Uchida Shusaku 内田周作

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UCHIDA Shusaku 内田周作

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Researcher Number	10403669
Other IDs
Affiliation (Current)	2022: 京都大学, 医学研究科, 特定准教授
Affiliation (based on the past Project Information) *help	2018 – 2022: 京都大学, 医学研究科, 特定准教授 2013 – 2018: 山口大学, 医学部附属病院, 講師 2011: Yamaguchi University, 医学(系)研究科(研究院), 助教 2007 – 2010: Yamaguchi University, 大学院・医学系研究科, 助教 2006: 山口大学, 大学院・医学系研究科, 助手 2006: Yamaguchi University, Graduate School of Medicine, Research Associate, 大学院医学系研究科, 助手 2005: Yamaguchi University, Faculty of Medicine, Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator Psychiatric science / Biological Sciences / Basic Section 52030:Psychiatry-related / Complex systems / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields Except Principal Investigator Psychiatric science
Keywords	Principal Investigator うつ病 / ストレス / エピジェネティクス / レジリエンス / 気分障害 / 選択的スプライシング / ヒストン脱アセチル化酵素 / 個体差 / 性差 / グルココルチコイド受容体 … More / 大うつ病 / 双極性障害 / 遺伝子発現制御 / SRタンパク質ファミリー / 定量的リアルタイムPCR法 / 遺伝子発現 / 撰択的スプライシング / グリア細胞由来神経栄養因子 / 神経新生 / 海馬 / エピゲノム / ストレス脆弱性 / 個性 / シナプス / 遺伝環境相互作用 / 神経回路 / 分子複合体 / 運動 / 運動トレーニング … More Except Principal Investigator 気分障害 / うつ病 / ストレス脆弱性 / 神経可塑性 / 遺伝子発現 / 双極性障害 / ストレス / neural plasticity / spine / 選択的スプライシング / 薬物治療 / リアルタイムPCR法 / モデル動物 / 神経新生 / グレリン / MRI / レプチン / 前頭葉機能 / 躁うつ病 / 神経画像 / 脳体積 / 白質走行 / 遺伝子 / 脳画像 / セロトニン / Wister Kyotoラット / セロトニン神経 / Wistarラット / Wistar Kyotoラット / depression / stress / serotonin / Wistar-Kyoto rat / うつ病モデル / 神経樹状突起 / 海馬 / 扁桃体 / Fischer344ラット / Golgi染色 / stress-vulnerability / animal model for depression / neural dendrite / hippocampus / amygdala / エピジェネティクス / うつ / 神経ネットワーク / HDAC / CaMKII / 糖鎖 / バイオマーカー / Glycosylation / Depression Less

心の健康増進をめざしたストレス感受性の生物学的基盤の解明Principal Investigator
- Principal Investigator
  
  内田周作
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto University
細胞内分子複合体の多様性から紐解くストレス感受性の個体差構築のメカニズムPrincipal Investigator
- Principal Investigator
  
  内田周作
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
運動によるストレスレジリエンス獲得の分子・神経メカニズム解明Principal Investigator
- Principal Investigator
  
  内田周作
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kyoto University
ストレス感受性の個性創発の分子神経基盤解析Principal Investigator
- Principal Investigator
  
  内田周作
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
ストレス感受性制御を司る脳内メカニズムの構成的理解Principal Investigator
- Principal Investigator
  
  内田周作
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecula and neral mechanisms of individual- and -sex differences in behavioral resposne to stressPrincipal Investigator
- Principal Investigator
  
  Uchida Shusaku
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kyoto University
Identification of glycoproteins as markers of depression
- Principal Investigator
  
  YAMAGATA Hirotaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Elucidating molecular mechanisms underlying stress vulnerabilityPrincipal Investigator
- Principal Investigator
  
  UCHIDA Shusaku
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Molecular and neural mechanisms of depression
- Principal Investigator
  
  WATANABE Yoshifumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Disrupted cortico-limbic network and molecular mechanism in bipolar disorder
- Principal Investigator
  
  MATSUO Koji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
うつモデルマウスにおけるエピジェネティックな遺伝子発現調節異常の検討Principal Investigator
- Principal Investigator
  
  内田周作
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Neural correlates of plasma acylated ghrelin level in individuals with mood disorders
- Principal Investigator
  
  MATSUO Koji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
ストレス脆弱性モデル動物における神経形態学的変化と神経可塑性異常の検討
- Principal Investigator
  
  渡辺義文
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Role of splicing factors in the pathogenesis of mood disordersPrincipal Investigator
- Principal Investigator
  
  UCHIDA Shusaku
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Role of alternative splicing in the pathophysiology of mood disorders
- Principal Investigator
  
  EGASHIRA Kazuteru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
気分障害におけるグルココルチコイド受容体遺伝子の選択的スプライシング異常の検討Principal Investigator
- Principal Investigator
  
  内田周作
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Study for stress-induced morphological alterations of neural dendrites in Fisher344 rats, an animal model for stress-vulnerability
- Principal Investigator
  
  WATANABE Yoshifumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Serotonergic neuronal plasticity in the depression model animal
- Principal Investigator
  
  SUETSUGI Masatomo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University

[Journal Article] Antidepressant Response and Stress Resilience Are Promoted by CART Peptides in GABAergic Neurons of the Anterior Cingulate Cortex2022
- Author(s)
  Funayama Yuki、Li Haiyan、Ishimori Erina、Kawatake-Kuno Ayako、Inaba Hiromichi、Yamagata Hirotaka、Seki Tomoe、Nakagawa Shin、Watanabe Yoshifumi、Murai Toshiya、Oishi Naoya、Uchida Shusaku
- Journal Title
  
