ISHIBASHI Daisuke 石橋大輔

… Alternative Names

ISHIBASHI Ishibashi 石橋大輔

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Researcher Number	10432973
Other IDs
External Links
Affiliation (Current)	2025: 福岡大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 福岡大学, 薬学部, 教授 2021: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2016 – 2019: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2014: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2012 – 2013: 長崎大学, 医歯(薬)学総合研究科, 助教 … More 2011: 長崎大学, 大学院・医歯薬学総合研究科, 助教 2010: 長崎大学, 医歯(薬)学総合研究科, 助教 2007 – 2008: Nagasaki University, 大学院・医歯薬学総合研究科, 助教 Less
Review Section/Research Field	Principal Investigator Infectious disease medicine / Basic Section 52020:Neurology-related / Medium-sized Section 52:General internal medicine and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Nerve anatomy/Neuropathology / Neurology Except Principal Investigator Basic Section 62010:Life, health and medical informatics-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator プリオン / 自然免疫 / インターフェロン / IRF3 / 脳神経疾患 / 核酸医薬 / 難治性疾患 / Interferon / Innate immunity / Prion … More / I型インターフェロン受容体 / ISGs / Oct-1 / IFN / innate immunity / prion / 感染症 / 神経病態生化学 … More Except Principal Investigator プリオン病 / 有機合成 / ファーマコフォアモデル / 分子動力学計算 / 化学シャペロン / 構造解析 / ドッキング計算 / 神経疾患 / プリオン / アミロイド / 液相分離 Less

Development of an effective pharmacophore model for chemical chaperones and its application to anti-prion drugs
- Principal Investigator
  
  石川岳志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Kagoshima University
難治性疾患を対象とした臓器指向性をもつ次世代核酸医薬の開発Principal Investigator
- Principal Investigator
  
  石橋大輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Fukuoka University
病原体プリオンに対する生体防御機構の解明および免疫システムに着目した治療薬の開発Principal Investigator
- Principal Investigator
  
  石橋大輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Fukuoka University
Construction of the pharmacophore model of antiprion compounds for development of a novel therapeutic agent
- Principal Investigator
  
  Ishikawa Takeshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Kagoshima University
Investigation of pathological mechanism, and innate immune targeting drug discovery in prion diseasPrincipal Investigator
- Principal Investigator
  
  Ishibashi Daisuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Fukuoka University
  Nagasaki University
Replication of sCJD in vtro
- Principal Investigator
  
  Nishida Noriyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagasaki University
The elucidation of molecular pathological condition in prion disease: analysis of interferon system to develop novel therapeutic methodPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Daisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Nagasaki University
The elucidation of prion infectious mechanism on host innate immunityPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Daisuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagasaki University
Is a prion hypothesis the validity?: The real pathogen explored from the host innate immune systemsPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Daisuke
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagasaki University
Development of newly prion-vaccine for practical applicationPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Ishibashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Nagasaki University

