Tachikawa Ai 立川愛

… Alternative Names

TACHIKAWA Ai 立川愛

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Researcher Number	10396880
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所エイズ研究センター, 室長
Affiliation (based on the past Project Information) *help	2014 – 2023: 国立感染症研究所, エイズ研究センター, 室長 2016: 国立感染症研究所, その他部局等, 室長 2014 – 2016: 国立感染症研究所, エイズ研究センター第二室, 室長 2011 – 2013: 東京大学, 医科学研究所, 准教授 2010 – 2011: 東京大学, 医科学研究所, 助教 2008: 東京大学, 医科学研究所., 助教 2007 – 2008: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Applied health science / Medium-sized Section 58:Society medicine, nursing, and related fields / Studies on the Super-Aging Society / Infectious disease medicine / Virology Except Principal Investigator Infectious disease medicine / Obstetrics and gynecology / Virology
Keywords	Principal Investigator 免疫老化 / HIV感染症 / T細胞 / TCRレパトア / 感染症 / HIV / CTL / デングウイルス / 感染免疫 / ウイルス感染症 … More / TCRレパートリー / 免疫力評価 / 感染症予防 / T細胞免疫 / TCR / 免疫多様性 / COVID-19 / T細胞免疫応答 / 慢性ウイルス感染 / DNAメチル化 / エピジェネティクス / 持続感染 / T細胞応答 / 慢性ウイルス感染症 / 抗原特異的CTL / 免疫細胞療法 / iPS細胞 / 細胞性傷害性T細胞 / ウイルス / 細胞性免疫 / 獲得免疫応答 / エスケープ変異 / 抗原提示 / HIV 感染症 / 病原性 … More Except Principal Investigator HIV / 東南アジア / 国際情報交換 / ウィルス再活性化 / 日和見感染症 / サイトカイン / HHV-6 / サイトメガロウィルス / 造血幹細胞移植 / 再活性化 / ヘルペスウィルス / 粘膜リンパ球 / 再生医療 / エフェクター細胞療法 / HPV E7特異的細胞傷害性T細胞 / ヒトパピローマウイルス / リザーブ細胞 / T-iPS細胞 / メタボローム解析 / 免疫療法 / HPV / 子宮頸部組織幹細胞 / 癌幹細胞 / T-iPS / リプログラミング / iPS技術 / 癌免疫療法 / 子宮頸癌 / タイ王国 / 分子疫学 / パピローマウイルス / 男性同性愛者 / 肛門癌 / 臨床 / 内科 / 免疫学 / ウイルス / 感染症 / 複製能力 / 進化 / 感染症防御学 / HIV病態進行 / TCR レパートリー / T細胞受容体(TCR) / 細胞傷害性T細胞(CTL) / エピトープ / 抗原認識 / 細胞傷害性T 細胞 (CTL) / HLA Less

Research for infection immunity against global viral infections with a new bioinformatic approachPrincipal Investigator
- Principal Investigator
  
  立川愛
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Institute of Infectious Diseases
感染症に対する免疫力評価系の構築Principal Investigator
- Principal Investigator
  
  立川愛
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  National Institute of Infectious Diseases
Study of Immune agingPrincipal Investigator
- Principal Investigator
  
  Tachikawa Ai
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  National Institute of Infectious Diseases
Analysis of T cells in immunological agingPrincipal Investigator
- Principal Investigator
  
  TACHIKAWA AI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  National Institute of Infectious Diseases
Identification of reactivation factors for human herpes viruses
- Principal Investigator
  
  SEO SACHIKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  National Cancer Center Japan
Basic research for development of immunotherapy for cervical cancer by using regenerative medicine (induced pluripotent stem cell: iPS cell)
- Principal Investigator
  
  KAWANA Kei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University
  The University of Tokyo
Development of immunotherapy for HIV curePrincipal Investigator
- Principal Investigator
  
  Tachikawa Ai
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  National Institute of Infectious Diseases
  The University of Tokyo
Molecular Epidemiology of HPV and HBV in men who have sex with men in South East Asia
- Principal Investigator
  
  MIURA TOSHIYUKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagasaki University
Investigation of change in HIV-1 replication capacityover the epidemic
- Principal Investigator
  
  MIURA Toshiyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagasaki University
  The University of Tokyo
Influence of HIV protein kinetics on anti-HIV effects in HIV-specific cellular immune responsePrincipal Investigator
- Principal Investigator
  
  TACHIKAWA Ai
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Analysis of HIV-specific cellular immune response and antigen presentation in HIV infection
- Principal Investigator
  
  IWAMOTO Aikichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo

[Journal Article] Multimodal single-cell analyses of peripheral blood mononuclear cells of COVID-19 patients in Japan2023
- Author(s)
  Kashima Yukie、Mizutani Taketoshi、Nakayama-Hosoya Kaori、Moriyama Saya、Matsumura Takayuki、Yoshimura Yoshihiro、Sasaki Hiroaki、Horiuchi Hiroshi、Miyata Nobuyuki、Miyazaki Kazuhito、Tachikawa Natsuo、Takahashi Yoshimasa、Suzuki Tadaki、Sugano Sumio、Matano Tetsuro、Kawana-Tachikawa Ai、Suzuki Yutaka
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-28696-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20498
[Journal Article] Breadth and Durability of SARS-CoV-2-Specific T Cell Responses following Long-Term Recovery from COVID-192023
- Author(s)
  Dang Thi Thu Thao、Anzurez Alitzel、Nakayama-Hosoya Kaori、Miki Shoji、Yamashita Kazuo、de Souza Mark、Matano Tetsuro、Kawana-Tachikawa Ai
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 4
- DOI
  10.1128/spectrum.02143-23
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20498, KAKENHI-PROJECT-21H02745
[Journal Article] Impaired protective role of HLA-B*57:01/58:01 in HIV-1 CRF01_AE infection: a cohort study in Vietnam2023
- Author(s)
  Minh Tam Tran Thi、Hikichi Yuta、Miki Shoji、Imanari Yuriko、Kusagawa Shigeru、Okazaki Midori、Thu Thao Dang Thi、Shiino Teiichiro、Matsuoka Saori、Yamamoto Hiroyuki、Ohashi Jun、Hall William W.、Matano Tetsuro、Thi Lan Anh Nguyen、Kawana-Tachikawa Ai
- Journal Title
  
