceridemia among the Japanese population: The Gifu Diabetes Study.2020
- Author(s)
  Nonoyama Y, Yamamoto M, Oba S, Horikawa Y, Nagata C, Yabe D, and Takeda J; Gifu Diabetes Study Group.
- Journal Title
  
  J Diabetes Investig
  
  Volume: - Issue: 5 Pages: 771-780
- DOI
  10.1111/jdi.13398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] A case of MODY5-like manifestations without mutations or deletions in coding and minimal promoter regions of the HNF1B gene.2020
- Author(s)
  Kuwabara-Ohmura y, Iizuka K, Liu Y, Takao K, Nonomura K, T Kato, Mizuno M, Hosomichi K, Miyazaki T, Horikawa Y, Yabe D
- Journal Title
  
  Endocr J
  
  Volume: -
- NAID
  130007910088
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] Genetic dissection and clinical features of MODY6 (NEUROD1-MODY)2019
- Author(s)
  Horikawa Y and Enya M.
- Journal Title
  
  Curr Diab Rep
  
  Volume: 19 Issue: 3 Pages: 12-12
- DOI
  10.1007/s11892-019-1130-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] Knowledge of diabetes and its determinants: a cross-sectional study among adults in a Japanese community.2019
- Author(s)
  Oba S, Yamamoto M, Horikawa Y, Suzuki E, Nagata C, Takeda J, and the Gifu Diabetes Study Group
- Journal Title
  
  BMJ Open
  
  Volume: 9 Issue: 5 Pages: e024556-e024556
- DOI
  10.1136/bmjopen-2018-024556
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] Clinical manifestations of a sporadic maturity-onset diabetes of the young (MODY) 5 with a whole deletion of <i>HNF1B</i> based on 17q12 microdeletion2019
- Author(s)
  Omura Yoshiyuki、Yagi Kunimasa、Honoki Hisae、Iwata Minoru、Enkaku Asako、Takikawa Akiko、Kuwano Takahide、Watanabe Yoshiyuki、Nishimura Ayumi、Liu Jianhui、Chujo Daisuke、Fujisaka Shiho、Enya Mayumi、Horikawa Yukio、Tobe Kazuyuki
- Journal Title
  
  Endocr J
  
  Volume: 66 Issue: 12 Pages: 1113-1116
- DOI
  10.1507/endocrj.EJ19-0020
- NAID
  130007772410
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-18H02779
[Journal Article] MODY遺伝情報と臨床的知見を糖尿病日常臨床にどう活かすか?2019
- Author(s)
  堀川幸男
- Journal Title
  
  科学評論社
  
  Volume: 48 Pages: 181-187
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion2018
- Author(s)
  Niwa Hiroyuki、Iizuka Katsumi、Kato Takehiro、Wu Wudelehu、Tsuchida Hiromi、Takao Ken、Horikawa Yukio、Takeda Jun
- Journal Title
  
  Nutrients
  
  Volume: 10 Issue: 3 Pages: 321-321
- DOI
  10.3390/nu10030321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00850, KAKENHI-PROJECT-17K19902
[Journal Article] Maturity-onset diabetes of the young (MODY) as a model for elucidating the multifactorial origin of type 2 diabetes mellitus.2018
- Author(s)
  Horikawa Y.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 9 Issue: 4 Pages: 704-712
- DOI
  10.1111/jdi.12812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02779, KAKENHI-PROJECT-17K19902
[Journal Article] No novel, high penetrant gene might remain to be found in Japanese patients with unknown MODY2018
- Author(s)
  Horikawa Y, Hosomichi K, Ishiura H, Suzuki Y, Tsuji S, Inoue I, Takeda J
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 印刷中 Issue: 7 Pages: 821-829
- DOI
  10.1038/s10038-018-0449-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02373, KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-18H02779, KAKENHI-PROJECT-17K19804
[Journal Article] ChREBP-Knockout Mice Show Sucrose Intolerance and Fructose Malabsorption2018
- Author(s)
  Kato Takehiro、Iizuka Katsumi、Takao Ken、Horikawa Yukio、Kitamura Tadahiro、Takeda Jun
- Journal Title
  
  Nutrients
  
  Volume: 10 Issue: 3 Pages: 340-340
- DOI
  10.3390/nu10030340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00850, KAKENHI-PROJECT-17K19902
[Journal Article] 若年発症成人型糖尿病(MODY) -多因子型コモン2型糖尿病のモデル疾患として2018
- Author(s)
  堀川幸男、塩谷真由美
- Journal Title
  
  プラクティス
  
  Volume: 35 Pages: 378-383
- Data Source
  KAKENHI-PROJECT-18H02779
[Journal Article] Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B2018
- Author(s)
  Hatta Tomohisa、Iemura Shun-ichiro、Ohishi Tomokazu、Nakayama Hiroshi、Seimiya Hiroyuki、Yasuda Takao、Iizuka Katsumi、Fukuda Mitsunori、Takeda Jun、Natsume Tohru、Horikawa Yukio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16756-16756
- DOI
  10.1038/s41598-018-35204-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00850, KAKENHI-PROJECT-18H02779, KAKENHI-PROJECT-17K19902, KAKENHI-PUBLICLY-18H04633
[Journal Article] No novel, high penetrant gene might remain to be found in Japanese patients with unknown MODY.2018
- Author(s)
  Horikawa Y, Hosomichi K, Enya M, Ishiura H, Suzuki Y, Tsuji S, Sugano S, Inoue I, and Takeda J.
- Journal Title
  
  J Hum Genet
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19902
[Journal Article] ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different Manners2018
- Author(s)
  Iizuka Katsumi、Takao Ken、Kato Takehiro、Horikawa Yukio、Takeda Jun
- Journal Title
  
  Nutrients
  
  Volume: 10 Issue: 11 Pages: 1699-1699
- DOI
  10.3390/nu10111699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00850, KAKENHI-PROJECT-17K19902
[Journal Article] Complementary glucagonostatic and insulinotropic effects of DPP-4 inhibitors in the glucose-lowering action of Japanese patients with type 2 diabetes2016
- Author(s)
  Hashimoto K, Horikawa Y, Takeda J
- Journal Title
  
  Diabetol Int
  
  Volume: 7 Issue: 2 Pages: 133-140
- DOI
  10.1007/s13340-015-0219-x
- NAID
  40020883253
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293228, KAKENHI-PROJECT-26293246
[Journal Article] Complementary glucagonostatic and insulinotropic effects of DPP-4 inhibitors in the glucose-lowering action in Japanese patients with type 2 diabetes2016
- Author(s)
  Ken-ichi Hashimoto,Yukio Horikawa,Jun Takeda
- Journal Title
  
  Diabetology International
  
  Volume: 7 Pages: 133-144
- NAID
  40020883253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293246
[Journal Article] Increased plasma serotonin metabolite 5-hydroxyindole acetic acid concentrations are associated with impaired systolic and late diastolic forward flows during cardiac cycle and elevated resistive index at popliteal artery and renal insufficiency in type 2 diabetic patients with microalbuminuria2016
- Author(s)
  Jun Saito, Eiji Suzuki, Yoshitaka Tajima, Kazuhisa Takami, Yukio Horikawa,Jun Takeda
- Journal Title
  
