NAKAO Ryoma 中尾龍馬

Researcher Number	10370959
Other IDs	https://orcid.org/0000-0002-4802-8518
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所細菌第一部, 室長
Affiliation (based on the past Project Information) *help	2016 – 2024: 国立感染症研究所, 細菌第一部, 主任研究官 2012 – 2015: 国立感染症研究所, その他部局等, 主任研究官 2013: 国立感染症研究所, その他部局等, 研究員 2013: 国立感染症研究所, 細菌第一部 2013: 国立感染症研究所, 細菌第一部, 主任研究官 … More 2012: 国立感染症研究所, 細菌第一部, 研究員 2010 – 2011: 国立感染症研究所, 細菌第一部, 主任研究官 2010: 国立感染症研究所, 主任研究官 2008: 感染研, 研究員 2007: National Institute of Infectious Diseases, 細菌第1部, 主任研究官 2004 – 2006: 国立感染症研究所, 細菌第一部, 研究員 Less
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Medium-sized Section 57:Oral science and related fields / Basic Section 57020:Oral pathobiological science-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Morphological basic dentistry Except Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 54030:Infectious disease medicine-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 38060:Applied molecular and cellular biology-related / Basic Section 57030:Conservative dentistry-related / Basic Section 57080:Social dentistry-related / Morphological basic dentistry
Keywords	Principal Investigator 歯周病 / 細菌由来膜小胞 / 細菌膜小胞 / 外膜小胞 / ワクチン / 外膜ヴェシクル / Porphyromonas gingivalis / 膜小胞 / 粘膜免疫 / LPS … More / small RNA / 慢性炎症 / 膵臓がん / 細菌由来外膜小胞 / 歯周病原細菌 / Outer membrane vesicles / ナノ粒子ワクチン / ワクチンの安全性評価 / 免疫 / O結合型グリコシレーション / P. gingivalis / HagB / 糖タンパク / ヘマグルチニン / Porhyrmonas gingivalis / 大腸菌 / 細菌 / バイオフィルム / 外膜タンパク / galE / 抗菌治療薬療法 / ミノサイクリン / 遺伝子トランスファー / Tn916 / テトラサイクリン / 歯科用ミノサイクリン軟膏 / テトラサイクリン類 / トランスポゾン / 抗菌薬療法 / 薬剤耐性 / レンサ球菌 / tetM … More Except Principal Investigator 膜小胞 / バイオフィルム / ワクチン / 歯周病 / コラーゲン / CSP / RT-PCR / Streptococcus mutans / 唾液分泌低下 / カルボキシメチルアルギニン（CMA） / 歯周病菌（Pg） / 糖化終末化合物（AGEｓ） / 自然免疫 / 自然免疫記憶 / 肺炎球菌 / 経鼻接種 / 百日咳 / 免疫学的指標 / 相関 / 感染防御能 / 歯周病原菌 / 食品素材 / ウイキョウ / グリーンルイボス / ホップ / プレニルフラボノイド / ペトロセリン酸 / ウィキョウ / quercetinラムノース配糖体 / (-)-catechin / mahanimbine / プレニル化四環カルバゾールアルカロイド / ノブドウ / カレーリーフ / 糖化最終生成物 / 歯周病菌 / AGEs / ポリフェノール / プレニル誘導体 / CMA / Porphyromonas gingivalis / 糖化 / 宿主細胞 / サイトカイン / カルジオリピン / マクロファージ / 緑膿菌 / 慢性炎症 / 細菌 / メンブレンヴェシクル / Pg / Porphyromonus gingivalis / 口腔マイクロビオータ / 腸内マイクロビオータ / ランチビオテックスバクテリオシン / ランチビオティクスバクテリオシン / ランチビオテクス / Streptocpccus mutans / 蛋白質 / eDNA / ナノファイバー / シャペロン / DNA / グルコシルトランスフェラーゼ / クオラムセンシング / 細胞外DNA / Staphylococcus aureus / フローセル / 口腔常在菌 / 日和見菌 / Biofilm / bacitracin transport ATP-binding protein bcrA / Flow cell system / DNA micro array / quorum sensing (QS) system / oral biofilm / mutans streptococci / ->マウス / NOD.E2F-1^<- / NOD.B10.D2マウス / E2F-1^<-->マウス / mRNA / バクテリオシン分泌蛋白質遺伝子 / パルスフィールド電気泳動 / ミュータンス連鎖球菌 / Competence stimulating peptide(CSP) / クオラムセンシング(QS)システム / バシトラシン輸送ATP結合蛋白質bcrA / フローセルシステム / DNAマイクロアレイ / クオラムセンシング(QS)シ / 口腔バイオフィルム / ミュータンスレンサ球菌 / 異常タンパク質 / コンゴ―レッド / S, gordonii / 病原性 / S. gordonii / SMU574 / SMU482 / 異常蛋白質 / コンゴーレッド / 遺伝子 / S. mutans / アミロイド / -> / SCID, E2f-1^<- / NOD / NOD/SCID,E2f-1 / フルクタナーゼ / IgA / NOD/SCID, E2f-1^<-/-> / Streptococcus gordonii / う蝕予防 / ペプチド / 抑制物質 Less

Search for natural compounds with anti-periodontal pathogens and anti-glycation activity to prevent and ameliorate periodontal disease-related systemic diseases.
- Principal Investigator
  
  池田剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Sojo University
Analysis of immune responses induced by intranasal administration of B. pertussis vaccine candidates
- Principal Investigator
  
  相内章
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  National Institute of Infectious Diseases
Creation of a vaccine platform with innate immune activation
- Principal Investigator
  
  木村聡一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  湘南医療大学
Acceleration of unexplored periodontal disease vaccine development by intranasal administration of bacterial membrane vesiclesPrincipal Investigator
- Principal Investigator
  
  中尾龍馬
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  National Institute of Infectious Diseases
Dynamic behavior and pathological significance of small RNA in outer membrane vesicles of periodontopathic bacteriaPrincipal Investigator
- Principal Investigator
  
  中尾龍馬
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  National Institute of Infectious Diseases
The development of high-snsitivity detection system of bacteria-derived membrane vesicle and detection of membrane vesicle in the chronic inflamatory vascular deseases
- Principal Investigator
  
  Miyazaki Hidetaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Aichi Medical University
  Oita University
Periodontopathic bacterial outer membrane vesicles: Biogenesis and relation to development of chronic inflammation and carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Nakao Ryoma
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  National Institute of Infectious Diseases
Exploratory research on prenyl derivatives with anti-glycation and anti-periodontopathogenic activity to prevent and ameliorate periodontal disease-related conditions.
- Principal Investigator
  
  Ikeda Tsuyoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Sojo University
Novel nano paticle vaccine | Biogenesis and medical application of outer membrane vesiclesPrincipal Investigator
- Principal Investigator
  
  Nakao Ryoma
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Institute of Infectious Diseases
Membrane vesicle-mediated infection strategy at the bacteria-host cell interface
- Principal Investigator
  
  TASHIRO YOSUKE
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Shizuoka University
Effect of lantibiotics bacteriocin produced by oral bacteria on intestinal microbiota
- Principal Investigator
  
  Yonezawa Hideo
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Kyorin University
Study of pathogenic biofilm formation by extracellular nucleic acid, nanofiber and chaperone
- Principal Investigator
  
  Senpuku Hidenobu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute of Infectious Diseases
Immunopathology of outer membrane vesicles of periodontopathic bacteriaPrincipal Investigator
- Principal Investigator
  
  NAKAO Ryoma
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute of Infectious Diseases
Study of oral biofilm associated with bacterial surface amyloid
- Principal Investigator
  
  SENPUKU Hidenobu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  National Institute of Infectious Diseases
Investigation of biofilm-related molecules in Porphyromonas gingivalisPrincipal Investigator
- Principal Investigator
  
  NAKAO Ryoma
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute of Infectious Diseases
Development of control system for pathogenic oral biofilm using compound and new proteins
- Principal Investigator
  
  SENPUKU Hidenobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute of Infectious Diseases
Porphyromonas gingivalisの外膜ヴェシクル産生メカニズムPrincipal Investigator
- Principal Investigator
  
  中尾龍馬
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  National Institute of Infectious Diseases
歯周病に対する長期の局所抗菌薬療法に伴う口腔細菌の薬剤耐性化に関する研究Principal Investigator
- Principal Investigator
  
  中尾龍馬
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute of Infectious Diseases
Molecular analyses and identifications of new genes to infectious diseases relating with oral biofilm
- Principal Investigator
  
  SENPUKU Hidenobu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Institute of Infectious Diseases

[Book] Methods in Molecular Biology: Glycine Induction Method: Effective Production of Immunoactive Bacterial Membrane Vesicles with Low Endotoxin Content2022
- Author(s)
  Hirayama S, Nakao R.
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-20H03861
[Book] Methods in Molecular Biology: Glycine Induction Method: Effective Production of Immunoactive Bacterial Membrane Vesicles with Low Endotoxin Content2022
- Author(s)
  Hirayama S, Nakao R.
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-21KK0164
[Book] Methods in Molecular Biology: Glycine Induction Method: Effective Production of Immunoactive Bacterial Membrane Vesicles with Low Endotoxin Content2022
- Author(s)
  Hirayama S, Nakao R.
- Total Pages
  10
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-19K22644
[Book] Methods in Molecular Biology: Glycine Induction Method: Effective Production of Immunoactive Bacterial Membrane Vesicles with Low Endotoxin Content2022
- Author(s)
  Hirayama S, Nakao R.
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-21K18284
[Book] Methods in Molecular Biology: Intranasal vaccine study using Porphyromonas gingivalis membrane vesicles: isolation method and application to a mouse model2021
- Author(s)
  Hirayama S, Nakao R.
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-21KK0164
[Book] Methods in Molecular Biology: Intranasal vaccine study using Porphyromonas gingivalis membrane vesicles: isolation method and application to a mouse model2021
- Author(s)
  Hirayama S, Nakao R.
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-21K18284
[Book] Methods in Molecular Biology: Intranasal vaccine study using Porphyromonas gingivalis membrane vesicles: isolation method and application to a mouse model2021
- Author(s)
  Hirayama S, Nakao R.
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-20H03861
[Book] Methods in Molecular Biology: Intranasal vaccine study using Porphyromonas gingivalis membrane vesicles: isolation method and application to a mouse model2021
- Author(s)
  Hirayama S, Nakao R.
- Total Pages
  10
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-19K22644
[Journal Article] Biofilm-derived membrane vesicles exhibit potent immunomodulatory activity in Pseudomonas aeruginosa PAO12024
- Author(s)
  Minato Takahara, Satoru Hirayama, Hiroyuki Futamata,Ryoma Nakao, Yosuke Tashiro
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 未定
- Data Source
  KAKENHI-PROJECT-21KK0164
[Journal Article] Development of selective isolation media for detecting Actinomyces and Schaalia genera from oral specimens containing indigenous bacteria2024
- Author(s)
  Sadao Aoki, Hiroko Yahara, Ryoma Nakao, Osamu Tsuzukibashi, Koji Yahara
- Journal Title
  
