Hira Tohru 比良徹

… Alternative Names

HIRA Tohru 比良徹

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Researcher Number	10396301
Other IDs	https://orcid.org/0000-0002-0354-1617
Affiliation (Current)	2025: 北海道大学, 農学研究院, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 北海道大学, 農学研究院, 准教授 2016 – 2019: 北海道大学, 農学研究院, 講師 2012 – 2016: 北海道大学, (連合)農学研究科(研究院), 講師 2013 – 2014: 北海道大学, 大学院農学研究院, 講師 2011 – 2012: 北海道大学, (連合)農学研究科(研究院), 助教 … More 2007 – 2010: 北海道大学, 大学院・農学研究院, 助教 2006: 北海道大学, 大学院農学研究院, 助手 2005: 北海道大学, 大学院・農学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Food science / Basic Section 38050:Food sciences-related / Medium-sized Section 38:Agricultural chemistry and related fields Except Principal Investigator Food science / Medium-sized Section 38:Agricultural chemistry and related fields
Keywords	Principal Investigator 食事誘導性肥満 / GLP-1 / 消化管ホルモン / 消化管内分泌系 / 食品たんぱく質 / 受容体 / 食品ペプチド / コレシストキニン / 消化管内分泌細胞 / ペプチド … More / DPP-4 / 耐糖能異常 / 消化管内分泌 / 糖尿病 / 肥満誘導食 / 栄養素感受性 / 食事負荷試験 / 食後血糖 / コレシストキン / 食品タンパク質 / 栄養素受容体 / Calcium-sensing receptor / カルシウム感知受容体 / 満腹感 … More Except Principal Investigator 消化管ホルモン / GLP-1 / 消化管内分泌系 / 難消化性糖質 / 消化管内分泌細胞 / 食品ペプチド / コレシストキニン / 腸間膜静脈 / 栄養素吸収 / 回腸部腸間膜静脈カテーテル / 門脈カテーテル / 炭水化物 / 消化吸収 / 回腸部腸間膜静脈 / 門脈 / 食後消化管ホルモン分泌 / 食後栄養素吸収 / 腸上皮バリア機能 / フラボノイド / 腸管バリア / ペプチドYY / ポリフェノール / グルカゴン様ペプチド１ / ケルセチン / 消化管バリア / イソマルトメガロ糖 / 栄養センサー / GIP / 難消化性デキストリン / アルロース / 食事組成 / 腸間膜リンパ節 / 腸管リンパ / glucagon-like peptide / 慢性炎症 / 脂肪組織 / メタボリック症候群 / interleukin-6 / chronic inflammation / 低消化性糖質 / インクレチン / 難消化性ペプチド / 消化抵抗性糖質 / Glucagon-like peptide-1 / 血糖値 Less

GLP-1分泌促進と分解抑制の両作用を併せ持つペプチドの創生Principal Investigator
- Principal Investigator
  
  比良徹
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Hokkaido University
Protective mechanisms of enteroendocrine systems against diet-induced obesity and glucose intolerancePrincipal Investigator
- Principal Investigator
  
  比良徹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Hokkaido University
Mechanisms underlying enhanced GLP-1 response in diet-induced obesityPrincipal Investigator
- Principal Investigator
  
  Hira Tohru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Hokkaido University
Study on postprandial nutrient and gut hormone responses in different intestinal regions
- Principal Investigator
  
  Hara Hiroshi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Fuji Women's University
  Hokkaido University
Study on physiological effects of isomalto-megalo-saccharides
- Principal Investigator
  
  Hara Hiroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Food science
- Research Institution
  Fuji Women's University
  Hokkaido University
Regulation of gut nutrient sensing mechanisms in response to dietary interventionPrincipal Investigator
- Principal Investigator
  
  Hira Tohru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Study on sensing mechanism of low-digestible saccharides in nutrient-sensing enteroendocrine cells
- Principal Investigator
  
  Hara Hiroshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Study on enteroendocrine, nervous and reproductive systems related to diet for preventing metabolic diseases.
- Principal Investigator
  
  Hara Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Role of GLP-1 during the development of diet-induced obesity and glucose impairmentPrincipal Investigator
- Principal Investigator
  
  HIRA Tohru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Elucidation of mechanisms to avoid chronic inflammation via enteroendocrine system: relationships between immune cells and adipocytes
- Principal Investigator
  
  ISHIZUKA Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Searching for dietary protein/peptide sensing receptors in enteroendocrine cellsPrincipal Investigator
- Principal Investigator
  
  HIRA Tohru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Enhancement of dietary peptide-induced GLP-1 secretion by indigestible saccharides
- Principal Investigator
  
  HARA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Role of CaSR as dietary peptide sensor and search for dietary protein receptor in the gutPrincipal Investigator
- Principal Investigator
  
  HIRA Tohru
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
Development of anti-obese dietary peptides which functions via gut hormone secretion
- Principal Investigator
  
  HARA Hiroshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University
食品タンパク質中の満腹感促進ペプチドの探索と消化管内分泌細胞におけるその受容機構Principal Investigator
- Principal Investigator
  
  比良徹
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Hokkaido University

[Book] 生物化学実験法50 腸管細胞機能実験法2005
- Author(s)
  上野川修一, 清水誠, 八村敏志, 戸塚護編著, 比良徹共著
- Total Pages
  247
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-17780097
[Journal Article] "食品タンパク質・ペプチドによるGLP-1分泌促進とそれによる血糖上昇抑制、体温上昇作用 "2024
- Author(s)
  比良　徹
- Journal Title
  
  日本栄養・食糧学会誌
  
  Volume: 77 Pages: 13-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] Effect of Single Oral Coingestion of GABA and Malic Acid on Postprandial GLP‐1, Glucose, and Insulin Responses in Healthy Volunteers: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study2024
- Author(s)
  Noguchi Hiroki、Ikenaga Takeshi、Ueno Shota、Kohashi Chieko、Matsumura Yasuhiro、Kakumoto Yusuke、Kohda Noriyuki、Hara Hiroshi、Hira Tohru
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 68 Issue: 7
- DOI
  10.1002/mnfr.202300610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] Synergistic enhancement of glucagon-like peptide-1 release by γ-aminobutyric acid and L-phenylalanine in enteroendocrine cells searching active ingredients in a water extract of corn zein protein2023
- Author(s)
  Noguchi Hiroki、Kohda Noriyuki、Hara Hiroshi、Hira Tohru
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 87 Issue: 12 Pages: 1505-1513
- DOI
  10.1093/bbb/zbad124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] ルミナコイドによる消化管ホルモン分泌促進作用に関する研究2023
- Author(s)
  比良　徹
- Journal Title
  
  ルミナコイド研究
  
  Volume: 27 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] Glucagon-Like Peptide-1 Is Involved in the Thermic Effects of Dietary Proteins in Male Rodents2023
- Author(s)
  Ochiai Keita、Muto Asuka、Seok Bong Soo、Doi Yuta、Iwasaki Yusaku、Okamatsu-Ogura Yuko、Drucker Daniel J、Hira Tohru
- Journal Title
  
  Endocrinology
  
  Volume: 164 Issue: 6
- DOI
  10.1210/endocr/bqad068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] Trp-Tyr is a dipeptide structure that potently stimulates GLP-1 secretion in a murine enteroendocrine cell model, identified by comprehensive analysis2023
- Author(s)
  Taguchi Hayate、Murai Kana、Hira Tohru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 661 Pages: 28-33
- DOI
  10.1016/j.bbrc.2023.04.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] 2‐Arachidonoyl glycerol suppresses gastric emptying via the cannabinoid receptor 1‐cholecystokinin signaling pathway in mice2022
- Author(s)
  Ochiai Keita、Hirooka Rina、Sakaino Masayoshi、Takeuchi Shigeo、Hira Tohru
- Journal Title
  
  Lipids
  
  Volume: 57 Issue: 3 Pages: 173-181
- DOI
  10.1002/lipd.12341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] Direct visualization of GLP‐1 secretion by fluorescent fusion proteins2022
- Author(s)
  Tsuzuki Atsushi、Fujioka Yoichiro、Yoshida Aiko、Kashiwagi Sayaka、Amano Maho、Hira Tohru、Nakamura Akinobu、Miyoshi Hideaki、Atsumi Tatsuya、Ohba Yusuke
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 7 Pages: 1134-1139
- DOI
  10.1111/jdi.13800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16211, KAKENHI-PUBLICLY-21H00413, KAKENHI-PLANNED-20H05872, KAKENHI-PROJECT-21K19347, KAKENHI-PROJECT-23K23544
[Journal Article] Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin2022
- Author(s)
  Harada Naoki、Okuyama Mai、Teraoka Yoshiaki、Arahori Yumi、Shinmori Yoh、Horiuchi Hiroko、Luis Paula B.、Joseph Akil I.、Kitakaze Tomoya、Matsumura Shigenobu、Hira Tohru、Yamamoto Norio、Iuni Takashi、Goshima Naoki、Schneider Claus、Inui Hiroshi、Yamaji Ryoichi
- Journal Title
  
  npj Science of Food
  
  Volume: 6 Issue: 1 Pages: 4-4
- DOI
  10.1038/s41538-021-00119-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05866, KAKENHI-PROJECT-19H02913, KAKENHI-PROJECT-21K14803, KAKENHI-PROJECT-23K23544
[Journal Article] 難消化性デキストリン，フルクトオリゴ糖長期摂取ラットにおける，食品ペプチド誘導性GLP-1分泌応答2022
- Author(s)
  比良徹, 原博
- Journal Title
  
