Iwamoto Junichi 岩本淳一

… Alternative Names

IWAMOTO JUNICHI 岩本淳一

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Researcher Number	10384950
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 東京医科大学, 医学部, 教授 2020: 東京医科大学, 医学部, 教授 2012 – 2019: 東京医科大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 53010:Gastroenterology-related / Eating habits / Integrated Nutrition Science Except Principal Investigator Basic Section 49030:Experimental pathology-related / Gastroenterology
Keywords	Principal Investigator 胆汁酸 / 低用量アスピリン / 小腸粘膜障害 / サリチル酸(SA) / 小腸粘膜傷 / アスピリン / Clostridium difficile 腸炎 / Clostridium XIVa / CD 関連下痢症 / CD-associated diarrhea … More / Clostridium difficile / 胆汁酸代謝 / クロストリジウム・ディフィシル / 糖代謝 / アミノ酸代謝 / 脂肪酸代謝 / 低栄養 / 脂肪肝 / 低栄養性脂肪肝 / CYP3A4 / LC-MS/MS / 小腸機能 / クローン病 … More Except Principal Investigator 胆汁酸 / 肝細胞癌 / 非アルコール性脂肪肝炎 / 非アルコール性脂肪肝 / マウスモデル / 胆汁酸代謝 / 消化器病学 / Cyp2a12 / Cyp2c70 / ノックアウトマウス Less

低用量アスピリンによる小腸粘膜障害発症メカニズムの解明とリスク予測法の開発Principal Investigator
- Principal Investigator
  
  岩本淳一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo Medical University
胆汁酸ヒト化マウスを用いたNAFL/NASH/HCC進展メカニズムの解明
- Principal Investigator
  
  本多彰
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo Medical University
Serum bile acid analysis of patients with Clostridium difficile -associated diarrheaPrincipal Investigator
- Principal Investigator
  
  Iwamoto Junichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical University
Production and phenotype analysis of mouse models with humanized bile acid composition
- Principal Investigator
  
  Honda Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical University
Serum metabolomics analysis of patients with fatty liver due to undernutritionPrincipal Investigator
- Principal Investigator
  
  Iwamoto Junichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Tokyo Medical University
Development of new biomarkers for small intestinal malabsorptionPrincipal Investigator
- Principal Investigator
  
  IWAMOTO JUNICHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Tokyo Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] Background factors of idiopathic peptic ulcers and optimal treatment methods: a multicenter retrospective Japanese study2024
- Author(s)
  Noriyuki Nakajima, Toshihisa Takeuchi, Junichi Iwamoto
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 74 Issue: 1 Pages: 82-89
- DOI
  10.3164/jcbn.23-82
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06620, KAKENHI-PROJECT-21H03369
[Journal Article] 西欧食による腸内細菌叢と胆汁酸代謝への影響2023
- Author(s)
  岩本淳一、宮崎照雄、本多彰
- Journal Title
  
  消化と吸収
  
  Volume: 45 Pages: 119-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06620
[Journal Article] Evaluation of the risk of Clostridium difficile infection using a serum bile acid profile2022
- Author(s)
  Monma T, Iwamoto J, Honda A, Ueda H, Kakizaki F, Yara S, Miyazaki T, Ikegami T
- Journal Title
  
  Metabolites
  
  Volume: 12 Issue: 4 Pages: 331-340
- DOI
  10.3390/metabo12040331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08316, KAKENHI-PROJECT-22K06620
[Journal Article] Sex-, age-, and organ-dependent improvement of bile acid hydrophobicity by ursodeoxycholic acid treatment: A study using a mouse model with human-like bile acid composition2022
- Author(s)
  Ueda Hajime、Honda Akira、Miyazaki Teruo、Morishita Yukio、Hirayama Takeshi、Iwamoto Junichi、Nakamoto Nobuhiro、Ikegami Tadashi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 7 Pages: e0271308-e0271308
- DOI
  10.1371/journal.pone.0271308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11603, KAKENHI-PROJECT-22K06620, KAKENHI-PROJECT-23K24115
[Journal Article] Evaluation of gut dysbiosis using serum and fecal bile acid profiles.2022
- Author(s)
  Monma T, Iwamoto J, Ueda H, Tamamushi M, Kakizaki F, Konishi N, Yara S, Miyazaki T, Hirayama T, Ikegami T, Honda A
- Journal Title
  