  Access Microbiology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03861
[Journal Article] Mucosal adjuvanticity and mucosal booster effect of colibactin-depleted probiotic <i>Escherichia coli</i> membrane vesicles2024
- Author(s)
  Uchiyama Hiroki、Kudo Toshifumi、Yamaguchi Takehiro、Obana Nozomu、Watanabe Kenji、Abe Kimihiro、Miyazaki Hidetaka、Toyofuku Masanori、Nomura Nobuhiko、Akeda Yukihiro、Nakao Ryoma
- Journal Title
  
  Human Vaccines & Immunotherapeutics
  
  Volume: 20 Issue: 1 Pages: 2337987-2337987
- DOI
  10.1080/21645515.2024.2337987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-21KK0164, KAKENHI-PROJECT-22K05400, KAKENHI-PROJECT-20H03861, KAKENHI-PROJECT-23K26811
[Journal Article] Multimodal Inhibitory Effect of Matcha on Porphyromonas gingivalis2024
- Author(s)
  Ryoma Nakao, Ayami Takatsuka, Kengo Mandokoro, Naoki Narisawa, Tsuyoshi Ikeda, Hideki Takai, Yorimasa Ogata
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 未定
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03861
[Journal Article] Multimodal Inhibitory Effect of Matcha on Porphyromonas gingivalis2024
- Author(s)
  Ryoma Nakao, Ayami Takatsuka, Kengo Mandokoro, Naoki Narisawa, Tsuyoshi Ikeda, Hideki Takai, Yorimasa Ogata
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 未定
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18284
[Journal Article] Biofilm-derived membrane vesicles exhibit potent immunomodulatory activity in Pseudomonas aeruginosa PAO12024
- Author(s)
  Minato Takahara, Satoru Hirayama, Hiroyuki Futamata,Ryoma Nakao, Yosuke Tashiro
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18284
[Journal Article] Development of selective isolation media for detecting Actinomyces and Schaalia genera from oral specimens containing indigenous bacteria2024
- Author(s)
  Sadao Aoki, Hiroko Yahara, Ryoma Nakao, Osamu Tsuzukibashi, Koji Yahara
- Journal Title
  
  Access Microbiology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21KK0164
[Journal Article] Biofilm-derived membrane vesicles exhibit potent immunomodulatory activity in Pseudomonas aeruginosa PAO12024
- Author(s)
  Minato Takahara, Satoru Hirayama, Hiroyuki Futamata,Ryoma Nakao, Yosuke Tashiro
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03861
[Journal Article] Multimodal Inhibitory Effect of Matcha on Porphyromonas gingivalis2024
- Author(s)
  Ryoma Nakao, Ayami Takatsuka, Kengo Mandokoro, Naoki Narisawa, Tsuyoshi Ikeda, Hideki Takai, Yorimasa Ogata
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 未定
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0164
[Journal Article] Identification of genes involved in enhanced membrane vesicle formation in Pseudomonas aeruginosa biofilms: Surface sensing facilitates vesiculation2024
- Author(s)
  Sadao Aoki, Hiroko Yahara, Ryoma Nakao, Osamu Tsuzukibashi, Koji Yahara
- Journal Title
  
  Access Microbiology
  
  Volume: 未定
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18284
[Journal Article] Identification of genes involved in enhanced membrane vesicle formation in Pseudomonas aeruginosa biofilms: surface sensing facilitates vesiculation2023
- Author(s)
  Kanno Mizuki、Shiota Takuya、Ueno So、Takahara Minato、Haneda Keisuke、Tahara Yuhei O.、Shintani Masaki、Nakao Ryoma、Miyata Makoto、Kimbara Kazuhide、Futamata Hiroyuki、Tashiro Yosuke
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 14 Pages: 1252155-1252155
- DOI
  10.3389/fmicb.2023.1252155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-21KK0164, KAKENHI-PROJECT-20H03861
[Journal Article] A bivalent outer membrane vesicle-based intranasal vaccine to prevent infection of periodontopathic bacteria2023
- Author(s)
  Nakao Ryoma、Hirayama Satoru、Yamaguchi Takehiro、Senpuku Hidenobu、Hasegawa Hideki、Suzuki Tadaki、Akeda Yukihiro、Ohnishi Makoto
- Journal Title
  
  Vaccine
  
  Volume: 41 Issue: 30 Pages: 4369-4383
- DOI
  10.1016/j.vaccine.2023.05.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-21KK0164
[Journal Article] Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis2022
- Author(s)
  Nanami Yoshino; Tsuyoshi Ikeda; Nakao Ryoma
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644
[Journal Article] Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis2022
- Author(s)
  Nanami Yoshino; Tsuyoshi Ikeda; Nakao Ryoma
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-21KK0164
[Journal Article] Scanning Electron Microscopy of Escherichia coli Encapsulated in a Spacerized Graphene Sandwich2022
- Author(s)
  Sasaki, Yuki; Hirayama, Satoru; Nakao, Ryoma
- Journal Title
  
  Microscopy
  
  Volume: in press Issue: 3 Pages: 175-180
- DOI
  10.1093/jmicro/dfac010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22644, KAKENHI-PROJECT-20H03861, KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-21KK0164, KAKENHI-PROJECT-19K15404
[Journal Article] Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis2022
- Author(s)
  Nanami Yoshino; Tsuyoshi Ikeda; Nakao Ryoma
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18284
[Journal Article] Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis2022
- Author(s)
  Yoshino Nanami、Ikeda Tsuyoshi、Nakao Ryoma
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 13 Pages: 816047-816047
- DOI
  10.3389/fmicb.2022.816047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07122, KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-21KK0164
[Journal Article] Scanning Electron Microscopy of Escherichia coli Encapsulated in a Spacerized Graphene Sandwich2022
- Author(s)
  Sasaki, Yuki; Hirayama, Satoru; Nakao, Ryoma
- Journal Title
  
  Microscopy
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-21KK0164
[Journal Article] Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis2022
- Author(s)
  Nanami Yoshino; Tsuyoshi Ikeda; Nakao Ryoma
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03861
[Journal Article] A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles2022
- Author(s)
  Nakao Ryoma、Kobayashi Hirotaka、Iwabuchi Yusuke、Kawahara Kazuyoshi、Hirayama Satoru、Ramstedt Madeleine、Sasaki Yuki、Kataoka Michiyo、Akeda Yukihiro、Ohnishi Makoto
- Journal Title
  
  npj Vaccines
  
  Volume: 7 Issue: 1 Pages: 13-13
- DOI
  10.1038/s41541-022-00572-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-22K20988, KAKENHI-PROJECT-21KK0164, KAKENHI-PROJECT-19K15404
[Journal Article] Glycine Induction Method: Effective Production of Immunoactive Bacterial Membrane Vesicles with Low Endotoxin Content2021
- Author(s)
  Satoru Hirayama, Ryoma Nakao
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2414 Pages: 207-226
- DOI
  10.1007/978-1-0716-1900-1_13
- ISBN
  9781071618998, 9781071619001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18492, KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-21KK0164
[Journal Article] Effects of oral moisturizing gel containing propolis following head and neck radiotherapy: randomized controlled pilot trial2021
- Author(s)
  Ryoma Nakao, Takao Ueno
- Journal Title
  
  BDJ Open
  
  Volume: 7 Issue: 10 Pages: 12-12
- DOI
  10.3390/pathogens10101286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644, KAKENHI-PROJECT-20H03861, KAKENHI-PROJECT-20K07122, KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-20K09943
[Journal Article] Effects of pH on the properties of membrane vesicles including glucosyltransferase in Streptococcus mutans2021
- Author(s)
  Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku
- Journal Title
  
  Microorganisms
  
  Volume: 9 Issue: 11 Pages: 2308-2308
- DOI
  10.3390/microorganisms9112308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644, KAKENHI-PROJECT-20H03861, KAKENHI-PROJECT-20K10286, KAKENHI-PROJECT-21K18284, KAKENHI-PROJECT-20K09943
[Journal Article] Effects of oral moisturizing gel containing propolis following head and neck radiotherapy: randomized controlled pilot trial2021
- Author(s)
  Ryoma Nakao and Takao Ueno
- Journal Title
  
  BDJ Open
  
  Volume: 7 Issue: 1 Pages: 12-12
- DOI
  10.1038/s41405-021-00068-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644, KAKENHI-PROJECT-20K09943
[Journal Article] Roles of membrane vesicles from Streptococcus mutans for the induction of antibodies to glucosyltransferase in mucosal immunity2020
- Author(s)
  Nakamura Tomoyo、Iwabuchi Yusuke、Hirayama Satoru、Narisawa Naoki、Takenaga Fumio、Nakao Ryoma、Senpuku Hidenobu
- Journal Title
  
  Microbial Pathogenesis
  
  Volume: 149 Pages: 104260-104260
- DOI
  10.1016/j.micpath.2020.104260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10286, KAKENHI-PROJECT-19K22644
[Journal Article] Effect of topical administration of propolis in chronic periodontitis2020
- Author(s)
  Nakao R, Senpuku H, Ohnishi M, Takai H, Ogata Y.
- Journal Title
  
  Odontology
  
  Volume: 1 Issue: 4 Pages: 1-1
- DOI
  10.1007/s10266-020-00500-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22644
[Journal Article] Glycine Significantly Enhances Bacterial Membrane Vesicle Production: A Powerful Approach for Isolation of LPS-reduced Membrane Vesicles of Probiotic Escherichia Coli2020
- Author(s)
  Satoru Hirayama, Ryoma Nakao
- Journal Title
  
  Microb Biotechnol
  
  Volume: 13 Issue: 4 Pages: 1162-1178
- DOI
  10.1111/1751-7915.13572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644, KAKENHI-PROJECT-18K15160
[Journal Article] Glycine significantly enhances bacterial membrane vesicle production: a powerful approach for isolation of LPS-reduced membrane vesicles of probiotic Escherichia coli2020
- Author(s)
  Satoru Hirayama and Ryoma Nakao
- Journal Title
  