[Journal Article] RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation2023
- Author(s)
  Nishinakagawa Takuya、Hazekawa Mai、Hosokawa Masato、Ishibashi Daisuke
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 27 Issue: 3 Pages: 62-62
- DOI
  10.3892/mmr.2023.12949
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-22K19497, KAKENHI-PROJECT-23K24250, KAKENHI-PROJECT-23K28190
[Journal Article] Development of an Organ-Directed Exosome-Based siRNA-Carrier Derived from Autologous Serum for Lung Metastases and Testing in the B16/BL6 Spontaneous Lung Metastasis Model2022
- Author(s)
  Hazekawa Mai、Nishinakagawa Takuya、Hosokawa Masato、Ishibashi Daisuke
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 4 Pages: 815-815
- DOI
  10.3390/pharmaceutics14040815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19497, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-23K24250
[Journal Article] Antimicrobial Activities of LL37 Fragment Mutant-Poly (Lactic-Co-Glycolic) Acid Conjugate Against Staphylococcus aureus, Escherichia coli, and Candida albicans2021
- Author(s)
  Takeshi Mori, Miyako Yoshida, Mai Hazekawa, Daisuke Ishibashi, Yoshiro Hatanaka, Toshihiro Nagao, Rie Kakehashi, Honami Kojima, Rio Uno, Minoru Ozeki, Ikuo Kawasaki, Taku Yamashita, Junichi Nishikawa, and Takahiro Uchida
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 10 Pages: 5097-5107
- DOI
  10.3390/ijms22105097
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05426, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-20K07214, KAKENHI-PROJECT-20H04285
[Journal Article] Targeted Delivery of Miconazole Employing LL37 Fragment Mutant Peptide CKR12-Poly (Lactic-Co-Glycolic) Acid Polymeric Micelles2021
- Author(s)
  Takeshi Mori, Miyako Yoshida, Mai Hazekawa, Daisuke Ishibashi, Yoshiro Hatanaka, Rie Kakehashi, Makoto Nakagawa, Toshihiro Nagao, Miki Yoshii, Honami Kojima, Rio Uno, and Takahiro Uchida
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 21 Pages: 12056-12069
- DOI
  10.3390/ijms222112056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05426, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-20K07214, KAKENHI-PROJECT-20H04285
[Journal Article] Enhancing the anticancer efficacy of a LL-37 peptide fragment analog using peptide-linked PLGA conjugate micelles in tumor cells2021
- Author(s)
  Mori Takeshi、Hazekawa Mai、Yoshida Miyako、Nishinakagawa Takuya、Uchida Takahiro、Ishibashi Daisuke
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 606 Pages: 120891-120891
- DOI
  10.1016/j.ijpharm.2021.120891
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-20K07214, KAKENHI-PROJECT-20H04285
[Journal Article] Preparation of siRNA-PLGA/Fab'-PLGA mixed micellar system with target cell-specific recognition2021
- Author(s)
  Hazekawa Mai、Nishinakagawa Takuya、Mori Takeshi、Yoshida Miyako、Uchida Takahiro、Ishibashi Daisuke
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16789-16789
- DOI
  10.1038/s41598-021-96245-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-20K07214, KAKENHI-PROJECT-20H04285
[Journal Article] Liquid-liquid phase separation of full-length prion protein initiates conformational conversion in vitro2021
- Author(s)
  Hiroya Tange, Daisuke Ishibashi, Takehiro Nakagaki, Yuzuru Taguchi, Yuji O Kamatari, Hiroki Ozawa, Noriyuki Nishida
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100367-100367
- DOI
  10.1016/j.jbc.2021.100367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-20K06390, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21396
[Journal Article] Dextran sulphate inhibits an association of prions with plasma membrane at the early phase of infection2021
- Author(s)
  Takayuki Fuse, Takehiro Nakagaki, Takujiro Homma, Hiroya Tange, Naohiro Yamaguchi, Ryuichiro Atarashi, Daisuke Ishibashi, Noriyuki Nishida
- Journal Title
  
  Neuroscience research
  
  Volume: S0168-0102(21) Pages: 00018-3
- DOI
  10.1016/j.neures.2021.01.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21396
[Journal Article] Prion protein interacts with the metabotropic glutamate receptor 1 and regulates the organization of Ca2+ signaling2020
- Author(s)
  Matsubara Takehiro、Satoh Katsuya、Homma Takujiro、Nakagaki Takehiro、Yamaguchi Naohiro、Atarashi Ryuichiro、Sudo Yuka、Uezono Yasuhito、Ishibashi Daisuke、Nishida Noriyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 525 Issue: 2 Pages: 447-454
- DOI
  10.1016/j.bbrc.2020.02.102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07404, KAKENHI-PROJECT-17K16126, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-20H04285
[Journal Article] Novel Compounds Identified by Structure-Based Prion Disease Drug Discovery Using In Silico Screening Delay the Progression of an Illness in Prion-Infected Mice2020
- Author(s)
  Daisuke Ishibashi, Takeshi Ishikawa, Satoshi Mizuta, Hiroya Tange, Takehiro Nakagaki, Tsuyoshi Hamada, Noriyuki Nishida
- Journal Title
  
  Neurotherapeutics
  
  Volume: 17(4) Issue: 4 Pages: 1836-1849
- DOI
  10.1007/s13311-020-00903-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-18K11536, KAKENHI-PROJECT-20H04285
[Journal Article] Generation, optimization and characterization of novel anti-prion compounds2020
- Author(s)
  Andrea Altieri, Evgeny A Spiridonov, Semen I Sivtzev, Daisuke Ishibashi, Silvia Biggi, Noriyuki Nishida, Emiliano Biasini, Alexander V Kurkin
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28(21) Issue: 21 Pages: 115717-115717
- DOI
  10.1016/j.bmc.2020.115717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-20H04285
[Journal Article] Administration of FK506 from Late Stage of Disease Prolongs Survival of Human Prion-Inoculated Mice2020
- Author(s)
  Takehiro Nakagaki, Daisuke Ishibashi, Tsuyoshi Mori, Yukiko Miyazaki, Hanae Takatsuki, Hiroya Tange, Yuzuru Taguchi, Katsuya Satoh, Ryuichiro Atarashi, Noriyuki Nishida
- Journal Title
  
