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Usui Masanobu  臼井 正信

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USUI Masanobu  臼井 正信

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Researcher Number 10378341
Affiliation (Current) 2025: 藤田医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2016: 三重大学, 医学部附属病院, 准教授
2014 – 2015: 三重大学, 医学(系)研究科(研究院), 准教授
2012 – 2013: 三重大学, 医学(系)研究科(研究院), 講師
2008 – 2010: Mie University, 大学院・医学系研究科, 講師
Review Section/Research Field
Principal Investigator
General surgery
Keywords
Principal Investigator
テーラーメード治療 / C型肝炎 / B型肝炎 / 肝炎ウィルス / 肝移植 / カルシニューリンインヒビター / 遺伝子多型 / CYP3A5 / 生体肝移植
  • Research Projects

    (2 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (1 People)
  •  Tailor-made treatment for prevention of hepatitis after liver transplantation.Principal Investigator

    • Principal Investigator
      Usui Masanobu
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Mie University
  •  The influence based on CYP3A5 gene polymorphism for calcineurin inhibitors for tailor-made treatment after living-donor liver transplantation.Principal Investigator

    • Principal Investigator
      USUI Masanobu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Mie University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation Book

  • [Book] 重症患者と栄養管理Q&A-ICUにNSTがやってきた-2010

    • Author(s)
      臼井正信
    • Total Pages
      1656
    • Publisher
      総合医学者
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] Discontinuation of Hepatitis B Immunoglobulin by Long-term Hepatitis B Vaccine Inoculation in Preventing Hepatitis B Recurrence After Liver Transplantation.2016

    • Author(s)
      Usui M, Sugimoto K, Kato H, Murata Y, Tanemura A, Kuriyama N, Azumi Y, Kishiwada M, Mizuno S, Sakurai H, Takei Y, Isaji S.
    • Journal Title

      Transplant Proc

      Volume: 48 Issue: 4 Pages: 1179-1183

    • DOI

      10.1016/j.transproceed.2015.12.110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Journal Article] Hypertension and hepatitis C virus infection are strong risk factors for developing late renal dysfunction after living donor liver transplantation: significance of renal biopsy.2014

    • Author(s)
      Fujinaga K, Usui M, Yamamoto N, Ishikawa E, Nakatani A, Kishiwada M, Mizuno S, Sakurai H, Tabata M, Isaji S
    • Journal Title

      Transplant Proc. 2014 Apr;46(3):804-10. doi: 10.1016/j.transproceed.2013.11.103.

      Volume: 46 Pages: 804-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Journal Article] Hypertension and hepatitis C virus infection are strong risk factors for developing late renal dysfunction after living donor liver transplantation: significance of renal biopsy.2014

    • Author(s)
      Fujinaga K, Usui M, Yamamoto N, Ishikawa E, Nakatani A, Kishiwada M, Mizuno S, Sakurai H, Tabata M, Isaji S.
    • Journal Title

      Transplant Proc.

      Volume: 46 Pages: 804-810

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Journal Article] The long-term effects of splenectomy and subsequent interferon therapy in patients with HCV-related liver cirrhosis.2014

    • Author(s)
      Inagaki Y, Sugimoto K, Shiraki K, Tameda M, Kusagawa S, Nojiri K, Ogura S, Yamamoto N, Takei Y, Ito M, Mizuno S, Usui M, Sakurai H, Isaji S.
    • Journal Title

      Mol Med Rep.

      Volume: 9 Pages: 487-492

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Journal Article] Clinical features and treatment outcome of borderline resectable pancreatic head/body cancer: a multi-institutional survey by the Japanese Society of Pancreatic Surgery.2013

    • Author(s)
      Kato H, Usui M, Isaji S,et al
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: Mar 14. [Epub ahead of print] Issue: 2 Pages: 351-375

    • DOI

      10.1007/s002080100307

    • NAID

      10031194616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Journal Article] Behavior of ADAMTS13 and Von Willebrand factor levels in patients after living donor liver transplantation.2013

    • Author(s)
      Takahashi N, Wada H, Usui M,et al
    • Journal Title

      Thromb Res.

