Homma Koichiro 本間康一郎

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HOMMA Koichiro 本間康一郎

本間康一郎ホンマコウイチロウ

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Researcher Number	10383762
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 慶應義塾大学, 医学部(信濃町), 准教授 2016 – 2023: 慶應義塾大学, 医学部(信濃町), 講師 2013 – 2015: 慶應義塾大学, 医学部, 講師 2009 – 2012: Keio University, 医学部, 助教 2005 – 2006: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 55060:Emergency medicine-related / Emergency medicine Except Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator ヒトES細胞 / 慢性腎臓病 / ヒトiPS細胞 / ニコチンアミドアデニンジヌクレオチド / 心停止蘇生後症候群 / 心停止後症候群 / サロゲートマーカー / 急性腎障害 / リプログライング / リプログラミング … More / ダイレクトリプログラミング / 腎臓構成細胞 / 尿細管上皮細胞 / 糸球体内皮細胞 / 尿細管細胞 / 内皮細胞 / 抗加齢因子 / ヒトES・iPS細胞 / microRNA / 低酸素 / 血管内皮細胞 / アデノシン / nNOS / 尿細管糸球体フィードバック / 腎輸入細動脈 / 糸球体過剰ろ過 / AMPキナーゼ / Rhoキナーゼ / 筋原性収縮反応 / 腎微小循環 … More Except Principal Investigator 水素ガス / ARDS / 幹細胞培養上清液 / ラット / 出血性ショックモデル / 免疫チェックポイント / 免疫調整療法 / バイオバンク / 心停止蘇生後 / オミクス解析 / 心停止後症候群 / 心停止症候群 / 2型糖尿病 / 脂肪組織 / 血管内皮細胞NAD(+)合成系 / 肥満 / インスリン抵抗性 / NMN / 老化 / NAD(+)中間代謝産物 / 血管内皮細胞 / NAD(+)合成系 / NAMPT / 造影剤腎症 / 急性腎障害 Less

ブタ敗血症性ARDS・DICにおける水素ガス吸入の呼吸機能障害、凝固能障害の改善効果
- Principal Investigator
  
  松岡義
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
心停止蘇生後患者のバイオバンクを機転とするリバーストランスレーショナル・リサーチ
- Principal Investigator
  
  佐々木淳一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
Usefulness of hydrogen gas inhalation during transfusion resuscitation in rats with hemorrhagic shock
- Principal Investigator
  
  矢島慶太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
間葉系幹細胞培養上清液による幹細胞増殖を介した急性期臓器虚血再灌流障害の治療開発
- Principal Investigator
  
  山元良
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
Development of a Novel Treatment Targeting the NAD Synthesis Pathway for Post-Cardiac Arrest Syndrome and Elucidation of Its Role in Severe Disease StatesPrincipal Investigator
- Principal Investigator
  
  本間康一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
脂肪組織血管新生能を標的とした血管内皮NAD賦活化による肥満2型糖尿病発症予防
- Principal Investigator
  
  山口慎太郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Keio University
Elucidating the Pathophysiology of Post-Cardiac Arrest Syndrome and Developing Novel Therapies through Omics Analysis
- Principal Investigator
  
  Sasaki Jinichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
Development of new therapeutic agents for acute kidney injuryPrincipal Investigator
- Principal Investigator
  
  Homma Koichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
Clarification of the mechanism of acute kidney injury by administration of contrast media and pharmaceutical application
- Principal Investigator
  
  Sasaki Junichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Keio University
Direct induction of dermal fibroblasts via reprogramming of subcutaneous adipocytesPrincipal Investigator
- Principal Investigator
  
  Homma Koichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Keio University
Generation of kidney tubular cells from human pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  Homma Koichiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Clarification of new pathological mechanisms for chronic kidney disease using technology that induces endothelial cells from human ES/iPS cellsPrincipal Investigator
- Principal Investigator
  
  HOMMA Koichiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
human ES・iPS-derived endothelial cells for chronic kidney diseasePrincipal Investigator
- Principal Investigator
  
  HOMMA Koichiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
腎微小循環におけるRhoキナーゼの役割およびその分子機構の検討Principal Investigator
- Principal Investigator
  
  本間康一郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University

All 2022 2019 2016 2013 2010

All Journal Article Presentation

[Journal Article] Intestinal epithelial NAD(+) biosynthesis regulates GLP-1 production and postprandial glucose metabolism in mice2022
- Author(s)
  Nagahisa Taichi, Yamaguchi Shintaro, Kosugi Shotaro, Homma Koichiro, Miyashita Kazutoshi, Irie Junichiro, Yoshino Jun, Itoh Hiroshi
- Journal Title
  
  Endocrinology
  
  Volume: 163 Issue: 4 Pages: 1-12
- DOI
  10.1210/endocr/bqac023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07377, KAKENHI-PROJECT-21K08584, KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-20K23382, KAKENHI-PROJECT-20H00535
[Journal Article] Hydrogen gas and preservation of intestinal stem cells in mesenteric ischemia and reperfusion.2022
- Author(s)
  Yamamoto R, Suzuki S, Homma K, Yamaguchi S, Sujino T, Sasaki J.
- Journal Title
  
  World J Gastrointest Surg.
  
