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Matsui Takanori  松井 孝憲

… Alternative Names

MATSUI Takanori  松井 孝憲

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Researcher Number 10425233
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9506-7571
Affiliation (Current) 2025: 福井県立大学, 生物資源学部, 准教授
Affiliation (based on the past Project Information) *help 2023 – 2025: 福井県立大学, 生物資源学部, 准教授
2019 – 2022: 久留米大学, 医学部, 准教授
2012 – 2018: 久留米大学, 医学部, 講師
2015: 久留米大, 医学部, 講師
2010: Kurume University, 医学部, 助教
2008 – 2009: Kurume University, 医学部, 研究員
2007: Kurume University, 循環器病研究所, 研究員
Review Section/Research Field
Principal Investigator
Laboratory animal science / Basic Section 53040:Nephrology-related / Basic Section 42040:Laboratory animal science-related / Kidney internal medicine / Ophthalmology
Except Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 43030:Functional biochemistry-related / Functional biochemistry / Applied pharmacology / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords
Principal Investigator
アプタマー / 糖尿病腎症 / 動脈硬化症 / シグナル伝達 / 糖尿病 / 糖尿病性腎症 / 核酸医薬品 / 終末糖化産物 / 動脈硬化 / 修飾ペプチド … More / 疾患モデル / PEDFペプチド / PEDF / 機能性ペプチド / 動脈硬化症治療法 / PEDF受容体 / モデル動物 / 血管保護作用 / 分子生物学 / 糖尿病性網膜症 … More
Except Principal Investigator
RAGE / 翻訳後修飾 / RAGEアプタマー / 核酸医薬 / 敗血症 / 一酸化炭素 / ユビキチン / ヘムオキシゲナーゼ / AGE / 急性呼吸窮迫症候群 / NEC / 壊死性腸炎 / 急性腎障害 / タンパク質間相互作用 / 内因性一酸化炭素 / RNA sequence / HMGB-1 / 核移行シグナル / 酸化ストレス / アプタマー / 糖尿病合併症 / 癌治療 / 終末糖化産物受容体 / 終末糖化産物 / 核酸医薬品 / DNAアプタマー / 糖尿病合併症治療 / ユビキチン分解 / 血管合併症 / 腎症 / 血管障害 / AGE-アプタマー / AGEアプタマー / 糖尿病 Less
  • Research Projects

    (16 results)
  • Research Products

    (81 results)
  • Co-Researchers

    (23 People)
  •  敗血症性急性呼吸窮迫症候群に対する核酸医薬RAGEアプタマーによる革新的治療法の開発

    • Principal Investigator
      坂本 早季
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kurume University
  •  Aptamer Raised Against Receptor for Advanced Glycation End Products (RAGE) Improves Survival Rate in Septic Acute Kidney Injury Mice

    • Principal Investigator
      倉八 朋宏
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kurume University
  •  Development of an Innovative Therapy Utilizing RAGE Aptamer to Achieve Zero Mortality in Neonatal Necrotizing Enterocolitis.

    • Principal Investigator
      古賀 義法
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kurume University
  •  Development of a novel therapeutic approach for diabetic nephropathy by nucleic acid medicine (DNA aptamer).Principal Investigator

    • Principal Investigator
      松井 孝憲
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Fukui Prefectural University
  •  内因性一酸化炭素COの産生調節機構の解明と新規メディカルガスによる治療基盤の構築

    • Principal Investigator
      東元 祐一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Kurume University
  •  Identification of structures of advanced glycation end-products responsible for proatherosclerotic effects - analysis using aptamers.Principal Investigator

    • Principal Investigator
      Matsui Takanori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Kurume University
  •  Post-translational modifications regulating the activity and function of carbon monoxide synthase

    • Principal Investigator
      Higashimoto Yuichiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Kurume University
  •  Effects of DNA Aptamer Raised Against RAGE on Sepsis in Mice

    • Principal Investigator
      Koga Yoshinori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kurume University
  •  Development of novel treatment for diabetic nephropathy originate from functional modified peptides of pigment epitherium-derived factor.Principal Investigator

    • Principal Investigator
      Matsui Takanori
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kurume University
  •  Post-translational modifications regulating the activity and function of heme oxygenase

    • Principal Investigator
      Higashimoto Yuichiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kurume University
  •  Regulation of heme oxygenase activity by posttranslational modification

    • Principal Investigator
      HIGASHIMOTO Yuichiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kurume University
  •  Pigment epithelium-derived factor as a target for development of new animal model of arteriosclerosisPrincipal Investigator

    • Principal Investigator
      Matsui Takanori
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kurume University
  •  Development of DNA-aptamer raised against RAGE and its clinical application for cardiovascular disease and cancer

    • Principal Investigator
      Yamagishi Shoichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kurume University
  •  Therapeutic strategy for diabetic angiopathy using AGE aptamer

    • Principal Investigator
      YAMAGISHI Shoichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kurume University
  •  Protective role of PEDF in transgenic diabetic nephropathy mouse.Principal Investigator