  Biological Psychiatry Global Open Science
  
  Volume: ー
- DOI
  10.1016/j.bpsgos.2021.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00198, KAKENHI-PROJECT-21K19707, KAKENHI-PROJECT-21K15711
[Journal Article] Experience-Regulated Neuronal Signaling in Maternal Behavior2022
- Author(s)
  Fuentes Ileana、Morishita Yoshikazu、Gonzalez-Salinas Sofia、Champagne Frances A.、Uchida Shusaku、Shumyatsky Gleb P.
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 15
- DOI
  10.3389/fnmol.2022.844295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00198, KAKENHI-PROJECT-21K19707
[Journal Article] The Molecular Basis of Depression: Implications of Sex-Related Differences in Epigenetic Regulation2021
- Author(s)
  Kawatake-Kuno Ayako、Murai Toshiya、Uchida Shusaku
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 14
- DOI
  10.3389/fnmol.2021.708004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00198, KAKENHI-PROJECT-21K19707
[Journal Article] Characterization of the signature of peripheral innate immunity in women with later-life major depressive disorder2021
- Author(s)
  Miyata S, Yamagata H, Matsuo K, Uchida S, Harada K, Fujihara K, Yanagawa Y, Watanabe Y, Mikuni M, Nakagawa S, Fukuda M
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 87 Pages: 831-839
- DOI
  10.1016/j.bbi.2020.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04905, KAKENHI-PUBLICLY-19H05214, KAKENHI-PROJECT-18H02750, KAKENHI-PROJECT-20H03605
[Journal Article] Distinct epigenetic signatures between adult-onset and late-onset depression2021
- Author(s)
  Yamagata H, Ogihara H, Matsuo K, Uchida S, Kobayashi A, Seki T, Kobayashi M, Harada K, Chen C, Miyata S, Fukuda M, Mikuni M, Hamamoto Y, Watanabe Y, Nakagawa S
- Journal Title
  
  Scientific Reports
  
  Volume: 27 Pages: 2296-2296
- DOI
  10.1038/s41598-021-81758-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04905, KAKENHI-PUBLICLY-19H05214, KAKENHI-PROJECT-18H02750, KAKENHI-PROJECT-19K17090
[Journal Article] A Multiscale View of the Mechanisms Underlying Ketamine’s Antidepressant Effects: An Update on Neuronal Calcium Signaling2021
- Author(s)
  Kawatake-Kuno Ayako、Murai Toshiya、Uchida Shusaku
- Journal Title
  
  Frontiers in Behavioral Neuroscience
  
  Volume: 15
- DOI
  10.3389/fnbeh.2021.749180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00198, KAKENHI-PROJECT-21K19707
[Journal Article] Altered expression of long noncoding RNAs in patients with major depressive disorder2019
- Author(s)
  Seki T, Yamagata H, Uchida S, Chen C, Kobayashi A, Kobayashi M, Harada K, Matsuo K, Watanabe Y, Nakagawa S.
- Journal Title
  
  Journal of Psychiatric Research
  
  Volume: 117 Pages: 92-99
- DOI
  10.1016/j.jpsychires.2019.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17090, KAKENHI-PUBLICLY-19H04905, KAKENHI-PUBLICLY-19H05214, KAKENHI-PROJECT-18H02750
[Journal Article] Synaptically Localized Transcriptional Regulators in Memory Formation2018
- Author(s)
  Uchida Shusaku、Shumyatsky Gleb P.
- Journal Title
  
  Neuroscience
  
  Volume: 370 Pages: 4-13
- DOI
  10.1016/j.neuroscience.2017.07.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09807
[Journal Article] Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement2018
- Author(s)
  Uchida Shusaku、Shumyatsky Gleb P.
- Journal Title
  
  Brain Res Bull
  
  Volume: in press
- DOI
  10.1016/j.brainresbull.2018.02.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09807
[Journal Article] Epigenetic mechanisms of major depression: Targeting neuronal plasticity2018
- Author(s)
  Uchida Shusaku、Yamagata Hirotaka、Seki Tomoe、Watanabe Yoshifumi
- Journal Title
  
  Psychiatry Clin Neurosci
  
  Volume: 72 Pages: 212-227
- DOI
  10.1111/pcn.12621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10189, KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-15K09807
[Journal Article] Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression2018
- Author(s)
  Yamagata Hirotaka、Uchida Shusaku、Matsuo Koji、Harada Kenichiro、Kobayashi Ayumi、Nakashima Mami、Higuchi Fumihiro、Watanuki Toshio、Matsubara Toshio、Watanabe Yoshifumi
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 233 Pages: 79-85
- DOI
  10.1016/j.jad.2017.08.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09832, KAKENHI-PROJECT-16K10189, KAKENHI-PROJECT-17K16380
[Journal Article] うつ病におけるヒストン脱アセチル化酵素の役割と新たな治療薬創出の試み2017
- Author(s)
  内田周作、渡邉義文
- Journal Title
  
  精神医学
  
  Volume: 59 Pages: 1045-1054
- NAID
  40021376653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04895
[Journal Article] Identification of commonly altered genes between in major depressive disorder and a mouse model of depression.2017
- Author(s)
  Yamagata Hirotaka、Uchida Shusaku、Matsuo Koji、Harada Kenichiro、Kobayashi Ayumi、Nakashima Mami、Nakano Masayuki、Otsuki Koji、Abe-Higuchi Naoko、Higuchi Fumihiro、Watanuki Toshio、Matsubara Toshio、Miyata Shigeo、Fukuda Masato、Mikuni Masahiko、Watanabe Yoshifumi
- Journal Title
  
