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MATSUMOTO KENJIRO  松本 健次郎

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Matsumoto Kenjiro  松本 健次郎

MATSUMOTO Kenjiro  松本 健次郎

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Researcher Number 10406770
Other IDs
Affiliation (Current) 2025: 同志社女子大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2023: 同志社女子大学, 薬学部, 教授
2018 – 2022: 京都薬科大学, 薬学部, 准教授
2013 – 2017: 京都薬科大学, 薬学部, 助教
2006 – 2009: 城西国際大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy / Applied pharmacology / Biological pharmacy / Medical pharmacy
Keywords
Principal Investigator
温度感受性受容体 / 知覚神経 / 内臓痛覚過敏 / 過敏性腸症候群 / TRPチャネル / 内臓痛 / 炎症性腸疾患 / Mitragynine / オピオイド / 経口活性 … More / モルヒネ / インドールアルカロイド / 抗侵害作用 / μオピオイド受容体 / TRPV2 / 大腸炎 / マクロファージ / 消化管 / TRPチャンネル / 脳腸相関 / 社会的敗北ストレス / TRPM8 / 生理学 / 薬理学 / 血管透過性 / 血管内皮 / 大腸炎関連がん / 酸味 / 分化 / 透過性 / 血管内皮細胞 / 味覚 / ヒト検体 / 消化管炎症 / TRPM2 / δオピオイド受容体 / オピオイド受容体 / 痛み / ミトラガイニン / 消化管運動 / インドールアルカノイド / 7-Hydroxymitragynine / 精神依存性 / κオピオイド受容体 Less
  • Research Projects

    (6 results)
  • Research Products

    (75 results)
  • Co-Researchers

    (5 People)
  •  過敏性腸症候群の内臓痛覚過敏制御を志向したTRPV2の機能解明Principal Investigator

    • Principal Investigator
      松本 健次郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Doshisha Women's College of Liberal Arts
      Kyoto Pharmaceutical University
  •  Role of TRPM8 in the irritable bowel syndrome like symptoms induced by early-childhood social defeat stress in micePrincipal Investigator

    • Principal Investigator
      Matsumoto Kenjiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kyoto Pharmaceutical University
  •  The role of TRPV4 in the regulation of gastrointestinal disordersPrincipal Investigator

    • Principal Investigator
      Matsumoto Kenjiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pharmacology in pharmacy
    • Research Institution
      Kyoto Pharmaceutical University
  •  Role of transient receptor potential melastatin 2 channels in visceral nociception and hypersensitivity in ratsPrincipal Investigator

    • Principal Investigator
      Matsumoto Kenjiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kyoto Pharmaceutical University
  •  Antinociceptive and side effects of novel oral active indole alkaloidsPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Kenjiro
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Josai International University
  •  モルヒネより強力かつ経口有効な新規鎮痛インドールアルカロイドの薬理作用解析Principal Investigator

    • Principal Investigator
      松本 健次郎
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Josai International University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Patent

  • [Journal Article] Transient receptor potential melastatin 2 is involved in trinitrobenzene sulfonic acid-induced acute and chronic colitis-associated fibrosis progression in mice2024

    • Author(s)
      Nakamoto Tomohiro、Matsumoto Kenjiro、Yasuda Hiroyuki、Mori Yasuo、Kato Shinichi
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 154 Issue: 1 Pages: 18-29

    • DOI

      10.1016/j.jphs.2023.11.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06656
  • [Journal Article] Immunohistochemical characterization of transient receptor potential vanilloid types 2 and 1 in a trinitrobenzene sulfonic acid-induced rat colitis model with visceral hypersensitivity2022

    • Author(s)
      Matsumoto Kenjiro、Sugimoto Fumika、Mizuno Toshiki、Hayashi Taisei、Okamura Ririka、Nishioka Takuya、Yasuda Hiroyuki、Horie Syunji、Kido Mizuho A.、Kato Shinichi
    • Journal Title

