NAGAI TAKU 永井拓

… Alternative Names

NAGAI Taku 永井拓

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Researcher Number	10377426
Other IDs
External Links
Affiliation (Current)	2025: 藤田医科大学, 精神・神経病態解明センター, 教授
Affiliation (based on the past Project Information) *help	2024: 藤田医科大学, 精神・神経病態解明センター, 教授 2022: 藤田医科大学, 精神・神経病態解明センター, 教授 2019 – 2022: 藤田医科大学, その他部局等, 教授 2009 – 2019: Nagoya University, 医学部附属病院, 准教授 2008: Nagoya University, 大学院医学系研究科, 特任講師 … More 2007 – 2008: Nagoya University, 大学院・医学系研究科, 特任講師 2007: 名古屋大学, 大学院・医学系研究科, 講師 2006 – 2007: 名古屋大学, 医学系研究科, 特任講師 2006: 名古屋大学, 大学院医学系研究科, 特任講師 2005: 金沢大学, 自然科学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / Basic / Social brain science / Pharmaceutical Sciences and related fields / Pharmacology in pharmacy Except Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related / Neurophysiology / General neuroscience / Biological pharmacy / Experimental pathology / Psychiatric science
Keywords	Principal Investigator 統合失調症 / 薬理学 / 神経化学 / ドパミン / 意思決定 / 副作用 / パーキンソン病 / コピー数多型 / マウス / 遺伝子変異 … More / ドーパミン / 情動 / リン酸化シグナル / 薬物反応性 / 可視化 / 神経発達障害 / 免疫 / アストロサイト / 神経発達 / メタンフェタミン / 転写因子 / 薬物依存 / 神経科学 / グルタミン酸受容体 / プロテオーム / 蛋白質 / 基礎研究 / 脳・神経 / リンパ芽球様細胞株 / タンパク質 / 二次元電気泳動法 / プロテアーゼ活性化受容体 / プラスミン / 組織プラスミノーゲン活性化因子 / プロテアーゼ … More Except Principal Investigator 統合失調症 / 神経科学 / 動物モデル / 脳神経疾患 / RAGE / ABAD / シナプス可塑性 / Npas4 / ストレス / メタンフェタミン / 認知機能 / 神経スパイン / twinfilin-1 / リーリン / 抗精神病薬 / Ｒhoキナーゼ / ROCK2阻害薬 / Fasudil / 抗精神病作用 / Rhoキナーゼ / 学習 / プロテオミクス解析 / リン酸化 / シグナル伝達 / 遺伝子発現 / 神経活動 / 学習・記憶 / 情動行動 / ニューロモジュレーター / リン酸化プロテオミクス解析 / 細胞内シグナル / キンドリング / Homer1a / トランスジェニックマウス / イメージング創薬 / DREADDシステム / 神経回路 / 大脳基底核 / 島皮質 / 覚せい剤 / 薬理学 / 意思決定 / apoptosis / mitochondria / β-amyloid / neuron cultures / Alzheimer's disease / 透過性遷移孔 / アミロイドβペプチド / アポトーシス / ミトコンドリア / β-アミロイド / 神経細胞 / アルツハイマー病 / 行動解析 / アクチン結合蛋白 / 蛋白リン酸 / 海馬神経 / BDNF/TekB/Akiシグナル / 疾患モデルマウス / 蛋白リン酸化 / 記憶障害 / promoter / glucocorticoid / stress / NPAS4 / DNAメチル化 / プロモーター / グルココルチコイド / 転写制御 / D-セリン / 炎症性サイトカイン / アストログリア / 神経－グリア相互作用 / エンドサイトーシス / IFITM3 / polyI:C / 神経-グリア相互作用 / アストログリア細胞 / 神経発達障害 / 遺伝子翻訳後修飾 / タンパク発現 / プロテオーム / 双極性障害 / 神経化学 / 遺伝子 / 行動学 / プロテインキナーゼA / ドーパミンD1受容体 / モルヒネ / ニコチン / 認知症 / 覚せい剤精神病 / 薬物依存 / ドーパミン / プラスミン / 組織プラスミノーゲン活性化因子 Less

パーキンソン病における意思決定障害の分子・神経メカニズム解明と新規治療薬開発Principal Investigator
- Principal Investigator
  
  永井拓
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fujita Health University
Study on the regulation mechanism of neural spine morphology and cognitive function by twinfilin-1
- Principal Investigator
  
  山田清文
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fujita Health University
  Nagoya University
Study on development of novel antipsychotics based on reverse translational researchPrincipal Investigator
- Principal Investigator
  
  Nagai Taku
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fujita Health University
Genomic analysis-based neuropharmacological study on basal ganglia-thalamocortical circuits for new drug discovery in schizophrenia
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Nagoya University
Development an in vivo real-time analytical system that can predict dependency and rewarding effects of novel compoundsPrincipal Investigator
- Principal Investigator
  
  Nagai Taku
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Nagoya University
Study on the neural mechanism controlling emotional behaviorsPrincipal Investigator
- Principal Investigator
  
  Nagai Taku
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Fujita Health University
  Nagoya University
Study on regulatory mechanism of neural activity and emotional behavior by intracellular signals
- Principal Investigator
  
  Kaibuchi Kozo
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Nagoya University
Development of a new transgenic mouse model as a platform for the imaging-based drug discovery and development
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Study on the neuronal circuit and molecular mechanis underlying decision-making and its application for drug development
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Study on the neurodevelopmental abnormalities induced by the innate immune activation during perinatal periodPrincipal Investigator
- Principal Investigator
  
  NAGAI Taku
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nagoya University
Roles of Girdin in synaptic plasticity and memory
- Principal Investigator
  
  ASAI Naoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University
Role of neuronal PAS domain 4 (Npas4) in psychiatric disorder.
- Principal Investigator
  
  HIBI YOKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
ROLE OF TRANSCRIPTION FACTOR NPAS4 IN DRUG DEPENDENCEPrincipal Investigator
- Principal Investigator
  
  NAGAI Taku
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
Functional analysis of IFITM3 in neurodevelopmental impairments
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Identification of drug target for novel antipsychotics based on proteomic approachPrincipal Investigator
- Principal Investigator
  
  NAGAI Taku
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
Influences of genetic and environmental factors on schizophrenia
- Principal Investigator
  
  NABESHIMA Toshitaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Meijo University
プロテオーム解析による統合失調症と双極性障害の病態に共通する分子の探索
- Principal Investigator
  
  尾崎紀夫
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Nagoya University
ANALYSES OF DYNAMIC CHANGES AND THE FUNCTION OF TISSUE PLASMINOGEN ACTIVATOR IN ANIMAL MODELS OF DOPAMINE-RELATED MENTAL DISORDERS
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Proteomics analysis in schizophreniaPrincipal Investigator
- Principal Investigator
  
  NAGAI Taku
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
Molecular mechanisms of mitochondrial dysfunction and neurotoxicity induced by Aβ-ARAD interaction
- Principal Investigator
  
  TAKUMA Kazuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kanazawa University
分泌型セリンプロテアーゼによるドパミン遊離調節機構の解明Principal Investigator
- Principal Investigator
  
  永井拓
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
  Kanazawa University

[Book] 実験薬理学実践行動薬理学(日本薬理学会編)(依存性薬物による精神障害の分子機序.)2010
- Author(s)
  永井拓、鍋島俊隆、山田清文
- Publisher
  金芳堂、京都
- Data Source
  KAKENHI-PROJECT-19390062
[Book] 第II編第4章報酬機構関連3依存性薬物による精神障害の分子機序「実践行動薬理学」(編集・(社)日本薬理学会編集責任者・武田弘志,辻稔,赤池昭紀)2010
- Author(s)
  永井拓, 鍋島俊隆, 山田清文
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-21790067
[Book] 実践行動薬理学(第□編応用編:行動薬理研究の現在、第4章報酬機構関連、3.依存性薬物による精神障害の分子機序)2010
- Author(s)
  永井拓、鍋島俊隆、山田清文
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] An evaluation method for developing abuse-deterrent opioid formulations with agonist and antagonist combinations using conditioned place preference.2023
- Author(s)
  Zhang, X., Kitaichi, K., Mouri A., Zhou, X., Nabeshima, T., Yamada, K., Nagai, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 639 Pages: 100-105
- DOI
  10.1016/j.bbrc.2022.11.072
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07931
[Journal Article] Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.2023
- Author(s)
  Tanaka R, Liao J, Hada K, Mori D, Nagai T, Matsuzaki T, Nabeshima T, Kaibuchi K, Ozaki N, Mizoguchi H, Yamada K.
- Journal Title
  
  Pharmacological Research
  
  Volume: 187 Pages: 106589-106589
- DOI
  10.1016/j.phrs.2022.106589
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-23K27360
[Journal Article] DARPP-32/protein phosphatase 1 regulates Rasgrp2 as a novel component of dopamine D1 receptor signaling in striatum.2023
- Author(s)
  Kuroiwa, M., Shuto, T., Nagai, T., Amano, M., Kaibuchi, K., Nairn, A.C., Nishi, A.
- Journal Title
  
  Neurochem. Int.
  
  Volume: 162 Pages: 105438-105438
- DOI
  10.1016/j.neuint.2022.105438
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-23K24074
[Journal Article] Rho kinase inhibitors ameliorate cognitive impairment in a male mouse model of methamphetamine-induced schizophrenia2023
- Author(s)
  Liao Jingzhu、Dong Geyao、Zhu Wenjun、Wulaer Bolati、Mizoguchi Hiroyuki、Sawahata Masahito、Liu Yue、Kaibuchi Kozo、Ozaki Norio、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Pharmacological Research
  
  Volume: 194 Pages: 106838-106838
- DOI
  10.1016/j.phrs.2023.106838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-23K27360
[Journal Article] Clinical impact of standardized creatinine on dose adjustment of capecitabine2022
- Author(s)
  Ito, A., Ichikawa, K., Miyazaki, M., Sagara, A., Motegi, T., Ando, Y., Senzaki, K., Nagai, T., Yamada K.
- Journal Title
  
  Nagoya Journal of Medical Science
  
  Volume: 84 Issue: 3 Pages: 547-553
- DOI
  10.18999/nagjms.84.3.547
- ISSN
  0027-7622
- URL
  https://nagoya.repo.nii.ac.jp/records/2003747
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07082
[Journal Article] Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning2022
- Author(s)
  Yamahashi Y, Lin YH, Mouri A, Iwanaga S, Kawashima K, Tokumoto Y, Watanabe Y, Faruk MO, Zhang X, Tsuboi D, Nakano T, Saito N, Nagai T, Yamada K, Kaibuchi K.
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 27 Issue: 8 Pages: 3479-3492
- DOI
  10.1038/s41380-022-01643-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06427, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07931, KAKENHI-PUBLICLY-21H00196
[Journal Article] Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia.2022
- Author(s)
  Takase S, Liao J, Liu Y, Tanaka R, Miyagawa Y, Sawahata M, Sobue A, Mizoguchi H, Nagai T, Kaibuchi K, Ozaki N, Yamada K.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 15;931 Pages: 175207-175207
- DOI
  10.1016/j.ejphar.2022.175207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior2022
- Author(s)
  Tsuboi Daisuke、Otsuka Takeshi、Shimomura Takushi、Faruk Md Omar、Yamahashi Yukie、Amano Mutsuki、Funahashi Yasuhiro、Kuroda Keisuke、Nishioka Tomoki、Kobayashi Kenta、Sano Hiromi、Nagai Taku、Yamada Kiyofumi、Tzingounis Anastasios V.、Nambu Atsushi、Kubo Yoshihiro、Kawaguchi Yasuo、Kaibuchi Kozo
- Journal Title
  
  Cell Reports
  
  Volume: 40 Issue: 10 Pages: 111309-111309
- DOI
  10.1016/j.celrep.2022.111309
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-21K06427, KAKENHI-PROJECT-21K06428, KAKENHI-PROJECT-21K07257, KAKENHI-PROJECT-22K06438, KAKENHI-PROJECT-19KK0193, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07284, KAKENHI-PUBLICLY-21H00196, KAKENHI-PUBLICLY-22H04758, KAKENHI-PUBLICLY-22H04790, KAKENHI-PROJECT-20H03359
[Journal Article] Mice with exonic RELN deletion identified from a patient with schizophrenia have impaired visual discrimination learning and reversal learning in touchscreen operant tasks2022
- Author(s)
  Liao Jingzhu、Dong Geyao、Wulaer Bolati、Sawahata Masahito、Mizoguchi Hiroyuki、Mori Daisuke、Ozaki Norio、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 416 Pages: 113569-113569
- DOI
  10.1016/j.bbr.2021.113569
- NAID
  120007190677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Microinjection of Reelin into the mPFC prevents MK-801-induced recognition memory impairment in mice2021
- Author(s)
  Sawahata Masahito、Asano Hiroki、Nagai Taku、Ito Norimichi、Kohno Takao、Nabeshima Toshitaka、Hattori Mitsuharu、Yamada Kiyofumi
- Journal Title
  
