SHIMBARA Takuya 新原琢也

Researcher Number	10398266
Affiliation (based on the past Project Information) *help	2007: 宮崎大, 医学部, 研究員 2006: UNIVERSITY OF MIYAZAKI, FACULTY OF MEDICINE, ASSISTANT PROFESSOR, 医学部, 助手 2005: 宮崎大学, 医学部, COEリサーチアソシエイト
Review Section/Research Field	Principal Investigator Applied health science Except Principal Investigator Gastroenterology / Biological Sciences
Keywords	Principal Investigator 身体運動 / 成長ホルモン / ソマトポーズ / アディポサイトカイン / 脂肪細胞 / グレリン Except Principal Investigator 高感度RIA系 / 腫瘍細胞株 / Ca^<2+>イメージング装置 / オーファン受容体 … More / ペプチドの網羅的解析 / RIA / tumor cell lines / IMACS / orphan receptor / peptidomics analysis / gut peptide / 消化管ペプチド / vgf / アルツハイマー病 / NERP / 脳アミロイド / BRI / Ca^<2+>イメージング / 摂食・エネルギー代謝調節 Less

ペプチドーム解析を応用した脳機能調節に作用する新規ペプチドの探索と機能研究
- Principal Investigator
  
  NAKAZATO Masamitsu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
エネルギー代謝調節ペプチドグレリンの脂肪組織に対する作用Principal Investigator
- Principal Investigator
  
  新原琢也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Miyazaki
Identification of novel bioactive gut peptides and clarification of feeding regulation of brain-gut axis
- Principal Investigator
  
  MONDAL M・S
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Miyazaki

All 2008 2007 2006 2005 2004 Other

All Journal Article

[Journal Article] Vagal afferent pathway does not play a major on satiety induced by intestinal fatty acid.2008
- Author(s)
  Ogawa N, Yamaguchi H, Shimbara T, Toshinai K, Kakutani M, Yonemori F, Nakazato M
- Journal Title
  
  Neurosci Lett 433
  
  Pages: 38-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Ontogeny of a new enteric peptide, neuropeptide W(NPW), in the developing rat stomach.2007
- Author(s)
  Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M
- Journal Title
  
  Regul Pept 145
  
  Pages: 141-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men2007
- Author(s)
  Toshinai T, Kawagoe T, Shimbara T, Tobina T, Nishida Y, Mondal MS, Yamaguchi H, Date Y, Tanaka H, Nakazato M
- Journal Title
  
  Horm Metab Res 39
  
  Pages: 849-851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and-22007
- Author(s)
  Yamaguchi H, Sasaki K, Satomi Y, Shimbara T, Kageyama H, Mondal MS, Toshinai K, Date Y, Gonzalez LJ, Shioda S, Takao T, Nakazato M, Minamino N
- Journal Title
  
  J Biol Chem 282
  
  Pages: 26354-26360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007
- Author(s)
  Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
- Journal Title
  
  Mech Ageing Dev 128
  
  Pages: 182-186
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007
- Author(s)
  Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
- Journal Title
  
  Mech Ageing Dev, 128
  
  Pages: 182-186
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007
- Author(s)
  Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
- Journal Title
  
  Mech Ageing Dev 128
  
  Pages: 715-721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007
- Author(s)
  Toshinai K, Mondal MS, Shimbara T, Yamaguchi H, Date Y, Kangawa K, Nakazato M
- Journal Title
  
  Mech Ageing Dev. 128(2)
  
  Pages: 182-186
- Data Source
  KAKENHI-PROJECT-18700555
[Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men2007
- Author(s)
  Toshinai K, Kawagoe T, Shimbara T, Tobina T, Nishida Y, Mondal MS, Yamaguchi H, Date Y, Tanaka H, Nakazato M
- Journal Title
  
  Horm Metab Res 39
  
  Pages: 849-851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006
- Author(s)
  Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M
- Journal Title
  
  Endocrinology 147
  
  Pages: 2306-2314
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus.2006
- Author(s)
  Date Y, Shimbara T, Koda S, Toshinai K, Ida T, Murakami N, Miyazato M, Kokame K, Ishizuka Y, Ishida Y, Kageyama H, Shioda S, Kangawa K, Nakazato M
- Journal Title
  
  Cell Metab 4
  
  Pages: 323-331
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006
- Author(s)
  Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M
- Journal Title
  
  Endocrinology 147
  
  Pages: 2306-2314
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006
- Author(s)
  Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M.
- Journal Title
  
  Endocrinology 147
  
  Pages: 2043-2050
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006
- Author(s)
  Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M.
- Journal Title
  
  Endocrinology 147
  
  Pages: 2306-2314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006
- Author(s)
  Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M
- Journal Title
  
  Endocrinology 147
  
  Pages: 2043-2050
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006
- Author(s)
  Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M
- Journal Title
  
  Endocrinology 147
  
  Pages: 2043-2050
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumonia.2006
- Author(s)
  Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS, Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M.
- Journal Title
  