  Sci Rep
  
  Volume: 7 Pages: 1-10
- DOI
  10.1038/s41598-017-03291-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10189, KAKENHI-PROJECT-15H04890, KAKENHI-PROJECT-15K09832
[Journal Article] CRTC1 Nuclear Translocation Following Learning Modulates Memory Strength via Exchange of Chromatin Remodeling Complexes on the Fgf1 Gene2017
- Author(s)
  Uchida S, Teubner BJ, Hevi C, Hara K, Kobayashi A, Dave RM, Shintaku T, Jaikhan P, Yamagata H, Suzuki T, Watanabe Y, Zakharenko SS, Shumyatsky GP.
- Journal Title
  
  Cell Rep.
  
  Volume: 18 Pages: 352-366
- DOI
  10.1016/j.celrep.2016.12.052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-16KT0060, KAKENHI-PROJECT-16K10189
[Journal Article] 注目の遺伝子　Sirtuin遺伝子2017
- Author(s)
  内田周作
- Journal Title
  
  分子精神医学
  
  Volume: 17 Pages: 63-65
- Data Source
  KAKENHI-PROJECT-15K09807
[Journal Article] 白血球の遺伝子発現からみた気分障害の診断2017
- Author(s)
  山形弘隆, 内田周作, 關友恵, 渡邉義文
- Journal Title
  
  精神医学
  
  Volume: 59 Pages: 843-848
- Data Source
  KAKENHI-PROJECT-16K10189
[Journal Article] うつ病におけるヒストン脱アセチル化酵素の役割と新たな治療薬創出の試み2017
- Author(s)
  内田周作、渡邉義文
- Journal Title
  
  精神医学
  
  Volume: 59 Pages: 1045-1054
- NAID
  40021376653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09807
[Journal Article] CRTC1 Nuclear Translocation Following Learning Modulates Memory Strength via Exchange of Chromatin Remodeling Complexes on the Fgf1 Gene2017
- Author(s)
  Uchida S, Teubner BJ, Hevi C, Hara K, Kobayashi A, Dave RM, Shintaku T, Jaikhan P, Yamagata H, Suzuki T, Watanabe Y, Zakharenko SS, Shumyatsky GP.
- Journal Title
  
  Cell Rep
  
  Volume: 18 Pages: 352-366
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09807
[Journal Article] ストレスに強い脳をつくる運動トレーニングの制御機構2017
- Author(s)
  内田周作
- Journal Title
  
  体育の科学
  
  Volume: 67 Pages: 315-319
- Data Source
  KAKENHI-PROJECT-15K09807
[Journal Article] Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior.2016
- Author(s)
  Naoko Abe-Higuchi, Shusaku Uchida, Hirotaka Yamagata, Fumihiro Higuchi, Teruyuki Hobara, Kumiko Hara, Ayumi Kobayashi, and Yoshifumi Watanabe
- Journal Title
  
  Biol Psychiatry.
  
  Volume: In press Pages: 815-826
- DOI
  10.1016/j.biopsych.2016.01.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25893152, KAKENHI-PROJECT-26670542, KAKENHI-PROJECT-26860481, KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-15K09807
[Journal Article] Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice.2016
- Author(s)
  Higuchi F, Uchida S, Yamagata H, Abe-Higuchi N, Hobara T, Hara K, Kobayashi A, Shintaku T, Itoh Y, Suzuki T, Watanabe Y.
- Journal Title
  
  J Neurosci.
  
  Volume: 36 Pages: 7253-7267
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09807
[Journal Article] Hippocampal microRNA-124 enhances chronic stress resilience in mice2016
- Author(s)
  Higuchi F, Uchida S, Yamagata H, Abe-Higuchi N, Hobara T, Hara K, Kobayashi A, Shintaku T, Itoh Y, Suzuki T, Watanabe Y.
- Journal Title
  
  J Neurosci.
  
  Volume: 36 Pages: 7253-7267
- DOI
  10.1523/jneurosci.0319-16.2016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-16K10189
[Journal Article] Genetic Demonstration of a Role for Stathmin in Adult Hippocampal Neurogenesis, Spinogenesis, and NMDA Receptor-Dependent Memory.2016
- Author(s)
  Martel G, Uchida S, Hevi C, Chevere-Torres I, Fuentes I, Park YJ, Hafeez H, Yamagata H, Watanabe Y, Shumyatsky GP
- Journal Title
  
  J Neurosci.
  
  Volume: 36 Pages: 1185-1202
- DOI
  10.1523/jneurosci.4541-14.2016
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09807, KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-26670542
[Journal Article] State-dependent changes in the expression of DNA methyltransferases in mood disorder patients2011
- Author(s)
  Higuchi F, Uchida S, Yamagata H, Otsuki K, Hobara T, Abe N, Shibata T, Watanabe Y
- Journal Title
  
  J Psychiatr Res
  
  Volume: 45(10) Pages: 1295-1300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events2011
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  Neuron
  
  Volume: 69 Pages: 359-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 12011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Fujimoto M, Otsuki K, Yamagata H, Hobara T, Abe N, Higuchi F, Shibata T, Hasegawa S, Kida S, Nakai A, Watanabe Y
- Journal Title
  
