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Sera Takashi  世良 貴史

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… Alternative Names

SERA Takashi  世良 貴史

TAKAHASHI Sera  世良 貴史

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Researcher Number 10362443
Other IDs
Affiliation (Current) 2025: 岡山大学, ヘルスシステム統合科学学域, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 岡山大学, ヘルスシステム統合科学学域, 教授
2018 – 2019: 岡山大学, ヘルスシステム統合科学研究科, 教授
2012 – 2017: 岡山大学, 自然科学研究科, 教授
2012: 京都大学, 大学院・工学研究科, 准教授
2011: 岡山大学, 大学院・自然科学研究科, 教授 … More
2010: 京都大学, 工学研究科, 准教授
2007: Kyoto University, 工学研究科, 准教授
2004 – 2006: 京都大学, 工学研究科, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Chemistry related to living body / Basic Section 37010:Bio-related chemistry / Tumor therapeutics / Plant protection science
Except Principal Investigator
Respiratory surgery / Functional biochemistry
Keywords
Principal Investigator
遺伝子発現 / タンパク質 / RNA / 遺伝子 / DNA結合タンパク質 / 転写因子 / 遺伝子導入 / DNA-binding protein / Inhibition of replication / DNA virus … More / 複製阻害 / DNAウイルス / 植物DNAウイルス / ウイルス耐病性 / iPS細胞 / バイオテクノロジー / 発現制御 / 血管内皮増殖因子 / がん / セレクション / ライブラリー / 人工DNA結合タンパク質 / 人工転写因子 … More
Except Principal Investigator
分子標的治療 / 肺外科 / 人口転写因子 / Sox2 / 肺扁平上皮癌 / 酵素反応 / 理論計算 / X線結晶解析 / 酵素の触媒機構 / B_<12>補酵素 / 酵素 / B12補酵素 / システム酵素学 / 立体構造 / 活性化蛋白質 / 再活性化因子 / 酵素反応機構 / S-アデノシルメチオニン / B_12補酵素 / ラジカル酵素 Less
  • Research Projects

    (13 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (10 People)
  •  新規人工RNA結合タンパク質の革新的デザイン法の開発とその有効性の検証Principal Investigator

    • Principal Investigator
      世良 貴史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      Okayama University
  •  Development of innovative design method for new artificial RNA-binding proteinsPrincipal Investigator

    • Principal Investigator
      Sera Takashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      Okayama University
  •  Development of a site-specific gene integration method to human genomesPrincipal Investigator

    • Principal Investigator
      Sera Takashi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      Okayama University
  •  Development of artificial transcription factors for the treatment of lung and esophageal squamous cell carcinoma

    • Principal Investigator
      Naomoto Yoshio
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Kawasaki Medical School
  •  Generation of plants resistant to DNA viruses using artificial DNA-binding proteinsPrincipal Investigator

    • Principal Investigator
      SERA TAKASHI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plant protection science
    • Research Institution
      Okayama University
  •  Development of a global gene identification methodPrincipal Investigator

    • Principal Investigator
      SERA TAKASHI
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Chemistry related to living body
    • Research Institution
      Okayama University
  •  Studies of action mechanisms of radical enzyme systems for providing new paradigms of enzyme researches

    • Principal Investigator
      TORAYA Tetsuo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Okayama University
  •  Improvement of production efficiency of iPS cellsPrincipal Investigator

    • Principal Investigator
      SERA Takashi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Chemistry related to living body
    • Research Institution
      Okayama University
      Kyoto University
  •  人工転写因子ライブラリーを用いた網羅的遺伝子同定Principal Investigator

    • Principal Investigator
      世良 貴史
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  人工転写因子を用いたがん増殖シグナルの人為的操作Principal Investigator

    • Principal Investigator
      世良 貴史
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  人工転写因子ライブラリーを用いた網羅的遺伝子同定Principal Investigator

    • Principal Investigator
      世良 貴史
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  A novel approach to inhibition of human virus infection : inhibition of DNA virus replication by artificial DNA-binding proteinsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Sera
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Kyoto University
  •  人工転写因子ライブラリーを用いた網羅的遺伝子同定Principal Investigator

    • Principal Investigator
      世良 貴史
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University

All 2024 2023 2021 2018 2017 2006

All Journal Article Presentation Book Patent

  • [Book] 化学フロンティア ゲノム化学(第5章を担当)2006

    • Author(s)
      世良 貴史
    • Total Pages
      6
    • Publisher
      化学同人
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17550154
  • [Journal Article] Necessity of flanking repeats R1′ and R8′ of human Pumilio1 protein for RNA binding2021

    • Author(s)
      K. Nakamura, T. Nakao, T. Mori, S. Ohno, Y. Fujita, K. Masaoka, K. Sakabayashi, K. Mori, T. Tobimatsu, T. Sera*
    • Journal Title