      Cell and Tissue Research

      Volume: 391 Issue: 2 Pages: 287-303

    • DOI

      10.1007/s00441-022-03723-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06633, KAKENHI-PROJECT-22K06656
  • [Journal Article] Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice2021

    • Author(s)
      Matsumoto Kenjiro、Takata Kana、Yamada Daisuke、Usuda Haruki、Wada Koichiro、Tada Maaya、Mishima Yoshiyuki、Ishihara Shunji、Horie Syunji、Saitoh Akiyoshi、Kato Shinichi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 16276-16276

    • DOI

      10.1038/s41598-021-95916-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07109, KAKENHI-PROJECT-19H04032, KAKENHI-PROJECT-21K07961
  • [Journal Article] Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis2021

    • Author(s)
      Kenjiro Matsumoto, Minako Suenaga, Yumi Mizutani, Kohei Matsui, Ayano Yoshida, Tomohiro Nakamoto, and Shinichi Kato
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Journal Article] Protective effect of TRPM8 against indomethacin-induced small intestinal injury via the release of calcitonin gene-related peptide in mice2021

    • Author(s)
      Aliaa Fouad, Kenjiro Matsumoto, Kikuko Amagase, Hiroyuki Yasuda, Makoto Tominaga, and Shinichi Kato
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: in press

    • NAID

      130008060359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Journal Article] Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis2021

    • Author(s)
      Matsumoto Kenjiro、Suenaga Minako、Mizutani Yumi、Matsui Kohei、Yoshida Ayano、Nakamoto Tomohiro、Kato Shinichi
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 146 Issue: 3 Pages: 125-135

    • DOI

      10.1016/j.jphs.2021.03.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Journal Article] Protective Effect of TRPM8 against Indomethacin-Induced Small Intestinal Injury <i>via</i> the Release of Calcitonin Gene-Related Peptide in Mice2021

    • Author(s)
      Fouad Aliaa、Matsumoto Kenjiro、Amagase Kikuko、Yasuda Hiroyuki、Tominaga Makoto、Kato Shinichi
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 44 Issue: 7 Pages: 947-957

    • DOI

      10.1248/bpb.b21-00045

    • NAID

      130008060359

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2021-07-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Journal Article] Role of transient receptor potential vanilloid subtype 4 in the regulation of azoymethane/dextran sulphate sodium-induced colitis-associated cancer in mice.2020

    • Author(s)
      Matsumoto K, Deguchi A, Motoyoshi A, Morita A, Maebashi U, Nakamoto T, Kawanishi S, Sueyoshi M, Nishimura K, Takata K, Tominaga M, Nakahara T, Kato S.
    • Journal Title

      Eur J Pharmacol

      Volume: 867 Pages: 172853-172853

    • DOI

      10.1016/j.ejphar.2019.172853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Journal Article] Leukotriene B4 receptor type 2 (BLT2) accelerates the healing of intestinal lesions by promoting epithelial cell proliferation2020

    • Author(s)
      Matsumoto Y, Matsuya Y, Kano N, Amagase K, Saeki K, Matsumoto K, Yokomizo T, Kato S
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics

      Volume: 373 Issue: 1 Pages: 1-9

    • DOI

      10.1124/jpet.119.263145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06692, KAKENHI-PROJECT-19K07109, KAKENHI-PROJECT-19KK0199, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-18K06923
  • [Journal Article] Transient receptor potential vanilloid 4 mediates sour taste sensing via type III taste cell differentiation.2019

    • Author(s)
      Matsumoto K, Ohishi A, Iwatsuki K, Yamazaki K, Takayanagi S, Tsuji M, Aihara E, Utsumi D, Tsukahara T, Tominaga M, Nagasawa K, Kato S.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 6686-6686

    • DOI

      10.1038/s41598-019-43254-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Journal Article] G protein-coupled receptor 40 activation ameliorates dextran sulfate sodium-induced colitis in mice via the upregulation of glucagon-likepeptide-2.2019