  World J Clin Cases
  
  Volume: 10 Issue: 34 Pages: 12484-12493
- DOI
  10.12998/wjcc.v10.i34.12484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06620
[Journal Article] Relationship between the gut microbiota and bile acid composition in the ileal mucosa of Crohn’s disease2021
- Author(s)
  Shigeki Bamba, Osamu Inatomi, Atsushi Nishida,Masashi Ohno, Takayuki Imai,Kenichiro Takahashi, Yuji Naito, Junichi Iwamoto, Akira Honda, Naohiro Inohara, Akira Andoh
- Journal Title
  
  Intestinal Research
  
  Volume: ー Issue: 3 Pages: 370-380
- DOI
  10.5217/ir.2021.00054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07920, KAKENHI-PROJECT-22K06620
[Journal Article] Current states of prevention of drug-induced gastroduodenal ulcer in real clinical practice: a cross-sectional study2020
- Author(s)
  Iwamoto J, Murakami M, Monma T, Ueda H, Tamamushi M, Konishi N, Yara SI, Hirayama T, Ikegami T, Honda A, Mizokami Y
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 66 Issue: 2 Pages: 158-162
- DOI
  10.3164/jcbn.19-66
- NAID
  130007804498
- ISSN
  0912-0009, 1880-5086
- Year and Date
  2020-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08361, KAKENHI-PROJECT-18K07920
[Journal Article] Regulations of bile acid metabolism in mouse models with hydrophobic bile acid composition.2020
- Author(s)
  Honda A, Miyazaki T, Iwamoto J, Hirayama T, Morishita Y, Monma T, Ueda H, Mizuno S, Sugiyama F, Takahashi S, Ikegami T.
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 61 Issue: 1 Pages: 54-69
- DOI
  10.1194/jlr.ra119000395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07920, KAKENHI-PROJECT-18K08017, KAKENHI-PROJECT-17H04167, KAKENHI-PROJECT-16K09377
[Journal Article] Efficacy and safety of short-term therapy with indigo naturalis for ulcerative colitis: An investigator-initiated multicenter double-blind clinical trial2020
- Author(s)
  Uchiyama K, Takami S, Suzuki H, Umeki K, Mochizuki S, Kakinoki N, Iwamoto J, Hoshino Y, Omori J, Fujimori S, Yanaka A, Mizokami Y, Ohkusa T
- Journal Title
  
  PLoS One
  
  Volume: 15 Issue: 11 Pages: e0241337-e0241337
- DOI
  10.1371/journal.pone.0241337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07920
[Journal Article] The comparison of the intensity of human intestinal spirochetes between Brachyspira pilosicoli and Brachyspira aalborgi infections2019
- Author(s)
 Iwamoto J, Adachi Y, Honda A, Monma T, Matsuzaki Y
- Journal Title
 
 Journal of Clinical Biochemistry and Nutrition
 
 Volume: 64 Issue: 1 Pages: 86-90
- DOI
 10.3164/jcbn.18-68
- NAID
 130007542267
- ISSN
 0912-0009, 1880-5086
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-18K07920
[Journal Article] Simultaneous isolation of two species, Brachyspira pilosicoli and Brachyspira aalborgi, from a patient with ulcerative colitis2018
- Author(s)
 Kanazawa T, Takezawa T, Iwamoto J, Adachi Y
- Journal Title
 