  Pharmacological Research
  
  Volume: 173 Pages: 105832-105832
- DOI
  10.1016/j.phrs.2021.105832
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-19K07366, KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-21K19342
[Journal Article] Muscarinic signaling regulates voltage‐gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning2021
- Author(s)
  Faruk Md. Omar、Tsuboi Daisuke、Yamahashi Yukie、Funahashi Yasuhiro、Lin You‐Hsin、Ahammad Rijwan Uddin、Hossen Emran、Amano Mutsuki、Nishioka Tomoki、Tzingounis Anastasios V、Yamada Kiyofumi、Nagai Taku、Kaibuchi Kozo
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 160 Issue: 3 Pages: 325-341
- DOI
  10.1111/jnc.15555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16370, KAKENHI-PUBLICLY-21H00196, KAKENHI-PROJECT-21K06427, KAKENHI-PROJECT-21K06428, KAKENHI-PROJECT-20K07082
[Journal Article] Analysis of Reelin signaling and neurodevelopmental trajectory in primary cultured cortical neurons with RELN deletion identified in schizophrenia2021
- Author(s)
  Tsuneura Yumi、Sawahata Masahito、Itoh Norimichi、Miyajima Ryoya、Mori Daisuke、Kohno Takao、Hattori Mitsuharu、Sobue Akira、Nagai Taku、Mizoguchi Hiroyuki、Nabeshima Toshitaka、Ozaki Norio、Yamada Kiyofumi
- Journal Title
  
  Neurochemistry International
  
  Volume: 144 Pages: 104954-104954
- DOI
  10.1016/j.neuint.2020.104954
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-21K19342
[Journal Article] Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK2021
- Author(s)
  Ariza Anthony、Funahashi Yasuhiro、Kozawa Sachi、Omar Faruk Md.、Nagai Taku、Amano Mutsuki、Kaibuchi Kozo
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: - Issue: 6 Pages: 1774-1788
- DOI
  10.1111/jnc.15303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05209, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-17K07383, KAKENHI-PROJECT-18K14849
[Journal Article] Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons2021
- Author(s)
  Hada K, Wulaer B, Nagai T, Itoh N, Sawahata M, Sobue A, Mizoguchi H, Mori D, Kushima I, Nabeshima T, Ozaki N, Yamada K.
- Journal Title
  
  Mol Brain
  
  Volume: 14(1) Issue: 1 Pages: 21-21
- DOI
  10.1186/s13041-021-00735-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] AUTS2 regulation of synapses for proper synaptic inputs and social communication.2020
- Author(s)
  Hori Kei、Yamashiro Kunihiko、Nagai Taku、... Yamada Mitsuhiko、Yamada Kiyofumi、Hoshino Mikio
- Journal Title
  
  iScience
  
  Volume: ー Issue: 6 Pages: 101183-101183
- DOI
  10.1016/j.isci.2020.101183
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J10102, KAKENHI-PROJECT-20K06881, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K15919, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06531, KAKENHI-PUBLICLY-19H04912, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19H03313, KAKENHI-PROJECT-19H03536, KAKENHI-PROJECT-18K13371, KAKENHI-PLANNED-16H06528, KAKENHI-PROJECT-18H02538
[Journal Article] Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia2020
- Author(s)
  Masahito Sawahata, Daisuke Mori, Yuko Arioka, Hisako Kubo, Itaru Kushima, Kanako Kitagawa, Akira Sobue, Emiko Shishido, Mariko Sekiguchi, Akiko Kodama, Ryosuke Ikeda, Branko Aleksic, Hiroki Kimura, Kanako Ishizuka, Taku Nagai, Kozo Kaibuchi, Toshitaka Nabeshima, Kiyofumi Yamada, Norio Ozaki
- Journal Title
  
  Psychiatry and clinical neurosciences
  
  Volume: 1 Issue: 5 Pages: 1-10
- DOI
  10.1111/pcn.12993
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-19K08072, KAKENHI-PROJECT-18K19511, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H05090, KAKENHI-PROJECT-18K15513, KAKENHI-PROJECT-19K21221, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K16625, KAKENHI-PROJECT-18H04040
[Journal Article] Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway.2020
- Author(s)
  Lin, Y-H., Yamahashi, Y., Kuroda, K., Faruk M. O., Zhang, X., Yamada, K., Yamanaka, A., Nagai, T., Kaibuchi, K.
- Journal Title
  
  Neurocham. Int.
  
  Volume: 143 Pages: 104935-104935
- DOI
  10.1016/j.neuint.2020.104935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-18K14816, KAKENHI-PROJECT-19K16370, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H05016, KAKENHI-PUBLICLY-19H05209, KAKENHI-PUBLICLY-20H05061, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-19K23774
[Journal Article] Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice2020
- Author(s)
  Wulaer Bolati、Hada Kazuhiro、Sobue Akira、Itoh Norimichi、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 170-170
- DOI
  10.1186/s13041-020-00710-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-17H04252
[Journal Article] Reelin Supplementation Into the Hippocampus Rescues Abnormal Behavior in a Mouse Model of Neurodevelopmental Disorders2020
- Author(s)
  Ibi Daisuke、Nakasai Genki、Koide Nayu、Sawahata Masahito、Kohno Takao、Takaba Rika、Nagai Taku、Hattori Mitsuharu、Nabeshima Toshitaka、Yamada Kiyofumi、Hiramatsu Masayuki
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 14 Pages: 285-285
- DOI
  10.3389/fncel.2020.00285
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07332, KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-19K22504, KAKENHI-PROJECT-17H04252
[Journal Article] Methylation analysis for postpartum depression : a case control study.2019
- Author(s)
  Nakamura Y, Nakatochi M, Kunimoto S, Okada T, Aleksic B, Toyama M, Shiino T, Morikawa M, Yamauchi A, Yoshimi A, Furukawa-Hibi Y, Nagai T, Ohara M, Kubota C, Yamada K, Ando M, Ozaki N.
- Journal Title
  
  BMC Psychiatry.
  
  Volume: 19 Issue: 1 Pages: 190-199
- DOI
  10.1186/s12888-019-2172-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08306, KAKENHI-PROJECT-17K16375, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-16K10248, KAKENHI-PROJECT-17K16403
[Journal Article] Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons.2019
- Author(s)
  Zhang, X., Nagai, T., Ahammadm, R.D., Kuroda, K., Nakamuta, S., Nakano, T., Yukinawa, N., Funahashi, Y., Yamahashi, Y., Amano, M., Yoshimoto, J., Yamada, K., Kaibuchi, K.
- Journal Title
  
  Neurochem. Int.
  
  Volume: 122 Pages: 8-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02220
[Journal Article] Pharmacological and proteomic analyses of neonatal polyI:C-treated adult mice.2019
- Author(s)
  Kitagawa, K., Nagai, T., Yamada, K.
- Journal Title
  
  Neurosci. Res.
  
  Volume: 147 Pages: 39-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02220
[Journal Article] Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors2019
- Author(s)
  Funahashi Yasuhiro、Ariza Anthony、Emi Ryosuke、Xu Yifan、Shan Wei、Suzuki Ko、Kozawa Sachi、Ahammad Rijwan Uddin、Wu Mengya、Takano Tetsuya、Yura Yoshimitsu、Kuroda Keisuke、Nagai Taku、Amano Mutsuki、Yamada Kiyofumi、Kaibuchi Kozo
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 10 Pages: 3235-3252.e9
- DOI
  10.1016/j.celrep.2019.10.116
- NAID
  130007812598
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14816, KAKENHI-PROJECT-18K14849, KAKENHI-PUBLICLY-19H05209, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17J09461, KAKENHI-PROJECT-17K07383
[Journal Article] Proteomic analysis of lymphoblastoid cell lines from schizophrenic patients2019
- Author(s)
  Yoshimi A, Yamada S, Kunimoto S, Aleksic B, Hirakawa A, Ohashi MS, Matsumoto A, Hada K, Itoh N, Arioka Y, Kimura H, Kushima I, Nakamura Y, Shiino T, Mori D, Tanaka S, Hamada S, Noda Y, Nagai T, Yamada K, Ozaki N
- Journal Title
  
  Translational Psychiatry
  
  Volume: 9 Issue: 1 Pages: 126-126
- DOI
  10.1038/s41398-019-0461-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19511, KAKENHI-PROJECT-18H04040, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17K16403
[Journal Article] Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes.2018
- Author(s)
  A Sobue, N Ito, T Nagai, W Shan, K Hada, Nakajima A, Y Murakami, A Mouri, Y Yamamoto, T Nabeshima, K Saito, K Yamada
- Journal Title
  
  Glia
  
  Volume: 66 Issue: 5 Pages: 1034-52
- DOI
  10.1002/glia.23299
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-15H03086
[Journal Article] Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons2018
- Author(s)
  Zhang XJ, Nagai T, Ahammad RU, Kuroda K, Nakamuta S, Nakano T, Yukinawa N, Funahashi Y, Yamahashi Y, Amano M, Yoshimoto J, Yamada K, and Kaibuchi K.
- Journal Title
  
  Neurochemistry International
  
  Volume: 122 Pages: 8-18
- DOI
  10.1016/j.neuint.2018.10.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07383, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-17J10615, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-16K18393, KAKENHI-PROJECT-18K14816
[Journal Article] Pharmacological and proteomic analyses of neonatal polyI:C-treated adult mice.2018
- Author(s)
  Kitagawa, K., Nagai, T., Yamada, K.
- Journal Title
  
  Neurosci. Res.
  
  Volume: - Pages: 39-47
- DOI
  10.1016/j.neures.2018.10.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-17H04031
[Journal Article] Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia.2018
- Author(s)
  Sobue A, Kushima I, Nagai T, Shan W, Kohno T, Aleksic B, Aoyama Y, Mori D, Arioka Y, Kawano N, Yamamoto M, Hattori M, Nabeshima T, Yamada K, Ozaki N.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 13046-13046
- DOI
  10.1038/s41598-018-31390-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08281, KAKENHI-PROJECT-17K10295, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H03985, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-17K19500
[Journal Article] Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1Δ2-3/Δ2-3 mice2018
- Author(s)
  Wulaer B, Nagai T, Sobue A, Itoh N, Kuroda K, Kaibuchi K, Nabeshima T, Yamada K
- Journal Title
  
  Genes Brain Behav
  
  Volume: 印刷中 Issue: 8
- DOI
  10.1111/gbb.12478
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-18K14816, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-17K19483
[Journal Article] Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice2018
- Author(s)
  Bin Saifullah Md. Ali、Nagai Taku、Kuroda Keisuke、Wulaer Bolati、Nabeshima Toshitaka、Kaibuchi Kozo、Yamada Kiyofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 14413-14413
- DOI
  10.1038/s41598-018-32840-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14816, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-17K19483
[Journal Article] Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1Δ2-3/Δ2-3 mice.2018
- Author(s)
  Wulaer, B., Nagai T., Sobue, A., Itoh, N., Kuroda, K., Kaibuchi, K., Nabeshima, T., Yamada, K.
- Journal Title
  
  Gene Brain Behav.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19483
[Journal Article] Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.2018
- Author(s)
  Imai, K., Kotani, T., Tsuda, H., Nakano, T., Ushida, T., Iwase, A., Nagai T,, Toyokuni, S., Suzumura, A., Kikkawa, F.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 9221-9221
- DOI
  10.1038/s41598-018-27626-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17K19483
[Journal Article] Innate immune activation of astrocytes impairs neurodevelopment via upregulation of follistatin-like 1 and interferon-induced transmembrane protein 3.2018
- Author(s)
  Yamada, S., Itoh, N., Nagai, T., Nakai, T., Ibi, D., Nakajima, A., Nabeshima, T., Yamada, K.
- Journal Title
  
  J. Neuroinflammation.
  
  Volume: 15 Issue: 1 Pages: 295-295
- DOI
  10.1186/s12974-018-1332-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483
[Journal Article] Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1Δ2-3/Δ2-3 mice.2018
- Author(s)
  Wulaer, B., Nagai T., Sobue, A., Itoh, N., Kuroda, K., Kaibuchi, K., Nabeshima, T., Yamada, K.
- Journal Title
  
  Gene Brain Behav
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02220
[Journal Article] Association of impaired neuronal migration with cognitive deficits in extremely preterm infants.2017
- Author(s)
  Kubo, K.I., Deguchi, K., Nagai, T,, Ito, Y., Yoshida, K., Endo, T., Benner, S., Shan, W., Kitazawa, A., Aramaki, M., Ishii, K., Shin, M., Matsunaga, Y., Hayashi, K., Kakeyama, M., Tohyama, C., Tanaka, K.F., Tanaka, K., Takashima, S., Nakayama, M.
- Journal Title
  
  JCI Insight.
  