      Volume: 131(3) Issue: 3 Pages: 225-9

    • DOI

      10.1016/j.thromres.2012.12.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Journal Article] Immunological aspects in late phase of living donor liver transplant patients: usefulness of monitoring peripheral blood CD4+ adenosine triphosphate activity.2013

    • Author(s)
      Mizuno S, Muraki Y, Nakatani K, Tanemura A, Kuriyama N, Ohsawa I, Azumi Y, Kishiwada M, Usui M, Sakurai H, Tabata M, Yamamoto N, Yamada T, Shiraki K, Takei Y, Nobori T, Okuda M, Isaji S.
    • Journal Title

      Clin Dev Immunol

      Volume: 2013 Pages: 8-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Journal Article] Effect of a prostaglandin I(2) analog on the expression of thrombomodulin in liver and spleen endothelial cells after an extensive hepatectomy.2011

    • Author(s)
      Usui M, et al
    • Journal Title

      Surg Today

      Volume: 41 Pages: 230-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] 肝移植後のB型肝炎再発予防の現状-特にワクチン継続接種の効果-2011

    • Author(s)
      臼井正信、水野修吾、伊佐地秀司
    • Journal Title

      今日の移植 vol24

      Pages: 78-83

    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] 肝移植後のB型肝炎再発予防の現状-特にワクチン継続接種の効果-2011

    • Author(s)
      臼井正信、水野修吾、伊佐地秀司
    • Journal Title

      今日の移植

      Volume: 24 Pages: 78-83

    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] J Hepatobiliary Pancreat Sci.2011

    • Author(s)
      Mizuno S, Hamada T, Nakatani K, Kishiwada M, Usui M, Sakurai H, Tabata M, Sakamoto Y, Nishioka J, Muraki Y, Okuda M, Nobori T, Isaji S.
    • Journal Title

      18(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] Monitoring peripheral blood CD4+ adenosine triphosphate activity after living donor liver transplantation : impact of combination assays of immune function and CYP3A5 genotype.2011

    • Author(s)
      Mizuno S, Hamada T, Nakatani K, Kishiwada M, Usui M, et al
    • Journal Title

      J Hepatobiliary Pancreat Sci.

      Volume: 18 Pages: 226-34

    • NAID

      10029286381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] Effect of a prostaglandin I(2) analog on the expression of thrombomodulin in liver and spleen endothelial cells after an extensive hepatectomy.2010

    • Author(s)
      Usui M, Kuriyama N, Kisawada M, Hamada T, Mizuno S, Sakurai H, Tabata M, Isaji S.
    • Journal Title

      Surg.Today 41

      Pages: 230-236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] Tissue factor expression demonstrates severe sinusoidal endothelial cell damage during rejection after living-donorliver transplantation.2009

    • Author(s)
      Usui M, Kuriyama N, Kisawada M, Hamada T, Mizuno S, Sakurai H, Tabata M, Okamoto K, Uemoto S, Isaji S.
    • Journal Title

      JHepatobiliary Pancreat Surg 16

      Pages: 513-520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] Liver retransplantation with external biliary diversion for progressive familial intrahepatic cholestasis type 1 : a case report2009

    • Author(s)
      Masanibu Usui
    • Journal Title

      Pediatr Transplant 13

      Pages: 611-614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Journal Article] Tissue factor expression demonstrated severe sinusoidal endothelial cell damage during rejection after living-donor liver transplantation2009

    • Author(s)
      Masanobu Usui
    • Journal Title

      J Hepatobiliary Pancreat Surg 16

      Pages: 513-520

    • NAID

      10025139931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 肝移植後B型肝炎再発予防における,長期継続ワクチン接種によるHBIGからの離脱2015