  International Journal of Infectious Diseases
  
  Volume: 128 Pages: 20-31
- DOI
  10.1016/j.ijid.2022.12.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20498
[Journal Article] Super high-resolution single-molecule sequence-based typing of HLA class I alleles in HIV-1 infected individuals in Ghana2022
- Author(s)
  Nii-Trebi Nicholas I.、Matsuoka Saori、Kawana-Tachikawa Ai、Bonney Evelyn Y.、Abana Christopher Z.、Ofori Sampson B.、Mizutani Taketoshi、Ishizaka Aya、Shiino Teiichiro、Ohashi Jun、Naruse Taeko K.、Kimura Akinori、Kiyono Hiroshi、Ishikawa Koichi、Ampofo William K.、Matano Tetsuro
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 6 Pages: e0269390-e0269390
- DOI
  10.1371/journal.pone.0269390
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06993, KAKENHI-PROJECT-20K20498, KAKENHI-PROJECT-21H02745, KAKENHI-PROJECT-18H05280
[Journal Article] Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors2022
- Author(s)
  Ma Keke、Chai Yan、Guan Jiawei、Tan Shuguang、Qi Jianxun、Kawana-Tachikawa Ai、Dong Tao、Iwamoto Aikichi、Shi Yi、Gao George F.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 209 Issue: 9 Pages: 1652-1661
- DOI
  10.4049/jimmunol.2200191
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20498
[Journal Article] Sustainable Antiviral Efficacy of Rejuvenated HIV-Specific Cytotoxic T Lymphocytes Generated from Induced Pluripotent Stem Cells2022
- Author(s)
  Miki Shoji、Kawai Yohei、Nakayama-Hosoya Kaori、Iwabuchi Ryutaro、Terahara Kazutaka、Tsunetsugu-Yokota Yasuko、Koga Michiko、Matano Tetsuro、Kaneko Shin、Kawana-Tachikawa Ai
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 6
- DOI
  10.1128/jvi.02217-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20498
[Journal Article] Generation of highly proliferative, rejuvenated cytotoxic T cell clones through pluripotency reprogramming for adoptive immunotherapy2021
- Author(s)
  Yohei Kawai, Ai Kawana-Tachikawa, Shuichi Kitayama, Tatsuki Ueda, Shoji Miki, Akira Watanabe and Shin Kaneko
- Journal Title
  
  Molecular Therapy
  
  Volume: 29 Issue: 10 Pages: 3027-3041
- DOI
  10.1016/j.ymthe.2021.05.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07694, KAKENHI-PROJECT-20K20498
[Journal Article] On-admission SARS-CoV-2 RNAemia as a single potent predictive marker of critical condition development and mortality in COVID-192021
- Author(s)
  Miki Shoji、Sasaki Hiroaki、Horiuchi Hiroshi、Miyata Nobuyuki、Yoshimura Yukihiro、Miyazaki Kazuhito、Matsumura Takayuki、Takahashi Yoshimasa、Suzuki Tadaki、Matano Tetsuro、Kawana-Tachikawa Ai、Tachikawa Natsuo
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 7 Pages: e0254640-e0254640
- DOI
  10.1371/journal.pone.0254640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20498
[Journal Article] HIV感染症と免疫老化2021
- Author(s)
  Alitzel Anzurez, 立川 (川名)愛、俣野哲朗
- Journal Title
  
  日本臨床
  
  Volume: 79 Pages: 188-188
- Data Source
  KAKENHI-PROJECT-20K20498
[Journal Article] CD8+ T cell-based strong selective pressure on multiple simian immunodeficiency virus targets in macaques possessing a protective MHC class I haplotype2019
- Author(s)
  Hau Trang Thi Thu、Nakamura-Hoshi Midori、Kanno Yoshiaki、Nomura Takushi、Nishizawa Masako、Seki Sayuri、Ishii Hiroshi、Kawana-Tachikawa Ai、Hall William W.、Nguyen Thi Lan Anh、Matano Tetsuro、Yamamoto Hiroyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 512 Issue: 2 Pages: 213-217
- DOI
  10.1016/j.bbrc.2019.03.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07157, KAKENHI-PROJECT-18K15175, KAKENHI-PROJECT-17H02185, KAKENHI-PROJECT-19K16679, KAKENHI-PROJECT-18H02666
[Journal Article] Human Leukocyte Antigen-Associated HIV-1 CRF02_AG <i>gag</i> and <i>vif</i> Polymorphisms in Ghana2019
- Author(s)
  Adusei-Poku MA, Matsuoka S, Bonney EY, Abana CZ, Duker EO, Nii-Trebi NI, Ofori SB, Mizutani T, Ishizaka A, Shiino T, Kawana-Tachikawa A, Ishikawa K, Ampofo WK, Matano T
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 72 Issue: 6 Pages: 374-380
- DOI
  10.7883/yoken.JJID.2019.201
- NAID
  130007749423
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02185, KAKENHI-PROJECT-18H02666
[Journal Article] Characterization of In Vitro Expanded Virus-Specific T cells for Adoptive Immunotherapy against Virus Infection2018
- Author(s)
  Ono T, Fujita Y, Matano T, Takahashi S, Morio T, Kawana-Tachikawa A
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 71 Issue: 2 Pages: 122-128
- DOI
  10.7883/yoken.JJID.2017.500
- NAID
  130006517125
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04737, KAKENHI-PROJECT-17H02185
[Journal Article] Generation of multivirus-specific T cells by a single stimulation of peripheral blood mononuclear cells with a peptide mixture using serum-free medium2018
- Author(s)
  NISHIYAMA-FUJITA YURIKO、KAWANA-TACHIKAWA AI、ONO TOSHIAKI、TANAKA YUKIE、KATO TAKAFUMI、HESLOP HELEN E.、MORIO TOMOHIRO、TAKAHASHI SATOSHI
- Journal Title
  
  Cytotherapy
  
  Volume: 20 Issue: 9 Pages: 1182-1190
- DOI
  10.1016/j.jcyt.2018.05.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07292, KAKENHI-PROJECT-18K19507, KAKENHI-PROJECT-17H02185
[Journal Article] Alternative splicing regulator RBM20 in cardiomyopathy2018
- Author(s)
  Watanabe T, Kimura A, Kuroyanagi H
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 5 Issue: 2 Pages: 105-105
- DOI
  10.1016/j.micinf.2018.10.001
- NAID
  120007150215
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05296, KAKENHI-PROJECT-18H02666, KAKENHI-PROJECT-17H02185
[Journal Article] Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA.2018
- Author(s)
  Higaki K, Hirao M, Kawana-Tachikawa A, Iriguchi S, Kumagai A, Ueda N, Bo W, Kamibayashi S, Watanabe A, Nakauchi H, Suzuki K, Kaneko S.
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: 12 Pages: 723-804
- DOI
  10.1016/j.omtn.2018.07.017
- NAID
  120006649570
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0108, KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-17H02185, KAKENHI-PROJECT-18H02641, KAKENHI-PROJECT-18H02826
[Journal Article] Conserved Vδ1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by δ/αβ T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs2017
- Author(s)
  Shi Yi、Kawana-Tachikawa Ai、Gao Feng、Qi Jianxun、Liu Chuansheng、Gao Jia、Cheng Hao、Ueno Takamasa、Iwamoto Aikichi、Gao George F.
- Journal Title
  
  Journal of Virology
  
  Volume: 91 Issue: 17
- DOI
  10.1128/jvi.00725-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02185
[Journal Article] Homeostatically Maintained Resting Naive CD4+ T Cells Resist Latent HIV Reactivation.2016
- Author(s)
  Tsunetsugu-Yokota Y, Kobayahi-Ishihara M, Wada Y, Terahara K, Takeyama H, Kawana-Tachikawa A, Tokunaga K, Yamagishi M, Martinez JP, Meyerhans A.
- Journal Title
  
  Front. Microbiol.
  
