Okamoto Nobuto 岡本宣人

… Alternative Names

岡本宣人オカモトノブト

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Researcher Number	10346710
Affiliation (based on the past Project Information) *help	2017: 高知大学, 教育研究部医療学系臨床医学部門, 講師 2015: 高知大学, 教育研究部医療学系臨床医学部門, 講師 2013 – 2014: 高知大学, 教育研究部医療学系, 助教 2005: 高知大, 医学部, 助手 2004: 高知大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology
Keywords	Principal Investigator NASH / 消化器内科学 / 肝臓病学 / 肝線維化 / AGE-RAGE系 / 終末糖化産物 / ＮＡＳＨ / ＤＭ / DM / GLP-1 receptor … More / インクレチン / 非アルコール性脂肪肝炎 / 肝臓学 / CA-RP / CD34 / KIT / カハールの介在細胞 / 消化管間葉系腫瘍 / 炭酸脱水酵素-関連蛋白 / 炭酸脱水酵素 Less

NASH肝線維化進展および肝細胞癌発症におけるAGE-RAGE系の役割の解明Principal Investigator
- Principal Investigator
  
  岡本宣人
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kochi University
The investigation of contribution of incretin to the pathogenesis of NASHPrincipal Investigator
- Principal Investigator
  
  Okamoto Nobuto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kochi University
消化管間葉系腫瘍における炭酸脱水酵素関連蛋白の発現とその意義Principal Investigator
- Principal Investigator
  
  岡本宣人
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kochi University

All 2017 2016 2014 2013 Other

All Journal Article Presentation

[Journal Article] Differences in characteristics of glucose intolerance between patients with NAFLD and chronic hepatitis C as determined by CGMS2017
- Author(s)
  Ochi T, Kawaguchi T, Nakahara T, Ono M, Noguchi S, Koshiyama Y, Munekage K, Murakami E, Hiramatsu A, Ogasawara M, Hirose A, Mizuta H, Masuda K, Okamoto N, Suganuma N, Chayama K, Yamaguchi M, Torimura T, Saibara T
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 10146-10146
- DOI
  10.1038/s41598-017-09256-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19351, KAKENHI-PUBLICLY-16H01266, KAKENHI-PROJECT-15K09009, KAKENHI-PROJECT-15K09010, KAKENHI-PROJECT-17K09429, KAKENHI-PROJECT-15H04256
[Journal Article] High fasting insulin concentrations may be a pivotal predictor for the severity of hepatic fibrosis beyond the glycemic status in non-alcoholic fatty liver disease patients before development of diabetes mellitus．2016
- Author(s)
  Masuda K，Noguchi S，Ono M，Ochi T，Munekage K，Okamoto N，Suganuma N，Saibara T
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 10 Pages: 983-990
- DOI
  10.1111/hepr.12832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461010, KAKENHI-PROJECT-26461011, KAKENHI-PROJECT-15K09009, KAKENHI-PROJECT-15K09010, KAKENHI-PROJECT-16K19351, KAKENHI-PROJECT-17K09429
[Journal Article] PNPLA3 is involved in hepatic fatty acid and triglyceride metabolism through XBP1 and modulation of endoplasmic reticulum stress in mice.2016
- Author(s)
  Ochi T, Munekage K, Ono M, Higuchi T, Tsuda M, Hayashi Y, Okamoto N, Toda K, Sakamoto S, Oben JA, Saibara T
- Journal Title
  
  Hepatol Res
  
  Volume: 印刷中 Issue: 6 Pages: 584-592
- DOI
  10.1111/hepr.12587
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09009, KAKENHI-PROJECT-15K09010, KAKENHI-PROJECT-26461010, KAKENHI-PROJECT-26461011, KAKENHI-PROJECT-25460315, KAKENHI-PROJECT-25460371, KAKENHI-PROJECT-25460999, KAKENHI-PROJECT-16K19351
[Journal Article] Clinical effects of　fenofibrate on serum uric acids，triglyceride，and creatinine in patients with hypertriglyceridemia．2014
- Author(s)
  Oe K，Ono M，Ochi　T，Munekage K，Mizuta H，Masuda K，Okamoto N，Saibara T
- Journal Title
  
  Int Med J
  
  Volume: 21 Pages: 363-366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460999
[Journal Article] Functional role of estrogen for regulation of serum uric acid levels in pre-monopause patients with breast cancer2014
- Author(s)
  Yoshioka R，Ono M，Oe K，Ochi T，Munekage K，Masuda K，Mizuta H，Okamoto N，Saibara T
- Journal Title
  
  Int Med J
  
  Volume: 21 Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460999
[Journal Article] Glycemic variability is an independent predictive factor for development of hepatic fibrosis in nonalcoholic Fatty liver disease.2013
- Author(s)
  Hashiba M,Ono M,Okamoto N,Saibara T et.al
- Journal Title
  
  PLoS One
  
  Volume: 8(11) Issue: 11 Pages: e76161-e76161
- DOI
  10.1371/journal.pone.0076161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590979, KAKENHI-PROJECT-24590981, KAKENHI-PROJECT-25460999, KAKENHI-PROJECT-25670369
[Journal Article] Bofutsushosan，a Japanese herbal（Kampo）medicine，attenuates progression of nonalcoholic steatohepatitis in mice．2013
- Author(s)
  Ono M,Okamoto N,Saibara T et.al
- Journal Title
  
