Tada Hitoshi 多田均

Researcher Number	10400491
Other IDs	https://orcid.org/0000-0003-0668-9024
Affiliation (based on the past Project Information) *help	2018 – 2020: 北海道科学大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator 細胞外マトリックス / DDS / 光イメージング / 肺投与 / 早期診断 / 早期発見 / 病巣検出 / リポソーム / FRET / 肺線維芽細胞 … More / in vivo imaging / 組織透明化 / コラーゲン / 蛍光イメージング / 肺線維症 / ドラッグデリバリーシステム Less

Fluorescent Imaging of pulmonary fibrotic foci by pulmonary drug delivery systemsPrincipal Investigator
- Principal Investigator
  
  Tada Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Hokkaido University of Science

All 2020 2019 2018

All Journal Article Presentation

[Journal Article] Multiscale live imaging using Forster Resonance Energy Transfer (FRET) for evaluating the biological behavior of nanoparticles as drug carriers2020
- Author(s)
  Ishizawa K, Togami K, Tada H, Chono S
- Journal Title
  
  J.Pharm.Sci.
  
  Volume: 109 Issue: 12 Pages: 3608-3616
- DOI
  10.1016/j.xphs.2020.08.028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Aerosolized Liposomal Formulation Prevents Enhanced Drug Transfer from Fibrotic Lungs to the Systemic Circulation2020
- Author(s)
  Togami Kohei、Kurasho Kaede、Kanehira Yukimune、Tada Hitoshi、Chono Sumio
- Journal Title
  
  Current Drug Delivery
  
  Volume: 18 Issue: 7 Pages: 923-930
- DOI
  10.2174/1567201818666201229154143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066, KAKENHI-PROJECT-19K22778
[Journal Article] Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycininduced pulmonary fibrosis2020
- Author(s)
  Togami K, Maruta Y, Nanbu M, Tada H, Chono S
- Journal Title
  
  Drug Dev. Ind. Pharm.
  
  Volume: 46 Issue: 11 Pages: 1873-1880
- DOI
  10.1080/03639045.2020.1825473
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Three-dimensional imaging of pulmonary fibrotic foci at the alveolar scale using tissueclearing treatment with staining techniques of extracellular matrix2020
- Author(s)
  Togami K, Ozaki H, Yumita Y, Kitayama A, Tada H, Chono S
- Journal Title
  
  Int. J. Biomed. Imaging
  
  Volume: 2020 Pages: 8815231-8815231
- DOI
  10.1155/2020/8815231
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Evaluation of tissue-clearing techniques for intraorgan imaging of distribution of polymeric nanoparticles as drug carriers2020
- Author(s)
  Ishizawa K, Togami K, Tada H, Chono S
- Journal Title
  
  Drug Dev. Ind. Pharm.
  
  Volume: 46 Issue: 12 Pages: 2061-2069
- DOI
  10.1080/03639045.2020.1843476
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178, KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066
[Journal Article] Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer2019
- Author(s)
  Kanehira Yukimune、Togami Kohei、Ishizawa Kiyomi、Sato Shingo、Tada Hitoshi、Chono Sumio
- Journal Title
  
  Pharmaceutical Development and Technology
  
  Volume: 24 Issue: 9 Pages: 1095-1103
- DOI
  10.1080/10837450.2019.1633345
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066, KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178
[Journal Article] Evaluation of various tissue-clearing techniques for the three-dimensional visualization of liposome distribution in mouse lungs at the alveolar scale2019
- Author(s)
  Kohei Togami, Takayuki Daisho, Yuki Yumita, Anri Kitayama, Hitoshi Tada, Sumio Chono
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 562 Pages: 218-227
- DOI
  10.1016/j.ijpharm.2019.03.032
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06603, KAKENHI-PROJECT-18K12066, KAKENHI-PROJECT-19K22778, KAKENHI-PROJECT-17H02178
[Journal Article] Facile and sensitive HPLC-UV method for determination of nintedanib in rat plasma2018
- Author(s)
  Kohei Togami, Kenta Fukuda, Kotaro Yamaguchi, Hitoshi Tada, Sumio Chono
- Journal Title
  
