OKADA Takaho 岡田恭穂

Researcher Number	10375074
Affiliation (based on the past Project Information) *help	2013: 東北大学, 病院, 助教 2011 – 2013: 東北大学, 大学病院, 助教 2010 – 2011: 東北大学, 病院, 助教 2007: Tohoku University, Hospital, Assistant Professor
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator General surgery / Digestive surgery
Keywords	Principal Investigator 長期生存膵癌 / 遺伝子不安定性 / 膵管癌 / 通常型膵癌 / 早期膵癌 / 通常型膵管癌 / マイクロサテライト不安定性 Except Principal Investigator SEREX法 / 樹状細胞 / 免疫療法 … More / WT1 / 膵癌 / intralymphatic injection / clinical trial / interferon alpha / dendritic cells / immunotherrapy / cancer antigen / SEREX method / pancreatic cancer / 発現プロファイル / マイクロアレイ / SEREX / ティッシューアレイ / 抗原負荷 / IFN-α / 腫瘍抗原 / survivin / IL-12 / リンパ管内投与 / 臨床試験 / インターフェロンα / 免疫治療 / 癌抗原 / 化学療法 / 腫瘍特異的抗原 / WT1ペプチドワクチン / プロテオミクス / 腫瘍関連抗原 / 胆道癌 / ペプチドワクチン Less

Immune response to frameshift mutation-derived peptides in microsatellite instability positive pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  OKADA Takaho
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
Establishment of specific cancer vaccination therapy for pancreatic and biliary cancer.
- Principal Investigator
  
  EGAWA Shinichi
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
Identificaiton of tumor associated antigen for pancreatic cancer by SEREX method using sera from patients with advanced disease who underwent immunotherapy
- Principal Investigator
  
  EGAWA Shinichi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Tohoku University

All 2014 2013 2012 2011 2006 Other

All Journal Article Presentation

[Journal Article] Phase II clinical study of alternate-day oral therapy with S-1 as first-line chemotherapy for locally advanced and metastatic pancreatic cancer2014
- Author(s)
  Yamaue H, et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 73(1) Issue: 1 Pages: 97-102
- DOI
  10.1007/s00280-013-2323-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390253, KAKENHI-PROJECT-23390331, KAKENHI-PROJECT-24592037, KAKENHI-PROJECT-25670560
[Journal Article] Pancreatic intraepithelial neoplasia-3 with localized acute pancreatitis in the main pancreatic duct2013
- Author(s)
  Okada T, Motoi F, Kanno A, Masamune A, Ishida K, et al
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 6(2) Issue: 2 Pages: 164-168
- DOI
  10.1007/s12328-013-0368-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791515
[Journal Article] Neoadjuvant chemotherapy with gemcitabine and S-1 for resectable and borderline pancreatic ductal adenocarcinoma : results from a prospective multi-institutional phase 2 trial2013
- Author(s)
  Motoi F, et al
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 20(12) Issue: 12 Pages: 3794-801
- DOI
  10.1245/s10434-013-3129-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390253
[Journal Article] 術前化学療法施行後、腹腔動脈合併尾側膵切除にてR0手術を施行し得た局所進行膵体部癌の1例2012
- Author(s)
  岡田恭穂、櫻井直樹、山本久仁治、元井冬彦、柿崎泰明、田村元、海野倫明、飯澤肇
- Journal Title
  
  癌と化学療法
  
  Volume: 39 Pages: 135-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791515
[Journal Article] Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system2012
- Author(s)
  Shima K, et al
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 31 Issue: 1 Pages: 55-61
- DOI
  10.1186/1756-9966-31-55
- URL
  http://www.jeccr.com/content/31/1/55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390253, KAKENHI-PROJECT-23590452, KAKENHI-PROJECT-23791514, KAKENHI-PROJECT-23791515, KAKENHI-PROJECT-24390118, KAKENHI-PROJECT-24659487
[Journal Article] 膵体尾部切除に対するクリニカルパス2012
- Author(s)
  岡田恭穂、江川新一、海野倫明
- Journal Title
  