  Endocr J
  
  Volume: 63 Issue: 1 Pages: 69-76
- DOI
  10.1507/endocrj.EJ15-0343
- NAID
  130005121499
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293246
[Journal Article] Elevated plasma B-type natriuretic peptide concentration and resistive index, but not decreased aortic distensibility, associate with impaired blood flow at popliteal artery in type 2 diabetic patients2015
- Author(s)
  Tajima Y, Suzuki E, Saito J, Murase H, Horikawa Y Takeda J
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 6 Pages: 503-511
- DOI
  10.1507/endocrj.EJ14-0608
- NAID
  130005085771
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293228, KAKENHI-PROJECT-26293246
[Journal Article] Fat and carbohydrate in western diet contribute differently to hepatic lipid accumulation2015
- Author(s)
  Wudelehu Wu, Hiromi Tsuchida, Takehiro Kato, Horoyuki Niwa, Yukio Horikawa, Jun Takeda, Katsumi Iizuka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 461 Issue: 4 Pages: 681-686
- DOI
  10.1016/j.bbrc.2015.04.092
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26500005, KAKENHI-PROJECT-25293228, KAKENHI-PROJECT-26293246
[Journal Article] Association of genetic variants of the incretin-related genes with quantitative traits and occurrence of type 2 diabetes in Japanese.2014
- Author(s)
  Enya M, Horikawa Y, Iizuka K, Takeda J.
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 1 Pages: 350-361
- DOI
  10.1016/j.ymgmr.2014.07.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293228
[Journal Article] Active and passive exposure to tobacco smoke in relation to insulin sensitivity and pancreatic b-cell function in Japanese.2014
- Author(s)
  Oba S, Suzuki E, Yamamoto M, Horikawa Y, Nagata C, Takeda J.
- Journal Title
  
  Diabetes and metabolism
  
  Volume: nd Issue: 2 Pages: 160-7
- DOI
  10.1016/j.diabet.2014.09.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293228, KAKENHI-PROJECT-26460758, KAKENHI-PROJECT-26293246
[Journal Article] LRH-1 heterozygous knockout mice are prone to mild obesity.2014
- Author(s)
  Hattori T, Iizuka K, Horikawa Y, Takeda J
- Journal Title
  
  Endocr. J.
  
  Volume: 61 Pages: 471-480
- NAID
  130004443971
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293228
[Journal Article] Screening of diabetes of youth for hepatocyte nuclear factor 1 mutations: clinical phenotype of HNF-1β－related maturity-onset diabetes of the young and HNF-1α-related maturity-onset diabetes of the young in Japanese.2014
- Author(s)
  Y. Horikawa, M. Enya, N. Fushimi, Y. Fushimi, and J. Takeda.
- Journal Title
  
  Diabetic Med.
  
  Volume: 31 Pages: 721-727
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293246
[Journal Article] LRH-1 heterozygous knockout mice are prone to mild obesity2014
- Author(s)
  Hattori T, Iizuka K, Horikawa Y, Takeda J
- Journal Title
  
  Endocr J
  
  Volume: 61 Issue: 5 Pages: 471-480
- DOI
  10.1507/endocrj.EJ14-0017
- NAID
  130004443971
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973, KAKENHI-PROJECT-25293228
[Journal Article] LRH-1 heterozygous knockout mice are prone to mild obesity.2014
- Author(s)
  T. Hattori, K. Iizuka, Y. Horikawa and J. Takeda.
- Journal Title
  
  Endocr Journal
  
  Volume: 61 Pages: 471-480
- NAID
  130004443971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670432
[Journal Article] Screening of diabetes of youth for HNF-1 mutations: clinical phenotype of HNF1β-related maturity-onset diabetes of the young and HNF1α-related maturity-onset diabetes of the young in Japanese2014
- Author(s)
  Y. Horikawa, M. Enya, N. Fushimi, Y. Fushimi and J. Takeda
- Journal Title
  
  Diabetic Medicine
  
  Volume: nd Issue: 6 Pages: 721-727
- DOI
  10.1111/dme.12416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293228, KAKENHI-PROJECT-25670432
[Journal Article] LRH-1 heterozygous knockout mice are prone to mild obesity.2014
- Author(s)
  T. Hattori, K. Iizuka, Y. Horikawa and J. Takeda.
- Journal Title
  
  Endocr J
  
  Volume: 61 Pages: 471-480
- NAID
  130004443971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293246
[Journal Article] Association of genetic variants of the incretin-related genes with quantitative traits and occurrence of type 2 diabetes in Japanese.2014
- Author(s)
  M. Enya, Y. Horikawa, K. Iizuka and J. Takeda.
- Journal Title
  
  Mol. Genet. Metab. Rep
  
  Volume: 1 Pages: 350-361
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293246
[Journal Article] Feedback looping between ChREBP and PPARα in the regulation of lioid metabolism in brown adipose tissue.2013
- Author(s)
  K. Iizuka, W. Wu, Y. Horikawa, M. Saito and J. Takeda.
- Journal Title
  
  Endocr. J
  
  Volume: 60 Pages: 1145-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670432
[Journal Article] Role of glucose-6-phosphate and xylulose-5-phosphate in the regulation of glucose stimulated gene expression in the pancreatic β cell line, INS-1E.2013
- Author(s)
  K. Iizuka, W. Wu, Y. Horikawa and J. Takeda.
- Journal Title
  
  Endocr. J.
  
  Volume: 60 Pages: 473-482
- NAID
  10031170636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670432
[Journal Article] 次世代シークエンサーを用いた糖尿病遺伝子同定戦略2013
- Author(s)
  塩谷　真由美、堀川　幸男
- Journal Title
  
  Diabetes Frontier
  
  Volume: 24 Pages: 321-326
- Data Source
  KAKENHI-PROJECT-25293228
[Journal Article] Role of glucose-6-phosphate and xylulose-5-phosphate in the regulation of glucose-stimulated gene expression in the pancreatic β cell line, INS-1E2013
- Author(s)
  K. Iizuka
- Journal Title
  
  Endocr J
  
  Volume: 60 Issue: 4 Pages: 473-482
- DOI
  10.1507/endocrj.EJ12-0413
- NAID
  10031170636
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184, KAKENHI-PROJECT-22590973
[Journal Article] Role of glucose-6-phosphate and xylulose-5-phosphate in the regulation of glucose stimulated gene expression in the pancreatic β cell line, INS-1E.2013
- Author(s)
  Iizuka K, Wu W, Horikawa Y and Takeda J.
- Journal Title
  
  Endocr J
  
  Volume: 60(4) Pages: 473-482
- NAID
  10031170636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] 脂質異常とインスリン分泌不全2013
- Author(s)
  堀川　幸男
- Journal Title
  
  Diabetes Frontier
  
  Volume: 24 Pages: 396-401
- Data Source
  KAKENHI-PROJECT-25293228
[Journal Article] Feedback looping between ChREBP and PPARα in the regulation of lipid metabolism in brown adipose tissues2013
- Author(s)
  Iizuka K, Wu W, Horikawa Y, Saitio M and Takeda J
- Journal Title
  
  Endocr J
  
  Volume: 60 Issue: 10 Pages: 1145-1153
- DOI
  10.1507/endocrj.EJ13-0079
- NAID
  130004770387
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] A case of glycemic instability and insulin allergy due to anti-insulin antibodies in a patient with type 2 diabetes2012
- Author(s)
  Iizuka K, Tomita R, Horikawa Y, Takeda J.
- Journal Title
  
  Diabetol Int
  
  Volume: 3 Pages: 233-238
- NAID
  10030590194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] Rat glucagon receptor mRNA is directly regulated by glucose through transactivation of the carbohydrate response element binding protein2012
- Author(s)
  Iizuka K, Tomita R, Takeda J, Horikawa Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 417 Issue: 4 Pages: 1107-1112
- DOI
  10.1016/j.bbrc.2011.12.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] Normalization of fasting hyperglycemia is beneficial for successful introduction of small amount of the GLP-1 analog liraglutide in an obese patient with type 2 diabetes mellitus2012
- Author(s)
  Iizuka K, Tomita R, Suwa T, Horikawa Y, Takeda J
- Journal Title
  