  ルミナコイド研究
  
  Volume: 26 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23544
[Journal Article] Blood Sampling From Rat Ileal Mesenteric Vein Revealed a Major Role of Dietary Protein in Meal-Induced GLP-1 Response2021
- Author(s)
  Hira Tohru、Sekishita Madoka、Hara Hiroshi
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 12 Pages: 1-8
- DOI
  10.3389/fendo.2021.689685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05860
[Journal Article] Improvement of Glucose Tolerance by Food Factors Having Glucagon-Like Peptide-1 Releasing Activity2021
- Author(s)
  Hira Tohru、Trakooncharoenvit Aphichat、Taguchi Hayate、Hara Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 12 Pages: 6623-6623
- DOI
  10.3390/ijms22126623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05860
[Journal Article] Acute Oral Calcium Suppresses Food Intake Through Enhanced Peptide-YY Secretion Mediated by the Calcium-Sensing Receptor in Rats2021
- Author(s)
  Igarashi Akiho、Ogasawara Shono、Takagi Ryo、Okada Kazufumi、Ito Yoichi M、Hara Hiroshi、Hira Tohru
- Journal Title
  
  The Journal of Nutrition
  
  Volume: 151 Issue: 5 Pages: 1320-1328
- DOI
  10.1093/jn/nxab013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05860
[Journal Article] Expression of serotonin receptor HTR4 in glucagon-like peptide-1-positive enteroendocrine cells of the murine intestine2020
- Author(s)
  Okumura Motoshi、Hamada Akihiro、Ohsaka Fumina、Tsuruta Takeshi、Hira Tohru、Sonoyama Kei
- Journal Title
  
  Pfl?gers Archiv - European Journal of Physiology
  
  Volume: 472 Issue: 10 Pages: 1521-1532
- DOI
  10.1007/s00424-020-02453-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05860, KAKENHI-PROJECT-20H02927, KAKENHI-PROJECT-19J10216, KAKENHI-PROJECT-20K11580
[Journal Article] What Is GLP-1 Really Doing in Obesity?2020
- Author(s)
  Hira Tohru、Pinyo Jukkrapong、Hara Hiroshi
- Journal Title
  
  Trends in Endocrinology & Metabolism
  
  Volume: 31 Issue: 2 Pages: 71-80
- DOI
  10.1016/j.tem.2019.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05860
[Journal Article] Diet-induced obesity enhances postprandial glucagon-like peptide-1 secretion in Wistar rats, but not in diabetic Goto-Kakizaki rats2020
- Author(s)
  Pinyo Jukkrapong、Hara Hiroshi、Hira Tohru
- Journal Title
  
  British Journal of Nutrition
  
  Volume: - Issue: 4 Pages: 1-13
- DOI
  10.1017/s000711452000433x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05860
[Journal Article] Glucagon-like peptide-1 response to whey protein is less diminished by dipeptidyl peptidase-4 in comparison with responses to dextrin, a lipid and casein in rats2020
- Author(s)
  Shimizu Yuki、Hara Hiroshi、Hira Tohru
- Journal Title
  
  British Journal of Nutrition
  
  Volume: 125 Issue: 4 Pages: 398-407
- DOI
  10.1017/s0007114520002834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05860
[Journal Article] Water-soluble dietary fibers enhance bioavailability of quercetin and a fiber derived from soybean is most effective after long-term feeding in rats.2019
- Author(s)
  Trakooncharoenvit A, Tanaka S, Mizuta E, Hira T, Hara H.
- Journal Title
  
  Eur J Nutr.
  
  Volume: - Issue: 4 Pages: 1389-1398
- DOI
  10.1007/s00394-019-01992-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01473
[Journal Article] Reply to the Letter: Increased bioavailability of plasma polyphenols via the intestinal fermentation of soybean fibers: a role for gut microbiome?2019
- Author(s)
  Trakooncharoenvit A, Tanaka S, Mizuta E, Hira T, Hara H.
- Journal Title
  
  Eur J Nutr.
  
  Volume: - Issue: 6 Pages: 2563-2563
- DOI
  10.1007/s00394-019-02030-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01473
[Journal Article] Enhanced postprandial glucagon-like peptide-1 secretion during obesity development has a protective role against glucose intolerance induction in rats2019
- Author(s)
  Pinyo Jukkrapong、Hira Tohru、Hara Hiroshi
- Journal Title
  
  British Journal of Nutrition
  
  Volume: 122 Issue: 04 Pages: 411-422
- DOI
  10.1017/s0007114519001223
- NAID
  120006882089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05860
[Journal Article] Continuous feeding of a combined high-fat and high-sucrose diet, rather than an individual high-fat or high-sucrose diet, rapidly enhances the glucagon-like peptide-1 secretory response to meal ingestion in diet-induced obese rats2019
- Author(s)
  Pinyo Jukkrapong、Hira Tohru、Hara Hiroshi
- Journal Title
  
  Nutrition
  
  Volume: 62 Pages: 122-130
- DOI
  10.1016/j.nut.2019.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07725
[Journal Article] Secretion of GLP-1 but not GIP is potently stimulated by luminal d -Allulose ( d -Psicose) in rats2018
- Author(s)
  Hayakawa Masaki、Hira Tohru、Nakamura Masako、Iida Tetsuo、Kishimoto Yuka、Hara Hiroshi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496 Issue: 3 Pages: 898-903
- DOI
  10.1016/j.bbrc.2018.01.128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14918
[Journal Article] Impact of difructose anhydride III, raffinose, and fructooligosaccharides on energy intake, gut hormones, and cecal fermentation in rats fed a high-fat and high-sucrose diet.2017
- Author(s)
  Hira T, Yanagihara K, Koga T, Takahashi K, Nagura T, Uchino H, Hara H.
- Journal Title
  
  Biosci Biotechnol Biochem.
  
  Volume: 81 Issue: 11 Pages: 2186-2194
- DOI
  10.1080/09168451.2017.1373591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07725
[Journal Article] Resistant maltodextrin or fructooligosaccharides promotes GLP-1 production in male rats fed a high-fat and high-sucrose diet, and partially reduces energy intake and adiposity2017
- Author(s)
  Tohru Hira, Ryoya Suto, Yuka Kishimoto, Sumiko Kanahori, Hiroshi Hara
- Journal Title
  
  EUROPEAN JOURNAL OF NUTRITION
  
  Volume: - Issue: 3 Pages: 965-979
- DOI
  10.1007/s00394-017-1381-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26252016
[Journal Article] Resistant maltodextrin promotes fasting GLP-1 secretion and production together with glucose tolerance in rats2015
- Author(s)
  Tohru Hira, Asuka Ikee, Yuka Kishimoto, Sumiko Kanahori, Hiroshi Hara
- Journal Title
  
  BRITISH JOURNAL OF NUTRITION
  
  Volume: 114 Issue: 1 Pages: 34-42
- DOI
  10.1017/s0007114514004322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450159
[Journal Article] Postprandial GLP-1 secretion is increased during the progression of glucose intolerance and obesity in high-fat/high-sucrose diet fed rats.2015
- Author(s)
  Nakajima S, Hira T, Hara H.
- Journal Title
  
  Br J Nutr.
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25450159
[Journal Article] A nondigestible saccharide, fructooligosaccharide, increases the promotive effect of a flavonoid, alpha-glucosyl-isoquercitrin, on glucagon-like peptide 1 (GLP-1) secretion in rat intestine and enteroendocrine cells2014
- Author(s)
  Phuwamongkolwiwat P, Hira T, Hara H.
- Journal Title
  
  Molecular Nutrition and Food Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] Unsaturated aldehydes induce CCK secretion via TRPA1 in STC-1 cells2014
- Author(s)
  Nakajima S, Hira T, Yahagi A, Nishiyama C, Yamashita T, Imagi J, Hara H
- Journal Title
  
  Mol Nutr Food Res
  
  Volume: 58(5) Issue: 5 Pages: 1042-51
- DOI
  10.1002/mnfr.201300412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070, KAKENHI-PROJECT-23780124
[Journal Article] A nondigestible saccharide, fructooligosaccharide, increases the promotive effect of a flavonoid,α-glucosyl-isoquercitrin, on glucagon-like peptide 1 (GLP-1) secretion in rat intestine and enteroendocrine cells2014
- Author(s)
  Phuwamongkolwiwat P, Hira T, Hara H
- Journal Title
  
  Mol Nutr Food Res
  
  Volume: (in press) Issue: 7 Pages: 1581-1584
- DOI
  10.1002/mnfr.201300871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] Fructooligosaccharide augments benefits of quercetin-3-O-β-glucoside on insulin sensitivity and plasma total cholesterol with promotion of flavonoid absorption in sucrose-fed rats2014
- Author(s)
  Phuwamongkolwiwat P, Suzuki T, Hira T, Hara H
- Journal Title
  
  Eur J Nutr. Mar
  
  Volume: 53(2) Issue: 2 Pages: 457-68
- DOI
  10.1007/s00394-013-0546-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] Oral administration of corn zein hydrolysate stimulates GLP-1 and GIP secretion and improves glucose tolerance in male normal rats and Goto-Kakizaki rats2013
- Author(s)
  Higuchi N, Hira T, Yamada N, Hara H
- Journal Title
  