  Volume: 7 Pages: 1944-1944
- DOI
  10.3389/fmicb.2016.01944
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-15H06877, KAKENHI-PROJECT-26460500, KAKENHI-PROJECT-15K12694, KAKENHI-PROJECT-15K06907
[Journal Article] Short intracellular HIV-1 transcripts as biomarkers of residual immune activation in patients on antiretroviral therapy.2016
- Author(s)
  A. Ishizaka, H. Sato, H. Nakamura, M. Koga, T. Kikuchi, N. Hosoya, T. Koibuchi, A. Nomoto, A. Kawana-Tachikawa and T. Mizutani
- Journal Title
  
  Journal of Virology
  
  Volume: 未確定 Issue: 12 Pages: 5665-76
- DOI
  10.1128/jvi.03158-15
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19117, KAKENHI-PROJECT-15K12694
[Journal Article] Short intracellular HIV-1 transcripts as biomarkers of residual immune activation in patients on antiretroviral therapy.2016
- Author(s)
  Ishizaka A, Sato H, Nakamura H, Kota M, Kikuchi T, Hosoya N, Koibuchi T, Kawana-Tachikawa A, Mizutani T.
- Journal Title
  
  Journal of Virology
  
  Volume: 90
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293226
[Journal Article] Rapid HIV-1 disease progression in individuals infected with a virus adapted to its host population.2016
- Author(s)
  Katoh J, Kawana-Tachikawa A, Shimizu A, Zhu D, Han C, Nakamura H, Koga M, Kikuchi T, Adachi E, Koibuchi T, Gao GF, Brumme ZL, Iwamoto A.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 3 Pages: e0150397-e0150397
- DOI
  10.1371/journal.pone.0150397
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12694, KAKENHI-PROJECT-25293226, KAKENHI-PROJECT-15K19584
[Journal Article] A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy.2015
- Author(s)
  Ando M, Nishimura T, Yamazaki S, Yamaguchi T, Kawana-Tachikawa A, Hayama T, Nakauchi Y, Ando J, Ota Y, Takahashi S, Nishimura K, Ohtaka M, Nakanishi M, Miles JJ, Burrows SR, Brenner MK, Nakauchi H
- Journal Title
  
  Stem Cell Reports
  
  Volume: 5(4) Pages: 597-608
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293357
[Journal Article] Epigenetic repression of interleukin-2 expression in senescent CD4+ T cells during chronic human immunodeficiency virus type-1 infection.2015
- Author(s)
  Nakayama-Hosoya K, Ishida T, Youngblood B, Nakamura H, Hosoya N, Koga M, Koibuchi T, Iwamoto A, Kawana-Tachikawa A.
- Journal Title
  
  Journal of Infectious Diseases
  
  Volume: 2112 Issue: 1 Pages: 28-39
- DOI
  10.1093/infdis/jiu376
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293226, KAKENHI-PROJECT-26293357, KAKENHI-PROJECT-26860300
[Journal Article] A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy.2015
- Author(s)
  Ando M, Nishimura T, Yamazaki S, Yamaguchi T, Kawana-Tachikawa A, Hayama T, Nakauchi Y, Ando J, Ota Y, Takahashi S, Nishimura K, Ohtaka M, Nakanishi M, Miles JJ, Burrows SR, Brenner MK, Nakauchi H.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 5(4) Issue: 4 Pages: 597-608
- DOI
  10.1016/j.stemcr.2015.07.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460358, KAKENHI-PROJECT-15J40133, KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-26870074, KAKENHI-PROJECT-25293226, KAKENHI-PROJECT-25713037
[Journal Article] Association between a naturally arising polymorphism within a functional region of HIV-1 Nef and disease progression in chronic HIV-1 infection.2015
- Author(s)
  Merlbe SC, Hasan Z, Mahiti M, Toyoda M, Mori M, Gatanaga H, Kikuchi T, Miura T, Kawana-Tachikawa A, Iwamoto A, Oka S, Ueno T.
- Journal Title
  
  Archives of Virology
  
  Volume: 160 Pages: 2033-2041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293226
[Journal Article] Association between a naturally arising polymorphism within a functional region of HIV-1 Nef and disease progression in chronic HIV-1 infection.2015
- Author(s)
  Merlbe SC, Hasan Z, Mahiti M, Toyoda M, Mori M, Gatanaga H, Kikuchi T, Miura T, Kawana-Tachikawa A, Iwamoto A, Oka S, Ueno T.
- Journal Title
  
  Archives of Virology
  
  Volume: 160 Pages: 2033-2041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12694
[Journal Article] Anti-APOBEC3G Activity of HIV-1 Vif Protein Is Attenuated in Elite Controllers.2015
- Author(s)
  Kikuchi T, Iwabu Y, Tada T, Kawana-Tachikawa A, Koga M, Hosoya N, Nomura S, Brumme ZL, Jessen H, Pereyra F, Trocha A, Walker BD, Iwamoto A, Tokunaga K, Miura T.
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 9 Pages: 4992-5001
- DOI
  10.1128/jvi.03464-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860300, KAKENHI-PROJECT-15K12694, KAKENHI-PROJECT-25293226
[Journal Article] Switching and emergence of CTL epitopes in HIV-1 infection2014
- Author(s)
  Han, C., Kawana-Tachikawa, A., Shimizu, A., Zhu D., Nakamura, H., Adachi, E., Kikuchi, T., Koga, M., Koibuchi, T., Gao, G.F., Sato, Y., Yamagata, A., Martin, E., Fukai, S., Brumme, Z.L.,Iwamoto, A.
- Journal Title
  
  Retrovirolgy
  
  Volume: 11 Issue: 1 Pages: 38-38
- DOI
  10.1186/1742-4690-11-38
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22121003, KAKENHI-PROJECT-24570126, KAKENHI-PROJECT-25293226
[Journal Article] Effect of Maraviroc Intensification on HIV-1-Specific T Cell Immunity in Recently HIV-1-Infected Individuals.2014
- Author(s)
  Kawana-Tachikawa A, Llibre JM, Bravo I, Escrig R, Mothe B, Puig J, Puertas MC, Martinez-Picado J, Blanco J, Manzardo C, Miro JM, Iwamoto A, Pozniak AL, Gatell JM, Clotet B, Brander C; MARAVIBOOST investigators.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e87334-e87334
- DOI
  10.1371/journal.pone.0087334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293226
[Journal Article] Development and Customization of a Color-Coded Microbeads-Based Assay for Drug Resistance in HIV-1 Reverse Transcriptase.2014
- Author(s)
  Gu L, Kawana-Tachikawa A, Shiino T, Nakamura H, Koga M, Kikuchi T, Adachi E, Koibuchi T, Ishida T, Gao GF, Matsushita M, Sugiura W, Iwamoto A, Hosoya N.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 10 Pages: e109823-e109823
- DOI
  10.1371/journal.pone.0109823
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293226, KAKENHI-PROJECT-26293357, KAKENHI-PROJECT-26860300
[Journal Article] Switching and emergence of CTL epitopes in HIV-1 infection.2014
- Author(s)
  Han C, Kawana-Tachikawa A, Shimizu A, Zhu D, Nakamura H, Adachi E, Kikuchi T, Koga M, Koibuchi T, Gao GF, Sat Y, Yamagata A, Martin E, Fukai S, Brumme ZL, Iwamoto A
- Journal Title
  
  Retrovirology.
  
