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Akahori Takahiro  赤堀 宇広

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AKAHORI Takahiro  赤堀 宇広

赤堀 宇広

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Researcher Number 10423922
Affiliation (Current) 2025: 奈良県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2018 – 2022: 奈良県立医科大学, 医学部, 学内講師
2017: 奈良県立医科大学, 医学部附属病院, 研究員
2016: 奈良県立医科大学, 医学部, 学内講師
2012 – 2013: 奈良県立医科大学, 医学部, 助教
2008: 医学部・付属病院, 研究員
Review Section/Research Field
Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / General surgery
Keywords
Principal Investigator
異所性脂肪 / 膵癌 / 運動介入 / 運動療法 / CD36 / 膵外分泌機能 / 外分泌機能 / 術前治療 / 異所性脂肪化 / HMGB-1 … More
Except Principal Investigator
… More 治療抵抗性 / 免疫治療 / 難治性消化器癌 / 消化器癌 / 腫瘍免疫 / 腫瘍内浸潤リンパ球 / 免疫療法 / 難治癌 / CD200 / 放射線治療 / 小分子化合物 / 膵癌 / T細胞 / CTLA-4 / PD-1 / 抗体療法 / 外科総論 Less
  • Research Projects

    (6 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (7 People)
  •  Development of Novel Pancreatic Cancer Exercise Intervention Therapy by CD36 Expression AnalysisPrincipal Investigator

    • Principal Investigator
      Akahori Takahiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nara Medical University
  •  Development of novel therapy with small molecule targeting CD200 against pancreatic cancer

    • Principal Investigator
      SHO MASAYUKI
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Nara Medical University
  •  Development of multimodal immunotherapeutic strategy for refractory gastrointestinal cancer

    • Principal Investigator
      SHO MASAYUKI
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nara Medical University
  •  Development of the new treatment strategy of the pancreatic cancer by clarifying the pathophysiology of the myosteatosis.Principal Investigator

    • Principal Investigator
      Akahori Takahiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nara Medical University
  •  Elucidation of the role of HMGB-1 in the pancreatic cancerPrincipal Investigator

    • Principal Investigator
      AKAHORI Takahiro
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Nara Medical University
  •  Targeting T cell negative pathway as a novel anticancer therapy

    • Principal Investigator
      MASAYUKI Sho
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nara Medical University

All 2021 2020 2018 2017 2008 2007

All Journal Article Presentation

  • [Journal Article] Clinical relevance of CD70 expression in resected pancreatic cancer: Prognostic value and therapeutic potential2021

    • Author(s)
      Nakamura Kota、Sho Masayuki、Akahori Takahiro、Nishiwada Satoshi、Kunishige Tomohiro、Nakagawa Kenji、Nagai Minako、Takagi Tadataka、Terai Taichi、Ikeda Naoya
    • Journal Title

      Pancreatology

      Volume: 21 Issue: 3 Pages: 573-580

    • DOI

      10.1016/j.pan.2021.01.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03734, KAKENHI-PROJECT-19K22668, KAKENHI-PROJECT-19K18130, KAKENHI-PROJECT-20K17660
  • [Journal Article] Transcriptomic Profiling Identifies an Exosomal microRNA Signature for Predicting Recurrence Following Surgery in Patients with Pancreatic Ductal Adenocarcinoma2021

    • Author(s)
      Nishiwada Satoshi、Cui Ya、Sho Masayuki、Jun Eunsung、Akahori Takahiro、Nakamura Kota、Sonohara Fuminori、Yamada Suguru、Fujii Tsutomu、Han In Woong、Tsai Susan、Kodera Yasuhiro、Park Joon Oh、Von Hoff Daniel、Kim Song Cheol、Li Wei、Goel Ajay
    • Journal Title

      Annals of Surgery

      Volume: Publish Ahead of Print Issue: 6 Pages: e876-e885

    • DOI

      10.1097/sla.0000000000004993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03734
  • [Journal Article] Does direct invasion of peripancreatic lymph nodes impact survival in patients with pancreatic ductal adenocarcinoma? A retrospective dual-center study2021

    • Author(s)
      Hashimoto Daisuke、Satoi Sohei、Ishida Mitsuaki、Nakagawa Kenji、Kotsuka Masaya、Takagi Tadataka、Ryota Hironori、Terai Taichi、Sakaguchi Tatsuma、Nagai Minako、Yamaki So、Akahori Takahiro、Yamamoto Tomohisa、Sekimoto Mitsugu、Sho Masayuki
    • Journal Title

      Pancreatology

      Volume: 21 Issue: 5 Pages: 884-891

    • DOI

      10.1016/j.pan.2021.03.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K17660, KAKENHI-PROJECT-19H03734
  • [Journal Article] Application of liquid biopsy for surgical management of pancreatic cancer2020