    • Principal Investigator
      MATSUI Takanori
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kurume University
  •  Depressor effect of pigment epithelium-derived factor (PEDF) on vascular permeability.Principal Investigator

    • Principal Investigator
      MATSUI Takanori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kurume University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2010 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] Subcutaneous infusion of DNA aptamer raised against advanced glycation end products prevents loss of skeletal muscle mass and strength in aging-accelerated mice.2023

    • Author(s)
      Mori, Y., Ohara, M., Terasaki, M., Osaka, N., Yashima, H., Saito, T., Otoyama-Kataoka, Y., Omachi, T., Higashimoto, Y., Matsui, T., Fukui, T., Yamagishi, S.
    • Journal Title

      Biomedicines

      Volume: 11 Issue: 12 Pages: 3112-3125

    • DOI

      10.3390/biomedicines11123112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06136, KAKENHI-PROJECT-23K07732
  • [Journal Article] Computational Screening and Experimental Validation of Inhibitor Targeting the Complex Formation of Grb14 and Insulin Receptor2023

    • Author(s)
      Ochi Yosuke、Matsui Takanori、Inoue Keitaro、Monobe Kohei、Sakamoto Hiroshi、Aoki Shunsuke、Taira Junichi
    • Journal Title

      Molecules

      Volume: 29 Issue: 1 Pages: 198-198

    • DOI

      10.3390/molecules29010198

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K04964, KAKENHI-PROJECT-23K07732, KAKENHI-PUBLICLY-23H04427
  • [Journal Article] SMTP-44D inhibits atherosclerotic plaque formation in apolipoprotein-E null mice partly by suppressing the AGEs-RAGE axis.2023

    • Author(s)
      Terasaki, M., Shibata, K., Mori, Y., Saito, T., Matsui, T., Ohara, M., Fukui, T., Hasumi, K., Higashimoto, Y., Nobe, K., Yamagishi, S.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 24 Issue: 7 Pages: 6505-6518

    • DOI

      10.3390/ijms24076505

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06136, KAKENHI-PROJECT-22K08318, KAKENHI-PROJECT-20K06475, KAKENHI-PROJECT-20K07075, KAKENHI-PROJECT-23K07732
  • [Journal Article] The Expression of PEDF and its Putative Receptors in Hepatocellular Carcinoma and Background Liver Tissue2021

    • Author(s)
      AKIBA JUN、YOSHIDA TAKAFUMI、SADASHIMA EIJI、MURATA KAZUYA、MATSUI TAKANORI、YAMAGISHI SHO-ICHI、KUSANO HIRONORI、MIHARA YUTARO、MIZUOCHI SHINJI、KINJOU YOSHINAO、NAITO YOSHIKI、HISAKA TORU、SAKAI HISAMUNE、OKUDA KOJI、NAKASHIMA OSAMU、YANO HIROHISA
    • Journal Title

      Anticancer Research

      Volume: 41 Issue: 3 Pages: 1203-1212

    • DOI

      10.21873/anticanres.14877

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06461
  • [Journal Article] DNA aptamer raised against receptor for advanced glycation end products suppresses renal tubular damage and improves insulin resistance in diabetic mice2021

    • Author(s)
      Sotokawauchi Ami、Matsui Takanori、Higashimoto Yuichiro、Nishino Yuri、Koga Yoshinori、Yagi Minoru、Yamagishi Sho-ichi
    • Journal Title

      Diabetes and Vascular Disease Research

      Volume: 18 Issue: 1 Pages: 1-8

    • DOI

      10.1177/1479164121990533

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16387, KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574
  • [Journal Article] Pigment epithelium?derived factor inhibits advanced glycation end product?induced proliferation, VEGF and MMP?9 expression in breast cancer cells via interaction with laminin receptor2021

    • Author(s)
      Tsuruhisa Shiori、Matsui Takanori、Koga Yoshinori、Sotokawauchi Ami、Yagi Minoru、Yamagishi Sho-Ichi
    • Journal Title

      Oncology Letters

      Volume: 22 Issue: 2 Pages: 1-9

    • DOI

      10.3892/ol.2021.12890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574
  • [Journal Article] Glucose Variability is Independently Correlated with Serum Level of Pigment Epithelium-Derived Factor in Type 2 Diabetes2021

    • Author(s)
      Fujikawa Tomoki、Ohara Makoto、Kohata Yo、Nagaike Hiroe、Fukase Ayako、Osaka Naoya、Yashima Hironori、Sato Nobuko、Kushima Hideki、Shinmura Kyoko、Takahashi Yasuyoshi、Hiromura Munenori、Terasaki Michishige、Mori Yusaku、Fukui Tomoyasu、Matsui Takanori、Hirano Tsutomu、Yamagishi Sho-ichi
    • Journal Title

      Diabetes Therapy

      Volume: 12 Issue: 3 Pages: 827-842

    • DOI

      10.1007/s13300-021-01008-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06461
  • [Journal Article] DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice2021

