Inoue Hiroshi 井上博

… Alternative Names

井上博イノウエヒロシ

INOUE Hiroshi 井上博

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Researcher Number	10330143
Other IDs
Affiliation (Current)	2025: 大阪歯科大学, 歯学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 大阪歯科大学, 歯学部, 講師 2012 – 2014: 大阪歯科大学, 歯学部, 講師 2009 – 2010: Osaka Dental University, 歯学部, 講師 2008: 大阪歯科大, 歯学部, 講師 2004 – 2006: 大阪歯科大学, 歯学部, 助手 2001 – 2002: 大阪歯科大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学) Except Principal Investigator Social dentistry / Periodontal dentistry
Keywords	Principal Investigator NK細胞 / シグナル伝達 / CD2 / IL-17 / ケモカイン / MMP / 細胞内顆粒 / 細胞殺傷能 / 免疫学 / raft / LAT … More Except Principal Investigator … More 歯学 / シグナル伝達 / p38MAP kinase / TIMP-1 / コラーゲン分解能 / 歯肉線維芽細胞 / 歯周再生 / p38 MAP kinase / bFGF / ｂFGF / TIMP / 慢性歯周炎 / メタボリックシンドローム / 内科 / メタボリックシンドローム / 歯周病 Less

Effect of p38 MAPK family new function in periodontitis suppression mechanism
- Principal Investigator
  
  Goda Seiiji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Osaka Dental University
  Kanagawa Dental College
The role of IL-17 on NK cell activation.- Analysis for elucidation of inflammation mechanisms.-Principal Investigator
- Principal Investigator
  
  INOUE Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka Dental University
Analysis for the mechanisms of NK cell invasion into the connective tissue which is elucidate for mechanism of inflammationPrincipal Investigator
- Principal Investigator
  
  INOUE Hiroshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka Dental University
Studies on the etiological relationship between periodontitis and life-style related diseases
- Principal Investigator
  
  DOMAE Naochika
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka Dental University
NK細胞における細胞傷害能を活性化するシグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  井上博
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka Dental University
NK細胞におけるCD2分子を介したシグナル伝達機構の解析(新たな歯周病治療法開発のための基礎的検討)Principal Investigator
- Principal Investigator
  
  井上博
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Osaka Dental University

All 2019 2018 2017 2015 2014 2013 2012 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Effect of bisphenol A exposure on spontaneous behavior using the elevated plus maze test.2019
- Author(s)
  Fujimoto T, Inoue H, Hirano S, Goda S.
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 53(2) Pages: 187-192
- NAID
  130007790271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K12027
[Journal Article] Coordinated effect of IL-17A and IL-27 on osteoclast differentiation of RANKL-stimulated RAW264.7 cells.2015
- Author(s)
  Ohashi M, Inoue H, Nishikawa Y, Matsumoto N.
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 49 Pages: 61-68
- NAID
  110009942790
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] IL-17A inhibits osteoclast differentiation of RANKL-stimulated RAW 264.7 cells by suppressing JNK phosphorylation and c-Fos expression.2014
- Author(s)
  Nosaka K, Inoue H, Hirano S, Uchihashi K, Nishikawa Y.
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 48 Pages: 117-123
- NAID
  110009865345
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] Enamel matrix derivative protein enhances production of matrixmetalloproteinase-2 by osteoblasts.2014
- Author(s)
  Goda S, Inoue H, Takeuchi O, Ujii Y, Domae E, Ikeo T.
- Journal Title
  
  BMC Oral Health
  
  Volume: 14 Pages: 85-93
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] Alpha 2 integrin associates with MMP-1 on human CXCL8-activate NK cells.2014
- Author(s)
  Goda S, Inoue H, Domae E, Yoshikawa Y, Tamura I, Kamada A, Nishikawa Y, Ikeo T.
- Journal Title
  
  J Oral Tissue Engin
  
  Volume: 11 Pages: 213-219
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] Sevoflurane confers additive cardioprotection to ethanol preconditioning associated with enhanced phosphorylation of glycogen synthase kinase-3β and inhibition of mitochondrial permeability transition pore opening.2013
- Author(s)
  Onishi A, Miyamae M, Inoue H, Kaneda K, Okusa C, Inamura Y, Shiomi M, Koshinuma S, Momota Y, Figueredo V.M.
- Journal Title
  
