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Homma Koichiro  本間 康一郎

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HOMMA Koichiro  本間 康一郎

本間 康一郎  ホンマ コウイチロウ

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Researcher Number 10383762
Other IDs
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 准教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 慶應義塾大学, 医学部(信濃町), 准教授
2016 – 2023: 慶應義塾大学, 医学部(信濃町), 講師
2013 – 2015: 慶應義塾大学, 医学部, 講師
2009 – 2012: Keio University, 医学部, 助教
2005 – 2006: 慶應義塾大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Basic Section 55060:Emergency medicine-related / Emergency medicine
Except Principal Investigator
Basic Section 55060:Emergency medicine-related / Basic Section 52010:General internal medicine-related
Keywords
Principal Investigator
ヒトES細胞 / 慢性腎臓病 / ヒトiPS細胞 / ニコチンアミドアデニンジヌクレオチド / 心停止蘇生後症候群 / 心停止後症候群 / サロゲートマーカー / 急性腎障害 / リプログライング / リプログラミング … More / ダイレクトリプログラミング / 腎臓構成細胞 / 尿細管上皮細胞 / 糸球体内皮細胞 / 尿細管細胞 / 内皮細胞 / 抗加齢因子 / ヒトES・iPS細胞 / microRNA / 低酸素 / 血管内皮細胞 / アデノシン / nNOS / 尿細管糸球体フィードバック / 腎輸入細動脈 / 糸球体過剰ろ過 / AMPキナーゼ / Rhoキナーゼ / 筋原性収縮反応 / 腎微小循環 … More
Except Principal Investigator
幹細胞培養上清液 / ラット / 出血性ショックモデル / 水素ガス / 免疫チェックポイント / 免疫調整療法 / バイオバンク / 心停止蘇生後 / オミクス解析 / 心停止後症候群 / 心停止症候群 / 2型糖尿病 / 脂肪組織 / 血管内皮細胞NAD(+)合成系 / 肥満 / インスリン抵抗性 / NMN / 老化 / NAD(+)中間代謝産物 / 血管内皮細胞 / NAD(+)合成系 / NAMPT / 造影剤腎症 / 急性腎障害 Less
  • Research Projects

    (13 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (16 People)
  •  心停止蘇生後患者のバイオバンクを機転とするリバーストランスレーショナル・リサーチ

    • Principal Investigator
      佐々木 淳一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Keio University
  •  Usefulness of hydrogen gas inhalation during transfusion resuscitation in rats with hemorrhagic shock

    • Principal Investigator
      矢島 慶太郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Keio University
  •  間葉系幹細胞培養上清液による幹細胞増殖を介した急性期臓器虚血再灌流障害の治療開発

    • Principal Investigator
      山元 良
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Keio University
  •  Development of a Novel Treatment Targeting the NAD Synthesis Pathway for Post-Cardiac Arrest Syndrome and Elucidation of Its Role in Severe Disease StatesPrincipal Investigator

    • Principal Investigator
      本間 康一郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Keio University
  •  脂肪組織血管新生能を標的とした血管内皮NAD賦活化による肥満2型糖尿病発症予防

    • Principal Investigator
      山口 慎太郎
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Keio University
  •  Elucidating the Pathophysiology of Post-Cardiac Arrest Syndrome and Developing Novel Therapies through Omics Analysis

    • Principal Investigator
      Sasaki Jinichi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Keio University
  •  Development of new therapeutic agents for acute kidney injuryPrincipal Investigator

    • Principal Investigator
      Homma Koichiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Keio University
  •  Clarification of the mechanism of acute kidney injury by administration of contrast media and pharmaceutical application

    • Principal Investigator
      Sasaki Junichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Keio University
  •  Direct induction of dermal fibroblasts via reprogramming of subcutaneous adipocytesPrincipal Investigator

    • Principal Investigator
      Homma Koichiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Keio University
  •  Generation of kidney tubular cells from human pluripotent stem cellsPrincipal Investigator

    • Principal Investigator
      Homma Koichiro
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Keio University
  •  Clarification of new pathological mechanisms for chronic kidney disease using technology that induces endothelial cells from human ES/iPS cellsPrincipal Investigator

    • Principal Investigator
      HOMMA Koichiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Keio University
  •  human ES・iPS-derived endothelial cells for chronic kidney diseasePrincipal Investigator

    • Principal Investigator
      HOMMA Koichiro
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Keio University
  •  腎微小循環におけるRhoキナーゼの役割およびその分子機構の検討Principal Investigator

    • Principal Investigator
      本間 康一郎
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Keio University

