Kariu Toru 狩生徹

… Alternative Names

KARIU Toru 狩生徹

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Researcher Number	10412735
Other IDs
Affiliation (Current)	2025: 別府大学, 食物栄養科学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 尚絅大学, 生活科学部, 教授 2019: 尚絅大学, 生活科学部, 教授 2013 – 2018: 尚絅大学, 生活科学部, 准教授 2009: 崇城大, 薬学部, 講師 2006 – 2008: 崇城大学, 薬学部, 講師 2007: 崇城大, 薬学部, 講師
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 38050:Food sciences-related / Eating habits / General surgery Except Principal Investigator Basic Section 57080:Social dentistry-related / Applied biochemistry
Keywords	Principal Investigator 歯周病 / 歯周病菌 / フラボノイド / 蛇毒 / ゴマリグナン / ゴマ / 食品 / プレニル化フラボノイド / エキソーム解析 / 乳がん … More / 血液凝固 / タンパク質 / 生化学 / 抗血液凝固 / ハブ … More Except Principal Investigator 外膜小胞 / アルツハイマー病 / ラマン分光法 / リキッドバイオプシー / 細胞外小胞 / セラミド / アミロイド線維 / ジンジパイン / transcription / venom / 毒素 / 発現調節 / ハブ / ハブ(ヘビ) / 転写 / 毒腺 Less

新規歯周病治療薬としてのゴマリグナン類の評価Principal Investigator
- Principal Investigator
  
  狩生徹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Shokei University
Development of next-generation liquid biopsy for Alzheimer's disease focusing on Porphyromonas gingivalis outer membrane vesicles
- Principal Investigator
  
  山本俊郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular fingerprint imaging to Alzheimer's disease development to produce by periodontal disease bacteria using raman spectroscopy
- Principal Investigator
  
  足立圭司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Kyoto Prefectural University of Medicine
プレニル化フラボノイドは、歯周病が引き起こす全身疾患を抑制できるか？Principal Investigator
- Principal Investigator
  
  狩生徹
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Research Field
  
  Eating habits
- Research Institution
  Shokei University
Identification and Analysis of Periodontitis Inhibitory Peptides from SesamePrincipal Investigator
- Principal Investigator
  
  Kariu Toru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Shokei University
Evaluation of the prenylated flavonoids as a novel anti-periodontitis agentPrincipal Investigator
- Principal Investigator
  
  Kariu Toru
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Shokei University
Analysis of novel mutations in triple negative breast cancer using NGSPrincipal Investigator
- Principal Investigator
  
  Kariu Toru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Shokei University
ハブ毒による血液凝固阻害・血管障害の分子病態解析Principal Investigator
- Principal Investigator
  
  狩生徹
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sojo University
Characterization of the novel anticoagulants from the venom of Protobothrops flavoviridisPrincipal Investigator
- Principal Investigator
  
  KARIU Toru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sojo University
アプタマーを用いた新規ハブ咬傷治療薬の開発Principal Investigator
- Principal Investigator
  
  狩生徹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sojo University
Molecular mechanisms in regulation of gene expression in Protobothrops flavoviridis venom gland.
- Principal Investigator
  
  ODA Naoko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Sojo University

All 2023 2019 2018 2017 2015 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] In Situ Raman Study of Neurodegenerated Human Neuroblastoma Cells Exposed to Outer-Membrane Vesicles Isolated from Porphyromonas gingivalis2023
- Author(s)
  Pezzotti Giuseppe、Adachi Tetsuya、Imamura Hayata、Bristol Davide Redolfi、Adachi Keiji、Yamamoto Toshiro、Kanamura Narisato、Marin Elia、Zhu Wenliang、Kawai Toshihisa、Mazda Osam、Kariu Toru、Waku Tomonori、Nichols Frank C.、Riello Pietro、Rizzolio Flavio、Limongi Tania、Okuma Kazu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 17 Pages: 13351-13351
- DOI
  10.3390/ijms241713351
- Data Source
  KAKENHI-PROJECT-22K10313, KAKENHI-PROJECT-23K09463
[Journal Article] BB0323 and novel virulence determinant BB0238: Borrelia burgdorferi proteins that interact with and stabilize each other and are critical for infectivity.2015
- Author(s)
  Kariu T, Sharma K, Singh P, Smith AA, Backstedt B, Buyuktanir O, Pal U
- Journal Title
  
  J Infect Dis.
  