  J Cardiothorac Vasc Anesth
  
  Volume: 27 Pages: 916-924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] Matrix metalloproteinase-1 produced by human CXCL8-activated NK cells.2013
- Author(s)
  Goda S, Inoue H, Domae E, Kagawa M, Hosoyama Y, Matsumoto N, Nishiyama Y, Ikeo T.
- Journal Title
  
  J Oral Tissue Engin
  
  Volume: 11 Pages: 163-171
- NAID
  130004941109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] Ablation of rat substantia nigra may provide a good acute model of Parkinson’s disease for stem cell transplantation.2013
- Author(s)
  Hirano S, Ohashi M, Kakihara R, Suwabe T, Fujimoto T, Inoue H, Uchihashi K, Nishikawa Y.
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 47 Pages: 11-19
- NAID
  110009603274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] Mechanisms of NK cell activation stimulated by CD2; granzyme B is released by CD2 crosslinking-stimulation on NK92 cells.2012
- Author(s)
  Inoue H
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 46 Pages: 229-235
- NAID
  110009553531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592853
[Journal Article] Matrix metalloproteinase 1 produced by CXCL12 stimulation on NK92 cells.2009
- Author(s)
  INOUE H, GODA S, DOMAE N, NOSAKA K, NAKAI M, UCHIHASHI K, NISHIKAWA Y.
- Journal Title
  
  J Osaka Dent Univ 43
  
  Pages: 163-167
- NAID
  110007386259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791833
[Journal Article] Enamel matrix derivative protein stimulated wound healing via phosphoinositide 3-Kinase.2009
- Author(s)
  GODA S, KANESHITA Y, INOUE H, IKEO T, IIDA J, DOMAE N.
- Journal Title
  
  J Periodontol 80
  
  Pages: 1631-1637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791833
[Journal Article] Matrix metalloproteinase 1 produced by CXCL12 stimulation on NK92 cells2009
- Author(s)
  INOUE H
- Journal Title
  
  J Osaka Dent Univ 43
  
  Pages: 163-167
- NAID
  110007386259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791833
[Journal Article] Emdogain stimulates matrix degra dation by osteoblasts2008
- Author(s)
  GODA S, INOUE H, KANESHITA Y, NAGANO Y, IKEO T, IIDA J, DOMAE N
- Journal Title
  