      Biochemistry

      Volume: 60 Issue: 40 Pages: 3007-3015

    • DOI

      10.1021/acs.biochem.1c00445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02834
  • [Journal Article] Site-Specific Integration by Recruitment of a Complex of ΦC31 Integrase and Donor DNA to a Target Site by Using a Tandem, Artificial Zinc-Finger Protein.2018

    • Author(s)
      Sumikawa T, Ohno S, Watanabe T, Yamamoto R, Yamano M, Mori T, Mori K, Tobimatsu T, Sera T
    • Journal Title

      Biochemistry

      Volume: 57 Issue: 50 Pages: 6868-6877

    • DOI

      10.1021/acs.biochem.8b00979

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14237, KAKENHI-PROJECT-16K14633
  • [Journal Article] Inhibition of DNA replication of human papillomavirus by artificial zinc-finger proteins2006

    • Author(s)
      Takashi Mino, Takeaki Hatono, Naoki Matsumoto, Tomoaki Mori, Yusuke Mineta, Yasuhiro Aoyama, Takashi Sera*
    • Journal Title

      Journal of Virology 80・11(印刷中のため未定)

    • Data Source
      KAKENHI-PROJECT-17550154
  • [Journal Article] Application of artificial zinc-finger proteins to inhibition of DNA replication of human papillomaviruses2006

    • Author(s)
      T.Mino, T.Mori, N.Matsumoto, Y.Mineta, T.Okamoto, Y.Aoyama, T.Sera
    • Journal Title

      Nucleic Acid Symposium Series 50

      Pages: 313-313

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17550154
  • [Journal Article] Inhibition of DNA replication of human papillomavirus by artificial zinc finger proteins2006

    • Author(s)
      T.Mino, T.Hatono, N.Matsumoto, T.Mori, Y.Mineta, Y.Aoyama, T.Sera
    • Journal Title

      Journal of Virology 80

      Pages: 5405-5405

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17550154
  • [Journal Article] Frontier of Chemistry : Genomic Chemistry2006

    • Author(s)
      T.Sera
    • Journal Title

      Kagakudoujin 6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17550154
  • [Journal Article] Application of artificial zinc-finger proteins to inhibition of DNA replication of human papillomaviruses2006

    • Author(s)
      T.Mino, T.Mori, N.Matsumoto, Y.Mineta, T.Okamoto, Y.Aoyama, T.Sera
    • Journal Title

      Nucleic Acids Symposium Series 50

      Pages: 313-313

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17550154
  • [Patent] 扁平上皮癌に対する抗腫瘍剤2017

    • Inventor(s)
      猶本 良夫、深澤 拓也、世良 貴史
    • Industrial Property Rights Holder
      学校法人川崎学園
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-038047
    • Filing Date
      2017-03-01
    • Data Source
      KAKENHI-PROJECT-26462141
  • [Presentation] 人工RNA結合タンパク質の創出2024

    • Author(s)
      山部 靖治、浮田 康平、吉岡 健太、長尾 桂輔、毛利 隼大、森 友明、森 光一、世良 貴史
    • Organizer
      日本化学会 第104春季年会
    • Data Source
      KAKENHI-PROJECT-23K23467
  • [Presentation] 人工RNA結合タンパク質のデザイン法の開発2023

    • Author(s)
      山部 靖治、門家 拓哉、仲尾 太秀、森 友明、森 光一、世良 貴史
    • Organizer
      第37回中国四国ウイルス研究会
    • Data Source
      KAKENHI-PROJECT-23K23467
  • [Presentation] RNAウイルス不活性化のための人工RNA結合タンパク質のセレクション2023

    • Author(s)
      岡 千裕、大石 竜士、浮田 康平、森 友明、森 光一、世良 貴史
    • Organizer
      第37回中国四国ウイルス研究会
    • Data Source
      KAKENHI-PROJECT-23K23467
  • [Presentation] 翻訳抑制に基づいた人工RNA結合タンパク質のセレクション系の構築と検証2023

    • Author(s)
      天滿 詩絵奈、今城 美久、大石 竜士、森 友明、森 光一、世良 貴史
    • Organizer
      第37回中国四国ウイルス研究会
    • Data Source
      KAKENHI-PROJECT-23K23467
  • [Presentation] 人工DNA結合タンパク質を用いた位置特異的遺伝子導入法の開発2017

    • Author(s)
      河田 隆宏、住川 達彦、王野 瀬里香、森 知明、森 光一、飛松 孝正、世良 貴史
    • Organizer
      第11回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16K14633
  • 1.  TORAYA Tetsuo (70026318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  TOBIMATSU Takamasa (30188768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  MORI Koichi (50379715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  YOSHIZAWA Kazunari (30273486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SHIBATA Naoki (30295753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Naomoto Yoshio (00237190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  深澤 拓也 (20379845)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  山辻 知樹 (40379730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  高岡 宗徳 (50548568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  羽井佐 実 (70322229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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