Nakajima Hideaki 中嶋秀明

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NAKAJIMA Hideaki 中嶋秀明

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Researcher Number	10397276
Other IDs
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Affiliation (Current)	2025: 福井大学, 学術研究院医学系部門, 准教授
Affiliation (based on the past Project Information) *help	2025: 福井大学, 学術研究院医学系部門, 准教授 2023: 福井大学, 学術研究院医学系部門, 准教授 2016 – 2022: 福井大学, 学術研究院医学系部門, 講師 2008 – 2015: University of Fukui, 医学部, 助教 2007: University of Fukui, 医学部附属病院, 助教 2006: 福井大学, 医学部附属病院, 助手 2005: 福井大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 脊髄損傷 / 神経障害性疼痛 / 遺伝子治療 / 神経栄養因子 / ttwマウス / ミクログリア / PET/MRI / PK11195 / 脊髄症 / PET … More / ニューロイメージング / 脊髄障害性疼痛 / 細胞移植 / 骨髄間質細胞 / 神経再生 / 逆行性導入 / 脊椎脊髄病学 / 逆行性遺伝子導入 / アデノウィルスベクター / イムノアッセイ / プロテオミクス / 共培養 / バイオマーカー / 疾患活動性評価 / エクソソーム解析 / 脊柱靱帯骨化症 / M2 / M1 / キメラマウス / 活性化ミクログリア / 遺伝子解析 / 圧迫性脊髄症 / マクロファージ / マイクログリア / PK1195 / 抗IL-6受容体抗体 / 脊髄損傷後疼痛 / 急性脊髄損傷 / 骨 / 神経保護効果 / apoptosis抑制 / 遺伝子導入 / 軸索再生 / 神経保護 / アポトーシス / 神経幹細胞 / 脊髓損傷 / 分化制御 / 前角部運動神経細胞 / sternomastoid muscle / target organ / retrograde axonal transport / adenovirus vector / gene therapy / gene delivery / neurotrophic factor / spinal cord injury … More Except Principal Investigator 神経障害性疼痛 / マイクロアレイ / 脊髄損傷 / 後縦靭帯骨化症 / 免疫組織化学的染色 / 内軟骨骨化 / インディアンヘッジホッグ / OPLL / 脊髄障害性疼痛 / マクロファージ / メカニカルストレス / 遺伝子解析 / 脊柱靭帯骨化症 / ttw mouse / mesenchymal stem cell / mouse / spinal cord injury / Exosome / ttw/ttwマウス / 慢性疼痛 / 骨髄由来間葉系間質細胞 / 圧迫性頸髄症 / 自然発症圧迫性頚髄症モデル（ttw/ttw） / 骨髄由来間葉系間質細胞（BMSC） / 圧迫性頚髄症 / 生体イメージング / 経静投与 / 髄腔内投与 / 脂肪由来間葉系間質細胞 / microglia/macrophage / M2 / M1 / M1/M2 phenotype / 活性化ミクログリア / pltマウス / CCL21 / ミクログリア / 軟骨細胞 / 頚椎 / 異所性骨化 / Indian Hedgehog / Runx 2 / Sox 9 / 免疫組織化学的検討 / 後縦靱帯骨化症 / immunohistochemistry / Sox9 / ectopic ossification / Indian hedgehog / 慢性圧迫脊髄 / 脊髄血液関門 / 頚椎症性脊髄症 / MAPK / twyマウス / 脊髄慢性圧迫 / 靭帯培養細胞 / 骨化伸展 / 活性型ミクログリア / 画像解析 / 培養靭帯細胞 / リアルタイムRT-PCR / 黄色靭帯骨化症 / 組織学的検討 / マイクロビーズ法 / 転写因子 / 黄色靭帯 / 後縦靭帯 / 骨化前線 / 脊椎脊髄病学 Less

脊柱靭帯骨化由来エクソソーム抗膜タンパク抗体による疾患活動性評価と骨化進展抑制Principal Investigator
- Principal Investigator
  
  中嶋秀明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Fukui
Neuroprotective, regenerative, and pain-suppressing effects of mesenchymal stromal cell-derived exosomes for neural injury
- Principal Investigator
  
  渡邉修司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Fukui
膜タンパク陽性エクソソームによる脊柱靱帯骨化の疾患活動性評価法の開発と機能解析Principal Investigator
- Principal Investigator
  
  中嶋秀明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Fukui
脂肪由来間質細胞による脊髄損傷治療 -髄腔内投与後の組織分布と運動機能解析-
- Principal Investigator
  
  高橋藍
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Fukui
Therapeutic value of mesenchymal stromal cells on motility disturbance and neuropathic pain associated with cervical compressive myelopathy.
- Principal Investigator
  
  竹浦直人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Fukui
Assessments of neuron-glia linkage in spinal cord-related pain and clinical significance of neuroimaging (PK11195 PET/MRI)Principal Investigator
- Principal Investigator
  
  Nakajima Hideaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Fukui
Distribution of CCL21 and activated microglia in spinal cord-related pain
- Principal Investigator
  
  Hirai Takayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Fukui
The study of the effect of mechanical stress on the enchondral ossification signals in the ossification of the posterior longitudinal ligament
- Principal Investigator
  
  Sugita Daisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
The assessment of molecular/cellular pathophysiology and the development of neuroimaging for spinal cord-related painPrincipal Investigator
- Principal Investigator
  
  Nakajima Hideaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
Pathological of neuropathic pain with chronic progressive spinal cord compression.
- Principal Investigator
  
  Takeura Naoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
ヒト骨化黄色靭帯由来培養細胞を用いた骨化伸展制御因子の特定
- Principal Investigator
  
  馬場久敏
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
The evaluation of protein expression and cyclic tensile strain of human OPLL
- Principal Investigator
  
  Sugita Daisuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
The basic reaserch for the pathologic symptom to improve the survival rate of transplanted bone marrow stromal cells in the injured spinal cordPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Hideaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
The molecular biological analysis of spinal cord related pain and the assessment of spinal cord function using neuroimaging
- Principal Investigator
  
  UCHIDA Kenzo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
The effects and mechanism of bone marrow stromal cells for spinalcord injuryPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Hideaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
Whole transcriptome analysis for ossification of vertebral ligament using RNA interference and microbeads array
- Principal Investigator
  
  UCHIDA Kenzo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
The control of neural-glial spinal cells microenvironment after traumatic injury through transfection of neurotrophic factorPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Hideaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
Differentiation control of endogenous and exogenous neural stem cells using neurotrophic factors in spinal cord injury studyPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Hideaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui
脊髄損傷に対するアデノウイルスベクターを用いた逆行性神経栄養因子遺伝子導入の検討Principal Investigator
- Principal Investigator
  
  中嶋秀明
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Fukui

[Book] Neuroprotection and Regeneration of the Spinal Cord2014
- Author(s)
  K Uchida, H Nakajima, H Okazawa, H Kimura, A Yoshida, H Baba
- Total Pages
  419
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24390351
[Book] ペインクリニシャンのための新キーワード 1352014
- Author(s)
  中嶋秀明, 内田研造, 馬場久敏, 牛田享宏
- Total Pages
  342
- Publisher
  真興交易（株）医書出版部
- Data Source
  KAKENHI-PROJECT-24390351
[Book] Neuroprotection and Regeneration of the Spinal Cord2014
- Author(s)
  K Uchida, H Nakajima, T Hirai, Sally Roberts, William E B Johnson, H Baba
- Total Pages
  419
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24390351
[Book] Case Library Series　痛みの診療ベストプラクティス2014
- Author(s)
  中嶋秀明, 内田研造, 馬場久敏
- Total Pages
  159
- Publisher
  株式会社メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24390351
[Book] Neuroprotection and Regeneration of the Spinal Cord2014
- Author(s)
  H Nakajima, K Uchida, Alexander Guerrero, S Watanabe, D Sugita, N Takeura, A Yoshida, H Baba
- Total Pages
  419
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24390351
[Book] Neuroprotection and Regeneration of the Spinal Cord2014
- Author(s)
  Baba H, Okada S, Nakamura M, Kanno H, Watanabe M, Ogata T, Ozawa H, Nishida N, Uchida K, Takano M, Koda M, Kitamura K, Imagama S, Nakajima H, Alexander Rodriguez Guerrero, Katoh S, Tsuji O, Abematsu M, Kumagai G, Enomoto M, et al.
- Total Pages
  419
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26462234
[Book] OPLL : Ossification of the Posterior Longitudinal Ligament, 2^<nd> edition(K Yonenobu, ed)2006
- Author(s)
  Hisatoshi Baba, Kenzo Uchida, Hideaki Nakajima, Yasuo Kokubo, et al.
- Total Pages
  305
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17790997
[Journal Article] Symptom- based characteristics and treatment efficacy of neuropathic pain related to spinal disorders2021
- Author(s)
  Nakajima H, Watanabe S, Honjoh K, Kubota A, Takeura N, Matsumine A
- Journal Title
  