  Volume: 14(12) Issue: 12 Pages: 1329-1339
- DOI
  10.4240/wjgs.v14.i12.1329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07377, KAKENHI-PROJECT-22K16631, KAKENHI-PROJECT-20K17873
[Journal Article] Hydrogen gas distribution in organs after inhalation: Real-time monitoring of tissue hydrogen concentration in rat2019
- Author(s)
  Yamamoto Ryo、Homma Koichiro、Suzuki Sayuri、Sano Motoaki、Sasaki Junichi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1255-1255
- DOI
  10.1038/s41598-018-38180-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08899
[Journal Article] Generation of kidney tubular organoids from human pluripotent stem cells2016
- Author(s)
  Yamaguchi S, Morizane R, Homma K, Monkawa T, Suzuki S, Fujii S, Koda M, Hiratsuka K, Yamashita M, Yoshida T, Wakino S, Hayashi K, Sasaki J, Hori S, Itoh H
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 38353-38353
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461231
[Journal Article] Human ES-and iPS-derived vascular endothelial cells show greater functionality than adult endothelial cells due to greater expression of Sirt1.2010
- Author(s)
  Homma K, 他10名
- Journal Title
  
  Atherosclerosis. 212
  
  Pages: 42-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790805
[Journal Article] Human ES- and iPS-derived vascular endothelial cells show greater functionality than adult endothelial cells due to greater expression of Sirt12010
- Author(s)
  Homma K, et.al.
- Journal Title
  
  Atherosclerosis
  
  Volume: 212 Pages: 42-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790805
[Presentation] The role of intestinal NAMPT-mediated NAD+ biosynthesis in whole-body energy and glucose metabolism.2022
- Author(s)
  Yamaguchi S, Nagahisa T, Kosugi S, Nishioka K, Watanabe Y, Homma K, Miyashita K, Irie J, Yoshino J, Itoh H.
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension (Japan・Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07377
[Presentation] Vascular endothelial NAMPT-mediated NAD+ biosynthesis regulates whole-body blood pressure and insulin resistance.2022
- Author(s)
  Kosugi S, Yamaguchi S, Homma K, Nagahisa T, Nishioka K, Watanabe Y, Kinouchi K, Hayashi K, Miyashita K, Kanda T, Irie J, Yoshino J, Itoh H.
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension (Japan・Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07377
[Presentation] ヒトES細胞を用いた尿細管上皮細胞の分化誘導の試み2013
- Author(s)
  山口慎太郎、本間康一郎、門川俊明、森実隆司、鈴木さゆり、藤井静花、脇野修、林晃一、伊藤裕
- Organizer
  第56回日本腎臓学会総会
- Place of Presentation
  東京
- Year and Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-23790953

1. Sasaki Junichi (90235250)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. YAMAGUCHI Shintaro (50464855)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. 多村知剛 (00571720)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SUZUKI Sayuri (90445445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 松岡義 (70649938)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 山川一馬 (50597507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 家田真樹 (70296557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 村岡直人 (70528728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐野元昭 (30265798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 遠山周吾 (90528192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 木内謙一郎 (50528578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 武林亨 (30265780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 矢島慶太郎 (20991285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山元良 (90528853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 吉野純 (80383777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOYOSAKI Mitsunobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Homma Koichiro 本間 康一郎

HOMMA Koichiro 本間 康一郎

本間 康一郎 ホンマ コウイチロウ

Research Projects

Research Products

Co-Researchers

ブタ敗血症性ARDS・DICにおける水素ガス吸入の呼吸機能障害、凝固能障害の改善効果

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心停止蘇生後患者のバイオバンクを機転とするリバーストランスレーショナル・リサーチ

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Usefulness of hydrogen gas inhalation during transfusion resuscitation in rats with hemorrhagic shock

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

間葉系幹細胞培養上清液による幹細胞増殖を介した急性期臓器虚血再灌流障害の治療開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a Novel Treatment Targeting the NAD Synthesis Pathway for Post-Cardiac Arrest Syndrome and Elucidation of Its Role in Severe Disease StatesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脂肪組織血管新生能を標的とした血管内皮NAD賦活化による肥満2型糖尿病発症予防

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the Pathophysiology of Post-Cardiac Arrest Syndrome and Developing Novel Therapies through Omics Analysis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new therapeutic agents for acute kidney injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of the mechanism of acute kidney injury by administration of contrast media and pharmaceutical application

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Direct induction of dermal fibroblasts via reprogramming of subcutaneous adipocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of kidney tubular cells from human pluripotent stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of new pathological mechanisms for chronic kidney disease using technology that induces endothelial cells from human ES/iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

human ES・iPS-derived endothelial cells for chronic kidney diseasePrincipal Investigator

Principal Investigator

Homma Koichiro 本間康一郎

HOMMA Koichiro 本間康一郎

本間康一郎ホンマコウイチロウ