  Microbial Biotechnology
  
  Volume: 13 Pages: 1162-1178
- DOI
  10.1007/978-1-0716-0939-2_15
- ISBN
  9781071609385, 9781071609392
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644
[Journal Article] The Inhibitory Effects of Polypyrrole on the Biofilm Formation of Streptococcus Mutans2019
- Author(s)
  Senpuku H, Tuna EB, Nagasawa R, Nakao R, Ohnishi M.
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 11 Pages: 1-1
- DOI
  10.1371/journal.pone.0225584
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644
[Journal Article] Effects of Complex DNA and MVs With GTF Extracted From Streptococcus mutans on the Oral Biofilm2019
- Author(s)
  Senpuku H, Nakamura T, Iwabuchi Y, Hirayama S, Nakao R, Ohnishi M
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 17 Pages: 1-1
- DOI
  10.3390/molecules24173131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22644
[Journal Article] 高速原子間力顕微鏡を用いた細菌の形態変化の観察 ―プロポリスが歯周病原細菌Porphyromonas gingivalisに及ぼす抗菌作用2019
- Author(s)
  平山悟、吉益由莉、中尾龍馬
- Journal Title
  
  顕微鏡/KENBIKYO
  
  Volume: 54 Pages: 72-76
- NAID
  130007704154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22644
[Journal Article] Immunoactive clostridial membrane vesicle production is regulated by a sporulation factor2017
- Author(s)
  Obana N, Nakao R, Nagayama K, Nakamura K, Senpuku H, Nomura N.
- Journal Title
  
  Infection and immunity
  
  Volume: 21;85(5) Issue: 5
- DOI
  10.1128/iai.00096-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462866
[Journal Article] Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenylated flavonoids2016
- Author(s)
  Toru Kariua, Ryoma Nakao, Tsuyoshi Ikeda, Keisuke Nakashima, Jan Potempa, and Takahisa Imamura
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 未定 Issue: 1 Pages: 89-96
- DOI
  10.1111/jre.12372
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866, KAKENHI-PROJECT-16K08741
[Journal Article] Assessment of outer membrane vesicles of periodontopathic bacterium Porphromonas gingivalis as possible mucosal immunogen2016
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Bai Dongying Makoto Ohnish, Hidenobu Senpuku.
- Journal Title
  
  Vaccine
  
  Volume: 34 Pages: 4626-34
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462866
[Journal Article] Immunoreactive antigens recognized in serum samples from mice intranasally immunized with Porphyromonas gingivalis outer membrane vesicles2015
- Author(s)
  Bai D, Nakao R, Ito A, Uematsu H, Senpuku H
- Journal Title
  
  Pathogens and Disease
  
  Volume: 73(3) Issue: 3
- DOI
  10.1093/femspd/ftu006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462866
[Journal Article] Effect of Porphyromonas gingivalis outer membrane vesicles on gingipain mediated detachment of cultured oral epithelial cells and immune responses2014
- Author(s)
  Ryoma Nakao, Shogo Takashiba, Saori Kosonoc, Minoru Yoshida, Haruo Watanabe, Makoto Ohnishi, Hidenobu Senpuku
- Journal Title
  
  Micr obes and Infection
  
  Volume: 16 Pages: 6-16
- Data Source
  KAKENHI-PROJECT-24659821
[Journal Article] A novel approach for purification and selective capture of membrane vesicles of the periodontopathic bacterium, Porphyromonas gingivalis: membrane vesicles bind to magnetic beads coated with epoxy groups in a noncovalent, species-specific manner.2014
- Author(s)
  Nakao R, Kikushima K, Higuchi H, Obana N, Nomura N, Bai D, Ohnishi M, Senpuku H.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 5 Pages: 1-10
- DOI
  10.1371/journal.pone.0095137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J00321, KAKENHI-PROJECT-22791822, KAKENHI-PROJECT-23247022, KAKENHI-PROJECT-25650105, KAKENHI-PROJECT-26462866, KAKENHI-PROJECT-26860281, KAKENHI-PLANNED-23107002
[Journal Article] Effect of Porphyromonas gingivalis outer membrane vesicles on gingipain-mediated detachment of cultured oral epithelial cells and immune responses2014
- Author(s)
  Nakao R, Takashiba S, Kosono S, Yoshida M, Watanabe H, Ohnishi M, Senpuku H.
- Journal Title
  
  Microbes and Infection
  
  Volume: 16 Issue: 1 Pages: 6-16
- DOI
  10.1016/j.micinf.2013.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791822, KAKENHI-PROJECT-24580133, KAKENHI-PROJECT-24659821, KAKENHI-PROJECT-24659924
[Journal Article] Effect of Porphyromonas gingivalis outer membrane vesicles on gingipain-mediated detachment of cultured oral epithelial cells and immune responses2014
- Author(s)
  Nakao R, Takashiba S, Kosono S, Yoshida M, Watanabe H, Ohnishi M, Senpuku H
- Journal Title
  
  Microbes and Infection
  
  Volume: 16(1) Pages: 6-16
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] A Novel Approach for Purification and Selective Capture of Membrane Vesicles of the Periodontopathic Bacterium, Porphyromonas gingivalis : Membrane Vesicles Bind to Magnetic Beads Coated with Epoxy Groups in a Noncovalent, Species-Specific Manner2014
- Author(s)
  Nakao R, Kikushima K, Higuchi H, Obana N, Nomura N, Bai D, Ohnishi M, Senpuku H
- Journal Title
  
  PLoS ONE
  
  Volume: 9(5)
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Enhanced biofilm formation of Escherichia coli LPS mutants defective in Hep biosynthesis2012
- Author(s)
  Ryoma Nakao
- Journal Title
  
  PLoS One
  
  Volume: 7(12) Issue: 12 Pages: e51241-e51241
- DOI
  10.1371/journal.pone.0051241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Enhanced biofilm formation of Escherichia coli LPS mutants defective in Hep biosynthesis2012
- Author(s)
  Nakao R, Ramstedt M, Wai SN, Uhlin BE
- Journal Title
  
  PLoS ONE
  
  Volume: 7(12)
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Outer membrane vesicles of Porphyromonas gingivalis elicit a mucosal immune response2011
- Author(s)
  Nakao R, Hasegawa H, Ochiai K, Takashiba S, Ainai A, Ohnishi M, Watanabe H, and Senpuku H
- Journal Title
  
  PloS ONE
  
  Volume: 6 Issue: 10 Pages: e26163-e26163
- DOI
  10.1371/journal.pone.0026163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390506, KAKENHI-PROJECT-22791822
[Journal Article] Outer Membrane Vesicles of Porphyromonas gingivalis Elicit a Mucosal Immune Response2011
- Author(s)
  Nakao R, Hasegawa H, Ochiai K, Takashiba S, Ainai A, Ohnishi M, Watanabe H, Senpuku H
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Monitoring surface chemistry changes in the bacterial cell wall - multivariate analysis of Cryo-X-ray photoelectron spectroscopy data2011
- Author(s)
  Ramstedt M, Nakao R, Wai SN, Uhlin BE, and Boily JF
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 12389-96
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Impact of minocycline ointment for periodontal treatment of oral bacteria2011
- Author(s)
  Nakao R, Takigawa S, Sugano N, Koshi R, Ito K, Watanabe H, Senpuku H.
- Journal Title
  
  Japanese Journal of Infectious Diseases
  
  Volume: 64 Pages: 156-160
- NAID
  40018775777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Monitoring surface chemical changes in the bacterial cell wall : multivariate analysis of cryo-x-ray photoelectron spectroscopy data2011
- Author(s)
  Ramstedt M, Nakao R, Wai SN, Uhlin BE, Boily JF
- Journal Title
  
  J Biol Chem
  
  Volume: 286(14) Issue: 14 Pages: 12389-12396
- DOI
  10.1074/jbc.m110.209536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Impact of minocycline ointment for periodontal treatment of oral bacteria2011
- Author(s)
  Nakao R, Takigawa S, Sugano N, Koshi R, Ito K, Watanabe H, Senpuku H
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 64(2) Pages: 156-160
- NAID
  40018775777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Monitoring surface chemistry changes in the bacterial cell wall-multivariate analysis of Cryo-X-ray photoelectron spectroscopy data2011
- Author(s)
  Ramstedt M, Nakao R, Wai SN, Uhlin BE, Boily JF
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 12389-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791822
[Journal Article] Inhibition of Streptococcus mutans adherence and biofilm formation using analogues of the SspB peptide2010
- Author(s)
  Okuda K, Hanada N, Usui Y, Takeuchi H, Koba H, Nakao R, Watanabe H, and Senpuku H
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 55 Pages: 754-762
- URL
  http://dx.doi.org/10.1016/j.archoralbio.2010.06.014
- Data Source
  KAKENHI-PROJECT-21390506
[Journal Article] Effects of Enterococcus faecium on Streptococcus mutans biofilm formati On using flow cell system2008
- Author(s)
  Kumada M., Senpuku H., Motegi M., Nakao R., Ybnezawa H., Yamamura H., Watanabe H., and Tagami J.
- Journal Title
  
  JounalofOralBiosciences 50
  
  Pages: 68-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791360
[Journal Article] Glycosylation of the OMP85 homolog of Porphyromonas gingivalis and its involvemet in biofilm fomation.2008
- Author(s)
  Nakao R, Tashiro Y, Nomura N, Kosono S, Ochiai K, Yonezawa E, watanabe H, Senpuku H.
- Journal Title
  
  Biochemical Biophysical Research Communications 365
  
  Pages: 784-789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791360
[Journal Article] Opr86is essential for viability and is a potential candidate for a protecfive antigen against biofilm formation by Pseudomonas aeruginosa2008
- Author(s)
  Tashiro Y, Nomura N, Nakao R Senpuku H, Kariyama R, Kumon H., Klosom S, Watanabe H, Nakajima T, Uchlyama H.
- Journal Title
  
  Jounal of Bacteriology 190(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791360
[Journal Article] Relationships of anti-PAc (361-386) peptide salivary IgA antibody, eosinophils and basophils with periodontal status in the elderly2007
- Author(s)
  Hidenobu Senpuku, Akio Tada, Ryoma Nakao, Hideo Yonezawa, Saori Yoneda, Akihiro Yoshihara A, Hideo Miyazaki
- Journal Title
  
  FEMS Immunology and Medical Microbiology 49(1)
  
  Pages: 84-90
- Data Source
  KAKENHI-PROJECT-17791348
[Journal Article] Human T cell responses to oral streptococci in human PBMC-NOD/SCID mice2006
- Author(s)
  Salam MA, Nakao R, Yonezawa H, Watanabe H, Senpuku H
- Journal Title
  
  Oral Microbiology and Immunology 21
  
  Pages: 169-176
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390571
[Journal Article] Human T cell responses to oral streptococci in human PBMC-NOD/SCID mice2006
- Author(s)
  Salam MA, Nakao R, Yonezawa H, Watanabe H, Senpuku H
- Journal Title
  