  Volume: 11 Pages: 38-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293357
[Journal Article] Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection2013
- Author(s)
  Shimizu, A., Kawana-Tachikawa. A., Yamagata, A., Han, C., Zhu, D., Sato, Y., Nakamura, H., Koibuchi, T., Carlson, J., Martin, E., Brumme, C.J., Shi, Y., Gao, G.F., Brumme, Z.L., Fukai, S., Iwamoto, A.
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 3097-3097
- DOI
  10.1038/srep03097
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22121003, KAKENHI-PROJECT-24570126, KAKENHI-PROJECT-24687012, KAKENHI-PUBLICLY-25112505, KAKENHI-PUBLICLY-25117711, KAKENHI-PROJECT-25293226
[Journal Article] Significant Reductions in Gag-Protease-Mediated HIV-1 Replication Capacity during the Course of the Epidemic in Japan2013
- Author(s)
  Nomura, S., N. Hosoya, Z. L. Brumme, M. A. Brockman, T. Kikuchi, M. Koga, H. Nakamura, T. Koibuchi, T. Fujii, J. M. Carlson, D. Heckerman, A. Kawana-Tachikawa, A. Iwamoto, and T. Miura.
- Journal Title
  
  J Virol
  
  Volume: 87 Issue: 3 Pages: 1465-76
- DOI
  10.1128/jvi.02122-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390203, KAKENHI-PROJECT-22590412, KAKENHI-PROJECT-24790437
[Journal Article] Generation of rejuvenated antigen-specific T cells by pluripotency reprogramming and redifferentiation2013
- Author(s)
  Nishimura T, Kaneko S, Kawana-Tachikawa A, Tajima Y, Gotoh H, Zhu D, Nakayama K, Iriguchi S, Uemura Y, Shimizu T, Takayama N, Yamada D, Nishimura K, Ohtaka M, Watanabe N, Takahashi S, Iwamoto A, Koseki H, Nakanishi M, Eto K, Nakauchi H.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 114-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Journal Article] Development of a rapid cell-fusion-based phenotypic HIV-1 tropism assay.2013
- Author(s)
  Teeranaipong P, Hosoya N, Kawana-Tachikawa A, Fujii T, Koibuchi T, Nakamura H, Koga M, Kondo N, Gao GF, Hoshino H, Matsuda Z, Iwamoto A.
- Journal Title
  
  Journal of the International AIDS Society.
  
  Volume: 16 Issue: 1 Pages: 18723-18732
- DOI
  10.7448/ias.16.1.18723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790437, KAKENHI-PROJECT-25293226
[Journal Article] Improved neutralizing antibody response in the second season after a single dose of pandemic (H1N1) 2009 influenza vaccine in HIV-1-positive adults2012
- Author(s)
  Kikuchi T, Iwatsuki-Horimoto K, Adachi E, Koga M, Nakamura H, Hosoya N, Kawana-Tachikawa A, Koibuchi T, Miura T, Fujii T, Kawaoka Y, Iwamoto A.
- Journal Title
  
  Vaccine
  
  Volume: 30 Issue: 26 Pages: 3819-23
- DOI
  10.1016/j.vaccine.2012.03.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412, KAKENHI-PROJECT-24590786, KAKENHI-PROJECT-24790437
[Journal Article] Imbalanced production of cytokines by T cells associates with the activation/exhaustion status of memory T cells in chronic HIV Type 1 infection2012
- Author(s)
  Nakayama K, Nakamura H, Koga M, Koibuchi T, Fujii T, Miura T, Iwamoto A, Kawana-Tachikawa A.
- Journal Title
  
  AIDS Res Hum Retroviruses
  
  Volume: 28 Issue: 7 Pages: 702-14
- DOI
  10.1089/aid.2011.0073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Journal Article] Long-term successful control of super-multidrug-resistand human immunodeficiency virus type 1 infection by a novel combination therapy of raltegravir, etravirine, and boosted-darunavir2011
- Author(s)
  Nakamura H, Miyazaki N, Hosoya N, Koga M, Odawara T, Kikuchi T, Koibuchi T, Kawana-Tachikawa A, Fujii T, Miura T, Iwamoto A
- Journal Title
  
  Journal of Infection Chemotherapy and chemotherapy
  
  Volume: 17 Pages: 105-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Journal Article] Long-term successful control of super-multidrug-resistant human immunodeficiency virus type 1 infection by a novel combination therapy of raltegravir,etravirine, and boosted-darunavir2011
- Author(s)
  Nakamura H, Miyazaki N, Hosoya N, Koga M, Odawara T, Kikuchi T, Koibuchi T, Kawana-Tachikawa A, Fujii T, Miura T, Iwamoto A.
- Journal Title
  
  J Infect Chemother
  
  Volume: 17 Pages: 105-10
- NAID
  10027816880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Journal Article] Long-term successful control of supermultidrug-resistant human immunodeficiency virus type 1 infection by a novel combination therapy of raltegravir, etravirine, and boosted-darunavir.2011
- Author(s)
  Nakamura, H., Miyazaki, N., Hosoya, N., Koga, M., Odawara, T., Kikuchi, T., Koibuchi, T., Kawana-Tachikawa, A., Fujii, T., Miura, T., Iwamoto, A.
- Journal Title
  
  J Infect Chemother
  
  Volume: 17 Pages: 105-110
- NAID
  10027816880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390203
[Journal Article] HIV-1 tropism2010
- Author(s)
  Iwamoto A, Hosoya N, Kawana-TachikawaA.
- Journal Title
  
  Protein Cell
  
  Volume: 1 Issue: 6 Pages: 510-3
- DOI
  10.1007/s13238-010-0066-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Journal Article] Changes in impact of HLA class I allele expression on HIV-1 plasma virus loads at a population level over time2010
- Author(s)
  Koga M, Kawana-Tachikawa A, Heckerman D, Odawara T, Nakamura H, Koibuhi T, Fujii T, Miura T, Iwamoto A.
- Journal Title
  