    • Author(s)
      Kato S, Utsumi D, Matsumoto K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 140 Issue: 2 Pages: 144-152

    • DOI

      10.1016/j.jphs.2019.05.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Journal Article] Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of post-operative ileus2018

    • Author(s)
      Matsumoto Kenjiro、Kawanaka Hiroki、Hori Masatoshi、Kusamori Kosuke、Utsumi Daichi、Tsukahara Takuya、Amagase Kikuko、Horie Syunji、Yamamoto Akira、Ozaki Hiroshi、Mori Yasuo、Kato Shinichi
    • Journal Title

      American Journal of Physiology-Gastrointestinal and Liver Physiology

      Volume: 印刷中 Issue: 1 Pages: G104-G116

    • DOI

      10.1152/ajpgi.00305.2017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07968, KAKENHI-PROJECT-18K06688, KAKENHI-PROJECT-16K08287, KAKENHI-PLANNED-26111004
  • [Journal Article] Transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 contribute to the progression of colonic inflammation in dextran sulfate sodium-induced colitis in mice.2018

    • Author(s)
      Utsumi D, Matsumoto K, Tsukahara T, Amagase K, Tominaga M, Kato S.
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 36 Issue: 3 Pages: 121-132

    • DOI

      10.1016/j.jphs.2017.12.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08287, KAKENHI-PROJECT-15H02501
  • [Journal Article] Transient receptor potential vanilloid 4 channel regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis.2018

    • Author(s)
      Matsumoto K*, Yamaba R, Inoue K, Utsumi D, Tsukahara T, Amagase K, Tominaga M, Kato S.
    • Journal Title

      British Journal of Pharmacology

      Volume: 175 Issue: 1 Pages: 84-99

    • DOI

      10.1111/bph.14072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08287, KAKENHI-PLANNED-15H05928
  • [Journal Article] Serotonin/5-hydroxytryptamine-3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis2016

    • Author(s)
      Utsumi D, Matsumoto K, Amagase K, Horie S, Kato S.
    • Journal Title

      Br. J. Pharmacol.,

      Volume: 173 Issue: 11 Pages: 1835-1849

    • DOI

      10.1111/bph.13482

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07968, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25460110, KAKENHI-PROJECT-25860395
  • [Journal Article] Role of transient receptor potential melastatin 2 (TRPM2) channels in visceral nociception and hypersensitivity2016

    • Author(s)
      Matsumoto K, Takagi K, Kato A, Ishibashi T, Mori Y, Tashima K, Mitsumoto A, Kato S, Horie S.
    • Journal Title

      Exp Neurol

      Volume: 285 Pages: 41-41

    • DOI

      10.1016/j.expneurol.2016.09.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460127, KAKENHI-PROJECT-15K07968, KAKENHI-PROJECT-16K08287
  • [Journal Article] Differences in the morphine-induced inhibition of small and large intestinal transit: Involvement of central and peripheral μ-opioid receptors in mice.2016

    • Author(s)
      Matsumoto K, Umemoto H, Mori T, Akatsu R, Saito S, Tashima K, Shibasaki M, Kato S, Suzuki T, Horie S.
    • Journal Title

      Eur J Pharmacol

      Volume: 771 Pages: 220-228

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Journal Article] Therapeutic action of 5-HT3 receptor antagonists targeting peritoneal macrophages in postoperative ileus.2015

    • Author(s)
      Maehara T; Matsumoto K; Horiguchi K; Kondo M; Iino S; Horie S; Murata T; Tsubone H; Shimada S; Ozaki H; Hori M.
    • Journal Title

      Br J Pharmacol

      Volume: 172(4) Issue: 4 Pages: 1136-1147

    • DOI

      10.1111/bph.13006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-24590250, KAKENHI-PROJECT-25860395, KAKENHI-PROJECT-26660225, KAKENHI-PROJECT-26860926, KAKENHI-PROJECT-15K07968, KAKENHI-PROJECT-15K08150, KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-25460947, KAKENHI-PROJECT-25252049, KAKENHI-PROJECT-24248050
  • [Journal Article] L-cysteine/d,L-homocysteine-regulated ileum motility via system L and B°,+ transporter: Modification by inhibitors of hydrogen sulfide synthesis and dietary treatments.2015

    • Author(s)
      Yamane S, Nomura R, Yanagihara M, Nakamura H, Fujino H, Matsumoto K, Horie S, Murayama T.
    • Journal Title

      Eur J Pharmacol.

