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SHINBO Toshihiro  新保 年弘

ORCIDConnect your ORCID iD *help
Researcher Number 10406910
Affiliation (based on the past Project Information) *help 2012: 東京工科大学, 公私立大学の部局等, 助教
2011: 東京工科大学, 医療保健学部, 助教
2008 – 2011: Kitasato University, 医療衛生学部, 助教
Review Section/Research Field
Principal Investigator
Emergency medicine / Thoracic surgery
Except Principal Investigator
Kidney internal medicine / Respiratory organ internal medicine
Keywords
Principal Investigator
リンパ球 / 体外循環 / 人工心肺
Except Principal Investigator
超小型透析システム / マウス透析システム / 血小板活性化 / 一酸化窒素ガス / 血液透析膜 / 生体適合性 / 人工透析学 … More / 活性酵素 / 一酸化窒素 / 水素 / 活性酸素 / 酸素 / 肺障害 / 酸素障害 / その他・酸素障害 / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (5 People)
  •  急性心筋梗塞再灌流障害における水素・一酸化窒素併用吸入療法の検討Principal Investigator

    • Principal Investigator
      新保 年弘
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokyo University of Technology
  •  The effects of hydrogen gas breathing on the lung injury induced by hyperoxia

    • Principal Investigator
      KOBAYASHI Hirosuke
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kitasato University
  •  Improvement of biocompatibility of dialysis membrane by nitric oxide or hydrogen

    • Principal Investigator
      KOKUBO Kenichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kitasato University
  •  Study of optimization of extracorporeal circulation in open heart surgery on diminished immune functionPrincipal Investigator

    • Principal Investigator
      SHINBO Toshihiro
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kitasato University

All 2012 2011 2010

All Journal Article Presentation Patent

  • [Journal Article] X-ray radiation causes electromagnetic interference in implantable cardiac pacemakers2010

    • Author(s)
      Hirose M, Tachikawa K, Ozaki M, Umezawa N, Shinbo T, Kokubo K, Kobayashi H
    • Journal Title

      Pacing Clin Electrophysiol

      Volume: 33 Pages: 1174-1181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Journal Article] Removal of an endotoxin fragment(Lipid A) by an endotoxin-retentive filter2010

    • Author(s)
      Kokubo K, Futatsugi K, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Journal Title

      Desalination and Water Treatment

      Volume: 17 Pages: 25-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Journal Article] Respiratory Rhythms in Healthy Subjects and Patients2010

    • Author(s)
      Shimane M, Tomita Y, Shinbo T, Kokubo K, Hirose M, Hataishi R, Kubota M, Masuda N, Kobayashi H
    • Journal Title

      Advances in Experimental Medicine & Biology

      Volume: 662 Pages: 133-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Journal Article] Macrophages that survive hyperoxia exposure have higher superoxide dismutase activities in their mitochondria2010

    • Author(s)
      Kokubo K, Soeda S, Shinbo T, Hirose M, Fuku N, Nishigaki Y, Tanaka M, Kobayashi H
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 63-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Patent] 虚血再潅流障害軽減用治療剤および治療装置2010

    • Inventor(s)
      小林弘祐,小久保謙一,新保年弘
    • Industrial Property Rights Holder
      学校法人北里研究所
    • Industrial Property Number
      2010-053405
    • Filing Date
      2010-03-10
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Patent] 虚血再潅流障害軽減用治療剤および治療装置2010

    • Inventor(s)
      小林弘祐、小久保謙一、新保年弘
    • Industrial Property Rights Holder
      学校法人北里研究所
    • Industrial Property Number
      2010-053405
    • Filing Date
      2010-03-10
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Dialysate containing nitric oxide suppresses platelet activation on the surface of dialysis membrane2012

    • Author(s)
      Kokubo K, Urabe S, Hanada S, Ebine T, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      7th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh, UK
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] 心筋虚血-再灌流障害に対する水素・一酸化窒素併用吸入の効果2012

