EGAWA Katsuya 江川克哉

Researcher Number	10335169
Affiliation (based on the past Project Information) *help	2002 – 2004: 滋賀医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Metabolomics Except Principal Investigator Metabolomics / Biological Sciences
Keywords	Principal Investigator IRS-1 degradation / PP2C / adenovirus / PLCg / アデノウイルス / PLCγ Except Principal Investigator PP2A / SREBP-1 / PTP1B / Protein phosphatase … More / insulin resistance / Protein-tyrosine phosphatase / プロテインホスファターゼ / インスリン抵抗性 / チロシンホスファターゼ / Akt / PI3キナーゼ / 脂肪分化 / Small T antigen / PP2C / Glucose transporter 4 / Tumor Necrosis Factor α / adiponectin / Grb2 associated binder-1 / atypical Protein Kinase C / Phospholipase C / TFAP2B Less

脂肪細胞におけるインスリン感受性獲得の分子機構と肥大化誘導分子の同定
- Principal Investigator
  
  MAEGAWA Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Shiga University of Medical Science
Organ specificity of insulin resistance induced by Protein-tyrosine phosphatase
- Principal Investigator
  
  MAEGAWA Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science
Molecular mechanism of IRS-1 degradation by PLGγ and PP2CPrincipal Investigator
- Principal Investigator
  
  EGAWA Katsuya
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science

All 2006 2005 2004 2003 2002

All Journal Article

[Journal Article] Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.2006
- Author(s)
  Tsukada S, Tanaka Y, Maegawa H, et al.
- Journal Title
  
  Molecular Endocrinology (in press)
- Data Source
  KAKENHI-PROJECT-16046211
[Journal Article] The transcription factor AP-2β causes cell enlargement and insulin resistance in 3T3-L1 adipocytes.2006
- Author(s)
  Tao Y, Maegawa H, et al.
- Journal Title
  
  Endocrinology (in press)
- Data Source
  KAKENHI-PROJECT-16046211
[Journal Article] Regulation of ATP-sensitive potassium-channel subunit Kir6.2 expression in rat intestinal insulin-production progenitor cells.2005
- Author(s)
  Hashimoto T, Nakamura T, Maegawa H, Nishio Y, Egawa K, Kashiwagi A.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 1893-1900
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Regulation of ATP-sensitive potassium-channel subunit Kir6.2 expression in rat intestinal insulin-production progenitor cells.2005
- Author(s)
  Hashimoto T, Nakamura T, Maegawa H, Nishio Y, Egawa K, et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 1893-1900
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004
- Author(s)
  Shi K, Egawa_K, Maegawa H, et al.
- Journal Title
  
  J Biochem (Tokyo) 136
  
  Pages: 89-96
- NAID
  10016200944
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004
- Author(s)
  Shi K, Egawa K, Maegawa H, Nakamura T, Ugi S, Nishio Y, Kashiwagi A.
- Journal Title
  
  J Biochem (Tokyo) 136
  
  Pages: 89-96
- NAID
  10016200944
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein phosphatase 2C α as a positive regulator if insulin sensitivity through direct activation of phospphatidylinointol 3-kinase in 3T3-L1 adipocytes2004
- Author(s)
  Yoshizaki T, Maegawa H, et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 22715-22726
- Data Source
  KAKENHI-PROJECT-16046211
[Journal Article] Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes.2004
- Author(s)
  Ugi S, Imamura T, Maegawa H, et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 8778-8789
- Data Source
  KAKENHI-PROJECT-16046211
[Journal Article] Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.2004
- Author(s)
  Yoshizaki T, Maegawa H, Egawa K, et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 22715-22726
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.2004
- Author(s)
  Yoshizaki T, Maegawa H, Egawa K, Ugi S, Nishio Y, Imamura T, Kobayashi T, Tamura S, Olefsky JM, Kashiwagi A.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 22715-22726
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein phosphatase 2A negatively regulates insulin's metabolic signaling psthway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.2004
- Author(s)
  Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagu A, Olefsky JM.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 8778-8789
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.2004
- Author(s)
  Ugi S, Imamura T, Maegawa H, Egawa K, et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 8778-8789
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004
- Author(s)
  Shi K, Egawa K, Maegawa H, et al.
- Journal Title
  
  J Biochem (Tokyo) 136
  
  Pages: 89-96
- NAID
  10016200944
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression.2003
- Author(s)
  Shimizu S, Ugi S, Maegawa H, Egawa K, et al.
- Journal Title
  
  J Biol Chem 278
  
  Pages: 43095-43101
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression.2003
- Author(s)
  Shimizu S, Ugi S, Maegawa H, Egawa K, Nishio Y, Yoshizaki T, Shi K, Nagai Y, Morino K, Nemoto K, Nakamura T, Bryer-Ash M, Kashiwagi A.
- Journal Title
  
  J Biol Chem 278
  
  Pages: 43095-43101
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes.2002
- Author(s)
  Shimizu S, Maegawa H, Egawa K, et al.
- Journal Title
  
  Endocrinology 143
  
  Pages: 4563-4569
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and Atypical PKC, but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.2002
- Author(s)
  Egawa K, Maegawa H, Shi K, Nakamura T, Obata T, Yoshizaki T, Morino K, Shimizu S, Nishio Y, Suzuki E, Kashiwagi A.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 38863-38869
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Mechanism for differential effect of protein-tyrosine phosphatase IB on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes.2002
- Author(s)
  Shimizu S, Maegawa H, Egawa K, Shi K, Bryer-Ash M, Kashiwagi A.
- Journal Title
  
  Endocrinology 143
  
  Pages: 4563-4569
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.2002
- Author(s)
  Sekine O, Nishio Y, Egawa K, Nakamura T, Maegawa H, Kashiwagi A.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 36631-36639
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical PKC, but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.2002
- Author(s)
  Egawa K, Maegawa H, Shi K, et al.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 38863-38869
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571089
[Journal Article] Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells2002
- Author(s)
  Sekine O, Nishio Y, Egawa K, et al.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 36631-36639
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571089

1. MAEGAWA Hiroshi (00209363)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 卯木智 (20378483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 前田士郎 (50314159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

EGAWA Katsuya 江川 克哉

Research Projects

Research Products

Co-Researchers

脂肪細胞におけるインスリン感受性獲得の分子機構と肥大化誘導分子の同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Organ specificity of insulin resistance induced by Protein-tyrosine phosphatase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of IRS-1 degradation by PLGγ and PP2CPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.2006

Author(s)

Journal Title

Data Source

[Journal Article] The transcription factor AP-2β causes cell enlargement and insulin resistance in 3T3-L1 adipocytes.2006

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of ATP-sensitive potassium-channel subunit Kir6.2 expression in rat intestinal insulin-production progenitor cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Regulation of ATP-sensitive potassium-channel subunit Kir6.2 expression in rat intestinal insulin-production progenitor cells.2005

Author(s)

Journal Title

Data Source

[Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Protein phosphatase 2C α as a positive regulator if insulin sensitivity through direct activation of phospphatidylinointol 3-kinase in 3T3-L1 adipocytes2004

Author(s)

Journal Title

Data Source

[Journal Article] Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes.2004

Author(s)

Journal Title

Data Source

[Journal Article] Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Protein phosphatase 2A negatively regulates insulin's metabolic signaling psthway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.2004

Author(s)

Journal Title

Data Source

[Journal Article] Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization.2004

Author(s)

Journal Title

EGAWA Katsuya 江川克哉