      Volume: 764 Pages: 471-479

    • DOI

      10.1016/j.ejphar.2015.07.042

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07968, KAKENHI-PROJECT-26460060, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25460091, KAKENHI-PROJECT-25860395
  • [Journal Article] Transient receptor potential cation channels in visceral pain2015

    • Author(s)
      Matsumoto K, Kato S, Horie S
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 146 Issue: 4 Pages: 233-235

    • DOI

      10.1254/fpj.146.233

    • NAID

      130005129743

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Journal Article] TRPM8 has a key role in experimental colitis-induced visceral hyperalgesia in mice2014

    • Author(s)
      Takuji Hosoya, Kenjiro Matsumoto, Kimihito Tashima, Hiroyuki Nakamura, Hiromichi Fujino, Toshihiko Murayama, Syunji Horie
    • Journal Title

      Neurogastroenterology and Motility

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Journal Article] Immunohistochemical analysis of altered serotonin signaling and transient receptor potential vanilloid 1 channels in experimental colitis mice2014

    • Author(s)
      Matsumoto K
    • Journal Title

      Yakugaku Zasshi

      Volume: 134 Pages: 1165-1170

    • NAID

      130004712972

    • Open Access
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Journal Article] TRPM8 has a key role in experimental colitis-induced visceral hyperalgesia in mice2014

    • Author(s)
      Hosoya T, Matsumoto K, Tashima K, Nakamura H, Fujino H, Murayama T, Horie S
    • Journal Title

      Neurogastroenterol Motil

      Volume: 印刷中 Issue: 8 Pages: 1112-1121

    • DOI

      10.1111/nmo.12368

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-24790536, KAKENHI-PROJECT-25460091, KAKENHI-PROJECT-25860395, KAKENHI-PROJECT-26460060, KAKENHI-PROJECT-26460093
  • [Journal Article] Neuronal Nitric Oxide Synthase-Derived Nitric Oxide Is Involved in Gastric Mucosal Hyperemic Response to Capsaicin in Rats2013

    • Author(s)
      Raimura M, Tashima K, Matsumoto K, Tobe S, Chino A, Namiki T, Terasawa K, Horie
    • Journal Title

      Pharmacology

      Volume: 92 Issue: 1-2 Pages: 60-70

    • DOI

      10.1159/000351853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-24790536, KAKENHI-PROJECT-25860395
  • [Journal Article] Increased Expression of 5-HT3 and NK 1 Receptors in 5-Fluorouracil-Induced Mucositis in Mouse Jejunum.2013

    • Author(s)
      Matsumoto K, Nakajima T, Sakai H, Kato S, Sagara A, Arakawa K, Tashima K, Narita M, Horie S
    • Journal Title

      Dig Dis Sci

      Volume: 58 Issue: 12 Pages: 3440-3450

    • DOI

      10.1007/s10620-013-2709-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790536, KAKENHI-PROJECT-24790582, KAKENHI-PROJECT-25860395
  • [Journal Article] Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon American Journal of Physiology2009

    • Author(s)
      松本健次郎, 他7名
    • Journal Title

      Gastrointestinal and Liver Physiology 54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Journal Article] Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine : high abundance and sensitivity in rectum and distal colon.2009

