Into Takeshi 引頭毅

… Alternative Names

引頭毅イントウタケシ

INTO Takeshi 引頭毅

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Researcher Number	10360918
Other IDs	https://orcid.org/0000-0001-9411-9480
External Links
Affiliation (Current)	2025: 朝日大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2025: 朝日大学, 歯学部, 教授 2022 – 2023: 朝日大学, 歯学部, 教授 2018 – 2020: 朝日大学, 歯学部, 教授 2015 – 2016: 朝日大学, 歯学部, 准教授 2011 – 2014: 朝日大学, 歯学部, 講師 … More 2009: 国立長寿医療センター研究所, 口腔疾患研究部, 室長 2009: 朝日大学, 歯学部, 助教 2008: 国立長寿医療センター 2007: National Institute for Longevity Sciences,NCGG, 口腔疾患研究部, 室長 2006: 国立長寿医療センター, (研究所)・口腔疾患研究部, 室長 2005: 北大, 歯学研究科(研究院), 助手 2004: 北海道大学, 大学院・歯学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related / Basic Section 57080:Social dentistry-related / Pathobiological dentistry/Dental radiology / Biological Sciences Except Principal Investigator Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related / Orthodontic/Pediatric dentistry / Pathobiological dentistry/Dental radiology / Periodontal dentistry
Keywords	Principal Investigator 自然免疫 / MyD88 / シェーグレン症候群 / 唾液腺 / 一酸化窒素 / 歯周病 / 唾液 / ホスファチジルセリン結合性タンパク質 / アミロイド / ホスファチジルセリン結合タンパク質 … More / マトリックス / バイオフィルム / 歯垢 / 疾患モデルマウス / 樹状細胞 / TLR9 / 細胞内シグナル伝達 / 三次リンパ組織 / リンパ球浸潤 / 自己免疫性唾液腺炎 / エンドサイトーシス / 小胞輸送 / 口腔免疫 / 抗菌因子 / インターセクチン / TACI / B細胞 / 粘膜免疫 / ＴＡＣＩ / Toll様受容体 / ＭｙＤ８８ / ＩｇＡ / Ｂ細胞 / IgA / 自己免疫 / S-ニトロシル化 / myD88 / TLR / Trx / シグナル伝達 / exocytosis / Weibel-Palade body / gingipain / P.gingivalis / チオレドキシン / caspase / AP-1 / NF-κB / p38 MAPK / ASK1 / Toll-like receptor (TLR) 2 … More Except Principal Investigator 歯周病 / 免疫・感染・炎症 / 炎症性腸疾患 / GBPs / インフラマソーム / LPS / 歯周病原細菌 / 上皮ー間葉分化転換 / 口蓋突起内側縁上皮細胞 / ゲフィチニブ / EGFR阻害剤 / 口蓋裂軽症化作用 / 上皮成長因子受容体 / TGFβ3 / TGFβ3 ノックアウトマウス / DNAメチル化酵素阻害剤 / 上皮成長因子阻害剤 / 口蓋裂表現型 / シグナル伝達系 / エピジェネティクス / 分子標的治療薬 / TGFβ3ノックアウトマウス / 口蓋裂 / O-GlcNAc / リン酸化蛋白質 / 糖蛋白質 / OmpA様蛋白質 / OmpA / リン酸化修飾 / 糖鎖修飾 / 翻訳後修飾 / 蛋白質 / 歯周病関連細菌 / シグナリングカスケード / 歯根膜線維芽細胞 / 炎症性シグナリングカスケード / 歯根膜細胞 / 細胞内シグナル伝達機構 / ヒト歯根膜細胞線維芽細胞 / メカニカルストレス / 加齢 / 活性酸素 / 血液凝固 / 細胞情報伝達機構 / 医薬分子設計 / 膜輸送 / 歯周免疾機能学 / 炎症性サイトカイン / 開口放出 / 高血圧 / サイトカイン Less

歯垢マトリックスの未解明領域の探求と新たな歯垢制御戦略Principal Investigator
- Principal Investigator
  
  引頭毅
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Asahi University
Analysis of the role of phosphatidylserine-binding proteins accumulated in dental plaque and their relevance to the onset of periodontitisPrincipal Investigator
- Principal Investigator
  
  引頭毅
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Asahi University
GBPsによるLPS認識が歯周炎ならびに炎症性腸疾患に及ぼす病因的役割の解明
- Principal Investigator
  
  片岡嗣雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Asahi University
The commander of autoimmune sialadenitis: regulatory mechanisms of tertiary lymphoid tissue formation by MyD88-dependent signalingPrincipal Investigator
- Principal Investigator
  
  Into Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Asahi University
Study on the regulatory mechanisms of production of antimicrobial factors in salivary grands by the vesicular transport protein intersectinPrincipal Investigator
- Principal Investigator
  
  Into Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Elucidation of the mechanism to improve the cleft palate phenotype with the molecular target drug
- Principal Investigator
  
  TAKIGAWA Toshiya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Regulatory effect of the TLR/TACI-MyD88 signaling pathway on immune responses associated with the homing of IgA-producing B cells into salivary glandsPrincipal Investigator
- Principal Investigator
  
  INTO Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Asahi University
Post-translational modifications of proteins from periodontpathic bacteria: role of glycosylation and phosphorylation
- Principal Investigator
  