    • Author(s)
      Koga Yoshinori、Sotokawauchi Ami、Higashimoto Yuichiro、Nishino Yuri、Hashizume Naoki、Kakuma Tatsuyuki、Akiba Jun、Tanaka Yoshiaki、Matsui Takanori、Yagi Minoru、Yamagishi Sho-ichi
    • Journal Title

      Oxidative Medicine and Cellular Longevity

      Volume: 2021 Issue: 1 Pages: 1-20

    • DOI

      10.1155/2021/9932311

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574, KAKENHI-PROJECT-19K09086
  • [Journal Article] Glucose-dependent insulinotropic polypeptide inhibits cardiac hypertrophy and fibrosis in diabetic mice via suppression of TGF-β22021

    • Author(s)
      Hiromura M, Mori Y, Terasaki M, Kushima H, Saito T, Osaka N, Yashima H, Ohara M, Fukui T, Matsui T, Yamagishi SI.
    • Journal Title

      Diab Vasc Dis Res

      Volume: 18 Issue: 2 Pages: 1-8

    • DOI

      10.1177/1479164121999034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06574
  • [Journal Article] Association of advanced glycation end products with sarcopenia and frailty in chronic kidney disease.2020

    • Author(s)
      Yabuuchi、J., Ueda, S., Yamagishi, S-I, Nohara, N., Nagasawa, H., Wakabayashi, K., Matsui, T., Higashimoto Y., Kadoguchi, T., Otsuka, T., Gohda, T., Suzuki, Y.
    • Journal Title

      Sci. Rep.

      Volume: 10 Issue: 1 Pages: 17647-17659

    • DOI

      10.1038/s41598-020-74673-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06574, KAKENHI-PROJECT-19K17718, KAKENHI-PROJECT-18K08251, KAKENHI-PROJECT-18K17935
  • [Journal Article] Glyceraldehyde-Derived Pyridinium Evokes Renal Tubular Cell Damage via RAGE Interaction.2020

    • Author(s)
      Ami Sotokawauchi, Nobutaka Nakamura, Takanori Matsui, Yuichiro Higashimoto, Sho-ichi Yamagishi
    • Journal Title

      Int J Mol Sci.

      Volume: 21 Issue: 7 Pages: 2604-2611

    • DOI

      10.3390/ijms21072604

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-19K06574
  • [Journal Article] Fibroblast growth factor 23 contributes to regulation of hepcidin/ferroportin axis.2020

    • Author(s)
      Higashimoto, Y., Tanaka, K., Matsui, T., Sakaguchi, T., Yamagishi, S.I., Motomiya, Y.
    • Journal Title

      Austin J. Pharmacol. Ther.

      Volume: 8 Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06574
  • [Journal Article] Pathological role of advanced glycation end products (AGEs) and their receptor axis in atrial fibrillation2019

    • Author(s)
      Yamagishi Sho-ichi、Sotokawauchi Ami、Matsui Takanori
    • Journal Title

      Mini-Reviews in Medicinal Chemistry

      Volume: 19 Issue: 13 Pages: 1040-1048

    • DOI

      10.2174/1389557519666190311140737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101
  • [Journal Article] Switching dipeptidyl peptidase-4 inhibitors to tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2 improves arterial stiffness evaluated by cardio-ankle vascular index in patients with type 2 diabetes2019

    • Author(s)
      Tahara Nobuhiro、Yamagish Sho-ichi、Bekki Munehisa、Tahara Atsuko、Igata Sachiyo、Honda Akihiro、Sugiyama Yoichi、Nakamura Tomohisa、Sun Jiahui、Kumashiro Yuki、Matsui Takanori、Fukumoto Yoshihiro
    • Journal Title

      Current Vascular Pharmacology

      Volume: 17 Issue: 4 Pages: 411-420

    • DOI

      10.2174/1570161116666180515154555

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07101, KAKENHI-PROJECT-17K09564
  • [Journal Article] Fructose causes endothelial cell damage via activation of advanced glycation end products-receptor system.2019

    • Author(s)
      Sotokawauchi A, Matsui T, Higashimoto Y, Yamagishi SI.
    • Journal Title

      Diab. Vasc. Dis. Res.

      Volume: 16 Issue: 6 Pages: 556-561

    • DOI

      10.1177/1479164119866390

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06574, KAKENHI-PROJECT-17K08968
  • [Journal Article] Serum Levels of Protein-Bound Methylglyoxal-Derived Hydroimidazolone-1 are Independently Correlated with Asymmetric Dimethylarginine2019

    • Author(s)
      Tahara Nobuhiro、Kojima Ruchia、Yoshida Risa、Bekki Munehisa、Sugiyama Yoichi、Tahara Atsuko、Maeda Shoko、Honda Akihiro、Igata Sachiyo、Nakamura Tomohisa、Sun Jiahui、Matsui Takanori、Fukumoto Yoshihiro、Matsui Toshiro、Yamagishi Sho-Ichi
    • Journal Title

      Rejuvenation Research

      Volume: 印刷中 Issue: 5 Pages: 431-438

    • DOI

      10.1089/rej.2018.2152

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101, KAKENHI-PROJECT-17K09564
  • [Journal Article] Long-Term Local Injection of RAGE-Aptamer Suppresses the Growth of Malignant Melanoma in Nude Mice.2019