  Neurotherapeutics
  
  Volume: 17(4) Issue: 4 Pages: 1850-1860
- DOI
  10.1007/s13311-020-00870-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-20K07807, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-20H04285
[Journal Article] Type I interferon protects neurons from prions in in vivo models2019
- Author(s)
  Ishibashi Daisuke、Homma Takujiro、Nakagaki Takehiro、Fuse Takayuki、Sano Kazunori、Satoh Katsuya、Mori Tsuyoshi、Atarashi Ryuichiro、Nishida Noriyuki
- Journal Title
  
  Brain
  
  Volume: 142 Issue: 4 Pages: 1035-1050
- DOI
  10.1093/brain/awz016
- NAID
  120006987735
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10022, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-17K16126
[Journal Article] Protective Role of the Host Innate Immune System in Prion Pathogenesis2019
- Author(s)
  Daisuke Ishibashi
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 7 Pages: 993-998
- DOI
  10.1248/yakushi.18-00165-2
- NAID
  130007670790
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-07-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07844
[Journal Article] A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques2019
- Author(s)
  Yamaguchi Keiichi、Kamatari Yuji O.、Ono Fumiko、Shibata Hiroaki、Fuse Takayuki、Elhelaly Abdelazim Elsayed、Fukuoka Mayuko、Kimura Tsutomu、Hosokawa-Muto Junji、Ishikawa Takeshi、Tobiume Minoru、Takeuchi Yoshinori、Matsuyama Yutaka、Ishibashi Daisuke、Nishida Noriyuki、Kuwata Kazuo
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 3 Issue: 3 Pages: 206-219
- DOI
  10.1038/s41551-019-0349-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11536, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19H03476
[Journal Article] Postmortem Quantitative Analysis of Prion Seeding Activity in the Digestive System2019
- Author(s)
  Satoh K, Fuse T, Nonaka T, Dong T, Takao M, Nakagaki T, Ishibashi D, Taguchi Y, Mihara B, Iwasaki Y, Yoshida M, Nishida N.
- Journal Title
  
  Molecules.
  
  Volume: 24(24) Issue: 24 Pages: 4601-4601
- DOI
  10.3390/molecules24244601
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-17K16126
[Journal Article] Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC2017
- Author(s)
  Sano Kazunori、Atarashi Ryuichiro、Satoh Katsuya、Ishibashi Daisuke、Nakagaki Takehiro、Iwasaki Yasushi、Yoshida Mari、Murayama Shigeo、Mishima Kenichi、Nishida Noriyuki
- Journal Title
  
  Molecular Neurobiology
  
  Volume: - Issue: 5 Pages: 3916-3930
- DOI
  10.1007/s12035-017-0624-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07042, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K16126
[Journal Article] Structure-based drug discovery for combating influenza virus by targeting the PA?PB1 interaction2017
- Author(s)
  Watanabe Ken、Ishikawa Takeshi、Otaki Hiroki、Mizuta Satoshi、Hamada Tsuyoshi、Nakagaki Takehiro、Ishibashi Daisuke、Urata Shuzo、Yasuda Jiro、Tanaka Yoshimasa、Nishida Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 9500-9500
- DOI
  10.1038/s41598-017-10021-w
- NAID
  120006987424
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16K00853, KAKENHI-PROJECT-16K07042, KAKENHI-PROJECT-17K16126, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K08844
[Journal Article] Structure-Based Drug Discovery for Prion Disease Using a Novel Binding Simulation.2016
- Author(s)
  Ishibashi D, Nakagaki T, Ishikawa T, Atarashi R, Watanabe K, Cruz FA, Hamada T, Nishida N.
- Journal Title
  
  EBioMedicine.
  