  J Orthop Sci
  
  Volume: in press Issue: 6 Pages: 1222-1227
- DOI
  10.1016/j.jos.2021.08.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09645, KAKENHI-PROJECT-23K24456
[Journal Article] Distribution and polarization of microglia and macrophages at injured sites and the lumbar enlargement after spinal cord injury2020
- Author(s)
  Nakajima Hideaki、Honjoh Kazuya、Watanabe Shuji、Kubota Arisa、Matsumine Akihiko
- Journal Title
  
  Neuroscience Letters
  
  Volume: 737 Pages: 135152-135152
- DOI
  10.1016/j.neulet.2020.135152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09645, KAKENHI-PROJECT-18K09059
[Journal Article] Expression Analysis of Susceptibility Genes for Ossification of the Posterior Longitudinal Ligament of the Cervical Spine in Human OPLL-related Tissues and a Spinal Hyperostotic Mouse (ttw/ttw)2020
- Author(s)
  Nakajima Hideaki、Watanabe Shuji、Honjoh Kazuya、Okawa Atsushi、Matsumoto Morio、Matsumine Akihiko
- Journal Title
  
  Spine
  
  Volume: 45 Issue: 22 Pages: 1460-1468
- DOI
  10.1097/brs.0000000000003648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09645, KAKENHI-PROJECT-19K18494
[Journal Article] Cyclic tensile strain facilitates ossification of the cervical posterior longitudinal ligament via increased Indian hedgehog signaling2020
- Author(s)
  Sugita D, Nakajima H, Kokubo Y, Takeura N, Yayama T, Matsumine A.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(1) Issue: 1 Pages: 7231-7231
- DOI
  10.1038/s41598-020-64304-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10928, KAKENHI-PROJECT-18K09027, KAKENHI-PROJECT-19K09645
[Journal Article] Role of macrophages and activated microglia in neuropathic pain associated with chronic progressive spinal cord compression2019
- Author(s)
  Takeura N, Nakajima H, Watanabe S, Honjoh K, Takahashi A, Matsumine A
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 15656-15656
- DOI
  10.1038/s41598-019-52234-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09645
[Journal Article] Relationship of Inflammatory Cytokines From M1-Type Microglia/Macrophages at the Injured Site and Lumbar Enlargement With Neuropathic Pain After Spinal Cord Injury in the CCL21 Knockout (plt) Mouse2019
- Author(s)
  Honjoh K, Nakajima H, Hirai T, Watanabe S, Matsumine A
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 13 Pages: 525-525
- DOI
  10.3389/fncel.2019.00525
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09059, KAKENHI-PROJECT-19K09645
[Journal Article] Comparison of Mesenchymal Stromal Cells Isolated from Murine Adipose Tissue and Bone Marrow in the Treatment of Spinal Cord Injury.2018
- Author(s)
  Takahashi A, Nakajima H, Uchida K, Takeura N, Honjoh K, Watanabe S, Kitade M, Kokubo Y, Johnson WEB, Matsumine A.
- Journal Title
  
  Cell Transplantation
  
  Volume: 27 Issue: 7 Pages: 39-47
- DOI
  10.1177/0963689718780309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10817, KAKENHI-PROJECT-16K20043
[Journal Article] 脊髄障害性疼痛；特集「日常診療と慢性疼痛の管理」2016
- Author(s)
  中嶋秀明
- Journal Title
  
  成人病と生活習慣病
  
  Volume: 46 Pages: 835-838
- Data Source
  KAKENHI-PROJECT-16K10817
[Journal Article] 迫性頚髄症モデル（twyマウス）を用いた脊髄障害性疼痛に関する基礎的研究2016
- Author(s)
  竹浦直人, 中嶋秀明, 髙橋　藍, 他
- Journal Title
  
  中部整災誌
  
  Volume: 59 Pages: 675-676
- Data Source
  KAKENHI-PROJECT-16K10817
[Journal Article] Early Transplantation of Mesenchymal Stem Cells after Spinal Cord Injury Relieves Pain Hypersensitivity Through Suppression of Pain‐ Related Signaling Cascades and Reduced Inflammatory Cell Recruitment2015
- Author(s)
  S Watanabe, K Uchida, H Nakajima, H Matsuo, D Sugita, A Yoshida, K Honjoh, Johnson WE, H Baba
- Journal Title
  
  Stem Cells
  
  Volume: in press Issue: 6 Pages: 1902-1914
- DOI
  10.1002/stem.2006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390351, KAKENHI-PROJECT-25462290
[Journal Article] 慢性圧迫脊髄における疼痛発現に関する基礎的研究―twy chimeric mouseを用いて―2014
- Author(s)
  竹浦直人, 内田研造, 中嶋秀明, 渡邉修司, 吉田藍, 馬場久敏
- Journal Title
  
  厚生労働科学研究費補助金難治性疾患等克服研究事業脊柱靭帯骨化症に関する調査研究平成25年度総括・分担研究報告書
  
  Volume: 2014 Pages: 47-50
- Data Source
  KAKENHI-PROJECT-24390351
[Journal Article] Prognostic value of changes in spinal cord signal intensity on magnetic resonance imaging in patients with cervical compressive myelopathy.2014
- Author(s)
  Uchida K, Nakajima H, Takeura N, Yayama T, Guerrero AR, Yoshida A, Sakamoto T, Honjoh K, Baba H.
- Journal Title
  
  Spine J
  
  Volume: 14 Pages: 1601-1610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462234
[Journal Article] FDG-PETによる脊髄機能評価2014
- Author(s)
  中嶋秀明, 内田研造, 馬場久敏
- Journal Title
  
  Bone Joint Nerve　特集「整形外科イメージングの進歩」
  
  Volume: 4(2) Pages: 223-229
- Open Access
- Data Source
  KAKENHI-PROJECT-24390351
[Journal Article] Gene therapy strategies for the treatment of spinal cord injury2014
- Author(s)
  K Uchida, H Nakajima, Alexander Guerrero, William EB Johnson, Wagih El Masri, H Baba
- Journal Title
  
  Ther Deliv
  
  Volume: 5(5) Issue: 5 Pages: 591-607
- DOI
  10.4155/tde.14.20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390351, KAKENHI-PROJECT-26462234
[Journal Article] Early transcutaneous electrical nerve stimulation reduces hyperalgesia and decreases activation of spinal glial cells in mice with neuropathic pain2014
- Author(s)
  H Matsuo, K Uchida, H Nakajima, Alexander Guerrero, S Watanabe, N Takeura, D Sugita, S Shimada, T Nakatsuka, H Baba
- Journal Title
  
  Pain
  
  Volume: 155(9) Issue: 9 Pages: 1888-1901
- DOI
  10.1016/j.pain.2014.06.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390351
[Journal Article] 慢性圧迫脊髄における疼痛発現に関する基礎的研究―twy chimeric mouseを用いて―2013
- Author(s)
  竹浦　直人, 内田　研造, 中嶋　秀明, 渡邉　修司, 吉田　藍, 馬場　久敏
- Journal Title
  
  厚生労働科学研究費補助金難治性疾患等克服研究事業脊柱靭帯骨化症に関する調査研究平成25年度総括・分担研究報告書
  
  Volume: H25 Pages: 47-50
- Data Source
  KAKENHI-PROJECT-24390351
[Journal Article] The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: Implications for human cervical compressive myelopathy2013
- Author(s)
  T.Hirai, K.Uchida, H.Nakajima, Alexander Guerrero, N.Takeura, S.Watanabe, D.Sugita, A.Yoshida, W.E.Johnson, H.Baba
- Journal Title
  
