AOKI Rui 青木類

Researcher Number	10377541
Affiliation (based on the past Project Information) *help	2015: 山梨大学, 総合研究部, 助教 2009 – 2014: University of Yamanashi, 医学部附属病院, 助教 2006: University of Yamanashi, University of Yamanashi Hospital, Instructor, 大学院医学部附属病, 医員 2005 – 2006: 山梨大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator マスト細胞 / HSV / 自然免疫 / 単純ヘルペスウイルス / IL-33 / ウイルス / innate immunity / mast cell / 皮膚感染症 Except Principal Investigator Toll-like receptor … More / Herpes simplex virus / 自然免疫 / Acquired immunity / Innate immunity / Mast cell / 獲得免疫 / マスト細胞 / 経皮感染 / ＨＩＶ / ＨＳＶ / 性行為HIV感染 / HIV感染 / ランゲルハンス細胞 / 抗菌ペプチド / HSV-2 / HIV / コネキシン / ギャップ結合 / 樹状細胞 / 抗炎症剤 / 免疫抑制剤 / シグナル伝達 / 薬理学 / 免疫学 Less

HSV感染防御におけるマスト細胞の役割の解明Principal Investigator
- Principal Investigator
  
  青木類
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
The role of mast cells on host defense against lethal herpes simplex virus infectionPrincipal Investigator
- Principal Investigator
  
  AOKI Rui
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Examination of the participation in HIV infection of the VitaminD3 and HSV-2 using the humanized mouse
- Principal Investigator
  
  SHIMADA Shinji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
The role of mast cells on host defense against lethal herpes simplex virus infectionPrincipal Investigator
- Principal Investigator
  
  AOKI Rui
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
ギャップ結合の免疫における役割の解明とその遮断による抗炎症剤/免疫抑制剤の開発
- Principal Investigator
  
  MATSUE Hiroyuki
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Roles of mast cells on viral infection and mast cell-based immunotherapy
- Principal Investigator
  
  SHIMADA Shinji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi

All 2015 2013 2012 2010 2009 2006 Other

All Journal Article Presentation

[Journal Article] IL-33とウイルス感染皮膚ヘルペス感染におけるAlarminとしてのIL-33の重要性2015
- Author(s)
  青木類, 川村龍吉
- Journal Title
  
  医学のあゆみ
  
  Volume: 252(12) Pages: 1221-1225
- Data Source
  KAKENHI-PROJECT-26461684
[Journal Article] IL-33とウイルス感染　皮膚ヘルペス感染におけるalarminとしてのIL-33の重要性2015
- Author(s)
  青木類、川村龍吉
- Journal Title
  
  医学のあゆみ
  
  Volume: 252巻12号 Pages: 1221-1225
- Data Source
  KAKENHI-PROJECT-26461684
[Journal Article] Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.2015
- Author(s)
  Ando N, Nakamura Y, Aoki R, Ishimaru K, Ogawa H, Okumura K, Shibata S, Shimada S, Nakao A
- Journal Title
  
  J Invest Dermatol
  
  Volume: 135 Issue: 12 Pages: 3001-3008
- DOI
  10.1038/jid.2015.316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-26220201, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-26461684, KAKENHI-PROJECT-26670475, KAKENHI-PROJECT-26860874, KAKENHI-PROJECT-26293087
[Journal Article] Antimicrobial peptide LL-37 produced by HSV-2-infected keratinocytes enhances HIV infection of Langerhans cells2013
- Author(s)
  Ogawa Y, Kawamura T, Matsuzawa T, Aoki R, Gee P, Yamashita A, Moriishi K, Yamasaki K, Koyanagi Y. Blauvelt A, Shimada S.
- Journal Title
  