    • Author(s)
      Matsumoto, K
    • Journal Title

      American Journal of Physiology, Gastrointestinal and Liver Physiology 297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Journal Article] MGM-9 [(E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate], a derivative of the indole alkaloid mitragynine: a novel dual-acting mu- and kappa-opioid agonist with potent antinociceptive and weak rewarding effects in mice2008

    • Author(s)
      松本健次郎, 他11名
    • Journal Title

      Neuropharmacology 54

      Pages: 154-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Journal Article] Validation of 13C-acetic acid breath test by measuring effects of loperamide, morphine, mosapride, and itopride on gastric emptying in mice2008

    • Author(s)
      Matsumoto, K.
    • Journal Title

      Biological and Pharmaceutical and Bulletin 31

      Pages: 1917-1922

    • NAID

      110006936334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Journal Article] MGM-9[(E)-methyl 2-(3-ethyl-7a, 12a-(epoxyethanoxy)-9-fluoro-1, 2, 3, 4, 6, 7, 12, 12b-octahydro-8- methoxyindolo[2, 3-a]quinolizin-2-y1) -3-methoxyacrylatel, a derivative of the indole alkaloid mitragynine : a novel dual-acting mu- and kappa-opioid agonist with potent antinociceptive and weak rewarding effects in2008

    • Author(s)
      Matsumoto, K.
    • Journal Title

      Neuropharmacology 54

      Pages: 154-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Journal Article] Partial agonistic effects of 9-hydroxycorynantheidine on μ-opioid receptor in the guinea-pig ileum2006

    • Author(s)
      Matsumoto, K.
    • Journal Title

      Life Sciences 78・19

      Pages: 2265-2271

    • Data Source
      KAKENHI-PROJECT-18790126
  • [Journal Article] Antinociception and inhibition of gastrointestinal transit by 7-hydroxymitragynine isolated from Thai herbal medicine Mitragyna speciosa through μ-opioid receptors2006

    • Author(s)
      Matsumoto, K.
    • Journal Title

      European Journal of Pharmacology 549・1-3

      Pages: 63-70

    • Data Source
      KAKENHI-PROJECT-18790126
  • [Patent]2008

    • Inventor(s)
      高山廣光、北島満里子、堀江俊治、松本健次郎
    • Industrial Property Rights Holder
      国立大学法人 千葉大学学校法人 城西大学
    • Filing Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Patent] オピオイド鎮痛剤2008

    • Inventor(s)
      高山廣光, 北島満里子, 堀江俊治, 松本健次郎
    • Industrial Property Rights Holder
      国立大学法人千葉大学学校法人城西大学
    • Filing Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Patent] Indole alkaloid derivatives having opioid receptor agonistic effect, and therapeutic compositions and methods relating same2007

    • Inventor(s)
      高山 廣光, 北島 満里子, 堀江 俊治, 松本 健次郎
    • Industrial Property Rights Holder
      国立大学法人千葉大学 学校法人城西大学
    • Filing Date
      2007-11-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18790126
  • [Patent] オピオイド鎮痛剤2007

    • Inventor(s)
      高山 廣光, 北島 満里子, 堀江 俊治, 松本 健次郎
    • Industrial Property Rights Holder
      国立大学法人千葉大学 学校法人城西大学
    • Industrial Property Number
      2007-310939
    • Filing Date
      2007-11-30
    • Data Source
      KAKENHI-PROJECT-18790126
  • [Presentation] 消化管炎症関連内蔵痛覚過敏における TRPチャネルの関与2023

    • Author(s)
      松本 健次郎、加藤 伸一
    • Organizer
      日本薬学会第143年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06656
  • [Presentation] マウス若齢期社会的敗北ストレスを用いた 新規過敏性腸症候群様モデルの確立2021

    • Author(s)
      松本健次郎、堀江俊治、加藤伸一
    • Organizer
      第48回日本潰瘍学会
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] マウス若齢期社会的敗北ストレスを用いた 新規過敏性腸症候群様モデルの確立2021

