KANEKO Hiroki 金子寛生

Researcher Number	10349946
Affiliation (based on the past Project Information) *help	2017 – 2019: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所細胞核輸送ダイナミクスプロジェクト, 客員研究員 2016: 日本大学, 文理学部, 上席研究員 2015 – 2016: 日本大学, 文理学部, 研究員 2014: 日本大学, 文理学部, 教授
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Life / Health / Medical informatics
Keywords	Principal Investigator バイオインフォマティックス / 分子発症メカニズム / 遺伝性難聴 / 構造生物学 / 耳科学 / 核輸送制御 / NLS / 計算構造生物学 / エピジェネティクス / 転写因子 … More / インポーチン / 発現制御 / 生体生命情報学 / 核輸送 Less

structural biology-based translational research in diseases with a focus on hereditary hearing lossPrincipal Investigator
- Principal Investigator
  
  Kaneko Hiroki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Control of transcription factors and epigenetic factors via nuclear transport and its application to targeted therapyPrincipal Investigator
- Principal Investigator
  
  KANEKO Hiroki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  Nihon University

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Co-immunoprecipitation Methods for Detection of G Protein-Coupled Receptors in Brain Tissue2019
- Author(s)
  Kazunori Namba and Hiroki Kaneko
- Journal Title
  
  In: Odagaki Y., Borroto-Escuela D. (eds) Co-Immunoprecipitation Methods for Brain Tissue. Neuromethods
  
  Volume: 144 Pages: 1-8
- DOI
  10.1007/978-1-4939-8985-0_1
- ISBN
  9781493989843, 9781493989850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11350
[Journal Article] Homozygous EDNRB Mutation in a Patient with Waardenburg Syndrome Type 12018
- Author(s)
  Noriko Morimoto, Hideki Mutai, Kazunori Namba, Hiroki Kaneko, Rika Kosaki, Tatsuo Matsunaga
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 45 Issue: 2 Pages: 222-226
- DOI
  10.1016/j.anl.2017.03.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11350
[Journal Article] Structural and mechanistic insights into nuclear transport and delivery of the critical pluripotency factor Oct4 to DNA2017
- Author(s)
  Takahide Okuyama, Ryosuke Yamagishi, Jiro Shimada, Masaaki Ikeda, Yayoi Maruoka, Hiroki Kaneko
- Journal Title
  
  Journal of Biomolecular Structure and Dynamics
  
  Volume: 印刷中 Issue: 3 Pages: 767-778
- DOI
  10.1080/07391102.2017.1289124
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26280108, KAKENHI-PROJECT-17K11350
[Journal Article] Homozygous EDNRB Mutation in a Patient with Waardenburg Syndrome Type 12017
- Author(s)
  Noriko Morimoto, Hideki Mutai, Kazunori Namba, Hiroki Kaneko, Rika Kosaki, Tatsuo Matsunaga
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26280108
[Journal Article] Data from comprehensive analysis of nuclear localization signals2016
- Author(s)
  Ryosuke Yamagishi, Hiroki Kaneko
- Journal Title
  
  Data in Brief
  
  Volume: 6 Pages: 200-203
- DOI
  10.1016/j.dib.2015.11.064
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26280108
[Journal Article] Molecular impairment mechanisms of novel OPA1 mutations predicted by molecular modeling in patients with autosomal dominant optic atrophy and auditory neuropathy spectrum disorder2016
- Author(s)
  Kazunori Namba, Hideki Mutai, Yoichiro Takiguchi, Hirotaka Yagi, Takahide Okuyama, Shuntaro Oba, Ryosuke Yamagishi, Hiroki Kaneko, Tomoko Shintani, Kimitaka Kaga, Tatsuo Matsunaga
- Journal Title
  
