Takehashi Masanori 竹橋正則

… Alternative Names

TAKEHASHI MASANORI 竹橋正則

TAKEHASHI Masanori 竹橋正則

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Researcher Number	10378862
Other IDs
Affiliation (Current)	2025: 神戸学院大学, 栄養学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 神戸学院大学, 栄養学部, 教授 2016 – 2022: 大阪大谷大学, 薬学部, 准教授 2012 – 2013: 大阪大谷大学, 薬学部, 准教授 2011: 大阪大谷大学, 薬学部, 講師 2007 – 2010: Osaka Ohtani University, Faculty of Pharmacy, 専任講師 2006: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / General anatomy (including Histology/Embryology) Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Food science
Keywords	Principal Investigator 精子幹細胞 / 再生医療 / 発生・分化 / ポリ(ADP-リボシル)化 / 多能性幹細胞 / PARP / PARP阻害剤 / 発生生物学 / 神経幹細胞 / genetics … More / development and differentiation / spermatogenesis / cell fusion / spermatogonial stem cells / 遺伝学 / 精子形成 / 細胞融合 / ポリ(ＡＤＰ-リボース) / ポリ(ADP-リボース） / ポリ(ADP-リボース) / ポリ(APD-リボシル)化 … More Except Principal Investigator セレンタンパク質 / 微量必須元素 / 受容体 / SELENOP / apoER2 / セレン / 2型糖尿病 / セレン輸送 / 一酸化窒素 / ApoER2 / セレノプロテインP / アポＥ受容体２ / シグナル伝達 / 血管内皮細胞 / アポリポプロテインE受容体２ / ２型糖尿病 / 糖尿病 / アポリポプロテインE / セレンタンパク質P / グルコース / セレノシステイン / アデノウイルス / アポリポプロテインＥ / apoE Less

Essential role of poly(ADP-ribosyl)ation in pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  竹橋正則
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kobe Gakuin University
  Osaka Ohtani University
The function of selenium transport proteins in endothelial cell signal transduction.
- Principal Investigator
  
  Kurokawa Suguru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka Ohtani University
Identification of novel poly(ADP-ribosyl)ated proteins in spermatogonial stem cellsPrincipal Investigator
- Principal Investigator
  
  TAKEHASHI MASANORI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka Ohtani University
Analysis of selenium-transport protein and apoER2 signaling in deterioration of type 2 diabetes
- Principal Investigator
  
  Kurokawa Suguru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Osaka Ohtani University
Essential role of poly(ADP-ribosyl)ation in maintenance of spermatogonial stem cellsPrincipal Investigator
- Principal Investigator
  
  TAKEHASHI MASANORI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka Ohtani University
Role of poly(ADP-ribosyl) ation in spermatogonial stem cellsPrincipal Investigator
- Principal Investigator
  
  TAKEHASHI Masanori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Otani Womens University
Functional analysis of spermatogonial stem cells by cell fusionPrincipal Investigator
- Principal Investigator
  
  TAKEHASHI Masanori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Otani Womens University
  Kyoto University

[Book] 幹細胞の分化誘導と応用-ES細胞・iPS細胞・体性幹細胞研究最前線-2009
- Author(s)
  竹橋正則, 篠原美都, 篠原隆司
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-20590076
[Book] 幹細胞の分化誘導と応用-ES細胞・iPS細胞・体性幹細胞研究最前線-(p. 35-44)2009
- Author(s)
  竹橋正則
- Total Pages
  612
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-20590076
[Book] 再生医療へ進む最先端の幹細胞研究(実験医学26巻5号(増刊))2008
- Author(s)
  竹橋正則
- Total Pages
  233
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590167
[Book] 再生医療へ進む最先端の幹細胞研究(編集/山中伸弥、中内啓光:実験医学Vol.26 No.5増刊)2008
- Author(s)
  竹橋正則
- Total Pages
  233
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Suppression of cell cycle progression by poly(ADP-ribose) polymerase inhibitor PJ34 in neural stem/progenitor cells.2019
- Author(s)
  Kurokawa S, Okuda A, Nishizawa Y, Furukawa K, Sumihiro A, Nakaji Y, Tanaka S, Takehashi M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 510 Issue: 1 Pages: 59-64
- DOI
  10.1016/j.bbrc.2019.01.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08257
[Journal Article] Identification of transcriptional regulatory elements of the poly(ADP-ribose) polymerase-1 gene in neural stem/progenitor cells.2019
- Author(s)
  Kurokawa S, Okuda A, Kondo Y, Tanaka S, Takehashi M
- Journal Title
  