  MicrobiolImmunol
  
  Volume: 54 Issue: 4 Pages: 196-205
- DOI
  10.1111/j.1348-0421.2010.00206.x
- NAID
  10029544438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Journal Article] Novel immunodominant peptide presentation strategy: a featured HLA-A*2402 restricted CTL-epitope stabilized by intra-chain hudrogen-bonds from SARS-CoV nucleocapsid protein2010
- Author(s)
  Liu J, Wu P, Gao F, Qi J, Kawana-Tachikawa A, Xie J, Vavricka CJ, Iwamoto A, Li T, Gao GF.
- Journal Title
  
  J Virol
  
  Volume: 84 Issue: 22 Pages: 11849-57
- DOI
  10.1128/jvi.01464-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Journal Article] Highly restricted T-cell receptor repertoire in the CD8+ T-cell response against an HIV-1 epitope with a stereotypic amino acid substitution2009
- Author(s)
  Miyazaki, E., Kawana-Tachikawa, A., Tomizawa, M., Nunoya J-I., Odawara T., Fujii, T., Shi, Y., Gao G.F., Iwamoto, A.
- Journal Title
  
  AIDS 23
  
  Pages: 651-660
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Activation of HIV-1 Gag-specific CD8+ T cells by yeast-derived VLP-pulsed dendritic cells is influenced by the level of mannose on the VLP antigen2009
- Author(s)
  Mizukoshi, F., Yamamoto, T., Mitsuki Y.Y., Terahara, K., Kawana-Tachikawa, A., Kobayashi, K., Iwamoto A., Morikawa, Y., Tsunetsugu-Yokota, Y.
- Journal Title
  
  Microbes Infection 11
  
  Pages: 191-19
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Comparison between Sendai virus and Adenovirus vectors in induction of HIV-1 genes into human dendritic cells2008
- Author(s)
  Hosoya, N., Miura, T., Kawana-Tachikawa, A., Shioda, T., Odawara, T.,Nakamura, T., Kitamura, Y., Kano, M., Kato, A., Hironaka, T., Hasegawa, M.,Nagai, Y., Iwamoto, A.
- Journal Title
  
  J. Medical Virology 80
  
  Pages: 373-382
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Generation of recombinant monoclonal antibodies against an immunodominant HLA-A*2402-restricted HIV-1 CTL epitope
- Author(s)
  Nunoya, J-I., Nakashima, T., Kawana-Tachikawa, A., Kiyotani, K., Ito, Y., Sugimura, K., Iwamoto, A.
- Journal Title
  
  AIDS Research and Human Retroviruses (In press)
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Imbalanced production of cyotokines by T cells associates with the activation/exhaust ion status of memory T cells in chronic HIV type 1 infection
- Author(s)
  Nakayama K, Nakamura H, Koga M, Koibuchi T, Fujii T, Miura T, Iwamoto A, Kawana-Tachikawa A
- Journal Title
  