  Oral Microbiology and Immunology 21・3
  
  Pages: 169-176
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390571
[Journal Article] Porphyromonas gingivalis galE is involved in lipopolysaccharide O-antigen synthesis and biofilm formation2006
- Author(s)
  Ryoma Nakao, Hidenobu Senpuku, Haruo Watanabe
- Journal Title
  
  Infection and Immunity 74(11)
  
  Pages: 6145-6153
- Data Source
  KAKENHI-PROJECT-17791348
[Journal Article] Assessment of oral transmission using cell-free HIV -1 in mice reconstituted with human peripheral blood leukocyte.2003
- Author(s)
  R.Nakao, H.Senpuku et al.
- Journal Title
  
  Immunology 109
  
  Pages: 271-282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390571
[Journal Article] Assessment of oral transmission using cell-free HIV-1 in mice reconstituted with human peripheral blood leukocyte.2003
- Author(s)
  R.Nakao, H.Senpuku et al.
- Journal Title
  
  Immunology 109
  
  Pages: 271-282
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390571
[Journal Article] Human T cell responses to oral streptococci in human PBMC-NOD/SCID mice
- Author(s)
  Salam MA, Nakao R, Yonezawa H, Watanabe H, Senpuku H
- Journal Title
  
  Oral Microbiology and Immunology (in press)
- Data Source
  KAKENHI-PROJECT-15390571
[Patent] プロバイオティクス大腸菌の二重変異株、該二重変異株から産生される膜小胞、及びそれを用いた製品2024
- Inventor(s)
  中尾龍馬、安部公博、尾花望、渡辺賢二
- Industrial Property Rights Holder
  国立感染症研究所長
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-033964
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-20H03861
[Patent] プロバイオティクス大腸菌の二重変異株、該二重変異株から産生される膜小胞、及びそれを用いた製品2024
- Inventor(s)
  中尾龍馬、安部公博、尾花望、渡辺賢二
- Industrial Property Rights Holder
  国立感染症研究所長
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-033964
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21KK0164
[Patent] バチルス属細菌の膜小胞を基盤とする担体及びそれを用いた製品2024
- Inventor(s)
  安部公博、中尾龍馬
- Industrial Property Rights Holder
  国立感染症研究所長
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-037222
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-20H03861
[Patent] バチルス属細菌の膜小胞を基盤とする担体及びそれを用いた製品2024
- Inventor(s)
  安部公博、中尾龍馬
- Industrial Property Rights Holder
  国立感染症研究所長
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-037222
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21K18284
[Patent] バチルス属細菌の膜小胞を基盤とする担体及びそれを用いた製品2024
- Inventor(s)
  安部公博、中尾龍馬
- Industrial Property Rights Holder
  国立感染症研究所長
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-037222
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21KK0164
[Patent] プロバイオティクス大腸菌の二重変異株、該二重変異株から産生される膜小胞、及びそれを用いた製品2024
- Inventor(s)
  中尾龍馬、安部公博、尾花望、渡辺賢二
- Industrial Property Rights Holder
  国立感染症研究所長
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-033964
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21K18284
[Patent] ポルフィロモナス・ジンジバリス用殺菌剤、及びポルフィロモナス・ジンジバリスに対する抗菌作用を有する成分を製造する方法2021
- Inventor(s)
  吉野七海、池田剛、中尾龍馬
- Industrial Property Rights Holder
  エスビー食品
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-057781
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K18284
[Patent] ポルフィロモナス・ジンジバリス用殺菌剤、及びポルフィロモナス・ジンジバリスに対する抗菌作用を有する成分を製造する方法2021
- Inventor(s)
  吉野七海、池田剛、中尾龍馬
- Industrial Property Rights Holder
  エスビー食品
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-057781
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21KK0164
[Patent] メンブレンヴェシクル2019
- Inventor(s)
  中尾龍馬、庄子幹郎、中山浩次
- Industrial Property Rights Holder
  公益財団法人ヒューマンサイエンス振興財団
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-080136
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K22644
[Patent] Methods of inspecting periodontal disease causing bacteria using outer membrane vesicle2013
- Inventor(s)
  Ryoma Nakao, Hidenobu Senpuku, Makoto Ohnishi, Kazuto Takayama, Hiroki Naito, Tetsuo Sakuma
- Industrial Property Rights Holder
  GC corp. and Natl. Inst. Infect. Dis
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-07
- Overseas
- Data Source
  KAKENHI-PROJECT-22791822
[Patent] Methods of inspecting periodontal disease causing bacteria using outer membrane vesicle2013
- Inventor(s)
  Ryoma Nakao, Hidenobu Senpuku, Makoto Ohnishi, Kazuto Takayama, Hiroki Naito, Tetsuo Sakuma
- Industrial Property Rights Holder
  GC corp. and Natl. Inst. Infect. Dis
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-08
- Overseas
- Data Source
  KAKENHI-PROJECT-22791822
[Patent] Method of inspecting periodontal disease causing bacteria using outer membrane vesicle and measuring appliance of the same2013
- Inventor(s)
  中尾龍馬、泉福英信、大西真、高山和人、内藤裕樹、佐久間徹郎
- Industrial Property Rights Holder
  株式会社ジーシー、国立感染症研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-08
- Overseas
- Data Source
  KAKENHI-PROJECT-22791822
[Patent] 外膜ヴェシクルを用いた歯周病原細菌の検査方法及び測定用器具2012
- Inventor(s)
  中尾龍馬、泉福英信、大西真、高山和人、内藤裕樹、佐久間徹郎
- Industrial Property Rights Holder
  株式会社GCおよび国立感染症研究所
- Industrial Property Number
  2012-049148
- Filing Date
  2012-03-06
- Data Source
  KAKENHI-PROJECT-22791822
[Patent] 外膜ヴェシクルを用いた歯周病原細菌の検査方法2012
- Inventor(s)
  中尾龍馬, 泉福英信, 大西真, 高山和人, 内藤裕樹, 佐久間徹郎
- Industrial Property Rights Holder
  株式会社GC,国立感染症研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2012-03-06
- Data Source
  KAKENHI-PROJECT-22791822
[Patent] 特許「緑膿菌バイオフィルム形成に対するワクチン抗原体」2007
- Inventor(s)
  野村暢彦、田代陽介、内山裕夫、泉福英信、中尾龍馬
- Industrial Property Number
  2007-247263
- Filing Date
  2007-09-25
- Data Source
  KAKENHI-PROJECT-19791360
[Presentation] 細菌が創る膜小胞ワクチン：歯周病や感染症の制御に向けた取り組み2024
- Author(s)
  中尾龍馬
- Organizer
  日本小動物歯科研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] A Novel Vaccine Platform against Pneumococcal Infection Using Glycoengineered Membrane Vesicles of Probiotic Escherichia coli2024
- Author(s)
  Ryoma Nakao
- Organizer
  The 4th Asian Pneumococcal Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] 細菌が創る膜小胞ワクチン：歯周病や感染症の制御に向けた取り組み2024
- Author(s)
  中尾龍馬
- Organizer
  日本小動物歯科研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] 細菌が創る膜小胞ワクチン：歯周病や感染症の制御に向けた取り組み2024
- Author(s)
  中尾龍馬
- Organizer
  日本小動物歯科研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 大腸菌膜小胞のワクチン利用に向けた異種多糖抗原輸送効率の向上2023
- Author(s)
  竹井奎多、今泉昌慶、二又裕之、中尾龍馬、田代陽介
- Organizer
  日本膜学会第45年会,膜シンポジウム2023の合同大会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Mahanimbineは歯周病原細菌の表面にクレーター状の穴を開ける2023
- Author(s)
  中尾龍馬、池田剛、明田幸宏
- Organizer
  第96回日本生化学会総会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] 生物発光共鳴エネルギー移動を用いた細菌膜小胞の生体内観察最適化2023
- Author(s)
  木本万結、小根山千歳、二又裕之、中尾龍馬、田代陽介
- Organizer
  第36回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] 生物発光共鳴エネルギー移動を用いた細菌膜小胞の生体内観察最適化2023
- Author(s)
  木本万結、小根山千歳、二又裕之、中尾龍馬、田代陽介
- Organizer
  第36回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] プロバイオティクス大腸菌由来外膜小胞を使った肺炎球菌ワクチンの投与ルートとの検討2023
- Author(s)
  中尾龍馬、安倍公博、山口雄大、木村聡一郎、明田幸宏
- Organizer
  第53回レンサ球菌研究会
- Data Source
  KAKENHI-PROJECT-22K08609
[Presentation] 膜小胞ワクチン：歯周病や感染症の制御に向けた取組み2023
- Author(s)
  中尾龍馬
- Organizer
  第106回日本細菌学会関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Fate of Porphyromonas ginigivalis outer membrane vesicles intravesously administered to mice2023
- Author(s)
  内山大樹、山口雄大、宮崎英隆、明田宏幸、中尾龍馬
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 膜小胞ワクチン：歯周病や感染症の制御に向けた取組み2023
- Author(s)
  中尾龍馬
- Organizer
  第106回日本細菌学会関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 鼻粘膜投与型の細菌由来膜小胞ワクチン2023
- Author(s)
  中尾龍馬
- Organizer
  第57回緑膿菌感染症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] A Novel Vaccine Platform against Pneumococcal Infection Using Glycoengineered Membrane Vesicles of Probiotic Escherichia coli2023
- Author(s)
  Ryoma Nakao
- Organizer
  The 4th Asian Pneumococcal Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 大腸菌膜小胞のワクチン利用に向けた異種多糖抗原輸送効率の向上2023
- Author(s)
  竹井奎多、今泉昌慶、二又裕之、中尾龍馬、田代陽介
- Organizer
  日本膜学会第45年会,膜シンポジウム2023の合同大会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] フェンネルシード由来ペトロセリン酸による口腔環境改善の可能性2023
- Author(s)
  吉野七海、小池麻里子、伊藤建吾、恩田浩幸、池田　剛、中尾龍馬
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20K07122
[Presentation] 歯周病原細菌とその外膜小胞の構成・構造の解析2023
- Author(s)
  高橋葵、長田勝英、中村知世、西野智彦、小林宏尚、中尾龍馬
- Organizer
  第96回日本生化学会総会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 生体内イメージングに向けた長波長発光膜小胞の作製2023
- Author(s)
  木本万結、小根山千歳、中尾龍馬、二又裕之、田代陽介
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 大腸菌膜小胞のワクチン利用に向けた異種多糖抗原輸送効率の向上2023
- Author(s)
  竹井奎多、今泉昌慶、二又裕之、中尾龍馬、田代陽介
- Organizer
  日本膜学会第45年会,膜シンポジウム2023の合同大会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] Mahanimbineは歯周病原細菌の表面にクレーター状の穴を開ける2023
- Author(s)
  中尾龍馬、池田剛、明田幸宏
- Organizer
  第96回日本生化学会
- Data Source
  KAKENHI-PROJECT-20K07122
[Presentation] 生体内イメージングに向けた長波長発光膜小胞の作製2023
- Author(s)
  木本万結、小根山千歳、中尾龍馬、二又裕之、田代陽介
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Mahanimbineは歯周病原細菌の表面にクレーター状の穴を開ける2023
- Author(s)
  中尾龍馬、池田剛、明田幸宏
- Organizer
  第96回日本生化学会総会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] 歯周病原細菌とその外膜小胞の構成・構造の解析2023
- Author(s)
  高橋葵、長田勝英、中村知世、西野智彦、小林宏尚、中尾龍馬
- Organizer
  第96回日本生化学会総会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] ウシ型結核菌弱毒株BCG由来メンブレンヴェシクルを用いた新規結核ワクチン開発2023
- Author(s)
  山口雄大、寒川訓明、中尾龍馬、明田幸宏
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Mahanimbineは歯周病原細菌の表面にクレーター状の穴を開ける2023
- Author(s)
  中尾龍馬、池田剛、明田幸宏
- Organizer
  第96回日本生化学会総会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Fate of Porphyromonas ginigivalis outer membrane vesicles intravesously administered to mice2023
- Author(s)
  内山大樹、山口雄大、宮崎英隆、明田宏幸、中尾龍馬
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] ウシ型結核菌弱毒株BCG由来メンブレンヴェシクルを用いた新規結核ワクチン開発2023
- Author(s)
  山口雄大、寒川訓明、中尾龍馬、明田幸宏
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] 鼻粘膜投与型の細菌由来膜小胞ワクチン2023
- Author(s)
  中尾龍馬
- Organizer
  第57回緑膿菌感染症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] プロバイオティクス大腸菌キメラ由来メンブレンヴェシクルによる莢膜保有病原体に対するワクチン2023
- Author(s)
  中尾龍馬、岩渕佑介、川原一芳、明田幸宏、大西真
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 生物発光共鳴エネルギー移動を用いた細菌膜小胞の生体内観察最適化2023
- Author(s)
  木本万結、小根山千歳、二又裕之、中尾龍馬、田代陽介
- Organizer
  第36回日本微生物生態学会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] フェンネルシード由来ペトロセリン酸による口腔環境改善の可能性2023
- Author(s)
  吉野七海、小池麻里子、伊藤健吾、恩田浩之、池田剛、中尾龍馬
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] 膜小胞ワクチン：歯周病や感染症の制御に向けた取組み2023
- Author(s)
  中尾龍馬
- Organizer
  第106回日本細菌学会関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] A Novel Vaccine Platform against Pneumococcal Infection Using Glycoengineered Membrane Vesicles of Probiotic Escherichia coli2023
- Author(s)
  Ryoma Nakao
- Organizer
  The 4th Asian Pneumococcal Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] プロバイオティクス大腸菌由来外膜小胞を使った肺炎球菌ワクチンの投与ルートの検討2023
- Author(s)
  中尾龍馬、安部公博、山口雄大、木村聡一郎、明田幸宏
- Organizer
  第 53 回レンサ球菌研究会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] 歯周病原細菌とその外膜小胞の構成・構造の解析2023
- Author(s)
  高橋葵、長田勝英、中村知世、西野智彦、小林宏尚、中尾龍馬
- Organizer
  第96回日本生化学会総会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] プロバイオティクス大腸菌キメラ由来メンブレンヴェシクルによる莢膜保有病原体に対するワクチン2023
- Author(s)
  中尾龍馬、岩渕佑介、川原一芳、明田幸宏、大西真
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] 百日咳菌の外膜小胞を用いた経鼻ワクチンによる抗体応答評価2023
