HIRASAWA Takae 平澤孝枝

… Alternative Names

Hirasawa Takae 平澤孝枝

奥野孝枝オクノタカエ

平澤孝枝ヒラサワタカエ

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Researcher Number	10402083
Other IDs
Affiliation (Current)	2025: 帝京大学, 理工学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 帝京大学, 理工学部, 准教授 2019 – 2023: 帝京大学, 理工学部, 准教授 2014 – 2016: 帝京大学, 理工学部, 講師 2011 – 2013: 山梨大学, 医学工学総合研究部, 助教 2010: University of Yamanashi, 大学院・医学工学研究部, 助教 … More 2008 – 2010: University of Yamanashi, 大学院・医学工学総合研究部, 助教 2008: University of Yamanashi, 大学院医学工学総合研究部, 助教 2006 – 2007: 山梨大, 医学工学総合研究部, 助手 2004: 国立精神・神経センター, 代謝研究部, 研究員 2003: 国立精神・神経センター, 代謝研究部, 流動研究員 Less
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 42030:Animal life science-related / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 母子分離 / エピジェネティクス / ミクログリア / ストレス / 母子分離ストレス / 脳機能 / 脳 / 発現制御 / ミトコンドリア / マイトファジー … More / 発達遅滞 / 精神ストレス / 生後環境 / シナプス / 免疫制御 / 発達障害 / グルココルチコイド / 脳・神経 / 神経科学 / 自閉症 / 抑制性 / 小児性てんかん / 遺伝子発現調節 / てんかん … More Except Principal Investigator グルタミン酸 / カルシウム / NMDA受容体 / ATP受容体 / ニューロン / 可視化 / トランスジェニックマウス / EGFP / Iba1 / マクロファージ / 膜ラッフル / 遊走能 / P2X4受容体 / P2Y12受容体 / ケモタキシス / ATP / ミクログリア Less

ニホンウナギのエピジェネティクス制御に起因する性分化システムの解明Principal Investigator
- Principal Investigator
  
  平澤孝枝
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Teikyo University
the mechanism of microglial polarity switching by stress-induced mitophagy abnormality.Principal Investigator
- Principal Investigator
  
  平澤孝枝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Teikyo University
an new approach the pathogenesis of mental retardation from the abnormality of microglia by postnatal mental stress.Principal Investigator
- Principal Investigator
  
  Hirasawa Takae
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Teikyo University
Elucidation of construction abnormality of brain cytokine network caused by juvenile stressPrincipal Investigator
- Principal Investigator
  
  HIRASAWA Takae
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Teikyo University
The epigenetic regulation of brain development by maternal stressPrincipal Investigator
- Principal Investigator
  
  HIRASAWA Takae
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
The epigenetic mechanism of synaptic molecules in autismPrincipal Investigator
- Principal Investigator
  
  HIRASAWA Takae
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
The epigenetic regulation in infantile epilepsyPrincipal Investigator
- Principal Investigator
  
  HIRASAWA Takae
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
ATPを介したニューロン・ミクログリア相互作用の分子基盤
- Principal Investigator
  
  高坂新一
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Center of Neurology and Psychiatry

[Book] Chapter : Epigenetic modifications : genetic basis of environmental stress response. In "DNA Replication /Book 12011
- Author(s)
  Kubota T, Miyake K, Hirasawa T
- Publisher
  Intech (Open Access Publisher)(ISBN 978-953-307-259-3)
- Data Source
  KAKENHI-PROJECT-23591491
[Book] BRAIN and NERVE Vol.59 No.7 ミクログリア可視化トランスジェニックマウスの作製2007
- Author(s)
  平澤孝枝、高坂新一
- Total Pages
  10
- Publisher
  (株)医学書院
- Data Source
  KAKENHI-PROJECT-15082213
[Book] Epigenetics in autism and other neurodevelopmental diseases. Molecular Mechanism of Neurodegenerative diseases (Ahmad S.編)
- Author(s)
  Miyake K, Hirasawa T, Koide T, Kubota T.
- Publisher
  Landes Bioscince/Springer,印刷中
- Data Source
  KAKENHI-PROJECT-21790974
[Journal Article] Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra syndrome.2021
- Author(s)
  Yamada A*, Hirasawa T*, Nishimura K, Shimura C, Kogo N, Fukuda K, Kato M, Yokomori M, Hayashi T, Umeda M, Yoshimura M, Iwakura Y, Nikaido I, Itohara S, Shinkai Y.
- Journal Title
  
  iScience
  
  Volume: 24（7） Pages: 102741-102741
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08353
[Journal Article] 胎児期・幼若期ストレスに起因する生後の脳機能発達とミクログリア2021
- Author(s)
  平澤孝枝
- Journal Title
  