  Cell Host and Microbe
  
  Volume: 13 Issue: 1 Pages: 77-86
- DOI
  10.1016/j.chom.2012.12.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05331, KAKENHI-PROJECT-22590724, KAKENHI-PROJECT-23390282, KAKENHI-PROJECT-23591637, KAKENHI-PROJECT-23591641, KAKENHI-PROJECT-24390112, KAKENHI-PROJECT-24591622, KAKENHI-PROJECT-24791144
[Journal Article] Antimicrobial Peptide LL-37 Produced by HSV-2-Infected Keratinocytes Enhances HIV Infection of Langerhans Cells2013
- Author(s)
  Youichi Ogawa, Tatsuyoshi Kawamura, Takamitsu Matsuzawa, Rui Aoki, Peter Gee, Atsuya Yamashita, Kohji Moriishi, Kenshi Yamasaki, Yoshio Koyanagi, Andrew Blauvelt, and Shinji Shimada
- Journal Title
  
  Cell Host and Microbe
  
  Volume: 13 Pages: 77-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659545
[Journal Article] Oral administration of the CCR5 inhibitor , maraviroc, blocks HIV ex vivo infection of Langerhans cells within the epithelium2013
- Author(s)
  Matsuzawa T, Kawamura T, Ogawa Y, Takahashi M, Aoki R, Moriishi K, Koyanagi Y, Gatanaga H, Blauvelt A, Shimada S
- Journal Title
  
  J Invest Dermatol
  
  Volume: 133(12) Issue: 12 Pages: 2803-5
- DOI
  10.1038/jid.2013.215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282, KAKENHI-PROJECT-23591641, KAKENHI-PLANNED-24115008, KAKENHI-PROJECT-24390112, KAKENHI-PROJECT-24791143, KAKENHI-PROJECT-24791144
[Journal Article] Mast cells play a key role in host defense against herpes simplex virus infection through TNF-α and IL-6 production2013
- Author(s)
  Aoki R, Kawamura T, Goshima F, Ogawa Y, Nakae S, Nakao A, Moriishi K, Nishiyama Y, Shimada S
- Journal Title
  
  J Invest Dermatol
  
  Volume: 133(9) Issue: 9 Pages: 2170-9
- DOI
  10.1038/jid.2013.150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282, KAKENHI-PROJECT-23591641, KAKENHI-PROJECT-23659499, KAKENHI-PROJECT-24791144
[Journal Article] Mast Cells Play a Key Role in Host Defense against Herpes Simplex Virus Infection through TNF-α and IL-6 Production.2013
- Author(s)
  Aoki R, Kawamura T, Goshima F, Ogawa Y, Nakae S, Nakao A, Moriishi K, Nishiyama Y, Shimada S.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 133(9) Pages: 2170-2179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791144
[Journal Article] Mast cells play a key role in host defense against herpes simplex virus infection through TNF-α and IL-6 production2013
- Author(s)
  Rui Aoki
- Journal Title
  
  Journal of investigative dermatology
  
  Volume: 133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791144
[Journal Article] A case of Lymphoepithelioma-like Carcinoma of the Skin associated with Epstein-Barr virus infection2010
- Author(s)
  Rui Aoki, Hiroshi Mitsui, Kazutoshi Harada, Tatsuyoshi Kawamura, Naotaka Shibagaki, Katsuhiko Tsukamoto, Shin-ichi Murata, Shinji Shimada
- Journal Title
  
  Journal of the American Academy of Dermatology. 62(4)
  
  Pages: 681-684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791068
[Journal Article] Gap junction-mediated intercellular communication between dendritic cells (DCs) is required for effective activation of DCs.2006
- Author(s)
  Matsue, H., Yao, J., Matsue, K., Nagasaka, A., Sugiyama, H., Aoki, R., Kitamura, M., Shimada, S.
- Journal Title
  