    • Author(s)
      Nakamura N, Matsui T, Nishino Y, Sotokawauchi A, Higashimoto Y, Yamagishi SI.
    • Journal Title

      J. Oncol.

      Volume: 2019 Pages: 387601-10

    • DOI

      10.1155/2019/7387601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06574
  • [Journal Article] Role of Ligands of Receptor for Advanced Glycation End Products (RAGE) in Peripheral Artery Disease2018

    • Author(s)
      Yamagishi Sho-ichi、Matsui Takanori
    • Journal Title

      Rejuvenation Research

      Volume: 21 Issue: 5 Pages: 456-463

    • DOI

      10.1089/rej.2017.2025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101
  • [Journal Article] Role of Hyperglycemia-Induced Advanced Glycation End Product (AGE) Accumulation in Atherosclerosis2018

    • Author(s)
      Yamagishi Sho-ichi、Matsui Takanori
    • Journal Title

      Ann Vasc Dis

      Volume: 11 Issue: 3 Pages: 253-258

    • DOI

      10.3400/avd.ra.18-00070

    • NAID

      130007487741

    • ISSN
      1881-641X, 1881-6428
    • Year and Date
      2018-09-25
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101
  • [Journal Article] Advanced glycation end products evoke inflammatory reactions in proximal tubular cells via autocrine production of dipeptidyl peptidase-42018

    • Author(s)
      Kaifu Kumiko、Ueda Seiji、Nakamura Nobutaka、Matsui Takanori、Yamada-Obara Nana、Ando Ryotaro、Kaida Yusuke、Nakata Masami、Matsukuma-Toyonaga Maki、Higashimoto Yuichiro、Fukami Kei、Suzuki Yusuke、Okuda Seiya、Yamagishi Sho-ichi
    • Journal Title

      Microvascular Research

      Volume: 120 Pages: 90-93

    • DOI

      10.1016/j.mvr.2018.07.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-18K08251, KAKENHI-PROJECT-16K07101, KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K09637
  • [Journal Article] N-butanol extracts of noni suppress advanced glycation end products (AGEs)-induced inflammatory and thrombotic reactions in endothelial cells through its anti-oxidative properties2017

    • Author(s)
      Ishibashi, Y., Matsui, T., Abe, Y., Sakaguchi, T., Higashimoto, Y., Yamagishi, S.
    • Journal Title

      BMC Complementary and Alternative Medicine

      Volume: 17(1) Issue: 1 Pages: 137-137

    • DOI

      10.1186/s12906-017-1641-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07018, KAKENHI-PROJECT-16K07307
  • [Journal Article] Glycation and cardiovascular disease in diabetes: A perspective on the concept of metabolic memory.2017

    • Author(s)
      Yamagishi SI, Nakamura N, Matsui T.
    • Journal Title

      J Diabetes.

      Volume: 9 Issue: 2 Pages: 141-148

    • DOI

      10.1111/1753-0407.12475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Journal Article] RAGE-aptamer Blocks the Development and Progression of Experimental Diabetic Nephropathy.2017

    • Author(s)
      Matsui, T., Higashimoto, Y., Nishino, Y., Nakamura, N., Fukami, K., Yamagishi, S.
    • Journal Title

      Diabetes

      Volume: 66 Issue: 1 Pages: 1683-1695

    • DOI

      10.1038/s41598-018-21176-5

    • NAID

      40021434304

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K08564, KAKENHI-PROJECT-16K19502, KAKENHI-PROJECT-16K09637, KAKENHI-PROJECT-18H02823, KAKENHI-PROJECT-17K19653
  • [Journal Article] RAGE-aptamer inhibits the growth and liver metastasis of melanoma in nude mice.2017

    • Author(s)
      Nakamura, N., Matsui, T., Ishibashi, Y., Sotokawauchi, A., Fukami, K., Higashimoto, Y., Yamagishi, S.
    • Journal Title

      Mol. Med.

      Volume: 23 Issue: 1 Pages: 295-306

    • DOI

      10.2119/molmed.2017.00099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K09637
  • [Journal Article] Phytochemicals against advanced glycation end products (AGEs) and the receptor system2017

    • Author(s)
      Yamagishi, S., Matsui, T., Ishibashi, Y., Abe, Y., Sakaguchi, T., Higashimoto, Y.
    • Journal Title

      Current Pharmaceutical Design

      Volume: 23(8) Issue: 8 Pages: 1135-1141

    • DOI

      10.2174/1381612822666161021155502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07018, KAKENHI-PROJECT-16K07307
  • [Journal Article] Methylglyoxal-derived hydroimidazolone-1 evokes inflammatory reactions in endothelial cells via an interaction with RAGE.2017

    • Author(s)
      Ishibashi, Y., Matsui, T., Nakamura, N., Sotokawauchi, A., Higashimoto, Y., Yamagishi, S.
    • Journal Title

      Diabetes Vasc. Dis. Res.