  PLoS One
  
  Volume: 8(5) Issue: 5 Pages: e64528-e64528
- DOI
  10.1371/journal.pone.0064528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390351
[Journal Article] 慢性脊髄圧迫モデル（twy/twy mouse）を用いた脊髄後角におけるMAPK pathway に関する免疫組織学的検討2013
- Author(s)
  竹浦　直人, 内田　研造, 中嶋　秀明, 平井　貴之, 渡邉　修司, 馬場　久敏
- Journal Title
  
  中部整災誌
  
  Volume: 56(5) Pages: 1117-1118
- NAID
  130004144147
- Data Source
  KAKENHI-PROJECT-24390351
[Journal Article] Blockade of interleukin 6 signaling improves the survival rate of transplanted bone marrow stromal cells and increases locomotor function in mice with spinal cord injury2013
- Author(s)
  Tan Ying, K.Uchida, H.Nakajima, Alexander Guerrero, S.Watanabe, T.Hirai, N.Takeura, Lui Shao-Yu, Johnson William E.B., H.Baba
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 72（10） Issue: 10 Pages: 980-993
- DOI
  10.1097/nen.0b013e3182a79de9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390351, KAKENHI-PROJECT-24791530
[Journal Article] Apoptosis of neurons and oligodendrocytes in the spinal cord of spinal hyperostotic mouse(twy/twy): possible pathomechanism of human cervical compressive myelopathy2012
- Author(s)
  Uchida K, Nakajima H, Watanabe S, Yayama T, Guerrero AR, Inukai T, Hirai T, Sugita D, Johnson WE, Baba H
- Journal Title
  
  Eur Spine J
  
  Volume: 21 Pages: 490-497
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21935678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury2012
- Author(s)
  Nakajima H, Uchida K, Guerrero AR, Watanabe S, Sugita D, Takeura N, Yoshida A, Long G, Wright KT, Johnson WE, Baba H
- Journal Title
  
  J Neurotrauma
  
  Volume: 29 Pages: 1614-1625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791631
[Journal Article] Ossification process involving the human thoracic ligamentum flavum : role of transcription factors.2012
- Author(s)
  Uchida K, Yayama T, Cai HX, Nakajima H, Sugita D, Guerrero AR, Kobayashi S, Yoshida A, Chen KB, Baba H
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 13
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21914169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Initiation and progression of ossification of the posterior longitudinal ligament of the cervical spine in the hereditary spinal hyperostotic mouse (twy/twy)2012
- Author(s)
  Uchida K, Yayama T, Sugita D, Nakajima H, Rodriguez Guerrero A, Watanabe S, Roberts S, Johnson WE, Baba H
- Journal Title
  
  Eur Spine J
  
  Volume: 21 Pages: 149-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice2012
- Author(s)
  Guerrero AR, Uchida K, Nakajima H, Watanabe S, Nakamura M, Johnson WE, Baba H
- Journal Title
  
  J Neuroinflammation
  
  Volume: 27(9) Pages: 40-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791631
[Journal Article] Initiation and progression of ossification of the posterior longitudinal ligament of the cervical spine in the hereditary spinal hyperostotic mouse(twy/twy)2012
- Author(s)
  Uchida K, Yayama T, Sugita D, Nakajima H, Rodriguez Guerrero A, Watanabe S, Roberts S, Johnson WE, Baba H
- Journal Title
  
  Eur Spine J
  
  Volume: 21 Pages: 149-155
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21850419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury.2012
- Author(s)
  Nakajima H
- Journal Title
  
  J Neurotrauma
  
  Volume: 29 Issue: 8 Pages: 1614-1625
- DOI
  10.1089/neu.2011.2109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791631, KAKENHI-PROJECT-24791530
[Journal Article] High-mobility Group Box-1 and Its Receptors Contribute to Proinflammatory Response in the Acute Phase of Spinal Cord Injury in Rats2011
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Hirai T, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Zhu P, Baba H
- Journal Title
  
  Spine
  
  Volume: 36 Pages: 2122-2129
- NAID
  10030901954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791631
[Journal Article] Tumor necrosis factor-αantagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury2011
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Hirai T, Watanabe S, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Baba H
- Journal Title
  
  Spine(Phila Pa 1976)
  
  Volume: 36 Pages: 1350-1358
- NAID
  10030716262
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21224756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] High-mobility group box-1 and its receptors contribute to proinflammatory response in the acute phase of spinal cord injury in rats.2011
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Hirai T, Rodriguez Guerrero A, Kobayashi S, Ma WY, Liu SY, Zhu P, Baba H.
- Journal Title
  
  Spine (Phila Pa 1976)
  
  Volume: 36 Pages: 2122-2129
- NAID
  10030901954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791631
[Journal Article] Tumor necrosis factor-α antagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury.2011
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Hirai T, Watanabe S, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Baba H.
- Journal Title
  
  Spine (Phila Pa 1976)
  
  Volume: 36 Pages: 1350-1358
- NAID
  10030716262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791631
[Journal Article] Tumor necrosis factor-alpha antagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury2011
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Baba H
- Journal Title
  
  Spine
  
  Volume: 36 Pages: 1350-1358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791631
[Journal Article] High-mobility group box-1 and its receptors contribute to proinflammatory response in the acute phase of spinal cord injury in rats2011
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Hirai T, Rodriguez Guerrero A, Kobayashi S, Ma WY, Liu SY, Zhu P, Baba H
- Journal Title
  
  Spine(Phila Pa 1976)
  
  Volume: 36 Pages: 2122-2129
- NAID
  10030901954
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21343866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Ossification process involving the human thoracic ligamentura flavum : role of transcription factors2011
- Author(s)
  Uchida K, Yayama T, Cai HX, Nakajima H, Sugita D, Guerrero AR, Kobayashi S, Yoshida A, Chen KB, Baba H
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Microarray analysis of expression of cell death-associated genes in rat spinal cord cells exposed to cyclic tensile stresses in vitro2010
- Author(s)
  Uchida K, Nakajima H, Hirai T, Yayama T, Chen KB, Kobayashi S, Roberts S, Johnson WE, Baba H
- Journal Title
  
  BMC Neurosci
  
  Volume: 11 Pages: 84-84
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20663127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Microarray analysis of expression of cell death-associated genes in rat spinal cord cells exposed to cyclic tensile stresses in vitro.2010
- Author(s)
  Uchida K, Nakajima H, Hirai T, Yayama T, Chen KB, Kobayashi S, Roberts S, Johnson WE, Baba H.
- Journal Title
  
  BMC Neurosci
  
  Volume: 11 Pages: 84-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats.2010
- Author(s)
  Nakajima H, Uchida K, Yayama T, Kobayashi S, Guerrero AR, Furukawa S, Baba H.
- Journal Title
  
  Spine 35
  
  Pages: 497-504
- NAID
  10028062172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] 脊髄再生基礎科学の現状と近未来の展望、Myelopathyに対するアデノウィルスベクターを用いた逆行性神経栄養因子遺伝子療法による脊髄保護効果2010
- Author(s)
  内田研造、中嶋秀明、渡邉修司、馬場久敏
- Journal Title
  
  脊椎脊髄ジャーナル 23巻
  
  Pages: 859-866
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] 脊髄再生基礎科学の現状と近未来の展望、Myelopathyに対するアデノウィルスベクターを用いた逆行性神経栄養因子遺伝子療法による脊髄保護効果2010
- Author(s)
  内田研造、中嶋秀明、渡邉修司、馬場久敏
- Journal Title
  
  脊椎脊髄ジャーナル
  
  Volume: 23 Pages: 859-866
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats.2010
- Author(s)
  Nakajima H, Uchida K, Yayama T, Kobayashi S, Guerrero AR, Furukawa S, Baba H.
- Journal Title
  
  Spine
  
  Volume: 35 Pages: 497-504
- NAID
  10028062172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats2010
- Author(s)
  Nakajima H, Uchida K, Yayama T, Kobayashi S, Guerrero AR, Furukawa S, Baba H
- Journal Title
  
  Spine(Phila Pa 1976)
  
  Volume: 35 Pages: 497-504
- NAID
  10028062172
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20190624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy) sustaining chronic mechanical compression.2009
- Author(s)
  Inukai T, Uchida K, Nakajima H, Yayama T, Kobayashi S, Mwaka ES, Guerrero AR, Baba H.
- Journal Title
  