  Proceedings of the National Academy of Science of the United States of America
  
  Volume: 108(4) Pages: 1681-1686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Epigenetic status of Gdnfin the ventral striatum determines susceptibility and adaptation to daily stressful events2011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Otsuki K, Yamagata H, Hobara T, Suzuki T, Miyata N, Watanabe Y
- Journal Title
  
  Neuron
  
  Volume: 69(2) Pages: 359-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Altered sirtuin deacetylase gene expression in patients with a mood disorder2011
- Author(s)
  Abe N, Uchida S, Otsuki K, Hobara T, Yamagata H, Higuchi F, Shibata T, Watanabe Y
- Journal Title
  
  J Psychiatr Res
  
  Volume: 45(8) Pages: 1106-1112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 12011
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  Proceedings of the National Academy of Science of the United States of
  
  Volume: 108 Pages: 1681-1686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Aberrant REST-mediated transcriptional regulation in major depressive disorder2010
- Author(s)
  Otsuki K, Uchida S, Wakabayashi Y, Matsubara T, Hobara T, Funato H, Watanabe Y
- Journal Title
  
  Journal of Psychiatric Research
  
  Volume: 44(6) Pages: 378-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Aberrant REST-mediated transcriptional regulation in major depressive disorder2010
- Author(s)
  Otsuki K, Uchida S, Wakabayashi Y, Matsubara T, Hobara T, Funato H, Watanabe Y.
- Journal Title
  
  Journal of Psychiatric Research 44
  
  Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Maternal and genetic factors in stress-resilient and -vulnerable rats : A cross-fostering study.2010
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  Brain Research 1316
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591369
[Journal Article] Maternal and genetic factors in stress-resilient and -vulnerable rats : A cross-fostering study2010
- Author(s)
  Shusaku Uchida
- Journal Title
  
  Brain Research 1316
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Maternal and genetic factors in stress-resilient and -vulnerable rats: A cross-fostering study.2010
- Author(s)
  Uchida S, Hara K, Kobayashi A, Otsuki K, Hobara T, Yamagata H, Watanabe Y.
- Journal Title
  
  Brain Research 1316
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Maternal and genetic factors in stress-resilient and-vulnerable rats : A cross-fostering study.2010
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  Brain Research 1316
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents2010
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 30 Pages: 15007-15018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Altered gene expression of histone deacetylases in mood disorder patients2010
- Author(s)
  Hobara T, Uchida S, Otsuki K, Matsubara T, Funato H, Matsuo K, Suetsugi M, Watanabe Y
- Journal Title
  
  Journal of Psychiatric Research
  
  Volume: 44(5) Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Maternal and genetic factors in stress-resilient and -vulnerable rats : A cross-fostering study.2010
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  Brain Research
  
  Volume: 1316 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791126
[Journal Article] Altered gene expression of histone deacetylases in mood disorder patients.2010
- Author(s)
  Hobara T, Uchida S, Otsuki K, Matsubara T, Funato H, Matsuo K, Suetsugi M, Watanabe Y.
- Journal Title
  
  Journal of Psychiatric Research 44
  
  Pages: 378-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents.2010
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 30 Pages: 15007-15018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791126
[Journal Article] Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents2010
- Author(s)
  Uchida S, Hara K, Kobayashi A, Funato H, Hobara T, Otsuki K, Yamagata H, McEwen BS, Watanabe Y
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 30(45) Pages: 15007-15018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Reduced expression of glyoxalase-1 mRNA in mood disorder patients.2008
- Author(s)
  Fujimoto M, Uchida S, Watanuki T, Wakabayashi Y, Otsuki K, Matsubara T, Suetsugi M, Funato H, Watanabe Y.
- Journal Title
  
  Neuroscience Letters 438
  
  Pages: 196-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Characterization of the vulnerability to repeated stress in Fischer 344 rats : possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor2008
- Author(s)
  Shusaku Uchida, 他
- Journal Title
  
  European Journal of Neuroscience 27
  
  Pages: 2250-2261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591369
[Journal Article] State-dependent changes in the expression levels of NCAM-140 and L1 in the peripheral blood cells of bipolar disorders, but not in the major depressive disorders.2008
- Author(s)
  Wakabayashi Y, Uchida S, Funato H, Matsubara T, Watanuki T, Otsuki K, Fujimoto M, Nishida A., Watanabe Y.
- Journal Title
  
  Prog. Neuropsychopharmacol. Biol. Psychiatry 32
  
  Pages: 1199-1205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] グルココルチコイド受容体2008
- Author(s)
  内田周作他
- Journal Title
  
  分子精神医学 8
  
  Pages: 61-64
- Data Source
  KAKENHI-PROJECT-18790832
[Journal Article] Increased expression of splicing factor SRp20 mRNA in bipolar disorder patients.2008
- Author(s)
  Watanuki T, Funato H, Uchida S, Matsubara T, Kobayashi A, Wakabayashi Y, Otsuki K, Nishida A, Watanabe Y
- Journal Title
  
  Journal of Affective Disorders 110
  
  Pages: 62-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Increased expression of splicing factor SRp20 mRNA in bipolar disorder patients2008
- Author(s)
  Watanuki T, Funato H, Uchida S, Matsubara T, Kobayashi A, Wakabayashi Y, Otsuki K, Nishida A, Watanabe Y
- Journal Title
  
  Journal of Affective Disorders 110
  
  Pages: 62-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790817
[Journal Article] Altered expression of neurotrophic factors in patients with major depression.2008
- Author(s)
  Otsuki K, Uchida S, Watanuki T, Wakabayashi Y, Fujimoto M, Matsubara T, Funato H, Watanabe Y.
- Journal Title
  