      Volume: 14 Issue: 5 Pages: 450-453

    • DOI

      10.1177/1479164117715855

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Journal Article] Sulforaphane reduces advanced glycation end products (AGEs)-induced inflammation in endothelial cells and rat aorta.2016

    • Author(s)
      Matsui T, Nakamura N, Ojima A, Nishino Y, Yamagishi SI.
    • Journal Title

      Nutr Metab Cardiovasc Dis.

      Volume: 26 Issue: 9 Pages: 797-807

    • DOI

      10.1016/j.numecd.2016.04.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Journal Article] Protective role of sulphoraphane against vascular complications in diabetes.2016

    • Author(s)
      Yamagishi S, Matsui T.
    • Journal Title

      Pharm Biol.

      Volume: 54 Issue: 10 Pages: 2329-2339

    • DOI

      10.3109/13880209.2016.1138314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Journal Article] Serum Levels of Growth Differentiation Factor 11 Are Independently Associated with Low Hemoglobin Values in Hemodialysis Patients.2016

    • Author(s)
      Yamagishi S, Matsui T, Kurokawa Y, Fukami K.
    • Journal Title

      Biores Open Access.

      Volume: 5 Issue: 1 Pages: 155-158

    • DOI

      10.1089/biores.2016.0015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Journal Article] Protective Role of PEDF-Derived Synthetic Peptide against Experimental Diabetic Nephropathy.2016

    • Author(s)
      Ishibashi, Y., Matsui, T., Taira, J., Higashimoto, Y., Yamagishi, S.
    • Journal Title

      Hormone and Metabolic Research

      Volume: 48(09) Issue: 09 Pages: 613-619

    • DOI

      10.1055/s-0042-108448

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07018, KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K21226
  • [Journal Article] DNA Aptamer Raised Against Advanced Glycation End Products (AGEs) Improves Glycemic Control and Decreases Adipocyte Size in Fructose-Fed Rats by Suppressing AGE-RAGE Axis2015

    • Author(s)
      Ojima, A., Matsui, T., Nakamura, N., Higashimoto, Y., Ueda, S., Fukami, K., Okuda, S., Yamagishi, S.I.
    • Journal Title

      Hormone and Metabolic Research

      Volume: 47(4) Issue: 04 Pages: 253-258

    • DOI

      10.1055/s-0034-1385904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-15K07018
  • [Journal Article] DNA aptamer raised against advanced glycation end products (AGEs) prevents abnormalities in electroretinogram of experimental diabetic retinopathy.2015

    • Author(s)
      Maeda, S., Matsui, T., Ojima, A., Suematsu, M., Kaseda, K., Higashimoto, Y., Yamakawa, R., Yamagishi, S.
    • Journal Title

      Ophthalmic Res.

      Volume: 54 Issue: 4 Pages: 175-180

    • DOI

      10.1159/000440768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-15K07018
  • [Journal Article] Development of a monoclonal antibody-based ELISA system for glyceraldehyde-derived advanced glycation end products.2015

    • Author(s)
      Matsui, T., Joo, H.D., Lee, J.M., Ju, S.M., Tao, W.H., Higashimoto, Y., Fukami, K., Yamagishi, S.I.
    • Journal Title

      Immunol. lett.

      Volume: 161 Issue: 2 Pages: 141-146

    • DOI

      10.1016/j.imlet.2015.08.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-15K07018
  • [Journal Article] Pigment epithelium-derived factor inhibits caveolin-induced interleukin‑8 gene expression and proliferation of human prostate cancer cells.2015

    • Author(s)
      Matsui, T., Ojima, A., Higashimoto, Y., Taira, J., Fukami, K., Yamagishi, S.
    • Journal Title

      Oncol. Lett.

      Volume: 10 Issue: 4 Pages: 2644-2648

    • DOI

      10.3892/ol.2015.3568

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-15K07018
  • [Journal Article] DNA aptamer raised against advanced glycation end products inhibits neointimal hyperplasia in balloon-injured rat carotid arteries2014

    • Author(s)
      Ayako Ojima, Eriko Oda, Yuichiro Higashimoto, Takanori Matsui, Sho-ichi Yamagishi
    • Journal Title

      International Journal of Cardiology

      Volume: 171(3) Issue: 3 Pages: 443-446

    • DOI

      10.1016/j.ijcard.2013.12.143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25440056
  • [Journal Article] DNA aptamer raised against advanced glycation end products inhibits melanoma growth in nude mice2014

    • Author(s)
      Ayako Ojima, Takanori Matsui, Sayaka Maeda, Masayoshi Takeuchi, Hiroyoshi Inoue, Yuichiro Higashimoto, Sho-ichi Yamagishi
    • Journal Title

      Laboratory Investigation

      Volume: 94(4) Issue: 4 Pages: 422-429

    • DOI

      10.1038/labinvest.2014.5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056
  • [Journal Article] Laminin receptor mediates anti-inflammatory and anti-thrombogenic effects of pigment epithelium-derived factor in myeloma cells.2014

    • Author(s)
      Matsui, T., Higashimoto, Y., and Yamagishi, S.I.
    • Journal Title

      Biochem. Biophys. Res. Commn.