  MURAKAMI Yukitaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Investigation of stretch-induced intracellular signal transduction in human periodontal ligament fibroblasts exposed to periodontopathic factors.
- Principal Investigator
  
  YAGI Takakazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kagoshima University
  Asahi University
口腔自然免疫機構における多量体型免疫グロブリン受容体pIgRの役割の解明Principal Investigator
- Principal Investigator
  
  引頭毅
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  National Institute for Longevity Sciences,NCGG
一酸化窒素による細菌感染時応答の時間的・空間的制御機構の解明Principal Investigator
- Principal Investigator
  
  引頭毅
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences,NCGG
Development of new therapy for periodontal disease based on regulating exocytosis
- Principal Investigator
  
  MATSUSHITA Kenji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  National Institute for Longevity Sciences,NCGG
  国立長寿医療センター研究所
歯肉上皮機能の分子機構の解明とその制御に関する研究
- Principal Investigator
  
  松下健二
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute for Longevity Sciences,NCGG
歯周病発症におけるチオレドキシンの役割と作用メカニズムPrincipal Investigator
- Principal Investigator
  
  引頭毅
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  National Institute for Longevity Sciences,NCGG
口腔微生物由来分子パターンによって誘導される細胞の生死のメカニズムPrincipal Investigator
- Principal Investigator
  
  引頭毅
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University

[Book] Research Advances in Biological Chemistry2007
- Author(s)
  Into T.(分著)
- Publisher
  Global Research Network(Kerala,India)
- Data Source
  KAKENHI-PROJECT-18791363
[Journal Article] Effect of NLRP3 deficiency on cytotoxic and IL-1β-producing activities of synthetic candidalysin peptide2023
- Author(s)
  Mori Taiki、Kataoka Hideo、Into Takeshi
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 65 Issue: 4 Pages: 287-292
- DOI
  10.1016/j.job.2023.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09937, KAKENHI-PROJECT-22K09951
[Journal Article] Role of LL-37 in Oral Bacterial DNA Accumulation in Dental Plaque2023
- Author(s)
  Tanabe G.、Mori T.、Araki M.、Kataoka H.、Into T.
- Journal Title
  
  Journal of Dental Research
  
  Volume: 103 Issue: 2 Pages: 177-186
- DOI
  10.1177/00220345231210767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09937, KAKENHI-PROJECT-22K09951
[Journal Article] Solubility affects IL-1β-producing activity of the synthetic candidalysin peptide2022
- Author(s)
  Mori Taiki、Kataoka Hideo、Tanabe Gen、Into Takeshi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 8 Pages: e0273663-e0273663
- DOI
  10.1371/journal.pone.0273663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09937
[Journal Article] Citrobacter koseri stimulates dendritic cells to induce IL-33 expression via abundant ATP production2021
- Author(s)
  Kataoka H., Mori T., and Into T.
- Journal Title
  
  Journal of Medical Microbiology
  
  Volume: 70(3) Issue: 3
- DOI
  10.1099/jmm.0.001303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09561, KAKENHI-PROJECT-19K10096
[Journal Article] Effect of Myd88 deficiency on gene expression profiling in salivary glands of female non-obese diabetic (NOD) mice2021
- Author(s)
  Mori T., Kataoka H., and Into T.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09561
[Journal Article] Naringenin suppresses Toll-like receptor 2-mediated inflammatory responses through inhibition of receptor clustering on lipid rafts2020
- Author(s)
  Hideo Kataoka, Ayumi Saeki, Akira Hasebe, Ken-Ichiro Shibata, Takeshi Into
- Journal Title
  
  Food Sci Nutr .
  
  Volume: 9 Issue: 2 Pages: 963-972
- DOI
  10.1002/fsn3.2063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10096, KAKENHI-PROJECT-18K09561
[Journal Article] Effect of the Antimicrobial Peptide LL-37 on Gene Expression of Chemokines and 29 Toll-like Receptor-Associated Proteins in Human Gingival Fibroblasts Under Stimulation With Porphyromonas Gingivalis Lipopolysaccharide2020
- Author(s)
  Megumi Inomata, Toshi Horie, Takeshi Into
- Journal Title
  
  Probiotics Antimicrob Proteins
  
  Volume: 12 Issue: 1 Pages: 64-72
- DOI
  10.1007/s12602-019-09600-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09561, KAKENHI-PROJECT-17K17114, KAKENHI-PROJECT-18K09544
[Journal Article] OmpA-like proteins of Porphyromonas gingivalis contribute to serum resistance and prevent Toll-like receptor 4-mediated host cell activation2018
- Author(s)
  Inomata M, Horie T, Into T
- Journal Title
  
  PLoS One
  
  Volume: 13(8) Issue: 8 Pages: e0202791-e0202791
- DOI
  10.1371/journal.pone.0202791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09561, KAKENHI-PROJECT-15K11094, KAKENHI-PROJECT-16K11464
[Journal Article] OmpA-Like Proteins of Porphyromonas gingivalis Mediate Resistance to the Antimicrobial Peptide LL-372018
- Author(s)
  Horie T, Inomata M, Into T
- Journal Title
  