  Endocrinology
  
  Volume: 154(9) Pages: 3089-98
- Data Source
  KAKENHI-PROJECT-23780124
[Journal Article] Oral administration of corn Zein hydrolysate stimulates GLP-1 and GIP secretion and improves glucose tolerance in male normal rats and Goto-Kakizaki rats2013
- Author(s)
  Higuchi N, Hira T, Yamada N, Hara H
- Journal Title
  
  Endocrinology
  
  Volume: 154(9) Issue: 9 Pages: 3089-98
- DOI
  10.1210/en.2012-2275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070, KAKENHI-PROJECT-23780124
[Journal Article] Suppressive effect on food intake of a potato extract (Potein®) involving cholecystokinin release in rats2012
- Author(s)
  Chen W, Hira T, Nakajima S, Tomozawa H, Tsubata M, Yamaguchi K, Hara H
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 76(6) Pages: 1104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780124
[Journal Article] 腸管での栄養素認識と消化ホルモン分泌＜平成24年度日本栄養・食糧学会奨励賞受賞＞2012
- Author(s)
  比良　徹
- Journal Title
  
  日本栄養・食糧学会誌
  
  Volume: 65 Pages: 215-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780124
[Journal Article] Calium-sensing receptor mediates dietary peptide-induced CCK secretion in enteroendocrine STC-1 cells.2012
- Author(s)
  Nakajima S
- Journal Title
  
  Mol. Nutr. Food. Res.
  
  Volume: 56 Issue: 5 Pages: 753-760
- DOI
  10.1002/mnfr.201100666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07124, KAKENHI-PROJECT-23780124
[Journal Article] Suppressive Effect on Food Intake of a Potato Extract (Potein) Involving Cholecystokinin Release in Rats2012
- Author(s)
  Chen, Wenya; HIRA, Tohru; NAKAJIMA, Shingo; TOMOZAWA, Hiroshi; TSUBATA, Masahito; YAMAGUCHI, Kazuya; HARA, Hiroshi
- Journal Title
  
  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
  
  Volume: 76 Pages: 1104-1109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780124
[Journal Article] 腸管での栄養素認識と消化管ホルモン分泌に関する研究(平成24年度日本栄養・食糧学会奨励賞受賞)2012
- Author(s)
  比良徹
- Journal Title
  
  日本栄養・食糧学会誌
  
  Volume: 65(5) Pages: 215-220
- NAID
  130002129275
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] Soybean .BETA.-Conglycinin Bromelain Hydrolysate Stimulates Cholecystokinin Secretion by Enteroendocrine STC-1 Cells to Suppress the Appetite of Rats under Meal-Feeding Conditions2011
- Author(s)
  Bin Sufian, Md. Kaosar Niaz; Hira, Tohru; Nakamori, Toshihiro; Furuta, Hitoshi; Asano, Kozo; Hara, Hiroshi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 75 Issue: 5 Pages: 848-853
- DOI
  10.1271/bbb.100765
- NAID
  10028272318
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] Potato extract (Potein) suppresses food intake in rats through inhibition of luminal trypsin activity and direct stimulation of cholecystokinin secretion from enteroendocrine cells.2011
- Author(s)
  Nakajima S
- Journal Title
  
  J Agric Food Chem.
  
  Volume: 59 Issue: 17 Pages: 9491-9496
- DOI
  10.1021/jf200988f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07124, KAKENHI-PROJECT-22380070
[Journal Article] Soybeanβ-Conglycinin Bromelain Hydrolysate Stimulates Cholecystokinin Secretion by Enteroendocrine STC-1 Cells to Suppress the Appetite of Rats under Meal-Feeding Conditions2011
- Author(s)
  Sufian KN, Hira T, Nakamori T, Furuta H, Asano K, Hara H
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry
  
  Volume: 75(5) Pages: 845-53
- NAID
  10028272318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] 消化管ホルモンを介して食欲をコントロールする食品由来ペプチド2011
- Author(s)
  原博、中島進吾、比良徹
- Journal Title
  
  臨床化学(特集)(日本臨床化学会)
  
  Volume: 40(2) Pages: 119-12
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] インクレチン分泌を刺激する食品ペプチド、アミノ酸?消化管内分泌細胞による栄養素認識、Nutirient sensingの解明と応用に期待2011
- Author(s)
  比良徹
- Journal Title
  
  化学と生物、今日の話題(日本農芸化学会)
  
  Volume: 48(No. 1) Pages: 11-13
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] Acute effect of soybean beta-conglycinin hydrolysate ingestion on appetite sensations in healthy humans2011
- Author(s)
  Hira T, Mori N, Nakamori T, Furuta H, Asano K, Chiba H, Hara H
- Journal Title
  
  Appetite
  
  Volume: 57(3) Issue: 3 Pages: 765-8
- DOI
  10.1016/j.appet.2011.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] GLP-1 Secretion in Response to Oral and Luminal Palatinose (Isomaltulose) in Rats2011
- Author(s)
  Hira T, Muramatsu M, Okuno M, Hara H
- Journal Title
  
  J Nutr Sci Vitaminol
  
  Volume: 57(1) Pages: 30-35
- NAID
  10028106023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] GLP-1 secretion in response to oral and luminal palatinose (isomaltulose) in rats2011
- Author(s)
  Hira T, Muramatsu M, Okuno M, Hara H
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 57(1) Pages: 30-25
- NAID
  10028106023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] インクレチン分泌を刺激する食品ペプチド、アミノ酸～消化管内分泌細胞による栄養素認識、Nutirient sensingの解明と応用に期待2011
- Author(s)
  比良徹
- Journal Title
  
  化学と生物(今日の話題)
  
  Volume: 48(1) Pages: 11-13
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] ラットにおけるトウモロコシZein加水分解物によるGLP-1分泌を介した血糖上昇抑制2010
- Author(s)
  比良徹、持田泰佑、原博
- Journal Title
  
  アミノ酸研究
  
  Volume: 4(2) Pages: 163-66
- Data Source
  KAKENHI-PROJECT-22380070
[Journal Article] Soybean <beta>51-63 peptide stimulates cholecystokinin secretion via a calcium-sensing receptor in enteroendocrine STC-1 cells2010
- Author(s)
  Shingo Nakajima、Tohru Hira、Yuzuru Eto、Kozo Asano、Hiroshi Hara
- Journal Title
  
  Regulatory Peptides Vol. 159 (1-3)
  
  Pages: 148-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Soybean <beta> 51-63 peptide stimulates cholecystokinin secretion via a calcium-sensing receptor in enteroendocrine STC-1 cells2010
- Author(s)
  Nakajima S, Hira T, Eto Y, Asano K.Hara H
- Journal Title
  
  Regulatory Peptides 159(1-3)
  
  Pages: 148-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21780118
[Journal Article] The corn protein, Zein, hydrolysate administered into the ileum attenuates hyperglycemia via its dual action on GLP-1 secretion and DPP-IV activity in rats2010
- Author(s)
  Taisuke Mochida、Tohru Hira、Hiroshi Hara
- Journal Title
  
  Endocrinology Vol.151(7)
  
  Pages: 3095-13104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] The corn protein, Zein, hydrolysate administered into the ileum attenuates hyperglycemia via its dual action on GLP-1 secretion and DPP-IV activity in rats2010
- Author(s)
  Mochida T, Hira T, Hara H
- Journal Title
  
  Endocrinology
  
  Volume: 151(7) Pages: 3095-13104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Soybean <beta>51-63 peptide stimulates cholecystokinin secretion via a calcium-sensing receptor in enteroendocrine STC-1 cells2010
- Author(s)
  Shingo Nakajima, Tohru Hira, Yuzuru Eto, Kozo Asano, Hiroshi Hara
- Journal Title
  
  Regulatory Peptides Vol.159(1-3)
  
  Pages: 148-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21780118
[Journal Article] ペプチド栄養学の新展開2009
- Author(s)
  原博、比良徹
- Journal Title
  
  フードリサーチ Vol.647
  
  Pages: 62-66
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Cholecystokinin secretion induced by beta-conglycinin peptone depends on Galphaq-mediated pathways in enteroendocrine cells2009
- Author(s)
  Tohru Hira、Toshihiro Maekawa、Kozo Asano、Hiroshi Hara
- Journal Title
  
  European Journal of Nutrition Vol. 48(2)
  
  Pages: 124-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Cholecystokinin secretion induced by beta-conglycinin peptone depends on Galphaq-mediated pathways in enteroendocrine cells2009
- Author(s)
  Hira T, Maekawa T, Asano K, & Hara H
- Journal Title
  
  European Journal of Nutrition 48(2)
  
  Pages: 124-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Soybean <beta>51-63 peptide stimulates cholecystokinin secretion via a calcium-sensing receptor in enteroendocrine STC-1 cells2009
- Author(s)
  Nakajima S, Hira T, Eto Y, Asano K, Hara H
- Journal Title
  
  Regulatory Peptides
  
  Volume: 159(1-3) Pages: 148-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] ペプチド栄養学の新展開2009
- Author(s)
  原博、比良徹
- Journal Title
  