    • Author(s)
      佐藤友理, 新保年弘, 畑石隆治, 小久保謙一, 廣瀬稔, 小林弘祐
    • Organizer
      第2回分子状水素医学シンポジウム
    • Place of Presentation
      北里大学白金キャンパス(東京)
    • Year and Date
      2012-02-11
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Suppression of platelet activation on the surface of dialysis membrane using nitric oxide containing dialysate2011

    • Author(s)
      Urabe S, Kokubo K, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      47th ERA-EDTA Congress
    • Place of Presentation
      Prague, Czech republic
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] 一酸化窒素供与体を用いた血液透析における血小板凝集の抑制2011

    • Author(s)
      浦辺俊一郎, 小久保謙一, 塚尾浩, 新保年弘, 廣瀬稔, 小林弘祐
    • Organizer
      日本医工学治療学会第27回学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] 一酸化窒素供与体を用いた血液透析における血小板凝集の抑制2011

    • Author(s)
      浦辺俊一郎, 小久保謙一, 塚尾浩, 新保年弘, 廣瀬稔, 小林弘祐
    • Organizer
      日本医工学治療学会第27回学術大会
    • Place of Presentation
      岡山コンベンションセンター(岡山)
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] 誤嚥性肺炎マウスモデルにおける肺障害および遠隔臓器障害への水素吸入の効果2011

    • Author(s)
      畑石隆治, 西川優希, 新保年弘, 佐藤友里, 野田健太郎, 小久保謙一, 益田典幸, 小林弘祐
    • Organizer
      第5回iPUC-II (Integrated Pulmonary Circulation Research-II)
    • Place of Presentation
      東京ステーションコンファレンス(東京)
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Increased surface coverage area of polyvinylpyrrolidone on polysulfone hemofilter membrane improves biocompatibility by suppressing cell adhesion during continuous hemofiltration2011

    • Author(s)
      Kurihara Y, Kokubo K, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      16th International Conference on Continuous Renal Replacement Therapies CRRT2001
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Suppression of platelet activation on the surface of dialysis membrane using nitric oxide containing dialysate2011

    • Author(s)
      Urabe S, Kokubo K, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      47^<th> ERA-EDTA Congress
    • Place of Presentation
      Prague Congress Centre (Prague, Czech republic)
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] Urea concentrating ability of artificial renal tubule based on countercurrent multiplier system using electrodialysis, dialysis and filtration2010

    • Author(s)
      Harashima T, Otani Y, Kokubo K, Tsukao H, Shinbo T, Hirose M, Sakai K, Kobayashi H
    • Organizer
      World Conference on portable-wearable and miniaturized systems for dialysis and ultrafiltration and 3rd Annual Congress of the International Society for hemodialysis
    • Place of Presentation
      Vicenza, Italy
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Simultaneous inhalation of nitric oxide and hydrogen reduces infarct size in the mouse model of myocardial ischemia-reperfusion injury2010

    • Author(s)
      Shinbo T, Sato Y, Hataishi R, Kokubo K, Hirose M, Kobayashi H
    • Organizer
      6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Dialysis membrane releasing nitric oxide from dialysate side increases cyclic guanosine monophosphate in platelets and suppresses the activation of platelets on the surface2010

    • Author(s)
      Kokubo K, Urabe S, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Dialysis membrane releasing nitric oxide from dialysate side increases cyclic guanosine monophosphate in platelets and suppresses the activation of platelets on the surface.2010

    • Author(s)
      Kenichi Kokubo, Shunichiro Urabe, Hiroshi Tsukao, Toshihiro Shinbo, Minoru Hirose, Hirosuke Kobayashi
    • Organizer
      6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      国立京都国際会館,京都
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] Activation of platelets in contact with oxidized vitamin E-coated surface2010

    • Author(s)
      Tsukao H, Kokubo K, Nagasato M, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      47th ERA-EDTA Congress
    • Place of Presentation
      Munich
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Inhaled hydrogen during mechanical ventilation and hydrogen generated by enterobacterial flora reduce infarct size in the mouse model of myo-cardial ischemia-reperfusion injury.2010