  Spine 34
  
  Pages: 2848-2857
- NAID
  10027250776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse(twy/twy)sustaining chronic mechanical compression.2009
- Author(s)
  Inukai T, Uchida K, Nakajima H, Yayama T, Kobayashi S, Mwaka ES, Guerrero AR, Baba H.
- Journal Title
  
  Spine 34
  
  Pages: 2848-2857
- NAID
  10027250776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Updates on ossification of posterior longitudinal ligament. Ossification front of posterior longitudinal ligament and cellular biological assessment of chronic mechanical compressed spinal cord2009
- Author(s)
  Uchida K, Nakajima H, Yayama T, Sato R, Baba H.
- Journal Title
  
  Clin Calcium 19
  
  Pages: 1472-1479
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Calcium pyrophosphate dehydrate crystal deposition in the ligamentum flavum of the cervical spine : histopathological and immunohistochemical findings.2009
- Author(s)
  Mwaka ES, Yayama T, Uchida K, Kobayashi S, Kokubo Y, Nakajima H, Sato R, Orwotho NT, Baba H
- Journal Title
  
  Clin Exp Rheumatol 27
  
  Pages: 430-438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] 損傷後頸髄神経細胞に対する逆行性神経栄養因子遺伝子導入2009
- Author(s)
  中嶋秀明, 内田研造, 犬飼智雄, 小林茂, 馬場久敏
- Journal Title
  
  中部日本整形外科災害外科学会雑誌 52
  
  Pages: 161-162
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse(twy/twy) sustaining chronic mechanical compression2009
- Author(s)
  Inukai T, Uchida K, Nakajima H, Yayama T, Kobayashi S, Mwaka ES, Guerrero AR, Baba H
- Journal Title
  
  Spine(Phila Pa 1976)
  
  Volume: 34 Pages: 2848-2857
- NAID
  10027250776
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19949368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Calcium pyrophosphate dehydrate crystal deposition in the ligamentum flavum of the cervical spine : histopathological and immunohistochemical findings2009
- Author(s)
  Mwaka ES, Yayama T, Uchida K, Kobayashi S, Kokubo Y, Nakajima H, Sato R, Orwotho NT, Baba H
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 27 Pages: 430-438
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19604435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] High-resolution magnetic resonance imaging and 18FDG-PET findings of the cervical spinal cord before and after decompressive surgery in patients with compressive myelopathy.2009
- Author(s)
  Uchida K, Nakajima H, Yayama T, Kobayashi S, Shimada S, Tsuchida T, Okazawa H, Mwaka E, Baba H
- Journal Title
  
  Spine 34
  
  Pages: 1185-1191
- NAID
  10027242864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Updates on ossification of posterior longitudinal ligament.Ossification front of posterior longitudinal ligament and cellular biological assessment of chronic mechanical compressed spinal cord.2009
- Author(s)
  Uchida K, Nakajima H, Yayama T, Sato R, Baba H.
- Journal Title
  
  Clin Calcium 19
  
  Pages: 1472-1479
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Gene expression profiles of neurotrophic factors in rat cultured spinal cord cells under cyclic tensile stress2008
- Author(s)
  Uchida K, Nakajima H, Takamura T, Furukawa S, Kobayashi S, Yavama T, Baba H
- Journal Title
  
  Spine 33
  
  Pages: 2596-2604
- NAID
  120001249811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] Adenovirus-mediated retrograde transfer of neurotrophin-3 gene enhances survival of anterior horn neurons of twy/twy mice with chronic mechanical compression of the spinal cord2008
- Author(s)
  Uchida K, Nakajima H, Inukai T, Takamura T, Kobayashi S, Furukawa S, Baba H.
- Journal Title
  
  J Neurosci Res 86
  
  Pages: 1789-1800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] Gene expression profiles of neurotrophic factors in rat cultured spinal cord cells under cyclic tensile stress2008
- Author(s)
  Uchida K, Nakajima H, Takamura T, Furukawa S, Kobayashi S, Yayama T, Baba H.
- Journal Title
  
  Spine 33
  
  Pages: 2596-2604
- NAID
  120001249811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] Adenovirus-mediated retrograde transfer of neurotrophin-3 gene enhances survival of anterior horn neurons of twy/twy mice with chronic mechanical compression of the spinal cord.2008
- Author(s)
  Uchida K, Nakajima H, Inukai T, Takamura T, Kobayashi S, Furukawa S, Baba H.
- Journal Title
  
  J Neurosci Res 86
  
  Pages: 1789-1800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] Target muscles for retrograde gene delivery to specific spinal cord segments2008
- Author(s)
  Nakajima H, Uchida K, Kobayashi S, Inukai T, Yayama T, Sato R, Mwaka E, Baba H
- Journal Title
  
  Neurosci Lett 435
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] Target muscles for retrograde gene delivery to specific spinal cord segments.2008
- Author(s)
  Nakajima H, Uchida K, Kobayashi S, Inukai T, Yayama T, Sato R, Mwaka E, Baba H.
- Journal Title
  
  Neurosci Lett 435
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] 脊髄損傷に対するアデノウィルスベクターを用いたBDNF遺伝子導入による神経保護効果2008
- Author(s)
  中嶋秀明
- Journal Title
  
  整形外科 59
  
  Pages: 1330-1330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] twymouse およびSCI modelにおけるアデノウィルスベクターを用いたBDNF/NT-3 gene transferの解析. 脊柱靭帯骨化症に関する調査研究2007
- Author(s)
  中嶋秀明, 内田研造, 犬飼智雄, 高村敬晴, 彌山峰史, 佐藤竜一郎, 馬場久敏
- Journal Title
  
  平成16年度総括研究報告書
  
  Pages: 86-91
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] 頚髄損傷モデルに対するBDNF遺伝子逆行性導入による前角細胞保護効果2007
- Author(s)
  中嶋秀明, 内田研造, 犬飼智雄, 高村敬晴, 小林茂, 馬場久敏
- Journal Title
  
  中部日本整形外科災害外科学会雑誌 50
  
  Pages: 887-888
- NAID
  10019781227
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] Rescue of rat anterior horn neurons after spinal cord injury by retrograde transfection of adenovirus vector carrying brain-derived neurotrophic factor gene.2007
- Author(s)
  Nakajima H, Uchida K, Kobayashi S, Inukai T, Horiuchi Y, Yayama T, Sato R, Baba H.
- Journal Title
  
  J Neurotrauma 24
  
  Pages: 703-712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791023
[Journal Article] Targeted retrograde transfection of adenovirus vector carrying brain-derived neurotrophic factor gene prevents loss of mouse (twy/twy) anterior horn neurons in vivo sustaining mechanical compression2006
- Author(s)
  Xu K, Uchida K, Nakajima H, Kobayashi S, Baba H
- Journal Title
  
  SPINE 31
  
  Pages: 1867-1874
- NAID
  10020590064
- Data Source
  KAKENHI-PROJECT-17790997
[Journal Article] Cervical Angina : A Seemingly Still Neglected Symptom of Cervical Spine Disorder?2006
- Author(s)
  Nakajima H., Uchida K., Kobayashi S., Kokubo Y., Yayama T., Sato R., Inukai T., Timbihurira G, Baba H.
- Journal Title
  
  Spinal Cord 44
  
  Pages: 509-513
- Data Source
  KAKENHI-PROJECT-17790997
[Journal Article] 頚髄損傷モデルに対する神経栄養因子発現アデノウィルスベクターを用いた遺伝子逆行性導入2006
- Author(s)
  中嶋秀明, 内田研造, 犬飼智雄, 彌山峰史, 佐藤竜一郎, 馬場久敏
- Journal Title
  
  脊柱靭帯骨化症に関する調査研究平成16年度総括研究報告書
  
  Pages: 86-91
- Data Source
  KAKENHI-PROJECT-17790997
[Journal Article] 頸髄損傷モデルに対するadenovirus vectorを用いたBDNF逆行性導入の検討2006
- Author(s)
  中嶋秀明, 内田研造, 犬飼智雄, 小林茂, 馬場久敏
- Journal Title
  