  胆と膵
  
  Volume: 33 Pages: 771-776
- Data Source
  KAKENHI-PROJECT-23791515
[Journal Article] Severe cholestatic liver failure associated with gemcitabine adjuvant monotherapy for pancreatic cancer2011
- Author(s)
  Okada T, et al
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 4 Pages: 391-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390253
[Journal Article] 膵癌における外科手術-適応・術式の動向-2011
- Author(s)
  岡田恭穂,江川新一,元井冬彦,乙供茂,坂田直昭,林洋毅,吉田寛,力山敏樹,片寄友,海野倫明
- Journal Title
  
  胆と膵
  
  Volume: 32(4) Pages: 301-307
- Data Source
  KAKENHI-PROJECT-23791515
[Journal Article] Severe colestatic liver failure associated with gemcitabine adjuvant monotherapy for pancreatic cancer2011
- Author(s)
  Okada T, Egawa S, Motoi F, Yamamoto K, Ottomo S, Sakata N, Rikiyama T, Katayose Y, Unno M
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 4 Issue: 6 Pages: 391-395
- DOI
  10.1007/s12328-011-0257-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390253, KAKENHI-PROJECT-23791515
[Journal Article] 腫瘍マーカーの種類と特徴　DU-PAN-22011
- Author(s)
  岡田恭穂、元井冬彦、海野倫明
- Journal Title
  
  臨床と研究
  
  Volume: 88 Pages: 957-959
- Data Source
  KAKENHI-PROJECT-23791515
[Journal Article] 膵癌における外科手術　-適応・術式の動向-2011
- Author(s)
  岡田恭穂、江川新一、元井冬彦、乙供茂、坂田直昭、林洋毅、吉田寛、力山敏樹、片寄友、海野倫明
- Journal Title
  