  Journal of Pathogens
  
  Volume: 2018 Pages: 2068435-2068435
- DOI
  10.1155/2018/2068435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09561, KAKENHI-PROJECT-15K11094, KAKENHI-PROJECT-16K11464
[Journal Article] MyD88 signaling causes autoimmune sialadenitis through formation of high endothelial venules and upregulation of LTβ receptor-mediated signaling2018
- Author(s)
  Into T, Niida S, Shibata KI
- Journal Title
  
  Scientific Reports
  
  Volume: 8(1) Issue: 1 Pages: 14272-14272
- DOI
  10.1038/s41598-018-32690-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09561
[Journal Article] Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD882017
- Author(s)
  Into T., Horie T., Inomata M., Gohda J., Inoue J., Murakami Y., and Niida S.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1009-1009
- DOI
  10.1038/s41598-017-01246-w
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462803, KAKENHI-PROJECT-15K11094, KAKENHI-PLANNED-16H06575
[Journal Article] 粘膜を防御する抗体クラスとその産生誘導機構2014
- Author(s)
  引頭毅
- Journal Title
  
  岐阜歯科学会雑誌
  
  Volume: 40(3) Pages: 209-228
- NAID
  120005867899
- Data Source
  KAKENHI-PROJECT-23390431
[Journal Article] MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands2014
- Author(s)
  Takeshi Into, Toshiya Takigawa, Shumpei Niida, Ken-ichiro Shibata
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 11 Pages: e113333-e113333
- DOI
  10.1371/journal.pone.0113333
- NAID
  120005540298
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462803
[Journal Article] Atg5 regulates formation of MyD88 condensed structures and MyD88-dependent signal transduction Biochem2013
- Author(s)
  Inomata M., Into T., Niida S., and Murakami Y
- Journal Title
  
  Biophys. Res. Commun
  
  Volume: 37(4) Pages: 509-514
- Data Source
  KAKENHI-PROJECT-23390431
[Journal Article] Atg5 regulates formation of MyD88 condensed structures and MyD88-dependent signal transduction.2013
- Author(s)
  Inomata M., Into T., Niida S., and Murakami Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 37(4) Issue: 4 Pages: 509-514
- DOI
  10.1016/j.bbrc.2013.06.094
- NAID
  120005541902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390431
[Journal Article] Autophagy in regulation of Toll-like receptor signaling2012
- Author(s)
  Into T., Inomata M., Takayama E., and Takigawa T
- Journal Title
  
  Cell. Signal
  
  Volume: 24(6) Pages: 1150-1162
- Data Source
  KAKENHI-PROJECT-23390431
[Journal Article] Autophagy in regulation of Toll-like receptor signalling2012
- Author(s)
  Into T., Inomata M., Takayama E., Takigawa T.
- Journal Title
  
  Cellular Signalling
  
  Volume: 24 Issue: 6 Pages: 1150-1162
- DOI
  10.1016/j.cellsig.2012.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390431, KAKENHI-PROJECT-23792158, KAKENHI-PROJECT-24592851
[Journal Article] Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A202012
- Author(s)
  Inomata M., Niida S., Shibata K., and Into T
- Journal Title
  
  Cell. Mol. Life Sci
  
  Volume: 69(6) Pages: 963-979
- Data Source
  KAKENHI-PROJECT-23390431
[Journal Article] Nuclear dot protein 52, an autophagy-associated protein, regulates Toll-like receptor signaling2012
- Author(s)
  Inomata M., and Into T.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 54 Issue: 3 Pages: 151-154
- DOI
  10.1016/j.job.2012.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390431, KAKENHI-PROJECT-23792158
[Journal Article] Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A202012
- Author(s)
  Inomata, M., Niida, S., Shibata, K., Into, T
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 69 Issue: 6 Pages: 963-979
- DOI
  10.1007/s00018-011-0819-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352, KAKENHI-PROJECT-23390431, KAKENHI-PROJECT-23792158
[Journal Article] Nuclear dot protein 52, an autophagy-associated protein, regulates Toll-like receptor signaling2012
- Author(s)
  Inomata M., and Into T
- Journal Title
  
  J. Oral Biosci
  
  Volume: 54(3) Pages: 151-154
- Data Source
  KAKENHI-PROJECT-23390431
[Journal Article] IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6-and SOCS-1-dependent mechanisms2009
- Author(s)
  Inomata M, Into T, Nakashima M, Noguchi T, Matsushita K
- Journal Title
  
  Molecular Immunology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Regeneration of dental pulp after pulpotomy by transplantation of CD31(-)/CD146(-) side population cells from a canine tooth2009
- Author(s)
  Iohara K, Zheng L, Ito M, Ishizaka R, Nakamura H, Into T, Matsushita K, Nakashima M
- Journal Title
  
  Regen Med 4
  
  Pages: 377-385
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Matrix Metalloproteinase-3 Accelerates Wound Healing Following Dental Pulp Injury2009
- Author(s)
  Zheng L, Amano K, Iohara K, Ito M, Imabayashi K, Into T, Matsushita K, Nakamura H, Nakashima M
- Journal Title
  
  Am J Pathol 175
  
  Pages: 1905-1914
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6-and SOCS-1-dependent mechanisms.2009
- Author(s)
  Inomata M, Into T, Nakashima M, Noguchi T, Matsushita K
- Journal Title
  