  Volume: 2 Issue: 10 Pages: 88609-88609
- DOI
  10.1172/jci.insight.88609
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19483, KAKENHI-PUBLICLY-16H01621, KAKENHI-PUBLICLY-17H06062, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-16H05361, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-15J08536, KAKENHI-PROJECT-15K09723, KAKENHI-PROJECT-15K18363
[Journal Article] Valocin-containing protein (VCP) is a novel IQ motif containing GTPase activating protein 1 (IQGAP1) interacting protein.2017
- Author(s)
  Itoh, N., Nagai, T,, Watanabe, T., Taki, K., Nabeshima, N., Kaibuchi, K., Yamada, K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 493 Issue: 4 Pages: 1384-1389
- DOI
  10.1016/j.bbrc.2017.09.159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19483, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080
[Journal Article] Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole-induced epilepsy through the induction of Homer1a.2017
- Author(s)
  2.Shan W, Nagai T, Tanaka M, Itoh N, Furukawa-Hibi Y, Nabeshima T, Sokabe M, Yamada K.
- Journal Title
  
  J Neurochem.
  
  Volume: - Issue: 1 Pages: 19-33
- DOI
  10.1111/jnc.14274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17K08306, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17K19483
[Journal Article] Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice2017
- Author(s)
  Konishi H, Ohgami N, Matsushita A, Kondo Y, Aoyama Y, Kobayashi M, Nagai T, Ugawa S, Yamada K, Kato M, Kiyama H
- Journal Title
  
  Neuroscience
  
  Volume: 印刷中 Pages: 15-23
- DOI
  10.1016/j.neuroscience.2017.03.028
- NAID
  120006331816
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-16K08343, KAKENHI-PROJECT-17K19483, KAKENHI-PUBLICLY-16H01639, KAKENHI-PROJECT-15H01743, KAKENHI-PROJECT-17H02220, KAKENHI-ORGANIZER-15H05935
[Journal Article] Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.2016
- Author(s)
  Aoyama Y, Toriumi K, Mouri A, Hattori T, Ueda E, Shimato A, Sakakibara N, Soh Y, Mamiya T, Nagai T, Kim HC, Hiramatsu M, Nabeshima T, Yamada K.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 41(2) Issue: 2 Pages: 578-89
- DOI
  10.1038/npp.2015.186
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08218, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26860175, KAKENHI-PROJECT-26293053
[Journal Article] Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo2016
- Author(s)
  Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, Nishi A, Kobayashi K, Yamada K, Amano M, Kaibuchi K
- Journal Title
  
  Neuron
  
  Volume: 89 (3) Issue: 3 Pages: 550-65
- DOI
  10.1016/j.neuron.2015.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06732, KAKENHI-PROJECT-15K06772, KAKENHI-PUBLICLY-15H01283, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-25560436, KAKENHI-PROJECT-25251021, KAKENHI-PROJECT-24220007
[Journal Article] Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: The role of Girdin in the CNS.2016
- Author(s)
  Itoh N, Enomoto A, Nagai T, Takahashi M, Yamada K
- Journal Title
  
  Rev Neurosci
  
  Volume: - Issue: 5 Pages: 481-490
- DOI
  10.1515/revneuro-2015-0072
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01284, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26221304
[Journal Article] Insular neural system controls decision-making in healthy and methamphetamine-treated rats2015
- Author(s)
  Mizoguchi H, Katahira K, Inutsuka A, Fukumoto K, Nakamura A, Wang T, Nagai T, Sato J, Sawada M, Ohira H,Yamanaka A, Yamada K
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 (29) Issue: 29 Pages: 3930-3939
- DOI
  10.1073/pnas.1418014112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640041, KAKENHI-PUBLICLY-15H01428, KAKENHI-PUBLICLY-26118506, KAKENHI-PUBLICLY-26118507, KAKENHI-PUBLICLY-26120713, KAKENHI-PROJECT-24243068, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-25460094, KAKENHI-PROJECT-26860157, KAKENHI-PROJECT-25284003, KAKENHI-PROJECT-26293046, KAKENHI-PROJECT-26293053
[Journal Article] FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization.2015
- Author(s)
  Udagawa, T., Fujioka, Y., Tanaka, M., Honda, D., Yokoi, S., Riku, Y., Ibi, D., Nagai, T., Yamada, K., Watanabe, H., Katsuno, M., Inada, T., Ohno, K., Sokabe, M., Okado, H., Ishigaki S*., and Sobue, G.
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 7098-7098
- DOI
  10.1038/ncomms8098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09310, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-26116003, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-24247028, KAKENHI-PROJECT-15H06719, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-15K15337, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-25860708, KAKENHI-PROJECT-26293206, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
[Journal Article] Stress increases DNA methylation of the neuronal PAS domain 4 (Npas4) gene.2015
- Author(s)
  Furukawa-Hibi Y, Nagai T, Yun J, Yamada K.
- Journal Title
  
  Neuroreport.
  
  Volume: 26 Issue: 14 Pages: 827-32
- DOI
  10.1097/wnr.0000000000000430
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-25460093
[Journal Article] Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD).2015
- Author(s)
  Nakajima, A., Aoyama, Y., Shin, E.J. Nam, Y., Kim, H.C. Nagai, T., Yokosuka, A., Mimaki, Y., Yokoi, T., Ohizumi, Y., Yamada, K.
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 289 Pages: 69-77
- DOI
  10.1016/j.bbr.2015.04.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26670121
[Journal Article] Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory.2015
- Author(s)
  Hori K, Nagai T, Shan W, Sakamoto A, Abe M, Yamazaki M, Sakimura K, Yamada K, Hoshino M.
- Journal Title
  
  PLoS One
  
  Volume: 30 Issue: 12 Pages: e0145979-e0145979
- DOI
  10.1371/journal.pone.0145979
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26350979, KAKENHI-PUBLICLY-15H01304, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24240048, KAKENHI-PROJECT-15H04268, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-15K14337, KAKENHI-PROJECT-24300138
[Journal Article] Noradrenergic refinement of glutamatergic neuronal circuits in the lateral superior olivary nucleus before hearing onset.2015
- Author(s)
  Hirao K, Eto K, Nakahata Y, Ishibashi H, Nagai T, Nabekura J.
- Journal Title
  
  J Neurophysiol.
  
  Volume: 114(3) Issue: 3 Pages: 1974-1986
- DOI
  10.1152/jn.00813.2014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21603, KAKENHI-PROJECT-15H03046, KAKENHI-PROJECT-14J30003, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26870826, KAKENHI-PROJECT-25253017
[Journal Article] Reelin has a preventive effect on phencyclidine-induced cognitive and sensory-motor gating deficits2015
- Author(s)
  Kazuhiro Ishii, Taku Nagai, Yuki Hirota, Mariko Noda, Toshitaka Nabeshima, Kiyofumi Yamada, Ken-ichiro Kubo, and Kazunori Nakajima
- Journal Title
  
  Neurosci. Res.
  
  Volume: 印刷中 Pages: 30-36
- DOI
  10.1016/j.neures.2014.12.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22111004, KAKENHI-PUBLICLY-25113525, KAKENHI-PUBLICLY-25123719, KAKENHI-PROJECT-25440114, KAKENHI-PROJECT-26430075, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-15H02355
[Journal Article] Induction of interferone-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes.2014
- Author(s)
  Nakajima A, Ibi D, Nagai T, Yamada S, Nabeshima T, Yamada K
- Journal Title
  
  Eur. J. Pharmacol.
  
  Volume: 745 Pages: 166-175
- DOI
  10.1016/j.ejphar.2014.08.034
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26670121
[Journal Article] Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence2014
- Author(s)
  Toriumi K., Kondo M., Nagai T., Furukawa-Hibi Y., Mamiya T., Fukushima T., Takeda M., Nitta A., Yamada K., Nabeshima T.(他7名)
- Journal Title
  
  Int. J . Neuropsychopharmacol
  
  Volume: 17 Pages: 443-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Alterations of GABAergic and dopaminergic system in mutant mice with disruption of exons 2 and 3 of the Disc1 gene.2014
- Author(s)
  Nakai T, Nagai T, Wang R, Yamada S, Kuroda K, Kaibuchi K, Yamada K
- Journal Title
  
  Neurochem. Int.
  
  Volume: 74 Pages: 74-83
- DOI
  10.1016/j.neuint.2014.06.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-25830051, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26670121
[Journal Article] Girdin phosphorylation is crucial for synaptic plasticity and memory: A potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor2014
- Author(s)
  Tsuyoshi Nakai, Taku Nagai, Motoki Tanaka, Norimichi Itoh, Naoya Asai, Atsushi Enomoto, Masato Asai, Shinnnosuke Yamada, Ali Bin Saifullah, Masahiro Sokabe, Masahide Takahashi, Kiyofumi Yamada
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 34 Issue: 45 Pages: 14995-15008
- DOI
  10.1523/jneurosci.2228-14.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-25460493
[Journal Article] Matrix metalloproteinase-3 is a possible mediator of neurodevelopmental impairment due to polyl : C-induced innate immune activation of astrocytes2014
- Author(s)
  S Yamada, T Nagai, T Nakai, D Ibi, A Nakajima, K Yamada
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 38 Pages: 272-282
- DOI
  10.1016/j.bbi.2014.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-13J03699, KAKENHI-PUBLICLY-24111518, KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-25460093
[Journal Article] SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization2014
- Author(s)
  K Toriumi, M Ikami, M Kondo, A Mouri, T Koseki, D Ibi, Y Furukawa-Hibi, T Nagai, T Mamiya, A Nitta, K Yamada and T Nabeshima
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 91 Issue: 12 Pages: 1525-1532
- DOI
  10.1002/jnr.23273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24590304
[Journal Article] Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence2014
- Author(s)
  Toriumi K, Kondo M, Nagai T, Hashimoto R, Ohi K, Song Z, Tanaka J, Mouri A, Koseki T, Yamamori H, Furukawa-Hibi Y, Mamiya T, Fukushima T, Takeda M, Nitta A, Yamada K, Nabeshima T
- Journal Title
  
  Int J Neuropsychopharmacol
  
  Volume: 17 Issue: 03 Pages: 443-453
- DOI
  10.1017/s1461145713001302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24590304, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25461730, KAKENHI-PROJECT-26460095
[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013
- Author(s)
  D Ibi, I Nagai, A Nakajima, H Mizoguchi, T Kawase, D Tsuboi, S Kano, Y Sato, M Hayakawa, U. C. Lange, D. J. Adams, M. Azim Surani, T Satoh, A Sawa, K Kaibuchi, T Nabeshima and K Yamada
- Journal Title
  
  Glia
  
  Volume: 61 Issue: 5 Pages: 679-693
- DOI
  10.1002/glia.22461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23591594, KAKENHI-PROJECT-23790290, KAKENHI-PROJECT-23791220, KAKENHI-PUBLICLY-24111518, KAKENHI-PROJECT-24657140
[Journal Article] Neuronal PAS domain protein 4 (Npas4) regulates neurite outgrowth and phosphorylation of synapsin I2013
- Author(s)
  Yun, J., Nagai, T., Furukawa-Hibi, Y., Kuroda, K., Kaibuchi, K., Greenberg, M.E., Yamada, K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Pages: 2655-2664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization2013
- Author(s)
  Toriumi K., Ikami M., Furukawa-Hibi Y., Nagai T., Mamiya T., Nitta A., Yamada K. and Nabeshima T.(他3名)
- Journal Title
  
  J . Neurosci. Res
  
  Volume: 91 Pages: 1525-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013
- Author(s)
  Ibi, D., Nagai, T., Nakajima, A., Mizoguchi, H., Kawase, T., Tsuboi, D., Kano, S.I., Sato, Y., Hayakawa, M., Lange, U.C., Adams, D.J., Surani, M.A., Satoh, T., Sawa, A., Kaibuchi, K., Nabeshima, T., Yamada, K
- Journal Title
  
  Glia
  
  Volume: 61 Pages: 679-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Neuronal PAS domain protein 4 (Npas4) regulates neurite outgrowth and phosphorylation of synapsin I2013
- Author(s)
  Yun, J., Nagai, T., Furukawa-Hibi, Y., Kuroda, K., Kaibuchi, K. and Yamada, K.
- Journal Title
  
  J . Biol. Chem
  
  Volume: 288 Pages: 2655-2664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Animal models of schizophrenia for molecular and pharmacological intervention and potential candidate molecules.2013
- Author(s)
  Mouri, T Nagai, D Ibi, K Yamada.
- Journal Title
  
  Neurobiol. Dis.
  