  Journal of Psychiatric Research 42
  
  Pages: 1145-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Characterization of the vulnerability to repeated restraint stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor.2008
- Author(s)
  Uchida S, Nishida A, Hara K, Kamemoto T, Suetsugi M, Fujimoto M, Watanuki T, Wakabayashi Y, Otsuki K, McEwen BS, Watanabe Y.
- Journal Title
  
  European Journal of Neuroscience 27
  
  Pages: 2250-2261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790844
[Journal Article] Chronic reduction in dietary tryptophan leads to a selective impairment of contextual fear memory in mice2007
- Author(s)
  Shusaku Uchida
- Journal Title
  
  Brain Research 1149
  
  Pages: 149-156
- Data Source
  KAKENHI-PROJECT-18790832
[Journal Article] Chronic reduction in dietary tryptophan leads to a selective impairment of contextual fear memory in mice2007
- Author(s)
  Shusaku Uchida 他
- Journal Title
  
  Brain Research 1149
  
  Pages: 149-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790832
[Journal Article] Tight regulation of transgene expression by tetracycline-dependent activator and repressor in brain2006
- Author(s)
  Shusaku Uchida
- Journal Title
  
  Genes, Brain, and Behavior 5
  
  Pages: 96-106
- Data Source
  KAKENHI-PROJECT-18790832
[Journal Article] Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1.
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  PNAS
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791126
[Journal Article] Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events.
- Author(s)
  Shusaku Uchida, et al.
- Journal Title
  