All 2022 2019 2016 2013 2010

All Journal Article Presentation

  • [Journal Article] Intestinal epithelial NAD(+) biosynthesis regulates GLP-1 production and postprandial glucose metabolism in mice2022

    • Author(s)
      Nagahisa Taichi, Yamaguchi Shintaro, Kosugi Shotaro, Homma Koichiro, Miyashita Kazutoshi, Irie Junichiro, Yoshino Jun, Itoh Hiroshi
    • Journal Title

      Endocrinology

      Volume: 163 Issue: 4 Pages: 1-12

    • DOI

      10.1210/endocr/bqac023

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07377, KAKENHI-PROJECT-21K08584, KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-20K23382, KAKENHI-PROJECT-20H00535
  • [Journal Article] Hydrogen gas and preservation of intestinal stem cells in mesenteric ischemia and reperfusion.2022

    • Author(s)
      Yamamoto R, Suzuki S, Homma K, Yamaguchi S, Sujino T, Sasaki J.
    • Journal Title

      World J Gastrointest Surg.

      Volume: 14(12) Issue: 12 Pages: 1329-1339

    • DOI

      10.4240/wjgs.v14.i12.1329

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07377, KAKENHI-PROJECT-22K16631, KAKENHI-PROJECT-20K17873
  • [Journal Article] Hydrogen gas distribution in organs after inhalation: Real-time monitoring of tissue hydrogen concentration in rat2019

    • Author(s)
      Yamamoto Ryo、Homma Koichiro、Suzuki Sayuri、Sano Motoaki、Sasaki Junichi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 1255-1255

    • DOI

      10.1038/s41598-018-38180-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08899
  • [Journal Article] Generation of kidney tubular organoids from human pluripotent stem cells2016

    • Author(s)
      Yamaguchi S, Morizane R, Homma K, Monkawa T, Suzuki S, Fujii S, Koda M, Hiratsuka K, Yamashita M, Yoshida T, Wakino S, Hayashi K, Sasaki J, Hori S, Itoh H
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 38353-38353

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461231
  • [Journal Article] Human ES-and iPS-derived vascular endothelial cells show greater functionality than adult endothelial cells due to greater expression of Sirt1.2010

    • Author(s)
      Homma K, 他10名
    • Journal Title

      Atherosclerosis. 212

      Pages: 42-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790805
  • [Journal Article] Human ES- and iPS-derived vascular endothelial cells show greater functionality than adult endothelial cells due to greater expression of Sirt12010

    • Author(s)
      Homma K, et.al.
    • Journal Title

      Atherosclerosis

      Volume: 212 Pages: 42-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790805
  • [Presentation] The role of intestinal NAMPT-mediated NAD+ biosynthesis in whole-body energy and glucose metabolism.2022

    • Author(s)
      Yamaguchi S, Nagahisa T, Kosugi S, Nishioka K, Watanabe Y, Homma K, Miyashita K, Irie J, Yoshino J, Itoh H.
    • Organizer
      The 29th Scientific Meeting of the International Society of Hypertension (Japan・Kyoto)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07377
  • [Presentation] Vascular endothelial NAMPT-mediated NAD+ biosynthesis regulates whole-body blood pressure and insulin resistance.2022

    • Author(s)
      Kosugi S, Yamaguchi S, Homma K, Nagahisa T, Nishioka K, Watanabe Y, Kinouchi K, Hayashi K, Miyashita K, Kanda T, Irie J, Yoshino J, Itoh H.
    • Organizer
      The 29th Scientific Meeting of the International Society of Hypertension (Japan・Kyoto)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07377
  • [Presentation] ヒトES細胞を用いた尿細管上皮細胞の分化誘導の試み2013

    • Author(s)
      山口慎太郎、本間康一郎、門川俊明、森実隆司、鈴木さゆり、藤井静花、脇野修、林晃一、伊藤裕
    • Organizer
      第56回日本腎臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2013-05-10
    • Data Source
      KAKENHI-PROJECT-23790953
  • 1.  Sasaki Junichi (90235250)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  YAMAGUCHI Shintaro (50464855)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 3.  SUZUKI Sayuri (90445445)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  多村 知剛 (00571720)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  家田 真樹 (70296557)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  村岡 直人 (70528728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  佐野 元昭 (30265798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  遠山 周吾 (90528192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  木内 謙一郎 (50528578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  武林 亨 (30265780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  矢島 慶太郎 (20991285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  松岡 義 (70649938)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  山川 一馬 (50597507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  山元 良 (90528853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  吉野 純 (80383777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TOYOSAKI Mitsunobu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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