KOBAYASHI Hideyuki 小林秀行

… Alternative Names

小林秀行コバヤシヒデユキ

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Researcher Number	10408875
Affiliation (Current)	2025: 東邦大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 東邦大学, 医学部, 准教授 2016 – 2023: 東邦大学, 医学部, 准教授 2014: 東邦大学, 医学部, 准教授 2012 – 2013: 東邦大学, 医学部, 講師 2008 – 2009: Toho University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator 男性不妊症 / 無精子症 / 幹細胞 / AI / micro TESE / iPS / 男性不妊 / 細胞・組織 / 再生医学 / 予測分析 … More / 非閉塞性無精子症 / 予測診断 / ホルモン検査 / 精液検査 / ミトコンドリア / Google Cloud / AutoML / testis / pathology / machine learning / artificial intelligence / azoospermia / 精巣組織 / 精索静脈瘤 / Johnsen score / AZF / マイクロミニピッグ / iPS細胞 / mini-pig / 精子幹細胞 / 精子 … More Except Principal Investigator 泌尿器癌 / 腎細胞癌 / 尿路上皮癌 / 前立腺癌 / Versikine / Versican / 癌免疫治療 / 泌尿器がん / VCAN / 抗がん剤治療 / がん免疫治療 Less

唾液によるホルモン測定に基づいた男性不妊AIリスク判定モデルの構築Principal Investigator
- Principal Investigator
  
  小林秀行
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Toho University
AI（人工知能）技術を活用した男性不妊症の新規診断法および治療法の開発Principal Investigator
- Principal Investigator
  
  小林秀行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Toho University
泌尿器癌の腫瘍免疫におけるVCANの役割の解明と免疫療法への応用
- Principal Investigator
  
  三井要造
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Toho University
Elucidation of the pathology of varicocele and development of new treatments through analysis of sperm mitochondriaPrincipal Investigator
- Principal Investigator
  
  Kobayashi Hideyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Toho University
Elucidation of male infertility by epigenome analysis of iPS cells derived from male infertility and stem cell researchPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Hideyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Toho University
The breakthrough of male infertily by stem cell researchPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Hideyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Toho University
Identification and analysis of human spermatogonial stem cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Hideyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Toho University

All 2023 2022 2021 2017 2014 2013 2009 2008 Other

All Journal Article Presentation Book Patent

[Book] Pluripotent Stem Cells2013
- Author(s)
  Kobayashi H, Nagao K, Nakajima K
- Publisher
  In Tech
- Data Source
  KAKENHI-PROJECT-24791674
[Journal Article] Urine pH and imaging findings of prostate useful predictors of prolonged duration of hematospermia2023
- Author(s)
  Mitsui Yozo、Yamabe Fumito、Hori Shunsuke、Uetani Masato、Aoki Hiroshi、Sakurabayashi Kei、Okawa Mizuho、Kobayashi Hideyuki、Nagao Koichi、Nakajima Koichi
- Journal Title
  
  Translational Andrology and Urology
  
  Volume: 12 Issue: 7 Pages: 1090-1100
- DOI
  10.21037/tau-23-108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09513
[Journal Article] Combination of C-reactive protein/albumin ratio and time to castration resistance enhances prediction of prognosis for patients with metastatic castration-resistant prostate cancer2023
- Author(s)
  Mitsui Yozo、Yamabe Fumito、Hori Shunsuke、Uetani Masato、Aoki Hiroshi、Sakurabayashi Kei、Okawa Mizuho、Kobayashi Hideyuki、Nagao Koichi、Nakajima Koichi
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 13 Pages: 1162820-1162820
- DOI
  10.3389/fonc.2023.1162820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09513
[Journal Article] AI Model Developed Using Machine Learning for Predicting Sperm Retrieval in Micro-TESE for Nonobstructive Azoospermia Patients2023
- Author(s)
  Kobayashi Hideyuki、Uetani Masato、Yamabe Fumito、Mitsui Yozo、Nakajima Koichi、Nagao Koichi
- Journal Title
  
  Andrologia
  
  Volume: 2023 Pages: 1-10
- DOI
  10.1155/2023/5693116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09486
[Journal Article] Molecular Mechanisms and Risk Factors Related to the Pathogenesis of Peyronie’s Disease2023
- Author(s)
  Mitsui Yozo、Yamabe Fumito、Hori Shunsuke、Uetani Masato、Kobayashi Hideyuki、Nagao Koichi、Nakajima Koichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 12 Pages: 10133-10133
- DOI
  10.3390/ijms241210133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09513
[Journal Article] Longitudinal change in castration-resistant prostate cancer biomarker AST/ALT ratio reflects tumor progression2023
- Author(s)
  Mitsui Yozo、Yamabe Fumito、Hori Shunsuke、Uetani Masato、Aoki Hiroshi、Sakurabayashi Kei、Okawa Mizuho、Kobayashi Hideyuki、Nagao Koichi、Nakajima Koichi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 15292-15292
- DOI
  10.1038/s41598-023-42711-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09513
[Journal Article] A method for utilizing automated machine learning for histopathological classification of testis based on Johnsen scores2021
- Author(s)
  Ito Yurika、Unagami Mami、Yamabe Fumito、Mitsui Yozo、Nakajima Koichi、Nagao Koichi、Kobayashi Hideyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 9962-9962
- DOI
  10.1038/s41598-021-89369-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09701
[Journal Article] Derivation of Induced Pluripotent Stem (iPS)-like Cells from Microminipig Somatic Cells by Sendai Viral Transduction of 4 HumanG, OCT4, SOX2, KLF4, and c-MYC2017
- Author(s)
  Yamabe F, Nagao K, Nakajim K, Kobayashi H
- Journal Title
  