  Int J Anal Bio-Sci
  
  Volume: 7 Pages: 6-13
- NAID
  40021857006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08257
[Journal Article] Poly(ADP-ribose) Polymerase Inhibitors Activate the p53 Signaling Pathway in Neural Stem/Progenitor Cells.2017
- Author(s)
  Okuda, A., Kurokawa, S., Takehashi, M., Maeda, A., Fukuda, K., Kubo, Y., Nogusa, H., Takatani-Nakase, T., Okuda, S., Ueda, K., Tanaka, S.
- Journal Title
  
  BMC Neurosci.
  
  Volume: 18 Issue: 1 Pages: 14-14
- DOI
  10.1186/s12868-016-0333-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-15K07955, KAKENHI-PROJECT-16K08257
[Journal Article] Tissue-specific transport mechanism of selenium2016
- Author(s)
  Suguru Kurokawa, Seigo Tanaka and Masanori Takehashi
- Journal Title
  
  Journal of Analytical Bio-Science
  
  Volume: 39 Pages: 217-225
- NAID
  40020983472
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K18708
[Journal Article] Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice2012
- Author(s)
  Takehashi M, Tada M, Kanatsu-Shinohara M, Morimoto H, Kazuki Y, Oshimura M, Tada T, Shinohara T
- Journal Title
  
  Biol Reprod
  
  Volume: 86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590097
[Journal Article] Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in Mice2012
- Author(s)
  Takehashi, M., Tada, M., Kanatsu-Shinohara, M., Morimoto, H., Kazuki, Y., Oshimura, M., Tada, T. and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 86(6) Issue: 6 Pages: 178-178
- DOI
  10.1095/biolreprod.112.098988
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006, KAKENHI-PUBLICLY-23013014, KAKENHI-PROJECT-23390067, KAKENHI-PROJECT-23590097
[Journal Article] Mammalian selenocysteine lyase is involved in selenoprotein biosynthesis2011
- Author(s)
  Kurokawa S, Takehashi M, Tanaka H, Mihara H, Kurihara T, Tanaka S, Hill K, Burk R, Esaki N
- Journal Title
  
  J Nutr Sci Vitaminol (Tokyo)
  
  Volume: 57 Pages: 298-305
- NAID
  130001373002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590097
[Journal Article] Inhibition of poly(ADP-ribose) polymerase-1 attenuates the toxicity of carbon tetrachloride2011
- Author(s)
  Banasik M, Stedeford T, Strosznajder RP, Takehashi M, Tanaka S, Ueda K
- Journal Title
  
  J Enzyme Inhib Med Chem
  
  Volume: 26 Pages: 883-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590097
[Journal Article] Mammalian selenocysteine lyase is involved in selenoprotein biosynthesis2011
- Author(s)
  Kurokawa S, Takehashi M, Tanaka H, Mihara H, Kurihara T, Tanaka S, Hill K, Burk R, Esaki N
- Journal Title
  
  J Nutr Sci Vitaminol
  
  Volume: 57 Pages: 298-305
- NAID
  130001373002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590076
[Journal Article] Inhibition of poly(ADP-ribose) polymerase-1 attenuates the toxicity of carbon tetrachloride2011
- Author(s)
  Banasik M, Stedeford T, Strosznajder RP, Takehashi M, Tanaka S, Ueda K
- Journal Title
  
  J Enzyme Inhib Med Chem
  
  Volume: 26 Pages: 883-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590076
[Journal Article] Generation of genetically modified animals using spermatogonial stem cells2010
- Author(s)
  竹橋正則
- Journal Title
  