    • Author(s)
      臼井正信,加藤宏之,村田泰洋,種村彰洋,栗山直久,安積良紀,岸和田昌之,水野修吾,櫻井洋至,伊佐地秀司
    • Organizer
      日本肝移植研究会
    • Place of Presentation
      ホテルオークラ神戸(兵庫県・神戸市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Presentation] Influence of angiotensin converting enzyme (ACE) genetic polymorphism on late renal dysfunction after adult-to-adult living donor liver transplantation2015

    • Author(s)
      Toshiki Matsui, Masanobu Usui, Kazuhisa Fujinaga, Kaname Nakatani, Yusuke Iizawa, Hiroyuki Kato, Akihiro Tanemura, Yasuhiro Murata, Yoshinori Azumi, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno, Hiroyuki Sakurai, Shuj Isaji
    • Organizer
      14th Congress of the Asian Society of Transplantation
    • Place of Presentation
      Singapore
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Presentation] Long-term influence of CYP3A5 gene polymorphism on pharmacokinetics of tacrolimus and patient outcome after living-donor liver transplantation2015

    • Author(s)
      Hiroyuki Kato, Masanobu Usui, Yuichi Muraki, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno, Hiroyuki Sakurai, Masami Tabata, Masahiro Okuda, Junji Nishioka, Kaname Nakatani, Tsutomu Nobori and Shuji Isaji
    • Organizer
      14th Congress of the Asian Society of Transplantation
    • Place of Presentation
      Singapore
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Presentation] Discontinuation of hepatitis B immunoglobulin by long-term hepatitis B vaccine inoculation in preventing hepatitis B recurrence after liver transplantation2015

    • Author(s)
      Masanobu Usui, Kazushi Sugimoto, Yasuhiro Murata, Akihiro Tanemura, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno, Hiroyuki Sakurai, Yoshiyuki Takei and Shuji Isaji
    • Organizer
      14th Congress of the Asian Society of Transplantation
    • Place of Presentation
      Singapore
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Presentation] Impact of an adjuvant hepatitis B vaccination after living donor liver transplantation for hepatitis B-related disease: treatment cost and weaning from hepatitis B hyperimmunoglobulin2013

    • Author(s)
      Usui M
    • Organizer
      第13会アジア移植学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Presentation] 生体肝移植後のC型肝炎再発に対するIFN治療の効果予測 ―特にHCV遺伝子変異、IL28B遺伝子多型についてー2012

    • Author(s)
      臼井 正信
    • Organizer
      日本肝移植研究会
    • Place of Presentation
      ホテル日航福岡
    • Data Source
      KAKENHI-PROJECT-24591876
  • [Presentation] タクロリムス持続静注による肝移植周術期管理-遺伝子多型の影響-2011

    • Author(s)
      臼井正信、村木優一、大倉康生、熊本幸司、岸和田昌之、大澤一郎、濱田賢司、水野修吾、櫻井洋至、田端正己、伊佐地秀司、奥田真弘
    • Organizer
      肝移植術後管理検討会
    • Place of Presentation
      京都
    • Year and Date
      2011-01-29
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] Thrombomodulin and Tenascin C levels in the blood are good predictive markers for the outcome after living donor liver transplantation2010

    • Author(s)
      Usui M, et al.
    • Organizer
      American Transplant Congress 2011
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] Thrombomodulin and Tenascin C levels in the blood are good predictive markers for the outcome after living donor liver transplantation.2010

    • Author(s)
      Usui M, Kuriyama N, Kisawada M, Hamada T, Mizuno S, Sakurai H, Tabata M, Isaji S
    • Organizer
      American Transplant Congress
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 大建中湯は生体肝移植後の門脈血流改善効果に加えbacterial translocation制御に有効か?2010

    • Author(s)
      臼井正信, 他
    • Organizer
      日本消化器外科学会
    • Place of Presentation
      下関
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 大建中湯は生体肝移植術後の門脈血流改善効果に加えbacterial translocation制御に有効か2010

    • Author(s)
      臼井正信、大倉康生、熊本幸司、岸和田昌之、大澤一郎、濱田賢司、水野修吾、櫻井洋至、田端正己、伊佐地秀司
    • Organizer
      日本消化器外科学会
    • Place of Presentation
      下関
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 遺伝子情報に基づいた生体肝移植における免疫抑制剤の最適化への取り組み2009