      Volume: 443 Issue: 3 Pages: 847-851

    • DOI

      10.1016/j.bbrc.2013.12.060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25440056
  • [Journal Article] Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor2013

    • Author(s)
      Ishibashi Y, Matsui T, Maeda S, Higashimoto Y., Yamagishi S.I.
    • Journal Title

      Cardiovasc. Diabetol.

      Volume: 12 Issue: 1 Pages: 125-134

    • DOI

      10.1186/1475-2840-12-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25440056
  • [Journal Article] Pigment epithelium-derived factor (PEDF) binds to caveolin-1 and inhibits the pro-inflammatory effects of caveolin-1 in endothelial cells2013

    • Author(s)
      Matsui, T., Higashimoto, Y., Taira, J., Yamagishi, S.I.
    • Journal Title

      Biochem. Biophys. Res. Commn.

      Volume: 441 Issue: 2 Pages: 405-410

    • DOI

      10.1016/j.bbrc.2013.10.074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25440056
  • [Journal Article] Blockade by phosphorothioate aptamers of advanced glycation end products-induced damage in cultured pericytes and endothelial cells2013

    • Author(s)
      Higashimoto, Y., Matsui, T., Nishino, Y., Taira, J., Inoue, H., Takeuchi, M., Yamagishi, S.I.
    • Journal Title

      Microvasc. Res.

      Volume: 90 Pages: 64-70

    • DOI

      10.1016/j.mvr.2013.08.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-25870990
  • [Journal Article] DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy.2013

    • Author(s)
      Kaida Y,Fukami K, Matsui T,HigashimotoY,NishinoY,ObaraN,Nakayama Y, Ando R, Toyonaga M, Ueda S,TakeuchiM,InoueH,OkudaS,Yamagishi SI
    • Journal Title

      Diabetes

      Volume: 62 Issue: 9 Pages: 3241-3250

    • DOI

      10.2337/db12-1608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390111, KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056
  • [Journal Article] Pigment epithelium-derived factor inhibits advanced glycation end product-elicited mesangial cell damage by blocking NF-kappaB activation.2010

    • Author(s)
      松井孝憲、山岸昌一
    • Journal Title

      Microvascular research

      Volume: 80巻 Pages: 227-232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790824
  • [Journal Article] Administration of pigment epithelium-derived factor prolongs bleeding time by suppressing plasminogen activator inhibitor-1 activity and platelet aggregation in rats2009

    • Author(s)
      Yamagishi S, Matsui T, Nakamura K, Takenaka K.
    • Journal Title

      Clinical and Experimental Medicine 9

      Pages: 731-736

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791303
  • [Presentation] SMTP-44DはApoE 欠損マウスの動脈硬化進展を抑制する2023

    • Author(s)
      寺崎道重、柴田佳太, 森雄作、斎藤智美、松井孝憲、八島広典、大坂直也、藤川大輝、高畑洋、広村宗範、竹鼻伸晃、高橋範之、江波戸彩乃、小原信、福井智康、蓮見惠司、東元祐一郎、野部浩司、山岸昌一
    • Organizer
      第23回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] AGE-RAGE系阻害アプタマーは、マウスにおいて悪性メラノーマの増殖と転移を抑制する2023

    • Author(s)
      松井孝憲、東元祐一郎、外川内亜美、山岸昌一
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] 線維芽細胞増殖因子23(FGF23)のヘプシジン/フェロポーチンシステムによる鉄代謝への関与2023

    • Author(s)
      東元祐一郎、松井孝憲、坂口達也、田中祐有、本宮善恢
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] 終末糖化産物受容体を阻害するRAGE アプタマーは敗血症マウスの生存率を改善する2023

    • Author(s)
      古賀義法、松井孝憲、外川内亜美、東元祐一郎、角間辰之、秋葉純、八木実、山岸昌一
    • Organizer
      第23回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] Fibroblast growth factor 23 (FGF23) contributes to regulation of hepcidin/ferroportin axis2023

    • Author(s)
      東元祐一郎、松井孝憲、坂口達也、田中祐有、本宮善恢
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] 終末糖化産物(AGEs)の阻害による老年病の包括的抑制2022

    • Author(s)
      松井孝憲、東元祐一郎、山岸昌一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] DNAアプタマーによる終末糖化産物受容体の阻害は老年疾患を包括的に抑制する2022

    • Author(s)
      外川内亜美、東元祐一郎、古賀義法、西野友梨、松井孝憲、山岸昌一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] DNAアプタマーを用いた終末糖化産物受容体(RAGE)の阻害によるマウス敗血症の治療法の開発2022

    • Author(s)
      古賀義法、松井孝憲、外川内亜美、東元祐一郎、角間辰之、秋葉純、八木実、山岸昌一
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06136
  • [Presentation] 終末糖化産物受容体RAGEを阻害するDNAアプタマーは,2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021