  Mol Immunol 46
  
  Pages: 2080-2089
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6-and SOCS-I-dependent mechanisms2009
- Author(s)
  Inomata M, Into T, Nakashima M, Noguchi T, Matsushita K
- Journal Title
  
  Molecular Immunology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659494
[Journal Article] Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses.2008
- Author(s)
  Into T, Inomata M, Nakashima M, Shibata K, Hacker H, Matsushita K.
- Journal Title
  
  Mol Cell Biol 28
  
  Pages: 1338-1347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659494
[Journal Article] Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses.2008
- Author(s)
  Into T, Inomata M, Nakashima M, Shibata K, Hacker H, Matsushita K.
- Journal Title
  
  Mol Cell Biol 28
  
  Pages: 1338-1347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Nitric oxide regulates vascular calcification by interfering with TGF-signalling.2008
- Author(s)
  Kanno Y, Into T, Lowenstein CJ, Matsushita K.
- Journal Title
  
  Cardiovasc Res. 77
  
  Pages: 221-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Nitric oxide regulates vascular calcification by interfering with TGF-signalling.2008
- Author(s)
  Kanno Y, Into T, Lowenstein CJ, Matsushita K.
- Journal Title
  
  Cardiovasc Res. 77
  
  Pages: 221-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659494
[Journal Article] Nitric oxide regulates vascular calcification by interfering with TGF-signaling2008
- Author(s)
  Kanno Y, Into T, Lowenstein CJ, Matsushita K
- Journal Title
  
  Cardiovasc Res 77
  
  Pages: 221-730
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses2008
- Author(s)
  Into T, Inomata M, Nakashima M, Shibata K, Hacker H, Matsushita K
- Journal Title
  
  Mol Cell Biol 28
  
  Pages: 1338-1347
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] A Novel Stem Cell Source for Vasculogenesis in Ischemia: Subfraction of Side Population Cells from Dental Pulp2008
- Author(s)
  Iohara K, Zheng L, Wake H, Ito M, Nabekura J, Wakita H, Nakamura H, Into T, Matsushita K, Nakashima M
- Journal Title
  
  Stem Cells 26
  
  Pages: 2408-2418
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Regulation of MyD88-dependent Signaling Events By S-nitrosylation retards Toll-like receptor signal transduction and initiation of acute-phase immune responses2008
- Author(s)
  Into T., Inomata M., Nakashima M., Shiata K., Hacker H., and Matsushita K.
- Journal Title
  
  Mol. Cell. Biol 28
  
  Pages: 1338-1347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041079
[Journal Article] Regulation of MyD88-dependent signaling events by S-nitrosylation retards Toll-like recepror signal transduction and initiation of acute-phase immune responses2008
- Author(s)
  Into T. Inomata M., Nakashima M., Shibata K., Hacker H., and Matsushita K.
- Journal Title
  
  Mol.Cell.Biol. 28
  
  Pages: 1338-1347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791363
[Journal Article] Runx3 negatively regulates Osterix expression in dental pulp cells2007
- Author(s)
  Zheng L, Iohara K, Ishikawa M, Into T, Takano-Yamamoto T, Matsushita K, Nakashima M
- Journal Title
  
  Biochem J 405
  
  Pages: 69-75
- NAID
  10020162665
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells.2007
- Author(s)
  Into T., Kanno Y., Dohkan J., Nakashima M., Inomata M., Shibata K., Lowenstein C.J., Matsushita K.
- Journal Title
  
  Journal of Biological Chemistry 282(11)
  
  Pages: 8134-8141
- Data Source
  KAKENHI-PROJECT-18791363
[Journal Article] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors.2007
- Author(s)
  Inomata M, Into T, Ishihara Y, Nakashima M, Noguchi T, Matsushita K.
- Journal Title
  
  Microbes Infect. 9
  
  Pages: 1500-1506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659494
[Journal Article] Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells2007
- Author(s)
  Into T, Kanno Y, Dohkan JI, Nakashima M, Inomata M, Shibata KI, Lowenstein CJ, Matsushita K
- Journal Title
  
  J Biol Chem 282
  
  Pages: 8134-8141
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells.2007
- Author(s)
  Into T, Kanno Y, Dohkan J, Nakashima M, Inomata M, Shibata K, Lowenstein CJ, Matsushita K.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 8134-8141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659494
[Journal Article] Synthesis and characterization of a dipalmitoylated lipopeptide derived from paralogous lipoproteins of Mycoplasma pneumoniae.2007
- Author(s)
  Into T, Dohkan J, Inomata M, Nakashima M, Shibata K, Matsushita K.
- Journal Title
  
  Infect Immun 75
  
  Pages: 2253-2259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells.2007
- Author(s)
  Into T, Kanno Y, Dohkan J, Nakashima M, Inomata M, Shibata K, Lowenstein CJ, Matsushita K.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 8134-8141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Synthesis and characterization of a dipalmitoylated lipopeptide derived from paralogous lipoproteins of Mycoplasma pneumoniae2007
- Author(s)
  Into T, Dohkan J, Inomata M, Nakashima M, Shibata K, Matsushita K
- Journal Title
  
  Infect Immun 27
  
  Pages: 2253-2259
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vasc ular endothelial cells through protease-activated receptors.2007
- Author(s)
  Inomata M, Into T, Ishihara Y, Nakashima M, Noguchi T, Matsushita K.
- Journal Title
  