  ストレス科学
  
  Volume: 36（1） Pages: 22-34
- Data Source
  KAKENHI-PROJECT-19K08353
[Journal Article] Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny2017
- Author(s)
  Furuse T, Miyake K, Kohda T, Kaneda H, Hirasawa T, Yamada I, Kushida T, Kashimura M, Kobayashi K, Ishino F, Kubota T, Wakana S.
- Journal Title
  
  Genes & Nutrition
  
  Volume: 12 Issue: 1 Pages: 1-1
- DOI
  10.1186/s12263-016-0550-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-26430098, KAKENHI-PROJECT-26461521, KAKENHI-PROJECT-15K09592, KAKENHI-PROJECT-26430087, KAKENHI-PUBLICLY-15H01468, KAKENHI-PROJECT-17K07498
[Journal Article] Long-term imipramine treatment increases N-methyl-d-aspartate receptor activity and expression via epigenetic mechanisms2015
- Author(s)
  Nghia NA, Hirasawa T, Kasai H, Obata C, Moriishi K, Mochizuki K, Koizumi S, Kubota T.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 752C Pages: 69-77
- DOI
  10.1016/j.ejphar.2015.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25117003, KAKENHI-PROJECT-25670622, KAKENHI-PROJECT-26461521, KAKENHI-PROJECT-15K15388
[Journal Article] Maternal restraint stress during pregnancy in mice induces 11β-HSD1-associated metabolic changes in the livers of the offspring.2015
- Author(s)
  Maeyama H, Hirasawa T, Tahara Y, Obata C, Kasai H, Moriishi K, Mochizuki K, Kubota T.
- Journal Title
  
  J Dev Orig Health Dis.
  
  Volume: 6(2) Issue: 2 Pages: 105-114
- DOI
  10.1017/s2040174415000100
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461521, KAKENHI-PROJECT-15K15388
[Journal Article] Comparison of genomic and epigenomic expression in monozygotic twins discordant for Rett syndrome2013
- Author(s)
  Miyake K, Yang C, Minakuchi Y, Ohori K, Soutome M, Hirasawa T, Kazuki Y, Adachi N, Suzuki S, Itoh M, Goto Y, Andoh T, Kurosawa H, Akamatsu W, Oyama M, Okano H, Oshimura M, Sasaki M, Toyoda A, Kubota T
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 6 Pages: e66729-e66729
- DOI
  10.1371/journal.pone.0066729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240062, KAKENHI-PROJECT-23390272, KAKENHI-PROJECT-23591491, KAKENHI-PROJECT-25670473, KAKENHI-PROJECT-25860852
[Journal Article] Epigenetics in Neurodevelopmental and Mental Disorders2013
- Author(s)
  Kubota T, Miyake K, Hirasawa T
- Journal Title
  
  Med Epigenet
  
  Volume: 1 Issue: 1 Pages: 52-59
- DOI
  10.1159/000354718
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] The role of epigenetics in Rett syndrome2013
- Author(s)
  Kubota T, Miyake K, Hirasawa T
- Journal Title
  
  Epigenomics
  
  Volume: 5(5) Pages: 1-10
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] Epigenetic understanding of gene-environment interactions in psychiatric disorders: a new concept of clinical genetics.2012
- Author(s)
  Kubota T, et al.
- Journal Title
  
  Clin Epigenetics
  
  Volume: 4 Issue: 1 Pages: 1-1
- DOI
  10.1186/1868-7083-4-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390272, KAKENHI-PROJECT-23591491, KAKENHI-PROJECT-23659519, KAKENHI-PROJECT-23791156, KAKENHI-PROJECT-24659437
[Journal Article] Epigenetics in autism and other neurodevelopmental diseases.2012
- Author(s)
  Miyake K, Hirasawa T, Koide T, Kubota T.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 724 Pages: 91-98
- DOI
  10.1007/978-1-4614-0653-2_7
- ISBN
  9781461406525, 9781461406532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591491, KAKENHI-PROJECT-23791156
[Journal Article] Epigenetics in autism and other neurodevelopmental diseases2012
- Author(s)
  Miyake K, Hirasawa T, Koide T, Kubota T
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 724 Pages: 91-98
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] 小児発達障害のエピジェネティクス2011
- Author(s)
  平澤孝枝
- Journal Title
  