    • Author(s)
      Sato Y, Shinbo T, Hataishi R, Kokubo K, Hirose M, Kobayashi H.
    • Organizer
      European Respiratory Society Annual Congress 2010
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Suppression of platelet Activation on the surface of dialysis membrane releasing nitric oxide from the dialysate2010

    • Author(s)
      Urabe S, Kokubo K, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      47th ERA-EDTA Congress
    • Place of Presentation
      Munich
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] Simultaneous inhalation of nitric oxide and hydrogen reduces infarct size in the mouse model of myocardial ischemia- reperfusion injury.2010

    • Author(s)
      Shinbo T, Sato Y, Hataishi R, Kokubo K, Hirose M, Kobayashi H
    • Organizer
      6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      国際会館(Kyoto)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Dialysate-based perfusate of low viscosity is suitable for normothermic ex vivo lung perfusion2010

    • Author(s)
      Noda K, Kokubo K, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      ERS Annual Congress 2010
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Differentiation of side population cells isolated from human amniotic mesenchymal cell into vascular endothelial cells under hypoxic condition2010

    • Author(s)
      Maruyama N, Nishikubo Y, Kokubo K, Shinbo T, Hirose M, Kobayashi M, Sakuragawa N, Kobayashi H
    • Organizer
      Tissue Engineering & Regenerative Medicine International Society 2010 Asia Pacific meeting, TERMIS-AP 2010 Annual Conference
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Dialysis membrane releasing nitric oxide from dialysate side increases cyclic guanosine monophosphate in platelets and suppresses the activation of platelets on the surface2010

    • Author(s)
      Kokubo K, Urabe S, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21591060
  • [Presentation] Differentiation into neural cells from human amniotic mesenchymal cell in serum free medium2010

    • Author(s)
      Nishikubo Y, Maruyama N, Kokubo K, Shinbo T, Hirose M, Kobayashi M, Sakuragawa N, Kobayashi H
    • Organizer
      Tissue Engineering & Regenerative Medicine International Society 2010 Asia Pacific meeting, TERMIS-AP 2010 Annual Conference
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Hydrogen protects alveolar epithelial cells(A549)against injury induced by reactive oxygen species in vitro.2010

    • Author(s)
      Kokubo K, Yamashita K, Shinbo T, Hirose M, Kobayashi H.
    • Organizer
      European Respiratory Society Annual Congress 2010
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Inhaled hydrogen during mechanical ventilation and hydrogen generated by enterobacterial flora reduce infarct size in the mouse model of myocardial ischemia-reperfusion injury2010

    • Author(s)
      Sato Y, Shinbo T, Hataishi R, Kokubo K, Hirose M, Kobayashi H
    • Organizer
      European Respiratory Society Annual Congress 2010
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Suppression of platelet Activation on the surface of dialysis membrane releasing nitric oxide from the dialysate2010

    • Author(s)
      Urabe S, Kokubo K, Tsukao H, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      47th ERA-EDTA Congress
    • Place of Presentation
      Munich
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Hydrogen protects alveolar epithelial cells(A549) against injury induced by reactive oxygen species in vitro2010

    • Author(s)
      Kokubo K, Yamashita K, Shinbo T, Hirose M, Kobayashi H
    • Organizer
      European Respiratory Society Annual Congress 2010
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21591002
  • [Presentation] Suppression of platelet Activation on the surface of dialysis membrane releasing nitric oxide from the dialysate.2010

    • Author(s)
      Shunichiro Urabe, Kenichi Kokubo, Hiroshi Tsukao, Toshihiro Shinbo, Minoru Hirose, Hirosuke Kobayashi
    • Organizer
      47^<th> ERA-EDTA Congress
    • Place of Presentation
      International Congress Centre Munich, Munich, Germany
    • Data Source
      KAKENHI-PROJECT-21591060
  • 1.  KOBAYASHI Hirosuke (70153632)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 2.  KOKUBO Kenichi (20287965)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 3.  HIROSE Minoru (50286382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results
  • 4.  KUBOTA Masaru (00234500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  HATAISHI Ryuji (20276124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results

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