  Diabetol Int
  
  Volume: 3 Issue: 1 Pages: 61-64
- DOI
  10.1007/s13340-011-0052-9
- NAID
  40019209011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] Normalization of fasting hyperglycemia is beneficial for successful introduction of small amount of the GLP-1 analog liraglutide in an obese patient with type 2 diabetes mellitus.2012
- Author(s)
  Iizuka K, Tomita R, Suwa T, Horikawa Y, Takeda J.
- Journal Title
  
  Diabetol Int
  
  Volume: 3 Pages: 61-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] Effectiveness of the glucagon test in estimating islet function for liraglutide treatment in a lean diabetic patient with impaired insulin response to glucose: a case report.2012
- Author(s)
  Iizuka K, Tomita R, Horikawa Y, Takeda J.
- Journal Title
  
  Diabetol Int
  
  Volume: 3 Pages: 103-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] A case of glycemic instability and insulin allergy due to anti-insulin antibodies in a patient with type 2 diabetes2012
- Author(s)
  Iizuka K, Tomita R, Horikawa Y, Takeda J
- Journal Title
  
  Diabetol Int
  
  Volume: 3 Issue: 4 Pages: 233-238
- DOI
  10.1007/s13340-012-0077-8
- NAID
  10030590194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] The evaluation of risk factors associated with adverse drug reactions by metformin in type 2 diabetes2012
- Author(s)
  Okayasu S, Kitaichi K, Hori A, Suwa T, Horikawa Y, Yamamoto M, Takeda J, Itoh Y
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35 Pages: 933-937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] Rat glucagon receptor mRNA is directly regulated by glucose through transactivation of the carbohydrate response element binding protein.2012
- Author(s)
  Iizuka K, Tomita R, Takeda J, Horikawa Y
- Journal Title
  
  BBRC
  
  Volume: 417 Pages: 1107-1112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] Effectiveness of the glucagon test in estimating islet function for liraglutide treatment in a lean diabetic patient with impaired insulin response to glucose: a case report2012
- Author(s)
  Iizuka K, Tomita R, Horikawa Y, Takeda J
- Journal Title
  
  Diabetol Int
  
  Volume: 3 Issue: 2 Pages: 103-108
- DOI
  10.1007/s13340-012-0068-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] Synergistic effect of α-glucosidase inhibitors and dipeptidyl peptidase 4 inhibitor treatment2011
- Author(s)
  Horikawa Y, Enya M, Iizuka K, Chen GY, Kawachi S, Suwa T, Takeda J
- Journal Title
  
  J Diabet Invest
  
  Volume: 2 Issue: 3 Pages: 200-203
- DOI
  10.1111/j.2040-1124.2010.00081.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] Krüppel-like factor-10 is directly regulated by carbohydrate response element-binding protein in rat primary hepatocytes2011
- Author(s)
  Iizuka K, Takeda J, Horikawa Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Issue: 4 Pages: 638-643
- DOI
  10.1016/j.bbrc.2011.08.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] Synergistic effect of -glucosidase inhibitors and dipeptidyl peptidase 4 inhibitor treatment2011
- Author(s)
  Yukio Horikawa, Mayumi Enya, Katsumi Iizuka, Gui Ying Chen, Shin-ichi Kawachi, Tetsuya Suwa, Jun Takeda
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: (印刷中,印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] Synergistic effect of α-glucosidase inhibitors and dipeptidyl peptidase 4 inhibitor treatment2011
- Author(s)
  Y.Horikawa, et al
- Journal Title
  
  J.Diabetes Invest.
  
  Volume: 2 Pages: 200-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390184
[Journal Article] DPP-4阻害薬とGLP-1受容体作動薬の使い分けとポジショニング2011
- Author(s)
  飯塚勝美, 堀川幸男, 武田純
- Journal Title
  
  Prog.Med.
  
  Volume: 31 Pages: 1421-1425
- Data Source
  KAKENHI-PROJECT-22590973
[Journal Article] Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes2009
- Author(s)
  K. Iizuka, J. Takeda, Y. Horikawa
- Journal Title
  
  FEBS Lett 583
  
  Pages: 2882-2886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] Hepatic overexpression of dominant negative Mlx improves metabolic profile in diabetes-prone C57BL/6J mice2009
- Author(s)
  K. Iizuka, J. Takeda, Y. Horikawa
- Journal Title
  
  Biochem Biophys Res Commun 379
  
  Pages: 499-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] Identification of minimal promoter and genetic variants of Kruppel-like factor 11 gene and association analysis with type 2 diabetes in Japanese2009
- Author(s)
  E. Kuroda, Y. Horikawa, M. Enya, N. Oda, E. Suzuki, K. Iizuka, J. Takeda
- Journal Title
  
  Endocr J 56
  
  Pages: 275-286
- NAID
  10026913134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] グルコース感受性転写因子-ChREBP(特集栄養シグナルの感じ方・伝え方-細胞生存,糖尿病,肥満,癌との関わり)-(栄養感知とシグナル伝達)2009
- Author(s)
  飯塚勝美, 堀川幸男
- Journal Title
  
  細胞工学 28
  
  Pages: 780-783
- NAID
  40016699749
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] Glucose induces FGF21 mRNA expression through ChREPB activation in rat hepatocytes.2009
- Author(s)
  Iizuka K, Takeda J, Horikawa Y
- Journal Title
  
  FEBS letters 583
  
  Pages: 2882-2886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] グルコース感受性転写因子-ChREBP (特集栄養シグナルの感じ方・伝え方-細胞生存, 糖尿病, 肥満, 癌との関わり)-(栄養感知とシグナル伝達)2009
- Author(s)
  飯塚勝美, 堀川幸男
- Journal Title
  
  細胞工学 28
- NAID
  40016699749
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] Large-scale analysis of glucocorticoid target genes in rat hypothalamus2008
- Author(s)
  H. Sato H, Y. Horikawa, K. Iizuka, N. Sakurai, T. Tanaka, N. Shihara, A. Oshima, J. Takeda, M. Mikuni
- Journal Title
  
  J Neurochem 106
  
  Pages: 805-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping2008
- Author(s)
  K. Iizuka, Y. Horikawa
- Journal Title
  
  Biochem Biophys Res Commun 374
  
  Pages: 95-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] ChREBP:a glucose activated transcription factor involved in the development of Metabolic Syndrome2008
- Author(s)
  Iizuka K, and Horikawa Y
- Journal Title
  
  Endocrine J accepted(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] Mutations in the small heterodimer partner gene increase morbidity risk in Japanese type 2 diabetes patients2008
- Author(s)
  M. Enya, Y. Horikawa, E. Kuroda, K. Yonemaru, N. Tonooka, H. Tomura, N. Oda, N. Yokoi, K. Yamagata, N. Shihara, K. Iizuka, T. Saibara, S. Seino, J. Takeda
- Journal Title
  
  Hum Mutat 29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] ChREBP: a glucose-activated transcription factor involved in the development of metabolic syndrome2008
- Author(s)
  K. Iizuka, Y. Horikawa
- Journal Title
  
  Endocr J 55
  
  Pages: 617-624
- NAID
  10022608828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591035
[Journal Article] Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese2003
- Author(s)
  Horikawa Y, et al.
- Journal Title
  
  J Clin Endocrinol Metab 88
  
  Pages: 244-247
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13204008
[Journal Article] Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese2003
- Author(s)
  Horikawa Y, et al..
- Journal Title
  