  Volume: 9 Pages: 238-249
- DOI
  10.1016/j.ebiom.2016.06.010
- NAID
  120006987627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04269, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16K07042
[Journal Article] A direct assessment of human prion adhered to steel wire using real-time quaking-induced conversion.2016
- Author(s)
  Mori T, Atarashi R, Furukawa K, Takatsuki H, Satoh K, Sano K, Nakagaki T, Ishibashi D, Ichimiya K, Hamada M, Nakayama T, Nishida N.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 24993-24993
- DOI
  10.1038/srep24993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04269, KAKENHI-PROJECT-26305030, KAKENHI-PROJECT-26461507, KAKENHI-PROJECT-16K07042
[Journal Article] Conformational properties of prion strains can be transmitted to recombinant prion protein fibrils in real-time quaking-induced conversion.2014
- Author(s)
  Sano K, Atarashi R, Ishibashi D, Nakagaki T, Satoh K, Nishida N.
- Journal Title
  
  J Virol
  
  Volume: 88(20) Issue: 20 Pages: 11791-11801
- DOI
  10.1128/jvi.00585-14
- NAID
  120006986372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-25640029, KAKENHI-PROJECT-26305030, KAKENHI-PROJECT-26860671
[Journal Article] Persistent prion infection disturbs the function of Oct-1, resulting in the down-regulation of murine interferon regulatory factor-3.2014
- Author(s)
  Homma T, Ishibashi D, Nakagaki T, Fuse T, Sano K, Satoh K, Atarashi R, Nishida N.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 6006-6006
- DOI
  10.1038/srep06006
- NAID
  120006986450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-25640029, KAKENHI-PROJECT-26305030, KAKENHI-PROJECT-26860671
[Journal Article] Increased expression of p62/SQSTM1 in prion diseases and its association with2014
- Author(s)
  Homma T, Ishibashi D, Nakagaki T, Satoh K, Sano K, Atarashi R, Nishida N.
- Journal Title
  
  Sci Rep.
  
  Volume: 4 Issue: 1 Pages: 4504-4504
- DOI
  10.1038/srep04504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-26305030
[Journal Article] プリオン病の病態解明の進展と治療へのアプローチ2013
- Author(s)
  中垣　岳大、石橋　大輔、西田　教行
- Journal Title
  
  感染　炎症　免疫
  
  Volume: 43(2) Pages: 91-93
- Data Source
  KAKENHI-PROJECT-24591482
[Journal Article] FK506reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.2013
- Author(s)
  Nakagaki T, Satoh K, Ishibashi D, Fuse T, Sano K, Kamatari YO, Kuwata K, Shigematsu K, Iwamaru Y, Takenouchi T, Kitani H, Nishida N, Atarashi R.
- Journal Title
  
  Autophagy.
  
  Volume: 9 Issue: 9 Pages: 1386-1394
- DOI
  10.4161/auto.25381
- NAID
  120006986076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-23370068, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514
[Journal Article] Direct evidence of generation and accumulation ofβ-sheet-rich prion protein in ScN2a cells de novo illuminated by human IgG1 antibody recognizingβ-form but notα-form of prion protein2012
- Author(s)
  Kubota T, Hamazoe Y, Hashiguchi S, Ishibashi D, Akasaka K, Nishida N, Katamine S, Sakaguchi S, Kuroki R, Nakashima T, Sugimura K.
- Journal Title
  
  J Biol Chem
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] Protective role of MyD88 independent innate immune responses against prion infection.2012
- Author(s)
  Ishibashi D, Atarashi R, Nishida N
- Journal Title
  
  Prion
  
  Volume: 6(5) Issue: 5 Pages: 43-446
- DOI
  10.4161/pri.22579
- NAID
  120006985798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591482
[Journal Article] Direct evidence of generation and accumulation of β-sheet-rich prion protein in ScN2a cells de novo illuminated by human IgG1 antibody recognizing β-form but not α-form of prion protein2012
- Author(s)
  Toshiya Kubota, Yuta Hamazoe, Shuhei Hashiguchi, Daisuke Ishibashi, Kazuyuki Akasaka, Noriyuki Nishida, Shigeru Katamine, Suehiro Sakaguchi, Ryota Kuroki, Toshihiro Nakashima, Kazuhisa Sugimura.
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 287巻 Issue: 17 Pages: 14023-14039
- DOI
  10.1074/jbc.m111.318352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790435, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-24591482
[Journal Article] Protective role of interferon regulatory factor3-mediated signaling against prion infection2012
- Author(s)
  Ishibashi D, Atarashi R, Fuse T, Nakagaki T, Yamaguchi N, Satoh K, Honda K, Nishida N.
- Journal Title
  
  J Virol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] Protective role of interferon regulatory factor3-mediated signaling against priori infection2012
- Author(s)
  Ishibashi D, Atarashi R, Fuse T, Nakagaki T, Yamaguchi N, Satoh K, Honda K, Nishida N
- Journal Title
  