    • Author(s)
      松本 健次郎、堀江 俊治2、加藤 伸一
    • Organizer
      第48回日本潰瘍学会
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] におけるTRPV2、TRPV1発現とTNBS誘起内臓痛覚過敏における役割の解明2021

    • Author(s)
      松本健次郎、加藤伸一
    • Organizer
      第23回日本神経消化器病学会
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] マウス若齢期社会的敗北ストレスによる、過敏性腸症候群様の病態と腸内細菌叢の変化2021

    • Author(s)
      松本健次郎
    • Organizer
      第23回日本神経消化器病学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] ラット食道炎モデルの病態におけるTransient Receptor Potential Vanilloid 2 (TRPV2)の関与2020

    • Author(s)
      松本 健次郎、末永 美奈子、林 大成、 中本 智大、 安田 浩之、加藤 伸一
    • Organizer
      第22回神経消化器病学会
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] 難治性消化管疾患モデル動物におけるTRPV2の発現と機能解析2020

    • Author(s)
      松本 健次郎,末永 美奈子, 林 大成, 城戸 瑞穂,加藤 伸一
    • Organizer
      2020TRP研究会
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] ROLE OF TRANSIENT RECEPTOR POTENTIAL VANILLOID SUBTYPE 2 IN LOWER ESOPHAGEAL SPHINCTER IN RAT REFLUX ESOPHAGITIS2020

    • Author(s)
      Kenjiro Matsumoto, Shinichi Kato
    • Organizer
      Digestive Disease Week 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] Role of TRPM8 in the irritable bowel syndrome like symptoms induced by early-childhood social defeat stress in mice2020

    • Author(s)
      Kenjiro Matsumoto, Makoto Tominaga, Syunji Horie, Shinichi Kato
    • Organizer
      he 10th Takeda Science Foundation Symposium on PharmaSciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07109
  • [Presentation] Involvement of transient receptor potential vanilloid (TRPV4) in the regulation of murine colitis and colitis-associated cancer model2019

    • Author(s)
      松本 健次郎、加藤 伸一
    • Organizer
      日本薬理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] マウスIBD関連大腸がんの病態における 温度感受性TRPV4チャネルの役割2018

    • Author(s)
      松本 健次郎、天ヶ瀬 紀久子、 加藤 伸一
    • Organizer
      日本潰瘍学会
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] 幼少期マウス社会的敗北ストレスを用いた、過敏性腸症候群モデルの検討2018

    • Author(s)
      松本 健次郎、堀江 俊治、加藤 伸一
    • Organizer
      神経消化器病学会
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] マウス大腸炎および大腸炎関連発がんにおける血管内皮細胞発現TRPV4の関与2017

    • Author(s)
      松本健次郎、天ヶ瀬紀久子、加藤伸一
    • Organizer
      第35回サイトプロテクション研究会
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] 大腸炎および大腸炎関連発癌における血管内皮TRPV4の関与2017

    • Author(s)
      松本健次郎、内海大知、天ヶ瀬紀久子、富永真琴、加藤伸一
    • Organizer
      日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] マウス大腸炎、大腸炎関連がんモデルにおける、TRPV4チャネルの機能2017

    • Author(s)
      深見安希、松本健次郎、内海大知、天ヶ瀬紀久子、富永真琴、加藤伸一
    • Organizer
      日本薬学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] TNBS誘起内臓痛覚過敏、術後麻痺性イレウスの病態におけるTRPM2の機能解析2017

    • Author(s)
      松本健次郎、堀 正敏、堀江俊治、天ヶ瀬紀久子、尾崎 博、森 泰生、加藤伸一
    • Organizer
      第13回TRPチャネル研究会
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) Regulates Vascular Endothelial Permeability during Colonic Inflammation in Dextran Sulfate Sodium (DSS)-induced Murine Colitis2017