  J Clin Endocrinol Metab 88
  
  Pages: 244-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204008
[Presentation] 小腸ChREBPはフルクトースの吸収だけでなく、腸内細菌を介した酢酸産生も調節する2023
- Author(s)
  飯塚勝美　土田宏美　鷹尾賢　劉彦言　窪田創大　窪田紗希　今泉俊則加藤丈博　鈴木渓　富田弘之　堀川幸男　矢部大介
- Organizer
  第66回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K11645
[Presentation] Whole-exome sequencing in a family with multiple cases of early-onset diabetes reveals a candidate causative mutation in the PTF1A gene.2020
- Author(s)
  Tanaka D, Okamoto S, Liu Y, Iizuka K, Hamamoto Y, Horikawa Y, Yabe D, Inagaki N.
- Organizer
  56th Annual Meeting of the European Association for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] High-Sucrose Diet Causes Increased Hepatic Histone Acetylation Due to Increased Bacterial Acetate Production and Reduced Lipogenesis in ChREPB-Deficient Mice.2020
- Author(s)
  Iizuka K, Takao K, Liu Y, Nonomura K, Kato T, Mizuno M, Horikawa Y, Yabe D.
- Organizer
  80th Scientific Sessions, American Diabetes Association.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] 1818-P: High-Sucrose Diet Causes Increased Hepatic Histone Acetylation Due to Increased Bacterial Acetate Production and Reduced Lipogenesis in ChREPB-Deficient Mice2020
- Author(s)
  Katsumi Iizuka, Ken Takao, Yanyan Liu, Kenta Nonomura, Takehiro Kato, Masami Mizuno, Yuka Fujiwara, Hitoshi Kuwata, Yutaka Seino, Yukio Horikawa, Daisuke Yabe
- Organizer
  80TH virtual SCIENTIFIC SESSIONS, The American Diabetes Association's annual Scientific Sessions
- Data Source
  KAKENHI-PROJECT-20K11645
[Presentation] Exome Sequencing in a Family with Multiple Cases of Early-Onset Diabetes Reveals a Candidate Causative Mutation in the PTF1A Gene.2020
- Author(s)
  Tanaka D, Okamoto S, Liu Y, Iizuka K, Hamamoto Y, Horikawa Y, Yabe D, Inagaki N.
- Organizer
  80th Scientific Sessions, American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] RFX6 遺伝子変異を同定した若年発症糖尿病の1 例2020
- Author(s)
  今木咲歩、飯塚勝美、安田愛、窪田創大、加藤丈博、細道一善、田島敦、藤原結花、桑田仁司、堀川幸男、矢部大介
- Organizer
  第94回日本糖尿病学会中部地方会　（会長　堀川幸男）
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] ChREBPとPPARαによるFGF21の転写調節制御の分子機序に関する検討：ChREBP欠損マウスにおけるPPARα活性化薬ぺマフィブラートの効果2020
- Author(s)
  鷹尾賢、飯塚勝美、劉彦言、野々村健太、加藤丈博、水野正巳、堀川幸男、矢部大介
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] SGLT2阻害薬、GLP-1受容体作動薬の治療効果予測因子の検討2020
- Author(s)
  酒井麻有、飯塚勝美、石原拓磨、鷹尾賢、加藤丈博、野々村健太、劉彦言、水野正巳、堀川幸男、矢部大介
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] FGF21誘導におけるChREBPとPPARαの協調作用2019
- Author(s)
  鷹尾　賢、飯塚勝美、加藤丈博、堀川幸男
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] 高ケトン食の有効性安全性に関する検討2019
- Author(s)
  鷹尾　賢、飯塚勝美、堀川幸男、武田純、矢部大介
- Organizer
  第56回　日本臨床分子医学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] 日本人初MODY4（PDX1-MODY）の1症例についての報告2019
- Author(s)
  塩谷　真由美、吉治智志、阿部　恵、濱崎　暁洋、細道　一善、矢部　大介、堀川　幸男
- Organizer
  第64回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] メガゲノミクスによる糖尿病遺伝素因の同定（シンポジウム）2019
- Author(s)
  細道一善、堀川幸男
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] ChREBP欠失マウスではSGLT2阻害薬による血糖低下作用が減弱する2019
- Author(s)
  加藤丈博、飯塚勝美、鷹尾　賢、堀川幸男、矢部大介
- Organizer
  第92回　日本内分泌学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] ChREBP欠失マウスではSGLT2阻害薬による血糖低下作用が現弱する2019
- Author(s)
  加藤丈博、飯塚勝美、鷹尾　賢、堀川幸男
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] ChREBPの肝および血中トリグリセリドに対する調節機序の違い―Fgf21およびAngptl3に注目した解析―2019
- Author(s)
  飯塚勝美、鷹尾賢、加藤丈博、堀川幸男、武田純、矢部大介
- Organizer
  第6回　肝臓と糖尿病・代謝研究会　研究会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] 小腸スクロース/フルクトース代謝におけるChREBPの役割2019
- Author(s)
  加藤丈博、飯塚勝美、堀川幸男、武田純、矢部大介
- Organizer
  第56回　日本臨床分子医学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] FGF-21誘導におけるChREBPとPPARαの協調作用-ペマフィブラートを用いた検討-2019
- Author(s)
  鷹尾賢、飯塚勝美、加藤丈博、堀川幸男、矢部大介
- Organizer
  第92回　日本内分泌学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] 新規インスリン遺伝子変異を同定しMODY10と考えられた1家系2019
- Author(s)
  塩谷　真由美　金子　至寿佳　矢部　大介　堀川　幸男
- Organizer
  第53回日本小児内分泌学会
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] 高ケトン食の安全性・有効性とChREBPが及ぼす影響2018
- Author(s)
  鷹尾　賢, 飯塚勝美, 加藤丈博, 土田宏美, 堀川幸男, 武田　純
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K19902
[Presentation] 高ケトン食の安全性・有効性とChREBPが及ぼす影響2018
- Author(s)
  鷹尾　賢、飯塚勝美、加藤丈博、土田宏美、堀川幸男、武田　純
- Organizer
  第61回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] ChREBPノックアウトマウスはスクロース不耐症のモデルマウスである2018
- Author(s)
  加藤丈博、飯塚勝美、鷹尾　賢、土田宏美、堀川幸男、北村忠弘、武田　純
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19902
[Presentation] ChREBPノックアウトマウスはスクロース不耐症のモデルマウスである2018
- Author(s)
  加藤丈博，飯塚勝美，鷹尾　賢，土田宏美，堀川幸男，北村忠弘，武田　純
- Organizer
  第91回　日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] ChREBPがケトン体代謝に及ぼす役割2018
- Author(s)
  鷹尾　賢、飯塚勝美、加藤丈博、土田宏美、堀川幸男、武田　純
- Organizer
  第91回　日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] 単一遺伝子異常による糖尿病（MODY）表現型への子宮内環境の影響に関する検討2018
- Author(s)
  塩谷真由美、堀川幸男, 水野正巳, 橋本健一,廣田卓男, 諏訪哲也, 武田　純
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] ミグリトール添加スクロース食負荷ChREBPノックアウトマウスは新たなフルクトース不耐症のモデルである2018
- Author(s)
  加藤丈博、飯塚勝美、鷹尾　賢、土田宏美、堀川幸男、北村忠弘、武田　純
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K19902
[Presentation] ChREBPがケトン体代謝に及ぼす役割2018
- Author(s)
  鷹尾　賢、飯塚勝美、加藤丈博、土田宏美、堀川幸男、武田　純
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19902
[Presentation] 遺伝子異常と糖尿病2018
- Author(s)
  堀川幸男 (教育講演)
- Organizer
  第61回日本糖尿病学会年次学術集会.
- Invited
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] ミグリトール添加スクロース食負荷ChREBPノックアウトマウスは新たなフルクトース不耐症のモデルである2018
- Author(s)
  加藤丈博，飯塚勝美，鷹尾　賢，土田宏美，堀川幸男，北村忠弘，武田　純
- Organizer
  第61回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] 腸内細菌叢変化に注目した ChREBP 遺伝子欠失マウスのスクロース不耐症発症機構の検討2018
- Author(s)
  飯塚勝美、加藤丈博、鷹尾賢、堀川幸男、北村忠弘、武田純
- Organizer
  第5回　肝臓と糖尿病・代謝研究会　研究会
- Data Source
  KAKENHI-PROJECT-17K00850
[Presentation] 若年発症糖尿病（MODY）における片親起源効果についての包括的検討2018
- Author(s)
  塩谷真由美、酒井麻有、野々村健太、鷹尾　賢、加藤丈博、水野正巳、橋本健一、廣田卓男、飯塚勝美、諏訪哲也、堀川幸男
- Organizer
  第34回日本糖尿病妊娠学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K19902
[Presentation] 単一遺伝子異常による糖尿病（MODY）表現型への子宮内環境の影響に関する検討2018
- Author(s)
  塩谷真由美、堀川幸男, 水野正巳, 橋本健一,廣田卓男, 諏訪哲也, 武田　純
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K19902
[Presentation] 若年発症糖尿病（MODY）における片親起源効果についての包括的検討2018
- Author(s)
  塩谷真由美、酒井麻有、野々村健太、鷹尾　賢、加藤丈博、水野正巳、橋本健一、廣田卓男、飯塚勝美、諏訪哲也、堀川幸男
- Organizer
  第34回日本糖尿病妊娠学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02779
[Presentation] 高脂肪食誘導性肥満病態における脂質と糖質の役割の違い2017
- Author(s)
  鷹尾賢、飯塚勝美、加藤丈博、土田宏美、丹羽啓之、堀川幸男、武田純
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] 肝VLDL分泌機構に着目した ChREBPとSHPの相互作用についての考察2017
- Author(s)
  丹羽啓之　飯塚勝美　鷹尾賢　加藤丈博　　ウウデレフ　土田宏美　堀川幸男　武田純
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] 小腸と肝臓におけるChREBPのフルクトース代謝への関与2017
- Author(s)
  加藤丈博、飯塚勝美、鷹尾賢、土田宏美、丹羽啓之、北村忠弘、堀川幸男、武田純
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] 当院で経験した MODY1 姉妹 2 例の 4 分娩について2016
- Author(s)