  Volume: 53 Pages: 61-74
- DOI
  10.1016/j.nbd.2012.10.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23791325
[Journal Article] Neuronal PAS domain domain protein 4 (Npas4) regulates neurite outgrowth and phosphorylation of synapsin I.2013
- Author(s)
  Yun J, Nagai T, Furukawa-Hibi Y, Kuroda K, Kaibuchi K, Greenberg ME, and Yamada K
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 4 Pages: 2655-2664
- DOI
  10.1074/jbc.m112.413310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23659135, KAKENHI-PROJECT-23790081, KAKENHI-PROJECT-25830051
[Journal Article] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter2012
- Author(s)
  Furukawa-Hibi, Y., Yun, J., Nagai, T. and Yamada, K.
- Journal Title
  
  J . Neurochem
  
  Volume: 123 Pages: 866-875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter2012
- Author(s)
  Furukawa-Hibi Y, Yun J, Nagai T, and Yamada K
- Journal Title
  
  J Neurochem
  
  Volume: 123 Issue: 5 Pages: 866-875
- DOI
  10.1111/jnc.12034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23790081
[Journal Article] Placental extract improves hippocampal neuronal loss and fear memory impairment resulting from chronic restraint stress in ovariectomized mice2012
- Author(s)
  Takuma, K., Mizoguchi, H., Funatsu, Y., Kitahara, Y., Ibi, D., Kamei, H., Matsuda, T., Koike, K., Inoue, M., Nagai, T., Yamada, K
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 120 Pages: 89-97
- NAID
  10031123550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Combination of chronic stress and ovariectomy causes conditioned fear memory deficits and hippocampal cholinergic neuronal loss in mice2012
- Author(s)
  Takuma, K., Mizoguchi, H., Funatsu, Y., Hoshina, Y., Himeno, Y., Fukuzaki, E., Kitahara, Y., Arai, S., Ibi, D., Kamei, H., Matsuda, T., Koike, K., Inoue, M., Nagai, T., Yamada, K
- Journal Title
  
  Neuroscience
  
  Volume: 207 Pages: 261-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Prenatal NMDA Receptor Antagonism Impaired Proliferation of Neuronal Progenitor, Leading to Fewer Glutamatergic Neurons in the Prefrontal Cortex2012
- Author(s)
  Toriumi K, et al
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: (In press) Issue: 6 Pages: 1387-1396
- DOI
  10.1038/npp.2011.324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213, KAKENHI-PROJECT-23790081, KAKENHI-PROJECT-23791325, KAKENHI-PROJECT-24590304, KAKENHI-PROJECT-24650433
[Journal Article] D-Serine Ameliorates Neonatal PolyI:C Treatment–Induced Emotional and Cognitive Impairments in Adult Mice2012
- Author(s)
  Nagai T, Yu J, Kitahara Y, Nabeshima T and Yamada K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 120 Issue: 3 Pages: 213-227
- DOI
  10.1254/jphs.12142FP
- NAID
  10031147568
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23659135
[Journal Article] ストレスにより誘発される脳機能障害とストレス応答性転写因子Npas4の機能解析2012
- Author(s)
  永井拓, 尹在錫, 衣斐大祐, 小池宏幸, 日比陽子, 山田清文
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 139 Pages: 147-151
- NAID
  10030572362
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex2012
- Author(s)
  Toriumi, K., Mouri, A., Narusawa, S., Aoyama, Y., Ikawa, N., Lu, L., Nagai, T., Mamiya, T., Kim, H.C., Nabeshima, T
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 37 Pages: 1387-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] D-serine ameliorates neonatal polyI:C treatment-induced emotional and cognitive impairments in adult mice2012
- Author(s)
  Nagai, T., Yu, J., Kitahara, Y., Nabeshima T., Yamada, K
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 120 Pages: 213-227
- NAID
  10031147568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter2012
- Author(s)
  Furukawa-Hibi, Y., Yun, J., Nagai, T., Yamada, K
- Journal Title
  
  J. Neurochem
  
  Volume: 123 Pages: 866-875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Effects of sub-acute and sub-chronic inhalation of 1-bromopropane on neurogenesis in adult rats2012
- Author(s)
  Zhang, L., Nagai, T., Yamada, K., Ibi, D., Ichihara, S., Subramanian, K., Huang, Z., Mohideen, S.S., Naito, H., Ichihara G
- Journal Title
  
  Toxicology
  
  Volume: 304C Pages: 76-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Behavioral alterations associated with targeted disruption of exons 2 and 3 of the DISC1 gene in the mouse2011
- Author(s)
  Kuroda, K., Yamada, S., Tanaka, M., Iizuka, M., Yano, H., Mori, D., Tsuboi, D., Nishioka, T., Namba, T., Iizuka, Y., Kubota, S., Nagai, T., Ibi, D., Wang, R., Enomoto, A., Isotani-Sakakibara,M., Asai, N., Kimura, K., Kiyonari, H., Abe, T., Mizoguchi, A., Sokabe, M., Takahashi, M., Yamada, K., Kaibuchi, K
- Journal Title
  
  Hum. Mol. Genet
  
  Volume: 20 Pages: 4666-4683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment2011
- Author(s)
  Nagai, T., Kitahara, Y., Ibi, D., Nabeshima, T., Sawa, A., Yamada, K
- Journal Title
  
  Behav. Brain Res
  
  Volume: 225 Pages: 305-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice.2011
- Author(s)
  Furukawa-Hibi, Y., Alkam T., Nitta, A., Matsuyama, A., Mizoguchi, H., Suzuki, K., Moussaoui, S., Yu, Q-S., Greig, N., Nagai, T. and Yamada, K.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Animal model for schizophrenia that reflects gene-environment interactions2011
- Author(s)
  Taku Nagai, et al
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 34 Pages: 1364-1368
- NAID
  130001872425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046
[Journal Article] Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice.2011
- Author(s)
  Furukawa-Hibi, Y, Alkam, T., Nitta, A., Matsuyama, A., Mizoguchi, H., Suzuki, K., Moussaoui, S., Yu, Q-S., Greig, N.H., Nagai, T., Yamada, K.
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 225 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-βpeptide in mice2011
- Author(s)
  Furukawa-Hibi, Y., Alkam T., Nitta, A., Nagai, T. and Yamada, K.(他6名)
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment2011
- Author(s)
  Nagai T, Kitahara Y, Ibi D, Nabeshima T, Sawa A and Yamada K
- Journal Title
  
  Behav Brain Res
  
  Volume: 225 Issue: 1 Pages: 305-310
- DOI
  10.1016/j.bbr.2011.07.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046
[Journal Article] Exposure to enriched environments during adolescence prevents abnormal behaviours associated with histone deacetylation in phencyclidine-treated mice2011
- Author(s)
  Koseki, T., Mouri, A., Mamiya, T., Aoyama, Y., Toriumi, K., Suzuki, S., Nakajima, A., Yamada, T., Nagai, T., Nabeshima, T
- Journal Title
  
  Int. J. Neuropsychopharmacol
  
  Volume: 18 Pages: 1-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment.2011
- Author(s)
  Nagai, T., Kitahara, Y., Ibi, D., Nabeshima, T., Sawa, A., Yamada, K.
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 225 Pages: 305-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Exposure to enriched environments during adolescence prevents abnormal behaviours associated with histone deacetylation in phencyclidine-treated mice.2011
- Author(s)
  Koseki, T., Mouri, A., Mamiya, T., Aoyama, Y., Toriumi, K., Suzuki, S., Nakajima, A., Yamada, T., Nagai, T., Nabeshima, T.
- Journal Title
  
  Int. J. Neuropsychopharmacol.
  
  Volume: 18 Pages: 1-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790081
[Journal Article] Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice2010
- Author(s)
  Yun, J., Koike, H., Ibi, D., Toth, E., Mizoguchi, H., Nitta, A., Yoneyama, M., Ogita, K.Yoneda, Y., Nabeshima, T., Nagai, T., Yamada, K.
- Journal Title
  
  Possible involvement of a brain-specific transcription factor Npas4.J.Neurochem 114
  
  Pages: 1840-1851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790067
[Journal Article] Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice : possible involvement of abrain-specific transcription factor Npas4.2010
- Author(s)
  Yun J, Nagai T, Nabeshima T., et al
- Journal Title
  
  J Neurochem. 114(6)
  
  Pages: 1840-1851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Nicotine ameliorates emotional and cognitive impairments induced by neonatal polyI2010
- Author(s)
  Yu, J., Nagai, T., Ibi, D., Kitahara, Y., Nabeshima, T., Yamada, K.
- Journal Title
  
  C treatment in mice.Open Behav.Sci.J. 4
  
  Pages: 9-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790067
[Journal Article]2010
- Author(s)
  永井拓, 鍋島俊隆, 山田清文
- Journal Title
  
  実践行動薬理学(第II編応用編:行動薬理研究の現在、第4章報酬機構関連、3. 依存性薬物による精神障害の分子機序)(金芳堂)
  
  Pages: 272-281
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Dysfunction of dopamine release in the prefrontal cortex of dysbindin deficient sandy mice : An in vivo microdialysis study2010
- Author(s)
  Nagai T, et al.
- Journal Title
  
  Neurosci.Lett. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Prenatal exposure to phencyclidine produces abnormal behaviour and NMDA receptor expression in postpubertal mice.2010
- Author(s)
  Lu L, Mamiya T, Toriumi K, Mouri A, Nagai T, Nabeshima T.
- Journal Title
  
  Int J Neuropsychopharmacol. 13(7)
  
  Pages: 877-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Dysfunction of dopamine release in the prefrontal cortex of dysbindin deficient sandy mice : an in vivo microdialysis study.2010
- Author(s)
  Nagai T, et al.
- Journal Title
  
  Neurosci. Lett. 470
  
  Pages: 134-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790067
[Journal Article] Dysfunction of dopamine release in the prefrontal cortex of dysbindin deficient sandy mice2010
- Author(s)
  Nagai, T., Kitahara, Y., Shiraki, A., Hikita, T., Taya, S., Kaibuchi, K., Yamada, K.
- Journal Title
  
  an in vivo microdialysis study.Neurosci.Lett 470
  
  Pages: 134-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790067
[Journal Article] Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice : a possible involvement of a brain specific transcription factor Npas4.2010
- Author(s)
  Yun J, Koike H, Ibi D, Toth E, Mizoguchi H, Nitta A, Yoneyama M, Ogita K, Yoneda Y, Nabeshima T, Nagai T, Yamada K
- Journal Title
  
  J.Neurochem 114
  
  Pages: 1840-1851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Dysfunction of dopamine release in the prefrontal cortex of dysbindin deficient sandy mice : an in vivo microdialysis study.2010
- Author(s)
  Nagai T, et al.
- Journal Title
  
  Neurosci.Lett.
  