  J Gastroenterol
  
  Volume: E-pub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460999
[Journal Article] Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice2013
- Author(s)
  Masafumi Ono, Mitsunari Ogasawara, Akira Hirose, Sachiko Mogami, Nobuhiro Ootake, Kosuke Aritake, Takuma Higuchi, Nobuto Okamoto, Shuji Sakamoto, Masahiro Yamamoto, Yoshihiro Urade, Toshiji Saibara, Jude A. Oben.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 49(6) Issue: 6 Pages: 1065-1173
- DOI
  10.1007/s00535-013-0852-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J10660, KAKENHI-PROJECT-24590981, KAKENHI-PROJECT-25460371, KAKENHI-PROJECT-25460999, KAKENHI-PROJECT-26461010, KAKENHI-PROJECT-26461011
[Presentation] Involvement of PNPLA3 function for hepatic lipids metabolism through XBP1 and modulation of endoplasmic reticulum stress in mice.2017
- Author(s)
  Nagano S，Ono M，Ochi T，Munekage K，Yano Y，Mizuta H，Ogasawara M，Hirose A，Nozalki Y，Okamoto N，Iwasaki S，Jude A ObenT，Saibara T
- Organizer
  APDW 2017
- Place of Presentation
  Hong Kong Convention and Exhibition Center（香港）
- Year and Date
  2017-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09429
[Presentation] Vonoprazan-based third-line triple therapy in Helicobacter pyloli eradication and study of the diversity of antimicrobial susceptibilities.2017
- Author(s)
  Yano Y，Mizuta H，Ono M，Nagano S，Tsuda H，Kitagawa T，Hashiba M，Okamoto N，Kira M，Takeuchi H，Matsumura Y，Saibara T
- Organizer
  APDW 2017.
- Place of Presentation
  Hong Kong Convention and Exhibition Center（香港）
- Year and Date
  2017-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09429
[Presentation] Glycemic variability is an independent predictive factor for development of hepatic fibrosis in nonalcoholic fatty liver disease．2013
- Author(s)
  Ochi T,Ono M,Okamoto N,Saibara T et.al
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases 2013
- Place of Presentation
  Walter E. Washington convention center (Washington USA)
- Data Source
  KAKENHI-PROJECT-25460999
[Presentation] 24時間血糖測定から見たNAFLDとC型慢性肝炎患者の耐糖能異常の特徴
- Author(s)
  越智経浩，小野正文，川口巧，羽柴基，宗景玄祐，岡本宣人，西原利治
- Organizer
  第1回肝臓と糖尿病・代謝研究会
- Place of Presentation
  伊藤国際学術研究センター　伊藤謝恩ホール（東京）
- Year and Date
  2014-07-03 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-25460999

1. SAIBARA Toshiji (60145125)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. ONO Masafumi (70304681)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. OCHI Tsunehiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okamoto Nobuto 岡本 宣人

岡本 宣人 オカモト ノブト

Research Projects

Research Products

Co-Researchers

NASH肝線維化進展および肝細胞癌発症におけるAGE-RAGE系の役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation of contribution of incretin to the pathogenesis of NASHPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

消化管間葉系腫瘍における炭酸脱水酵素関連蛋白の発現とその意義Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differences in characteristics of glucose intolerance between patients with NAFLD and chronic hepatitis C as determined by CGMS2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High fasting insulin concentrations may be a pivotal predictor for the severity of hepatic fibrosis beyond the glycemic status in non-alcoholic fatty liver disease patients before development of diabetes mellitus．2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PNPLA3 is involved in hepatic fatty acid and triglyceride metabolism through XBP1 and modulation of endoplasmic reticulum stress in mice.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical effects of fenofibrate on serum uric acids，triglyceride，and creatinine in patients with hypertriglyceridemia．2014

Author(s)

Journal Title

Data Source

[Journal Article] Functional role of estrogen for regulation of serum uric acid levels in pre-monopause patients with breast cancer2014

Author(s)

Journal Title

Data Source

[Journal Article] Glycemic variability is an independent predictive factor for development of hepatic fibrosis in nonalcoholic Fatty liver disease.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bofutsushosan，a Japanese herbal（Kampo）medicine，attenuates progression of nonalcoholic steatohepatitis in mice．2013

Author(s)

Journal Title

Data Source

[Journal Article] Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Involvement of PNPLA3 function for hepatic lipids metabolism through XBP1 and modulation of endoplasmic reticulum stress in mice.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Vonoprazan-based third-line triple therapy in Helicobacter pyloli eradication and study of the diversity of antimicrobial susceptibilities.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Glycemic variability is an independent predictive factor for development of hepatic fibrosis in nonalcoholic fatty liver disease．2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 24時間血糖測定から見たNAFLDとC型慢性肝炎患者の耐糖能異常の特徴

Author(s)

Organizer

Okamoto Nobuto 岡本宣人

岡本宣人オカモトノブト

[Journal Article] Clinical effects of　fenofibrate on serum uric acids，triglyceride，and creatinine in patients with hypertriglyceridemia．2014