  Development, Growth & Differentiation 52
  
  Pages: 303-310
- NAID
  10027564378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590076
[Journal Article] Generation of genetically modified animals using spermatogonial stem cells2010
- Author(s)
  Takehashi M, Kanatsu-Shinohara M, Shinohara T
- Journal Title
  
  Dev Growth Differ
  
  Volume: 52 Pages: 303-10
- NAID
  10027564378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590076
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects2009
- Author(s)
  Takashima S, Takehashi M, Lee J, Chuma S, Okano M, Hata K, Suetake I, Nakatsuji N, Miyoshi H, Tajima S, Tanaka Y, Toyokuni S, Sasaki H, Kanatsu-Shinohara M, Shinohara T
- Journal Title
  
  Biol Reprod
  
  Volume: 81 Pages: 155-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590076
[Journal Article] 精子幹細胞と再生医療2009
- Author(s)
  竹橋正則
- Journal Title
  
  産科と婦人科 76
  
  Pages: 1250-1254
- Data Source
  KAKENHI-PROJECT-20590076
[Journal Article] 精子幹細胞と再生医療2009
- Author(s)
  竹橋正則, 篠原美都, 篠原隆司
- Journal Title
  
  産科と婦人科
  
  Volume: 76 Pages: 1250-1254
- Data Source
  KAKENHI-PROJECT-20590076
[Journal Article] The development of new strategies for genetic modification using spermatogonial stem cells.2008
- Author(s)
  Takehashi, M, et al.
- Journal Title
  
  Experimental Medicine 26(5)
  
  Pages: 649-654
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Production of knockout mice by gene targeting in multipotent germlinestem cells2007
- Author(s)
  Takehashi, M., et. al.
- Journal Title
  
  Developmental Biology 312
  
  Pages: 344-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Adenovirus-mediated gene delivery into mouse spermatogonial stem cells2007
- Author(s)
  Takehashi M, Kanatsu-Shinohara M, Inoue K, Ogonuki N, Miki H, Toyokuni S, Ogura A, Shinohara T
- Journal Title
  
  Proc Natl Acad Sci U S A 104(8)
  
  Pages: 2596-2601
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Production of knockout mice by gene targeting in multipotent germline stem cells2007
- Author(s)
  Takehashi, M
- Journal Title
  
  Dev Biol 312
  
  Pages: 344-352
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Production of knockout mice by gene targeting in multipotent germline stem cells2007
- Author(s)
  Takehashi, M, et al.
- Journal Title
  
  Dev. Biol 312(1)
  
  Pages: 344-352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Adenovirus-mediated gene delivery into mouse spermatogonial stem cells2007
- Author(s)
  Takehashi, M
- Journal Title
  
  Proc Natl Acad Sci USA 104
  
  Pages: 2596-2601
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Adenovirus-mediated gene delivery into mouse spermatogonial stem cells.2007
- Author(s)
  Takehashi, M, et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A. 104(8)
  
  Pages: 2596-2601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination2006
- Author(s)
  Shinohara T, Kato M, Takehashi M, Lee J, Chuma S, Nakatsuji N, Kanatsu-Shinohara M, Hirabayashi M
- Journal Title
  
  Proc Natl Acad Sci U S A 103(37)
  
  Pages: 13624-13628
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells2006
- Author(s)
  Kanatsu-Shinohara M, Ikawa M, Takehashi M, et al.
- Journal Title
  
  Proc Natl Acad Sci U S A 103(21)
  
  Pages: 8018-8023
- Data Source
  KAKENHI-PROJECT-18590167
[Journal Article] Clonal origin of germ cell colonies after spermatogonial transplantation in mice2006
- Author(s)
  Kanatsu-Shinohara M, Inoue K, Miki H, Ogonuki N, Takehashi M, Morimoto T, Ogura A, Shinohara T
- Journal Title
  
  Biol Reprod 75(1)
  