  Microbes Infect. 9
  
  Pages: 1500-1506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors2007
- Author(s)
  Inomata M, Into T, Ishihara Y, Nakashima M, Noguchi T, Matsushita K
- Journal Title
  
  Microbes Infect 9
  
  Pages: 1500-1506
- Data Source
  KAKENHI-PROJECT-19390538
[Journal Article] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endot helial cells through protease-activateed receptors2007
- Author(s)
  Inomata M., Into T., IshiharaY., Nakashima M., Noguchi T., and Matsushita K
- Journal Title
  
  Microbes Infect 9
  
  Pages: 1500-1506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791363
[Journal Article] Synthesis and characterization of a dipalmitoylated lipopeptide derived from paralogous lipoproteins of Mycoplasma pneumoniae.2007
- Author(s)
  Into T, Dohkan J, Inomata M, Nakashima M, Shibata K, Matsushita K.
- Journal Title
  
  Infect Immun 75
  
  Pages: 2253-2259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659494
[Journal Article] Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells2007
- Author(s)
  Into T., Kanno Y., Dohkan J., Nakashima M, Inomata M., Shibata K., Lowenstein C.J., and Matsushita K.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 8134-8141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791363
[Journal Article] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endot helial cells through protease-activated receptors2007
- Author(s)
  Inomata M., Into T., Ishihara Y., Nakashima M., Noguchi T., and Matsushita K.
- Journal Title
  
  Microbes Infect 9
  
  Pages: 1500-1506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041079
[Journal Article] Arginine-specific gingipains from Porphyromonas gingivalis deprive protective functions of secretory leukocyte protease inhibitor in periodontal tissue.2006
- Author(s)
  Into T., Inomata, M., Kanno Y., Matsuyama T., Machigashira M., Izumi Y., Imamura T., Nakashima M., Noguchi T., Matsushita K.
- Journal Title
  
  Clinical and Experimental Immunology 145(3)
  