 Journal of Veterinary Medical Science
 
 Volume: 80 Issue: 9 Pages: 1416-1419
- DOI
 10.1292/jvms.18-0220
- NAID
 130007482580
- ISSN
 0916-7250, 1347-7439
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-18K07920
[Journal Article] Detection of Gut Dysbiosis due to Reduced Clostridium Subcluster XIVa Using the Fecal or Serum Bile Acid Profile.2018
- Author(s)
  Murakami M, Iwamoto J, Honda A, Tsuji T, Tamamushi M, Ueda H, Monma T, Konishi N, Yara S, Hirayama T, Miyazaki T, Saito Y, Ikegami T, Matsuzaki Y.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 24 Issue: 5 Pages: 1035-1044
- DOI
  10.1093/ibd/izy022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09377, KAKENHI-PROJECT-15K00849, KAKENHI-PROJECT-18K07920, KAKENHI-PROJECT-18K08017
[Journal Article] Simultaneous quantification of salivary hydroxybutyrates as possible markers of amino acid and fatty acid catabolic pathways by LC-ESI-MS/MS2015
- Author(s)
  Miyazaki T, Honda A, Ikegami T, Iwamoto J, Monma T, Hirayama T, Saito Y, Yamashita K, Matsuzaki Y. . . .
- Journal Title
  
  Springerplus
  
  Volume: 4 Issue: 1 Pages: 494-494
- DOI
  10.1186/s40064-015-1304-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K00849, KAKENHI-PROJECT-25460042, KAKENHI-PROJECT-25461013, KAKENHI-PROJECT-25750334
[Journal Article] Serum carnitine as an independent biomarker of malnutrition in patients with impaired oral intake2014
- Author(s)
  Iwamoto J, Honda A, Miyamoto Y, Miyazaki T, Murakami M, Saito Y, Ikegami T, Miyamoto J, Matsuzaki Y
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 55 Issue: 3 Pages: 221-227
- DOI
  10.3164/jcbn.14-77
- NAID
  130004694549
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24614016
[Journal Article] Bile acid malabsorption deactivates pregnane X receptor in patients with Crohn's disease2013
- Author(s)
  Iwamoto J, Saito Y, Honda A, et al
- Journal Title
  
  Inflammatory bowel diseases
  
  Volume: 19 Issue: 6 Pages: 1278-1284
- DOI
  10.1097/mib.0b013e318281f423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590747, KAKENHI-PROJECT-23590051, KAKENHI-PROJECT-24614016, KAKENHI-PROJECT-25461013
[Presentation] 腸溶性アスピリンによる小腸粘膜傷害の機序2023
- Author(s)
  柿崎文郎,宮崎照雄, 上田元, 玉虫惇, 小西直樹, 岩本淳一, 本多彰, 池上正
- Organizer
  JDDW2023
- Data Source
  KAKENHI-PROJECT-22K06620
[Presentation] 西欧食投与によるNASH/HCCモデルマウスの作成（その１）：胆汁酸組成の違いによる病態進展への影響2022
- Author(s)
  上田　元, 宮崎照雄, 本多　彰, 岩本淳一, 池上　正
- Organizer
  第43回胆汁酸研究会
- Data Source
  KAKENHI-PROJECT-23K24115
[Presentation] 腸内環境と腎臓病治療薬　腸内細菌叢と胆汁酸代謝の関連性2020
- Author(s)
  岩本淳一
- Organizer
  第51日本消化吸収学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07920
[Presentation] 胆汁酸研究の新たな臨床展開:自己免疫性肝疾患からウイルス肝炎、生活習慣病まで　血清胆汁酸分析を用いたdysbiosisの診断と消化器疾患診療への応用2019
- Author(s)
  村上昌, 門馬匡邦, 岩本淳一
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-18K07920
[Presentation] ヒト型胆汁酸マウスにおける胆汁酸代謝2019
- Author(s)
  本多　彰，宮崎照雄，岩本淳一，平山　剛，池上　正
- Organizer
  第41回胆汁酸研究会
- Data Source
  KAKENHI-PROJECT-17H04167
[Presentation] ヒト型胆汁酸マウスにおける胆汁酸代謝2019
- Author(s)
  本多　彰、宮崎照雄、岩本淳一、平山　剛、池上　正
- Organizer
  第41回胆汁酸研究会
- Data Source
  KAKENHI-PROJECT-18K07920
[Presentation] 血中胆汁酸分析による腸管内Clostridium subcluster XIVa比率の簡易評価2018
- Author(s)
  村上　昌,岩本淳一,本多彰
- Organizer
  第49回日本消化吸収総会
- Data Source
  KAKENHI-PROJECT-18K07920
[Presentation] Detection of gut dysbiosis due to reduced Clostridium subcluster XIVa based on the serum bile acid profile.2017
- Author(s)
  Murakami M, Iwamoto J, Miyazaki T, Monma T, Shoichiro Y, Ikegami T, Matsuzaki Y, Honda A.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00849
[Presentation] 脂肪性肝炎進展過程における酸化ステロールの質的変化2016
- Author(s)
  屋良昭一郎, 池上　正，本多　彰，岩本淳一，宮﨑照雄，松﨑靖司.
- Organizer
  第20回日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K00849
[Presentation] Dysregulation of hepatic 27-hydroxycholesterol in steatohepatitis model mice with hyperglycemia2016
- Author(s)
  Yara S, Ikegami T, Honda A, Miyazaki T, Monma T, Murakami M, Konishi N, Iwamoto J, Saito Y, Matsuzaki Y
- Organizer
  25th Conference of the APASL
- Place of Presentation
  Tokyo
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00849
[Presentation] 脂質，胆汁酸代謝からみたクローン病における脂肪肝合併メカニズムについての検討2014
- Author(s)
  岩本淳一
- Organizer
  日本消化器病学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24614016
[Presentation] 胆汁酸研究の最近の進歩クローン病における核内レセプターPregnane X receptorの活性低下と胆汁酸吸収障害の影響2013
- Author(s)
  岩本淳一、本多彰、宮崎照雄
- Organizer
  肝臓学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24614016
[Presentation] 炎症性腸疾患における血清ステロールの検討2012
- Author(s)
  岩本淳一、本多彰、松崎靖司
- Organizer
  日本消化器病学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24614016

