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SHIMBARA Takuya  新原 琢也

ORCIDConnect your ORCID iD *help
Researcher Number 10398266
Affiliation (based on the past Project Information) *help 2007: 宮崎大, 医学部, 研究員
2006: UNIVERSITY OF MIYAZAKI, FACULTY OF MEDICINE, ASSISTANT PROFESSOR, 医学部, 助手
2005: 宮崎大学, 医学部, COEリサーチアソシエイト
Review Section/Research Field
Principal Investigator
Applied health science
Except Principal Investigator
Gastroenterology / Biological Sciences
Keywords
Principal Investigator
身体運動 / 成長ホルモン / ソマトポーズ / アディポサイトカイン / 脂肪細胞 / グレリン
Except Principal Investigator
高感度RIA系 / 腫瘍細胞株 / Ca^<2+>イメージング装置 / オーファン受容体 … More / ペプチドの網羅的解析 / RIA / tumor cell lines / IMACS / orphan receptor / peptidomics analysis / gut peptide / 消化管ペプチド / vgf / アルツハイマー病 / NERP / 脳アミロイド / BRI / Ca^<2+>イメージング / 摂食・エネルギー代謝調節 Less
  • Research Projects

    (3 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (9 People)
  •  ペプチドーム解析を応用した脳機能調節に作用する新規ペプチドの探索と機能研究

    • Principal Investigator
      NAKAZATO Masamitsu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Miyazaki
  •  エネルギー代謝調節ペプチドグレリンの脂肪組織に対する作用Principal Investigator

    • Principal Investigator
      新原 琢也
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied health science
    • Research Institution
      University of Miyazaki
  •  Identification of novel bioactive gut peptides and clarification of feeding regulation of brain-gut axis

    • Principal Investigator
      MONDAL M・S
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Miyazaki

All 2008 2007 2006 2005 2004 Other

All Journal Article

  • [Journal Article] Vagal afferent pathway does not play a major on satiety induced by intestinal fatty acid.2008

    • Author(s)
      Ogawa N, Yamaguchi H, Shimbara T, Toshinai K, Kakutani M, Yonemori F, Nakazato M
    • Journal Title

      Neurosci Lett 433

      Pages: 38-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Ontogeny of a new enteric peptide, neuropeptide W(NPW), in the developing rat stomach.2007

    • Author(s)
      Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M
    • Journal Title

      Regul Pept 145

      Pages: 141-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men2007

    • Author(s)
      Toshinai T, Kawagoe T, Shimbara T, Tobina T, Nishida Y, Mondal MS, Yamaguchi H, Date Y, Tanaka H, Nakazato M
    • Journal Title

      Horm Metab Res 39

      Pages: 849-851

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and-22007

    • Author(s)
      Yamaguchi H, Sasaki K, Satomi Y, Shimbara T, Kageyama H, Mondal MS, Toshinai K, Date Y, Gonzalez LJ, Shioda S, Takao T, Nakazato M, Minamino N
    • Journal Title

      J Biol Chem 282

      Pages: 26354-26360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

    • Author(s)
      Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
    • Journal Title

      Mech Ageing Dev 128

      Pages: 182-186

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

    • Author(s)
      Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
    • Journal Title

      Mech Ageing Dev, 128

      Pages: 182-186

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

    • Author(s)
      Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
    • Journal Title

      Mech Ageing Dev 128

      Pages: 715-721

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

    • Author(s)
      Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
    • Journal Title

      Mech Ageing Dev. 128(2)

      Pages: 182-186

    • Data Source
      KAKENHI-PROJECT-18700555
  • [Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men2007

    • Author(s)
      Toshinai K, Kawagoe T, Shimbara T, Tobina T, Nishida Y, Mondal MS, Yamaguchi H, Date Y, Tanaka H, Nakazato M
    • Journal Title

      Horm Metab Res 39

      Pages: 849-851

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006

    • Author(s)
      Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M
    • Journal Title