  Eur Respir J 27
  
  Pages: 253-260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumonia.2006
- Author(s)
  Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS, Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M
- Journal Title
  
  Eur Respir J 27
  
  Pages: 253-260
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus.2006
- Author(s)
  Date Y, Shimbara T(contributed equally as first author), Koda S, Toshinai K, Ida T, Murakami N, Miyazato M, Kokame K, Ishizuka Y, Ishida Y, Kageyama H, Shioda S, Kangawa K, Nakazato M
- Journal Title
  
  Cell Metab. 4(4)
  
  Pages: 253-260
- Data Source
  KAKENHI-PROJECT-18700555
[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006
- Author(s)
  Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M.
- Journal Title
  
  Endocrinology, 147
  
  Pages: 2306-2314
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumon a.2006
- Author(s)
  Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS, Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M.
- Journal Title
  
  Eur Respir J, 27
  
  Pages: 253-260
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006
- Author(s)
  Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T, Minamino N, Nunoi H, Nakazato M.
- Journal Title
  
  Endocrinology, 147
  
  Pages: 2043-2050
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Identification of hBD-3 in respiratory tract and serum and its increase in pneumonia.2005
- Author(s)
  Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS.Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M
- Journal Title
  
  Eur Respir J 27
  
  Pages: 253-260
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Central administration of ghrelin preferentially enhances fat ingestion.2004
- Author(s)
  Shimbara T, Mondal MS, Kawagoe T, Toshinai K, Koda S, Yamaguchi H, Date Y, Nakazato M.
- Journal Title
  
  Neurosci Lett 369
  
  Pages: 75-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W (NPW), in the Developing Rat Stomach.
- Author(s)
  Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M
- Journal Title
  
  Regul Pept. (in press)
- Data Source
  KAKENHI-PROJECT-18022035
[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor
- Author(s)
  Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M
- Journal Title
  
  Endocrinology, (in press)
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men
- Author(s)
  Toshinai K, Kawagoe T, Shimbara T, Tobina T, Nishida Y, Mondal MS, Yamaguchi H, Date Y, Tanaka H, Nakazato M
- Journal Title
  
  Hormone and Metab. Res. (in press)
- Data Source
  KAKENHI-PROJECT-18700555
[Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.
- Author(s)
  Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y, Murakami N, Katafuchi T Minamino N, Nunoi H, Nakazato M
- Journal Title
  
  Endocrinology, (in press)
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W (NPW), in the Developing Rat Stomach.
- Author(s)
  Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M.
- Journal Title
  
  Regul Pept. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W(NPW), in the Developing Rat Stomach.
- Author(s)
  Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M.
- Journal Title
  
  Regul Pept. (in press)
- Data Source
  KAKENHI-PROJECT-17590660
[Journal Article] Ontogeny of a New Enteric Peptide, Neuropeptide W (NPW), in the Developing Rat Stomach.
- Author(s)
  Mondal MS, Yamaguchi H, Date Y, Tsuruta T, Shimbara T, Toshinai K, Shimomura Y, Mori M, Nakazato M
- Journal Title
  
  Regul Pept. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590660

1. MONDAL M・S (00398265)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NAKAZATO Masamitsu (10180267)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
3. YAMAGUCHI Hideki (10305097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
4. DATE Yukari (70381100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
5. 塩見一剛 (40305082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 十枝内厚次 (80381101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. 松尾崇 (10404427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 初春平 (90381102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. モンダール M・S

# of Collaborated Projects: 0 results

# of Collaborated Products: 26 results

SHIMBARA Takuya 新原 琢也

Research Projects

Research Products

Co-Researchers

ペプチドーム解析を応用した脳機能調節に作用する新規ペプチドの探索と機能研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エネルギー代謝調節ペプチドグレリンの脂肪組織に対する作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel bioactive gut peptides and clarification of feeding regulation of brain-gut axis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Vagal afferent pathway does not play a major on satiety induced by intestinal fatty acid.2008

Author(s)

Journal Title

Data Source

[Journal Article] Ontogeny of a new enteric peptide, neuropeptide W(NPW), in the developing rat stomach.2007

Author(s)

Journal Title

Data Source

[Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men2007

Author(s)

Journal Title

Data Source

[Journal Article] Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and-22007

Author(s)

Journal Title

Data Source

[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

Author(s)

Journal Title

Data Source

[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

Author(s)

Journal Title

Data Source

[Journal Article] Ghrelin stimulates growth hormone secretion and food intake in aged rats.2007

Author(s)

Journal Title

Data Source

[Journal Article] Acute incremental exercise decreases plasma ghrelin level in healthy men2007

Author(s)

Journal Title

Data Source

[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus.2006

Author(s)

Journal Title

Data Source

[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006

Author(s)

Journal Title

Data Source

[Journal Article] Central effects of CRSP-1 on energy homeostasis in rats.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.2006

Author(s)

Journal Title

SHIMBARA Takuya 新原琢也