  中部日本整形外科災害外科学会雑誌 49
  
  Pages: 21-22
- Data Source
  KAKENHI-PROJECT-17790997
[Journal Article] Targeted retrograde gene delivery into the injured cervical spinal cord using recombinant adenovirus vector2005
- Author(s)
  Nakajima H, Uchida K, Kobayashi S, Kokubo Y, Yayama T, Sato R, Baba H.
- Journal Title
  
  Neuroscience Letter 385
  
  Pages: 30-35
- Data Source
  KAKENHI-PROJECT-17790997
[Journal Article] Cyclic Tensile Strain Facilitates the Ossification of Ligamentum Flavum Throughβ-Catenin Signaling Pathway
- Author(s)
  Uchida K, Yayama T, Cai CH, Nakajima H, Sugita D, Guerrero AR, Yoshida A, Baba H
- Journal Title
  
  In Vitro Analysis Spine(Phila Pa 1976)(in press)
  
  Volume: (in press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22158061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Rescue of rat anterior horn neurons after spinal cord injury by retrograde transfection of adenovirus vector carrying brain-derived neurotrophic factor gene
- Author(s)
  Nakajima H, Uchida K, Kobayashi S, Inukai T, Horiuchi Y, Yayama T, Sato R, Baba H
- Journal Title
  
  Journal of Neurotrauma (in press)
- Data Source
  KAKENHI-PROJECT-17790997
[Journal Article] Tumor necrosis factor-alpha antagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury.
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Baba H.
- Journal Title
  
  Spine
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Transplantation of Mesenchymal Stem Cells Promotes an Alternative Pathway of Macrophage Activation and Functional Recovery after Spinal Cord Injury
- Author(s)
  Nakajima H, Uchida K, Guerrero AR, Watanabe S, Sugita D, Takeura N, Yoshida A, Long G, Wright KT, Johnson WE, Baba H
- Journal Title
  
  J Neurotrauma
  
  Volume: (in press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22233298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Tumor necrosis factor-alpha antagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury.
- Author(s)
  Chen KB, Uchida K, Nakajima H, Yayama T, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Baba H.
- Journal Title
  
  Spine in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] High-mobility group box-1 and its receptors contribute to proinflammatory response in the acute phase of spinal cord injury in rats.
- Author(s)
  Uchida K, Nakajima H, Yayama T, Hirai T, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Zhu P, Baba H.
- Journal Title
  
  Spine in press
- NAID
  10030901954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] High-mobility group box-1 and its receptors contribute to proinflammatory response in the acute phase of spinal cord injury in rats.
- Author(s)
  Uchida K, Nakajima H, Yayama T, Hirai T, Guerrero AR, Kobayashi S, Ma WY, Liu SY, Zhu P, Baba H.
- Journal Title
  
  Spine
  
  Volume: (in press)
- NAID
  10030901954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791389
[Journal Article] Cyclic Tensile Strain Facilitates the Ossification of Ligamentum Flavum Through β-Catenin Signaling Pathway. In Vitro Analysis
- Author(s)
  Uchida K, Yayama T, Cai CH, Nakajima H, Sugita D, Guerrero AR, Yoshida A, Baba H
- Journal Title
  
  Spine
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Journal Article] Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice
- Author(s)
  Guerrero AR, Uchida K, Nakajima H, Watanabe S, Nakamura M, Johnson WE, Baba H
- Journal Title
  