  Volume: 470 Pages: 134-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790067
[Journal Article] Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.2009
- Author(s)
  Ibi D, Nagai T, Kitahara Y, Mizoguchi H, Koike H, Shiraki A, Takuma K, Kamei H, Noda N, Nitta A, Nabeshima T, Yoneda Y, Yamada K
- Journal Title
  
  Neurosci.Res. 64
  
  Pages: 297-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors.2009
- Author(s)
  Nagai, T., Murai, R., Matsui, K., Kamei, H., Noda, Y., Furukawa, H., Nabeshima, T.
- Journal Title
  
  Psychopharmacology 202
  
  Pages: 315-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790067
[Journal Article] Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D_1 and serotonin 5-HT_<1A> receptors2009
- Author(s)
  Nagai, et.al.
- Journal Title
  
  Psychopharmacology 202
  
  Pages: 315-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790053
[Journal Article] Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D^1 and serotonin 5-HT^1A receptors2009
- Author(s)
  Nagai, T., Murai, R., Matsui, K., Kamei, H., Noda, Y., Furukawa, H. and Nabeshima, T
- Journal Title
  
  Psychopharmacology 202
  
  Pages: 315-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790053
[Journal Article] Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors.2009
- Author(s)
  Nagai T, et al.
- Journal Title
  
  Psychopharmacology(Berl) 202
  
  Pages: 315-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine and 5-HT1A receptors.2009
- Author(s)
  Nagai T, Nabeshima T.
- Journal Title
  
  Psychopharmacology. 202
  
  Pages: 315-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Therapeutic potential of nicotine for methamphetamine-induced impairment of sensorimotor gating : involvement of pallidotegmental neurons.2009
- Author(s)
  Mizoguchi H, Nagai T, Nabeshima T., et al
- Journal Title
  
  Psychopharmacology. 207
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] The long-lasting effects of cross-fostering on the emotional behavior in ICR mice.2009
- Author(s)
  Lu L, Mamiya T, Lu P, Niwa M, Mouri A, Nagai T, Nabeshima T.
- Journal Title
  
  Behav Brain Res. 198
  
  Pages: 172-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Aripiprazole ameliorates phencyclidine- induced impairment of recognition memory through dopamine D_1 and serotonin 5-HT_<1A> receptors.2009
- Author(s)
  Nagai T, et al.
- Journal Title
  
  Psychopharmacology 202
  
  Pages: 315-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790067
[Journal Article] Basic and translational research on proteinase-activated receptors : Regulation of nicotine reward by the tissue plasminogen activator (tPA)- plasmin system via proteinase-activated receptor 12008
- Author(s)
  Nagai, et al.
- Journal Title
  
  J. Pharmacol. Sci. 108
  
  Pages: 408-414
- NAID
  10025732467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Basic and translational research on proteinase-activated receptors : Regulation of nicotine reward by the tissue plasminogen activator (tPA)-plasmin system via proteinase-activated receptor 12008
- Author(s)
  Nagai T, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Sci. 108
  
  Pages: 408-414
- NAID
  10025732467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.2008
- Author(s)
  Fukakusa, A., Nagai, T., Mizoguchi, H., Otsuka, N., Kimura, H., Kamei, H., Kim, H-C., Nabeshima, T., Takuma, K. and Yamada, K
- Journal Title
  
  J. Neurochem 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790053
[Journal Article] Basic and translational research on proteinase-activated receptors : Regulation of nicotine reward by the tissue plasminogen activator (tPA)-plasmin system via proteinase-activated receptor 1.2008
- Author(s)
  Nagai T, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Sci. 108
  
  Pages: 408-414
- NAID
  10025732467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Involvement of Involvement of pallidotegmental neurons in methamphetamine-and MK-801-induced impairment of prepulse inhibition of the acoustic startle reflex in mice: reversal by GABAB receptor agonist baclofen.2008
- Author(s)
  Arai S, Nagai T, Nabeshima T, Yamada K.
- Journal Title
  
  Neuropsychopharmacology. 33(13)
  
  Pages: 3164-3175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice.2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Social isolation Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice.2008
- Author(s)
  Ibi D, Nagai T, Nabeshima T, Yamada K.
- Journal Title
  
  J Neurochem. 105(3)
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.2008
- Author(s)
  Fukakusa A, Nagai T, Nabeshima T., et al
- Journal Title
  
  J Neurochem. 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390073
[Journal Article] Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system2007
- Author(s)
  Ito, M., Nagai, T., Mizoguchi, H., Fukakusa, A, Nakanishi, Y., Kamei, H., Nabeshima, T.,Takuma, K. and Yamada, K
- Journal Title
  
  J. Neurochem 101
  
  Pages: 1392-1399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790053
[Journal Article] Ginkgo biloba extract EGb761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats.2007
- Author(s)
  Takuma K, Hoshina, Y, Arai S, Himeno Y, Matsuo, A, Funatsu Y, Kitahara Y, Ibi, D, Hayase M, Kamei H, Mizoguchi H, Nagai T, Koike K, Inoue M, Yamada K
- Journal Title
  
  Neuroscience 149
  
  Pages: 256-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex.2007
- Author(s)
  NAGAI, Taku
- Journal Title
  
  Lerrning ＆ Memory 14・3
  
  Pages: 117-125
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] Ito, M., Nagai, T., Mizoguchi, H., Sato, K., Hayase, M., Otsuka, N., Fukakusa, A., Kumagai, N., Kim2007
- Author(s)
  Ito, M., Nagai, T., Mizoguchi, H., Sato, K., Hayase, M., Otsuka, N., Fukakusa, A., Kumagai, N., Kim
- Journal Title
  
  J. Neurochem 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790053
[Journal Article] Activation of post-synaptic dopamine D1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling.2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol2007
- Author(s)
  Nagai, T., Takuma, K., Dohniwa, M., Ibi, D., Mizoguchi, H., Kamei, H., Nabeshima, T.and Yamada, K
- Journal Title
  
  Psychopharmacology 194
  
  Pages: 21-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790053
[Journal Article] Activation of post-synaptic dopamine D_1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Repeated methamphetamine treatment impairs spatial working memory inrats: reversal by clozapine but not haloperidol2007
- Author(s)
  Nagai, et. al.
- Journal Title
  
  Psychopharmacology 194
  
  Pages: 21-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790053
[Journal Article] The rewards of nicotine : regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1.2006
- Author(s)
  Nagai T et al.
- Journal Title
  
  J. Neurosci. 26・47
  
  Pages: 12374-12383
- Data Source
  KAKENHI-PROJECT-17790056
[Journal Article] モルヒネ依存形成における組織プラスミノーゲン活性化因子の役割2006
- Author(s)
  永井拓ら
- Journal Title
  
  日本アルコール薬物医学会雑誌 41・1
  
  Pages: 23-30
- NAID
  10016687450
- Data Source
  KAKENHI-PROJECT-17790056
[Journal Article] Involvement of hippocampal extracellular signal-regulated kinase 1/2 in spatial working memory in rats.2006
- Author(s)
  Nagai T et al.
- Journal Title
  
  Neuroreport. 17・13
  
  Pages: 1453-1457
- Data Source
  KAKENHI-PROJECT-17790056
[Journal Article] Modification by the tissue plasminogen activator-plasmin system of morphine-induced dopamine release and hyperlocomotion, but not anti-nociceptive effect in mice2005
- Author(s)
  Nagai T et al.
- Journal Title
  
  J.Neurochem. 93・5
  
  Pages: 1272-1279
- Data Source
  KAKENHI-PROJECT-17790056
[Journal Article] 脳と組織プラスミノーゲン活性化因子2005
- Author(s)
  永井拓ら
- Journal Title
  