  胆と膵
  
  Volume: 32 Pages: 301-307
- Data Source
  KAKENHI-PROJECT-23791515
[Journal Article] A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers2006
- Author(s)
  Okada T, et. al.
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 191-197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390352
[Journal Article] A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers.2006
- Author(s)
  Okada T, et. al.
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 191-197
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390352
[Presentation] 過去の手術症例の術式・膵切除断端・多中心性所見からみたIPMNの最適術式と経過観察法についての検討2013
- Author(s)
  岡田恭穂、水間正道、川口　桂、藪内伸一、深瀬耕二、乙供　茂、坂田直昭、林　洋毅、中川　圭、森川孝則、吉田　寛、元井冬彦、内藤　剛、片寄友、海野倫明
- Organizer
  第75回日本臨床外科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 慢性膵炎手術に対する栄養評価を重視したクリニカルバスの運用評価2013
- Author(s)
  岡田恭穂、元井冬彦、乙供茂、水間正道、坂田直昭、青木豪、深瀬耕二、林洋毅、中川圭、吉田寛、内藤剛、片寄友、海野倫明
- Organizer
  第25回日本肝胆膵外科学会・学術集会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] ERASプロトコールを導入した膵頭十二指腸切除(PD)クリティカルパスの運用成績2013
- Author(s)
  岡田恭穂、海野倫明
- Organizer
  第15回医療マネジメント学会学術総会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 栄養・代謝管理を重視した膵頭十二指腸切除術における周術期管理標準化の試み2013
- Author(s)
  岡田恭穂、吉田寛、海野倫明
- Organizer
  日本外科代謝栄養学会第50回学術集会
- Place of Presentation
  東京都千代田区
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 超高齢者に膵頭十二指腸切除術を適用する際のリスクファクターは何か?2013
- Author(s)
  岡田恭穂、元井冬彦、青木豪、深瀬耕二、乙供茂、坂田直昭、大塚英郎、水間正道、林洋毅、中川圭、森川孝則、吉田寛、内藤剛、三浦康、片寄友、柴田近、江川新一、海野倫明
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 膵頭十二指腸切除術における,ERASプログラムを導入したクリニカルバス運用による周術期管理の改善効果2013
- Author(s)
  岡田恭穂、元井冬彦、水間正道、林洋毅、中川圭、乙供茂、吉田寛、内藤剛、片寄友、海野倫明
- Organizer
  第68回日本消化器外科学会総会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] FDGｰPETの膵管内乳頭粘液性腫瘍(IPMN)における診断能と外科切除例における予後予測能について2013
- Author(s)
  岡田恭穂、元井冬彦、水間正道、川口　桂、青木豪、藪内伸―、深瀬耕二、坂田直昭、林洋毅、中川圭、吉田寛、内藤剛、片寄友、海野倫明
- Organizer
  第11回日本消化器外科学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] IPMNの手術治療方針:特に腫瘍本体の性状・膵断端の所見と残膵局所再発との関連について2012
- Author(s)
  岡田恭穂、江川新一、乙供茂、元井冬彦、林洋毅、中川圭、水間正道、石田晶玄、深瀬耕二、坂田直昭、大塚英郎、森川孝則、小野川徹、吉田寛、内藤剛、力山敏樹、片寄友、海野倫明
- Organizer
  第24回日本肝胆膵外科学会・学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 慢性膵炎手術に対するクリニカルバス適用の取り組み2012
- Author(s)
  岡田恭穂、元井冬彦、乙供茂、坂田直昭、吉田寛、林洋毅、力山敏樹、片寄友、江川新一、海野倫明
- Organizer
  第67回日本消化器外科学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] ERASプロトコールを導入した膵頭十二指腸切除(PD)クリニカルパス使用による一貫したPD周術期栄養管理の効果2012
- Author(s)
  岡田恭穂、吉田寛、海野倫明
- Organizer
  第20回日本消化器関連学会週間
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] IPMN初回手術時の残膵・膵断端の所見と残膵局所再発との関連について2012
- Author(s)
  岡田恭穂、江川新一、乙供茂、元井冬彦、水間正道、林洋毅、中川圭、青木豪、深瀬耕二、大塚英郎、坂田直昭、吉田寛、内藤剛、片寄友、海野倫明
- Organizer
  第74回日本臨床外科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 膵癌根治手術術前検査としてのFDG- PET検査の重要性2012
- Author(s)
  岡田恭穂、元井冬彦、乙供茂、水間正道、中川圭、林洋毅、石田晶玄、深瀬耕二、大塚英郎、坂田直昭、森川孝則、小野川徹、吉田寛、内藤剛、力山敏樹、片寄友、江川新一、海野倫明
- Organizer
  第43回日本膵臓学会大会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 膵癌根治手術術前検査としてのFDG-PET検査の重要性2012
- Author(s)
  岡田恭穂、元井冬彦,乙供茂,水間正道ほか
- Organizer
  第43回日本膵臓学会大会
- Place of Presentation
  山形
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 膵頭十二指腸切除術における周術期管理の標準化は合併症発生・治療と在院日数に良い影響を与えたか?2011
- Author(s)
  岡田恭穂、元井冬彦、中川圭、林洋毅、小野川徹、吉田寛、力山敏樹、片寄友、江川新一、海野倫明
- Organizer
  第66回日本消化器外科学会総会
- Place of Presentation
  愛知県
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 膵管減圧術後膵頭部で再燃し、Frey手術を付加して優れた除痛効果をもたらした3症例2011
- Author(s)
  岡田恭穂、江川新一、元井冬彦、坂田直昭、乙供茂、深瀬耕二、水間正道、大塚英郎、林洋毅、森川孝則、中川圭、吉田寛、小野川徹、力山敏樹、片寄友、江川新一、海野倫明
- Organizer
  第42回日本膵臓学会大会
- Place of Presentation
  青森県
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 膵癌術前(進行度)診断ツールとしてのFDG-PET検査の有用性2011
- Author(s)
  岡田恭穂、元井冬彦、乙供茂、坂田直昭、深瀬耕二、水間正道、大塚英郎、中川圭、林洋毅、吉田寛、小野川徹、力山敏樹、片寄友、江川新一、海野倫明
- Organizer
  第111回日本外科学会総会
- Place of Presentation
  紙上開催
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 膵癌術前(進行度)診断ツールとしてのFDG-PET検査の有用性2011
- Author(s)
  岡田恭穂、元井冬彦,乙供茂,坂田直昭ほか
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京予定→紙上開催
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] 当科における膵体尾部切除術クリニカルパスの導入と運用評価2011
- Author(s)
  岡田恭穂、元井冬彦、乙供茂、坂田直昭、深瀬耕二、大塚英郎、水間正道、中川圭、林洋毅、森川孝則、吉田寛、力山敏樹、片寄友、江川新一、海野倫明
- Organizer
  第23回日本肝胆膵外科学会・学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23791515
[Presentation] Pilot trial of Wilms Tumor 1 (WT1) peptide vaccine therapy for chemorefractory advanced pancreatic cancer2011
- Author(s)
  Egawa S, Okada T, Hayashi H, Kitamura Y, Ottomo S, Fukase K, Ohtsuka H, Morikawa T, Mizuma M, Sakata N, Nakagawa K, Yoshida H, Onogawa T, Motoi F, Naito T, Rikiyama T, Katayose Y, Nishida S, Oka Y, Sugiyama H, Unno M
- Organizer
  5^<th> Intenational Conference of WT1 in Human Neoplasia
- Place of Presentation
  イタリア・トリノ
- Year and Date
  2011-04-15
- Data Source
  KAKENHI-PROJECT-22390253
[Presentation] 3種類の膵疾患手術に対するクリニカルパス適用への取り組み-膵疾患手術の標準化を目指して-
- Author(s)
  岡田恭穂、、元井冬彦、乙供茂、坂田直昭、深瀬耕二、大塚英郎、水間正道、中川圭、林洋毅、吉田寛、力山敏樹、片寄友、江川新一、海野倫明
- Organizer
  第73回日本臨床外科学会総会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23791515