  Neuron
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791126
[Patent] ５０歳未満発症うつ病の罹患の有無を予測する方法2017
- Inventor(s)
  山形弘隆、内田周作、渡邊義文、浜本義彦、荻原宏是
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-091149
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] エピジェネティクスの視点から紐解く脳内ストレス適応の分子メカニズム2021
- Author(s)
  内田周作
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] エピジェネティクスの視点から紐解く脳内ストレス適応の分子メカニズム2021
- Author(s)
  内田周作
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04905
[Presentation] Epigenetic mechanisms driving synaptic plasticity and affective states under stressful situation2021
- Author(s)
  Shusaku Uchida
- Organizer
  日本神経科学会
- Data Source
  KAKENHI-PUBLICLY-21H00198
[Presentation] ケタミン代謝産物による持続的な抗うつ作用の分子神経メカニズム2021
- Author(s)
  Ayako Kawatake-Kuno, Erina Ishimori, Haiyan Li, Yusuke Sakai, Yuki Funayama, Hiromichi Inaba, Naoya Oishi, Toshiya Murai, Shusaku Uchida
- Organizer
  日本神経化学会
- Data Source
  KAKENHI-PUBLICLY-21H00198
[Presentation] ケタミン代謝産物による持続的な抗うつ作用の分子神経メカニズム2021
- Author(s)
  Ayako Kawatake-Kuno, Erina Ishimori, Haiyan Li, Yusuke Sakai, Yuki Funayama, Hiromichi Inaba, Naoya Oishi, Toshiya Murai, Shusaku Uchida
- Organizer
  日本神経化学会
- Data Source
  KAKENHI-PROJECT-21K19707
[Presentation] エピジェネティクスの視点から紐解く脳内ストレス適応の分子メカニズム2021
- Author(s)
  内田周作
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05214
[Presentation] ストレス感受性制御における脳内分子基盤2021
- Author(s)
  内田周作
- Organizer
  日本精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-21K19707
[Presentation] ストレス感受性制御における脳内分子基盤2021
- Author(s)
  内田周作
- Organizer
  日本精神神経薬理学会
- Data Source
  KAKENHI-PUBLICLY-21H00198
[Presentation] Epigenetic mechanisms driving synaptic plasticity and affective states under stressful situation2021
- Author(s)
  Shusaku Uchida
- Organizer
  日本神経科学会
- Data Source
  KAKENHI-PROJECT-21K19707
[Presentation] 遺伝・環境相互作用によるレジリエンス形成の分子基盤2020
- Author(s)
  内田周作
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第４回日本精神薬学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] Molecular and neural mechanisms of stress susceptibility and resilience2020
- Author(s)
  内田周作
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第４回日本精神薬学会総会・学術集会
- Data Source
  KAKENHI-PUBLICLY-19H04905
[Presentation] 遺伝・環境相互作用によるレジリエンス形成の分子基盤2020
- Author(s)
  内田周作
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第４回日本精神薬学会総会・学術集会
- Data Source
  KAKENHI-PUBLICLY-19H05214
[Presentation] Epigenetic mechanisms of stress-induced depression2019
- Author(s)
  内田周作
- Organizer
  6th Congress of AsCNP
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05214
[Presentation] Molecular and neural mechanisms of stress susceptibility and resilience2019
- Author(s)
  内田周作
- Organizer
  Neuro2019
- Invited
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] Epigenetic mechanisms of stress susceptibility and resilience2019
- Author(s)
  内田周作
- Organizer
  American College of Neuropsychopharmacology
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] ストレスに強い脳と弱い脳の分子メカニズム2019
- Author(s)
  内田周作
- Organizer
  日本精神神経学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04905
[Presentation] Epigenetic mechanisms of stress-induced depression2019
- Author(s)
  内田周作
- Organizer
  6th Congress of AsCNP
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] Molecular and neural mechanisms of stress susceptibility and resilience2019
- Author(s)
  内田周作
- Organizer
  Neuro2019
- Data Source
  KAKENHI-PUBLICLY-19H04905
[Presentation] ストレス関連精神疾患におけるエピジェネティクス制御機構の破綻と神経可塑性異常2019
- Author(s)
  内田周作
- Organizer
  6th Congress of AsCNP
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04905
[Presentation] Molecular and neural mechanisms of stress susceptibility and resilience2019
- Author(s)
  内田周作
- Organizer
  Neuro2019
- Data Source
  KAKENHI-PUBLICLY-19H05214
[Presentation] ストレスに強い脳と弱い脳の分子メカニズム2019
- Author(s)
  内田周作
- Organizer
  日本精神神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] ストレスに強い脳と弱い脳の分子メカニズム2019
- Author(s)
  内田周作
- Organizer
  日本精神神経学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05214
[Presentation] Epigenetic mechanisms of stress susceptibility and resilience2019
- Author(s)
  内田周作
- Organizer
  American College of Neuropsychopharmacology
- Data Source
  KAKENHI-PUBLICLY-19H05214
[Presentation] Epigenetic mechanisms of stress susceptibility and resilience2019
- Author(s)
  内田周作
- Organizer
  American College of Neuropsychopharmacology
- Data Source
  KAKENHI-PUBLICLY-19H04905
[Presentation] 運動によるストレスレジリエンス獲得の分子メカニズム2018
- Author(s)
  内田周作
- Organizer
  第73回日本体力医学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] ストレス関連精神疾患におけるエピジェネティクス制御機構の破綻と神経可塑性異常2018
- Author(s)
  内田周作
- Organizer
  第59回日本組織細胞化学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] The usefulness of long noncoding RNAs as biomarkers of major depressive disorder2018
- Author(s)
  Tomoe Seki, Hirotaka Yamagata, Shusaku Uchida, Chong Chen, Kenichiro Harada, Koji Matsuo, Yoshifumi Watanabe, Shin Nakagawa
- Organizer
  Society for Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] ストレス関連精神疾患におけるカルシウムシグナリングの役割2018
- Author(s)
  内田周作
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02750
[Presentation] うつ病患者白血球とうつ病モデルマウス血液に共通した遺伝子発現変化2017
- Author(s)
  山形弘隆, 内田周作, 松尾幸治, 原田健一郎, 宮田茂雄, 福田正人, 三國雅彦, 渡邉義文
- Organizer
  第39回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] Altered expression of long noncoding RNAs in patients with major depression2017
- Author(s)
  關友恵、内田周作
- Organizer
  北米神経科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] Altered expression of long noncoding RNAs in patients with major depression2017
- Author(s)
  關友恵、内田周作
- Organizer
  北米神経科学会
- Data Source
  KAKENHI-PROJECT-15K09807
[Presentation] MicroRNA profiling of the ventral hippocampus in stress-resilient and stress-susceptible mice2017
- Author(s)
  内田周作
- Organizer
  北米神経科学会
- Data Source
  KAKENHI-PROJECT-15K09807
[Presentation] MicroRNA profiling of the ventral hippocampus in stress-resilient and stress-susceptible mice2017
- Author(s)
  S. UCHIDA, H. YAMAGATA, T. SEKI, K. HARA, A. KOBAYASHI, Y. WATANABE
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] ストレス適応機構におけるヒストン脱アセチル化酵素の役割の解析2017
- Author(s)
  樋口文宏, 内田周作, 山形弘隆, 關友恵, 渡辺義文
- Organizer
  第39回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] うつ病・不安障害におけるサーチュインの役割と創薬への可能性2017
- Author(s)
  内田周作
- Organizer
  第39回日本生物学的精神医学会第47回日本神経精神薬理合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09807
[Presentation] 非コードRNAによる脳機能制御とその破綻による精神疾患2017
- Author(s)
  内田周作
- Organizer
  第113回日本精神神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] Altered plasma protein glycosylation in depression2017
- Author(s)
  H. YAMAGATA, S. UCHIDA K. MATSUO, K. HARADA, Y. WATANABE
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] うつ病・不安障害におけるサーチュインの役割と創薬への可能性2017
- Author(s)
  内田周作
- Organizer
  第39回日本生物学的精神医学会第47回日本神経精神薬理合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] 非コードRNAによる脳機能制御とその破綻による精神疾患2017
- Author(s)
  内田周作
- Organizer
  第113回日本精神神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09807
[Presentation] Altered expression of long, noncoding RNAs in patients with major depression2017
- Author(s)
  T. SEKI, H. YAMAGATA, S. UCHIDA, K. HARADA, K. MATSUO, Y. WATANABE
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] 精神疾患領域における標的分子の探索と創薬への可能性うつ病・不安障害におけるサーチュインの役割と創薬への可能性2017
- Author(s)
  内田周作, 樋口尚子, 山形弘隆, 渡辺義文
- Organizer
  第39回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] MicroRNA profiling of the ventral hippocampus in stress-resilient and stress-susceptible mice2017
- Author(s)
  内田周作
- Organizer
  北米神経科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] 大うつ病性障害患者における長鎖非コードRNAの発現解析2017
- Author(s)
  關友恵, 山形弘隆, 内田周作, 原田健一郎, 松尾幸治, 渡邉義文
- Organizer
  第39回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] うつ病の発症脆弱性の分子機構を考える.2016
- Author(s)
  3.渡辺義文, 内田周作, 山形弘隆, 樋口文宏
- Organizer
  第38回日本生物学的精神医学会第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] BubR1 を介した神経突起伸展の制御2016
- Author(s)
  山形弘隆、内田周作、樋口文宏、芳原輝之、渡邉義文
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡コンベンションセンター（福岡県・福岡市）
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] Identification of biomarkers in blood in elder patients with early-onset major depressive disorder.2016
- Author(s)