  宮里　舞、和栗　雅子、山田　佑子、光田　信明、塩谷　真由美、堀川　幸男、武田　純、和田　芳直
- Organizer
  第32回日本糖尿病・妊娠学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] Investigation of clinical differences between MODY1 and MODY3 in Japanese2016
- Author(s)
  Mayumi Enya,Yukio Horikawa,Kenichi Hashimoto,Jun Takeda
- Organizer
  The 13th International Congress of Human Genetics（ICHG2016）
- Place of Presentation
  Kyoto
- Year and Date
  2016-04-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] Cross Talk between ChREBP and SHP in Hepatic Glucose and Lipid Metabolism2016
- Author(s)
  Katsumi Iizuka, Hiroyuki Niwa, Wudelehu Wu, Hiromi Tsuchida, Takehiro Kato, Yukio Horikawa, Jun Takeda.
- Organizer
  the American Diabetes Association's 76th Scientific Sessions
- Place of Presentation
  米国ルイジアナ州ニューオリンズ
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] 3T3-L1細胞を用いた脂肪細胞におけるGLP-1受容体の存在についての検証2016
- Author(s)
  丹羽啓之, 飯塚勝美, 呉烏徳勒胡, 堀川幸男, 武田純
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都府京都市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] ミグリトールの脂質代謝への影響に関する検討高コレステロール食負荷マウスを用いた解析2016
- Author(s)
  加藤丈博, 飯塚勝美, 呉烏徳勒胡, 土田宏美, 丹羽啓之, 堀川幸男,北村忠弘,武田純
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都府京都市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] 日本人 MODY1 の特徴についての検討；MODY3 との比較から2016
- Author(s)
  塩谷　眞由美、堀川　幸男、橋本　健一、水野　正巳、廣田　卓男、諏訪　哲也、武田　純
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] 日本人MODY6の４症例についての検討2015
- Author(s)
  塩谷真由美、堀川幸男、橋本健一、廣田卓男、諏訪哲也、間部裕代、福島恵、大橋正明、池田富貴、武田純
- Organizer
  第58回日本糖尿病学会何時学術集会
- Place of Presentation
  下関市
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] 日本人若年糖尿病の新規原因遺伝子同定戦略とその展開2015
- Author(s)
  堀川幸男
- Organizer
  第58回日本糖尿病学会学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 日本人若年糖尿病（MODY）研究における内科-小児科連携構築の提言2015
- Author(s)
  堀川幸男
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] MODY6と診断された親子例2015
- Author(s)
  間部裕代、遠藤文夫、塩谷真由美、堀川幸男、武田　純
- Organizer
  第49回日本小児内分泌学会　学術集会
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 日本人MODY6の4症例についての検討2015
- Author(s)
  塩谷真由美、堀川幸男、武田　純
- Organizer
  第60回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] SHPノックアウトマウスは肥満抵抗性である2015
- Author(s)
  ウウデレフ、飯塚勝美、丹羽啓之、加藤丈博、土田宏美、堀川幸男、武田純
- Organizer
  第58回日本糖尿病学会何時学術集会
- Place of Presentation
  下関市
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] 日本人MODY6の4症例についての検討2015
- Author(s)
  塩谷真由美、堀川幸男、橋本健一、廣田卓男、諏訪哲也、間部裕代、福嶋　恵、大橋正明、池田富貴、武田　純
- Organizer
  第58回日本糖尿病学会学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] The role of ChREBP in the development of high fat-induced fatty liver.2015
- Author(s)
  Iizuka K, Niwa H, Kato T, Wudelehu W, Tsuchida H, Horikawa Y, Takeda J.
- Organizer
  第75回米国糖尿病学会
- Place of Presentation
  ボストン、米国
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] BLM遺伝子のエクソン1欠損とMODYとの関係についての検討2014
- Author(s)
  塩谷　真由美、堀川　幸男、横山　恵子、川田　純子、土田　宏美、廣田　卓男、諏訪　哲也、武田　純
- Organizer
  第57回　日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] インスリン分泌不全状態におけるグルコース活性化転写因子ChREBPの糖および脂質代謝に対する役割2014
- Author(s)
  飯塚勝美、土田　宏美、呉烏徳勒胡、丹羽啓之、独孤　紅、堀川幸男、武田　純
- Organizer
  第57回　日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 糖尿病モデルマウスにおける血中Osteonectin濃度の検討2014
- Author(s)
  呉烏徳勒胡、飯塚勝美、土田宏美、堀川幸男、武田　純
- Organizer
  第87回　日本内分泌学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 糖尿病モデルマウスにおける血中Osteonectin濃度の検討2014
- Author(s)
  呉烏徳勒胡、飯塚勝美、土田宏美、堀川幸男、武田　純
- Organizer
  第87回　日本内分泌学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] 肥満合併症におけるLRH-1の役割　-LRH-1ヘテロノックアウトマウスを用いた検討-2014
- Author(s)
  服部泰輔、飯塚勝美、堀川幸男、武田　純
- Organizer
  第87回　日本内分泌学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 肥満糖尿病病態におけるliraglutideの血中adipokine濃度への効果2014
- Author(s)
  丹羽啓之、飯塚勝美、独孤　紅、土田宏美、加藤丈博、服部泰輔、呉烏徳勒胡、諏訪哲也、堀川幸男、武田　純
- Organizer
  第87回　日本内分泌学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 高脂肪負荷LRH-1ヘテロノックアウトマウスの行動学的解析2014
- Author(s)
  服部泰輔、飯塚勝美、堀川幸男、武田　純
- Organizer
  第57回　日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] 日本人若年糖尿病（MODY）の遺伝素因の解明2014
- Author(s)
  堀川幸男
- Organizer
  第59回日本人類遺伝学会、
- Place of Presentation
  東京
- Year and Date
  2014-10-21
- Invited
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 肥満合併症におけるLRH-1の役割　-LRH-1ヘテロノックアウトマウスを用いた検討-2014
- Author(s)
  服部泰輔、飯塚勝美、堀川幸男、武田　純
- Organizer
  第87回　日本内分泌学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-26293246
[Presentation] 褐色脂肪細胞におけるChREBPとPPARαの機能関連についての検討2013
- Author(s)
  飯塚勝美、呉烏德勒胡、土田宏美、服部泰輔、堀川幸男、斉藤昌之、武田　純
- Organizer
  第56回　日本糖尿病学会　年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] Genetic dissection of early-onset non-type 1 diabetes in Japanese2013
- Author(s)
  Horikawa Y
- Organizer
  Beat Cell Workshop 2013 Kyoto
- Place of Presentation
  Kyoto
- Invited
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 若年糖尿病MODYにおける遺伝的背景と子宮内環境2013
- Author(s)
  堀川幸男
- Organizer
  第29回日本糖尿病・妊娠学会年次学術集会
- Place of Presentation
  岐阜
- Invited
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] LRH-1の肥満病態における意義 -ob/ob LRH-1ダブルノックアウトマウスを用いた解析-2013
- Author(s)
  服部　泰輔、飯塚　勝美、呉　烏徳勒胡、土田　宏美、堀川　幸男、武田　純
- Organizer
  第56回　日本糖尿病学会　年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 全エクソンシークエンスによる新規MODY遺伝子の同定2013
- Author(s)
  堀川幸男
- Organizer
  2013ゲノム支援　拡大班会議
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] ゲノムコピー数多型領域に特化した新規MODY原因遺伝子探索2013
- Author(s)
  堀川幸男、塩谷真由美、武田　純
- Organizer
  第4７回日本小児内分泌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] 血中osteonectin濃度に影響を及ぼす因子の検索2013
- Author(s)
  呉烏徳勒胡、飯塚勝美、土田宏美、服部泰輔、堀川幸男、武田純
- Organizer
  第56回　日本糖尿病学会　年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 2型糖尿病の遺伝素因解明の現状-２型糖尿病の遺伝素因を解剖する2013
- Author(s)
  堀川幸男
- Organizer
  第47回糖尿病学の進歩
- Place of Presentation
  四日市都ホテル
- Invited
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Role of ChREBP and PPARa in the regulation of glucose and lipid metabolism in brown adipocytes2013
- Author(s)
  Iizuka K, Wu W, Hattori T, Horikawa Y, Saito M, Takeda J
- Organizer
  49th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] Role of ChREBP and PPARa in the regulation of glucose and lipid metabolism in brown adipocytes2013
- Author(s)
  Katsumi Iizuka, Wudelehu Wu, Taisuke Hattori, Yukio Horikawa, Masayuki Saito, Jun Takeda
- Organizer
  20. 49th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] Crosstalk between ChREBP and PPARα in brown adipocytes lipid metabolism American Diabetes Association's2013
- Author(s)
  Iizuka K, Wu W, Tsuchida H, Hattori T, Horikawa Y, Saito M, Takeda J
- Organizer
  73th Scientific Sessions
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] MODY患者におけるCopy Number Variantについての検討2013
- Author(s)
  塩谷真由美、堀川幸男、諏訪哲也、廣田卓男、橋本健一、丹羽啓之、冨田礼子、野々　村健太、臼井　綾、武田　純
- Organizer
  第５６回　日本糖尿病学会学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293228
[Presentation] Crosstalk between ChREBP and PPARα in brown adipocytes lipid metabolism2013