- Author(s)
  石川青空、相内　章、小林万倫、坂本玲奈、中尾龍馬、田村浩二、鈴木忠樹
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K08596
[Presentation] マウスにおけるPorphyromonas gingivalis 由来外膜小胞の血行動態について2022
- Author(s)
  内山大樹、宮崎英隆、山口雄大、中尾龍馬
- Organizer
  第64回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] ポルフィロモナス・ジンジバリスに対するフェンネルの二重阻害活性2022
- Author(s)
  吉野七海、池田剛、中尾龍馬
- Organizer
  第36回日本香辛料研究会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] 細菌由来メンブレンヴェシクルの医療応用に向けた取組み2022
- Author(s)
  中尾龍馬
- Organizer
  第29回内毒素・LPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] BCG 由来細胞外小胞の新規結核ワクチンへの応用2022
- Author(s)
  山口雄大、寒川訓明、中尾龍馬、明田幸宏
- Organizer
  第26回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] BCG 由来細胞外小胞の新規結核ワクチンへの応用2022
- Author(s)
  山口雄大、寒川訓明、中尾龍馬、明田幸宏
- Organizer
  第26回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] 歯周病ワクチンの研究:細菌由来外膜小胞による優れた粘膜免疫原性の活用2022
- Author(s)
  中尾龍馬、山口雄大、石原和幸、明田幸宏
- Organizer
  第26回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] ポルフィロモナス・ジンジバリスに対するフェンネルの二重阻害活性2022
- Author(s)
  吉野七海、池田剛、中尾龍馬
- Organizer
  第36回　日本香辛料研究会
- Data Source
  KAKENHI-PROJECT-20K07122
[Presentation] 細菌由来メンブレンヴェシクルの医療応用に向けた取組み2022
- Author(s)
  中尾龍馬
- Organizer
  第29回内毒素・LPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] 細菌が放出する膜小胞の免疫誘導とワクチンへの応用2022
- Author(s)
  竹井奎多、高原翠夏人、今泉昌慶、二又裕之、中尾龍馬、田代陽介
- Organizer
  大腸菌研究会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] ポルフィロモナス・ジンジバリスに対するフェンネルの二重阻害活性2022
- Author(s)
  吉野七海、池田剛、中尾龍馬
- Organizer
  第36回日本香辛料研究会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 細菌が放出する膜小胞の免疫誘導とワクチンへの応用2022
- Author(s)
  竹井奎多、高原翠夏人、今泉昌慶、二又裕之、中尾龍馬、田代陽介
- Organizer
  大腸菌研究会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] マウスにおけるPorphyromonas gingivalis 由来外膜小胞の血行動態について2022
- Author(s)
  内山大樹、宮崎英隆、山口雄大、中尾龍馬
- Organizer
  第64回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 細菌が放出する膜小胞の免疫誘導とワクチンへの応用2022
- Author(s)
  竹井奎多、高原翠夏人、今泉昌慶、二又裕之、中尾龍馬、田代陽介
- Organizer
  大腸菌研究会
- Data Source
  KAKENHI-PROJECT-19H02920
[Presentation] 歯周病ワクチンの研究:細菌由来外膜小胞による優れた粘膜免疫原性の活用2022
- Author(s)
  中尾龍馬、山口雄大、石原和幸、明田幸宏
- Organizer
  第26回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] グリシンにより誘導された細菌メンブレンベシクルの性質とアジュバント活性の解析2021
- Author(s)
  平山悟、中尾龍馬
- Organizer
  第63回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] ウェルシュ菌が放出するメンブレンベシクルを介した宿主免疫誘導の解析2021
- Author(s)
  奥田真由，尾花望，奥脇響，中尾龍馬，泉福英信，野村暢彦
- Organizer
  第94回日本細菌学会
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Study on glucosyltransferase of Streptococcus mutans2021
- Author(s)
  Tomoyo Nakamura, Naoki Narisawa, Fumio Takenaga, Ryoma Nakao, and Hidenobu Senpuku
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] Intranasal vaccine development using probiotic E. coli-derived membrane vesicles carrying pneumococcal capsular polysaccharides2021
- Author(s)
  Nakao R, Iwabuchi Y, Kimura S, Hirayama S, Morino S, Suzuki M, Ohnishi M.
- Organizer
  15th Vaccine Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] 細菌由来メンブレンヴェシクル:その優れた特性を活用したワクチン開発2021
- Author(s)
  中尾龍馬
- Organizer
  第94回日本細菌学会
- Data Source
  KAKENHI-PROJECT-20K09943
[Presentation] Dual inhibitory effects of fennel seeds against Porphyromonas gingivalis2021
- Author(s)
  Nanami Yoshino、Tsuyoshi Ikeda、Ryoma Nakao
- Organizer
  World Microbe Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07122
[Presentation] Prospective vaccine strategy using bacterial membrane vesicles delivered into nasal cavity2021
- Author(s)
  Ryoma Nakao
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Effect of initial pH conditions on the membrane vesicles produced by Streptococcus mutans2021
- Author(s)
  Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Development of anti-TB vaccine using mycobacterial membrane vesicles2021
- Author(s)
  Takehiro Yamaguchi, Noriaki Samukawa, Ryoma Nakao and Shuhei Tomita
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] Study on glucosyltransferase of Streptococcus mutans2021
- Author(s)
  Tomoyo Nakamura, Naoki Narisawa, Fumio Takenaga, Ryoma Nakao, and Hidenobu Senpuku
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Effect of initial pH conditions on the membrane vesicles produced by Streptococcus mutans2021
- Author(s)
  Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] BCG 由来メンブレンヴェシクルを用いた結核ワクチン開発研究2021
- Author(s)
  山口雄大，中尾龍馬，冨田修平
- Organizer
  第94回日本細菌学会
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Intranasal vaccine development using probiotic E. coli-derived membrane vesicles carrying pneumococcal capsular polysaccharides2021
- Author(s)
  Nakao R, Iwabuchi Y, Kimura S, Hirayama S, Morino S, Suzuki M, Ohnishi M.
- Organizer
  15th Vaccine Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] グリシンにより誘導された細菌メンブレンベシクルの性質とアジュバント活性の解析2021
- Author(s)
  平山悟、中尾龍馬
- Organizer
  第63回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 腸内細菌由来メンブレンベシクルによる宿主免疫を介した宿主微生物叢制御2021
- Author(s)
  奥田真由、尾花望、奥脇響、中尾龍馬、泉福英信、野村暢彦
- Organizer
  第34回微生物生態学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 腸内細菌由来メンブレンベシクルによる宿主免疫を介した宿主微生物叢制御2021
- Author(s)
  奥田真由、尾花望、奥脇響、中尾龍馬、泉福英信、野村暢彦
- Organizer
  第34回微生物生態学会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] Effects of mucosal immunization of Clostridium perfringens membrane vesicles on humoral immunity and gut microbiota2021
- Author(s)
  Okuda Mayu, Obana Nozomu, Okuwaki Hibiki, Nakao Ryoma, Senpuku Hidenobu, Nomura Nobuhiko
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] Development of anti-TB vaccine using mycobacterial membrane vesicles2021
- Author(s)
  Takehiro Yamaguchi, Noriaki Samukawa, Ryoma Nakao and Shuhei Tomita
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Characterization of immunomodulatory membrane vesicles derived from Pseudomonas aeruginosa biofilm2021
- Author(s)
  者名 Minato Takahara, Satoru Hirayama, Ryoma Nakao, Hiroyuki Futamata, Yosuke Tashiro
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Study on glucosyltransferase of Streptococcus mutans2021
- Author(s)
  Tomoyo Nakamura, Naoki Narisawa, Fumio Takenaga, Ryoma Nakao, and Hidenobu Senpuku
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Characterization of immunomodulatory membrane vesicles derived from Pseudomonas aeruginosa biofilm2021
- Author(s)
  Minato Takahara, Satoru Hirayama, Ryoma Nakao, Hiroyuki Futamata, Yosuke Tashiro
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] グリシンにより誘導された細菌メンブレンベシクルの性質とアジュバント活性の解析2021
- Author(s)
  Hirayama S, Nakao R.
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-20K09943
[Presentation] Prospective vaccine strategy using bacterial membrane vesicles delivered into nasal cavity2021
- Author(s)
  Ryoma Nakao
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09943
[Presentation] 外来性莢膜多糖を発現するプロバイオティクス大腸菌が作る膜小胞ワクチンの特性評価2021
- Author(s)
  Ryoma Nakao, Hiroaki Kobayashi, Yusuke Iwabuchi, Yusuke Sasaki, Madeleine Ramstedt, Satoru Hirayama, Makoto Ohnishi
- Organizer
  第15回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Prospective vaccine strategy using bacterial membrane vesicles delivered into nasal cavity2021
- Author(s)
  Ryoma Nakao
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] Intranasal vaccine development using probiotic E. coli-derived membrane vesicles carrying pneumococcal capsular polysaccharides2021
- Author(s)
  Nakao R, Iwabuchi Y, Kimura S, Hirayama S, Morino S, Suzuki M, Ohnishi M.
- Organizer
  15th Vaccine Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Effect of initial pH conditions on the membrane vesicles produced by Streptococcus mutans2021
- Author(s)
  Yusuke Iwabuchi, Tomoyo Nakamura, Yasuka Kusumoto, Ryoma Nakao, Tsutomu Iwamoto, Osamu Shinozuka, Hidenobu Senpuku
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] P. gingivalis の膜小胞産生誘導及び迅速な殺菌効果を示すフェンネル抽出物2021
- Author(s)
  吉野七海、池田剛、中尾龍馬
- Organizer
  第94回日本細菌学会
- Data Source
  KAKENHI-PROJECT-20K09943
[Presentation] 外来性莢膜多糖を発現するプロバイオティクス大腸菌が作る膜小胞ワクチンの特性評価2021
- Author(s)
  Ryoma Nakao, Hiroaki Kobayashi, Yusuke Iwabuchi, Yusuke Sasaki, Madeleine Ramstedt, Satoru Hirayama, Makoto Ohnishi
- Organizer
  第15回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] Prospective vaccine strategy using bacterial membrane vesicles delivered into nasal cavity2021
- Author(s)
  Ryoma Nakao
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Development of anti-TB vaccine using mycobacterial membrane vesicles2021
- Author(s)
  Takehiro Yamaguchi, Noriaki Samukawa, Ryoma Nakao and Shuhei Tomita
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Inhibitory activity of mahanimbine against Porphyromonas gingivalis2021
- Author(s)
  Ryoma Nakao, Tsuyoshi Ikeda
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] 細菌由来メンブレンヴェシクル:その優れた特性を活用したワクチン開発2021
- Author(s)
  中尾龍馬
- Organizer
  第94回日本細菌学会
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Porphyromonas gingivalisに対するmahanimbineの阻害活性2021
- Author(s)
  中尾龍馬、池田　剛
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07122
[Presentation] Characterization of immunomodulatory membrane vesicles derived from Pseudomonas aeruginosa biofilm2021
- Author(s)
  Minato Takahara, Satoru Hirayama, Ryoma Nakao, Hiroyuki Futamata, Yosuke Tashiro
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] P. gingivalis の膜小胞産生誘導及び迅速な殺菌効果を示すフェンネル抽出物2021
- Author(s)
  吉野七海、中尾龍馬
- Organizer
  第94回日本細菌学会
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Effects of mucosal immunization of Clostridium perfringens membrane vesicles on humoral immunity and gut microbiota2021
- Author(s)
  Okuda Mayu, Obana Nozomu, Okuwaki Hibiki, Nakao Ryoma, Senpuku Hidenobu, Nomura Nobuhiko
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0164
[Presentation] Inhibitory activity of mahanimbine against Porphyromonas gingivalis2021
- Author(s)
  Ryoma Nakao, Tsuyoshi Ikeda
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Prospective vaccine strategy using bacterial membrane vesicles delivered into nasal cavity2021
- Author(s)
  Ryoma Nakao
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] Development of anti-TB vaccine using mycobacterial membrane vesicles2021
- Author(s)
  Takehiro Yamaguchi, Noriaki Samukawa, Ryoma Nakao and Shuhei Tomita
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09943
[Presentation] Inhibitory activity of mahanimbine against Porphyromonas gingivalis2021
- Author(s)
  Ryoma Nakao, Tsuyoshi Ikeda
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03861
[Presentation] 外来性莢膜多糖を発現するプロバイオティクス大腸菌が作る膜小胞ワクチンの特性評価2021
- Author(s)
  Ryoma Nakao, Hiroaki Kobayashi, Yusuke Iwabuchi, Yusuke Sasaki, Madeleine Ramstedt, Satoru Hirayama, Makoto Ohnishi
- Organizer
  第15回日本ワクチン学会
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Effects of mucosal immunization of Clostridium perfringens membrane vesicles on humoral immunity and gut microbiota2021
- Author(s)
  Okuda Mayu, Obana Nozomu, Okuwaki Hibiki, Nakao Ryoma, Senpuku Hidenobu, Nomura Nobuhiko
- Organizer