  AIDS Research and Human Retroviruses
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Analysis of S-specific T cell responses after SARS-CoV-2 mRNA vaccines in people living with HIV.2023
- Author(s)
  Ai Kawana-Tachikawa, Thi Thu Thao Dang, Alitzel Anzurez, Kaori Hosoya-Nakayama, Aki Tanabe, Yukihiro Yoshimura, Natsuo Tachikawa, Tetsuro Matano
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] HIV長期感染者におけるSARS-CoV-2 mRNAワクチン誘導性S抗原特異的T細胞応答の解析2023
- Author(s)
  Dang Thi Thu Thao, 細谷(中山)香、Alitzel Anzurez、田部亜希、吉村幸浩、立川夏夫、俣野哲朗、立川（川名）愛
- Organizer
  第37回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] Inferior durability of SARS-CoV-2-specific T cells induced by mRNA vaccination in people living with HIV2023
- Author(s)
  Ai Kawana-Tachikawa, Thi Thu Thao Dang, Tetsuro Matano.
- Organizer
  FASEB Science Research Conferences, The HIV reservoirs and immune control conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] HIVリザーバーと免疫システム2023
- Author(s)
  立川（川名）愛
- Organizer
  第37回日本エイズ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] T cell immunology in viral infection based on TCR repertoire analysis2022
- Author(s)
  Ai Kawana-Tachikawa
- Organizer
  the 2nd France-Japan symposium on HIV/AIDS and Infectionus Diseases Basic Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] Identification of SARS-CoV-2-specufic T cell targets in COVID-19 convalescent individuals2022
- Author(s)
  25.Dang Thi Thu Thao、Alitzel Anzurez、細谷（中山）香、山下和男、俣野哲朗、立川(川名)愛
- Organizer
  第36回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] HIV感染者でのSARS-CoV-2特異的T細胞応答の解析2022
- Author(s)
  26.Alitzel Anzurez、細谷(中山)香、Thi Thu Thao Dang、古賀道子、立川夏夫、俣野哲朗、立川(川名)愛
- Organizer
  第36回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] Maintenance of T cell responses against SARS-CoV-2 in Japanese convalescent individuals from COVID-192021
- Author(s)
  Thi Tu Thao Dang、Alitzel Anzurez、細谷（中山）香、三木祥治、Nicola Sax、山下和男、俣野哲朗、立川（川名）愛
- Organizer
  第35回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20498
[Presentation] Development of T-cell based immunotherapy for HIV cure2020
- Author(s)
  Ai Kawana-Tachikawa
- Organizer
  United States-Japan Cooperative Medical Sciences Program 22nd International Conference on Emerging Infectious Diseases in the Pacific Rim, AIDS Panel
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02185
[Presentation] HIV感染でのT細胞老化とDNAメチル化による発現制御2019
- Author(s)
  立川(川名)愛、細谷(中山)香、関真秀、堀内映実、古賀道子、四柳宏、吉村幸浩、立川夏夫、鈴木穣、俣野哲朗
- Organizer
  第33回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-17H02185
[Presentation] T cell aging at molecular level during HIV infection2019
- Author(s)
  Ai Kawana-Tachikawa
- Organizer
  3.France-Japan Symposium on HIV and hepatitis basic research.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02185
[Presentation] T cell senescence in chronic HIV infection2019
- Author(s)
  Ai Kawana-Tachikawa
- Organizer
  3rd Japan-Taiwan Joint Symposium on HIV/AIDS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02185
[Presentation] HIV感染におけるメモリーCD4+T細胞のメチローム解析.2018
- Author(s)
  立川(川名)愛、細谷(中山)香、関真秀、堀内映実、佐藤秀憲、古賀道子、鯉渕智彦、四柳宏、吉村幸浩、立川夏夫、鈴木穣、俣野哲朗
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-17H02185
[Presentation] NGS法HLA解析のHIV及び関連疾患研究への応用2017
- Author(s)
  立川(川名) 愛
- Organizer
  1.第26回日本組織適合性学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02185
[Presentation] iPS細胞技術を用いて作製したHIV特異的細胞傷害性Tリンパ球の解析2016
- Author(s)
  立川(川名)愛、河合洋平、金子新
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] HIV感染者における胃炎と腸管遊走性CD4陽性T細胞の検討.2016
- Author(s)
  23.佐藤秀憲、大田泰徳、松原康朗、菊地正、古賀道子、鯉渕智彦、俣野哲朗、立川　愛、安達英輔
- Organizer
  第30回日本エイズ学会学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15K12694
[Presentation] iPS細胞技術を用いて作製したHIV特異的細胞傷害性Tリンパ球の解析.2016
- Author(s)
  立川(川名)愛、河合洋平、金子新
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K12694
[Presentation] 多ウイルス特異的T細胞療法における標的部位の同定法の確立2015
- Author(s)
  立川（川名）愛、小野敏明、藤田由利子、田中ゆきえ、高橋聡、森尾友宏
- Organizer
  第７回血液疾患免疫療法研究会
- Place of Presentation
  東京
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] 多ウイルス特異的T細胞療法における標的部位の同定(エピトープマッピング)法の確立2015
- Author(s)
  立川(川名)愛、小野敏明、藤田由利子、田中ゆきえ、高橋聡、森尾友宏.
- Organizer
  第７回血液疾患免疫療法研究会
- Place of Presentation
  東京大学伊藤国際学術研究センター内伊藤謝恩ホール（東京都文京区）
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] 実臨床応用に向けたウイルス特異的T細胞療法の開発2014
- Author(s)
  藤田由利子、小野敏明、落合央、立川愛、Leen AM, Heslop HE, 森尾友宏、高橋聡
- Organizer
  第6回血液疾患免疫療法研究会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] Low IL-2 expression by epigenetic modification is associated with immunosenescence in HIV non-controllers.2014
- Author(s)
  Kaori Nakayama-Hosoya, Takaomi Ishida, Noriaki Hosoya, Hitomi Nakamura, Michiko Koga, Tomohiko Koibuchi, Aikichi Iwamoto, Ai Kawana-Tachikawa.
- Organizer
  Keystone symposia, HIV Pathogenesis – Virus vs Host.
- Place of Presentation
  Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] 中国HIV-1感染者の未治療検体における副受容体指向性の検査2014
- Author(s)
  Gu L, Han Y, Guan S, Yang F, Zhu T, 合田仁、Cao Y, 立川(川名)愛、細谷紀彰、Gao FG, 岩本愛吉、Li T, 石田尚臣
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] The essential role of epigenetic regulation for CD4+ T cell dysfunction during chronic HIV-1 infection.2013
- Author(s)
  Kaori Nakayama-Hosoya, Takaomi Ishida, Noriaki Hosoya, Hitomi Nakamura, Michiko Koga, Tomohiko Koibuchi, Aikichi Iwamoto, Ai Kawana-Tachikawa.
- Organizer
  AIDS Vaccine 2013 Conference
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] 重複するCTLエピトープ部位に生じた１アミノ酸変異によるエピトープの消滅と出現2013
- Author(s)
  立川（川名）愛、韓忠勇、清水晃尚、細谷紀彰、中村仁美、古賀道子、鯉渕智彦、岩本愛吉
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] Prolonged preservation of HIV-specific cellular immunity in recently HIV-infected individuals receiving Maraviroc intensified HAART.2013
- Author(s)
  Kawana-Tachikawa A, Llibre JM, Bravo I, Escrig R, Mothe B, Miro JM, Gatell JM, Iwamoto A, Clotet B, Brander C.
- Organizer
  20th conference on retroviruses and opportunistic infections
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Mechanisms underlying disruption of T cell immunity during chronic HIV-1 infection2013
- Author(s)
  Kawana-Tachikawa A
- Organizer
  The 2nd joint global COE sympoisum of the IMSUT & RCAST global COE, The university of Tokyo and Chiba university global COE "Current and future trends in genome-based immunity, infection and cancer"
- Place of Presentation
  東京ステーションコンファレンス（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Impact of an amino acid change within overlapping CTL epiotpes in HIV-1 infection. Keystone symposia2013
- Author(s)
  Han Chungyong, Shimizu A, Zhu D, Kawana-Tachikawa A, Iwamoto A.
- Organizer
  HIV Vaccines
- Place of Presentation
  Keystone Colorado, USA
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Mechanisms underlying disruption of T cell immunity during chronic HIV-1 infection. The 2nd Joint Global COE Symposium of the IMSUT & RCAST Global COE, The University of Tokyo and Chiba University Global COE "Current and Future Trends in Genome-based Immunity2013
- Author(s)
  Kawana-Tachikawa A.
- Organizer
  Infection and Cancer
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] HIV感染者におけるパンデミック2009(H1N1)インフルエンザワクチンの初回接種前後と2年目の接種前後の中和抗体価の推移.2012
- Author(s)
  菊地正、岩附研子、安達英輔、古賀道子、中村仁美、立川愛、鯉渕智彦、藤井毅、河岡義裕、岩本愛吉.
- Organizer
  第12回東京大学生命科学シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] HIV-1elitecontrollerにおけるHIV-1Vifの抗APOBEC3G活性の低下2012
- Author(s)
  菊地正、岩部幸枝、立川(川名)愛、古賀道子、野村滋、細谷紀彰、BrummeZL,HeikoJ,KelleherAD,MarkowitzM,PereyraF,TrochaA,WalkerBD,岩本愛吉、徳永研三、三浦聡之.
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Anti-APOBEC3G activity of HIV-1 Vifprotein from elite controllers is attenuated compared to those from untreated chronic progressors of those from individuals with acute infection.2012
- Author(s)
  Kikuchi T, Iwabu Y, Kawana-Tachikawa A, Koga M, Nomura S, Hosoya N, Brumme ZL, Heiko J, Kelleher AD, Markowitz M, Pereyra F, Trocha A, Walker BD, Iwamoto A, Tokunaga K, Miura T.
- Organizer
  XIX International AIDS Conference
- Place of Presentation
  Washington DC, USA.
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Development of a HIV-1 phenotypic tropism assay using dual split protein (DSP)-mediated membrane fusion detection system".2012
- Author(s)
  Hosoya N. Teeranaipong P,Kawana-Tachikawa A, Kondo N, Hoshino H, Matsuda Z, Iwamoto A.
- Organizer
  1st Asian Conference on Hepatitis B and C, HIV and Influenza
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Replication capacities of chimeric NL4-3 encoding gag-protease from modern HIV-1 isolates are significantly reduced compared to those derived from isolates in the early days of epidemic in Japan2011
- Author(s)
  S. Nomura, N. Hosoya, T. Kikuchi, M. Koga, H. Nakamura, T. Koibuchi, T. Fujii, A. Kawana-Tachikawa, A. Iwamoto, T. Miura
- Organizer
  6th IAS Conference on HIVPathogenesis, Treatment and Prevention
- Place of Presentation
  ローマ, イタリア
- Data Source
  KAKENHI-PROJECT-22390203
[Presentation] Treatment and Prevention2011
- Author(s)
  S. Nomura, N. Hosoya, T. Kikuchi, M. Koga, H.Nakamura, T. Koibuchi, T. Fujii, A.Kawana-Tachikawa, A. Iwamoto, T. Miura
- Organizer
  Replication capacities of chimeric NL4-3 encoding gag-protease from modern HIV-1 isolates are significantly reduced compared to those derived from isolates in the early days of epidemic in Japan. 6th IAS Conference on HIVPathogenesis
- Place of Presentation
  ローマ, イタリア