  Journal of Virology
  
  Volume: (Epub ahead of print) Issue: 9 Pages: 4947-4955
- DOI
  10.1128/jvi.06326-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J56523, KAKENHI-PROJECT-24591482
[Journal Article] Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.2011
- Author(s)
  Ryuichiro Atarashi, Katsuya Satoh, Kazunori Sano, Takayuki Fuse, Naohiro Yamaguchi, Daisuke Ishibashi, et al.
- Journal Title
  
  Nature medicine
  
  Volume: 17 Pages: 175-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] Antigenic mimicry-mediated anti-prion effects induced by bacterial enzyme succinylarginine dihydrolase in mice2011
- Author(s)
  Ishibashi D, Yamanaka H, Mori T, Yamaguchi N, Yamaguchi Y, Nishida N, Sakaguchi S
- Journal Title
  
  Vaccine
  
  Volume: 29(50) Issue: 50 Pages: 9321-9328
- DOI
  10.1016/j.vaccine.2011.10.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] Antigenic mimicry-mediated anti-prion effects induced by bacterial enzyme succinylarginine dihydrolase in mice2011
- Author(s)
  Ishibashi D, Yamanaka H, Mori T, Yamaguchi N, Yamaguchi Y, Nishida N, Sakaguchi S.
- Journal Title
  
  Vaccine
  
  Volume: 29(50) Pages: 9321-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion2011
- Author(s)
  Atarashi R, Satoh K, Sano K, Fuse T, Yamaguchi N, Ishibashi D, Matsubara T, Nakagaki T, Yamanaka H, Shirabe S, Yamada M, Mizusawa H, Kitamoto T, Klug G, McGlade A, Collins SJ, Nishida N.
- Journal Title
  
  Nat Med
  
  Volume: 17(2) Pages: 175-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] 「プリオン仮説」の証明はどこまで進んだのか? Today, How much do we know now about the prion theory2010
- Author(s)
  石橋大輔
- Journal Title
  
  最新医学
  
  Volume: 65巻10号 Pages: 2306-2310
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] 「プリオン仮説」の証明はどこまで進んだのか?2010
- Author(s)
  石橋大輔
- Journal Title
  
  最新医学
  
  Volume: 65 Pages: 2306-2310
- NAID
  40017344503
- Data Source
  KAKENHI-PROJECT-22790955
[Journal Article] Dominant-negative Effects of the N-terminal Half of Prion Protein on Neurotoxicity of Prion Protein-like Protein/Doppel in Mice2008
- Author(s)
  Daisuke Yoshikawa, Naohiro Yamaguchi, Daisuke Ishibashi, Hitoki Yamanaka, Nobuhiko Okimura, Yoshitaka Yamaguchi, Tsuyoshi Mori, Hironori Miyata, Kazuto Shigemats, Sigeru Katamine, Suehiro Sakaguchi
- Journal Title
  
  The Journal of Biological Chemistry 283(35)
  