  フードリサーチ
  
  Volume: 647 Pages: 62-66
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] GLP-1 secretion is enhanced directly in the ileum, but indirectly in the duodenum by a newly identified potent stimulator, zein hydrolysate in rats2009
- Author(s)
  Hira T, Mochida T, Miyashita K, Hara H
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology
  
  Volume: 647(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] GLP-1 secretion is enhanced directly in the ileum, but indirectly in the duodenum by a newly identified potent stimulator, zein hydrolysate in rats2009
- Author(s)
  Tohru Hira、Taisuke Mochida、Kyoko Miyashita、Hiroshi Hara
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology Vol. 647(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Calcium-sensing receptor mediates phenylalanine-induced cholecystokinin secretion in enteroendocrine STC-1 cells2008
- Author(s)
  Hira T, Nakajima S, Eto Y & Hara H
- Journal Title
  
  FEBS Journal 275(18)
  
  Pages: 4620-4626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Calcium-sensing receptor mediates phenylalanine-induced cholecystokinin secretion in enteroendocrine STC-1 cells2008
- Author(s)
  Tohru Hira、Shingo Nakajima、Yuzuru Eto、Hiroshi Hara
- Journal Title
  
  FEBS Journal Vol. 275(18)
  
  Pages: 4620-4626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Dolicholin', a phaseolin-like protein in country beans (Dolichos lablab), potently stimulate cholecystokinin secretion from enteroendocrine STC-1 cells2007
- Author(s)
  Md Kaosar Niaz Bin Sufian、Tohru Hira、 Kozo Asano、Hiroshi Hara
- Journal Title
  
  Journal of Agricultural and Food Chemistry Vol.55(22)
  
  Pages: 8980-8986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Sucrose fatty acid ester suppresses pancreatic secretion accompanied by peptide YY release in pancreatico-biliary diverted rats.2007
- Author(s)
  Hira T, Takahashi K, Hara H
- Journal Title
  
  Experimental Physiology (印刷中)
- Data Source
  KAKENHI-PROJECT-17780097
[Journal Article] Dolicholin', a phaseolin-like protein in country beans (Dolichos lablab), potently stimulate cholecystokinin secretion from enteroendocrine STC-1 cells2007
- Author(s)
  Sufian, M., Hira T., Asano, K., Hara, H
- Journal Title
  
  Journal of Agricultural and Food Chemistry 55(22)
  
  Pages: 8980-8986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19380071
[Journal Article] Mouse GPR40 receptor heterologously expressed in Xenopus oocytes is activated by short, medium and long chain fatty acids.2006
- Author(s)
  Stewart, G, Hira T, Higgins, A, Smith, CP, McLaughlin, JT
- Journal Title
  
  American Journal of Physiology, Cell Physiology. 290(3)
- Data Source
  KAKENHI-PROJECT-17780097
[Journal Article] Pork peptone stimulates cholecystokinin secretion from enteroendocrine cells and suppresses appetite in rats.2006
- Author(s)
  Sufian M., Hira T., Miyashita K., Nishi T., Asano K., Hara H.
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry 290 (3)
  