  Journal of Veterinary Science & Animal Husbandry
  
  Volume: 5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K11072
[Journal Article] The Minipig-A new tool in stem cell research.2014
- Author(s)
  Kobayashi H, Tai T, Nagao K, Nakajima K:
- Journal Title
  
  Plulripotent stem cell biology advances in mechanisms, methods and models.
  
  Volume: １ Pages: 198-209
- DOI
  10.5772/57603
- ISBN
  9789535115908
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24791674
[Journal Article] Thy-1+ cells isolated from adult human testicular tissues express human embryonic stem cell genes OCT3/4 and NANOG and may include spermatogonial stem cells2009
- Author(s)
  Hideyuki Kobayashi
- Journal Title
  
  Reproductive Medicine and Biology Volume 8
  
  Pages: 71-77
- NAID
  10025380991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791127
[Journal Article] Thy-1+ cells isolated from adult human testicular tissues express human embryonic stem cell genes OCT3/4 and NANOG and may include spermatogonial stem cells2009
- Author(s)
  Kobayashi H, Nagao K, Nakajima K, Miura K, Ishii N
- Journal Title
  
  Reproductive Medicine and Biology Volume8
  
  Pages: 71-77
- NAID
  10025380991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791127
[Patent] 男性不妊症のリスク特定方法2023
- Inventor(s)
  小林秀行
- Industrial Property Rights Holder
  学校法人東邦大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-065013
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K09486
[Presentation] AI model developed using machine learning to determine possibility of sperm retrieval in micro TESE for non-obstructive azoospermia.2023
- Author(s)
  小林　秀行
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K09701
[Presentation] A novel prediction model for possibility of sperm retrieval in micro TESE for non-obstructive azoospermia patients using automated artificial intelligence2023
- Author(s)
  Kobayashi H
- Organizer
  118rd Annual Meeting of American Urological Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09701
[Presentation] Association between numbers of ligated veins, arteries, lymphatics, and nerves in spermatic cord during varicocelectomy and semen parameters2023
- Author(s)
  Kobayashi H
- Organizer
  20th Urological Association of Asia Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09701
[Presentation] 男性不妊症のリスクを血液検査から予測するAIモデル2023
- Author(s)
  小林　秀行、上谷　将人、竹内　晋次郎、永尾　光一
- Organizer
  第68回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-22K09486
[Presentation] ノーコードが実現する男性不妊症の未来2022
- Author(s)
  小林秀行
- Organizer
  第67回日本生殖医学会学術講演会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09486
[Presentation] 非閉塞性無精子症患者に対するmicro TESEの術前に精子回収を予測できるAIモデルの開発2022
- Author(s)
  小林秀行
- Organizer
  第67回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-22K09486
[Presentation] 男性不妊症におけるAI研究の取り組み2022
- Author(s)
  小林秀行
- Organizer
  第21回生殖バイオロジー東京シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K09486
[Presentation] 男性不妊症における医療DXの取り組み2022
- Author(s)
  小林秀行
- Organizer
  第23回横浜ART研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09486
[Presentation] 正診率99.5%の無精子症における精巣病理診断AIモデルの開発2021
- Author(s)
  小林秀行
- Organizer
  第66回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-19K09701
[Presentation] 画像認識AIによるJohnsen scoreの自動判別モデルの構築2021
- Author(s)
  小林秀行
- Organizer
  第109回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K09701
[Presentation] マイクロミニブタ由来iPS細胞のin vitroにおける組織分化の検討2014
- Author(s)
  小林　秀行
- Organizer
  第10２回日本泌尿器科学会総会
- Place of Presentation
  神戸国際会議場（神戸市中央区）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-24791674
[Presentation] 無精子症患者における精巣組織のゲノムワイドなDNAメチル化パターンについての検討2014
- Author(s)
  小林　秀行
- Organizer
  第33回日本アンドロロジー学術総会
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県北佐久郡）
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-24791674
[Presentation] 当院におけるMicroTESEの実際2014
- Author(s)
  小林　秀行
- Organizer
  第59回日本生殖医学会学術講演会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2014-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-24791674
[Presentation] 精子再生への取り組み～精原幹細胞のこれからの可能性～2014
- Author(s)
  小林　秀行
- Organizer
  第32回日本受精着床学会総会
- Place of Presentation
  ハイアットリージェンシー東京（東京都新宿区）
- Year and Date
  2014-08-01
- Invited
- Data Source
  KAKENHI-PROJECT-24791674
[Presentation] 閉塞性無精子症と非閉塞性無精子症における精巣組織のDNAメチル化パターンについての検討2014
- Author(s)
  小林　秀行
- Organizer
  第59回日本生殖医学会学術講演会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-24791674
[Presentation] ヒト精巣組織からのヒト精子幹細胞human spermatogonial stem cells(SSCs)の分離及び培養の試み2008
- Author(s)
  小林秀行
- Organizer
  第96回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-04-27