  J. Immunol. 176
  
  Pages: 181-190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390310
[Presentation] 皮膚ヘルペス感染におけるAlarminとしてのIL-33の重要性2015
- Author(s)
  青木類、川村龍吉、五島典、小川陽一、中江進、中尾篤人、島田眞路
- Organizer
  第３回ケラチノサイトと免疫を勉強する会
- Place of Presentation
  帝国ホテル(東京)
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26461684
[Presentation] The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cell-mediated antiviral innate immunity2013
- Author(s)
  青木類
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh (Scotland)
- Year and Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-24791144
[Presentation] The alarmin IL- 33 derived from HSV- 2- infected keratinocytes triggers mast cell- mediated antiviral innate immunity2013
- Author(s)
  Rui Aoki
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh International Conference Centre (Edinburgh, Scotland)
- Data Source
  KAKENHI-PROJECT-24791144
[Presentation] Antimicrobial Peptide LL-37 Produced by HSV-2-Infected Keratinocytes Enhances HIV Infection of Langerhans Cells2013
- Author(s)
  Youichi Ogawa, Tatsuyoshi Kawamura, Takamitsu Matsuzawa, Rui Aoki, Andrew Blauvelt, and Shinji Shimada
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Year and Date
  2013-05-09
- Data Source
  KAKENHI-PROJECT-23659545
[Presentation] The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cell-mediated antiviral innate immunity2013
- Author(s)
  Rui Aoki
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh International Conference Centre (Edinburgh, Scotland)
- Data Source
  KAKENHI-PROJECT-24791144
[Presentation] IL-33 triggers mast cell-mediated innate immunity against lethal herpes simplex virus infection through TNF-α and IL-62012
- Author(s)
  Rui Aoki
- Organizer
  European Society for Dermatological Research
- Place of Presentation
  Plazzo del Casino, Venice Lido Congress Centre (Venice, Italy)
- Data Source
  KAKENHI-PROJECT-24791144
[Presentation] IL-33 triggers mast cell-mediated innate immunity against lethal herpes simplex virus infection through TNF-α and IL-62012
- Author(s)
  青木類
- Organizer
  The 37th Annual Meeting of Japanese Society for Investigative Dermatology
- Place of Presentation
  沖縄
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-24791144
[Presentation] IL-33 triggers mast cell-mediated innate immunity against lethal herpes simplex virus infection through TNF-α and IL-62012
- Author(s)
  Rui Aoki
- Organizer
  Japanese Society for Investigative Dermatology
- Place of Presentation
  Loisir Hotel & Spa Tower (那覇、沖縄)
- Data Source
  KAKENHI-PROJECT-24791144
[Presentation] IL-33 triggers mast cell-mediated innate immunity against lethal herpes simplex virus infection through TNF-α and IL-62012
- Author(s)
  青木類
- Organizer
  The 42th Annual European Society for Dermatological Research meeting
- Place of Presentation
  Venice(Italy)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24791144
[Presentation] Mast cells play a key role in host defense against lethal herpes simplex virus infection2010
- Author(s)
  青木類
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells play a key role in host defense against lethal herpes simplex virus infection2010
- Author(s)
  青木類
- Organizer
  European Society for Dermatological Research
- Place of Presentation
  ヘルシンキ(フィンランド)
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells play a key role in host defense against lethal herpes simplex virus infection2010
- Author(s)
  青木類
- Organizer
  The 35^<th> Annual Meeting of Japanese Society for Investigative Dermatology
- Place of Presentation
  和歌山
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells play a key role in host defense against lethal herpes simplex virus infectionhttp://sangaku.yamanashi.ac.jp/SearchResearcher/contents/77671D51402977B3.html2010
- Author(s)
  青木類
- Organizer
  Japanese Society for Investigative Dermatology
- Place of Presentation
  和歌山
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells play a key role in host defense against lethal herpes simplex virus infection2010
- Author(s)
  青木類
- Organizer
  40^<th> Annual European Society for Dermatological Research (ESDR) meeting
- Place of Presentation
  ヘルシンキ
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells regulate the cytokine microenvironment of the skin in herpes simplex virus infection2009
- Author(s)
  青木類
- Organizer
  The 34^<th> Annual Meeting of Japanese Society for Investigative Dermatology
- Place of Presentation
  福岡
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells regulate the cytokine microenvironment of the skin in herpes simplex virus infection2009
- Author(s)
  青木類
- Organizer
  Japanese Society for Investigative Dermatology
- Place of Presentation
  福岡
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells regulate the magnitude and the cytokine microenvironment in HSV infection2009
- Author(s)
  青木類
- Organizer
  European Society for Dermatological Reserch
- Place of Presentation
  ブダペスト(ハンガリー)
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] Mast cells regulate the cytokine microenvironment of the skin in herpes simplex virus infection2009
- Author(s)
  青木類
- Organizer
  39^<th> Annual European Society for Dermatological Research (ESDR) meeting
- Place of Presentation
  ブダペスト
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-21791068
[Presentation] The IL-33/ST2 axis on mast cells contributes to protective immune responses to herpes simplex virus-2
- Author(s)
  Rui Aoki, Tatsuyoshi Kawamura, Fumi Goshima, Youichi Ogawa, Susumu Nakae, Atsuhito Nakao and Shinji Shimada
- Organizer
  EMBRN-COST International Mast Cell and Basophil Meeting
- Place of Presentation
  Munich, Germany
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26461684
[Presentation] The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cell-mediated antiviral innate immunity
- Author(s)
  Rui Aoki, Tatsuyoshi Kawamura, Fumi Goshima, Youichi Ogawa, Susumu Nakae, Atsuhito Nakao and Shinji Shimada
- Organizer
  The 11th Meeting of the German-Japanese Society of Dermatology, post congress
- Place of Presentation
  Munich, Germany
- Year and Date
  2014-06-15 – 2014-06-16
- Data Source
  KAKENHI-PROJECT-26461684
[Presentation] The IL-33/ST2 axis on mast cells contributes to protective immune responses to herpes simplex virus-2
- Author(s)
  Rui Aoki, Tatsuyoshi Kawamura, Fumi Goshima, Youichi Ogawa, Susumu Nakae, Atsuhito Nakao and Shinji Shimada
- Organizer
  The 39th Annual meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府)
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26461684
[Presentation] The IL-33-ST2 pathway drives mast cell-dependent antiviral responses
- Author(s)
  Rui Aoki, Tatsuyoshi Kawamura, Fumi Goshima, Youichi Ogawa, Susumu Nakae, Atsuhito Nakao and Shinji Shimada
- Organizer
  44th Annual meeting of European Society for Dermatological Research
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26461684