- Data Source
  KAKENHI-PROJECT-22390203
[Presentation] 慢性感染症としてのHIV感染症の免疫学「HIV感染慢性期におけるT細胞の免疫病態」2011
- Author(s)
  立川(川名)愛
- Organizer
  第25回に本エイズ学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Replication capacities of chimeric NL4-3 encoding gag-protease from modern HIV-1 isolates are significantly reduced compared to those derived from isolates in the early days of epidemic in Japan2011
- Author(s)
  Nomura S, Hosoya N, Kikuchi T, Koga M, Nakamura H, Koibuchi T, Fujii T, Kawana-Tachikawa A, Iwamoto A, Miura T
- Organizer
  6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
- Place of Presentation
  Rome, Italy
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] HIV-1サブタイプ未同定の検体を用いた配列特異的オリゴプローブによる薬剤耐性変異の検出.2011
- Author(s)
  谷麗君、細谷紀彰、立川(川名)愛、中村仁美、古賀道子、松下正毅、BiyanLu、三浦聡之、岩本愛吉.
- Organizer
  第25回日本エイズ学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Replication capacities of chimeric NL4-3 encoding gag-protease from modern HIV-1 isolates are significantly reduced compared to those derived from isolates in the early days of epidemic in Japan2011
- Author(s)
  Nomura S, Hosoya N, Kikuchi T, Koga M, Nakamura H, Koibuchi T, Fujii T, Kawana-Tachikawa A, Iwamoto A, Miura T.
- Organizer
  6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
- Place of Presentation
  Rome Italy
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] 無症候慢性HIV-1陽性者由来gag-proteaseを発現するキメラNL4-3ウイルス複製能の患者初診年による変化.2011
- Author(s)
  野村滋,菊地正,細谷紀彰,古賀道子,中村仁美,鯉渕智彦,藤井毅,立川愛,岩本愛吉,三浦聡之
- Organizer
  第25回日本エイズ学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] HIV感染慢性期におけるT細胞の免疫病態2011
- Author(s)
  立川(川名)愛
- Organizer
  第25回日本エイズ学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Induction and maintenance of neutralizing antibodies after single dose of non-adjuvanted split 2009 pandemic H1N1 influenza A vaccine in HIV-1 positive population.2011
- Author(s)
  Kikuchi T, Iwatsuki-Horimoto K, Adachi E, Imai K, Shimizu S, Miyazaki N, Koga M, Nakamura H, Kawana-Tachikawa A, Koibuchi T, Miura T, Fujii T, Kawaoka Y, Iwamoto A.
- Organizer
  6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
- Place of Presentation
  Rome Italy
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Development of a PCR-SSOP-Liminex Assay for HIV-1 Drug Resistance. Session IV: Virology, Novel Therapies, and New Technologies.2010
- Author(s)
  Gu L, Kawana-Tachikawa A, Shiino T, Hosoya N, Nunoya J, Koibuchi T, Fujii T, Miura T, Matsushita M, Sugiura W, and Iwamoto A.
- Organizer
  24th Joint Meeting of the AIDS Panels, United States-Japan Cooperative Medical Science Program. HIV Resistance
- Place of Presentation
  Asia. Grand Copthorne Hotel, Singapore
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] T ell activation and exhaustion associates with skewed cytokines/chemokines production in chronic HIV-1 infection.2010
- Author(s)
  Nakayama K, Kawana-Tachikawa A, Nakamura H, Miura T, Fujii T, Koibuchi T, Iwamoto A.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] HIV-1 viral burden has an impact on Th1- and Th17-related cytokines/chemokines production of T cells.2010
- Author(s)
  Nakayama K, Kawana-Tachikawa A, Nakamura H, Miura T, Fujii T, Koibuchi T, Iwamoto A.
- Organizer
  18th International AIDS Conference
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] HIV感染者における2009パンデミックインフルエンザワ(H1N1)ワクチン接種後の中和抗体価の推移2010
- Author(s)
  菊地正、堀本研子、藤井毅、安達英輔、今井健太郎、清水少一、古賀道子、中村仁美、鯉渕智彦、立川愛、三浦聡之、河岡義裕、岩本愛吉
- Organizer
  第24回日本エイズ学会学術集会
- Place of Presentation
  グランドプリンス高輪ザープリンスさくらタワー東京
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-22390203
[Presentation] Novel HIV-1 Phenotypic Tropism Assay without Psuedotyoed Virions. Session IV: Virology, Novel Therapies, and New Technologies.24th Joint Meeting of the AIDS Panels,United States-Japan Cooperative Medical Science Program2010
- Author(s)
  Teeranaipong P, Hosoya N, Kawana-Tachikawa A. Kondo N, Hoshino H, Matsuda Z, and Iwamoto A.
- Organizer
  HIV Resistance
- Place of Presentation
  Asia. Grand Copthorne Hotel, Sigapore
- Data Source
  KAKENHI-PROJECT-22590412
[Presentation] Contribution of Gag-specific CD8+ T cells to HIV control in a population lacking HLA-B57/272009
- Author(s)
  Kawana-Tachikawa, A
- Organizer
  Keystone Symposia : HIV Immunology, Infection to Immune Control
- Place of Presentation
  Keystone
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Contribution of Gag-speclfic CD8+ T cells to HIV control in a population lacking HLA-B57/27.2009
- Author(s)
  Kawana-Tachikawa, A.
- Organizer
  Keystone Symposia: HIV Immunobiology,Infection to Immune Control
- Place of Presentation
  Keystone(アメリカ合衆国)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Maintenance of Proliferative PD-1 low Memory CD8+ T cells Specific forEradicated Virus in HIV-1 Patients with High CD4 Count2008
- Author(s)
  Kawana-Tachikawa, A.
- Organizer
  15th Conference onRetroviruses and Oppertunistic Infections
- Place of Presentation
  Boston (USA)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Maintenance of Proliferative PD-1 low Memory CD8+ T cells Specific forEradicated Virus in HIV-1 Patients with High CD4 Count2008
- Author(s)
  Kawana-Tachikawa, A
- Organizer
  15th Conference onRetroviruses and Oppertunistic Infections
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Highly restricted T cell receptor repertoire against an immunodominant HIV-1CTL epitope with a stereotypic amino acid substitution2007
- Author(s)
  Kawana-Tachikawa, A
- Organizer
  4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
- Place of Presentation
  Sydney
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Highly restricted T cell receptor repertoire against an immunodominant HIV-1CTL epitope with a stereotypic amino acid substitution2007
- Author(s)
  Kawana-Tachikawa, A.
- Organizer
  4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
- Place of Presentation
  Sydney (Australia)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Proposal of new immune cell source for HIV-1 infection study based on iPSCs and evaluation of impact of viral replication in iPSCs-derived macrophage expressing shRNAs targeting HIV-1 promoter
- Author(s)
  Hirao M, Suzuki K, Kawana-Tachikawa A, Nakauchi H, Cooper DA, Kelleher AD, Kaneko S
- Organizer
  20th International AIDS Conference
- Place of Presentation
  オーストラリア・メルボルン
- Year and Date
  2014-07-20 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] HIV-1感染におけるCD4陽性T細胞のIL2遺伝子発現低下分子メカニズムの解明
- Author(s)
  細谷(中山)香、石田尚臣、中村仁美、細谷紀彰、古賀道子、鯉渕智彦、岩本愛吉、立川(川名)愛
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] 臨床応用に向けた多ウイルス特異的T細胞培養法の確立とその特性解析
- Author(s)
  小野敏明、藤田由利子、立川(川名)愛、高橋聡、森尾友宏
- Organizer
  第42回日本臨床免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] Proposal of new immune cell source for HIV-1 infection study based on iPSCs and evaluation of impact of viral replication in iPSCs-derived macrophage expressing shRNAs targeting HIV-1 promoter.
- Author(s)
  Hirao M, Suzuki K, Kawana-Tachikawa A, Nakauchi H, Cooper DA, Kelleher AD, Kaneko S.
- Organizer
  The 20th International AIDS Conference
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2014-07-20 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] Disruption of T cell immunity during chronic HIV-1 infection.
- Author(s)
  Kawana-Tachikawa A.
- Organizer
  The 21st East Asia Joint Symposium on Biomedical Research
- Place of Presentation
  韓国・ソウル
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] Disruption of T cell immunity during chronic HIV-1 infection.
- Author(s)
  Ai Kawana-Tachikawa
- Organizer
  The 21st East Asia Joint Symposium on Biomedical Research
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-07-17 – 2014-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] HIV-1残存感染細胞の活性と免疫活性化の相関
- Author(s)
  石坂彩、佐藤秀憲、立川(川名)愛、中村仁美、古賀道子、細谷紀彰、鯉渕智彦、野本明男、岩本愛吉、水谷壮利
- Organizer
  第62回日本ウイルス学会学術集会、
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] HIV感染症に対する免疫細胞療法の可能性
- Author(s)
  立川（川名）愛
- Organizer
  第５回造血器腫瘍免疫療法研究会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] 恒常的に培養維持されたCD4陽性T細胞へのHIV-1の感染とその転写制御機構の解明
- Author(s)
  和田倭、小林(石原)美栄、寺原和孝、池野翔太、徳永研三、立川(川名)愛、山岸誠、竹山春子、横田(恒次)恭子
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] HIV感染者のCD8陽性T細胞における補助刺激分子OX40の検討
- Author(s)
  佐藤秀憲、細谷(中山)香、菊地正、安達英輔、古賀道子、中村仁美、鯉渕智彦、岩本愛吉、立川(川名)愛
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] HIV感染者のCD8陽性T細胞における補助刺激分子OX40の検討
- Author(s)
  佐藤秀憲、細谷(中山)香、菊地正、安達英輔、古賀道子、中村仁美、鯉渕智彦、岩本愛吉、立川(川名)愛
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26293357
[Presentation] Interaction between virus and host immune response during chronic HIV-1 infection.
- Author(s)
  Ai Kawana-Tachikawa
- Organizer
  The 9th China-Japan Laboratory Workshop: Pathogenesis, Gene regulation, and signal transduction.
- Place of Presentation
  Beijing, China
- Invited
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] HIV-1感染におけるCD4陽性T細胞のIL2遺伝子発現低下分子メカニズムの解明．
- Author(s)
  細谷(中山)香、石田尚臣、中村仁美、細谷紀彰、古賀道子、鯉渕智彦、岩本愛吉、立川(川名)愛
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25293226
[Presentation] Effects of natural variability of an immunodominant Vpr region on immunuological footprints, clinical outcome and protein functions
- Author(s)
  Kamori D, 村上知行、Hasan Z, Meribe S, Carlson J, Siarot L, 三浦聡之、立川(川名)愛、岩本愛吉、潟永博之、岡慎一、間陽子、上野貴将
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26293357