  Volume: 211 Issue: 3 Pages: 462-71
- DOI
  10.1093/infdis/jiu460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461982
[Journal Article] Influence of the C5a-C5a receptor system on breast cancer progression and patient prognosis2015
- Author(s)
  Imamura, T. Yamamoto-Ibusuki, M. Sueta, A. Kubo, T. Irie, A. Kikuchi, K. Kariu, T. Iwase, H.
- Journal Title
  
  Breast Cancer
  
  Volume: Oct21 Issue: 6 Pages: 1-10
- DOI
  10.1007/s12282-015-0654-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460972, KAKENHI-PROJECT-25461982, KAKENHI-PROJECT-25460498, KAKENHI-PROJECT-16K08741
[Journal Article] Generation of drug-resistant mutants of Helicobacter pylori in the presence of peroxynitrite, a derivative of nitric oxide, at pathophysiological concentration2009
- Author(s)
  Kuwahara, H., Kariu, T., Fan, J. and Maeda, H
- Journal Title
  
  Microbiol. Immunol 53
  
  Pages: 1-7
- NAID
  10026403871
- Data Source
  KAKENHI-PROJECT-19790081
[Journal Article] Generation of drug-resistant mutants of Helicobacter pylozi in the presence of peroxynitrite, a derivative of nitricoxide, at pathophysiological concentration2009
- Author(s)
  Kuwahara H., Kariu T., Fan J. and Maeda H.
- Journal Title
  
  Microbiol. Immunol 53
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790081
[Presentation] 食に関する産学連携と地域貢献事例紹介2019
- Author(s)
  狩生徹
- Organizer
  くまもと産業復興支援プロジェクトフォーラム
- Data Source
  KAKENHI-PROJECT-16K00891
[Presentation] 食に関する産学連携と地域貢献事例紹介2018
- Author(s)
  狩生徹
- Organizer
  くまもと産業復興プロジェクトフォーラム2018
- Data Source
  KAKENHI-PROJECT-16K00891
[Presentation] 食に関する産学官コラボレーション事例の紹介2018
- Author(s)
  狩生徹
- Organizer
  FoodStyle2018
- Data Source
  KAKENHI-PROJECT-16K00891
[Presentation] プレニル化フラボノイドの歯周病菌増殖抑制活性2017
- Author(s)
  狩生徹
- Organizer
  くまもと産業復興支援プロジェクトフォーラム
- Place of Presentation
  熊本大学
- Year and Date
  2017-02-28
- Data Source
  KAKENHI-PROJECT-16K00891
[Presentation] ハブ毒中の新規な[Lys49]ホスホリパーゼA2の同定2008
- Author(s)
  村上達夫、狩生徹、高崎伸也、服部正策、千々岩崇仁、大野素徳、上田直子
- Organizer
  第54回毒素シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-09-05
- Data Source
  KAKENHI-PROJECT-19790081
[Presentation] 日本の南西諸島3島(奄美大島、徳之島、沖縄)のハブ(Protobothrops flavoviridis)毒成分の比較プロテオミクス2008
- Author(s)
  高崎伸也、村上達夫、狩生徹、千々岩崇仁、服部正策、大野素徳、上田直子
- Organizer
  BMB2008(日本分子生物学会年会・日本生化学会大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790081
[Presentation] 奄美大島ハブ毒特異的な新規な[Lys49]ホスホリパーゼA22007
- Author(s)
  村上達夫、狩生徹、高崎伸也、服部正策、千々岩崇仁、大野素徳、上田(小田)直子
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-04
- Data Source
  KAKENHI-PROJECT-19790081
[Presentation] 奄美大島特異的な新規な[Lys^<49>]ホスホリパーゼA_22007
- Author(s)
  村上達夫, 狩生徹, 高崎伸也, 服部正策, 千々岩崇仁, 大野素徳, 上田直子
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会年会合同年会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] ハブ(Protobothrops flavoviridis)毒腺中に含まれる新規出血因子の機能解析2007
- Author(s)
  狩生徹
- Organizer
  タンパク質の構造と機能に関する九州シンポジウム
- Place of Presentation
  大分
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-19790081
[Presentation] A novel [Lys^<49>]phospholipase A_2 specifically expressed in the venom of Amami-Oshima island Protobothrops flavovirids2007
- Author(s)
  Tatsuo Murakami, Tohru Kariu, Shinya Takazaki, Shosaku Hattori, Takahito Chjiwa, Motonori Ohno, Naoko Oda-Ueda
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会年会合同年会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] ハブ毒中の新規な[Lys^<49>]ホスホリパーゼA_2の同定2007
- Author(s)
  村上達夫, 狩生徹, 高崎伸也, 服部正策, 千々岩崇仁, 大野素徳, 上田直子
- Organizer
  第54回毒素シンポジウム
- Place of Presentation
  大阪府犬鳴グランドホテル
- Year and Date
  2007-09-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] ハブ毒中の新規な[Lys^<49>]ホスホリパーゼA2の同定2007
- Author(s)
  村上達夫, 狩生徹, 高崎伸也, 服部正策, 千々岩崇仁, 大野素徳, 上田直子
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  宮崎(宮崎県立図書館)
- Year and Date
  2007-05-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] 奄美大島ハブ特異的な新規[Lys49]ホスホリパーゼA22007
- Author(s)
  村上達夫、狩生徹、高崎伸也、服部正策、千々岩崇仁、大野素徳、上田(小田)直子
- Organizer
  BMB2007(日本分子生物学会年会・日本生化学会大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19790081
[Presentation] Naoko Oda-Ueda Novel[Lys^<49>] phospholipase A^2 sspeciffically expressed in the venom of Amami-Oshima island Protobothrops flavoviridis2007
- Author(s)
  Tatsuo Muramami, Tohru Kariu, Shinya Takazaki, Shosaku, Hattori, Takahito Chijiwa, Motnori Ohno
- Organizer
  The 30th Annual meeting Molecular Biology Society of Japan, The 80th Annual meeting of the Japanese Biochemial Society
- Place of Presentation
  Yokohama Japan
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] Motonori Ohno Naoko Oda-Ueda Identification of a novel[Lys^<49>] phospholipase A_2 from Amami-Oshima P. flavoviridis venom2007
- Author(s)
  Tatsuo Murakami, Tohru Kariu, Shinya Takazaki Shosaku Hattori, Takahito Chijiwa
- Organizer
  The 54th Annual Meeting of Japanese society for symposium on toxins
- Place of Presentation
  Osaka, Japan
- Year and Date
  2007-09-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] Error prone DNA polymerase κ from Protobothrops flavoviridis a member of the DinB family2006
- Author(s)
  Naoko Oda-Ueda, Tohru, Kariu, Akiko Fukuhara, Shinya Takazaki, Takahito Chijiwa, Motonori Ohno
- Organizer
  15th world congress on Animal, plant and Microbial Toxins
- Place of Presentation
  Glasgow,UK
- Year and Date
  2006-07-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] Motonori Ohno Error prone DNA polymerase k from Protobothrops flavovirichs a member of the DinB family.2006
- Author(s)
  Naoko Oda-Ueda, Tohru, Kariu, Akiko Fukuhara, Shinya Takazaki, Takahito Chijiwa
- Organizer
  15th world congress on Animal, plant Microbial Toxins Glasgow
- Place of Presentation
  UK
- Year and Date
  2006-07-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580098
[Presentation] Shosaku Hattori Venomics of Protobothrops flavoviridis venom gland phospholipase A^2.2006
- Author(s)
  Takahito Chijiwa, Naoki Ikeda, Tohru Kariu., Tomohisa Ogawa., Naoko Oda-Ueda
- Organizer
  15th world congress on Animal, plant and Glasgow
- Place of Presentation
  UK
- Year and Date
  2006-07-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580098