    • Author(s)
      外川内亜美、松井孝憲、西野友梨、東元祐一郎、山岸昌一
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K06461
  • [Presentation] 新規敗血症治療薬の開発:終末糖化産物受容体阻害薬は敗血症モデルマウスの 生存率を改善させる2021

    • Author(s)
      古賀 義法,外川内 亜美,西野 友梨,松井 孝憲,角間 辰之,秋葉 純,東元 祐一郎,八木 実,山岸 昌一
    • Organizer
      第121回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19K09086
  • [Presentation] DNAアプタマーによるAGE-RAGE系の阻害は老年疾患を包括的に抑制する2021

    • Author(s)
      外川内 亜美、東元 祐一郎、古賀 義法、松井 孝憲、山岸 昌一
    • Organizer
      8)第32回脳心血管抗加齢研究会第17回学術大会・日本抗加齢協会第5回学術フォーラム
    • Data Source
      KAKENHI-PROJECT-19K06461
  • [Presentation] 内皮細胞におけるグリセルアルデヒド由来AGEsのRAGEを介した炎症作用は DNAアプタマーにより抑制しうる2021

    • Author(s)
      松井孝憲、外川内亜美、東元祐一郎、山岸昌一
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K06461
  • [Presentation] 新規敗血症治療薬の開発:終末糖化産物受容体阻害薬の敗血症への臨床応用を目指して2021

    • Author(s)
      古賀 義法,外川内 亜美,西野,友梨,松井 孝憲,角間 辰之,秋葉 純,東元 祐一郎,八木 実,山岸 昌一
    • Organizer
      第48回日本集中治療医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09086
  • [Presentation] 敗血症における終末糖化産物受容体阻害薬の臨床応用2020

    • Author(s)
      古賀 義法、松井 孝憲、田中 芳明、八木 実、山岸 昌一
    • Organizer
      第57回 日本小児外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09086
  • [Presentation] 終末糖化産物(AGE)及びその受容体(RAGE)をターゲットとしたDNAアプタマーは動物モデルの悪性黒色腫の増殖を抑制する2019

    • Author(s)
      松井孝憲、東元祐一郎、外川内亜美、山岸昌一
    • Organizer
      第5回日本核酸医薬学会年会
    • Data Source
      KAKENHI-PROJECT-19K06574
  • [Presentation] 終末糖化産物受容体阻害アプタマーの敗血症への臨床応用2019

    • Author(s)
      古賀 義法、松井 孝憲、田中 芳明、八木 実、山岸 昌一
    • Organizer
      日本外科代謝栄養学会第56回学術集会
    • Data Source
      KAKENHI-PROJECT-19K09086
  • [Presentation] APTAMER RAISED AGAINST RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (RAGE) IMPROVES SURVIVAL RATE IN SEPTIC MICE2019

    • Author(s)
      古賀義法、外川内亜美、東元祐一郎、松井孝憲、八木実、山岸昌一
    • Organizer
      32nd International Symposium on Pediatric Surgical Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06574
  • [Presentation] Aptamer Raised Against Receptor for Advanced Glycation End Products (RAGE) Improves Survival Rate in Septic Mice2019

    • Author(s)
      Yoshinori Koga , Ami Sotokawauchi , Yuichiro Higashimoto, Takanori Matsui , Minoru Yagi, Sho-ichi Yamagishi
    • Organizer
      (International Symposium on Pediatric Surgical Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09086
  • [Presentation] マウス皮下に移植した悪性黒色腫の増殖は終末糖化産物(AGE)及びその受容体(RAGE)のDNAアプタマーにより抑制しうる2019

    • Author(s)
      松井孝憲、東元祐一郎、外川内亜美、山岸昌一
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06574
  • [Presentation] フルクトース由来終末糖化産物のアプタマーはフルクトースが引き起こす内皮細胞障害を抑制しうる2019

    • Author(s)
      外川内亜美、松井孝憲、東元祐一郎、山岸昌一
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06574
  • [Presentation] 終末糖化産物受容体(RAGE)のアプタマーは動物の糖尿病腎症の発症・増悪と悪性黒色腫の増殖・転移を阻害する2018

    • Author(s)
      松井孝憲,中村信孝, 東元祐一郎, 山岸昌一
    • Organizer
      第41回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16K07101
  • [Presentation] 終末糖化産物受容体(RAGE)アプタマーは動物モデルの糖尿病性腎症の発症・憎悪、悪性黒色腫の増殖・転移を抑制する2018

    • Author(s)
      松井孝憲、東元祐一郎、中村信孝、山岸昌一
    • Organizer
      第4回日本核酸医薬学会年会
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Presentation] トホグリフロジンは尿細管保護効果により2型糖尿病マウスの腎障害を改善する2018

    • Author(s)
      松井 孝憲、石橋裕二、山岸 昌一
    • Organizer
      第61回日本糖尿病学会
    • Data Source
      KAKENHI-PROJECT-16K07101
  • [Presentation] 終末糖化産物受容体(RAGE)アプタマーはラットの糖尿病腎症の発症と進展を抑制する2018