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] The isolation, characterization, and function of male germline stem cells obtained from human testicular tissue2008
- Author(s)
  小林秀行
- Organizer
  103th Annual meeting, of the American Urological Association
- Place of Presentation
  オーランド(アメリカ)
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] ヒト精巣組織からのヒト精子幹細胞human spermatogonial stem cells(SSCs)の分離の試み及び機能解析2008
- Author(s)
  小林秀行
- Organizer
  第53回日本生殖医学会総会
- Place of Presentation
  神戸
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] ヒト精巣組織か照のヒト精子幹細胞human spermatogonial stem cells(SSCs)の分離及び培養の試み2008
- Author(s)
  小林秀行
- Organizer
  第96回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-04-27
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] ヒト精巣組織からのヒト精子幹細胞human spermatogonial stem cells(SSCs)の分離の試み2008
- Author(s)
  小林秀行
- Organizer
  第27回日本アンドロロジー学会総会
- Place of Presentation
  京都
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] The characterization and function of male germline stem cells obtained from human testicular tissue2008
- Author(s)
  小林秀行
- Organizer
  64th Annual meeting of the American Society for Reproductive Medicine
- Place of Presentation
  サンフランシスコ(アメリカ)
- Year and Date
  2008-11-11
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] The isolation, characterization, and function of male germline stem cells obtained from human testicular tissue2008
- Author(s)
  小林秀行
- Organizer
  67^<th> Annual meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] The isolation, characterization, and function of male germline stem cells obtained from human testicular tissue2008
- Author(s)
  小林秀行
- Organizer
  67th Annual meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] The isolation, characterization, and function of male germline stem cells obtained from human testicular tissue2008
- Author(s)
  小林秀行
- Organizer
  103th Annual meeting of the American Urological Association
- Place of Presentation
  オーランド(アメリカ)
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-20791127
[Presentation] センダイウイルスを用いたマイクロミニブタiPS細胞の誘導
- Author(s)
  小林秀行，小磯泰裕, 鵜木勉, 青木洋, 清水俊博, 中島陽太、永田雅人, 山辺史人，上村修一，田中祝江，鈴木九里，永尾光一，中島耕一
- Organizer
  第32回日本アンドロロジー学術総会
- Place of Presentation
  グランキューブ大阪（大阪）
- Data Source
  KAKENHI-PROJECT-24791674
[Presentation] 薬剤性誘導レンチウイルスを用いたヒト精巣由来繊維芽細胞からのiPS細胞の誘導
- Author(s)
  小林秀行，松井幸英, 中島陽太, 岡祐輔, 田井俊宏, 山辺史人，高杉啓一郎，上村修一，田中祝江，鈴木九里，永尾光一，中島耕一
- Organizer
  第101回日本泌尿器科学会総会
- Place of Presentation
  さっぽろ芸術文化の館他（北海道）
- Data Source
  KAKENHI-PROJECT-24791674

1. 三井要造 (90441295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOBAYASHI Hideyuki 小林 秀行

小林 秀行 コバヤシ ヒデユキ

Research Projects

Research Products

Co-Researchers

唾液によるホルモン測定に基づいた男性不妊AIリスク判定モデルの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

AI（人工知能）技術を活用した男性不妊症の新規診断法および治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

泌尿器癌の腫瘍免疫におけるVCANの役割の解明と免疫療法への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathology of varicocele and development of new treatments through analysis of sperm mitochondriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of male infertility by epigenome analysis of iPS cells derived from male infertility and stem cell researchPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The breakthrough of male infertily by stem cell researchPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and analysis of human spermatogonial stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Pluripotent Stem Cells2013

Author(s)

Publisher

Data Source

[Journal Article] Urine pH and imaging findings of prostate useful predictors of prolonged duration of hematospermia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combination of C-reactive protein/albumin ratio and time to castration resistance enhances prediction of prognosis for patients with metastatic castration-resistant prostate cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] AI Model Developed Using Machine Learning for Predicting Sperm Retrieval in Micro-TESE for Nonobstructive Azoospermia Patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular Mechanisms and Risk Factors Related to the Pathogenesis of Peyronie’s Disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Longitudinal change in castration-resistant prostate cancer biomarker AST/ALT ratio reflects tumor progression2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A method for utilizing automated machine learning for histopathological classification of testis based on Johnsen scores2021

Author(s)

Journal Title

DOI

KOBAYASHI Hideyuki 小林秀行

小林秀行コバヤシヒデユキ