  脳21 8・4
  
  Pages: 437-442
- Data Source
  KAKENHI-PROJECT-17790056
[Patent] 統合失調症マーカー及びその利用2010
- Inventor(s)
  尾崎紀夫, 永井拓, 吉見陽,山田真之亮
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2010-147017
- Filing Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-21790067
[Patent] 統合失調症マーカー及びその利用2010
- Inventor(s)
  尾崎紀夫, 永井拓, 吉見陽, 山田真之亮
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Number
  2010-147017
- Filing Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] Comprehensive phosphoproteomic analysis in reelin mutant mice identified an important role of twinfilin 1 in spine development and actin dynamics.2023
- Author(s)
  Geyao Dong, Norimichi Itoh, Takaaki Matsui, Ayato　Sato, Tetsuo Matsuzaki, Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  The 34th CINP World Congress of Neuropsychopharmacology (CINP2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] Twinfilin 1 Phosphorylation is Crucial For Reelin Signaling In The Regulation Of Spine Morphology And Cognitive Function2023
- Author(s)
  Kiyofumi Yamada, Geyao Dong, Norimichi Itoh, Takaaki Matsui, Ayato Sato,Tetsuo Matsuzaki , Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai, Norio Ozaki, Toshitaka Nabeshima
- Organizer
  The 34th CINP World Congress of Neuropsychopharmacology (CINP2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] 知ってそうで知らなかった精神神経薬：ドパミンの働きと抗精神病薬の使い方.2022
- Author(s)
  永井拓
- Organizer
  第96回日本薬理学会年会／第43回日本臨床薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] Arhgap10遺伝子変異マウスの神経活動の解析にむけたin vivoカルシウムイメージング法の確立2022
- Author(s)
  田中里奈子、羽田和弘、溝口博之、澤幡雅仁、永井拓、森大輔、鍋島俊隆、貝淵弘三、尾崎紀夫、山田清文
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] PKA-Rap1 pathway in the nucleus accumbens regulates emotional behaviors of mice.2022
- Author(s)
  Nagai T.
- Organizer
  The 1st Fujita International Symposium on Brain Science.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] オピオイド受容体拮抗薬を配合した乱用抵抗性製剤の効果に関する薬理学的検討.2022
- Author(s)
  永井拓, 張心健, 山田清文
- Organizer
  第57回日本アルコール・アディクション医学会学術総会（アルコール・薬物依存関連学会　合同学術総会）
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] Phosphorylated twinfilin1 plays a major role in dendritic spine development, but not brain layer formation2022
- Author(s)
  Geyao Dong, Norimichi Itoh, Tetsuo Matsuzaki, Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai,Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Phosphorylation of twinfilin-1 involved in the reelin signaling plays a crucial role in spine development2022
- Author(s)
  Geyao Dong, Norimichi Itoh, Hiroyuki Mizoguchi , Tetsuo Matsuzaki, Daisuke Mori, Taku Nagai, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  JPW2022
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway.2022
- Author(s)
  Nagai T, Lin Y-H, Yamahashi Y, Kuroda K, Faruk MO, Zhang X, Kaibuchi K.
- Organizer
  4th Japan-UK Neuroscience Symposium 2022.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] Development of ADAMTS-3 Knockdown Method for Enhancement of Reelin Signaling in vitro.2021
- Author(s)
  Yumi Tsuneura, Masahito Sawahata, Norimichi Ito, Takao Kohno, Mitsuharu Hattori, Taku Nagai, Kiyofumi Yamada.
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] 快・不快を生み出す脳内分子メカニズム2021
- Author(s)
  永井拓
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] 情動行動の発現に関与する脳内シグナル伝達機構2021
- Author(s)
  永井拓
- Organizer
  2021年度生理学研究所研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] 情動行動とタンパク質リン酸化2021
- Author(s)
  永井拓
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] MK-801処置マウスの統合失調症様行動及び側坐核における神経伝達物質遊離に対するRhoキナーゼ阻害剤ファスジルの効果2021
- Author(s)
  田中里奈子、澤幡雅仁、高瀨冴子、Liu Yue、羽田和弘、溝口博之、永井拓、鍋島俊隆、尾崎紀夫、山田清文
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] The Mice Carrying Schizopherenia-associated Mutation of Arhgap10 Gene are Vulnerable to Psychostimulants: Association with Morphological Abnormalities in Striatal Neurons.2021
- Author(s)
  Kiyofumi Yamada, Kazuhiro Hada, Taku Nagai
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] コカインにより惹起されるリン酸化シグナルの解明2021
- Author(s)
  永井拓
- Organizer
  2021年度アルコール・薬物依存関連学会合同学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] The Mice Carrying Schizopherenia-associated Mutation of Arhgap10 Gene are Vulnerable to Psychostimulants:Association with Morphological Abnormalities in Striatal Neurons.2021
- Author(s)
  Kiyofumi Yamada, Kazuhiro Hada, Taku Nagai
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Comprehensive Phosphoproteomic Analysis in Reelin Mutant Mice Revealed a Crucial Role of Twinfilin-1 in Spine Development.2021
- Author(s)
  Norimichi Ito, Takaaki Matsui, Ayato sato, Kazuhiro Hada, Yumi Tsuneura, Taku Nagai, Toshitaka Nabeshima, Kiyofumi Yamada
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Comprehensive Phosphoprotemic Analysis in Reelin Mutant Mice Revealed a Crucial Rolr of Twinfilin-1 in Spine Development.2021
- Author(s)
  Norimichi Ito、Takaaki Matsui、Ayato sato、Kazuhiro Hada、Yumi Tsuneura、Taku Nagai、Toshitaka Nabeshima、Kiyofumi Yamada
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] 情動行動を司る細胞内シグナルの探索2020
- Author(s)
  永井拓.
- Organizer
  第68回脳の医学・生物学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] 統合失調症の克服に向けた薬理学的アプローチ2020
- Author(s)
  永井拓.
- Organizer
  第93回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] 次世代を担う若き医療薬科学研究者達へ繋ぐバトン：恩師からのメッセージ2020
- Author(s)
  永井拓
- Organizer
  第14回次世代を担う若手のための医療薬科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] 客観的な診断に基づく統合失調症の新規治療法の開発2020
- Author(s)
  永井拓, 尾崎紀夫, 山田清文.
- Organizer
  第30回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] 精神疾患の新規薬物療法を目指したリバーストランスレーショナルリサーチ2020
- Author(s)
  永井拓
- Organizer
  第41回日本臨床薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07082
[Presentation] Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors2020
- Author(s)
  Yasuhiro Funahashi, Anthony Ariza, Ryosuke Emi, Yifan Xu, Shan Wei, Ko Suzuki, Sachi Kozawa, Rijwan Uddin Ahammad, Mengya Wu, Tetsuya Takano, Yoshimitsu Yura, Keisuke Kuroda, Taku Nagai, Mutsuki Amano, Kiyofumi Yamada、 Kozo Kaibuchi
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] プロテインキナーゼAの抑制は、脳の報酬系に影響を与える2020
- Author(s)
  許伊凡、船橋靖広、永井拓、貝淵弘三
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] MAPKによるNpas4リン酸化は報酬関連の遺伝子発現と行動を制御する2020
- Author(s)
  船橋靖広、Anthony Ariza, 恵美亮佑、伊許凡、偉単、鈴木航、小澤祥、Rijwan Uddin Ahammad、呉夢雅、高野哲也、由良義光、黒田啓介、永井拓、天野睦紀、山田清文、貝淵弘三
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] KANPHOS (Kinase-Associated Phospho-Signaling) Platform - A comprehensive database for kinase-associated neural phosphorylation signaling"2019
- Author(s)
  Keisuke Kuroda, Mutsuki Amano, Junichiro Yoshimoto, Taku Nagai, Takayuki Kannon, Tomoki Nishioka, Shiro Usui, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] 快・不快情動の細胞内シグナル2019
- Author(s)
  永井拓
- Organizer
  第49回日本神経精神薬理学会・第29回日本臨床神経精神薬理学会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Suppressed dopamine release caused by aversive stimulus activates PKA-Rap1 signaling in accumbal D2R-medium spiny neuron2019
- Author(s)
  You-Hsin Lin, Taku Nagai, Yukie Yamahashi, Keisuke Kuroda, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] The mode of action of acetylcholine in nucleus accumbens that leads to aversive learning2019
- Author(s)
  Yukie Yamahashi, Sho Iwanaga, Yuya Tokumoto, You-Hsin Lin, Xijian Zhang, Taku Nagai, Daisuke Tsuboi, Kozo Kaibuchi
- Organizer
  第３４回日本大脳基底核研究会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] Striatal phosphorylation signals regulating reward and aversive behaviors. (Symposium).2019
- Author(s)
  Nagai T.
- Organizer
  The 22nd Japan-Korea Joint Seminar on Pharmacology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] ゲノムのコピー数変化から統合失調症の診断治療標的を探る. (シンポジウム).2019
- Author(s)
  永井拓, 尾崎紀夫, 山田清文.
- Organizer
  第92回日本薬理学会年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons2019
- Author(s)
  Xinjian Zhang, Taku Nagai, Ahammad Rijwan Uddin, Keisuke Kuroda, Takashi Nakano, Junichiro Yoshimoto, Kiyofumi Yamada, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] Phosphoroteomic analysis in orleans reeler mice identified TWF1 as a novel reelin-associated phosphorylation signal.2019
- Author(s)
  Nagai Taku, Matsui Takaaki, Sato Ayato, Itoh, Norimichi, Yamada Kiyofumi.
- Organizer
  NEURO2019 第42回日本神経科学大会　第62回日本神経化学大会
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Striatal phosphorylation signals regulating reward and aversive behaviors. (Symposium).2019
- Author(s)
  Nagai T.
- Organizer
  The 22nd Japan-Korea Joint Seminar on Pharmacology.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] ゲノムのコピー数変化から統合失調症の診断治療標的を探る. (シンポジウム).2019
- Author(s)
  永井拓, 尾崎紀夫, 山田清文.
- Organizer
  第92回日本薬理学会年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Dopamine and adenosine signaling pathways are analyzed in striatal medium spiny neurons using kinase-associated neural phospho-signaling (KANPHOS) database2019
- Author(s)
  Xinjian Zhang, Taku Nagai, Keisuke Kuroda, Kozo Kaibuchi
- Organizer
  Neuroscience2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] The mode of action of acetylcholine in nucleus accumbens that leads to aversive learning2019
- Author(s)
  Yukie Yamahashi, Sho Iwanaga, Yuya Tokumoto, You-Hsin Lin, Xijian Zhang, Taku Nagai, Daisuke Tsuboi, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors2019
- Author(s)
  Yasuhiro Funahashi, Anthony Ariza, Ryosuke Emi, Yifan Xu, Shan Wei, Ko Suzuki, Sachi Kozawa, Tetsuya Takano, Yoshimitsu Yura, Keisuke Kuroda, Taku Nagai, Mutsuki Amano, Kiyofumi Yamada, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] 統合失調症患者から同定されたReelin遺伝子変異の病態生理学的意義. (シンポジウム).2018
- Author(s)
  永井拓, 祖父江顕, 久島周, 尾崎紀夫, 山田清文.
- Organizer
  第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] 自然免疫系の過剰な活性化はアストロサイト由来主要組織適合抗原I型を介して異常行動を引き起こす. (シンポジウム).2018
- Author(s)
  永井拓, 祖父江顕, 山田清文.
- Organizer
  第34回日本ストレス学会学術総会.
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] ホメオスタシスの観点から考えるてんかん治療の標的分子.2018
- Author(s)
  永井拓, Shan Wei, 山田清文.
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Npas4-Homer1a pathway regulates neuronal homeostasis in animal model of epilepsy.2018
- Author(s)
  Nagai, T., Shan, W., Tanaka, M., Itoh, N., Furukawa-Hibi, Y., Nabeshima, T., Sokabe, M., Yamada, K.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] 統合失調症の克服を目指したリバーストランスレーショナルリサーチ. (シンポジウム).2018
- Author(s)
  永井拓, 尾崎紀夫, 山田清文.
- Organizer
  第28回日本医療薬学会年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] Npas4-Homer1a pathway regulates neuronal homeostasis in animal model of epilepsy.2018
- Author(s)
  Nagai, T., Shan, W., Tanaka, M., Itoh, N., Furukawa-Hibi, Y., Nabeshima, T., Sokabe, M., Yamada, K.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Role of striatal phosphorylation signaling in emotional behaviors. (ワークショップ).2018
- Author(s)
  永井拓, 貝淵弘三.
- Organizer
  第41回日本分子生物学会年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] ホメオスタシスの観点から考えるてんかん治療の標的分子.2018
- Author(s)
  永井拓, Shan Wei, 山田清文.
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] ホメオスタシスの観点から考えるてんかん治療の標的分子. (シンポジウム).2018
- Author(s)
  永井拓, Shan Wei, 山田清文.
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] 統合失調症患者から同定されたReelin遺伝子変異の病態生理学的意義. (シンポジウム).2018
- Author(s)
  永井拓, 祖父江顕, 久島周, 尾崎紀夫, 山田清文.
- Organizer
  第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] ホメオスタシスの観点から考えるてんかん治療の標的分子. (シンポジウム).2018
- Author(s)
  永井拓, Shan Wei, 山田清文.
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] Role of striatal phosphorylation signaling in emotional behaviors. (ワークショップ).2018
- Author(s)
  永井拓, 貝淵弘三.
- Organizer
  第41回日本分子生物学会年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] 統合失調症の克服を目指したリバーストランスレーショナルリサーチ. (シンポジウム).2018
- Author(s)
  永井拓, 尾崎紀夫, 山田清文.
- Organizer
  第28回日本医療薬学会年会.
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] 免疫活性化によって誘導されるアストロサイト由来MHC class Iの病態生理学的役割. (シンポジウム).2018
- Author(s)
  永井拓.
- Organizer
  第61回日本神経化学会大会・第40回日本生物学的精神医学会.
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] 免疫活性化によって誘導されるアストロサイト由来MHC class Iの病態生理学的役割. (シンポジウム).2018
- Author(s)
  永井拓.
- Organizer
  第61回日本神経化学会大会・第40回日本生物学的精神医学会.
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] 自然免疫系の過剰な活性化はアストロサイト由来主要組織適合抗原I型を介して異常行動を引き起こす. (シンポジウム).2018
- Author(s)
  永井拓, 祖父江顕, 山田清文.
- Organizer
  第34回日本ストレス学会学術総会.
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] 脳機能を制御するリン酸化シグナルの解明に関する研究.2017
- Author(s)
  永井拓.
- Organizer
  第60回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Phosphorylation signals in reward-motivated behaviors.2017
- Author(s)
  永井拓, 貝淵弘三.
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] ドパミン神経伝達により引き起こされる神経興奮と報酬関連行動の細胞内シグナル.2017
- Author(s)
  永井拓, 黒田啓介, 貝淵弘三.
- Organizer
  第40回日本神経科学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] 11.IFITM3 regulates polyI:C-induced neuronal impairment through RabGDI.2017
- Author(s)
  Norimichi Itoh, Taku Nagai, Daisuke Ibi, Akira Nakajima, Toshitaka Nabeshima, Kiyofumi Yamada.
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16K15201
[Presentation] ペンチレンテトラゾール誘発てんかん発作におけるNpas4の役割.2017
- Author(s)
  永井拓, Shan Wei, 田中基樹, 鍋島俊隆, 曽我部正博, 山田清文.
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] ペンチレンテトラゾール誘発てんかん発作におけるNpas4の役割.2017
- Author(s)
  永井拓, Shan Wei, 田中基樹, 鍋島俊隆, 曽我部正博, 山田清文.
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会.
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Npas4 mediates pentylenetetrazole-induced Homer1a expression in the hippocampus.2017
- Author(s)
  2.永井拓, Shan Wei, 田中基樹, 鍋島俊隆, 曽我部正博, 山田清文.
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] 脳機能を制御するリン酸化シグナルの解明に関する研究.2017
- Author(s)
  永井拓
- Organizer
  第60回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] Phosphorylation signals in reward-motivated behaviors.2017
- Author(s)
  永井拓, 貝淵弘三.
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19483
[Presentation] ドパミン神経伝達により引き起こされる神経興奮と報酬関連行動の細胞内シグナル.2017
- Author(s)
  永井拓, 黒田啓介, 貝淵弘三.
- Organizer
  第40回日本神経科学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Npas4 mediates pentylenetetrazole-induced Homer1a expression in the hippocampus.2017
- Author(s)
  永井拓, Shan Wei, 田中基樹, 鍋島俊隆, 曽我部正博, 山田清文
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17H02220
[Presentation] Flexシステムを用いた脳内報酬系の解析：ドパミンD1受容体発現中型有棘細胞の動作メカニズムの解明.2016
- Author(s)
  永井拓, 天野睦紀, 山田清文, 貝淵弘三.
- Organizer
  第89回日本薬理学会年会.
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] 薬物依存症の克服を目指した分子基盤研究2015
- Author(s)
  永井拓
- Organizer
  平成27年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  兵庫県神戸市神戸国際会議場
- Year and Date
  2015-10-11
- Invited
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] 報酬シグナルの同定と報酬回路の制御機構2015
- Author(s)
  永井拓
- Organizer
  平成27年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  兵庫県神戸市神戸国際会議場
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] 報酬関連行動を制御するシグナル伝達2015
- Author(s)
  永井拓
- Organizer
  蛋白研セミナー・包括脳ネットワーク研究会「第6回神経科学と構造生物学の融合研究会」
- Place of Presentation
  愛知県岡崎市生理学研究所
- Year and Date
  2015-11-26
- Invited
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] リン酸化Girdinによる神経可塑性の制御2015
- Author(s)
  永井拓, 中井剛, 田中基樹, 浅井直也, 榎本篤, 曽我部正博, 高橋雅英, 山田清文.
- Organizer
  第24回神経行動薬理若手研究者の集い
- Place of Presentation
  愛知県名古屋市、名城大学名駅サテライトキャンパス
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] ドパミン神経伝達を介した報酬シグナルの多面的解析2015
- Author(s)
  269.永井拓
- Organizer
  平成27年度生理学研究所研究会「情動の多次元的理解に基づく行動原理の探求」
- Place of Presentation
  愛知県岡崎市生理学研究所
- Year and Date
  2015-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] リン酸化プロテオミクスによる報酬シグナルの解明2015
- Author(s)
  永井拓, 天野睦紀, 山田清文, 貝淵弘三
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  埼玉県さいたま市大宮ソニックシティ
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] PolyI:C誘発性神経発達障害モデルの有用性 (シンポジウム: 統合失調症失調症の生物学的研究の進歩－遺伝子特性～創薬の種の最前線－)2013
- Author(s)
  永井拓
- Organizer
  第8回日本統合失調症学会
- Place of Presentation
  北海道浦河郡、浦河町総合文化会館, 浦河ウエリントンホテル
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via glucocorticoid receptor in the brain2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  11th WFSBP
- Place of Presentation
  京都市　京都国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via glucocorticoid receptor in the brain2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  11th WFSBP
- Place of Presentation
  京都府京都市京都国際会館
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 脳特異的転写因子Npas4欠損マウスにおける異常行動とGABA作動性神経系マーカーの変化2013
- Author(s)
  日比(古川)陽子, 横井順平, 永井拓, 山田清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Year and Date
  2013-07-12
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイド受容体は神経分化関連因子NPAS4の転写を直接抑制するDirect transcriptional regulation of neuronal transcription factor Npas4 by glucocorticoid receptor2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡県博多市福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイド受容体は神経分化関連因子NPAS4の転写を直接抑制する Direct transcriptional regulation of neuronal transcription factor Npas4 by glucocorticoid receptor2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 長期ストレスはGABA神経関連転写因子Npas4遺伝子のDNAメチル化を亢進する Chronic stress increases DNA methylation of Neuronal PAS domain 4 (Npas4)2013
- Author(s)
  日比（古川）　陽子、永井　拓、山田　清文
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  宜野湾市　沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 長期ストレスはGABA神経関連転写因子Npas4遺伝子のDNAメチル化を亢進するChronic stress increases DNA methylation of Neuronal PAS domain 4 (Npas4)2013
- Author(s)
  日比(古川)陽子, 永井拓, 山田清文
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄県宜野湾市沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ドパミン作動性およびグルタミン酸作動性神経伝達の変調と障害に関する神経精神薬理学的研究 (日本神経精神薬理学会 2012 年第1回学術奨励賞受賞講演)2012
- Author(s)
  永井拓
- Organizer
  第22回日本臨床精神神経薬理学会・第42回日本神経精神薬理学会合同年会
- Place of Presentation
  宇都宮,栃木県総合文化センター/宇都宮東武ホテルグランデ