    • Author(s)
      Kenjiro Matsumoto, Daichi Utsumi, Kikuko Amagase, Makoto Tominaga, Shinichi Kato
    • Organizer
      Experimental Biology 2017
    • Place of Presentation
      Chicago
    • Year and Date
      2017-04-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] 1.松本健次郎 難治性消化管疾患の病態制御における温度感受性TRPチャネルおよびセロトニン5-HT3受容体の役割解明2017

    • Author(s)
      松本健次郎
    • Organizer
      生体機能と創薬シンポジウム2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] Transient receptor potential vanilloid 4 (TRPV4) regulates vascular endothelial permeability during colonic inflammation in dextran sulfate sodium-induced murine colitis.2017

    • Author(s)
      Matsumoto K, Utsumi D, Amagase K, Tominaga M, Kato S.
    • Organizer
      Experimental Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] ラット消化管におけるTRPM2チャネルの発現とTNBS誘起内臓痛覚過敏との関与2016

    • Author(s)
      大谷 彩、松本健次郎、田嶋公人、天ヶ瀬紀久子、堀江俊治、加藤伸一
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) Regulates Vascular Endothelial Permeability during Colonic Inflammation in Dextran Sulfate Sodium (DSS)-induced Murine Colitis2016

    • Author(s)
      Kenjiro Matsumoto, Daichi Utsumi, Kikuko Amagase, Makoto Tominaga, Shinichi Kato
    • Organizer
      Digestive Weeks 2016
    • Place of Presentation
      San Diego
    • Year and Date
      2016-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08287
  • [Presentation] TRPM2チャネルの発現とTNBS誘起ラット内臓痛覚過敏との関与2015

    • Author(s)
      宮本明日香、松本健次郎、天ヶ瀬紀久子、堀江俊治、加藤伸一
    • Organizer
      第65回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Presentation] ラット腸管神経系、脊髄後根神経節におけるTRPM2チャネルの局在に関する免疫組織化学的検討2013

    • Author(s)
      松本 健次郎,渡辺 智章,五十幡 陽, 高木 加奈子, 田嶋 公人, 堀江 俊治
    • Organizer
      TRP研究会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Presentation] Distribution of transient receptor potential melastatin 2 channels-expressing nerve fibers in rat alimentary tract and dorsal root ganglion.2013

    • Author(s)
      Kenjiro Matsumoto, Tomoaki Watanabe, Minami Isohata, Kimihito Tashima, Syunji Horie
    • Organizer
      Digestive Disease Week 2013
    • Place of Presentation
      Orland
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Presentation] マウス下部消化管におけるTRPV1発現神経の分布と神経ペプチド,セロトニン,NO合成酵素の局在に関する免疫組織学的検討2010

    • Author(s)
      松本健次郎
    • Organizer
      第6回日本消化管学会
    • Place of Presentation
      福岡
    • Year and Date
      2010-02-20
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] マウス下部消化管におけるTRPV1発現神経と神経ペプチドとの局在に関する免疫組織学的検討2009

    • Author(s)
      松本健次郎
    • Organizer
      第11回日本神経消化器病学会
    • Place of Presentation
      仙台
    • Year and Date
      2009-09-25
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] Immunohistochemical characterization of transient receptor potential vanilloid (TRPV) 1 and sensory neuropeptides in mouse rectum : clear differences of the subpopulations in mucosal, submucosal and muscle layer2009

    • Author(s)
      松本健次郎
    • Organizer
      Digestive Disease Week and the 109th Annual Meeting of the American Gastroenterological Association Institute
    • Place of Presentation
      米国・シカゴ
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] マウス下部消化管におけるTRPV1発現神経と神経ペプチドとの局在に関する免疫組織学的検討2009

    • Author(s)
      松本健次郎
    • Organizer
      日本神経消化器病学会
    • Place of Presentation
      仙台
    • Year and Date
      2009-09-21
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] マウス直腸におけるTRPV1発現神経と神経ペプチドの局在に関する免疫組織学的検討2009