    • Author(s)
      松井孝憲, 山岸昌一
    • Organizer
      第61回日本腎臓学会
    • Data Source
      KAKENHI-PROJECT-16K07101
  • [Presentation] 終末糖化産物受容体(RAGE)アプタマーは動物モデルの糖尿病腎症の発症・増悪,悪性黒色腫の増殖・転移を抑制する2018

    • Author(s)
      松井孝憲, 中村信孝, 東元祐一郎, 山岸昌一
    • Organizer
      日本核酸医薬学会第4回年会
    • Data Source
      KAKENHI-PROJECT-16K07101
  • [Presentation] 終末糖化産物受容体(RAGE)アプタマーは動物の糖尿病腎症の発症・増悪と悪性黒色腫の増殖・転移を阻害する2018

    • Author(s)
      松井孝憲、中村信孝、東元祐一郎、山岸昌一
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Presentation] RAGE-DNA APTAMER IMPROVES MR-ASSOCIATED RENAL INJURY THROUGH RAC1-MEDIATED MR ACTIVATION2016

    • Author(s)
      田口顕正、山岸昌一、松井孝憲、東元祐一郎、淺沼克彦、上田誠二、深水圭
    • Organizer
      第53回欧州腎臓学会・欧州透析移植学会
    • Place of Presentation
      Austria Center Vienna (オーストリア・ウィーン)
    • Year and Date
      2016-05-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Presentation] RAGE-DNA aptamerはAGEs-RAGE系を抑制しMR活性腎障害を改善する2016

    • Author(s)
      田口顕正、山岸昌一、松井孝憲、東元祐一郎、淺沼克彦、上田誠二、深水圭
    • Organizer
      第59回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Presentation] AGEアプタマーはバルーンにより損傷したラット頚動脈中における新生血管内膜の過形成を抑制する2016

    • Author(s)
      東元祐一郎、尾嶋亜弥子、小田えり子、松井孝憲、山岸昌一
    • Organizer
      第2回日本核酸医薬学会年会
    • Place of Presentation
      東京理科大学(東京都葛飾区)
    • Year and Date
      2016-11-16
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Presentation] 終末糖化産物受容体(RAGE)のDNAアプタマーはラットの糖尿病腎症を改善する2016

    • Author(s)
      松井孝憲、東元祐一郎、山岸昌一
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-26
    • Data Source
      KAKENHI-PROJECT-16K07307
  • [Presentation] AGEアプタマーのバルーン障害後血管リモデリングに対する効果2016

    • Author(s)
      東元祐一郎、尾嶋 亜弥子、小田えり子、松井孝憲、山岸昌一
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-10
    • Data Source
      KAKENHI-PROJECT-25440056
  • [Presentation] グリセルアルデヒド由来ピリジニウム(GLAP)はHUVECにおいてRAGEを介した酸化ストレスと炎症性反応と血栓性反応の増悪を引き起こす2015

    • Author(s)
      松井孝憲、東元祐一郎、小田えり子、山岸昌一
    • Organizer
      第88回日本生化学会大会(BMB2015)
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25440056
  • [Presentation] AGEアプタマーはバルーンにより損傷したラット頚動脈中における新生血管内膜の過形成を抑制する2015

    • Author(s)
      東元祐一郎、尾嶋亜弥子、小田えり子、松井孝憲、山岸昌一
    • Organizer
      第88回日本生化学会大会(BMB2015)
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25440056
  • [Presentation] 終末糖化産物(AGEs)特異的DNAアプタマーはヌードマウスにおけるメラノーマ増殖を抑制する2014

    • Author(s)
      東元祐一郎、松井孝憲、尾嶋亜弥子、前田沙耶香、竹内正義、井上浩義、山岸昌一
    • Organizer
      第87回 日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市左京区)
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-25440056
  • [Presentation] AGEs特異的DNAアプタマーによる糖尿病性腎症の進展抑制効果2014

    • Author(s)
      東元祐一郎、甲斐田裕介、松井孝憲、深水圭、奥田誠也、山岸昌一、竹内正義、井上浩義
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-25440056
  • [Presentation] PEDFは内皮細胞のカベオリン-1による炎症誘発作用を阻害する2014

    • Author(s)
      松井孝憲、東元祐一郎、平順一、山岸昌一
    • Organizer
      第87回 日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市左京区)
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-25440056
  • [Presentation] PEDF(色素上皮由来因子)はAGEs由来の酸化ストレスの産生を抑制し、初期糖尿病網膜症の発症を阻止する2008

    • Author(s)
      松井孝憲、山岸昌一、中村和生、竹内正義、今泉勉
    • Organizer
      日本糖尿病学会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19791303
  • [Presentation] PEDFは終末糖化産物(AGEs)由来の酸化ストレスの産生を抑制し、網膜微小血管への白血球の接着促進と血管透過性の亢進とを抑え、初期糖尿病網膜症の発症を阻止する。2007

    • Author(s)
      松井 孝憲
    • Organizer
      第15回 日本血管生物医学会学術大会
    • Place of Presentation
      九州大学医学部 百年講堂
    • Year and Date
      2007-11-30
    • Data Source
      KAKENHI-PROJECT-19791303
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