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] Glucocorticoid reduces the gene expression of neuronal PAS domain 4 (Npas4) in the brain2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  ASCB2012
- Place of Presentation
  サンフランシスコ　USA
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ドパミン作動性およびグルタミン酸作動性神経伝達の変調と障害に関する神経精神薬理学的研究2012
- Author(s)
  永井拓
- Organizer
  第22回日本臨床精神神経薬理学会・第42回日本神経精神薬理学会合同年会
- Place of Presentation
  栃木県総合文化センター
- Invited
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] Glucocorticoid reduces the gene expression of neuronal PAS domain 4 (Npas4) in the brain2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  ASCB2012
- Place of Presentation
  USAサンフランシスコ
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  The 11th APSN,The 55th J SN(日本神経化学会)
- Place of Presentation
  兵庫県神戸市神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 周産期免疫異常応答によって惹起される精神発達障害とそのメカニズム2012
- Author(s)
  永井拓, 衣斐大祐, 山田真之亮, 山田清文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] Stress regulates the gene expression of neuronal PAS domain 4 (Npas4), via glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  CINP 2012
- Place of Presentation
  スウェーデンストックホルム
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイドによる転写因子NPAS4の発現抑制機構Glucocorticoid regulates the expression of neuronal PAS domain 4 (Npas4)2012
- Author(s)
  日比陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第7回統合失調症学会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress regulates the gene expression of neuronal PAS domain 4 (Npas4), via glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  CINP 2012
- Place of Presentation
  ストックホルム　スウェーデン
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress regulates the gene expression of neuronal transcription factor Npas4 via glucocorticoid2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  第４回GCOE国際シンポジウム
- Place of Presentation
  名古屋キャッスルホテル（愛知）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ブチリルコリンエステラーゼ阻害剤のアミロイドベータ誘発性認知機能障害改善効果Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice2012
- Author(s)
  日比(古川)陽子, アルカム・トルソン, 新田淳美, 松山明裕, 永井拓, 山田清文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府京都市京都国際会館
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation]2012
- Author(s)
  Yamada K, Ibi D, Nakajima A, Yamada S, Mizoguchi H, Nabeshima T and Nagai T
- Organizer
  8thFENS Forum of Neuroscience
- Place of Presentation
  Barcelona International Convention Center
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] 統合失調症モデル動物を用いたプロテオーム解析2012
- Author(s)
  永井拓, 山田清文, 鍋島俊隆
- Organizer
  第7回日本統合失調症学会
- Place of Presentation
  ウインクあいち（愛知県）
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] Stress regulates the gene expression of neuronal transcription factor Npas4 via glucocorticoid2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  第4回GCOE国際シンポジウム
- Place of Presentation
  愛知県名古屋市ウエスティンナゴヤキャッスルホテル
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 精神疾患モデル動物を用いた神経精神薬理学的研究2012
- Author(s)
  永井拓
- Organizer
  第16回日本神経麻酔・集中治療研究会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Invited
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  The 11th APSN The 55th JSN（日本神経化学会）
- Place of Presentation
  神戸国際会議場（兵庫）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 新生仔期polyI:C処置による神経発達障害にはアストロサイトのIFITM3が関与している2012
- Author(s)
  永井拓, 鍋島俊隆, 山田清文
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] 精神疾患モデル動物を用いた神経精神薬理学的研究 (特別講演)2012
- Author(s)
  永井拓
- Organizer
  第16回日本神経麻酔・集中治療研究会
- Place of Presentation
  岡山,岡山コンベンションセンター/岡山大学
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] 周産期における異常免疫応答と神経発達障害2011
- Author(s)
  永井拓
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京,京王プラザホテル
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] プロテアーゼを介した薬物依存形成の神経化学的機序2011
- Author(s)
  永井拓.
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] 遺伝子―環境相互作用に基づいた統合失調症モデル動物における抗精神病薬の効果.2011
- Author(s)
  永井拓, 北原裕子, 衣斐大祐, 鍋島俊隆, 澤明, 山田清文.
- Organizer
  第57回日本薬学会東海支部総会・大会
- Place of Presentation
  金城学院大学（愛知県）
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] 神経精神発達に対する幼若期ストレスの影響2011
- Author(s)
  永井拓, 尹錫在, 日比陽子, 山田清文
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀, 瑠璃光
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] 神経発達関連転写因子NPAS4のストレスによる転写抑制機構の解明2011
- Author(s)
  日比(古川)陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 周産期免疫応答異常によって誘発される精神機能発達障害に対するニコチンの効果2011
- Author(s)
  永井拓
- Organizer
  第21回日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Place of Presentation
  ウィンクあいち(愛知県)
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] 神経精神発達に対する幼若期ストレスの影響2011
- Author(s)
  永井拓, 尹錫在, 日比陽子, 山田清文
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光（石川県）
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] プロテアーゼを介した薬物依存形成の神経化学的機序2011
- Author(s)
  永井拓
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京,京王プラザホテル
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] Stress reduces the expression of transcription factor, neuronal PAS domain 4 (NPAS4)2011
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  AsCNP2011
- Place of Presentation
  韓国ソウル市
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ストレスによるneuronal PAS domain 4 (NPAS4)の転写制御Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by stress2011
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 神経発達関連転写因子NPAS4の発現調節機構の解明2011
- Author(s)
  日比(古川)陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 周産期における異常免疫応答と神経発達障害2011
- Author(s)
  永井拓
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation] 遺伝子-環境相互作用に基づいた統合失調症モデル動物における抗精神病薬の効果2011
- Author(s)
  永井拓
- Organizer
  第57回日本薬学会東海支部総会・大会
- Place of Presentation
  金城学院大学(愛知県)
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Npas4 regulates neurite outgrowth and phosphorylation of synapsinI2011
- Author(s)
  尹錫在, 永井拓, 日比陽子, 黒田啓介, 貝淵弘三, 山田清文
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京,京王プラザホテル
- Data Source
  KAKENHI-PROJECT-23790081
[Presentation]2010
- Author(s)
  衣斐大祐、永井拓、中島晶、鍋島俊隆、山田清文
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台仙台国際センター
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] 周産期の免疫異常が神経精神発達におよぼす影響(シンポジウム)2010
- Author(s)
  永井拓
- Organizer
  Neuro2010第33回日本神経科学大会、第53回日本神経化学会大会、第20回日本神経回路学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] 新生仔期polyI:C処置によって誘発される不安様行動および学習記憶障害2010
- Author(s)
  永井拓, 于静華, 北原裕子, 衣斐大祐, 鍋島俊隆, 山田清文
- Organizer
  第20回日本医療薬学会年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] 新生仔期polyI : C処置によって誘発される不安様行動および学習記憶障害2010
- Author(s)
  永井拓, 他
- Organizer
  第20回日本医療薬学会年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Polyl : C誘発性神経発達障害におけるInterferon-induced transmembrane protein 3の役割2010
- Author(s)
  永井拓, ら
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] 周産期の免疫異常が神経精神発達におよぼす影響(シンポジウム).2010
- Author(s)
  永井拓, 衣斐大祐, 鍋島俊隆, 澤明, 山田清文
- Organizer
  Neuro2010第33回日本神経科学大会、第53回日本神経化学会大会、第20回日本神経回路学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] 新生仔期polyI : C処置によって誘発される不安様行動および学習記憶障害2010
- Author(s)
  永井拓
- Organizer
  第20回日本医療薬学会年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] 新生仔期polyI : C処置によって誘発される不安様行動および学習記憶障害2010
- Author(s)
  永井拓, ら
- Organizer
  第20回日本医療薬学会年会
- Place of Presentation
  千葉
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] Methamphetamine increased Npas4, a neuronal PAS domain 4 expression; a possible role in neurite outgrowth and phosphorylated synapsin I expression.2010
- Author(s)
  永井拓, 山田清文
- Organizer
  第45回日本アルコール・薬物医学会、第22回日本アルコール精神医学会、第13回ニコチン・薬物依存研究フォーラム、2010アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  小倉
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] Methamphetamine increased Npas4, a neuronal PAS domain 4 expression ; a possible roic in neurite outgrowth and phosphorylated synapsin I expression.2010
- Author(s)
  永井拓
- Organizer
  第45回日本アルコール・薬物医学会、第22回日本アルコール精神医学会、第13回ニコチン・薬物依存研究フォーラム、平成22年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  小倉
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] 周産期の免疫異常が神経精神発達におよぼす影響2010
- Author(s)
  永井拓, ら
- Organizer
  第33回日本神経科学大会・第53回日本神経科学会大会・第20回日本神経回路学会Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] Neonatal poly : C treatment in mice induces schizophrenia-like behavioral and neurochemial abnomalities in adulthood2009
- Author(s)
  Nagai T, et al.
- Organizer
  Society for Neuroscience2009
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 統合失調症モデル動物を用いたプロテォーム解析2009
- Author(s)
  永井拓, 鍋島俊隆
- Organizer
  名城大学学術フロンティア事業第1回若手シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-03-02
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] Neonatal polyI : C treatment in mice induces schizophrenia-like behavioral and neurochemical abnormalities in adulthood.2009
- Author(s)
  Nagai T
- Organizer
  Neuroscience 2009, the 39th annual meeting of the Society for Neuroscience.
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] Neonatal polyI : C treatment in mice induces schizophrenia-like behavioral and neurochemical abnormalities in adulthood.2009
- Author(s)
  永井拓, et al
- Organizer
  The 39th annual meeting of the Society for Neuroscience (2009)
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] ニコチンの報酬効果における組織プラスミノーゲン活性化因子の関与2009
- Author(s)
  永井拓, 鍋島俊隆, 山田清文
- Organizer
  第44回日本アルコール・薬物医学会総会・第21回日本アルコール精神医学会・第12回ニコチン・薬物依存研究フォーラム平成21年度合同学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] 統合失調症モデル動物を用いたプロテオーム解析2009
- Author(s)
  永井拓、鍋島俊隆
- Organizer
  名城大学学術フロンティア事業第1回若手シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-03-02
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] Roles of a novel molecule 'shati' in the development of methamphetamine-induced dependence2009
- Author(s)
  Toshitaka Nabeshima, Minae Niwa, Xiaobo Cen, Hiroyuki Mizoguchi, Yasutomo Itoh, Kiyoyuki Kitaichi, Taku Nagai, Norio Ozaki, Yukihiro Noda, Atsumi Nitta
- Organizer
  The Second Annual International Drug Abuse Research Society/International Society for Neurochemistry Satellite Meeting
- Place of Presentation
  韓国
- Year and Date
  2009-08-18
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] Neonatal polyI:C treatment in mice induces schizophrenia-like behavioral and neurochemical abnormalities in adulthood.2009
- Author(s)
  Nagai, T., Ibi, D., Mizoguchi, H., Nabeshima, T., Yamada, K.
- Organizer
  Neuroscience 2009, the 39th annual meeting of the Society for Neuroscience.
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] ニコチンの報酬効果における組織プラスミノーゲン活性化因子の関与(シンポジウム)2009
- Author(s)
  永井拓, 鍋島俊隆, 山田清文
- Organizer
  第44回日本アルコール・薬物医学会、第21回日本アルコール精神医学会、第12回ニコチン・薬物依存研究フォーラム2009合同学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] ニコチンの報酬効果における組織プラスミノーゲン活性化因子の関与(シンポジウム)2009
- Author(s)
  永井拓
- Organizer
  第44回日本アルコール・薬物医学会、第21回日本アルコール精神医学会、第12回ニコチン・薬物依存研究フォーラム平成21年度合同学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790067
[Presentation] Synergistic impacts of DISC1 mutation and neonatal polyI : C treatment on adult phenotypes in mice : A novel mouse model of schizophrenia with gene-environment interactions2009
- Author(s)
  Nagai T, et al.
- Organizer
  9th World Congress of Biological Psychiatry
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 周産期における免疫異常は春期マウスにおける情動および認知機能を障害する2008
- Author(s)
  永井拓, 衣斐大祐, 溝口博之, 鍋島俊隆, 山田清文
- Organizer
  第2回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] モルヒネ誘発性精神障害におけるtP A-ブラスミンシステムの役割. (日本生物学的精神医学会合同シンポジウム「神経化学と精神医学の融合による精神疾患病態解明・治療法開発」)2008
- Author(s)
  永井拓, 他
- Organizer
  第51回日本神経化学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] モルヒネ誘発性精神障害におけるtPA-プラスミンシステムの役割2008
- Author(s)
  永井拓
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] フェンシクリジン誘発認知記憶障害に対するアリピプラゾールの効果.2008
- Author(s)
  永井拓, 村井里菜, 松井香奈枝, 亀井浩行, 野田幸裕, 古川宏, 鍋島俊隆
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] モルヒネ誘発性精神障害におけるtPA-プラスミンシステムの役割2008
- Author(s)
  永井拓, 鍋島俊隆, 山田清文
- Organizer
  日本生物学的精(医学会合同シンポジウム). 第51回日本神経化学会大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] Role of tP A-plasmin System in Neuropsychological Abnormalities induced by Morphine. (Joint Symposium with JSN "Clues to the Pathophysiology and Treatment of Psychiatric Disorders through Integrating Neurochemistry and Psychiatry")2008
- Author(s)
  Nagai T, et al.
- Organizer
  2nd WFSBP Asia-Pacific Congress and 30th Annual Meeting of JSBP
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 周産期polyinosine:polycytidylic acid投与による神機能発達およびグルタミン酸作動性神経系の変化2008
- Author(s)
  永井拓, 北原裕子, 衣斐大祐, 山田清文
- Organizer
  第119回マイクロダイアリシス研究会
- Place of Presentation
  東京
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] Activation of postsynaptic dopamine D1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling.2008
- Author(s)
  Nagai T, et al.
- Organizer
  International Symposium on Brain Development and Neuropsychiatric Disorders
- Place of Presentation
  名古屋
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 周産期における免疫異常は思春期マウスにおける情動および認知機能を障害する2008
- Author(s)
  永井拓, ら
- Organizer
  第2回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20390073
[Presentation] 周産期における免疫異常は思春期マウスにおける情動および認知機能を障害する2008
- Author(s)
  永井拓
- Organizer
  第2回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] 周産期polyinosine : polycytidylic acid投与による精神機能発達およびグルタミン酸作動性神経系の変化2008
- Author(s)
  永井拓
- Organizer
  第119回マイクロダイアリシス研究会
- Place of Presentation
  東京
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] 周産期における免疫異常は思春期マウスにおける情動および認知機能を障害する.2008
- Author(s)
  永井拓, 他
- Organizer
  第2回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Tissue plasminogen activator-plasmin-protease activated receptor l system regulatesrewarding effect of nicotine.2007
- Author(s)
  Nagai T, et. al.
- Organizer
  69th Annual Meeting of College on Problems of Drug Dependence
- Place of Presentation
  Quebec City, Canada
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 組織プラスミノーゲン活性化因による依存性薬物の報酬効果の制御 (シンポジウム)2007
- Author(s)
  永井拓, 田熊一敞, 溝口博之, 鍋島俊隆, 山田清文
- Organizer
  第29回日本生物的精神医学会・第37回日本神経精神薬理学会合同年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19790053
[Presentation] 覚せい剤による依存・精神病性障害と認知機能障害における組織プラスミノーゲン活性化因子の関与(シンポジウム「アルコール・薬物依存の基礎研究の動向」).2007
- Author(s)
  山田清文, 永井拓, 溝口博之, 鍋島俊隆, 田熊一敞
- Organizer
  第42回日本アルコール・薬物医学会, 第19回日本アルコール精神医学会, 第10回ニコチン・薬物依存研究フォーラム平成19年度合同学術総会.
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 組織プラスミノーゲン活性化因子による依存性薬物の報酬効果の制御.(シンポジウム)「薬物依存-臨床応用への可能性」)2007
- Author(s)
  永井拓, 他
- Organizer
  第29回日本生物学的精神医学会・第37回日本神経精神薬理学会合同年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 精神発達に及ぼす遺伝―環境因子の影響に関する研究
- Author(s)
  永井拓
- Organizer
  第59回日本薬学会東海支部総会・大会
- Place of Presentation
  愛知県名古屋市、名城大学
- Invited
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] 神経発達関連転写因子NPAS4の発現調節機構の解明
- Author(s)
  日比（古川）陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 脳特異的転写因子Npas4欠損マウスにおける異常行動とGABA作動性神経系マーカーの変化
- Author(s)
  日比（古川）　陽子、横井　順平、永井　拓、山田　清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  名古屋市　ウインク愛知
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] リン酸化GirdinはNMDA受容体を介して神経可塑性を制御する
- Author(s)
  永井拓, 中井剛, 田中基樹, 浅井直也, 榎本篤, 曽我部正博, 高橋雅英, 山田清文.
- Organizer
  第24回日本臨床精神神経薬理学会・第44回日本神経精神薬理学会合同年会
- Place of Presentation
  愛知県名古屋市、名古屋国際会議場
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] グルココルチコイドによる転写因子NPAS4の発現抑制機構 Glucocorticoid regulates the expression of neuronal PAS domain 4 (Npas4).
- Author(s)
  日比　陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第7回統合失調症学会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Npas4 regulates neurite outgrowth and phosphoryation of synapsin I
- Author(s)
  Jaesuk Yun, Taku Nagai, Yoko Hibi, Keisuke Kuroda, Kozo Kaibuchi, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Methamphetamine-induced Npas4; possible role in neurite outgrowth and p-synapsin I expression
- Author(s)
  Yun Jaesuk, Nagai Taku, Hibi Yoko, Kuroda Keisuke, Kaibuchi Kozo,Yamada Kiyofumi
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 脳内報酬系の分子基盤
- Author(s)
  永井拓
- Organizer
  第49回日本アルコール・薬物医学会、第36回日本アルコール関連問題学会、第26回日本依存神経精神科学会合同学術総会.
- Place of Presentation
  神奈川県横浜市、パシフィコ横浜
- Year and Date
  2014-10-03 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] Matrix metalloproteinase-3とpolyI:C誘発性自然免疫活性化により惹起される神経発達障害.
- Author(s)
  永井拓, 山田真之亮, 山田清文.
- Organizer
  第37回日本神経科学大会 (Neuroscience2014)
- Place of Presentation
  神奈川県横浜市、パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] Matrix metalloproteinase-3 mediates neurodevelopmental impairment due to polyI:C-induced innate immune activation.
- Author(s)
  永井拓, 山田真之亮, 山田清文.
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本県、熊本市、熊本大学薬学部多目的ホール
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] Intracellular signal transduction in the brain reward system
- Author(s)
  永井拓
- Organizer
  第88回日本薬理学会年会 (シンポジウム)
- Place of Presentation
  愛知県名古屋市、名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460093
[Presentation] 神経発達関連転写因子NPAS4のストレスによる転写抑制機構の解明
- Author(s)
  日比（古川）陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by stress ストレスによるneuronal PAS domain 4 (NPAS4)の転写制御
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] The Role of Npas4 in Neurite Outgrowth and phosphorylation of Synapsin I
- Author(s)
  Jaesuk Yun, Taku Nagai, Yoko Hibi, Keisuke Kuroda, Kozo Kaibuchi, Kiyofumi Yamada
- Organizer
  AsCNP
- Place of Presentation
  韓国　ソウル
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress reduces the expression of transcription factor, neuronal PAS domain 4 (NPAS4)
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai and Kiyofumi Yamada
- Organizer
  AsCNP
- Place of Presentation
  韓国　ソウル
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 新生仔期polyI:C処置マウスの異常行動に対する抗精神病薬の効果とプロテオーム解析
- Author(s)
  永井拓,千崎康司, Yu Jinghua, 山田清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市、ウインクあいち
- Data Source
  KAKENHI-PROJECT-25460093
[]