  J Neuroinflammation
  
  Volume: (in press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22369693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] PK11195 PET imagingを用いた脊髄内活性化ミクログリア動態評価と臨床的有用性2021
- Author(s)
  北出誠、中嶋秀明、渡邉修司、本定和也、松峯昭彦
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09645
[Presentation] 急性脊髄損傷後慢性期までの脳－脊髄におけるmicroglia/macrophageの動態解析2021
- Author(s)
  窪田有咲、中嶋秀明、渡邉修司、本定和也、松峯昭彦
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09645
[Presentation] 脊髄損傷後の損傷部および腰膨大部におけるactivated microgliaおよびhematogenous macrophageの動態と極性2020
- Author(s)
  窪田有咲、中嶋秀明、渡邉修司、本定和也、松峯昭彦
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09645
[Presentation] 脊髄損傷後の損傷部および腰膨大部におけるactivated microgliaおよびhematogenous macrophageの動態と極性2020
- Author(s)
  窪田有咲、中嶋秀明、渡邉修司、本定和也、松峯昭彦
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09059
[Presentation] Neuropathic pain after spinal cord injury relieves in CCL21 knockout (plt) mouse through decreasing of M1 type microglia/macrophage and inflammatory cytokines at the injured site and lumbar enlargement2019
- Author(s)
  Nakajima H, Watanabe S, Honjoh K, Matsumine A
- Organizer
  Cervical Spine Research Society European Section Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09059
[Presentation] 頚髄損傷モデルにおけるtranslocator protein（TSPO）発現とPK11195 PET imagingによる動態解析2019
- Author(s)
  北出誠、中嶋秀明、渡邉修司、本定和也、松峯昭彦
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09645
[Presentation] Clinical assessment using PK11195 PET/MRI imaging for neuropathic pain in the patients with cervical spinal cord injury and compressive myelopathy.2018
- Author(s)
  Nakajima H, Kitade M, Watanabe S, Honjoh K, Yamamoto Y, Matsumine A.
- Organizer
  Cervical Spine Research Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] CCL21欠損マウス脊髄損傷モデルにおけるbelow-levelの疼痛と炎症性サイトカインによるmicroglia/macrophage phenotypeの変化2018
- Author(s)
  本定和也、中嶋秀明、高橋藍、山本悠介、出淵雄哉、松峯昭彦
- Organizer
  第47回日本脊椎脊髄病学会
- Data Source
  KAKENHI-PROJECT-18K09059
[Presentation] CCL21欠損マウス脊髄損傷モデルにおける損傷部・腰膨大部の炎症性サイトカインによるM1/M2 phenotypeの変化2018
- Author(s)
  本定和也、中嶋秀明、高橋藍、山本悠介、出淵雄哉、松峯昭彦
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09059
[Presentation] PK11195 PET imagingを用いた脊髄内活性化ミクログリア可視化の試み2018
- Author(s)
  中嶋秀明、北出誠、渡邉修司、本定和也、山本悠介、松峯昭彦
- Organizer
  第47回日本脊椎脊髄病学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] ラット脊髄損傷におけるmicrogliaの[11C]-PK11195によるPETイメージング2017
- Author(s)
  北出誠、中嶋秀明、渡邉修司、他.
- Organizer
  第32回日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] Clinical assessment using MRI/18F-FDG PET fusion imaging for patients with cervical compressive myelopathy2017
- Author(s)
  Nakajima H, Honjoh K, Watanabe S, et al.
- Organizer
  Cervical Spine Research Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] ラット脊髄損傷におけるmicrogliaの［11C］-PK11195によるPETイメージング2016
- Author(s)
  北出　誠, 中嶋秀明, 渡邉修司, 他
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] 脊髄再生と疼痛2016
- Author(s)
  中嶋秀明
- Organizer
  第38回日本疼痛学会
- Place of Presentation
  北海道立道民活動センター（北海道札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] 慢性脊髄圧迫モデルにおける血管脊髄関門機能変化と脊髄障害性疼痛発現2016
- Author(s)
  竹浦直人, 中嶋秀明, 髙橋藍, 本定和也, 内田研造
- Organizer
  第89回日本整形外科学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K10391
[Presentation] CCL21欠損マウス脊髄損傷モデルにおける疼痛関連評価および損傷部・腰膨大部のmicroglia/ macrophage phenotypeと炎症性サイトカインの評価2016
- Author(s)
  本定和也, 中嶋秀明, 髙橋　藍, 他
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] 圧迫性頚髄症モデル（twyマウス）を用いた脊髄障害性疼痛に関する基礎的研究2016
- Author(s)
  竹浦直人, 中嶋秀明, 高橋藍, 本定和也, 北出誠, 小久保安朗
- Organizer
  第126回中部日本整形外科災害外科学会・学術集会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15K10391
[Presentation] 脊骨髄間葉系幹細胞移植は疼痛関連シグナルおよび炎症細胞浸潤抑制を介して脊髄損傷後疼痛抑制に寄与する2016
- Author(s)
  中嶋秀明, 渡邉修司, 本定和也, 他
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] 慢性圧迫脊髄におけるMRI輝度変化と血液脊髄関門の透過性変化2016
- Author(s)
  竹浦直人, 中嶋秀明, 髙橋　藍, 他
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10817
[Presentation] 圧迫性頚髄症に伴う慢性疼痛における血液脊髄関門を介したmacrophageの動態2015
- Author(s)
  竹浦直人, 中嶋秀明, 高橋藍, 渡邉修司, 本定和也, 北出誠, 杉田大輔, 内田研造
- Organizer
  第8回日本運動器疼痛学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-15K10391
[Presentation] 脊髄損傷部および腰膨大部におけるhematogenous macrophageおよびresident microgliaの動態2015
- Author(s)
  中嶋秀明、内田研造、渡邉修司、本定和也
- Organizer
  第44回日本脊椎脊髄病学会
- Place of Presentation
  福岡
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25462290
[Presentation] 脊髄損傷に対する間葉系幹細胞移植後の脊髄再生2015
- Author(s)
  内田研造、中嶋秀明、渡邉修司、髙橋藍、本定和也
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462290
[Presentation] ヒト頸椎OPLLにおけるメカニカルストレスが骨化前線部の内軟骨骨化に関与する転写因子に与える影響の検討2015
- Author(s)
  杉田大輔, 内田研造, 中嶋秀明, 小久保安朗, 山岸淳嗣, 吉田藍, 馬場久敏
- Organizer
  第44回日本脊椎脊髄病学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26462235
[Presentation] 慢性脊髄圧迫に伴う疼痛にblood‐spinal cord barrierの破綻が関与している2015
- Author(s)
  竹浦直人, 中嶋秀明, 吉田藍, 本定和也, 内田研造
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場ほか
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K10391
[Presentation] OPLL骨化前線におけるIhhとその受容体GLI2、GLI3、Patched1の発現に関する検討2015
- Author(s)
  杉田大輔, 中嶋秀明, 竹浦直人, 吉田藍, 本定和也, 内田研造
- Organizer
  第30回日本整形外科基礎学術集会
- Place of Presentation
  富山国際会議場
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26462235
[Presentation] 損傷脊髄内移植骨髄間質細胞の細胞死メカニズムと抗IL-6受容体抗体併用による移植効率改善効果2013
- Author(s)
  中嶋秀明、内田研造、渡邉修司、Alexander Rodriguez Guerrero、本定和也、馬場久敏
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉(幕張メッセ)
- Data Source
  KAKENHI-PROJECT-25462290
[Presentation] Blockade of interleukin-6 signaling improves the survival rate of transplanted bone marrow stromal cells and increases locomotory function in mice with spinal cord injury2013
- Author(s)
  K.Uchida, H.Nakajima, Ying Tan, S.Watanabe, M.Kitade, William E. B. Johnson, H.Baba
- Organizer
  The 15th Spinal Research Network Meeting
- Place of Presentation
  London UK
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] 脊髄損傷後疼痛に対する骨髄間質細胞移植の有効性の検討2013
- Author(s)
  渡邉　修司, 内田　研造, 中嶋　秀明, 松尾　英明, 竹浦　直人, 吉田　藍, 馬場　久敏
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉県　千葉市　幕張メッセ
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] 抗IL-6受容体抗体が脊髄損傷後移植骨髄間質細胞の生存率に与える影響2013
- Author(s)
  中嶋秀明、内田研造、渡邉修司、Tan Ying、Alexander Rodriguez Guerrero、馬場久敏
- Organizer
  第42回脊椎脊髄病学会
- Place of Presentation
  沖縄（沖縄コンベンションセンター）
- Data Source
  KAKENHI-PROJECT-25462290
[Presentation] Dynamic state and localization of microglia in injured spinal cord by the peripheral benzodiazepine receptor ligand PK111952013
- Author(s)
  S.Watanabe, K.Uchida, H.Nakajima, T.Hirai, H.Baba
- Organizer
  Euro Spine 2013
- Place of Presentation
  Liverpool　UK
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] 脊髄損傷急性期における抗IL-6受容体抗体投与によるmacrophage極性変化と機能改善効果2013
- Author(s)
  中嶋秀明、内田研造、Alexander Guerrero、渡邉修司、馬場久敏
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-25462290
[Presentation] 抗IL-6抗体投与が移植骨髄間質細胞の生存率に与える影響2013
- Author(s)
  中嶋秀明、内田研造、渡邉修司、Tan Ying、Alexander Rodriguez Guerrero、馬場久敏
- Organizer
  第86回日本整形外科学会
- Place of Presentation
  広島(リーガロイヤルホテル広島）
- Data Source
  KAKENHI-PROJECT-25462290
[Presentation] 脊髄障害性疼痛症候群の実態の把握と病態の解明に関する研究―全国二次アンケート調査の結果報告―2013
- Author(s)
  内田　研造, 馬場　久敏, 中嶋　秀明, 田口　敏彦, 山下　敏彦, 中村　雅也, 牛田　享宏
- Organizer
  第86回日本整形外科学会学術総会
- Place of Presentation
  広島県　広島市　広島グリーンアリーナ
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] 脊髄損傷モデルの慢性疼痛の解析および骨髄間質細胞移植の与える効果についての検討2013
- Author(s)
  渡邉　修司, 内田　研造, 中嶋　秀明, 吉田　藍, 竹浦　直人, 馬場　久敏
- Organizer
  第42回日本脊椎脊髄病学会
- Place of Presentation
  沖縄県　宜野湾市　沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] Cyclic tensile stress upregulates the expression of β-catenin signaling in cultured cells harvested from human ossified ligamentum flavum2012
- Author(s)
  彌山峰史, 内田研造, 中嶋秀明, 杉田大輔, 馬場久敏
- Organizer
  Annual Meeting of the Orthopaedic Research Society 2012
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] Transplantation of mesenchymal stem cells drrived from bone marrow after spinal cord injury contribute functional recovery and tissue regeneration by promoting alternative pathway of macrophage activation2012
- Author(s)
  Nakajima H, Uchida K, Guerrero AR, Watanabe S, Takeura N, Yoshida A, Baba H
- Organizer
  International Society of Stem Cell Research Annual Meeting
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] 骨間質細胞移植が脊髄損傷後微小環境の変化.2012
- Author(s)
  中嶋秀明
- Organizer
  第41回日本脊椎脊髄病学会学術集会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] 骨髄由来間葉系幹細胞移植が脊髄損傷後急性期におけるmacrophage分画に与える影響.2012
- Author(s)
  中嶋秀明
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] 骨髄間質細胞移植が脊髄損傷後 macrophage の動態に与える影響2012
- Author(s)
  中嶋秀明、内田研造、Alexander Rodriguez Guerrero、渡邉修司、杉田大輔、竹浦直人、馬場久敏
- Organizer
  第85回日本整形外科学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] Cycli ctensile stress upregulates the expression ofβ-catenin signaling in cultured cells harvested from human ossified ligamentum flavum2012
- Author(s)
  彌山峰史,内田研造,中嶋秀明,杉田大輔,馬場久敏
- Organizer
  Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 骨髄間質細胞移植が脊髄損傷後macrophageの動態に与える影響.2012
- Author(s)
  中嶋秀明
- Organizer
  第85回日本整形外科学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] 骨間質細胞移植が脊髄損傷後微小環境の変化2012
- Author(s)
  中嶋秀明、内田研造、Alexander Rodriguez Guerrero、渡邉修司、杉田大輔、竹浦直人、吉田藍、馬場久敏
- Organizer
  第41回日本脊椎脊髄病学会学術集会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] Transplantation of mesenchymal stem cells drrived from bone marrow after spinal cord injury contribute functional recovery and tissue regeneration by promoting alternative pathway of macrophage activation.2012
- Author(s)
  Nakajima H
- Organizer
  International Society of Stem Cell Research Annual Meeting
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] 培養骨化靱帯細胞における転写因子の発現とtensile stressの影響2011
- Author(s)
  彌山峰史,内田研造,中嶋秀明,小久保安朗,杉田大輔, Cai Hong-xin,吉田藍,馬場久敏
- Organizer
  第40回日本脊椎脊髄病学会
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] Cyclic tensile stress が胸椎黄色靭帯の骨化形成に与える影響-内軟骨性骨化過程におけるWnt β-catenin signalingの関与-2011
- Author(s)
  彌山峰史, 内田研造, 中嶋秀明, 杉田大輔, 馬場久敏
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] Transplanted bone marrow stromal cells promote functional recovery, tissue regeneration withproduction of neuroprotectivemacrophage after spinal cord injury2011
- Author(s)
  Nakajima H, Uchida K, Alexander Rodriguez G, Yayama T, Watanabe S, Baba H
- Organizer
  The 39th CSRS Annual Meeting
- Place of Presentation
  Arizona, USA
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] 脊髄損傷に対する骨髄由来Mesenchymal Syem Cell移植の有用性の検討-急性期における macrophage phenotype に与える影響-2011
- Author(s)
  中嶋秀明、内田研造、Alexander Rodriguez Guerrero、渡邉修司、杉田大輔、竹浦直人、吉田藍、馬場久敏
- Organizer
  第30回日本運動器移植・再生医学研究会
- Place of Presentation
  福岡
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] 培養骨化靭帯細胞における転写因子の発現とtensile stressの影響2011
- Author(s)
  彌山峰史, 内田研造, 中嶋秀明, 小久保安朗, 杉田大輔, Cai Hong-xin, 吉田藍, 馬場久敏
- Organizer
  第40回日本脊椎脊髄病学会
- Place of Presentation
  (Web開催)