      Endocrinology 147

      Pages: 2306-2314

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus.2006

    • Author(s)
      Date Y, Shimbara T, Koda S, Toshinai K, Ida T, Murakami N, Miyazato M, Kokame K, Ishizuka Y, Ishida Y, Kageyama H, Shioda S, Kangawa K, Nakazato M
    • Journal Title

      Cell Metab 4

      Pages: 323-331

    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006

    • Author(s)
      Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M
    • Journal Title

      Endocrinology 147

      Pages: 2306-2314

    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006

    • Author(s)
      Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M.
    • Journal Title

      Endocrinology 147

      Pages: 2043-2050

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006

    • Author(s)
      Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M.
    • Journal Title

      Endocrinology 147

      Pages: 2306-2314

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006

    • Author(s)
      Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M
    • Journal Title

      Endocrinology 147

      Pages: 2043-2050

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006

    • Author(s)
      Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M
    • Journal Title

      Endocrinology 147

      Pages: 2043-2050

    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumonia.2006

    • Author(s)
      Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS, Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M.
    • Journal Title

      Eur Respir J 27

      Pages: 253-260

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumonia.2006

    • Author(s)
      Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS, Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M
    • Journal Title

      Eur Respir J 27

      Pages: 253-260

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus.2006

    • Author(s)
      Date Y, Shimbara T(contributed equally as first author), Koda S, Toshinai K, Ida T, Murakami N, Miyazato M, Kokame K, Ishizuka Y, Ishida Y, Kageyama H, Shioda S, Kangawa K, Nakazato M
    • Journal Title

      Cell Metab. 4(4)

      Pages: 253-260

    • Data Source
      KAKENHI-PROJECT-18700555
  • [Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006

    • Author(s)
      Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M.
    • Journal Title

      Endocrinology, 147

      Pages: 2306-2314

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumon a.2006

    • Author(s)
      Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS, Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M.
    • Journal Title

      Eur Respir J, 27

      Pages: 253-260

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006

    • Author(s)
      Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M.
    • Journal Title

      Endocrinology, 147

      Pages: 2043-2050

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumonia.2005

    • Author(s)
      Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS.Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M
    • Journal Title

      Eur Respir J 27

      Pages: 253-260

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Central administration of ghrelin preferentially enhances fat ingestion.2004

    • Author(s)
      Shimbara T, Mondal MS, Kawagoe T, Toshinai K, Koda S, Yamaguchi H, Date Y, Nakazato M.
    • Journal Title

      Neurosci Lett 369

      Pages: 75-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W (NPW), in the Developing Rat Stomach.

    • Author(s)
      Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M
    • Journal Title

      Regul Pept. (in press)

    • Data Source
      KAKENHI-PROJECT-18022035
  • [Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor

    • Author(s)
      Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M
    • Journal Title

      Endocrinology, (in press)

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men

    • Author(s)
      Toshinai K, Kawagoe T, Shimbara T, Tobina T, Nishida Y, Mondal MS, Yamaguchi H, Date Y, Tanaka H, Nakazato M
    • Journal Title

      Hormone and Metab. Res. (in press)

    • Data Source
      KAKENHI-PROJECT-18700555
  • [Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.

    • Author(s)
      Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T Minamino N, Nunoi H, Nakazato M
    • Journal Title

      Endocrinology, (in press)

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W (NPW), in the Developing Rat Stomach.

    • Author(s)
      Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M.
    • Journal Title

      Regul Pept. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W(NPW), in the Developing Rat Stomach.

    • Author(s)
      Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M.
    • Journal Title

      Regul Pept. (in press)

    • Data Source
      KAKENHI-PROJECT-17590660
  • [Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W (NPW), in the Developing Rat Stomach.

    • Author(s)
      Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M
    • Journal Title

      Regul Pept. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590660
  • 1.  MONDAL M・S (00398265)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  NAKAZATO Masamitsu (10180267)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 28 results
  • 3.  YAMAGUCHI Hideki (10305097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 4.  DATE Yukari (70381100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 5.  塩見 一剛 (40305082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  十枝内 厚次 (80381101)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 7.  松尾 崇 (10404427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  初 春平 (90381102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  モンダール M・S
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 26 results

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