  Pages: 1869-1874
- NAID
  10018528008
- Data Source
  KAKENHI-PROJECT-17780097
[Patent] 血中ジペプチジルペプチダーゼ-IV阻害活性およびグルカゴン様ペプチド-1の分泌促進活性を併せ持つ組成物2010
- Inventor(s)
  比良徹、原博、浅野行蔵
- Industrial Property Rights Holder
  比良徹、原博、浅野行蔵
- Industrial Property Number
  2010-053383
- Acquisition Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-19380071
[Patent] 血中ジペプチジルペプチダーゼ-IV阻害活性およびグルカゴン様ペプチド-1の分泌促進活性を併せ持つ組成物2010
- Inventor(s)
  原博、比良徹、浅野行蔵
- Industrial Property Rights Holder
  原博、比良徹、浅野行蔵
- Industrial Property Number
  2010-053383
- Filing Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-19380071
[Patent] GLP-1分泌促進物2008
- Inventor(s)
  比良徹、原博
- Industrial Property Rights Holder
  比良徹、原博、北海道大学
- Industrial Property Number
  2008-313160
- Acquisition Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-19380071
[Patent] GLP-1分泌促進物2008
- Inventor(s)
  比良徹, 原博
- Industrial Property Rights Holder
  比良徹, 原博, 北海道大学
- Industrial Property Number
  2008-313160
- Filing Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] 食品成分による消化管ホルモン分泌の調節2023
- Author(s)
  比良　徹
- Organizer
  第111回日本栄養・食糧学会関東支部シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K23544
[Presentation] 食品タンパク質・ペプチドによる GLP-1 分泌促進とそれによる血糖上昇抑制、体温上昇作用2023
- Author(s)
  比良　徹
- Organizer
  第77回日本栄養・食糧学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23544
[Presentation] 希少糖D-アルロースによるGLP-1分泌促進機構2023
- Author(s)
  比良　徹
- Organizer
  第14回日本安定同位体・生体ガス医学応用学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23544
[Presentation] Acute and chronic administration of alpha-linolenic acid respectively potentiates nutrient-induced GLP-1 secretion in rats2022
- Author(s)
  Rino Kimura, Anri Sano, Tohru Hira
- Organizer
  22nd IUNS-ICN International Congress of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23544
[Presentation] Adaptive changes in nutrient-induced GLP-1 secretion in diet-induced obese model rats2022
- Author(s)
  Tohru Hira
- Organizer
  22nd IUNS-ICN International Congress of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23544
[Presentation] ラットにおけるえごま油長期摂食による食事刺激に対する GLP- 1分泌への影響2022
- Author(s)
  木村梨乃，佐野杏莉，比良徹
- Organizer
  第 76 回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-23K23544
[Presentation] 消化管内分泌系への作用を介する糖代謝改善ペプチド2021
- Author(s)
  比良徹
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] 食事誘導性肥満ラットにおける消化管部位別のGLP-1分泌応答と組織解析2021
- Author(s)
  佐野杏莉、比良徹
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] ラットにおけるえごま油長期摂取は、食事刺激に対するGLP-１分泌応答および持続性を高める2021
- Author(s)
  木村梨乃，佐野杏莉，比良徹
- Organizer
  令和3年度日本栄養・食糧学会　東北支部（第55回大会）・北海道支部（第51回大会）合同支部大会およびシンポジウム
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] 食事誘導性肥満ラットにおけるGLP-1分泌応答の増強には回腸部が寄与する2020
- Author(s)
  佐野杏莉、比良徹
- Organizer
  日本農芸化学会　2020年度大会
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] ラットにおける大豆タンパク質経口投与時のGLP-1分泌応答と血中DPP-4活性の低下2020
- Author(s)
  村井佳奈、比良徹
- Organizer
  日本アミノ酸学会第14回学術大会
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] ラットにおける伸展刺激負荷による GLP-1 分泌応答の解析2020
- Author(s)
  木村夏織，比良徹
- Organizer
  2020年度日本農芸化学会北海道支部／第50回日本栄養・食糧学会北海道支部　合同学術講演会　優秀発表賞／若手奨励賞
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] ラット門脈ならびに回腸部腸間膜静脈における食後のグルコース濃度と消化管ホルモン濃度の変動2020
- Author(s)
  蒲地美南、原博、比良徹
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-18K19158
[Presentation] Postprandial GLP-1 response was enhanced in non-diabetic rats, but not in diabetic rats during obesity development2019
- Author(s)
  Jukkrapong PINYO, Tohru HIRA, Hiroshi HARA
- Organizer
  International Diabetes Federation 2019 (IDF 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] 食事誘導性肥満ラットにおけるGLP-1の分泌応答と小腸上部および下部での違い2019
- Author(s)
  佐野杏莉、比良徹
- Organizer
  日本農芸化学会北海道支部第２回講演会
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] bined feeding of α-glycosyl-isoquercitrin and soluble soybean fiber prevents glucose intolerance in rats2019
- Author(s)
  Aphichat Trakooncharoenvit, Hiroshi Hara, Tohru Hira
- Organizer
  The 9th International Conference on Polyphenols and Health - ICPH2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01473
[Presentation] 肥満誘導食摂取ラットにおけるたんぱく質投与に対するインクレチン分泌の変化2019
- Author(s)
  田中里実，原博，比良徹
- Organizer
  日本アミノ酸学会第13回学術大会
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] 食事誘導性肥満ラットにおける小腸上部と下部での GLP-1 分泌応答の違い2019
- Author(s)
  佐野杏莉、比良徹
- Organizer
  第5回北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05860
[Presentation] 難消化性糖質の消化管内分泌系への作用2018
- Author(s)
  比良　徹、原　博
- Organizer
  第72回日本栄養・食糧学会大会シンポジウム（共催：Hindgut Club Japan）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] 食品成分による消化管内分泌系のコントロール主にGLP-1に関して2018
- Author(s)
  比良　徹
- Organizer
  第98回北海道医学大会生理系分科会・日本生理学会北海道地方会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19158
[Presentation] Postprandial GLP-1 response in Wistar and Goto-Kakizaki rats during diet-induced obesity2018
- Author(s)
  Jukkrapong PINYO, Tohru HIRA, Hiroshi HARA
- Organizer
  Asia-Pacific Diabetes and Obesity Study Group, Joint with the 39th Annual Meeting of Japan Society for the Study of Obesity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] 食品成分による消化管内分泌系のコントロール主にGLP-1に関して2018
- Author(s)
  比良　徹
- Organizer
  第98回北海道医学大会生理系分科会・日本生理学会北海道地方会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] ケルセチン配糖体の長期摂取によるGLP-1分泌能亢進の解析2018
- Author(s)
  長瀬僚介、比良徹、原博
- Organizer
  第 72 回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H01473
[Presentation] 各種ケルセチン配糖体摂取による消化管ホルモン GLP-1 分泌能の適応的増強現象2018
- Author(s)
  長瀬僚介、比良徹、原博
- Organizer
  日本食品科学工学会　第65回大会
- Data Source
  KAKENHI-PROJECT-17H01473
[Presentation] GLP-1を増やす食品成分、食事条件2017
- Author(s)
  比良　徹
- Organizer
  平成２９年度　公益社団法人日本農芸化学会北海道支部第２回講演会および公益社団法人日本栄養・食糧学会　第47回北海道支部大会合同大会
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] Impact of chronic high fat and/or high sucrose feeding on meal-induced GLP-1 secretion2017
- Author(s)
  Jukkrapong PINYO, Tohru HIRA, Hiroshi HARA
- Organizer
  日本農芸化学会　2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] 肥満誘導食摂取ラットにおける食事刺激に対するGLP-1分泌応答の解析2017
- Author(s)
  柳原　くるみ、比良　徹、原　博
- Organizer
  日本栄養・食糧学会第71回大会
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] The role of endogenous GLP-1 against the development of glucose intolerance in rats fed a high fat and high sucrose diet2017
- Author(s)
  Jukkrapong Pinyo, Tohru Hira, Hiroshi Hara
- Organizer
  平成29年度日本農芸化学会北海道支部第１回講演会
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] GLP-1を増やす食品成分、食事条件2017
- Author(s)
  比良　徹
- Organizer
  平成２９年度　公益社団法人日本農芸化学会北海道支部第２回講演会および公益社団法人日本栄養・食糧学会　第47回北海道支部大会合同大会
- Data Source
  KAKENHI-PROJECT-16K14918
[Presentation] たんぱく源の異なる食事による食後ホルモン分泌への影響2016
- Author(s)
  関下まどか、比良徹、原博
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  武庫川女子大学（兵庫県・西宮市）
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] Globulin in the rice endoseprm has potent GLP-1 releasing activity and glucose-lowering effect in rats2016
- Author(s)
  Tohru Hira, Daisuke Inoue, Toshiki Koga, Yuki Ishikawa, Mikio Fujii, Hiroshi Hara
- Organizer
  The 3rd International Conference on Rice Bran Oil (ICRBO 2016)
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都・文京区）
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] Effect of high fat and/or high sucrose diet on meal-induced GLP-1 secretion during the progression of diet induced obesity in rats2016
- Author(s)
  Jukkrapong Pinyo, Tohru Hira, Hiroshi Hara
- Organizer
  平成28年度日本農芸化学会北海道支部第２回講演会
- Place of Presentation
  北海道大学農学部（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] 難消化性デキストリンのチカラ－消化管ホルモンを介した新たな機能－2016
- Author(s)
  比良　徹、原　博
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  武庫川女子大学（兵庫県西宮市）
- Year and Date
  2016-05-13
- Invited
- Data Source
  KAKENHI-PROJECT-16K14918
[Presentation] 食品成分による消化管ホルモン分泌の制御と作用機構2016
- Author(s)
  比良　徹、原　博
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] "肥満誘導食摂取ラットにおけるカナグリフロジン経口投与に対するGLP-1分泌応答 "2016
- Author(s)
  比良徹、古賀俊希、石井伸一、佐々木一代、原博
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン（東京都）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K07725
[Presentation] 血糖調節ペプチド2016
- Author(s)
  比良　徹、原　博
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] D-プシコースの経口投与はラットにおいてGLP-1分泌を促進する2016
- Author(s)
  早川真輝、比良徹、飯田哲郎、岸本由香、原博
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  武庫川女子大学（兵庫県西宮市）
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-16K14918
[Presentation] ラットにおける肥満誘導食へのDFA III、ラフィノース添加の影響2016
- Author(s)
  古賀俊希、比良徹、高橋敬典、名倉泰三、内野浩克、原博
- Organizer
  日本農芸化学会　2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] トウモロコシたんぱく質 Zein を含む食事が与える消化管ホルモン分泌応答への影響2016
- Author(s)
  関下まどか、比良徹、原博
- Organizer
  日本アミノ酸学会　10周年記念大会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都・文京区）
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] 食品成分による消化管ホルモン分泌調節2016
- Author(s)
  比良　徹
- Organizer
  第18回日本神経消化器病学会、第6回IBS研究会、第84回消化器心身医学研究会、第10回機能性ディスペプシア研究会　合同学術集会2016
- Place of Presentation
  北海道大学医学部（北海道・札幌市）
- Year and Date
  2016-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] D-プシコースによる GLP-1 分泌促進作用における糖輸送担体の関与2016
- Author(s)
  早川真輝、比良徹、飯田哲郎、岸本由香、原博
- Organizer
  日本食物繊維学会 21回学術集会
- Place of Presentation
  静岡大学農学部（静岡県静岡市）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K14918
[Presentation] Peptides derived from rice proteins stimulate GLP-1 secretion and suppress blood glucose elevation2016
- Author(s)
  H Hara, Y Ishikawa, M Kadowaki, T Hira
- Organizer
  107th AOCS Annual Meeting
- Place of Presentation
  ソルトレーク（米国）
- Year and Date
  2016-05-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] Effect of resistant maltodextrin and fructooligosaccharides on GLP-1 secretion and production in diet-induced obese rats.2015
- Author(s)
  Ryoya Suto, Tohru Hira, Yuka Kishimoto, Sumiko Kanahori, Hiroshi Hara
- Organizer
  The 12th Asian Congress of Nutrition (12th ACN)
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] 食事誘導性肥満の発症過程におけるGLP-1分泌応答～ラットでの食事負荷試験による解析2015
- Author(s)
  比良　徹
- Organizer
  第21回Hindgut club Japanシンポジウム
- Place of Presentation
  専修大学神田キャンパス（東京都）
- Year and Date
  2015-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] Changes in postprandial glucagon-like peptide-1 secretion during the development of diet-induced obesity in rats2015
- Author(s)
  Tohru Hira, Aoi Kanehira, and Hiroshi Hara
- Organizer
  The 51st EASD Annual Meeting
- Place of Presentation
  Stockholmsmässan、ストックホルム（スウェーデン）
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] トウモロコシ由来ペプチドにおけるGLP-1分泌促進機構の解析2015
- Author(s)
  井上大輔、比良徹、原博
- Organizer
  平成27年度日本農芸化学会北海道支部第２回講演会
- Place of Presentation
  北海道大学学術交流会館（北海道・札幌市）
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] トウモロコシたんぱく質Zeinを含む食事の摂食による食後GLP-1分泌への影響2015
- Author(s)
  関下まどか、比良徹、原博
- Organizer
  日本栄養・食糧学会東北支部会（第49回大会）、北海道支部会（第45回大会）合同支部会
- Place of Presentation
  東北大学農学部（雨宮キャンパス）（宮城県・仙台市）
- Year and Date
  2015-10-25
- Data Source
  KAKENHI-PROJECT-26252016
[Presentation] 食事誘導性肥満モデルラットにおける食後GLP-1分泌応答2015
- Author(s)
  比良　徹
- Organizer
  第２７回夏期油脂・コレステロール研究会
- Place of Presentation
  エーヴランドホテル（北海道・余市町）
- Year and Date
  2015-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] Supplementation of resistant maltodextrin and fructooligosaccharides promotes GLP-1 production, attenuates lipid accumulation and glucose intolerance in high fat and high sucrose diet-induced obese rats2015