    • Author(s)
      松本健次郎
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] Differences in localization of TRPV1 channels and contractile effect of capsaicin in mouse isolated lower gastrointestinal tract: higher abundance and sensitivity of TRPV1 channels in rectum and distal colon than in transverse and proximal colon2008

    • Author(s)
      松本健次郎
    • Organizer
      Digestive Disease Week and the 109th Annual Meeting of the American Gastroenterological Association Institute
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2008-05-21
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] マウス13^C酢酸呼気テストを用いた、ロペラミド、モルヒネ、モサプリドの胃運動に対する作用の評価2008

    • Author(s)
      松本 健次郎
    • Organizer
      第4回日本消化管学会総会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-02-08
    • Data Source
      KAKENHI-PROJECT-18790126
  • [Presentation] マウス摘出下部消化管におけるバニロイド受容体TRPV1の局在とカプサイシン誘起平滑筋収縮作用機序の解明2008

    • Author(s)
      松本健次郎
    • Organizer
      生体機能と創薬シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-09-05
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] TRPV1発現知覚神経を介するマウス下部消化管におけるタキキニン類の関与2008

    • Author(s)
      松本 健次郎
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-18790126
  • [Presentation] Differences in localization of TRPV1 channels and contractile effect of capsaicin in mouse isolated lower gaRtrointestinal trant7 higher al-mndanne and sensitivity of TRPV1 rhannp1R in reetnm2008

    • Author(s)
      松本健次郎
    • Organizer
      Digestive Disease Week and the 109th Annual Meeting of the American Ga
    • Place of Presentation
      米国・サンディエゴ
    • Year and Date
      2008-05-21
    • Data Source
      KAKENHI-PROJECT-20790075
  • [Presentation] タイ王国麻薬性薬用植物Mitragyna spedosaアルカロイドとモルヒネの鎮痛作用と精神依存性形成能の評価2007

    • Author(s)
      松本 健次郎
    • Organizer
      第1回緩和医療学会
    • Place of Presentation
      東京
    • Year and Date
      2007-10-21
    • Data Source
      KAKENHI-PROJECT-18790126
  • [Presentation] MGM-9, a derivative of indole alkaloid, mitragynine: a novel μ・ and κ・opioid agonist with potent antinociceptive and weak rewarding effects in mice.2007

    • Author(s)
      松本 健次郎
    • Organizer
      International Narcotic Research Conference, Symposium Lecture
    • Place of Presentation
      ドイツ・ベルリン
    • Year and Date
      2007-07-12
    • Data Source
      KAKENHI-PROJECT-18790126
  • [Presentation] 大腸炎モデルラットの内臓痛覚過敏状態における

    • Author(s)
      松本 健次郎, 田嶋 公人, 天ヶ瀬紀久子, 加藤 伸一, 堀江 俊治
    • Organizer
      日本潰瘍学会
    • Place of Presentation
      東京
    • Year and Date
      2014-10-31 – 2014-11-01
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Presentation] 炎症性腸疾患モデル動物の内臓痛覚過敏状態におけるTRPM8チャネルの機能

    • Author(s)
      松本 健次郎,細谷 拓司,田嶋 公人,天ヶ瀬 紀久子,加藤 伸一,堀江俊治
    • Organizer
      TRP研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-06-05 – 2014-06-06
    • Data Source
      KAKENHI-PROJECT-25860395
  • [Presentation] Role of Transient Receptor Potential Melastatin 2 (TRPM2) Channels in Visceral Pain and Hypersensitivity in Rats

    • Author(s)
      Kenjiro Matsumoto, Kimihito Tashima, Shinichi Kato, Syunji Horie
    • Organizer
      Digestive Disease Week 2014
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2014-05-04 – 2014-05-06
    • Data Source
      KAKENHI-PROJECT-25860395
  • 1.  KATO SHINICHI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 2.  TOMINAGA MAKOTO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 3.  堀江 俊治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 4.  天ヶ瀬 紀久子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  田嶋 公人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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