1. IMAMURA Takahisa (20176499)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 足立哲也 (10613573)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 山本俊郎 (40347472)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 金村成智 (70204542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. PEZZOTTI G. (70262962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ODA Naoko (70211828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAZAKI Shinya (90435149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 上田裕人 (60913564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 足立圭司 (70457951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 小原幸 (80275198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 和久友則 (30548699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 入江厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小田直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
14. PEZZOTTI Giuseppe

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kariu Toru 狩生 徹

KARIU Toru 狩生 徹

Research Projects

Research Products

Co-Researchers

新規歯周病治療薬としてのゴマリグナン類の評価Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of next-generation liquid biopsy for Alzheimer's disease focusing on Porphyromonas gingivalis outer membrane vesicles

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular fingerprint imaging to Alzheimer's disease development to produce by periodontal disease bacteria using raman spectroscopy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

プレニル化フラボノイドは、歯周病が引き起こす全身疾患を抑制できるか？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and Analysis of Periodontitis Inhibitory Peptides from SesamePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of the prenylated flavonoids as a novel anti-periodontitis agentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of novel mutations in triple negative breast cancer using NGSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ハブ毒による血液凝固阻害・血管障害の分子病態解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of the novel anticoagulants from the venom of Protobothrops flavoviridisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アプタマーを用いた新規ハブ咬傷治療薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms in regulation of gene expression in Protobothrops flavoviridis venom gland.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In Situ Raman Study of Neurodegenerated Human Neuroblastoma Cells Exposed to Outer-Membrane Vesicles Isolated from Porphyromonas gingivalis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BB0323 and novel virulence determinant BB0238: Borrelia burgdorferi proteins that interact with and stabilize each other and are critical for infectivity.2015

Author(s)

Journal Title

DOI

Kariu Toru 狩生徹

KARIU Toru 狩生徹