  6.Hirotaka Yamagata, Shuaku Uchida, Kenichiro Harada, Fumihiro Higuchi, Koji Matsuo, Shigeo Miyata, Masato Fukuda, Masahiko Mikuni, Yoshifumi Watanabe
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego Convention Center (USA)
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] Hippocampal microRNA-124 enhances chronic stress resilience in mice2016
- Author(s)
  樋口文宏、内田周作、山形弘隆、渡辺義文
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡コンベンションセンター（福岡県・福岡市）
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] うつ病の発病脆弱性の分子機構を考える2016
- Author(s)
  渡辺義文、内田周作、山形弘隆、樋口文宏
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡コンベンションセンター（福岡県・福岡市）
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] Hippocampal SIRT1 signaling mediates stress resilience and susceptibility in mice2016
- Author(s)
  内田周作、樋口尚子、山形弘隆、樋口文宏、芳原輝之、原久美子、古林亜由美、渡辺義文
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡コンベンションセンター（福岡県・福岡市）
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] ストレス適応破綻からみたうつ病態における神経可塑性異常とその分子基盤2016
- Author(s)
  内田周作、山形弘隆、芳原輝之、樋口文宏、樋口尚子、渡辺義文
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡コンベンションセンター
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] うつ病と神経細胞死2016
- Author(s)
  4.山形弘隆, 内田周作, 樋口文宏, 渡邉義文
- Organizer
  第38回日本生物学的精神医学会第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] Hippocampal SIRT1 signaling mediates depression-related behacior in mice.2016
- Author(s)
  1.Shusaku Uchida, Naoko Abe-Higuchi, Fumihiro Higuchi, Hirotaka Yamagata, Koji Matsuo, Yoshifumi Watanabe
- Organizer
  Society of Biological Psychiatry 71st Annual meeting
- Place of Presentation
  Atlanta Convention Center (USA)
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] うつ病と神経細胞死2016
- Author(s)
  山形弘隆、内田周作、樋口文宏、渡邉義文
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡コンベンションセンター（福岡県・福岡市）
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] Identification of biomarkers in blood in geriatric patients with early-onset major depressive disorder2016
- Author(s)
  YAMAGATA H, UCHIDA S, HARADA K, HIGUCHI F, MATSUO K, MIYATA S, FUKUDA M, MIKUNI M, WATANABE Y
- Organizer
  Neuroscience 2016, SfN's 46th annual meeting
- Place of Presentation
  San Diego Convention Center, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10189
[Presentation] ストレス適応破綻からみたうつ病態における神経可塑性異常とその分子基盤2016
- Author(s)
  内田周作、山形弘隆、芳原輝之、樋口文宏、樋口尚子、渡辺義文
- Organizer
  第38回日本生物学的精神医学会第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] Genetic activation of stathmin impairs adult hippocampal neurogenesis, spinogenesis, and NMDA receptor-dependent memory2015
- Author(s)
  Shusaku Uchida, Itzamarie Chevere-Torres, Charles Hevi, Gleb P. Shumyatsky
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  McCormick Place, Chicago, USA
- Year and Date
  2015-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09807
[Presentation] Genetic activation of stathmin impairs adult hippocampal neurogenesis, spinogenesis, and NMDA receptor-dependent memory2015
- Author(s)
  Shusaku Uchida, Itzamarie Chevere-Torres, Charles Hevi, Gleb P. Shumyatsky
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] レジリエンスの視点からうつ病の発症・回復の分子メカニズムを理解する2015
- Author(s)
  内田周作
- Organizer
  生物学的精神医学会・神経精神薬理学会合同年会
- Place of Presentation
  タワーホール船堀・東京都江戸川区
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-15K09807
[Presentation] エピジェネティクスによるうつ病の分子・細胞基盤2015
- Author(s)
  内田周作
- Organizer
  生物学的精神医学会・神経精神薬理学会合同年会
- Place of Presentation
  タワーホール船堀・東京都江戸川区
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15K09807
[Presentation] 気分障害患者におけるghrelin濃度と脳体積との関連2011
- Author(s)
  松尾幸治、中野雅之、中島麻美、古林亜由美、原久美子、藤井優子、橋本亜希子、江頭一輝、内田周作、松原敏郎、渡邉義文
- Organizer
  第33回日本生物学的精神医学会
- Place of Presentation
  グランパシフィックLe Daiba東京
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] Association of Plasma Ghrelin Level and Morphometric Abnormalities in Patients with Mood Disorders2011
- Author(s)
  Matsuo K, Nakano M, Nakashima M, Kobayashi A, Hara K, Fujii Y, Hashimoto A, Egashira K, Uchida S, Matsubara T, Watanabe Y
- Organizer
  17th Annual meeting of the organization on Human Brain Mapping
- Place of Presentation
  ケベック、カナダ
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] 気分障害患者におけるグレリン濃度と脳形態異常との関連2011
- Author(s)
  松尾幸治, 中野雅之, 中島麻美, 古林亜由美, 原久美子, 藤井優子, 橋本亜希子, 江頭一輝, 内田周作, 松原敏郎, 渡邉義文
- Organizer
  第33回日本生物学的精神医学会
- Place of Presentation
  東京ホテルグランパシフィックLE DAIBA
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents.2010
- Author(s)
  Shusaku Uchida, et al.
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンディエゴ・コンベンションセンター
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22791126
[Presentation] Involvement of REST4-mediated gene regulations in stress vulnera bility2010
- Author(s)
  内田周作, 他
- Organizer
  第33回日本神経科学会
- Place of Presentation
  兵庫・神戸・国際会議場
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22791126
[Presentation] Antidepressants increase GDNF gene transcription through the histone modifications by HDAC42010
- Author(s)
  Otsuki K, Uchida S, Yamagata H, Watanabe Y
- Organizer
  Neuroscience 2010, SfN' s 40th annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] Epigenetic regulation of GDNF gene in a mouse model of depression and antidepressant action.2009
- Author(s)
  Shusaku Uchida
- Organizer
  第31回日本生物学的精神医学会年会
- Place of Presentation
  京都
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-20591369
[Presentation] HDAC2-mediated epigenetic repression of the GDNF gene in the striatum modulates behavioral vulnerability to stress.2009
- Author(s)
  Shusaku Uchida, et al.
- Organizer
  第32回日本神経科学会年会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20790844
[Presentation] HDAC2-mediated epigenetic repression of the GDNF gene in the ventral striatum modulates behavioral vulnerability to stress2009
- Author(s)
  Shusaku Uchida
- Organizer
  Society for Neuroscience
- Place of Presentation
  米国シカゴ
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20591369
[Presentation] Antidepressants increase transcriptional activity of GDNF gene via the histone modification2009
- Author(s)
  Otsuki K, Uchida S, Watanabe Y
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] HDAC2-mediated epigenetic repression of the GDNF gene in the striatum modulates behavioral vulnerability to stress2009
- Author(s)
  Shusaku Uchida
- Organizer
  第32回日本神経科学会年会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20591369
[Presentation] HDAC2-mediated epigenetic repression of the GDNF gene in the ventral striatum modulates behavioral vulnerability to stress2009
- Author(s)
  Shusaku Uchida
- Organizer
  Society for Neuroscience
- Place of Presentation
  米国シカゴ
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20790844
[Presentation] HDAC2-mediated epigenetic repression of the GDNF gen e in the striatum modulates behavioral vulnerability to stress2009
- Author(s)
  Shusaku Uchida
- Organizer
  Neuroscience 2009
- Place of Presentation
  McCormick Place Convention Center, Chicago, U.S.A.
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] Epigenetic regulation of GDNF gene in a mouse model of depression and antidepressant action.2009
- Author(s)
  Shusaku Uchida, et al.
- Organizer
  第31回日本生物学的精神医学会年会
- Place of Presentation
  京都
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-20790844
[Presentation] HDAC2-mediated epigenetic repression of the GDNF gene in the striatum modulates behavioral vulnerability to stress2009
- Author(s)
  Shusaku Uchida
- Organizer
  第32回日本神経科学会年会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20790844
[Presentation] HDAC2-mediated epigenetic repression of the GDNF gene in the ventral striatum modulates behavioral vulnerability to stress.2009
- Author(s)
  Shusaku Uchida, et al.
- Organizer
  Society for Neuroscience
- Place of Presentation
  シカゴ
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20790844
[Presentation] Characterization of vulnerability to repeated restraint stress in Fischer344 rats2007
- Author(s)
  Shusaku Uchida 他
- Organizer
  北米神経科学会
- Place of Presentation
  サンディェゴ
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-18790832
[Presentation] ストレス脆弱性モアルフツトにおけるマイクロRNAを介したグルココルチコイド受容体の発現調節異常2007
- Author(s)
  内田周作他
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2007-01-11
- Data Source
  KAKENHI-PROJECT-18790832