  International Journal of Pharmacy and Pharmaceutical Science
  
  Volume: 10 Pages: 133-137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] 抗線維化薬ニンテダニブ-シクロデキストリン複合体の肺投与による肺内動態および肺線維症治療効果の改善2020
- Author(s)
  戸上紘平，小笠原安理沙，入江沙世，岩田健嗣，山口広太郎，多田均，丁野純男
- Organizer
  第36回日本DDS学会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] シクロデキストリン複合体化による抗線維化薬ニンテダニブの肺内動態および肺線維症治療効果の改善2020
- Author(s)
  戸上紘平, 岩田健嗣, 小笠原安理沙, 入江沙世, 山口広太郞, 多田均, 丁野純男
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] ヒドロキシプロピル-γ-シクロデキストリンを用いた抗線維化薬ニンテダニブ肺投与の有用性2020
- Author(s)
  戸上紘平、小笠原安理沙、入江沙世、岩田健嗣、山口広太郎、多田均、丁野純男
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] Real-time FRET imagingによるドラッグキャリアの体内動態の可視化2019
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] Efficient delivery to fibrotic regions of liposomes modified with fibroblasts and collagen targeting for treatment in idiopathic pulmonary fibrosis2019
- Author(s)
  Kohei Togami, Hirotsugu Ishii, Ryota Abe, Hitoshi Tada, Sumio Chono
- Organizer
  CRS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] 肺線維症治療を指向したリポソームの肺線維芽細胞への集積性およびcollagen Iへの付着性に関する検討2019
- Author(s)
  戸上紘平、石井大嗣、阿部亮太、多田均、丁野純男
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] Multiscale live-imaging using F?rster resonance energy transfer to evaluate the distribution of nanoparticles for drug delivery2019
- Author(s)
  Kiyomi Ishizawa, Kohei Togami, Hitoshi Tada, Sumio Chono
- Organizer
  CRS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] ドラッグキャリアの体内動態を可視化するreal-time FRET imaging2019
- Author(s)
  石澤清心, 戸上紘平, 多田均, 丁野純男
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] ドラッグキャリアに用いるナノ粒子と内封薬物の体内分布評価のためのFRET現象を応用したmulti-scale imaging2018
- Author(s)
  石澤清心、戸上紘平、多田均、丁野純男
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] 肺線維症発症時における肺投与型リポソームの肺内滞留性に関する検討2018
- Author(s)
  藏所楓、兼平幸宗、多田均、丁野純男、戸上紘平
- Organizer
  日本薬学会北海道支部第145例会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] FRET現象を応用したmulti-scale imagingによるドラッグキャリアと内封薬物の体内分布評価法の確立2018
- Author(s)
  石澤清心、戸上紘平、多田均、丁野純男
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] Multi-scale imaging using Forster resonance energy transfer for evaluating drug carrier distribution2018
- Author(s)
  Kiyomi Ishizawa, Kohei Togami, Hitoshi Tada, Sumio Chono
- Organizer
  AAPS 2018 PHARMSCI 360
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12066
[Presentation] FRET現象を応用したmulti-scale imagingによるDDSの機能評価法の確立2018
- Author(s)
  石澤清心、戸上紘平、多田均、丁野純男
- Organizer
  日本薬学会北海道支部第145例会
- Data Source
  KAKENHI-PROJECT-18K12066

1. 戸上紘平 (20582357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
2. CHONO Sumio

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Tada Hitoshi 多田 均

Research Projects

Research Products

Co-Researchers

Fluorescent Imaging of pulmonary fibrotic foci by pulmonary drug delivery systemsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Multiscale live imaging using Forster Resonance Energy Transfer (FRET) for evaluating the biological behavior of nanoparticles as drug carriers2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aerosolized Liposomal Formulation Prevents Enhanced Drug Transfer from Fibrotic Lungs to the Systemic Circulation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycininduced pulmonary fibrosis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three-dimensional imaging of pulmonary fibrotic foci at the alveolar scale using tissueclearing treatment with staining techniques of extracellular matrix2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of tissue-clearing techniques for intraorgan imaging of distribution of polymeric nanoparticles as drug carriers2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of various tissue-clearing techniques for the three-dimensional visualization of liposome distribution in mouse lungs at the alveolar scale2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Facile and sensitive HPLC-UV method for determination of nintedanib in rat plasma2018

Author(s)

Journal Title

Data Source

[Presentation] 抗線維化薬ニンテダニブ-シクロデキストリン複合体の肺投与による肺内動態および肺線維症治療効果の改善2020

Author(s)

Organizer

Data Source

[Presentation] シクロデキストリン複合体化による抗線維化薬ニンテダニブの肺内動態および肺線維症治療効果の改善2020

Author(s)

Organizer

Data Source

[Presentation] ヒドロキシプロピル-γ-シクロデキストリンを用いた抗線維化薬ニンテダニブ肺投与の有用性2020

Author(s)

Organizer

Data Source

[Presentation] Real-time FRET imagingによるドラッグキャリアの体内動態の可視化2019

Author(s)

Organizer

Data Source

[Presentation] Efficient delivery to fibrotic regions of liposomes modified with fibroblasts and collagen targeting for treatment in idiopathic pulmonary fibrosis2019

Author(s)

Organizer

Data Source

[Presentation] 肺線維症治療を指向したリポソームの肺線維芽細胞への集積性およびcollagen Iへの付着性に関する検討2019

Author(s)

Organizer

Data Source

[Presentation] Multiscale live-imaging using F?rster resonance energy transfer to evaluate the distribution of nanoparticles for drug delivery2019

Author(s)

Organizer

Data Source

[Presentation] ドラッグキャリアの体内動態を可視化するreal-time FRET imaging2019

Author(s)

Organizer

Tada Hitoshi 多田均