  Pages: 545-554
- Data Source
  KAKENHI-PROJECT-18791363
[Presentation] カンジダリシンの生理活性におけるNLRP3インフラマソーム経路の関与について．2023
- Author(s)
  森大気, 片岡嗣雄, 田邊元, 引頭毅
- Organizer
  第65回歯科基礎医学会学術大会ならびに総会
- Data Source
  KAKENHI-PROJECT-22K09951
[Presentation] 抗菌ペプチド LL-37は歯垢中に口腔内細菌DNAを堆積させる2023
- Author(s)
  Tanabe G., Mori T., Araki M., Kataoka H., Into T.
- Organizer
  第65回歯科基礎医学会学術大会（東京）
- Data Source
  KAKENHI-PROJECT-22K09937
[Presentation] 抗菌ペプチドLL-37は歯垢中に口腔内細菌DNAを堆積させる.2023
- Author(s)
  田邊元，森大気, 荒木美穂, 片岡嗣雄, 引頭毅
- Organizer
  第65回歯科基礎医学会学術大会ならびに総会
- Data Source
  KAKENHI-PROJECT-22K09951
[Presentation] カンジダリシンの生理活性におけるNLRP3インフラマソーム経路の関与について2023
- Author(s)
  Mori T., Kataoka H., Tanabe G., Into T.
- Organizer
  第65回歯科基礎医学会学術大会（東京）
- Data Source
  KAKENHI-PROJECT-22K09937
[Presentation] Antimicrobial peptide LL-37 binds to oral bacterial DNA to form degradation-resistant complexes2022
- Author(s)
  Tanabe G., Kataoka H., Mori T., Into T.
- Organizer
  第64回歯科基礎医学会学術大会（徳島）
- Data Source
  KAKENHI-PROJECT-22K09937
[Presentation] IL-1β-producing activity of the synthetic candidalysin peptide is affected by solubility2022
- Author(s)
  Mori T., Kataoka H., Tanabe G., Into T.
- Organizer
  第64回歯科基礎医学会学術大会（徳島）
- Data Source
  KAKENHI-PROJECT-22K09937
[Presentation] Analysis of IL-33-inducing activity of Citrobacter koseri in dendritic cells2021
- Author(s)
  Kataoka H., Mori T., Into T.
- Organizer
  第94回日本細菌学会総会（オンライン開催；岡山）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] Role of P2X7 in LL-37-induced chemokine production and cytotoxicity in gingival fibroblasts2020
- Author(s)
  Inomata M. and Into T.
- Organizer
  第93回日本細菌学会総会（名古屋）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] The roles of TLR2 in the NLRP3 inflammasome activation induced by mycoplasmal lipoproteins/lipopeptides2020
- Author(s)
  Saeki A., Into T., Hasebe A., and Shibata K.
- Organizer
  第62回歯科基礎医学会学術大会（オンライン開催；鹿児島）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] Citrobacter koseri induces IL-33 production in dendritic cells through ATP2020
- Author(s)
  Kataoka H., Mori T., Into T.
- Organizer
  第62回歯科基礎医学会学術大会（オンライン開催；鹿児島）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] A role of MyD88 signaling in lymphoid follicle formation in the salivary gland of NOD mice2020
- Author(s)
  Mori T., Kataoka H., Into T.
- Organizer
  第62回歯科基礎医学会学術大会（オンライン開催；鹿児島）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] Activation of NLRP3 inflammasome by mycoplasmal lipoproteins/lipopeptides only through the TLR2-mediated signals in murine macrophages2020
- Author(s)
  Saeki A., Into T., Hasebe A. and Shibata K.
- Organizer
  第93回日本細菌学会総会（名古屋）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] Porphyromonas gingivalisの外膜糖タンパク質は抗菌ペプチドLL-37への抵抗性を有する2019
- Author(s)
  引頭　毅、堀江　俊、猪俣　恵
- Organizer
  第92回日本細菌学会総会（札幌）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] IL-1β release by living macrophages in response to mycoplasmal lipoproteins and lipopeptides2019
- Author(s)
  Saeki A., Into T., Hasebe A., Suzuki T. and Shibata K.
- Organizer
  第61回歯科基礎医学会学術大会（東京）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] Involvement of P2X7 receptor in chemokine production and cytotoxicity induced by the antimicrobial peptide LL-37 in human gingival fibroblasts2019
- Author(s)
  Inomata M. and Into T.
- Organizer
  第61回歯科基礎医学会学術大会（東京）
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] MyD88 signaling causes formation of high endothelial venules to develop autoimmune sialadenitis2018
- Author(s)
  Into T., Inomata, M., and Abe M.
- Organizer
  The JADR 2018/ 66th Japanese Division Meeting 2018
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] MyD88依存的シグナルは高内皮細静脈の形成を介して自己免疫性唾液腺炎を誘導する2018
- Author(s)
  引頭　毅、猪俣　恵、堀江　俊、安部雅世
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] Outer membrane proteins of Porphyromonas gingivalis are involved in the resistance to antimicrobial peptides2018
- Author(s)
  Inomata, M., Abe M, and Into T.
- Organizer
  The JADR 2018/ 66th Japanese Division Meeting 2018
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] The antimicrobial peptide LL-37 exerts regulatory effects on expression of Toll-like receptor-associated genes in human gingival fibroblasts2018
- Author(s)
  Abe M, Inomata, M., and Into T.
- Organizer
  The JADR 2018/ 66th Japanese Division Meeting 2018
- Data Source
  KAKENHI-PROJECT-18K09561
[Presentation] TRAF6によって制御される基礎的オートファジーはMyD88の細胞内蓄積により誘導される炎症性シグナルの自己活性化を抑制している2016
- Author(s)
  引頭　毅、堀江　俊、猪俣　恵、村上幸孝
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26462803
[Presentation] TRAF6-regulated basal autophagy prevents MyD88 accumulation and autoactivation of proinflammatory signaling2016
- Author(s)
  Into T.
- Organizer
  The 45th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄コンベンションセンター（宜野湾）
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-26462803
[Presentation] 歯周病関連細菌Porphyromonas gingivalisのMfa1線毛における付随成分Mfa3の局在および機能に関する研究2014
- Author(s)
  村上　幸孝、長谷川　義明、猪俣　恵、引頭　毅
- Organizer
  第43回東海乳酸菌研究会研究報告会
- Place of Presentation
  中日パレス（名古屋市）
- Data Source
  KAKENHI-PROJECT-23592720
[Presentation] 歯周病関連細菌Porphyromonas gingivalisのMfa1線毛における付随成分Mfa3の局在および機能に関する研究2014
- Author(s)
  村上幸孝,長谷川義明,猪俣恵,引頭毅
- Organizer
  第43回東海乳酸菌研究会研究報告会
- Place of Presentation
  中日パレス(名古屋市)
- Year and Date
  2014-02-08
- Data Source
  KAKENHI-PROJECT-23592720
[Presentation] MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands2014
- Author(s)
  Into T., and Shibata K
- Organizer
  The 43th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  京都
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-26462803
[Presentation] 唾液腺における抗体ならびに抗菌性タンパク質産生におけるシグナル伝達分子MyD88 の役割の検討2014
- Author(s)
  引頭　毅、猪俣　恵、稲葉　裕明、村上　幸孝
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26462803
[Presentation] DNAメチル化酵素阻害剤投与によるTGFβ3ノックアウトマウス胎児の口蓋裂表現型の薬理学的改善に関する研究2014
- Author(s)
  杉山明子、滝川俊也、引頭　毅
- Organizer
  第56回歯科基礎医学会・学術大会
- Place of Presentation
  福岡市
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24592788
[Presentation] イレッサ投与によるTGFβ3ノックアウトマウス胎児の口蓋裂表現型の薬理的改善2013
- Author(s)
  滝川俊也、引頭　毅、高木秀太、今井田千恵
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-24592788
[Presentation] シグナル伝達分子MyD88は顎下腺におけるB-1細胞浸潤の制御と唾液中の抗体産生の調節に関与する2013
- Author(s)
  引頭　毅、滝川俊也、柴田健一郎
- Organizer
  歯科基礎医学会学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] 歯周病関連細菌Porphyromonas gingivalisから同定された糖蛋白質の増殖およびバイオフィルム形成への関与2013
- Author(s)
  村上幸孝,長谷川義明,引頭毅,猪俣恵
- Organizer
  第42回東海乳酸菌研究会研究報告会
- Place of Presentation
  中日パレス(名古屋市)
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-23592720
[Presentation] 歯周病関連細菌Tannerella forsythiaにおけるOmpA様タンパク質の機能に関する研究2012