  J Dent Res 87
  
  Pages: 782-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] Effect of S-PRG filler eluate on MAP kinase-family phosphorylation of human gingival fibroblasts.2018
- Author(s)
  Inoue H, Goda S, Nishikawa.
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K12027
[Presentation] S-PRGフィラー溶出液がヒト歯肉線維芽細胞のMatrix metalloproteinase産生に及ぼす影響．2017
- Author(s)
  井上　博，合田征司，西川泰央．
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K12027
[Presentation] IL-17A inhibits osteoclast differentiation of RANKL-stimulated RAW 264.7 cells2015
- Author(s)
  Inoue H, Uchihashi K, Nishikawa Y.
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会　合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] RANKL刺激によるRAW264.7細胞の破骨細胞分化におけるIL-17AとIL-27の協調効果．2014
- Author(s)
  大橋　百加、井上　博、西川　泰央、松本尚之．
- Organizer
  第545回大阪歯科学会例会
- Place of Presentation
  大阪歯科大学（枚方市）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] IL-17AはJNKリン酸化とc-fos発現を抑えることによりRANKL刺激されたRAW264.7細胞の破骨細胞分化を抑制する．2014
- Author(s)
  野阪　興、井上　博、平野俊一朗、内橋賢二、西川泰央
- Organizer
  第544回大阪歯科学会例会
- Place of Presentation
  大阪歯科大学（枚方市）
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] RAW264.7細胞の破骨細胞分化においてIL-17A刺激がJNKとc-fosに及ぼす影響．2014
- Author(s)
  井上　博、内橋賢二、西川泰央．
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場（福岡市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] RAW264.7細胞の破骨細胞分化におけるIL-17Aの直接的影響．2013
- Author(s)
  大橋　百加，角倉　紗恵子，井上　博，西川　泰央，松本　尚之．
- Organizer
  第72回日本矯正歯科学会大会
- Place of Presentation
  松本市総合体育館（松本市）
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] IL-17AがNK細胞の細胞増殖能および細胞傷害能に及ぼす影響について．2012
- Author(s)
  井上　博
- Organizer
  第22回日本歯科医学会総会
- Place of Presentation
  大阪国際会議場（大阪市）
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] 破骨細胞前駆細胞におけるIL-17の影響.2010
- Author(s)
  角倉紗恵子, 井上博, 西川泰央, 松本尚之.
- Organizer
  第69回日本矯正歯科学会大会
- Place of Presentation
  横浜市
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] C-reactive protein can increase chemotaxis of monocytes through promoting CD192 expression.2010
- Author(s)
  MengShu, ZhaoLei, WuYa-fei, 方一如, 藤本哲也, 成瀬真弓, 平野俊一朗, 井上博, 内橋賢二, 西川泰央.
- Organizer
  第52回歯科基礎医学会
- Place of Presentation
  東京都
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] NK細胞におけるIL-17の影響.2010
- Author(s)
  井上博, 藤本哲也, 成瀬真弓, 平野俊一朗, 内橋賢二, 西川泰央.
- Organizer
  第52回歯科基礎医学会
- Place of Presentation
  東京都
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] NK細胞におけるIL-17の影響2010
- Author(s)
  井上博
- Organizer
  第52回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] ボツリヌストキシンAの導管注入によるラット唾液腺のnNOSの免疫反応に対する影響.2010
- Author(s)
  内橋賢二, 成瀬真弓, 藤本哲也, 平野俊一朗, 井上博, 西川泰央.
- Organizer
  第52回歯科基礎医学会
- Place of Presentation
  東京都
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] CXCL8刺激NK細胞におけるI型コラーゲンに対する浸潤と遊走について2009
- Author(s)
  井上博
- Organizer
  第51回日本歯科基礎医学会学術大会・総会
- Place of Presentation
  朱鷺メッセ(新潟県)
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] CXCL12刺激によるNK細胞のI型コラーゲンに対する浸潤と分解について.2009
- Author(s)
  中島紗恵子、井上博、西川泰央、松本尚之.
- Organizer
  第68回日本矯正歯科学会大会
- Place of Presentation
  福岡市
- Year and Date
  2009-11-18
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] Expression of matrix metalloproteinase-1 on NK cells stimulated by CXCL8 and CXCL122009
- Author(s)
  井上博
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] CXCL8刺激NK細胞におけるI型コラーゲンに対する浸潤と遊走について.2009
- Author(s)
  井上博, 合田征司, 池尾隆, 堂前尚親, 西川泰央.
- Organizer
  第51回歯科基礎医学会
- Place of Presentation
  新潟市
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] Expression of matrix metalloproteinase-1 on NK cells stimulated by CXCL8 and CXCL12.2009
- Author(s)
  INOUE H, DOMAE N, NISHIKAWA Y.
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都市
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] 破骨細胞分化におけるSMS1の影響について2009
- Author(s)
  井上博
- Organizer
  ハイテク・リサーチ・センター整備事業「歯周病に対する戦略的研究」第1回研究成果報告会
- Place of Presentation
  大阪歯科大学(大阪府)
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21791833
[Presentation] ケモカイン刺激NK細胞におけるMatrix metalloproteinase-1の発現について2008
- Author(s)
  井上博,合田征司,池尾隆, 堂前尚親,西川泰央
- Organizer
  第50回日本歯科基礎医学会
- Place of Presentation
  東京都
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] NK細胞のI型コラーゲンに対する浸潤と分解について2008
- Author(s)
  井上博,合田征司,金下祐己, 松本尚之,池尾隆,堂前尚親
- Organizer
  日本歯周病学会2008春季学術大会(第51回)
- Place of Presentation
  埼玉県
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] Matrix metallo- proteinase-1(MMP-1)andα2-integrin on the surface of NK3.3 cells stimulated by CXCL122008
- Author(s)
  INOUE H, DOMAE N, NISHIKAWA Y
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京都
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] ケモカイン刺激NK細胞におけるMatrix metalloproteinase-1の発現について2008
- Author(s)
  井上博
- Organizer
  第50回日本歯科基礎医学会
- Place of Presentation
  東京都
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] CXCL12刺激NK 細胞における細胞膜上のMatrix metalloproteinase-1 (MMP-1)とα2- Integrinの局在について2007
- Author(s)
  井上博,合田征司,池尾隆,堂前尚親,西川泰央
- Organizer
  .第49回日本歯科基礎医学会
- Place of Presentation
  北海道
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] CXCL12刺激NK細胞における細胞膜上のMatrix metalloproteinase-1 (MMP-1)とα2-Integrinの局在について2007
- Author(s)
  井上博
- Organizer
  第49回日本歯科基礎医学会
- Place of Presentation
  北海道
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] RAW264.7細胞の破骨細胞分化に及ぼすIL-17Aの影響
- Author(s)
  井上　博，堂前英資，合田　征司，内橋　賢二，西川　泰央．
- Organizer
  第55回歯科基礎医学会学術大会・総会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] RAW264.7細胞の破骨細胞分化におけるIL-17AとIL-27の協調効果について．
- Author(s)
  大橋　百加、井上　博、西川　泰央、松本尚之．
- Organizer
  第73回日本矯正歯科学会大会
- Place of Presentation
  幕張メッセ（千葉市）
- Year and Date
  2014-10-21 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] CD2架橋刺激はNK92細胞からのグランザイムB放出を増強する.
- Author(s)
  井上　博
- Organizer
  第54回歯科基礎医学会学術大会・総会
- Place of Presentation
  奥羽大学（郡山市）
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] Release of granzyme B from NK92 cells which was crosslinking-stimulated by CD2.
- Author(s)
  Hiroshi Inoue
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-24592853
[Presentation] RANKL-induced osteoclast differentiation on RAW264.7 cells is suppressed by the direct effect of IL-17A.
- Author(s)
  Inoue H, Uchihashi K, Nishikawa Y.
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島市）
- Data Source
  KAKENHI-PROJECT-24592853