  チャイルドヘルス
  
  Volume: 15(3) Pages: 173-176
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome.2011
- Author(s)
  Hirasawa T
- Journal Title
  
  BMC Neuroscience
  
  Volume: 12 Pages: 81-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] 自閉症とエピジェネティクス2011
- Author(s)
  平澤孝枝
- Journal Title
  
  分子精神医学
  
  Volume: 11(4) Pages: 289-294
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] 自閉症とエピジェネティクス2011
- Author(s)
  平澤孝枝, 久保田健夫
- Journal Title
  
  分子精神医学
  
  Volume: 11(10) Pages: 27-32
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues : implication for pathogenesis of Rett syndrome2011
- Author(s)
  Miyake K#, Hirasawa T#, Soutome M, Itoh M, Goto Y, Endoh K, Takahashi K, Kudo S, Nakawaga T, Yokoi S, Taira T, Inazawa J, Kubota T(# Equal contribution)
- Journal Title
  
  BMC Neurosci
  
  Volume: 12(81) Issue: 1
- DOI
  10.1186/1471-2202-12-81
- Data Source
  KAKENHI-PROJECT-23591491
[Journal Article] Inhibition of NMDA receptoror activity resulted in aberrant neuronal migration caused by delayed morphological development in the mouse neocortex.2010
- Author(s)
  Uchino S, Hirasawa T, Tabata H, Gonda Y, Waga C, Ondo Y, Nakajima K, Kohsaka S.(#Equal contribution)
- Journal Title
  
  Neurosciece 169(2)
  
  Pages: 609-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790974
[Journal Article] Novel etiological and therapeutic strategies for neurodiseases : epigenetic understanding of gene-environment interactions.2010
- Author(s)
  Kubota T, Miyake K, Hirasawa T, Nagai K, Koide T.
- Journal Title
  
  J Pharmacol Sci 113
  
  Pages: 3-8
- NAID
  10027744756
- Data Source
  KAKENHI-PROJECT-21790974
[Journal Article] Transthyretin accelerates vascular Abeta deposition in a mouse model of alzheimer's disease2009
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Hagiwara Y, Shogi M, Maeda S
- Journal Title
  
  Brain Pathol 19(1)
  
  Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790707
[Journal Article] Transthyretin A ccelerates Vascular Abeta Deposition in a Mouse Model of Alzheimer's disease.2009
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Hagiwara Y, Shogi M, Maeda S.
- Journal Title
  
  Brain Pathol 19(1)
  
  Pages: 48-57
- Data Source
  KAKENHI-PROJECT-21790974
[Journal Article] Augmentation of plysialic acid by valproic acid in early postnatal mouse hippocampus and primary cultured hippocampal neurons2008
- Author(s)
  Natori T, Kodaira F, Hirasawa T, Gao YY, Nagai K
- Journal Title
  
  J Biosci Bioengineering 105(29)
  
  Pages: 164-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790707
[Journal Article] Transthyretin Accelerates Vascular Abeta Deposition in a Mouse Model of Alzheimer's Disease2008
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Hagiwara Y, Shogi M, Maeda S.
- Journal Title
  
  Brain Pathol 19(1)
  
  Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790707
[Journal Article] Augmentation of plysialic acid by valproic acid in early postnatal mouse hippocampus and primary cultured hippocampal neurons2008
- Author(s)
  Natori T, Kodaira F, Hirasawa T, Gao YY, Nagai K.
- Journal Title
  
  J Biosci Bioengineering 105(29)
  
  Pages: 164-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790707
[Journal Article] ミクログリア可視化トランスジェニックマウスの作製2007
- Author(s)
  平澤孝枝, 高坂新一
- Journal Title
  
  BRAIN AND NERVE 59(7)
  
  Pages: 763-772
- Data Source
  KAKENHI-PROJECT-18790707
[Journal Article] Direct interaction of PDZ domain-containing synaptic molecule Shank3 with GluR1 AMPA receptor J2006
- Author(s)
  Uchino S, Wada H, Honda S, Nakamura Y, Ondo Y,Uchiyama T, Tsutsumi M, Suzuki E, Hirasawa T, Kohsaka S
- Journal Title
  
  Neurochem 97(4)
  
  Pages: 1203-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790707
[Journal Article] 知的発達障害とエピジェネティクスの分子遺伝学2006
- Author(s)
  平澤孝枝, 久保田健夫
- Journal Title
  
  神経研究の進歩 50(5)
  