1. SAKATA Naoaki (50431565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. EGAWA Shinichi (00270679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. HAYASHI Hiroki (30422124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. FUKUYAMA Shoji (10344673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MOTOI Fuyuhiko (30343057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 砂村眞琴 (10201584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 阿部忠義 (50361077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 武田和憲 (20171639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 横山忠明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OKADA Takaho 岡田 恭穂

Research Projects

Research Products

Co-Researchers

Immune response to frameshift mutation-derived peptides in microsatellite instability positive pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of specific cancer vaccination therapy for pancreatic and biliary cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identificaiton of tumor associated antigen for pancreatic cancer by SEREX method using sera from patients with advanced disease who underwent immunotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Phase II clinical study of alternate-day oral therapy with S-1 as first-line chemotherapy for locally advanced and metastatic pancreatic cancer2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pancreatic intraepithelial neoplasia-3 with localized acute pancreatitis in the main pancreatic duct2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neoadjuvant chemotherapy with gemcitabine and S-1 for resectable and borderline pancreatic ductal adenocarcinoma : results from a prospective multi-institutional phase 2 trial2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 術前化学療法施行後、腹腔動脈合併尾側膵切除にてR0手術を施行し得た局所進行膵体部癌の1例2012

Author(s)

Journal Title

Data Source

[Journal Article] Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system2012

Author(s)

Journal Title

DOI

URL

Data Source

[Journal Article] 膵体尾部切除に対するクリニカルパス2012

Author(s)

Journal Title

Data Source

[Journal Article] Severe cholestatic liver failure associated with gemcitabine adjuvant monotherapy for pancreatic cancer2011

Author(s)

Journal Title

Data Source

[Journal Article] 膵癌における外科手術-適応・術式の動向-2011

Author(s)

Journal Title

Data Source

[Journal Article] Severe colestatic liver failure associated with gemcitabine adjuvant monotherapy for pancreatic cancer2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 腫瘍マーカーの種類と特徴 DU-PAN-22011

Author(s)

Journal Title

Data Source

[Journal Article] 膵癌における外科手術 -適応・術式の動向-2011

Author(s)

Journal Title

Data Source

[Journal Article] A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers.2006

Author(s)

Journal Title

OKADA Takaho 岡田恭穂

[Journal Article] 腫瘍マーカーの種類と特徴　DU-PAN-22011

[Journal Article] 膵癌における外科手術　-適応・術式の動向-2011