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EGAWA Katsuya  江川 克哉

ORCIDConnect your ORCID iD *help
Researcher Number 10335169
Affiliation (based on the past Project Information) *help 2002 – 2004: 滋賀医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Metabolomics
Except Principal Investigator
Metabolomics / Biological Sciences
Keywords
Principal Investigator
IRS-1 degradation / PP2C / adenovirus / PLCg / アデノウイルス / PLCγ
Except Principal Investigator
PP2A / SREBP-1 / PTP1B / Protein phosphatase … More / insulin resistance / Protein-tyrosine phosphatase / プロテインホスファターゼ / インスリン抵抗性 / チロシンホスファターゼ / Akt / PI3キナーゼ / 脂肪分化 / Small T antigen / PP2C / Glucose transporter 4 / Tumor Necrosis Factor α / adiponectin / Grb2 associated binder-1 / atypical Protein Kinase C / Phospholipase C / TFAP2B Less
  • Research Projects

    (3 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (3 People)
  •  脂肪細胞におけるインスリン感受性獲得の分子機構と肥大化誘導分子の同定

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shiga University of Medical Science
  •  Organ specificity of insulin resistance induced by Protein-tyrosine phosphatase

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  Molecular mechanism of IRS-1 degradation by PLGγ and PP2CPrincipal Investigator

    • Principal Investigator
      EGAWA Katsuya
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science

All 2006 2005 2004 2003 2002

All Journal Article

  • [Journal Article] Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.2006

    • Author(s)
      Tsukada S, Tanaka Y, Maegawa H, et al.
    • Journal Title

      Molecular Endocrinology (in press)

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] The transcription factor AP-2β causes cell enlargement and insulin resistance in 3T3-L1 adipocytes.2006

    • Author(s)
      Tao Y, Maegawa H, et al.
    • Journal Title

      Endocrinology (in press)

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] Regulation of ATP-sensitive potassium-channel subunit Kir6.2 expression in rat intestinal insulin-production progenitor cells.2005

    • Author(s)
      Hashimoto T, Nakamura T, Maegawa H, Nishio Y, Egawa K, Kashiwagi A.
    • Journal Title

      J Biol Chem 280

      Pages: 1893-1900

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Regulation of ATP-sensitive potassium-channel subunit Kir6.2 expression in rat intestinal insulin-production progenitor cells.2005

    • Author(s)
      Hashimoto T, Nakamura T, Maegawa H, Nishio Y, Egawa K, et al.
    • Journal Title

      J Biol Chem 280

      Pages: 1893-1900

    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004

    • Author(s)
      Shi K, Egawa_K, Maegawa H, et al.
    • Journal Title

      J Biochem (Tokyo) 136

      Pages: 89-96

    • NAID

      10016200944

    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004

    • Author(s)
      Shi K, Egawa K, Maegawa H, Nakamura T, Ugi S, Nishio Y, Kashiwagi A.
    • Journal Title

      J Biochem (Tokyo) 136

      Pages: 89-96

    • NAID

      10016200944

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein phosphatase 2C α as a positive regulator if insulin sensitivity through direct activation of phospphatidylinointol 3-kinase in 3T3-L1 adipocytes2004

    • Author(s)
      Yoshizaki T, Maegawa H, et al.
    • Journal Title

      J Biol Chem 279

      Pages: 22715-22726

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes.2004

    • Author(s)
      Ugi S, Imamura T, Maegawa H, et al.
    • Journal Title

      Mol Cell Biol 24

      Pages: 8778-8789

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.2004

    • Author(s)
      Yoshizaki T, Maegawa H, Egawa K, et al.
    • Journal Title

      J Biol Chem 279

      Pages: 22715-22726

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.2004

    • Author(s)
      Yoshizaki T, Maegawa H, Egawa K, Ugi S, Nishio Y, Imamura T, Kobayashi T, Tamura S, Olefsky JM, Kashiwagi A.
    • Journal Title

      J Biol Chem 279

      Pages: 22715-22726

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein phosphatase 2A negatively regulates insulin's metabolic signaling psthway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.2004

    • Author(s)
      Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagu A, Olefsky JM.
    • Journal Title

      Mol Cell Biol 24

      Pages: 8778-8789

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.2004

    • Author(s)
      Ugi S, Imamura T, Maegawa H, Egawa K, et al.
    • Journal Title

      Mol Cell Biol 24

      Pages: 8778-8789

    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004

    • Author(s)
      Shi K, Egawa K, Maegawa H, et al.
    • Journal Title

      J Biochem (Tokyo) 136

      Pages: 89-96

    • NAID

      10016200944

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression.2003

    • Author(s)
      Shimizu S, Ugi S, Maegawa H, Egawa K, et al.
    • Journal Title

      J Biol Chem 278

      Pages: 43095-43101

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression.2003

    • Author(s)
      Shimizu S, Ugi S, Maegawa H, Egawa K, Nishio Y, Yoshizaki T, Shi K, Nagai Y, Morino K, Nemoto K, Nakamura T, Bryer-Ash M, Kashiwagi A.
    • Journal Title

      J Biol Chem 278

      Pages: 43095-43101

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes.2002

    • Author(s)
      Shimizu S, Maegawa H, Egawa K, et al.
    • Journal Title

      Endocrinology 143

      Pages: 4563-4569

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and Atypical PKC, but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.2002

    • Author(s)
      Egawa K, Maegawa H, Shi K, Nakamura T, Obata T, Yoshizaki T, Morino K, Shimizu S, Nishio Y, Suzuki E, Kashiwagi A.
    • Journal Title

      J Biol Chem 277

      Pages: 38863-38869

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Mechanism for differential effect of protein-tyrosine phosphatase IB on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes.2002

    • Author(s)
      Shimizu S, Maegawa H, Egawa K, Shi K, Bryer-Ash M, Kashiwagi A.
    • Journal Title

      Endocrinology 143

      Pages: 4563-4569

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.2002

    • Author(s)
      Sekine O, Nishio Y, Egawa K, Nakamura T, Maegawa H, Kashiwagi A.
    • Journal Title

      J Biol Chem 277

      Pages: 36631-36639

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical PKC, but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.2002

    • Author(s)
      Egawa K, Maegawa H, Shi K, et al.
    • Journal Title

      J Biol Chem 277

      Pages: 38863-38869

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • [Journal Article] Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells2002

    • Author(s)
      Sekine O, Nishio Y, Egawa K, et al.
    • Journal Title

      J Biol Chem 277

      Pages: 36631-36639

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571089
  • 1.  MAEGAWA Hiroshi (00209363)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 2.  卯木 智 (20378483)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  前田 士郎 (50314159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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