  EMBO Workshop: Bacterial Membrane Vesicles: Biogenesis, functions, and medical applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18284
[Presentation] グリシンにより誘導された細菌メンブレンベシクルの特性解析―歯周病細菌ベシクルワクチンの粘膜アジュバント開発等に向けて―2020
- Author(s)
  平山悟、中尾龍馬
- Organizer
  第62回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Probiotic Eshcherichia coli Membraned Vesicles Carrying Pneumococcal Capsular Polysaccharides: An In Vivo Study of intranasal Vaccines Using Safe and immunogenic Nanoparticles.2020
- Author(s)
  Ryoma Nakao, Satoru Hirayama, Iwabuchi Yusuke, Makoto Ohnishi
- Organizer
  12th International Symposium on Pneumococci & Pneumococcal Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] バイオフィルム由来膜小胞による免疫応答促進（学術奨励賞）2020
- Author(s)
  高原翠夏人、平山悟、中尾龍馬、二又裕之、田代陽介
- Organizer
  2020年度日本農芸化学会中部支部
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] 粘膜免疫を強く誘導する細菌由来メンブレンヴェシクル2020
- Author(s)
  中尾龍馬
- Organizer
  NIID/futureセミナー「ワクチン開発研究の現状と展望」
- Invited
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] バイオフィルム由来膜小胞による免疫応答促進2020
- Author(s)
  髙原翠夏人、平山悟、中尾龍馬、二又裕之、田代陽介
- Organizer
  日本農芸化学会中部支部大会
- Data Source
  KAKENHI-PROJECT-19H02920
[Presentation] グリシンによる細菌メンブレンベシクル産生の誘導とその特性2020
- Author(s)
  平山悟、中尾龍馬
- Organizer
  生物工学会Webシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K22644
[Presentation] Effects of membrane vesicles from Streptococcus mutans on the biofilm formation and mucosal immunity.2018
- Author(s)
  Senpuku Hidenobu, Tominaga Akira, Nakao Ryoma
- Organizer
  96th General Session & Exhibition of the International Association for Dental Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11537
[Presentation] 膜小胞-細胞外DNA複合体の病原性と粘膜免疫によるIgA抗体の誘導2018
- Author(s)
  泉福英信, 中尾龍馬
- Organizer
  第60回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-16K11537
[Presentation] Streptococcus mutansからのメンブレンヴェジクルによる口腔細菌バイオフィルムの確立2017
- Author(s)
  泉福英信、中尾龍馬、大西真
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K11537
[Presentation] Vaccine Efficacy and Safety of Outer Membrane Vesicles Derived from a Major Periodontopathic Bacterium, Porphyromonas gingivalis2017
- Author(s)
  Ryoma Nakao
- Organizer
  Joint Meeting of Umea Univ and Karolinska Institutet
- Place of Presentation
  スウェーデン　ウメオ
- Year and Date
  2017-03-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Mucosal adjuvanticity of Aggregatibacter actinomycetemcomitans outer membrane vesicles2017
- Author(s)
  Satoru Hirayama, Hidenobu Senpuku, Makoto Ohnishi, Ryoma Nakao
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Propolis immediately triggers bactericidal action through the aberrant bleb formation and membrane perturbation at the bacterial surface2017
- Author(s)
  Yuri Yoshimasu, Tsuyoshi Ikeda, Akira Yagi, Yasushi Morinaga, Souichi Furukawa, Ryoma Nakao,
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Assessment of outer membrane vesicle of Porphyromonas gingivalis as a mucosal immunogen candidate for development of a periodontal disease vaccine2016
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  10th Vaccine Congress
- Place of Presentation
  オランダ　アムステルダム
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Assessment of outer membrane vesicle of Porphyromonas gingivalis as a mucosal immunogen candidate for development of a periodontal disease vaccine2016
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Yuri Yoshimasu, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  ASM Conference on antibacterial development
- Place of Presentation
  アメリカ　ワシントンDC
- Year and Date
  2016-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Membrane vesicels of Clostridium perfringens induce host immune response2016
- Author(s)
  永山恭子、尾花望、中尾龍馬、泉福英信、中村幸治、野村暢彦
- Organizer
  日本農芸化学会2016
- Place of Presentation
  札幌
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Therapeutic implications of propolis and curry leaf against periodontitis2016
- Author(s)
  Ryoma Nakao, Y. Ogata, T Shimizu, H. Senpuku.
- Organizer
  94th General Session of International association for Dental Research
- Place of Presentation
  韓国　ソウル
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] 殺菌性を有する食品を利用した歯周病原細菌の制御に関する研究2016
- Author(s)
  Ryoma Nakao
- Organizer
  第58回歯科基礎医学会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] A feasible intranasal vaccine strategy using bacterial outer membrane vesicles: ―the safety and cross-protective immunity―2016
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  Keystone Symposia, Translational vaccinology for global health
- Place of Presentation
  イギリス　ロンドン
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] A feasible intranasal vaccine strategy using bacterial outer membrane vesicles (OMVs) ―the safety and cross-protective immunity―2016
- Author(s)
  Ryoma Nakao
- Organizer
  Seminar at Karolinska Insitutet
- Place of Presentation
  スウェーデン　ストックホルム
- Year and Date
  2016-08-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Immunoactive membrane vesicles are actively produced by the Gram-positive clostridial pathogen2016
- Author(s)
  尾花望、中尾龍馬、永山恭子、泉福英信、野村暢彦
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Porphyromonas gingivalisの外膜ヴェシクル-歯周病粘膜ワクチンの候補抗原としての評価-2016
- Author(s)
  中尾龍馬、大西真、泉福英信
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Functional analysis of membrane vesicles released by intestinal bacteria2016
- Author(s)
  Kyoko Nagayama1, Nozomu Obana1, Ryoma Nakao2, Hidenobu Senpuku2, Kouji Nakamura1, Nobuhiko Nomura1
- Organizer
  Interdisciplinary Workshop on Science and Patents (IWP)2016
- Place of Presentation
  筑波
- Year and Date
  2016-09-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Clostridium perfringensのメンブランベシクルを介した宿主免疫誘導2016
- Author(s)
  永山恭子1、尾花望1、中尾龍馬2、泉福英信2、中村幸治1、野村暢彦1
- Organizer
  グラム陽性菌ゲノム機能会議
- Place of Presentation
  熱海
- Year and Date
  2016-08-29
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] 歯周病細菌由来ヴェシクルの経鼻粘膜ワクチンへの応用2016
- Author(s)
  Ryoma Nakao
- Organizer
  第30回日本バイオフィルム学会学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] 歯周病関連菌のLPSとその特徴2015
- Author(s)
  泉福英信、中尾龍馬
- Organizer
  第５８回春季日本歯周病学会学術大会
- Place of Presentation
  東京
- Year and Date
  2015-05-14
- Invited
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] ウェルシュ菌のメンブランベシクルを介した宿主免疫誘導2015
- Author(s)
  永山恭子、尾花望、中尾龍馬、泉福英信、中村幸治、野村暢彦
- Organizer
  第30回日本微生物生態学会2015
- Place of Presentation
  土浦
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Assessment of immune responses in mice after intranasal immunization using outer membrane vesicles derive from 3 different Gram-negative pathogens2015
- Author(s)
  Ryoma Nakao, Nozomu Obana, Kyoko Nagayama, Nobuhiko Nomura, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  International Congress of Mucosal Immunolgy
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-07-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Porphyromonas gingivalis外膜ヴェシクルは２型免疫応答を誘導する2015
- Author(s)
  中尾龍馬、泉福英信
- Organizer
  第57回歯科基礎医学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] X-ray photoelectron spectroscopy of intact bacterial cells can help evaluate changes in cell wall composition with respect to lipid, sugar and peptide containing compounds.2013
- Author(s)
  Madeleine Ramstedt, Ryoma Nakao, Laura Leone, Andrey Shchukarev, Per Persson, , Jean-Francois Boily, Sun Nyunt Wai, Bernt Eric Uhlin
- Organizer
  Nobel Conference on Biofilm formation, its clinical impact and potential treatment
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Immunoreactive antigens recognized by sera of mice intranasally immunized with outer membrane vesicles of Porphyromonas gingivalis2013
- Author(s)
  Dongyin Bai, Ryoma Nakao, Hidenobu Senpuku
- Organizer
  British Society for Immunology BSI 2013
- Place of Presentation
  Liverpool, UK
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Ig responses in mice after intranasal immunization of Porphyromonas gingivalis outer membrane vesicles2013
- Author(s)
  中尾龍馬
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉県幕張市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Effect of Porphyomonas gingivalis outer membrane vesicles on gingipain-mediated detachment of cultured oral epithelial cells and immune responses.2013
- Author(s)
  Nakao R, Takashiba S, Kosono S, Yoshida M, Watanabe H, Ohnishi M, Senpuku H.
- Organizer
  British Society for Immunology BSI 2013
- Place of Presentation
  Liverpool, UK
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Enhanced biofilm formationby Escherichia coli carrying a commonly occurring plasmid gene, "kil"2013
- Author(s)
  Ryoma Nakao, Sun Nyunt Wai, and Bernt Eric Uhlin
- Organizer
  Nobel Conference on Biofilm formation, its clinical impact and potential treatment
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Role of Outer Membrane Vesicles of Porphyromonas gingivalis in Immunopathology of Periodontitis in Human.2012
- Author(s)
  Ryoma Nakao
- Organizer
  第34回内藤カンファレンス感染・炎症・免疫
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Humoral immunity against Porphyromonas gingivalis in mice intranasally vaccinated with combination of outer membrane vesicles and synthetic2012
- Author(s)
  中尾龍馬
- Organizer
  第16回日本ワクチン学会学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Roles of outer vesicles of Porphyromonas gingivalis for a mucosalimmune response2012
- Author(s)
  H Senpuku and R Nakao
- Organizer
  First International Conference on Porphyromonas gingivalis
- Place of Presentation
  長崎
- Invited
- Data Source
  KAKENHI-PROJECT-24659821
[Presentation] Outer membrane vesicles of P. gingivalis carry a variety of antigens and virulence factors.2012
- Author(s)
  中尾龍馬
- Organizer
  第54回歯科基礎医学会学術集会・総会
- Place of Presentation
  福岡県郡山市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Roles of outer membrane vesicles of Porphyromonas gingivalis for a mucosal immune response2012
- Author(s)
  Ryoma Nakao
- Organizer
  First International Conference on Porphyromonas gingivalis and Related Bacterial Species
- Place of Presentation
  長崎県長崎市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Dose-dependent effect of the kil gene on biofilm formation of E.coli2011
- Author(s)
  Ryoma Nakao, Madeleine Ramstedt, Sun Nyunt Wai, Bernt Eric Uhlin
- Organizer
  Eurobiofilms 2011
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Immunological properties of outer membrane vesicles from Porphyromon as gingivalis2011
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Akira Ainai, Haruo Watanabe, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo, JPN
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Immunological properties of outer membrane vesicles from Porphyromon as gingivalis2011
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Akira Ainai, Makoto Ohnishi, Haruo Watanabe, Hidenobu Senpuku
- Organizer
  5th National Infection Biology Meeting
- Place of Presentation
  Umea, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] I.Effect of deletion of LPS core oligosaccharides on Biofilm formation and OMV formulation. II. Immunological Properties of Outer Membrane Vesicles from Porphyromonas gingivalis2011