1. MIYAZAKI Teruo (60532687)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
2. HONDA Akira (10468639)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
3. 池上正 (40439740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 平山剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iwamoto Junichi 岩本 淳一

IWAMOTO JUNICHI 岩本 淳一

Research Projects

Research Products

Co-Researchers

低用量アスピリンによる小腸粘膜障害発症メカニズムの解明とリスク予測法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

胆汁酸ヒト化マウスを用いたNAFL/NASH/HCC進展メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Serum bile acid analysis of patients with Clostridium difficile -associated diarrheaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Production and phenotype analysis of mouse models with humanized bile acid composition

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Serum metabolomics analysis of patients with fatty liver due to undernutritionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new biomarkers for small intestinal malabsorptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Background factors of idiopathic peptic ulcers and optimal treatment methods: a multicenter retrospective Japanese study2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] 西欧食による腸内細菌叢と胆汁酸代謝への影響2023

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of the risk of Clostridium difficile infection using a serum bile acid profile2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sex-, age-, and organ-dependent improvement of bile acid hydrophobicity by ursodeoxycholic acid treatment: A study using a mouse model with human-like bile acid composition2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of gut dysbiosis using serum and fecal bile acid profiles.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relationship between the gut microbiota and bile acid composition in the ileal mucosa of Crohn’s disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current states of prevention of drug-induced gastroduodenal ulcer in real clinical practice: a cross-sectional study2020

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Iwamoto Junichi 岩本淳一

IWAMOTO JUNICHI 岩本淳一

[Presentation] 西欧食投与によるNASH/HCCモデルマウスの作成（その１）：胆汁酸組成の違いによる病態進展への影響2022

[Presentation] 腸内環境と腎臓病治療薬　腸内細菌叢と胆汁酸代謝の関連性2020

[Presentation] 胆汁酸研究の新たな臨床展開:自己免疫性肝疾患からウイルス肝炎、生活習慣病まで　血清胆汁酸分析を用いたdysbiosisの診断と消化器疾患診療への応用2019