  Pages: 770-779
- Data Source
  KAKENHI-PROJECT-18790707
[Journal Article] Receptor related to tyrosine kinase RYK regulates cell migration during cortical development.2005
- Author(s)
  Kamitori, K., Tanaka, M., Okuno-Hirasawa, T., Kohsaka, S.
- Journal Title
  
  BBRC 330
  
  Pages: 446-453
- Data Source
  KAKENHI-PROJECT-15082213
[Journal Article] Visualization of microglia in living tissues by using Iba1-EGFP transgenic mice.2005
- Author(s)
  Hirasawa, T., Ohsawa, K., Imai, Y., Ondo, Y., Akazawa, C., Uchino, S., Kohsaka, S.
- Journal Title
  
  J.Neurosci.Res. 81
  
  Pages: 357-362
- NAID
  40015561882
- Data Source
  KAKENHI-PROJECT-15082213
[Journal Article] Visualization of microglia in living tissues by using Iba1-EGFP transgenic mice.2005
- Author(s)
  Hirasawa, T., Ohsawa, K., Imai, Y., Ondo, Y., Uchino, S.
- Journal Title
  
  J.Neurosci.Res. (in press)
- NAID
  40015561882
- Data Source
  KAKENHI-PROJECT-15082213
[Presentation] 環境応答によるバイオダイバーシティ　－遺伝子, 種, 生態－2022
- Author(s)
  平澤孝枝
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08353
[Presentation] 環境応答によるバイオダイバーシティ　－遺伝子, 種, 生態－2022
- Author(s)
  平澤孝枝
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K07378
[Presentation] Temperature-dependent sexual differentiation mechanism in Japanese eel2021
- Author(s)
  滝沢零士、平澤孝枝、吉田宰、原秀磨、夘月祥太
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K08353
[Presentation] 幼若期ストレスにおける脳内ミクログリア細胞の動態とストレス耐性2020
- Author(s)
  平澤孝枝
- Organizer
  第36回日本ストレス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08353
[Presentation] 骨格筋神経における非活動性侵害受容器の組織学的発現解析2020
- Author(s)
  菊地貴矢, 太田大樹, 平澤孝枝, 田口徹
- Organizer
  第20回新潟医療福祉学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08353
[Presentation] Klllefstra症候群モデルマウスを用いた神経症状発症機構の解明2019
- Author(s)
  山田亜夕美、西村佳也子、志村知古、平澤孝枝、眞貝洋一
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08353
[Presentation] Proteasome Activator PA28 gamma regulates neuronal function of cerebellar Purkinje cells.2016
- Author(s)
  中村和純, 天笠太一, 鶴岡直人, 葛西宏威, 森石恆司, 平澤孝枝
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-26461521
[Presentation] Synaptic dysfunction in the Glp Knockout mouse model of Kllefstra syndrome.2016
- Author(s)
  Takae Hirasawa, Ayumi Yamada, Madoka Kato, Yoichi Shinkai, Takeo Kubota.
- Organizer
  第39回日本神経科学学会
- Place of Presentation
  横浜（パシフィコ横浜）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461521
[Presentation] 幼若期ストレスにおけるストレス耐性機能の獲得とミクログリア2015
- Author(s)
  平澤孝枝
- Organizer
  BMB2015第38回日本分子生物学会/第88回日本生化学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26461521
[Presentation] The effects of maternal malnutrition in utero on gene expression, genomic methylation and behavioral phenotypes in mouse.2015
- Author(s)
  Tamio Furuse, Takashi Kohda, Kunio Miyake, Takae Hirasawa, Tomoko Kushida
- Organizer
  第38回日本神経科学学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26461521
[Presentation] 胎児期ストレスとエピジェネィクス変化2014
- Author(s)
  平澤孝枝
- Organizer
  第4回日本DOHaD研究会学術集会
- Place of Presentation
  国立成育医療センター（東京世田谷区）
- Year and Date
  2014-07-26
- Invited
- Data Source
  KAKENHI-PROJECT-26461521
[Presentation] Long-term imipramine treatment up-regulates NMDA receptors by epigenetic mechanisms in mouse cortical cultured neurons.2014
- Author(s)
  Nghia Nguyen, Takae Hirasawa, Hirotake Kasai, Chie Obata, Kohji Moriishi, Kazuki Mochizuki, Takeo Kubota.
- Organizer
  第37 回日本神経科学学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26461521
[Presentation] Mental stress during pregnancy affects to the lipid metabolism mediated by activating the 11be-ta hydroxysteroid dehydrogenase type1 in the liver of the offspring mouse.2013
- Author(s)
  Hiroki Maeyama, Yuriko Tahara, Chie Obata, Kazuki Motizuki, Takae Hirasawa and Takeo Kubota
- Organizer
  8th World Congress on Developmental Origins of Health and Disease
- Place of Presentation
  シンガポール（シンガポール、SUNTEC)
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 妊婦の低栄養と胎児のエピジェネティクス変化2013
- Author(s)
  久保田健夫, 平澤孝枝
- Organizer
  第35回日本臨床栄養学会
- Place of Presentation
  京都
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 妊娠期母体精神ストレスに起因する11β-HSD1発現上昇と肝脂質代謝異常2013
- Author(s)
  前山弘樹・田原佑里子・小幡千枝・望月和樹・平澤孝枝・久保田健夫
- Organizer
  第2回日本DOHaD研究会
- Place of Presentation
  東京
- Year and Date
  2013-06-09
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 妊娠期母体精神ストレスに起因する11β-HSD1発現上昇と肝脂質代謝異常2013
- Author(s)
  前山弘樹田原佑里子小幡千枝望月和樹平澤孝枝久保田健夫