- Author(s)
  Tohru Hira, Ryoya Suto, Yuka Kishimoto, Sumiko Kanahori, Hiroshi Hara
- Organizer
  The 6th International Dietary Fibre Conference 2015 (DF15)
- Place of Presentation
  Les Salons de l'Aveyron、パリ（フランス）
- Year and Date
  2015-06-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] 長期高脂肪・高ショ糖食摂取による絶食時および食後 GLP-1分泌への影響2014
- Author(s)
  金平葵、比良徹、原博
- Organizer
  第68回日本栄養・食糧学会大
- Place of Presentation
  酪農学園大学（北海道江別市）
- Year and Date
  2014-06-01
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] Effects of resistant maltodextrin and fructooligosaccharides on fasting GLP-1 levels and glucose tolerance in rats2014
- Author(s)
  Tohru Hira, Asuka Ikee, Yuka Kishimoto, Sumiko Kanahori, Hiroshi Hara
- Organizer
  10th Vahouny Dietary Fiber Symposium, The American Society for Nutrition and NutraSource, Inc
- Place of Presentation
  Marriott Bethesda North, Bethesda, USA
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] trans,trans-2,4-デカジエナールの経口投与によるラット胃排出遅延作用2014
- Author(s)
  矢萩明日香、比良徹、西山千草、山下貴稔、今義潤、原博
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス(川崎市)
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 高脂肪・高ショ糖食ラットにおける食後GLP-1分泌の解析2014
- Author(s)
  金平葵、比良徹、原博
- Organizer
  第35回日本肥満学会
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター（宮崎市）
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] PHYSIOLOGICAL FUNCTIONS OF SOYBEAN PEPTIDES, Diversity of physionlogical functions of amino acids and peptide2013
- Author(s)
  Hara H; Nakajima S; Hira T
- Organizer
  20th International Congress of Nutrition (ICN2013)
- Place of Presentation
  Granada Congress, Granada, Spain
- Year and Date
  2013-09-16
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] トウモロコシペプチドによるinvivo、invitroでのGLP-1分泌作用2013
- Author(s)
  山田菜央、比良徹、原博
- Organizer
  日本アミノ酸学会
- Place of Presentation
  熊本市医師会館(熊本市)
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ラットにおいてトウモロコシペプチドの経口投与が、インクレチン分泌促進を介して血糖上昇を抑制する2013
- Author(s)
  比良　徹、樋口謹行、原博
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  テトリア熊本ビル、熊本市
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Fructooligosaccharides augments the effect of a flavonoid, a-glucosyl-isoquercitrin, on glucagon-like peptide 1 secretion2013
- Author(s)
  P. Phuwamongkolwiwat, T. Hira and H. Hara
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston Convention & Exibition Center, Boston, USA
- Year and Date
  2013-04-21
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] ポリリジンはラット腸管において胃排出を遅延し、血糖値上昇を抑制する2013
- Author(s)
  佐藤恵理、比良徹、満永有美、中島進吾、江藤譲、原博
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学(名古屋市)
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 難消化性糖質摂取ラットにおける食品ペプチド経口投与に対するGLP-1分泌2013
- Author(s)
  池江明日香、比良徹、岸本由香、原博
- Organizer
  日本食物繊維学会18回学術集会
- Place of Presentation
  仁愛大学(福井県越前市)
- Year and Date
  2013-11-24
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 難消化性糖質摂取ラットにおける食品ペプチド経口投与に対する GLP-1 分泌2013
- Author(s)
  池江　明日香、比良　徹、岸本由香、原　博
- Organizer
  日本食物繊維学会 18回学術集会
- Place of Presentation
  仁愛大学、福井県越前市
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] PHYSIOLOGICAL FUNCTIONS OF SOYBEAN PEPTIDES, Diversity of physionlogical functions of amino acids and peptide2013
- Author(s)
  Hara H; Nakajima S; Hira T
- Organizer
  20th International Congress of Nutrition (ICN2013)
- Place of Presentation
  Granada Congress, Granada, Spain
- Year and Date
  2013-09-16
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Activation of gut calcium-sensing receptor by peptide agonists promotes glucose tolerance in rats2013
- Author(s)
  T. Hira, M. Muramatsu, A. Mitsunaga, E. Sato, S. Nakajima, Y. Kitahara, Y. Eto and H. Hara
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston Convention & Exibition Center, Boston (US)
- Year and Date
  2013-04-23
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ラットにおいて難消化性デキストリンの長期摂取は血中GLP-1濃度を高める2013
- Author(s)
  池江明日香、比良徹、岸本由香、原博
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学(名古屋市)
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 難消化性デキストリン摂取は、ラット血中GLP-1濃度を高め、耐糖能を改善する2013
- Author(s)
  池江明日香、比良徹、岸本由香、原博
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京フォーラム(東京)
- Year and Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] ラットにおいて難消化性デキストリンの長期摂取は血中GLP-1濃度を高める"2013
- Author(s)
  池江　明日香、比良　徹、岸本由香、原　博
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学、名古屋市
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 消化管内分泌細胞株において不飽和アルデヒドはTRPA1を介してCCK分泌を誘導する2013
- Author(s)
  中島進吾、比良徹、西山千草、山下貴俊、今義潤、原博
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学(仙台)
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] "難消化性デキストリン摂取は、ラット血中GLP-1濃度を高め、耐糖能を改善する "2013
- Author(s)
  池江　明日香、比良　徹、岸本由香、原　博
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京フォーラム、東京
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] ラットにおいてtrans,trans-2,4-デカジエナールの経口投与は胃排出を抑制する2013
- Author(s)
  矢萩明日香、比良徹、西山千草、山下貴稔、今義潤、原博
- Organizer
  第43回日本栄養・食糧学会北海道支部会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2013-10-26
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ラットにおいてトウモロコシペプチドの経口投与が、インクレチン分泌促進を介して血糖上昇を抑制する2013
- Author(s)
  比良徹、樋口謹行、原博
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  テトリア熊本ビル(熊本市)
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 食品ペプチドの消化管での作用を介した血糖制御に関する研究2013
- Author(s)
  比良徹
- Organizer
  2013年度日本アミノ酸学会科学・技術賞受賞講演、日本アミノ酸学会
- Place of Presentation
  熊本市医師会館(熊本市)
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Fructooligosaccharides augments the effect of a flavonoid, a-glucosyl-isoquercitrin, on glucagon-like peptide 1 secretion.2013
- Author(s)
  P. Phuwamongkolwiwat, T. Hira and H. Hara
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston Convention & Exibition Center, Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] ラットにおいてトウモロコシペプチドの経口投与が、インクレチン分泌促進を介して血糖上昇を抑制する2013
- Author(s)
  比良徹、樋口謹行、原博
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  テトリア熊本ビル(熊本市)
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 食品ペプチドの消化管での作用を介した血糖制御に関する研究2013
- Author(s)
  比良徹
- Organizer
  2013年度日本アミノ酸学会科学・技術賞受賞講演、日本アミノ酸学会
- Place of Presentation
  熊本市医師会館(熊本市)
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ラットにおいて、ポリリジンの経口投与は胃排出を遅延して血糖上昇を抑制する2012
- Author(s)
  比良　徹、満永有美、佐藤　恵理、中島　進吾、江藤　譲、原博
- Organizer
  第33回日本肥満学会
- Place of Presentation
  ホテルグランヴィア京都（京都市）
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ラットにおいて、ポリリジンの経口投与は胃排出を遅延して血糖上昇を抑制する2012
- Author(s)
  比良徹、満永有美、佐藤恵理、中島進吾、江藤譲、原博
- Organizer
  第33回日本肥満学会
- Place of Presentation
  ホテルグランヴィア京都(京都)
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] Fructooligosaccharides enhance bene?cial effects of a?avonoid, quercetin-3-glucoside, on insulin sensitivity in rats fed high sucrose diet2012
- Author(s)
  P Phuwamongkolwiwat, T Suzuki, T Hira and H Hara
- Organizer
  Experimental Biology 2012
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2012-04-23
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 消化管内分泌細胞におけるカゼインによるCCK分泌機構の解析2012
- Author(s)
  後藤健仁、比良徹、中島進吾、原博
- Organizer
  日本農芸化学会　2012年度大会
- Place of Presentation
  京都女子大学（京都市）
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 腸管での栄養素認識と消化管ホルモン分泌に関する研究2012
- Author(s)
  比良　徹
- Organizer
  平成24年度日本栄養・食糧学会奨励賞　受賞講演
- Place of Presentation
  東北大学川内萩ホール（仙台市）
- Invited
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 難消化性デキストリンの単回及び長期摂取はラットのGLP-1分泌を促進する2012
- Author(s)
  池江明日香、比良徹、岸本由香、原博
- Organizer
  日本食物繊維学会17回学術集会
- Place of Presentation
  中村学園大学(福岡市)
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] トウモロコシZein加水分解物の経口投与はインクレチン分泌を介して血糖上昇を抑制する2012
- Author(s)
  樋口謹行、比良徹、原博
- Organizer
  第66回日本栄養・食糧学会大会
- Place of Presentation
  東北大学(仙台市)
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 異なる分子量の食品ペプチドがカルシウム感知受容体を介したCholecystokinin分泌を誘導する2012
- Author(s)
  中島進吾、比良徹、原博
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(京都)
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] Wheat gluten hydrolysate induces PYY secretion and suppresses food intake in rats2012
- Author(s)
  Wenya Chen, Tohru Hira, Hiroshi Hara
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(京都)
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 消化管内分泌細胞におけるカゼインによるCCK分泌機構の解析2012
- Author(s)
  後藤健仁、比良徹、中島進吾、原博
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(京都)
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 難消化性デキストリンのラット腸管におけるGLP-1分泌作用の検討2012
- Author(s)
  池江明日香、比良徹、岸本由香、原博
- Organizer
  第66回日本栄養・食糧学会大会
- Place of Presentation
  東北大学(仙台市)
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 腸管での食品ペプチド認識と消化管ホルモン分泌に関する研究2012
- Author(s)
  比良　徹
- Organizer
  日本農芸化学会北海道支部平成24年度支部講演会　特別講演
- Place of Presentation
  北海道大学農学部（札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 難消化性デキストリンのGLP-1分泌作用の検討2011
- Author(s)
  池江　明日香、比良　徹、岸本由香、原　博
- Organizer
  第65回日本栄養・食糧学会大会
- Place of Presentation
  お茶の水女子大学（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] トウモロコシ Zein 加水分解物はラットへの経口投与によりインクレチン分泌を介して血糖上昇を抑制する2011
- Author(s)
  樋口謹行、比良徹、原博
- Organizer
  第65回日本栄養・食糧学会大会
- Place of Presentation
  お茶の水女子大学（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Potato extract (Potein) suppresses food intake via CCK release in rats2011
- Author(s)
  Wenya Chen, Shingo Nakajima, Tohru Hira, Rika Nagamine, Hiroshi Tomozawa, Kinya Takagaki, Hiroshi Hara
- Organizer
  2011 The International Conference on Food Factors
- Place of Presentation
  Taipei International Convention Center,台北(台湾)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] トウモロコシたんぱく質 Zein の加水分解物による血糖上昇抑制への GLP-1 の関与2011
- Author(s)
  樋口謹行，比良　徹，原　博
- Organizer
  日本食物繊維学会 16 回学術集会
- Place of Presentation
  独立行政法人国立健康・栄養研究所（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] ビール酵母抽出物中のCCK分泌促進ペプチドの探索とラットでの食欲抑制作用2011
- Author(s)
  須田和希、比良徹、KAOSAR SUFIAN、原博
- Organizer
  第65回日本栄養・食糧学会大会
- Place of Presentation
  お茶の水女子大学(東京)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] Calcium-sensing receptorアゴニストによる血糖上昇抑制とその作用機構の解明2011
- Author(s)
  比良徹、村松茉耶、江藤譲、原博
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路夢舞台国際会議場(淡路市)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] Oral preload of a grain peptone enhances PYY secretion and suppresses food intake in rats2011
- Author(s)
  Wenya Chen, Tohru Hira, Hiroshi Hara
- Organizer
  International Society for Nutraceuticals and Functional Foods 2011
- Place of Presentation
  ロイトン札幌ホテル(札幌市)
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ビール酵母抽出物中のCCK分泌促進ペプチドの探索2011
- Author(s)
  須田和希、比良徹、原博
- Organizer
  日本アミノ酸学会第5回学術大会
- Place of Presentation
  名古屋大学シンポジオン(名古屋市)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] トウモロコシたんぱく質Zeinの加水分解物による血糖上昇抑制へのGLP-1の関与2011
- Author(s)
  樋口謹行,比良徹,原博
- Organizer
  日本食物繊維学会16回学術集会
- Place of Presentation
  独立行政法人国立健康・栄養研究所(東京都)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 難消化性デキストリンのGLP-1分泌作用の検討2011
- Author(s)
  池江明日香、比良徹、岸本由香、原博
- Organizer
  第41回日本栄養・食糧学会北海道支部会
- Place of Presentation
  天使大学(札幌市)
- Year and Date
  2011-10-23
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Oral and duodenal administration of calcium-sensing receptor antagonists improve glucose tolerance in rats2011