1. WATANABE Yoshifumi (90182964)

# of Collaborated Projects: 6 results

# of Collaborated Products: 20 results
2. YAMGATA Hirotaka (10549934)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
3. SUETSUGI Masatomo (40294631)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MATSUO Koji (00292912)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. EGASHIRA Kazuteru (90437624)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. MATSUBARA Toshio (60526896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. OTSUKI Koji (10535256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. NISHIDA Akira (20372708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. WATANUKI Toshio (80610865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 橋本学 (80314805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 土屋健 (00346561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 有田一信 (80379974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 樋口文宏 (60711249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
14. 樋口尚子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 芳原輝之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 關友恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 福田正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 鈴木孝禎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 李海燕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uchida Shusaku 内田 周作

UCHIDA Shusaku 内田 周作

Research Projects

Research Products

Co-Researchers

心の健康増進をめざしたストレス感受性の生物学的基盤の解明Principal Investigator

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細胞内分子複合体の多様性から紐解くストレス感受性の個体差構築のメカニズムPrincipal Investigator

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運動によるストレスレジリエンス獲得の分子・神経メカニズム解明Principal Investigator

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ストレス感受性の個性創発の分子神経基盤解析Principal Investigator

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ストレス感受性制御を司る脳内メカニズムの構成的理解Principal Investigator

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Molecula and neral mechanisms of individual- and -sex differences in behavioral resposne to stressPrincipal Investigator

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Elucidating molecular mechanisms underlying stress vulnerabilityPrincipal Investigator

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Principal Investigator

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うつモデルマウスにおけるエピジェネティックな遺伝子発現調節異常の検討Principal Investigator

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Role of splicing factors in the pathogenesis of mood disordersPrincipal Investigator

Principal Investigator

Uchida Shusaku 内田周作

UCHIDA Shusaku 内田周作