- Organizer
  第2回日本DOHaD研究会
- Place of Presentation
  東京(厚生労働省戸山研究庁舎）
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] A new evidence of the effect of imipramine for NMDA receptors; there are two opposite effects of imipramine for neurotransmitters2013
- Author(s)
  Nguyen An Nghia, Takae Hirasawa, Schuichi Koizumi, Takeo Kubota
- Organizer
  Neuro2013(第36回日本神経科学学会)
- Place of Presentation
  神戸
- Year and Date
  2013-07-22
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] A new evidence of the effect of imipramine for NMDA receptors; there are two opposite effects of imipramine for neurotransmitters.2013
- Author(s)
  24. Nguyen An Nghia, Takae Hirasawa, Schuichi Koizumi, Takeo Kubota.
- Organizer
  Neuro2013 (第36 回日本神経科学学会)
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 動物モデルからみた発達障害の発症病態―環境ストレスと脳機能―2012
- Author(s)
  平澤孝枝
- Organizer
  第54回日本小児神経学会総会
- Place of Presentation
  ロイトン札幌, 北海道
- Invited
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 母子分離ストレスによるマウス脳海馬領域グルココルチコイド受容体の発現変化2012
- Author(s)
  平澤孝枝・石田哲史・田原佑里子・三宅邦夫・久保田健夫
- Organizer
  第6回日本エピジェネティクス研究会
- Place of Presentation
  東京
- Year and Date
  2012-05-14
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 動物モデルからみた発達障害の発症病態―環境ストレスと脳機能2012
- Author(s)
  平澤孝枝
- Organizer
  第54回日本小児神経学会総会
- Place of Presentation
  北海道
- Year and Date
  2012-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 幼若期、胎生期の環境変化によって惹起される生活習慣病に関わる遺伝子発現調節機構の解明2012
- Author(s)
  平澤孝枝
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡, 福岡
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 母子分離ストレスによるマウス脳海馬領域グルココルチコイド受容体の発現変化2012
- Author(s)
  平澤孝枝
- Organizer
  第6回日本エピジェネティクス研究会
- Place of Presentation
  学術総合センター, 東京
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] 幼若期、胎生期の環境変化によって惹起される生活習慣病に関わる遺伝子発現調節機構の解明2012
- Author(s)
  平澤孝枝・田原佑里子・石田哲史・小幡千枝・久保田健夫
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] corticosterone facilitates the synchronized calcium oscillation in hippocompal neurons.2011
- Author(s)
  T Hirasawa
- Organizer
  23th Biennial Meeting, International society for Neurochemistry
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] The role of MeCP2 in neurodevelopmental disorder2011
- Author(s)
  T. Hirasawa, K. Miyake, T. Kubota
- Organizer
  Neuro2011
- Place of Presentation
  Yokohama
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] Corticosterone facilitates the synchronized calcium oscillation in hippocampal neurons2011
- Author(s)
  T. Hirasawa, A Endo, K. Miyake, S. Koizumi, T. Kubota
- Organizer
  23th Biennial Meeting, International Society for Neurochemistry jointly with the European Society for Neurochemistry
- Place of Presentation
  Athens, Greece
- Year and Date
  2011-08-28
- Data Source
  KAKENHI-PROJECT-23591491
[Presentation] ストレスによって惹起される脳内の遺伝学的・非遺伝学的発現変化2010
- Author(s)
  平澤孝枝、遠藤彰、三宅邦夫、久保田健夫
- Organizer
  第82回日本遺伝学会
- Place of Presentation
  北海道
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21790974
[Presentation] Corticosterone facilitates the glutamate receptor-dependent synchronized calcium oscillation in hippocampal neurons.2010
- Author(s)
  Endo A, Hirasawa T, Miyake K, Kubota T.
- Organizer
  第33回日本神経科学学会
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21790974
[Presentation] ストレスによって惹起される脳内の遺伝学的・非遺伝学的発現変化2010
- Author(s)
  平澤孝枝
- Organizer
  第82回日本遺伝学会
- Place of Presentation
  北海道大学(北海道:札幌)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21790974
[Presentation] レット症候群責任蛋白質MeCP2の新規標的遺伝子の探索2010
- Author(s)
  三宅邦夫・平澤孝枝・五月女雅樹・遠藤和志・久保田健夫・平敬宏・横井左奈・井本逸勢・稲澤譲治
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21790974
[Presentation] レット症候群責任蛋白質MeCP2の標的分子の神経機能2009
- Author(s)
  平澤孝枝
- Organizer
  第4回メチレーションと小児神経学研究会
- Place of Presentation
  東京(本郷)
- Year and Date
  2009-08-23
- Data Source
  KAKENHI-PROJECT-21790974
[Presentation] レット症候群責任蛋白質MeCP2の標的分子の神経機能2009
- Author(s)
  平澤孝枝, 三宅邦夫、久保田健夫
- Organizer
  第4回メチレーションと小児神経学研究会
- Place of Presentation
  東京
- Year and Date
  2009-08-23
- Data Source
  KAKENHI-PROJECT-21790974
[Presentation] NMDA receptors participate in neuronal migration in the early stage of mouse cortical development2006
- Author(s)
  Takae Hirasawa, Hidenori Tabata, Kazunori Nakajima, Takeo Kubota, Shigeo Uchino, Shinichi Kohsaka
- Organizer
  第49回日本神経化学学会
- Place of Presentation
  名古屋
- Year and Date
  2006-09-13
- Data Source
  KAKENHI-PROJECT-18790707