- Author(s)
  Katsumi Iizuka, Wudelehu Wu, Hiromi Tsuchida, Taisuke Hattori, Yukio Horikawa1, Masayuki Saito, Jun Takeda
- Organizer
  American Diabetes Association’s 73th Scientific Sessions
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] Glucagon receptor and incretin receptors mRNA expression are inversely, Regulated by glucose through ChREBP activation2012
- Author(s)
  Iizuka K, Tomita R, Wudelehu Wu, Horikawa Y, Takeda J
- Organizer
  9th International Diabetes Federation Western Pacific Region Congress / 4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] GLP-1 アナログ(Liraglutide)導入時における空腹時血糖正常化の有用性膵島機能および adipokine に注目した検討2012
- Author(s)
  飯塚勝美、冨田礼子、水野正巳、丹羽啓之、加藤丈博、諏訪哲也、堀川幸男、武田純
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Long term remission of pulmonary alveolar proteinosisafter successful surgical resection of a Cushing's disease pituitary adenoma2012
- Author(s)
  Kato T, Suwa T, Tomita R, Hirota T,Iizuka K,Horikawa Y,Takeda J
- Organizer
  Endocrine Society's 94th Annual Meeting & Expo 2012
- Place of Presentation
  Houston, Texas, USA
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Glucagon receptor and glucagon-like peptide-1 receptor mRNA expression are inversely regulated by glucose through ChREBP Activation2012
- Author(s)
  Iizuka K, Tomita R, Horikawa Y, Takeda J
- Organizer
  72th Scientific Sessions of American Diabetes Association
- Place of Presentation
  Philadelphia, Pennsylvania, USA
- Year and Date
  2012-06-10
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] 若年発症家族性糖尿病(MODY)の新規原因遺伝子同定の現状2012
- Author(s)
  堀川幸男、塩谷真由美、武田純
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Deletion of the small heterodimer partner gene protects against fatty liver and dyslipidemia, but not obesity and glucose intolerance in C57BL/6J mice fed a high-fat diet2012
- Author(s)
  Iizuka K, Wu W, Tomita R, Tsuchida H, Horikawa Y,Takeda J
- Organizer
  48th EASD Annual Meeting
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] urvey of MODY1-6 in Japanese patients with early-onset oiabetes2012
- Author(s)
  Enya M, Horikawa Y, Takeda J
- Organizer
  9th International Diabetes Federation Western Pacific Region Congress / 4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] LRH-1(Liver Receptor homologue-1) ヘテロノックアウトマウスは摂餌量増加により体重増加をきたす2012
- Author(s)
  服部泰輔、飯塚勝美、呉烏徳勒胡、土田宏美、堀川幸男、武田純
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Glucagon receptor and incretin receptors are inversely regulated by glucose through ChREBP activation2012
- Author(s)
  Iizuka K,Tomita R,Wu W, Horikawa Y, Takeda J
- Organizer
  the 9th IDF-WPR Congress&4th AASD Scientific Meeting
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 岐阜地域における糖尿病統一連携パスの作成と運用2012
- Author(s)
  堀川幸男
- Organizer
  第13回日本クリニカルパス学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] インスリン製剤からの変更時に DPP-IV 阻害剤と GLP-1 アナログの比較を行った一例2012
- Author(s)
  加藤丈博、飯塚勝美、諏訪哲也、堀川幸男、武田純
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Glucagon Receptor and Glucagon-like Peptide-1 Receptor mRNA Expression are Inversely Regulated by Glucose Through ChREBP Activation2012
- Author(s)
  Iizuka K,Tomita R,Horikawa Y,Takeda J
- Organizer
  American Diabetes Association's 72th Scientific Sessions
- Place of Presentation
  Philadelphia, PA
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] グルコース活性化転写因子 ChREBP の転写活性調節におけるグルコース 6 リン酸とキシルロース 5 リン酸の役割2012
- Author(s)
  飯塚勝美、冨田礼子、堀川幸男、武田純
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] 2型糖尿病遺伝素因の解剖2012
- Author(s)
  堀川幸男
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Deletion of the small heterodimer partner gene protects against fatty liver and dyslipidaemia, but not obesity and glucose intolerance in C57BL/6J mice fed a high-fat diet2012
- Author(s)
  Iizuka K, Wudelehu Wu, Tomita R, Tuchida H, Horikawa Y,Takeda J.
- Organizer
  48th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-10-04
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] リラグリチドで食後血糖改善を認めたミトコンドリア糖尿病の 1 例2012
- Author(s)
  加藤丈博、諏訪哲也、水野正巳、服部泰輔、冨田礼子、丹羽啓之、橋本健一、廣田卓男、塩谷真由美、川地慎一、飯塚勝美、堀川幸男、山本眞由美、武田純
- Organizer
  第21回臨床内分泌代謝 Update
- Place of Presentation
  浜松
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] インスリン+シタグリプチン併用療法が有効であった3症例-膵島機能に注目した解析2012
- Author(s)
  橋本健一、飯塚勝美、諏訪哲也、堀川幸男、武田純
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] 日本人若年発症家族性糖尿病(MODY)の新規原因遺伝子探索2012
- Author(s)
  堀川幸男、塩谷真由美、武田純
- Organizer
  第46回日本小児内分泌学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2012-09-28
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] 日本人若年発症糖尿病患者における既知 MODY 遺伝子異常の調査2012
- Author(s)
  塩谷真由美、堀川幸男、土田宏美、飯塚勝美、武田純
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] ステロイド糖尿病にリラグルチド投与が有効であった一例2012
- Author(s)
  水野正巳、飯塚勝美、冨田礼子、諏訪哲也、堀川幸男、武田純
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] 膵島トランスクリプトーム解析による血管合併症関連液性因子の網羅的解析2011
- Author(s)
  堀川幸男
- Organizer
  第26回日本糖尿病合併症学会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Role of glucose-6-phosphate in the regulation of glucose stimulated gene expression in the pancreatic beta cell line INS-1E2011
- Author(s)
  Iizuka K,Tomita R,Horikawa Y,Takeda J
- Organizer
  47th EASD Annual Meeting
- Place of Presentation
  Lisbon, Portugal
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 当院にて経験したインスリン抗体陽性糖尿病4症例の検討2011
- Author(s)
  冨田礼子、飯塚勝美, 諏訪哲也、堀川幸男、武田純
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 脂肪合成遺伝子発現調節機構におけるグルコース感受性転写因子ChREBPと時計遺伝子Klf-10の機能連関に関する検討2011
- Author(s)
  飯塚勝美、堀川幸男、土田宏美, 冨田礼子、服部泰輔、塩谷真由美, 武田純
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] グルコース活性化転写因子ChREBPに注目した時計関連遺伝子KLF10遺伝子のグルコース誘導性発現調節機構の解明2011
- Author(s)
  飯塚勝美、堀川幸男、土田宏美, 服部泰輔、冨田礼子、塩谷真由美, 諏訪哲也、武田純
- Organizer
  第84回日本内分泌学会年次学術集会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] (ワークショップ血糖管理・β細胞)GLP-1アナログ導入時の空腹血糖正常2011
- Author(s)
  飯塚勝美、冨田礼子、堀川幸男、武田純
- Organizer
  日本糖尿病合併症学会年次学術集会
- Place of Presentation
  埼玉県さいたま市
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] グルコース感受性転写因子ChREBPに注目した膵島におけるグルコース依存性遺伝子発現調節機構の解明2011
- Author(s)
  西村英尚、飯塚勝美、冨田礼子, 堀川幸男、武田純
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] The Genetics of Thpe 2 Diabetes : What have we Learned from GWAS? What is Next?2011
- Author(s)
  Y.Horikawa
- Organizer
  Japanese-Danish Kick-off Workshop "Molecular Diabetology"
- Place of Presentation
  神戸
- Year and Date
  2011-03-08
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Rat Krueppel-Like Factor 10 (Klf-10) Gene Expression Is Regulated by the Carbohydrate Response Element Binding Protein ChREBP in Primary Rat Hepatocytes2011
- Author(s)
  Iizuka K, Horikawa Y,Tomita R,Suwa T,Takeda J
- Organizer
  American Diabetes Association's 71st Scientific Sessions
- Place of Presentation
  San Diego, California