- Author(s)
  村上幸孝、長谷川義明、引頭毅、猪俣恵
- Organizer
  第41回東海乳酸菌研究会研究報告会
- Place of Presentation
  中日パレス（名古屋市）
- Data Source
  KAKENHI-PROJECT-23592720
[Presentation] 歯周病関連細菌Tannerella forsythiaにおけるOmpA様タンパク質の機能に関する研究2012
- Author(s)
  村上幸孝,長谷川義明,引頭毅,猪俣恵
- Organizer
  第41回東海乳酸菌研究会研究報告会
- Place of Presentation
  中日パレス(名古屋市)
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-23592720
[Presentation] TLRシグナルを制御するオートファジー受容体2011
- Author(s)
  引頭毅
- Organizer
  日本細菌学会北海道支部学術懇談会
- Place of Presentation
  北海道大学獣医学部(札幌市北区)
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] Th2由来サイトカインはSTAT6を介して血管内皮細胞特異的な分泌顆粒の構成因子の発現量を変化させる2009
- Author(s)
  猪俣恵, 引頭毅, 石原裕一, 松下健二, 野口俊英
- Organizer
  第52回日本歯周病学会春季学術大会
- Place of Presentation
  岡山
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors2008
- Author(s)
  Inomata M, Into T, Ishihara Y, Matsushita K, Noguchi T
- Organizer
  The 94th annual meeting of the American Academy of Periodontology
- Place of Presentation
  Lake Tahoe, California, USA
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors2008
- Author(s)
  Inomata M, Into T, Ishihara Y, Matsushita K, Noguchi T
- Organizer
  The 94th annual meeting of the American Academy of Periodontology
- Place of Presentation
  Seatle, USA
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors2008
- Author(s)
  Inomata M, Into T, Ishihara Y, Matsushita K, Noguchi T
- Organizer
  The 94th annual meeting of the American Academy of Periodontology
- Place of Presentation
  Lake Tahoe, California, USA
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19659494
[Presentation] 高い血管新生能を有する歯髄CD31陰性SP細胞による歯髄再生2008
- Author(s)
  庵原耕一郎、鄭力、和気弘明、伊藤正孝、鍋倉淳一、脇田英明、中村洋、引頭毅、松下健二、中島美砂子
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-13
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Gingipainはprotease-activated receptorの活性化を介してWeibel-Palade小体のエキソサイトーシスを誘導し、血管内皮細胞の炎症応答を増強する2007
- Author(s)
  猪俣恵、引頭毅、中島美砂子、野口俊英、松下健二
- Organizer
  第50回日本歯周病学会春季学術大会
- Place of Presentation
  横須賀
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Gingipainはprotease-activated receptorの活性化を介して Weibel-Palade小体のエキソサイトーシスを誘導し、血管内皮細胞の炎症応答を増強する2007
- Author(s)
  猪俣恵、引頭毅、中島美砂子、野口俊英、松下健二
- Organizer
  第49回歯科基礎医学会総会
- Place of Presentation
  札幌
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Nitric oxide controls Toll-like receptor signal transduction through a redox-sensitive modification of MyD882007
- Author(s)
  Into T., Inomata M., Nakashima M., Shibata K., and Matsushita K.
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路市
- Year and Date
  2007-09-04
- Data Source
  KAKENHI-PROJECT-19041079
[Presentation] Nitric oxide controls Toll-like receptor signal transduction through a redox-sensitive modification of MyD82007
- Author(s)
  Into T, Inomata M, Nakashima M, Shibata K, Matsushita K
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji, Japan
- Year and Date
  2007-09-04
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] A Potential New Cell Source for Vasculogenesis in Ischemia, CD31-;CD146- Side Population Cells from Dental Pulp2007
- Author(s)
  Nakashima M, Iohara K, Zheng L, Wake H, Ito M, Wakita H, Nabekura J, Nakamura H, Into T, Matsushita K
- Organizer
  The American Society for Cell Biology 47th Annual Meeting
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2007-12-04
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Gingipainはprotease-activated receptorの活性化を介してWeibel-Palade小体のエキソサイトーシスを誘導し、血管内皮細胞の炎症応答を増強する2007
- Author(s)
  猪俣恵、引頭毅、中島美砂子、野口俊英、松下健二
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] Nitric oxide controls Toll-like receptor signal transduction through a red-ox-sensitive modification of MyD882007
- Author(s)
  Into T., Inomata M., Nakashima M., Shibata K., and Matsushita K.
- Organizer
  The 7th AwajiInternational Forum on Infection and Immunity
- Place of Presentation
  淡路市
- Year and Date
  2007-09-04
- Data Source
  KAKENHI-PROJECT-18791363
[Presentation] Gingipainはprotease-activated receptorの活性化を介して、Weibel-Palade小体のエキソサイトーシスを誘導し、血管内皮細胞の炎症応答を増強する2007
- Author(s)
  猪俣恵、引頭毅、中島美砂子、野口俊英、松下健二
- Organizer
  第49回歯科基礎医学会総会
- Place of Presentation
  札幌
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-19659494
[Presentation] Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors2007
- Author(s)
  Inomata M, Into T, Nakashima M, Noguchi T, Matsushita K
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji, Japan
- Year and Date
  2007-09-04
- Data Source
  KAKENHI-PROJECT-19390538
[Presentation] オートファジーによるToll様受容体を介した細胞内シグナル伝達の調節
- Author(s)
  猪俣恵, 引頭毅
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] マウス唾液腺における抗菌性因子産生におけるシグナル伝達分子MyD88の役割の検討
- Author(s)
  引頭　毅、猪俣　恵、稲葉裕明、村上幸孝、柴田健一郎
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-27 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26462803
[Presentation] シグナル伝達分子MyD88 は顎下腺におけるB-1 細胞浸潤の制御と唾液中の抗体産生の調節に関与する
- Author(s)
  引頭毅, 滝川俊也, 柴田健一郎
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] Myd88 deficiency causes acumulation of B-1a cells in submandibular glands
- Author(s)
  Into T., Inomata, M., and Shibata K.
- Organizer
  The 41st Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] Regulation of Toll-like receptor signaling by human NDP52-mediated selective autophagy
- Author(s)
  Inomata, M., Shibata K., and Into T
- Organizer
  The 40th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy
- Author(s)
  Inomata, M., and Into T.
- Organizer
  The 6th International Symposium on Autophagy
- Place of Presentation
  万国津梁館（沖縄県名護市）
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] Myd88 deficiency suppresses acumulation of B-1a cells in submandibular glands
- Author(s)
  Into T., Inomata, M., and Shibata K
- Organizer
  The 41st Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] TLR シグナルを制御するオートファジー受容体
- Author(s)
  引頭毅
- Organizer
  第79回日本細菌学会北海道支部学術懇談会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] 歯周病関連細菌Porphyromonas gingivalisから同定された糖蛋白質の増殖およびバイオフィルム形成への関与
- Author(s)
  村上幸孝、長谷川義明、引頭毅、猪俣恵
- Organizer
  第42回東海乳酸菌研究会研究報告会
- Place of Presentation
  中日パレス（名古屋市）
- Data Source
  KAKENHI-PROJECT-23592720
[Presentation] NDP52 は選択的オートファジーの誘導によってToll 様受容体シグナルを負に制御する
- Author(s)
  猪俣恵, 新飯田俊平, 柴田健一郎, 引頭毅
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy
- Author(s)
  Inomata, M., and Into T
- Organizer
  The 6th International Symposium on Autophagy
- Place of Presentation
  Okinawa
- Data Source
  KAKENHI-PROJECT-23390431
[Presentation] 抗菌ペプチドLL-37 は異種のToll 様受容体リガンドによる歯肉線維芽細胞の応答に対して異なる効果を発揮する
- Author(s)
  引頭毅, 猪俣恵, 柴田健一郎, 村上幸孝
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23390431