  Pages: 68-74
- Data Source
  KAKENHI-PROJECT-18590167
[Presentation] セレンタンパク質Pとアポリポタンパク質E受容体２の結合解析2022
- Author(s)
  黒川優、竹橋正則、堀田紀久子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11782
[Presentation] Identification of important amino acid residues of ApoER2 for SELENOP binding2021
- Author(s)
  志賀友美, 竹橋正則, 堀田紀久子, 黒川優
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11782
[Presentation] セレノプロテインＰによる血管内皮細胞のシグナル伝達調節2020
- Author(s)
  黒川優, 竹橋正則
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-19K11782
[Presentation] ポリ(ADP-リボース)合成酵素阻害剤PJ34の神経幹細胞の細胞周期抑制作用について2018
- Author(s)
  黒川優、奥田明子、竹橋正則、田中静吾
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08257
[Presentation] ポリ(ADP-リボシル)化の抑制が精子幹細胞に与える影響2014
- Author(s)
  小野友久，中嶋瀬里奈，奥田明子，田中静吾，竹橋正則
- Organizer
  薬学会134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590097
[Presentation] 多能性精子幹細胞の初期化能の解析2014
- Author(s)
  中嶋瀬里奈，片山健太郎，奥田明子，田中静吾，竹橋正則
- Organizer
  薬学会134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590097
[Presentation] PARP-1による神経幹細胞の増殖制御2014
- Author(s)
  奥田明子，竹橋正則，田中静吾
- Organizer
  薬学会134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590097
[Presentation] 神経幹細胞の細胞周期にPARP阻害剤が与える影響2011
- Author(s)
  奥田明子, 竹橋正則, 他
- Organizer
  日本薬学会第131年会
- Place of Presentation
  年会要旨集
- Data Source
  KAKENHI-PROJECT-20590076
[Presentation] 精子幹細胞の培養とその可能性2009
- Author(s)
  竹橋正則
- Organizer
  第102回日本繁殖生物学会大会ワークショップ
- Place of Presentation
  近畿大学農学部(奈良市)
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-20590076
[Presentation] 多能性精子幹細胞を用いたノックアウトマウスの作製2008
- Author(s)
  竹橋正則
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590167
[Presentation] Production of knockout mice by gene targeting in multipotent germline stem cells.2008
- Author(s)
  Takehashi, M, et al.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590167

1. Kurokawa Suguru (70759761)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. TANAKA Seigo (70263150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. McDonald W. Hayes

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 篠原隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 奥田修二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takehashi Masanori 竹橋 正則

TAKEHASHI MASANORI 竹橋 正則

TAKEHASHI Masanori 竹橋 正則

Research Projects

Research Products

Co-Researchers

Essential role of poly(ADP-ribosyl)ation in pluripotent stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The function of selenium transport proteins in endothelial cell signal transduction.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel poly(ADP-ribosyl)ated proteins in spermatogonial stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of selenium-transport protein and apoER2 signaling in deterioration of type 2 diabetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Essential role of poly(ADP-ribosyl)ation in maintenance of spermatogonial stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of poly(ADP-ribosyl) ation in spermatogonial stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of spermatogonial stem cells by cell fusionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 幹細胞の分化誘導と応用-ES細胞・iPS細胞・体性幹細胞研究最前線-2009

Author(s)

Publisher

Data Source

[Book] 幹細胞の分化誘導と応用-ES細胞・iPS細胞・体性幹細胞研究最前線-(p. 35-44)2009

Author(s)

Total Pages

Publisher

Data Source

[Book] 再生医療へ進む最先端の幹細胞研究(実験医学26巻5号(増刊))2008

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] 再生医療へ進む最先端の幹細胞研究(編集/山中伸弥、中内啓光:実験医学Vol.26 No.5増刊)2008

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Suppression of cell cycle progression by poly(ADP-ribose) polymerase inhibitor PJ34 in neural stem/progenitor cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of transcriptional regulatory elements of the poly(ADP-ribose) polymerase-1 gene in neural stem/progenitor cells.2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Poly(ADP-ribose) Polymerase Inhibitors Activate the p53 Signaling Pathway in Neural Stem/Progenitor Cells.2017

Author(s)

Takehashi Masanori 竹橋正則

TAKEHASHI MASANORI 竹橋正則

TAKEHASHI Masanori 竹橋正則