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] Molecular dissection of early-onset type 2 diabetes in Japanese2011
- Author(s)
  Y.Horikawa
- Organizer
  The 16^<th> Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  千葉
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22390184
[Presentation] Role of glucose-6-phosphate in regulation of glucose-stimulated gene expression in the pancreatic beta cell line INS-1E2011
- Author(s)
  Iizuka K, Tomita R, Horikawa Y, Takeda J
- Organizer
  47^<th> annual Meeting of the Eurpean Association for the Study of Diabetes (EASD)
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 高脂肪食負荷Liver Receptor Homolog1 (LRH_1)ヘテロノックアウトマウスの代謝学的解析2011
- Author(s)
  服部泰輔、飯塚勝美、堀川幸男
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] Rat Krueppel like factor 10 (Klf-10) gene expression is regulated by the carbohy drate response element binding protein ChREBP in primary rat hepatocytes2011
- Author(s)
  Iizuka K, Horikawa Y, Tomita R, Suwa T, Takeda J
- Organizer
  71th Scientific sessions of American Diabetes Association (ADA)
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2011-06-26
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] グルコース感性性転写因子ChREBPと結合する転写因子Mlxの機能解析2010
- Author(s)
  飯塚勝美, 堀川幸男, 武田純
- Organizer
  第13回日本病態栄養学会年次学術集会
- Place of Presentation
  京都府京都市
- Year and Date
  2010-01-10
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] グルコース感受性転写因子ChREBPと結合する転写因子Mlxの機能解析2010
- Author(s)
  飯塚勝美, 堀川幸男, 武田純
- Organizer
  第12回日本病態栄養学会年次学術集会
- Year and Date
  2010-01-10
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] Fibroblast growth factor 21(FGF21)はラット初代肝細胞においてグルコース活性化転写因子ChREBPにより誘導される2010
- Author(s)
  飯塚勝美、堀川幸男、服部泰輔、青松元昭、塩谷真由美、土田宏美、陳桂英、武田純
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] α-グルコシダーゼ阻害薬とDPP4阻害薬によるCombination Therapy2010
- Author(s)
  堀川幸男、塩谷真由美、川地慎一、飯塚勝美、諏訪哲也、武田純
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 2型糖尿病発症におけるインクレチン関連遺伝子多型の影響について2010
- Author(s)
  塩谷真由美、堀川幸男、飯塚勝美、武田純
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22590973
[Presentation] 転写因子Mlxの肝糖質脂質代謝調節における役割2009
- Author(s)
  飯塚勝美, 堀川幸男, 武田純
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] ChREBPとDEC1/BHLHB2は脂肪合成系酵素の発現調節においてフィードバックループを形成する2009
- Author(s)
  飯塚勝美, 堀川幸男, 武田純
- Organizer
  第82回日本内分泌学会年次学術集会
- Place of Presentation
  前橋
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 脂肪合成系酵素発現調節における時計遺伝子DEC1の役割2009
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第12回日本病態栄養学会ワークショップ
- Place of Presentation
  京都
- Year and Date
  2009-01-11
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 転写因子Mlxの肝糖質脂質代謝調節における役割2009
- Author(s)
  飯塚勝美, 堀川幸男, 武田純
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] ChREBPとDEC1/BHLHB2は脂肪合成系酵素の発現調節においてフィードバックループを形成する2009
- Author(s)
  飯塚勝美, 堀川幸男, 武田純
- Organizer
  第82回日本内分泌学会年次学術集会
- Place of Presentation
  群馬県前橋市
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 日本人2型糖尿病患者におけるMODY7遺伝子(KLF11)の検討2008
- Author(s)
  黒田英嗣, 堀川幸男, 塩谷真由美, 飯塚勝美, 武田純
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] グルコース感受性転写因子ChREBPの肥満糖尿病における役割2008
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第22回日本肥満糖尿病動物学会ワークショップ
- Place of Presentation
  東京
- Year and Date
  2008-02-09
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] グルコース感受性転写因子ChREBPの肥満糖尿病病態における役割2008
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第22回日本糖尿病学会年次学術集会(ワークショップ)
- Place of Presentation
  東京
- Year and Date
  2008-02-09
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 転写抑制因子Bhlhb2はグルコースセンサーChREBPの標的遺伝子である2008
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 視床下部グルココルチコイド反応性遺伝子の大規模解2008
- Author(s)
  佐藤大仁, 堀川幸男, 飯塚勝美, 桜井敬子, 田中毅, 志原伸幸大嶋昭彦, 武田純, 三國雅彦
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] ラット膵島発現分泌蛋白の探索2007
- Author(s)
  志原伸幸, 堀川幸男, 飯塚勝美, 武田純
- Organizer
  第50回日本糖尿病学会総会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 肝臓特異的ChREBP過剰発現マウスの解析2007
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第50回日本糖尿病学会年次学術集会(口演)
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] ラット膵島発現分泌蛋白の探索2007
- Author(s)
  志原伸幸堀川幸男飯塚勝癸武田純
- Organizer
  第50回日本糖尿病学会年次学術集会(口演)
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 肝臓特異的ChREBP過剰発現マウスの解析2007
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第50回日本糖尿病学会総会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] グルコースセンサーChREBPに注目した肥満糖尿病病態の解析2007
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第50回日本糖尿病学会年次学術集会(シンポジウム)
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] グルコースセンサーChREBPに注目した肥満糖尿病病態の解析2007
- Author(s)
  飯塚勝美, 堀川幸男
- Organizer
  第50回日本糖尿病学会総会年次学術集会シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] カルパイン10はグルコース応答性インスリン分泌に関与する2007
- Author(s)
  飯塚勝美, 志原伸幸, 堀川幸男
- Organizer
  第80回日本内分泌学会年次学術集会(口演)
- Place of Presentation
  東京
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 視床下部グルココルチコイド感受性遺伝子の網羅的検索2007
- Author(s)
  佐藤大仁, 堀川幸男, 飯塚勝美, 志原伸幸, 大嶋明彦, 武田純, 三国雅彦
- Organizer
  第80回日本内分泌学会年次学術集会(口演)
- Place of Presentation
  東京
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] カルパイン10はグルコース応答性インスリン分泌に関与する2007
- Author(s)
  飯塚勝美, 志原伸幸, 堀川幸男
- Organizer
  第80回日本内分泌学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] 視床下部グルココルチコイド感受性遺伝子の網羅的検索2007
- Author(s)
  佐藤大仁, 堀川幸男, 飯塚勝美, 志原伸幸, 大嶋昭彦, 武田純, 三國雅彦
- Organizer
  第80回日本内分泌学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19591035
[Presentation] The role of ChREBP in the development of high fat diet induced fatty liver
- Author(s)
  Katsumi Iizuka, Hiroyuki Niwa, Takehiro Kato, Hiromi Tsuchida, Yukio Horikawa, Jun Takeda
- Organizer
  American Diabetes Association 75th Scientific sessions
- Place of Presentation
  米国マサチューセッツ州ボストン
- Year and Date
  2015-06-05 – 2015-06-09
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] Deletion of ChREBP Gene in Mice Did Not Improve Glucose Intolerance in Insulin-Deficient State
- Author(s)
  KATSUMI IIZUKA, WUDELEHU WU, HIROYUKI NIWA, HIROMI TSUCHIDA, KOU DOKUKO, YUKIO HORIKAWA, JUN TAKEDA
- Organizer
  American Diabetes Association 74th Scientific sessions
- Place of Presentation
  米国カルフォルニア州サンフランシスコ
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] 高脂肪食によって惹起される脂肪肝病態でのChREBPの役割
- Author(s)
  丹羽啓之, 飯塚勝美, 加藤丈博, 土田宏美, 呉烏徳勒胡, 堀川幸男, 武田純
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  山口県下関市
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] インスリン分泌不全状態におけるグルコース活性化転写因子ChREBPの糖および脂質代謝に対する役割
- Author(s)
  飯塚勝美, 土田宏美, 呉烏徳勒胡, 丹羽啓之, 独孤紅, 堀川幸男, 武田純
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26500005
[Presentation] ミグリトールによる小腸ＣｈＲＥＢＰ標的遺伝子の発現変化に関する検討
- Author(s)
  加藤丈博，飯塚勝美，呉烏徳勒胡，土田宏美，丹羽啓之，堀川幸男，北村忠弘，武田純
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  山口県下関市
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-26500005
[]