1. MATSUSHITA Kenji (90253898)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
2. TAKIGAWA Toshiya (90263095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. INOMATA Megumi (40553798)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
4. 片岡嗣雄 (60451390)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. 森大気 (10743544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. YAGI Takakazu (10346166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIYAWAKI Shouichi (80295807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUGUCHI Tetsuya (10303629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KITAI Noriyuki (20271025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKAYAMA Eiji (70533446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. SHIBATA Ken-ichiro (50145265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
12. MURAKAMI Yukitaka (60239506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. YOSHIMURA Fuminobu (50001962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HASEGAWA Yoshiaki (70460524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. TAKAGI Shuta (10711351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. SUGIYAMA Akiko (90304534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Into Takeshi 引頭 毅

引頭 毅 イントウ タケシ

INTO Takeshi 引頭 毅

Research Projects

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Co-Researchers

歯垢マトリックスの未解明領域の探求と新たな歯垢制御戦略Principal Investigator

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Analysis of the role of phosphatidylserine-binding proteins accumulated in dental plaque and their relevance to the onset of periodontitisPrincipal Investigator

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GBPsによるLPS認識が歯周炎ならびに炎症性腸疾患に及ぼす病因的役割の解明

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The commander of autoimmune sialadenitis: regulatory mechanisms of tertiary lymphoid tissue formation by MyD88-dependent signalingPrincipal Investigator

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Study on the regulatory mechanisms of production of antimicrobial factors in salivary grands by the vesicular transport protein intersectinPrincipal Investigator

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Elucidation of the mechanism to improve the cleft palate phenotype with the molecular target drug

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Regulatory effect of the TLR/TACI-MyD88 signaling pathway on immune responses associated with the homing of IgA-producing B cells into salivary glandsPrincipal Investigator

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Post-translational modifications of proteins from periodontpathic bacteria: role of glycosylation and phosphorylation

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Investigation of stretch-induced intracellular signal transduction in human periodontal ligament fibroblasts exposed to periodontopathic factors.

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口腔自然免疫機構における多量体型免疫グロブリン受容体pIgRの役割の解明Principal Investigator

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一酸化窒素による細菌感染時応答の時間的・空間的制御機構の解明Principal Investigator

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Development of new therapy for periodontal disease based on regulating exocytosis

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歯肉上皮機能の分子機構の解明とその制御に関する研究

Principal Investigator

Into Takeshi 引頭毅

引頭毅イントウタケシ

INTO Takeshi 引頭毅