1. SHIMADA Shinji (10114505)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. KAWAMURA Tatsuyoshi (70262657)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
3. MATSUE Hiroyuki (10250424)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. NAGASAKA Akiko (60377546)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. OGAWA Yoichi (20377542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. SHIBAGAKI Naotaka (40262662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NISHIYAMA Hiroyuki (60115615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 石丸かよ子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AOKI Rui 青木 類

Research Projects

Research Products

Co-Researchers

HSV感染防御におけるマスト細胞の役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of mast cells on host defense against lethal herpes simplex virus infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Examination of the participation in HIV infection of the VitaminD3 and HSV-2 using the humanized mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of mast cells on host defense against lethal herpes simplex virus infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ギャップ結合の免疫における役割の解明とその遮断による抗炎症剤/免疫抑制剤の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of mast cells on viral infection and mast cell-based immunotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IL-33とウイルス感染 皮膚ヘルペス感染におけるAlarminとしてのIL-33の重要性2015

Author(s)

Journal Title

Data Source

[Journal Article] IL-33とウイルス感染 皮膚ヘルペス感染におけるalarminとしてのIL-33の重要性2015

Author(s)

Journal Title

Data Source

[Journal Article] Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antimicrobial peptide LL-37 produced by HSV-2-infected keratinocytes enhances HIV infection of Langerhans cells2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antimicrobial Peptide LL-37 Produced by HSV-2-Infected Keratinocytes Enhances HIV Infection of Langerhans Cells2013

Author(s)

Journal Title

Data Source

[Journal Article] Oral administration of the CCR5 inhibitor , maraviroc, blocks HIV ex vivo infection of Langerhans cells within the epithelium2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mast cells play a key role in host defense against herpes simplex virus infection through TNF-α and IL-6 production2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mast Cells Play a Key Role in Host Defense against Herpes Simplex Virus Infection through TNF-α and IL-6 Production.2013

Author(s)

Journal Title

Data Source

[Journal Article] Mast cells play a key role in host defense against herpes simplex virus infection through TNF-α and IL-6 production2013

Author(s)

Journal Title

Data Source

AOKI Rui 青木類

[Journal Article] IL-33とウイルス感染皮膚ヘルペス感染におけるAlarminとしてのIL-33の重要性2015

[Journal Article] IL-33とウイルス感染　皮膚ヘルペス感染におけるalarminとしてのIL-33の重要性2015