1. TAKEDA Jun (40270855)

# of Collaborated Projects: 14 results

# of Collaborated Products: 134 results
2. IIZUKA Katsumi (40431712)

# of Collaborated Projects: 10 results

# of Collaborated Products: 123 results
3. TOMURA Hideaki (70217553)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 矢部大介 (60378643)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
5. HOSOMICHI Kazuyoshi (50420948)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. 正公枝 (40201561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 塩谷真由美 (10293565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 室谷健太 (10626443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松本晃太郎 (60932217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 矢部富雄 (70356260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 高橋佳大 (60950045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KATO Takehiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. TAKAO Ken

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. NIWA Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
15. WU Wudelehu

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 井ノ上逸郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 西郡秀和

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 西郡俊絵

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 井ノ上逸朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 村上隆亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Horikawa Yukio 堀川 幸男

HORIKAWA Yukio 堀川 幸男

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Genetic dissection of rare MODY by multidisciplinary functional genomicsPrincipal Investigator

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Identification of the molecular cause of MODY in Japanese by deep sequencing of the regions of the MODY-specific deletion type of Copy Number VariantPrincipal Investigator

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Analysis of inslin secretion insufficiency in type 2 diabetes due to calpain 10 dysfunctionPrincipal Investigator

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Establishment of detection tool for risk of type 2 diabetes using mice of 'digenic' form of type 2 diabetesPrincipal Investigator

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Horikawa Yukio 堀川幸男

HORIKAWA Yukio 堀川幸男

[Book] 月刊糖尿病. 堀川幸男(編集)　遺伝子異常と糖尿病　MODY1-62020

[Book] DM Ensemble　糖尿病性腎症重症化予防プログラムと糖尿病連携手帳の活用.2020

[Book] 岐阜県医師会医学雑誌　岐阜県下における「糖尿病連携手帳」の実態調査.2020

[Book] 特集糖尿病診療update : 最新の診断と治療　糖尿病に関する教育と支援2020

[Book] 糖尿病単一遺伝子異常による糖尿病-MODY2019