    • Author(s)
      Nagai Minako、Sho Masayuki、Akahori Takahiro、Nakagawa Kenji、Nakamura Kota
    • Journal Title

      Annals of Gastroenterological Surgery

      Volume: 4 Issue: 3 Pages: 216-223

    • DOI

      10.1002/ags3.12317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K22668
  • [Journal Article] A MicroRNA Signature Identifies Pancreatic Ductal Adenocarcinoma Patients at Risk for Lymph Node Metastases2020

    • Author(s)
      Nishiwada Satoshi、Sho Masayuki、Banwait Jasjit K.、Yamamura Kensuke、Akahori Takahiro、Nakamura Kota、Baba Hideo、Goel Ajay
    • Journal Title

      Gastroenterology

      Volume: 159 Issue: 2 Pages: 562-574

    • DOI

      10.1053/j.gastro.2020.04.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K22668
  • [Journal Article] 癌転移機構におけるT細胞Negative Pathwayの関与と新たな治療戦略2008

    • Author(s)
      庄雅之, 野見武男, 赤堀宇広, 中村信治, 山戸一郎, 中島祥介
    • Journal Title

      癌の臨床 54(3)

      Pages: 175-180

    • NAID

      110006330424

    • Data Source
      KAKENHI-PROJECT-19591491
  • [Journal Article] 消化器癌におけるT細胞negative pathwayの意義と新たな治療戦略2008

    • Author(s)
      庄雅之, 野見武男, 赤堀宇広, 中村信治, 山戸一郎, 中島祥介
    • Journal Title

      Biotherapy 22(2)

      Pages: 105-110

    • Data Source
      KAKENHI-PROJECT-19591491
  • [Journal Article] Significance and Therapeutic Potential of Programmed Death-1 Ligand/Programmed Death-1 Pathway in Human Pancreatic Cancer. 20072007

    • Author(s)
      Nomi T, Sho M, Akahori T, Hamada K, Kubo A, Kanehiro H, Nakamura S, Enomoto K, Yagita H, Azuma M, Nakajima Y. Clinical
    • Journal Title

      Clin Cancer Res 3(7)

      Pages: 2151-7

    • Data Source
      KAKENHI-PROJECT-19591491
  • [Presentation] 膵癌集学的治療非完遂予測におけるMuscle Attenuationの有用性2018

    • Author(s)
      赤堀 宇広
    • Organizer
      第49回 日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K10607
  • [Presentation] Impact of the preoperative muscle attenuation in patients with pancreatic cancer for the completion of the multimodal therapy2018

    • Author(s)
      赤堀 宇広
    • Organizer
      第30回 日本肝胆膵外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10607
  • [Presentation] Impact of preoperative sarcopenia in patients with pancreatic cancer2017

    • Author(s)
      Takahiro Akahori
    • Organizer
      第6回 アジア太平洋肝胆膵外科学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2017-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10607
  • [Presentation] 膵癌術前栄養障害スクリーニングにおけるMuscle Attenuationの有用性2017

    • Author(s)
      赤堀 宇広
    • Organizer
      第117回 日本外科学会定期学術集会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-16K10607
  • [Presentation] New insights into targeting T cell negative pathway in tumor immunity2008

    • Author(s)
      Masayuki Sho, Takeo Nomi, Takahiro Akahori, Ichiro Yamato, Hiromichi Kanehiro, Miyuki Azuma, Hisaya Akiba, Hideo Yagita, Yoshiyuki Nakajima
    • Organizer
      AACR 2008 annual meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2008-04-15
    • Data Source
      KAKENHI-PROJECT-19591491
  • [Presentation] Targeting T cell negative pathway induces powerful and long-lasting antitumor effect in vivo2007

    • Author(s)
      Masayuki Sho, Takeo Nomi, Takahiro Akahori, Hiromichi Kanehiro, Miyuki Azuma, Hideo Yagita, Yoshiyuki Nakajima
    • Organizer
      AACR 2007 annual meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2007-04-15
    • Data Source
      KAKENHI-PROJECT-19591491
  • [Presentation] Significance of T cell negative regulatory pathway in human gastrointestinal cancer2007

    • Author(s)
      Masayuki Sho, Takeo Nomi, Takahiro Akahori, Hiromichi Kanehiro, Miyuki Azuma, Hideo Yagita, Yoshiyuki Nakajima
    • Organizer
      第66回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19591491
  • 1.  MASAYUKI Sho (50364063)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  長井 美奈子 (80646092)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  高木 忠隆 (20833700)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  國安 弘基 (00253055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  中川 顕志 (30812341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  中村 広太 (30790802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  症 雅之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 10 results

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