1. GODA Seiji (70351476)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. DOMAE Naochika (60115889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. UEDA Masatoshi (00067117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MASAKI Kambara (90103085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAGANO Yutaka (80228048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. MIYAMAE Masami (20298821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAWAI Hirofumi (40298823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 三宅達郎 (40200141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤武則 (40638904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Inoue Hiroshi 井上 博

井上 博 イノウエ ヒロシ

INOUE Hiroshi 井上 博

Research Projects

Research Products

Co-Researchers

Effect of p38 MAPK family new function in periodontitis suppression mechanism

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The role of IL-17 on NK cell activation.- Analysis for elucidation of inflammation mechanisms.-Principal Investigator

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Analysis for the mechanisms of NK cell invasion into the connective tissue which is elucidate for mechanism of inflammationPrincipal Investigator

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Studies on the etiological relationship between periodontitis and life-style related diseases

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NK細胞における細胞傷害能を活性化するシグナル伝達機構の解析Principal Investigator

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NK細胞におけるCD2分子を介したシグナル伝達機構の解析(新たな歯周病治療法開発のための基礎的検討)Principal Investigator

Principal Investigator

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Research Institution

[Journal Article] Effect of bisphenol A exposure on spontaneous behavior using the elevated plus maze test.2019

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NAID

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[Journal Article] Coordinated effect of IL-17A and IL-27 on osteoclast differentiation of RANKL-stimulated RAW264.7 cells.2015

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NAID

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[Journal Article] IL-17A inhibits osteoclast differentiation of RANKL-stimulated RAW 264.7 cells by suppressing JNK phosphorylation and c-Fos expression.2014

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NAID

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[Journal Article] Enamel matrix derivative protein enhances production of matrixmetalloproteinase-2 by osteoblasts.2014

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[Journal Article] Alpha 2 integrin associates with MMP-1 on human CXCL8-activate NK cells.2014

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[Journal Article] Sevoflurane confers additive cardioprotection to ethanol preconditioning associated with enhanced phosphorylation of glycogen synthase kinase-3β and inhibition of mitochondrial permeability transition pore opening.2013

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[Journal Article] Matrix metalloproteinase-1 produced by human CXCL8-activated NK cells.2013

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NAID

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[Journal Article] Ablation of rat substantia nigra may provide a good acute model of Parkinson’s disease for stem cell transplantation.2013

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NAID

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[Journal Article] Mechanisms of NK cell activation stimulated by CD2; granzyme B is released by CD2 crosslinking-stimulation on NK92 cells.2012

Inoue Hiroshi 井上博

井上博イノウエヒロシ

INOUE Hiroshi 井上博