1. 内野茂夫 (30392434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. KUBOTA Takeo (70293511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
3. 高坂新一 (50112686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 大澤圭子 (40392435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 権田裕子 (60424181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 和賀央子 (80462795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 入野康宏 (10415565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 橋本学 (20415566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中川竜介 (10360603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 葛西宏威 (20324189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 神鳥和代

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小泉修一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 若菜茂晴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRASAWA Takae 平澤 孝枝

Hirasawa Takae 平澤 孝枝

奥野 孝枝 オクノ タカエ

平澤 孝枝 ヒラサワ タカエ

Research Projects

Research Products

Co-Researchers

ニホンウナギのエピジェネティクス制御に起因する性分化システムの解明Principal Investigator

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the mechanism of microglial polarity switching by stress-induced mitophagy abnormality.Principal Investigator

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an new approach the pathogenesis of mental retardation from the abnormality of microglia by postnatal mental stress.Principal Investigator

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Elucidation of construction abnormality of brain cytokine network caused by juvenile stressPrincipal Investigator

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The epigenetic regulation of brain development by maternal stressPrincipal Investigator

Principal Investigator

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The epigenetic mechanism of synaptic molecules in autismPrincipal Investigator

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The epigenetic regulation in infantile epilepsyPrincipal Investigator

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ATPを介したニューロン・ミクログリア相互作用の分子基盤

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[Book] Chapter : Epigenetic modifications : genetic basis of environmental stress response. In "DNA Replication /Book 12011

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Data Source

[Book] BRAIN and NERVE Vol.59 No.7 ミクログリア可視化トランスジェニックマウスの作製2007

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Total Pages

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Data Source

[Book] Epigenetics in autism and other neurodevelopmental diseases. Molecular Mechanism of Neurodegenerative diseases (Ahmad S.編)

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Publisher

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[Journal Article] Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra syndrome.2021

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Data Source

[Journal Article] 胎児期・幼若期ストレスに起因する生後の脳機能発達とミクログリア2021

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Journal Title

Data Source

[Journal Article] Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny2017

Author(s)

Journal Title

DOI

HIRASAWA Takae 平澤孝枝

Hirasawa Takae 平澤孝枝

奥野孝枝オクノタカエ

平澤孝枝ヒラサワタカエ