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 脊柱靭帯骨化における骨化前線部の軟骨細胞分化の特徴2011
- Author(s)
  彌山峰史, 内田研造, 杉田大輔, 中嶋秀明, 小久保安朗, 渡邉修司, 吉田藍, 竹浦直人, 馬場久敏
- Organizer
  第30回日本運動器移植・再生医学研究会
- Place of Presentation
  福岡
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 脊柱靭帯骨化における骨化前線部の軟骨細胞分化の特徴.2011
- Author(s)
  彌山峰史,内田研造,杉田大輔,中嶋秀明,小久保安朗,渡邉修司,吉田藍,竹浦直人,馬場久敏
- Organizer
  第30回日本運動器移植・再生医学研究会
- Place of Presentation
  福岡
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] Prevention of the development of inflammatory tissue damage and apoptosis of neurons and oligodendroglia after spinal cord injury by tumor necrosis factor-alpha antagonist2011
- Author(s)
  Nakajima H, Uchida K, Chen KB, Hirai T, Alexander Rodriguez G, Sugita D, Baba H
- Organizer
  The CSRS Eurpearn Section Annual Meeting
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-23791631
[Presentation] Cyclic tensile stressが胸椎黄色靱帯の骨化形成に与える影響-内軟骨性骨化過程におけるWntβ-catenin signalingの関与-2011
- Author(s)
  彌山峰史,内田研造,中嶋秀明,杉田大輔,馬場久敏
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 胸椎黄色靱帯骨化の骨化過程における転写因子の役割2010
- Author(s)
  彌山峰史、内田研造、Cai HX、小林茂、佐藤竜一郎、小久保安朗、中嶋秀明、杉田大輔、馬場久敏
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 脊髄損傷に対する移植ヒト骨髄間質細胞の動態と治療効果2010
- Author(s)
  中嶋秀明, 他
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] (1)脊髄損傷に対するアデノウィルスベクターを用いた神経栄養因子遺伝子逆行性導入による神経保護効果2010
- Author(s)
  中嶋秀明, 他
- Organizer
  第29回運動器移植・再生医学研究会
- Place of Presentation
  滋賀
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] 脊髄損傷における神経栄養因子遺伝子逆行性導入による神経グリア系細胞の保護効果2010
- Author(s)
  中嶋秀明, 他
- Organizer
  第39回日本脊椎脊髄病学会学術集会
- Place of Presentation
  高知
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] Topographic expression of transcriptional factors in the human ossification of ligamentum flavum in thoracic spine2010
- Author(s)
  Yayama T, Uchida K, Cai HX, Kobayashi S, Nakajima H, Sato R, Sugita D, Alexander Guerrero, Chen KB, Baba H
- Organizer
  7^<th> Combined Meeting of ORS
- Place of Presentation
  KYOTO
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 脊髄損傷に対するアデノウィルスベクターを用いた神経栄養因子遺伝子逆行性導入による神経保護効果2010
- Author(s)
  中嶋秀明, 他
- Organizer
  第29回運動器移植・再生医学研究会
- Place of Presentation
  滋賀
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] Topographic expression of transcriptional factors in the human ossific ation of ligamentum flavum in thoracic spine2010
- Author(s)
  Yayama T, Uchida K, Cai HX, Kobayashi S, Nakajima H, Sato R, Sugita D, Alexander Guerrero, Chen KB, Baba H
- Organizer
  7^(th) Combined Meeting of ORS
- Place of Presentation
  Kyoto
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] Cell death-associated genes expression patterns using microarray analysis in rat cultured spinal cord cells exposed to cyclic tensile stresses in vitro2010
- Author(s)
  K.Uchida, H.Nakajima, T.Hirai, T.Yayama, D.Sugita, S.Kobayashi, H.Baba
- Organizer
  7＾<th> Combined Meeting of ORS
- Place of Presentation
  京都
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 慢性脊髄圧迫モデル(twy/twy)に対する神経栄養因子遺伝子導入による再生能力賦活化効果2010
- Author(s)
  中嶋秀明, 他
- Organizer
  第9回再生医療学会
- Place of Presentation
  広島
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] 損傷脊髄におけるHigh mobility group box-1(HMGB-1)の動態と役割2010
- Author(s)
  中嶋秀明, 他
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] 培養骨化靱帯細胞における機械的ストレスと骨形成誘導因子2010
- Author(s)
  彌山峰史、内田研造、Cai HX、中嶋秀明、小久保安朗、小林茂、杉田大輔、馬場久敏
- Organizer
  第29回日本運動器移植・再生医学研究会
- Place of Presentation
  京都
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] Cell death-associated genes expression patterns using microarray analysis in rat cultured spinal cord cells exposed to cyclic tensile stresses in vitro2010
- Author(s)
  K. Uchida, H. Nakajima, T. Hirai, T. Yayama, D. Sugita, S. Kobayashi, H. Baba
- Organizer
  7^<th> Combined Meeting of ORS
- Place of Presentation
  KYOTO
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 損傷脊髄におけるHighmobility group box -1(HMGB-1)の動態と役割2010
- Author(s)
  中嶋秀明, 他
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] 損傷後頚髄に対するBDNF遺伝子逆行性導入を用いたneuronおよびoligodendrocyteの賦活化効果2009
- Author(s)
  中嶋秀明, 他
- Organizer
  第24回日本整形外科学会基礎学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] Gene expression profiles of neurotrophic factors and their receptors in rat cultured spinal cord cells under cyclic tensile stress2009
- Author(s)
  Uchida K, Nakajima H, Hirai T, Inukai T, Chen K, Alexander G, Yayama T, Baba H
- Organizer
  37^<th> Annual Meeting of the Cervical Spine Research Society
- Place of Presentation
  Salt Lake City
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21591895
[Presentation] 慢性脊髄圧迫モデル(twy/twy)に対する逆行性神経栄養因子遺伝子導入を用いたneuronおよびoligodendrocyteの賦活化効果2009
- Author(s)
  中嶋秀明, 他
- Organizer
  第24回日本整形外科学会基礎学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] 慢性脊髄圧迫モデル(twy/twy)に対する逆行性神経栄養因子遺伝子導入を用いたneuronおよびohgodendrocyteの賦活化効果2009
- Author(s)
  中嶋秀明、内田研造、犬飼智雄、彌山峰史、Chen Kebing、小林茂、馬場久敏
- Organizer
  第24回日本整形外科学会基礎学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] 損傷脊髄内神経栄養因子遺伝子逆行性導入による神経グリア系細胞に対する賦活化効果2009
- Author(s)
  中嶋秀明, 他
- Organizer
  第38回日本脊椎脊髄病学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2009-04-25
- Data Source
  KAKENHI-PROJECT-21791389
[Presentation] 損傷後頚髄神経細胞に対する逆行性神経栄養因子遺伝子導入2008
- Author(s)
  中嶋秀明, 他
- Organizer
  第111回中部日本整形外科災害外科学会学術集会
- Place of Presentation
  京都
- Year and Date
  2008-04-12
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 脊髄損傷モデルに対する逆行性神経栄養因子遺伝子導入が及ぼす神経細胞保護効果2008
- Author(s)
  中嶋秀明, 他
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  奈良
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 慢性脊髄圧迫モデル(twy/twy)に対する脊髄前角細胞への選択的神経栄養因子遺伝子導入2008
- Author(s)
  中嶋秀明, 他
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  奈良
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 頚髄損傷に対する神経栄養因子遺伝子導入による前角細胞保護効果2007
- Author(s)
  中嶋秀明、内田研造、犬飼智雄、高村敬晴、小林茂、馬場久敏
- Organizer
  第42回脊髄障害医学学会
- Place of Presentation
  大宮
- Year and Date
  2007-11-10
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 脊髄損傷に対するアデノウィルスベクターを用いたBDNF遺伝子導入による神経保護効果2007
- Author(s)
  中嶋秀明, 他
- Organizer
  第22回日本整形外科学会基礎学術集会パネルディスカッション
- Place of Presentation
  浜松
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 脊髄損傷に対するアデノウィルスベクターを用いたBDNF遺伝子導入による神経保護効果2007
- Author(s)
  中嶋秀明、内田研造、犬飼智雄、高村敬晴、小林茂、馬場久敏
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  浜松
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 脊髄損傷に対するアデノウィルスベクターを用いた神経栄養因子遺伝子逆行性導入による神経保護効果2007
- Author(s)
  中嶋秀明、内田研造、犬飼智雄、小林茂、馬場久敏
- Organizer
  第26回日本運動器移植・再生医学研究会
- Place of Presentation
  浜松
- Year and Date
  2007-10-27
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 前角細胞への逆行性遺伝子導入におけるTarget Organの選択2007
- Author(s)
  中嶋秀明, 他
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  浜松
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] 脊髄前角細胞への逆行性遺伝子導入におけるTarget Organの選択2007
- Author(s)
  中嶋秀明、内田研造、犬飼智雄、高村敬晴、小林茂、馬場久敏
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  浜松
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] twy mouseおよびSCI modelにおけるアデノウィルスベクターを用いたBDNF/NT-3 gene transferの解析2007
- Author(s)
  中嶋秀明、内田研造、犬飼智雄、高村敬晴、彌山峰史、佐藤竜一郎、馬場久敏
- Organizer
  平成19年度第2回脊柱靭帯骨化症研究班班会議
- Place of Presentation
  東京大学
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19791023
[Presentation] メカニカルストレスはヒトOPLLにおいてインディアンヘッジホッグ (Ihh)とその受容体の発現増加を促進させ軟骨細胞の成長を進行させる
- Author(s)
  杉田大輔、内田研造、中嶋秀明、本定和也、坂本拓己、山岸淳嗣、馬場久敏
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島市
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26462234
[Presentation] 頸椎OPLLの骨化前部における軟骨細胞分化、肥大に関する転写因子のマイクロアレイを用いた検討
- Author(s)
  杉田大輔、内田研造、中嶋秀明、竹浦直人、吉田藍、馬場久敏
- Organizer
  第122回中部日本整形外科災害外科学会・学術集会
- Place of Presentation
  岡山市
- Year and Date
  2014-04-11 – 2014-04-12
- Data Source
  KAKENHI-PROJECT-26462234
[Presentation] Early transplantation of mesenchymal stem cells after spinal cord injury relieves pain hypersensitivity through suppression of pain-related signaling cascades and reduced inflammatory cell recruitment
- Author(s)
  K Uchida, H Nakajima, S Watanabe, K Honjoh, William E B Johnson, H Baba
- Organizer
  The 16th Spinal Research Network Meeting
- Place of Presentation
  London（United Kingdom）
- Year and Date
  2014-09-05 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] 脊髄障害性疼痛におけるミクログリア/マクロファージの活性化分子メカニズム
- Author(s)
  内田研造, 中嶋秀明, 馬場久敏
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島市、城山観光ホテル
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] Indian Hedgehog signaling induces hypertrophy and differentiation of chondrocytes in the ossification front of human cervical OPLL.
- Author(s)
  Sugita D, Uchida K, Nakajima H, Watanabe S, Yoshida A, Baba H.
- Organizer
  Euro Spine 2014
- Place of Presentation
  Lyon (France)
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26462234
[Presentation] Quantitative analysis and prognostic value of changes in spinal cord signal intensity on magnetic resonance imaging in patients with cervical compressive myelopathy
- Author(s)
  H Nakajima, K Uchida, N Takeura, K Honjoh, T Sakamoto, H Baba
- Organizer
  Euro Spine 2014
- Place of Presentation
  Lyon（France）
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] 頚椎後縦靭帯骨化症の骨化巣における軟骨細胞分化・肥大に関する遺伝子学的解析
- Author(s)
  杉田大輔, 内田研造, 中嶋秀明, 渡邉修司, 竹浦直人, 吉田幸男, 馬場久敏
- Organizer
  第43回日本脊椎脊髄病学会学術集会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-04-17 – 2014-04-19
- Data Source
  KAKENHI-PROJECT-26462235
[Presentation] Chronic progressive compression induces the phenotype changes of the activated microglia/macrophages in the spinal cord of spinal hyperostotic twy/twy mouse: Implications in human cervical compressive myelopathy
- Author(s)
  T Hirai, K Uchida, H Nakajima, T Inukai, N Takeura, S Watanabe, H Baba
- Organizer
  Euro Spine 2014
- Place of Presentation
  Lyon（France）
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] GFPマウス骨髄を移植したtwyキメラマウスを用いた慢性疼痛に関する免疫組織学的検討
- Author(s)
  竹浦直人, 内田研造, 中嶋秀明, 渡邉修司, 吉田藍, 本定和也, 馬場久敏
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島市、城山観光ホテル
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24390351
[Presentation] メカニカルストレスはヒトOPLLにおいてIhhとその受容体の発現を増加させ軟骨細胞肥大を進行させる
- Author(s)
  杉田大輔, 内田研造, 中嶋秀明, 本定和也, 坂本拓己, 山岸淳嗣, 馬場久敏
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島（城山観光ホテル）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26462235
[Presentation] 頸椎後縦靭帯骨化症の骨化巣における軟骨細胞分化・肥大に関する遺伝子学的検討
- Author(s)
  杉田大輔、内田研造、中嶋秀明、竹浦直人、吉田藍、馬場久敏
- Organizer
  第43回日本脊椎脊髄病学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-17 – 2014-04-19
- Data Source
  KAKENHI-PROJECT-26462234
[Presentation] 脊髄圧迫・損傷における神経生物学的可塑性と再生医学的応答
- Author(s)
  馬場久敏, 中嶋秀明, 竹浦直人, 吉田藍, 渡邉修司, 犬飼智雄, William E B Johnson, 内田研造
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島市、城山観光ホテル
- Year and Date
  2014-10-09 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-24390351