1. YAMADA Kiyofumi (30303639)

# of Collaborated Projects: 8 results

# of Collaborated Products: 71 results
2. MIZOGUCHI Hiroyuki (70402568)

# of Collaborated Projects: 6 results

# of Collaborated Products: 22 results
3. TAKUMA Kazuhiro (90289025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. 伊藤教道 (30726310)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. HIBI Yoko (70295616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 41 results
6. NABESHIMA Toshitaka (70076751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
7. MAMIYA Takayoshi (70340297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. NIWA Minae (60469046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. MOURI Akihiro (20597851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. ASAI Naoya (80273233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. Kaibuchi Kozo (00169377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
12. 尾崎紀夫 (40281480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 天野睦紀 (90304170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. 西岡朋生 (70435105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 黒田啓介 (80631431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
16. 船橋靖広 (00749913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 窪田悠力 (00853227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 張心健 (10850430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 松崎哲郎 (80866450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. Zhu Youyun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MURAKAMI Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. TORIUMI Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. TAKAO Kohno

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. WATANABE Hirohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. UCHIGASHIMA Motokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. ENOMOTO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. DAISUKE Mori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. TSUBOI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. TANAKA Tetsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. ETO Kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. NODA Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 山中章弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 山橋幸恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 石垣診祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 祖父江元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 高橋雅英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 小西博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 田中啓治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 山森哲雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 田中真樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 田中謙二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 阿部修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 森寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 祖父江顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 仲嶋一範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 衣斐大祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGAI TAKU 永井 拓

NAGAI Taku 永井 拓

Research Projects

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パーキンソン病における意思決定障害の分子・神経メカニズム解明と新規治療薬開発Principal Investigator

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Study on development of novel antipsychotics based on reverse translational researchPrincipal Investigator

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Development an in vivo real-time analytical system that can predict dependency and rewarding effects of novel compoundsPrincipal Investigator

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Study on the neural mechanism controlling emotional behaviorsPrincipal Investigator

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Study on the neurodevelopmental abnormalities induced by the innate immune activation during perinatal periodPrincipal Investigator

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ROLE OF TRANSCRIPTION FACTOR NPAS4 IN DRUG DEPENDENCEPrincipal Investigator

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NAGAI TAKU 永井拓

NAGAI Taku 永井拓

[Book] 実践行動薬理学(第□編応用編:行動薬理研究の現在、第4章報酬機構関連、3.依存性薬物による精神障害の分子機序)2010