- Author(s)
  Tohru Hira, Maya Muramatsu, Yusuru Eto, Hiroshi Hara
- Organizer
  2011 The International Conference on Food Factors
- Place of Presentation
  Taipei International Convention Center,台北(台湾)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] トウモロコシZein加水分解物はラットへの経口投与によりインクレチン分泌を介して血糖上昇を抑制する2011
- Author(s)
  樋口謹行、比良徹、原博
- Organizer
  第65回日本栄養・食糧学会大会
- Place of Presentation
  お茶の水女子大学(東京都)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Calcium-sensing receptorはCCK産生細胞における食品ペプチド受容体として多様なペプチドを認識する2011
- Author(s)
  中島進吾,比良徹,Sufian Kaosar,江藤譲,原博
- Organizer
  第65回日本栄養・食糧学会大会
- Place of Presentation
  お茶の水女子大学(東京)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 難消化性デキストリンは消化管内分泌細胞に直接作用して GLP-1 分泌を促進する2011
- Author(s)
  池江明日香、比良　徹、岸本由香、原　博
- Organizer
  日本食物繊維学会 16 回学術集会
- Place of Presentation
  独立行政法人国立健康・栄養研究所（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 難消化性デキストリンは消化管内分泌細胞に直接作用してGLP-1分泌を促進する2011
- Author(s)
  池江明日香、比良徹、岸本由香、原博
- Organizer
  日本食物繊維学会16回学術集会
- Place of Presentation
  独立行政法人国立健康・栄養研究所(東京都)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 食品ペプチドによる消化管ホルモン分泌について～消化管の栄養素受容機構2010
- Author(s)
  比良徹
- Organizer
  Hindgut Clubサテライトミーティング(第64回日本栄養・食糧学会関連学術集会)
- Place of Presentation
  アスティ徳島(徳島県) 招待講演
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 食品ペプチドによる消化管ホルモン分泌について?消化管の栄養素受容機構2010
- Author(s)
  比良徹
- Organizer
  Hindgut Clubサテライトミーティング(第64回日本栄養・食糧学会関連学術集会)
- Place of Presentation
  アスティ徳島(徳島県)
- Year and Date
  2010-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Corn protein hydrolysate stimulates GLP-1 secretion and attenuates hyperglycaemia in rats2010
- Author(s)
  T. Hira, T. Mochida, H. Hara
- Organizer
  The 18th International Symposium on Regulatory Peptides
- Place of Presentation
  Europa Hotel Belfast (Belfast, UK)
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] ラットにおけるトウモロコシたんぱく加水分解物の経口投与による血糖上昇抑制2010
- Author(s)
  樋口謹行、比良徹、原博
- Organizer
  第8回日本栄養改善学会北海道支部学術総会
- Place of Presentation
  天使大学(札幌)
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] Calcium-sensing receptor is a sensor for dietary peptides to stimulate cholecystokinin secretion in the enteroendocrine cell line STC-12010
- Author(s)
  Shingo Nakajima、Tohru Hira、Md Kaosar, Niaz Bin Sufian, Yuzuru Eto、Hiroshi Hara
- Organizer
  The 18th International Symposium on Regulatory Peptides
- Place of Presentation
  Europa Hotel Belfast (Belfast, UK)
- Data Source
  KAKENHI-PROJECT-21780118
[Presentation] パラチノースによるGLP-1分泌促進機構の解析2010
- Author(s)
  比良徹、村松茉耶、奥野雅浩、原博
- Organizer
  第31回日本肥満学会
- Place of Presentation
  前橋テルサ(群馬県)
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] CCK産生細胞においてCalcium-sensing receptorはペプトン受容体として機能する2010
- Author(s)
  中島進吾、比良徹、Sufian Kaosar、江藤譲、原博
- Organizer
  第64回日本栄養・食糧学会大会
- Place of Presentation
  アスティ徳島(徳島県)
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-21780118
[Presentation] leal administration of zein hydrolysate stimulates glucagon-like peptide-1 secretion and attenuates hyperglycaemia induced by intraperitoneal glucose administration in rats2010
- Author(s)
  Tohru Hira, Taisuke Mochida, Hiroshi Hara
- Organizer
  The Physiological Society, Metabolism & Endocrinology Themed Meeting including a focused symposium : "Towards an Understanding of the Enteroendocrine System"
- Place of Presentation
  AstraZeneca Pharmaceuticals (Macclesfield, UK)
- Year and Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] ラットにおけるトウモロコシZein加水分解物によるGLP-1分泌を介した血糖上昇抑制2010
- Author(s)
  比良徹、持田泰輔、原博
- Organizer
  日本アミノ酸学会第4回学術大会
- Place of Presentation
  ホテルサンシャイン鬼怒川(栃木県)
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] トウモロコシZein加水分解物はラットへの経口投与により血糖上昇を抑制する2010
- Author(s)
  樋口謹行、比良徹、原博
- Organizer
  第40回日本栄養・食糧学会北海道支部会
- Place of Presentation
  天使大学(札幌)
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] トウモロコシZein加水分解物はラット腸管においてGLP-1分泌を刺激して血糖上昇を抑制する2009
- Author(s)
  持田泰佑、比良徹、原博
- Organizer
  第63回日本栄養・食糧学会大会
- Place of Presentation
  長崎ブリックホール(長崎県)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] ラットにおいて Protamine 経口投与は血糖上昇を抑制する2009
- Author(s)
  村松茉耶、比良徹、江藤譲、原博
- Organizer
  平成21年度第二回合同学術講演会
- Place of Presentation
  帯広市十勝プラザ
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21780118
[Presentation] トウモロコシZein加水分解物はラット腸管においてGLP-1 分泌を刺激して血糖上昇を抑制する2009
- Author(s)
  持田泰佑、比良徹、原博
- Organizer
  第63回日本栄養・食糧学会大会
- Place of Presentation
  長崎ブリックホール(長崎県)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] 消化管内分泌細胞株におけるトウモロコシZein加水分解物による消化管ホルモンGlucagon-likepeptide-1分泌機構2009
- Author(s)
  川村侑輝、比良徹、原博
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  マリンメッセ福岡(福岡市)
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] ビール酵母中に含まれる消化管ホルモンCCK 分泌活性を持つペプチドの探索2009
- Author(s)
  須田和希、比良徹、Kaosar SUFIAN、原博
- Organizer
  第39回日本栄養・食糧学会北海道支部会
- Place of Presentation
  北翔大学北方圏学術情報センター「ポルト」(札幌市)
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] 消化管内分泌細胞株におけるトウモロコシZein加水分解物による消化管ホルモンGlucagon-like peptide-1分泌機構2009
- Author(s)
  川村侑輝、比良徹、原博
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡市マリンメッセ福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] ビール酵母中に含まれる消化管ホルモンCCK分泌活性を持つペプチドの探索2009
- Author(s)
  須田和希、比良徹、Kaosar SUFIAN、原博
- Organizer
  第39回日本栄養・食糧学会北海道支部会
- Place of Presentation
  北翔大学北方圏学術情報センター「ポルト」(札幌市)
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] ラットにおいてProtamine経口投与は血糖上昇を抑制する2009
- Author(s)
  村松茉耶、比良徹、江藤譲、原博
- Organizer
  平成21年度第二回合同学術講演会
- Place of Presentation
  帯広市十勝プラザ(帯広市)
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21780118
[Presentation] 消化管内分泌細胞株GLUTagにおける、トウモロコシペプチドによる消化管ホルモンGlucagon-like peptide-1分泌機構2008
- Author(s)
  川村侑輝、比良徹、原博
- Organizer
  平成20年度第二回合同学術講演会(日本農芸化学会北海道支部、日本栄養食糧学会北海道支部合同開催)
- Place of Presentation
  帯広市十勝プラザ
- Year and Date
  2008-11-09
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] トウモロコシZein加水分解物は、ラット腸管で内分泌細胞への直接的、間接的作用によりGlucagon-like peptide-1分泌を刺激する2008
- Author(s)
  持田泰佑、比良徹、原博
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名城大学天白キャンパス(愛知県)
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] Direct and indirect stimulation of Glucagone-like peptide-1 secretion by dietary protein hydrolysate in the rat duodenum and ileum2008
- Author(s)
  Tohru Hira, Taisuke Mochida, Kyoko Miyashita, and Hiroshi Hara
- Organizer
  22nd Meeting of European Intestinal Transport Group (EITG 2008)
- Place of Presentation
  スペインパンプローナ市University of Navara
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] Direct and indirect stimulation of Glucagone-like peptide-1 secretion by dietary protein hydrolysate in the rat duodenum and ileum2008
- Author(s)
  Tohru Hira, Taisuke Mochida, Kyoko Miyashita, Hiroshi Hara
- Organizer
  22nd Meeting of European Intestinal Transport Group (EITG 2008)
- Place of Presentation
  University of Navara(スペインパンプローナ市)
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] 消化管内分泌細胞株GLUTagにおける、トウモロコシペプチドによる消化管ホルモンGlucagon-like peptide-1分泌機構2008
- Author(s)
  川村侑輝、比良徹、原博
- Organizer
  平成20年度第二回合同学術講演会(日本農芸化学会北海道支部、日本栄養・食糧学会北海道支部合同開催)
- Place of Presentation
  十勝プラザ(帯広市)
- Year and Date
  2008-11-09
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] Beer yeast (S. cerevisiae) peptides potently stimulate cholecystokinin secretion from enteroendocrin2008
- Author(s)
  Sufian Kaosar, Tohru Hira, Osamu Kanauchi, Hiroshi Hara
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名城大学天白キャンパス
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] トウモロコシ Zein 加水分解物は、ラット腸管で内分泌細胞への直接的、間接的作用により Glucagon-like peptide-1分泌を刺激する2008
- Author(s)
  持田泰佑, 比良徹, 原博
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名城大学天白キャンパス
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] Beer yeast (S. cerevisiae) peptides potently stimulate cholecystokinin secretion from enteroendocrine STC-1 cells2008
- Author(s)
  Sufian Kaosar, Tohru Hira, Osamu Kanauchi, Hiroshi Hara
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名城大学天白キャンパス(愛知県)
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] トウモロコシの難消化性たんぱく質Zeinの加水分解物によるラットにおけるGlucagon-likepeptide-1分泌機構2008
- Author(s)
  持田泰佑、比良徹、原博
- Organizer
  第13回日本食物繊維学会学術集会
- Place of Presentation
  国立健康・栄養研究所(東京都)
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] トウモロコシの難消化性たんぱく質Zeinの加水分解物によるラットにおけるGlucagon-like peptide-1分泌機構2008
- Author(s)
  持田泰佑、比良徹、原博
- Organizer
  第13回日本食物繊維学会学術集会
- Place of Presentation
  東京都国立健康・栄養研究所
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] ラット腸管においてトウモロコシZein加水分解物は、内分泌細胞への直接的、間接的作用により消化管ホルモン Glucagon-like peptide-1分泌を刺激する2007
- Author(s)
  持田泰佑, 比良徹, 原博
- Organizer
  平成19年度第二回合同学術講演会(日本農芸化学会北海道支部、日本栄養・食糧学会北海道支部、他)
- Place of Presentation
  東京農業大学生物産業学部
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] 腸管においてトウモロコシZein加水分解物は、内分泌細胞への直接的、間接的作用により消化管ホルモンGlucagon-like peptide-1分泌を刺激する2007
- Author(s)
  持田泰佑、比良徹、原博
- Organizer
  平成19年度第二回合同学術講演会(日本農芸化学会北海道支部、日本栄養・食糧学会北海道支部、他)
- Place of Presentation
  東京農業大学生物産業学部(網走市)
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19380071
[Presentation] Effects of resistant maltodextrin and fructooligosaccharides on fasting GLP-1 levels and glucose tolerance in rats
- Author(s)
  Tohru Hira, Asuka Ikee, Yuka Kishimoto, Sumiko Kanahori, Hiroshi Hara
- Organizer
  10th Vahouny Dietary Fiber Symposium
- Place of Presentation
  Marriott Bethesda North, Bethesda, USA
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 長期高脂肪・高ショ糖食摂取による絶食時および食後 GLP-1分泌への影響
- Author(s)
  金平葵、比良徹、原博
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学、北海道江別市
- Data Source
  KAKENHI-PROJECT-25450159
[Presentation] PHYSIOLOGICAL FUNCTIONS OF SOYBEAN PEPTIDE
- Author(s)
  Hara H; Nakajima S; Hira T
- Organizer
  20th International Congress of Nutrition (ICN2013)
- Place of Presentation
  Granada Congress Center, Granada, Spain
- Invited
- Data Source
  KAKENHI-PROJECT-22380070
[Presentation] 食品ペプチドによるGLP-1分泌を介した血糖上昇抑制
- Author(s)
  比良徹
- Organizer
  "2013年度生理学研究所研究会『上皮膜輸送の多層的コントロールによる生体の恒常性維持機構』
- Place of Presentation
  自然科学研究機構　生理学研究所、愛知県岡崎市
- Invited
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] "Activation of gut calcium-sensing receptor by peptide agonists promotes glucose tolerance in rats"
- Author(s)
  T. Hira, M. Muramatsu, A. Mitsunaga, E. Sato, S. Nakajima, Y. Kitahara, Y. Eto and H. Hara.
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston Convention & Exibition Center, Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ポリリジンはラット腸管において胃排出を遅延し、血糖値上昇を抑制する
- Author(s)
  佐藤恵理、比良徹、満永有美、中島進吾、江藤譲、原博
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学、名古屋市
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] ラットにおいてトウモロコシペプチドの経口投与が、インクレチン分泌促進を介して血糖上昇を抑制する
- Author(s)
  比良　徹、樋口謹行、原博
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  テトリア熊本ビル、熊本市
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] 食品ペプチドの消化管での作用を介した血糖制御に関する研究
- Author(s)
  比良徹
- Organizer
  日本アミノ酸学会
- Place of Presentation
  熊本市医師会館、熊本市
- Invited
- Data Source
  KAKENHI-PROJECT-23780124
[Presentation] trans,trans-2,4-デカジエナールの経口投与によるラット胃排出遅延作用
- Author(s)
  矢萩明日香、比良徹、西山千草、山下貴稔、今義潤、原博
- Organizer
  日本農芸化学会　2014年度大会
- Place of Presentation
  明治大学生田キャンパス、川崎市
- Data Source
  KAKENHI-PROJECT-23780124