1. UCHIDA Kenzo (60273009)

# of Collaborated Projects: 6 results

# of Collaborated Products: 78 results
2. BABA Hisatoshi (00165060)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
3. Takeura Naoto (00615304)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. Sugita Daisuke (90596678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. Hirai Takayuki (30569132)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 渡邉修司 (00596679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. USHIDA Takahiro (60304680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 高橋藍 (90615303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakajima Hideaki 中嶋 秀明

NAKAJIMA Hideaki 中嶋 秀明

Research Projects

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Co-Researchers

脊柱靭帯骨化由来エクソソーム抗膜タンパク抗体による疾患活動性評価と骨化進展抑制Principal Investigator

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膜タンパク陽性エクソソームによる脊柱靱帯骨化の疾患活動性評価法の開発と機能解析Principal Investigator

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Assessments of neuron-glia linkage in spinal cord-related pain and clinical significance of neuroimaging (PK11195 PET/MRI)Principal Investigator

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The assessment of molecular/cellular pathophysiology and the development of neuroimaging for spinal cord-related painPrincipal Investigator

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The basic reaserch for the pathologic symptom to improve the survival rate of transplanted bone marrow stromal cells in the injured spinal cordPrincipal Investigator

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Nakajima Hideaki 中嶋秀明

NAKAJIMA Hideaki 中嶋秀明

[Book] Case Library Series　痛みの診療ベストプラクティス2014