- Author(s)
  Ryoma Nakao
- Organizer
  1st Cell Adhesion Workshop
- Place of Presentation
  Umea, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Monitoring bacterial cell wall composition using cryo-XPS and multivariate analysis2011
- Author(s)
  Madeleine Ramstedt, Ryoma Nakao, Sun Nyunt Wai, Bernt Eric Uhlin, Jean-Francois Boily
- Organizer
  5th National Infection Biology Meeting
- Place of Presentation
  Umea, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Characterizing Bacterial Cell Wall Composition using cryo-XPS and Multivariate Analysis2011
- Author(s)
  Madeleine Ramstedt, Ryoma Nakao, Sun Nyunt Wai, Bernt Eric Uhlin, Jean-Prancois Boily
- Organizer
  MRS Spring Meeting and Exhibit
- Place of Presentation
  San Francisco, CA
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] う蝕原性Streptococcus mutans smooth-colony-variant出現メカニズムと病原性発現に関する検討2010
- Author(s)
  成澤直規、伊藤達朗、鈴木奈緒央未、佐藤裕、落合邦康、中尾龍馬、泉福英信
- Organizer
  第52回歯科基礎医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390506
[Presentation] Effect of the kil gene in plasmid ColE1 on E. coli biofilm formation2010
- Author(s)
  Ryoma Nakao, Madeleine Ramstedt, Sun Nyunt Wai, and Bernt Eric Uhlin
- Organizer
  Biofilms
- Place of Presentation
  Winchester, UK
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Effect of the kil gene in plasmid ColE1 on E.coli biofilm formation2010
- Author(s)
  Ryoma Nakao, Madeleine Ramstedt, Sun Nyunt Wai, Bernt Eric Uhlin
- Organizer
  Biofilms 4
- Place of Presentation
  Winchester, UK
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] う蝕原性Streptococcus mutans smooth-colony-variant出現メカニズム病原性発現に関する検討2010
- Author(s)
  成沢直規、伊藤達朗、鈴木奈央未、佐藤裕、落合邦康、中尾龍馬、泉福英信
- Organizer
  第52回歯科基礎医学会
- Place of Presentation
  千葉
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21390506
[Presentation] Streptococcus mutansにおけるバイオフィルム非形成自然変異株の出現機構2010
- Author(s)
  成澤直規、中尾龍馬、泉福英信
- Organizer
  バイオフィルム研究会
- Place of Presentation
  静岡県富士宮市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] う蝕原性Streptococcus mutans smooth-colony-variant出現メカニズムと病原性発現に関する検討2010
- Author(s)
  成澤直規、伊藤龍朗、鈴木奈央未、佐藤裕、落合邦康、中尾龍馬、泉福英信
- Organizer
  第52回歯科基礎医学会学術集会・総会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] 歯周病原性細菌Porphyromonasgingivalisの外膜ヴェシクル産生に寄与する遺伝子の探索2008
- Author(s)
  中尾龍馬、泉福英信、渡辺治雄
- Organizer
  第6回感染症沖縄フォーラム
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-19791360
[Presentation] A heat-labile substance in the culture supernatant of Porphyromonas gi ngivalis inhibits biofilm formation of Aggregatibacter actinomycetemcomi tans2007
- Author(s)
  中尾龍馬
- Organizer
  第4回口腔バイオフィルム研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19791360
[Presentation] Porphyromonas gingivalisのバイオフィルム形成における外膜タンパクのOMP85ホ毛ログの修飾糖鎖の役割2007
- Author(s)
  中尾龍馬
- Organizer
  日大生物資源化学部主催講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19791360
[Presentation] PorphyromonasgingivalisのGalEに依存した外膜タンパクOMP85のグリコシレーション2007
- Author(s)
  中尾龍馬、泉福英信
- Organizer
  第49回歯科基礎医学会学術集会・総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19791360
[Presentation] ワークショップ4歯周内科への道を探る〜抗菌化学療法の新しい役割〜生物学的プラークコントロールの将来性2007
- Author(s)
  菅野直之、中尾龍馬、泉福英信
- Organizer
  第55回日本化学療法学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19791360
[Presentation] X-ray photoelectron spectroscopy of intact bacterial cells can help evaluate changes in cell wall composition with respect to lipid, sugar, and peptide
- Author(s)
  Madeleine Ramstedt, Ryoma Nakao, Laura Leone, Andrey Shchukarev, Per Persson, Jean-Francois Boily, Sun Nyunt Wai, Bernt Eric Uhlin
- Organizer
  Nobel conference on biofilm formation, its clinical impact and potential treatment
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Immunological properties of outer membrane vesicles from Porphyromonas gingivalis
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Akira Ainai, Makoto Ohnishi, Haruo Watanabe, Hidenobu Senpuku
- Organizer
  5th National Infection Biology Meeting
- Place of Presentation
  Umeå, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Porphyromonas gingivalis 外膜ヴェシクルに反応するヒト血清抗体
- Author(s)
  中尾龍馬, 大西真, 渡邉治雄, 泉福英信
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Humoral immunity against Porphyromonas gingivalis in mice intranasally vaccinated with combination of outer membrane vesicles and synthetic double-stranded RNA
- Author(s)
  Ryoma Nakao, Dongying Bai, Makoto Ohnishi, Hiroshi Uematsu, Akira Ainai, Hideki Hasegawa, Hidenobu Senpuku
- Organizer
  第16回日本ワクチン学会学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Role of Outer Membrane Vesicles of Porphyromonas gingivalis in Immunopathology of Periodontitis in Human
- Author(s)
  Ryoma Nakao, Shogo Takashiba, Hideki Hasegawa, Haruo Watanabe, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  第34回内藤カンファレンス感染・炎症・免疫
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Immunoreactive antigens recognized by sera of mice intranasally immunized with outer membrane vesicles of Porphyromonas gingivalis
- Author(s)
  DongYing Bai, Ryoma Nakao, Hidenobu Senpuku
- Organizer
  British Society for Immunology BSI2013
- Place of Presentation
  Liverpool, UK
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Streptococcus mutans におけるバイオフィルム非形成自然変異株の出現機構
- Author(s)
  成澤直規, 中尾龍馬, 泉福英信
- Organizer
  バイオフィルム研究会
- Place of Presentation
  静岡県富士宮市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Effect of Porphyromonas gingivalis outer membrane vesicles on gingipain-mediated detachment of cultured oral epithelial cells and immune responses
- Author(s)
  Ryoma Nakao, Shogo Takashiba, Saori Kosono, Minoru Yoshida, Haruo Watanabe, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  British Society for Immunology BSI2013
- Place of Presentation
  Liverpool, UK
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Enhanced biofilm formation by Escherichia coli carrying a commonly occurring plasmid gene, " kil "
- Author(s)
  Ryoma Nakao, Sun Nyunt Wai, Bernt Eric Uhlin
- Organizer
  Nobel conference on biofilm formation, its clinical impact and potential treatment
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] 普遍的なプラスミド遺伝子kilは、大腸菌のバイオフィルム形成を増す
- Author(s)
  中尾龍馬
- Organizer
  日本細菌学会　第7回若手研究者育成のためのワークショップ「若手研究者によるバイオフィルム研究ワークショップ」
- Place of Presentation
  東京都新宿区
- Invited
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Role of outer membrane vesicles of Porphyromonas gingivalis for a mucosal immune response
- Author(s)
  Hidenobu Senpuku, Ryoma Nakao
- Organizer
  First International Conference on Porphyromonas gingivalis and Related Bacterial Species
- Place of Presentation
  Nagasaki
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] I. Effect of deletion of LPS core oligosaccharides on Biofilm formation and OMV formulation. II. Immunological Properties of Outer Membrane Vesicles from Porphyromonas gingivalis
- Author(s)
  Ryoma Nakao
- Organizer
  1st Cell Adhesion Workshop
- Place of Presentation
  Umeå, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Outer membrane vesicles of Porphyromonas gingivalis carry a variety of antigens and virulence factors
- Author(s)
  中尾龍馬, 泉福英信
- Organizer
  第54回歯科基礎医学会学術集会・総会
- Place of Presentation
  郡山市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Outer membrane vesicles of Porphyromonas gingivalis Bind to Magnetic Beads Coated with Epoxy Groups in a Noncovalnent, Species-Specific manner
- Author(s)
  Ryoma Nakao, Hidenobu Senpuku
- Organizer
  第５６回歯科基礎医学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Dose-dependent effect of the kil gene on biofilm formation of E. coli
- Author(s)
  Ryoma Nakao, Madeleine Ramstedt, Sun Nyunt Wai, and Bernt Eric Uhlin
- Organizer
  Eurobiofilms 2011
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Humoral immunityagainst Porphyromonas gingivalis in mice intranasally vaccinated with outer membrane vesicles
- Author(s)
  Dongying Bai, Ryoma Nakao, Hidenobu Senpuku
- Organizer
  First International Conference on Porphyromonas gingivalis and Related Bacterial Species
- Place of Presentation
  Nagasaki
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Characterizing Bacterial Cell Wall Composition using cryo-XPS and Multivariate Analysis
- Author(s)
  Madeleine Ramstedt, Ryoma Nakao, Sun Nyunt Wai, Bernt Eric Uhlin, Jean-Francois Boily
- Organizer
  MRS Spring Meeting and Exhibition
- Place of Presentation
  San Francisco, CA
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Monitoring bacterial cell wall composition using cryo-XPS and multivariate analysis
- Author(s)
  Madeleine Ramstedt, Ryoma Nakao, Sun Nyunt Wai, Bernt Eric Uhlin, Jean-Francois Boily
- Organizer
  5th National Infection Biology Meeting
- Place of Presentation
  Umeå, Sweden
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] プロポリスの歯周病原細菌に対する抗菌作用の検討
- Author(s)
  吉益由莉　泉福英信　中尾龍馬
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Ig responses inmice after intranasal immunization of Porphyromonas gingivalis outer membrane vesicles
- Author(s)
  Ryoma Nakao, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] 高速原子間力顕微鏡を用いた大腸菌からの外膜ヴェシクルの放出
- Author(s)
  菊島健児、中尾龍馬
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] 普遍的なプラスミド遺伝子kil は,大腸菌のバイオフィルム形成を増す
- Author(s)
  中尾龍馬
- Organizer
  日本細菌学会第7回若手研究者育成のためのワークショップ「若手研究者によるバイオフィルム研究」
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Feasibility of intranasal vaccine for periodontal diseases using outer membrane vesicles
- Author(s)
  Ryoma Nakao, Bai Dong Yng, Hideki Hasegawa, Akira Ainai, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  Gordon Research Conference : Periodontal Diseases
- Place of Presentation
  Davidson, NC
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] クロストリジウム属細菌が産生するメンブランベシクルは宿主細胞と相互作用する
- Author(s)
  永山恭子、尾花望、中尾龍馬、泉福英信、中村幸治、野村暢彦
- Organizer
  環境微生物系学会合同大会2014
- Place of Presentation
  浜松
- Year and Date
  2014-10-21 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] gingivalis Membrane Vesicles Bind to Epoxy Groups on Magnetic Beads in a Species-Specific Manner
- Author(s)
  Ryoma Nakao, Nozomu Obana, Nobuhiko Nomura, Makoto Ohnishi, Hidenobu Senpuku. P
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] Imaging of Porphyromonas gingivalis infection using quantum dots
- Author(s)
  菊島健児、中尾龍馬、樋口秀男
- Organizer
  第43回日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] ウェルシュ菌が産生するメンブランベシクルは宿主の免疫応答を誘導する
- Author(s)
  永山恭子、尾花望、中尾龍馬、泉福英信、中村幸治、野村暢彦
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26462866
[Presentation] Immunological properties of outer membrane vesicles from Porphyromonas gingivalis
- Author(s)
  Ryoma Nakao, Hideki Hasegawa, Akira Ainai, Haruo Watanabe, Makoto Ohnishi, Hidenobu Senpuku
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-22791822
[Presentation] う蝕原性Streptococcus mutans smooth-colony-variant 出現メカニズムと病原性発現に関する検討
- Author(s)
  成澤直規, 伊藤龍朗, 鈴木奈央未, 佐藤裕, 落合邦康, 中尾龍馬,泉福英信
- Organizer
  第52回歯科基礎医学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791822