  Otology & Neurotology
  
  Volume: 37 Issue: 4 Pages: 394-402
- DOI
  10.1097/mao.0000000000000978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26280108
[Journal Article] Comprehensive analysis of the dynamic structure of nuclear localization signals2015
- Author(s)
  Ryosuke Yamagishi, Takahide Okuyama, Shuntaro Oba, Jiro Shimada, Shigeru Chaen, Hiroki Kaneko
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 4 Pages: 392-396
- DOI
  10.1016/j.bbrep.2015.11.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26280108
[Journal Article] A mutation in the heparin-binding site of noggin as a novel mechanism of proximal symphalangism and conductive hearing loss2014
- Author(s)
  Masuda S., Namba K., Mutai H., Usui S., Miyanaga Y., Kaneko H., Matsunaga T.
- Journal Title
  
  Biochem Biophys Res Comm
  
  Volume: 447 Issue: 3 Pages: 196-502
- DOI
  10.1016/j.bbrc.2014.04.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592573, KAKENHI-PROJECT-26280108
[Presentation] 核移行シグナルNLSの動的構造に関する網羅的解析: NLSの天然変性領域としての可能性2016
- Author(s)
  山岸良介 ,金子寛生
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26280108
[Presentation] がん細胞におけるEZH2の細胞内局在制御機構の解明2015
- Author(s)
  趙娟、畑中彬良、勝島啓佑、大岡史治、出口彰一、市村典久、金子寛生、新城恵子、近藤豊
- Organizer
  第9回日本エピジェネティクス研究会年会
- Place of Presentation
  一橋講堂
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26280108
[Presentation] 核輸送タンパク質と相互作用することにより核輸送を制御する分子の探索2014
- Author(s)
  山岸良介 , 奥山隆英 , 島田次郎 , 大庭俊太朗 , 茶圓茂 , 安原徳子 , 米田悦啓 , 金子寛生
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26280108
[Presentation] 核輸送による遺伝子発現制御と細胞運命決定のメカニズム2014
- Author(s)
  安原徳子、山岸良介、金子寛生、米田悦啓
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-26280108
[Presentation] 転写因子と核内輸送因子の複合体構造の予測2014
- Author(s)
  奥山隆英、山岸良介、島田次郎、安原徳子、米田悦啓、金子寛生
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26280108

1. YONEDA Yoshihiro (80191667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. YASUHARA Noriko (90423152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KONDOU Yutaka (00419897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. OKUZAKI Daisuke (00346131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMAGISHI Ryosuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. SHIMADA Jiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. MUTAI Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 宮冬樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KANEKO Hiroki 金子 寛生

Research Projects

Research Products

Co-Researchers

structural biology-based translational research in diseases with a focus on hereditary hearing lossPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Control of transcription factors and epigenetic factors via nuclear transport and its application to targeted therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Co-immunoprecipitation Methods for Detection of G Protein-Coupled Receptors in Brain Tissue2019

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Homozygous EDNRB Mutation in a Patient with Waardenburg Syndrome Type 12018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural and mechanistic insights into nuclear transport and delivery of the critical pluripotency factor Oct4 to DNA2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Homozygous EDNRB Mutation in a Patient with Waardenburg Syndrome Type 12017

Author(s)

Journal Title

Data Source

[Journal Article] Data from comprehensive analysis of nuclear localization signals2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular impairment mechanisms of novel OPA1 mutations predicted by molecular modeling in patients with autosomal dominant optic atrophy and auditory neuropathy spectrum disorder2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive analysis of the dynamic structure of nuclear localization signals2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A mutation in the heparin-binding site of noggin as a novel mechanism of proximal symphalangism and conductive hearing loss2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 核移行シグナルNLSの動的構造に関する網羅的解析: NLSの天然変性領域としての可能性2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] がん細胞におけるEZH2の細胞内局在制御機構の解明2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 核輸送タンパク質と相互作用することにより核輸送を制御する分子の探索2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 核輸送による遺伝子発現制御と細胞運命決定のメカニズム2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KANEKO Hiroki 金子寛生