1. MIURA Toshiyuki (00296576)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
2. ARIYOSHI Koya (30311400)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KAWANA Kei (60311627)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. KANEKO Shin (40361331)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. IWAMOTO Aikichi (10133076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. HOSOYA Noriaki (30568928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. KUKIMOTO Iwao (70291127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOIBUCHI Tomohiko (50313094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. SEO SACHIKO (60401121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TSUCHIHARA KATSUYA (00415514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山本浩之 (80574615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 塚崎邦弘 (40274659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山下和男 (20749246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 木口悠也 (40897500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SATO Hidenori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. TACHIKAWA Natsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. MORI YUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. CHIBA SHIGERU

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KANDA YOSHINOBU

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. AOTSUKA NOBUYUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SAKAIDA EMIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ONODA MASAHIRO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SATO Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. NARUSE Taeko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. YAMAGUCHI Tomoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. WATANABE Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 田中ゆきえ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 深井周也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
29. 山形敦史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 河合洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 山岸誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 石坂彩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 木村彰方

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tachikawa Ai 立川 愛

TACHIKAWA Ai 立川 愛

Research Projects

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Co-Researchers

Research for infection immunity against global viral infections with a new bioinformatic approachPrincipal Investigator

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感染症に対する免疫力評価系の構築Principal Investigator

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Study of Immune agingPrincipal Investigator

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Analysis of T cells in immunological agingPrincipal Investigator

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Identification of reactivation factors for human herpes viruses

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Basic research for development of immunotherapy for cervical cancer by using regenerative medicine (induced pluripotent stem cell: iPS cell)

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Development of immunotherapy for HIV curePrincipal Investigator

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Molecular Epidemiology of HPV and HBV in men who have sex with men in South East Asia

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Investigation of change in HIV-1 replication capacityover the epidemic

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Influence of HIV protein kinetics on anti-HIV effects in HIV-specific cellular immune responsePrincipal Investigator

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Analysis of HIV-specific cellular immune response and antigen presentation in HIV infection

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[Journal Article] Multimodal single-cell analyses of peripheral blood mononuclear cells of COVID-19 patients in Japan2023

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[Journal Article] Breadth and Durability of SARS-CoV-2-Specific T Cell Responses following Long-Term Recovery from COVID-192023

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Tachikawa Ai 立川愛

TACHIKAWA Ai 立川愛