1. SENPUKU Hidenobu (20250186)

# of Collaborated Projects: 8 results

# of Collaborated Products: 50 results
2. 平山悟 (70778555)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
3. WATANABE Haruo (70142130)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. OGATA Yorimasa (90204065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Ikeda Tsuyoshi (80295138)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 尾花望 (00722688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 相内章 (10572133)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 野村暢彦 (60292520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. KAWARAI Taketo (90409079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUGANO Naoyuki (30246904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OHNISHI Makoto (10233214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. TAKAHASHI Hideyuki (60321866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HIGUCHI Hideo (90165093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. HANADA Nobuhiro (70180916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Yonezawa Hideo (60453528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Miyazaki Hidetaka (70420271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TASHIRO YOSUKE (30589528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 古川壮一 (40339289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 佐藤勉 (60130671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 成澤直規 (90632034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 工藤敏文 (50431911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 金原和秀 (30225122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 川崎忠寛 (10372533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 佐々木祐生 (80808668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 上野尚雄 (90450832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 佐々木永太 (40762216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. 井上智 (90213157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 山口雄大 (40726080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
29. Lee Seohyun (00847973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 矢原寛子 (10757488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 安部公博 (10748940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 木村聡一郎 (60408870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. NAGASAWA RYO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAO Ryoma 中尾 龍馬

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Acceleration of unexplored periodontal disease vaccine development by intranasal administration of bacterial membrane vesiclesPrincipal Investigator

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Dynamic behavior and pathological significance of small RNA in outer membrane vesicles of periodontopathic bacteriaPrincipal Investigator

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Periodontopathic bacterial outer membrane vesicles: Biogenesis and relation to development of chronic inflammation and carcinogenesisPrincipal Investigator

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Novel nano paticle vaccine | Biogenesis and medical application of outer membrane vesiclesPrincipal Investigator

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Immunopathology of outer membrane vesicles of periodontopathic bacteriaPrincipal Investigator

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Principal Investigator

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Investigation of biofilm-related molecules in Porphyromonas gingivalisPrincipal Investigator

NAKAO Ryoma 中尾龍馬