    • Author(s)
      臼井正信
    • Organizer
      第21回 日本肝胆膵外科学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-10
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 遺伝子情報に基づいた生体肝移植における免疫抑制剤の最適化への取り組み2009

    • Author(s)
      臼井正信、村木優一、大倉康生、熊本幸司、岸和田昌之、大澤一郎、濱田賢司、水野修吾、櫻井洋至、田端正己、伊佐地秀司
    • Organizer
      日本肝胆膵外科学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 肝移植後長期にわたるカルシニューリン・インヒビターに及ぼすCYP3A5遺伝子多型の影響2009

    • Author(s)
      臼井正信、大倉康生、熊本幸司、岸和田昌之、大澤一郎、濱田賢司、水野修吾、櫻井洋至、田端正己、伊佐地秀司
    • Organizer
      日本外科学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-04-08
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 肝移植後B型肝炎再発予防におけるHBワクチン継続接種の意義2009

    • Author(s)
      臼井正信
    • Organizer
      JDDW2009
    • Place of Presentation
      京都
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 肝移植後C型肝炎再発に対するIFN治療におけるHCV遺伝子変異の影響2009

    • Author(s)
      臼井正信
    • Organizer
      第27回 日本肝移植研究会
    • Place of Presentation
      三島
    • Year and Date
      2009-07-10
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] パネルディスカッション9肝移植後の長期成績と問題点.生体肝移植後の長期成績-C型肝炎再発に対するIFN治療の長期成績について-2009

    • Author(s)
      臼井正信、大倉康生、熊本幸司、岸和田昌之、大澤一郎、濱田賢司、水野修吾、櫻井洋至、田端正己、伊佐地秀司
    • Organizer
      日本消化器外科学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 生体肝移植後の長期成績-C型肝炎再発に対するIFN治療の長期成績について-2009

    • Author(s)
      臼井正信
    • Organizer
      第64回 日本消化器外科学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 遺伝子情報に基づいた肝移植における免疫抑制療法最適化への取り組み2009

    • Author(s)
      臼井正信
    • Organizer
      第27回 日本肝移植研究会
    • Place of Presentation
      三島
    • Year and Date
      2009-07-10
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 生体肝移植術後周術期侵襲に伴う類洞内皮障害と remodeling の検討2009

    • Author(s)
      臼井正信
    • Organizer
      第27回 日本肝移植研究会
    • Place of Presentation
      三島
    • Year and Date
      2009-07-10
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] Long-term influence of CYP3A5 donor/recipient polymorphism on the pharmacokinetics of calcineurin inhibitors in the recipients of living-donor liver transplantation2009

    • Author(s)
      Usui M, Muraki Y, Kato H, Kuriyama N, Kishiwada M, Mizuno S, Sakurai H, Tabata M, Okuda M, Nishioka J, Nakatani A, Nobori T, Isaji S
    • Organizer
      Transplant Congress
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-05-30
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] Long-term influence of CYP3A5 donor/recipient polymorphism on the pharmacokinetics of calcineurin inhibitors in the recipients of living-donor liver transplantation2009

    • Author(s)
      臼井正信
    • Organizer
      American Transplant Congress 2009
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2009-05-31
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 肝移植後拒絶反応に伴う類洞内皮障害と remodeling の検討-特に Tissue factor と Tenascin-C 発現について-2009

    • Author(s)
      臼井正信
    • Organizer
      第45回 日本移植学会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-16
    • Data Source
      KAKENHI-PROJECT-20591521
  • [Presentation] 遺伝子情報に基づいた生体肝移植のテーラーメード治療2008

    • Author(s)
      臼井正信
    • Organizer
      108回 日本外科学会
    • Place of Presentation
      長崎
    • Year and Date
      2008-05-14
    • Data Source
      KAKENHI-PROJECT-20591521
  • 1.  SUGIMOTO Kazushi (60378370)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results

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