1. HARA Hiroshi (70198894)

# of Collaborated Projects: 6 results

# of Collaborated Products: 94 results
2. ISHIZUKA Satoshi (00271627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. INUI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. HARADA Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 吉田藍子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 乾隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hira Tohru 比良 徹

HIRA Tohru 比良 徹

Research Projects

Research Products

Co-Researchers

GLP-1分泌促進と分解抑制の両作用を併せ持つペプチドの創生Principal Investigator

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Protective mechanisms of enteroendocrine systems against diet-induced obesity and glucose intolerancePrincipal Investigator

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Mechanisms underlying enhanced GLP-1 response in diet-induced obesityPrincipal Investigator

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Study on postprandial nutrient and gut hormone responses in different intestinal regions

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Study on physiological effects of isomalto-megalo-saccharides

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Regulation of gut nutrient sensing mechanisms in response to dietary interventionPrincipal Investigator

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Study on sensing mechanism of low-digestible saccharides in nutrient-sensing enteroendocrine cells

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Study on enteroendocrine, nervous and reproductive systems related to diet for preventing metabolic diseases.

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Role of GLP-1 during the development of diet-induced obesity and glucose impairmentPrincipal Investigator

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Elucidation of mechanisms to avoid chronic inflammation via enteroendocrine system: relationships between immune cells and adipocytes

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Searching for dietary protein/peptide sensing receptors in enteroendocrine cellsPrincipal Investigator

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Enhancement of dietary peptide-induced GLP-1 secretion by indigestible saccharides

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Role of CaSR as dietary peptide sensor and search for dietary protein receptor in the gutPrincipal Investigator

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Hira Tohru 比良徹

HIRA Tohru 比良徹