  Pages: 24202-24211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790613
[Patent] プリオン病治療薬2018
- Inventor(s)
  石橋大輔、西田教行、水田賢志、石川岳志
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-177224
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K07042
[Patent] プリオン病予防・治療剤2016
- Inventor(s)
  石橋大輔、西田教行、中垣岳大、濱田剛、石川岳志
- Industrial Property Rights Holder
  石橋大輔、西田教行、中垣岳大、濱田剛、石川岳志
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-170349
- Filing Date
  2016-08-31
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] K562細胞に対する機能性マウスモノクローナル抗体8-11G-7の樹立2024
- Author(s)
  作元亮介、池田葵、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] 腸骨リンパ節法を用いたプリオンタンパク質に対するラットモノクローナル抗体の作製2024
- Author(s)
  鈴木菜々、立野正浩、松浦早希、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] プリオンタンパク質に対するラットモノクローナル抗体の樹立2024
- Author(s)
  松浦早希、立野正浩、鈴木菜々、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] 側鎖結晶性ブロック共重合体を基盤としたミセルの薬物送達キャリアへの応用2024
- Author(s)
  船津百加、櫨川舞、渡瀬大輔、西中川拓也、細川雅人、八尾滋、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] プリオンタンパク質に対するラットモノクローナル抗体の樹立2024
- Author(s)
  松浦早希、立野正浩、鈴木菜々、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] 側鎖結晶性ブロック共重合体を基盤とした見せるの薬物送達キャリアへの応用2024
- Author(s)
  船津百加、櫨川舞、渡瀬大輔、西中川拓也、細川雅人、八尾滋、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] 側鎖結晶性ブロック共重合体の表面改質を利用した生分解性培養シートの開発2024
- Author(s)
  藪本こころ、櫨川舞、渡瀬大輔、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] プリオンタンパク質に対するラットモノクローナル抗体の樹立2024
- Author(s)
  松浦早希、立野正浩、鈴木菜々、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] プリオンタンパク分解機構におけるユビキチン・プロテアソーム系の関与2024
- Author(s)
  池田葵、作元亮介、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] K562細胞に対する機能性マウスモノクローナル抗体8-11G-7の樹立2024
- Author(s)
  作元亮介、池田葵、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] 腸骨リンパ節法を用いたプリオンタンパク質に対するラットモノクローナル抗体の作製2024
- Author(s)
  鈴木菜々、立野正浩、松浦早希、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] 腸骨リンパ節法を用いたプリオンタンパク質に対するラットモノクローナル抗体の作製2024
- Author(s)
  鈴木菜々、立野正浩、松浦早希、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] K562細胞に対する機能性マウスモノクローナル抗体8-11G-7の樹立2024
- Author(s)
  作元亮介、池田葵、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] 側鎖結晶性ブロック共重合体の表面改質を利用した生分解性培養シートの開発2024
- Author(s)
  藪本こころ、櫨川舞、渡瀬大輔、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] 側鎖結晶性ブロック共重合体を基盤としたミセルの薬物送達キャリアへの応用2024
- Author(s)
  船津百加、櫨川舞、渡瀬大輔、西中川拓也、細川雅人、八尾滋、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] 側鎖結晶性ブロック共重合体の表面改質を利用した生分解性培養シートの開発2024
- Author(s)
  藪本こころ、櫨川舞、渡瀬大輔、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] プリオンタンパク分解機構におけるユビキチン・プロテアソーム系の関与2024
- Author(s)
  池田葵、作元亮介、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] 腫瘍関連抗原22-1-1抗原の生物学的解析2023
- Author(s)
  小野菜々子、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] RCAS1はp38リン酸化の低下を介して細胞形態変化を誘導する2023
- Author(s)
  西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] Screening prion protein binders using surface plasmon resonance biosensor as pre-clinical candidates2023
- Author(s)
  Hazekawa M, Ishibashi D, Altieri A, Spiridonov EA, Dmitriev NA, Lukyanenko ER, Biasini E, Kurkin AV
- Organizer
  Asian Pacific Prion Symposium 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] 合成タウ線維脳内接種による3リピートタウ蓄積モデルマウスの検討　Spreading of 3-repeat tau pathology in tau knock-in mice2023
- Author(s)
  Masuda-Suzukake M, Hasegawa M, Ishibashi D, Hosokawa M
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] がん細胞株培養上清中の細胞傷害活性因子2023
- Author(s)
  前野史佳、西中川拓也、甲斐茜、内原佑月、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] がん細胞株培養上清中の細胞傷害活性因子2023
- Author(s)
  前野史佳、西中川拓也、甲斐茜、内原佑月、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] Screening prion protein binders using surface plasmon resonance biosensor as pre-clinical candidates2023
- Author(s)
  Hazekawa M, Ishibashi D, Altieri A, Spiridonov EA, Dmitriev NA, Lukyanenko ER, Biasini E, Kurkin AV
- Organizer
  Asian Pacific Prion Symposium 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] Screening prion protein binders using surface plasmon resonance biosensor as pre-clinical candidates2023
- Author(s)
  Hazekawa M, Ishibashi D, Altieri A, Spiridonov EA, Dmitriev NA, Lukyanenko ER, Biasini E, Kurkin AV
- Organizer
  Asian Pacific Prion Symposium 2023
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] 合成タウ線維脳内接種による3リピートタウ蓄積モデルマウスの検討2023
- Author(s)
  Masuda-Suzukake M, Hasegawa M, Ishibashi D, Hosokawa M
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] Spreading of 3-repeat tau pathology in tau knock-in mice　合成タウ線維脳内接種による3リピートタウ蓄積モデルマウスの検討2023
- Author(s)
  Masuda-Suzukake M, Hasegawa M, Ishibashi D, Hosokawa M
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] がん細胞培養上清に含まれる細胞障害活性因子2023
- Author(s)
  西中川拓也, 細川雅人, 石橋大輔
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] 腫瘍関連抗原22-1-1抗原の生物学的解析2023
- Author(s)
  小野菜々子、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K19497
[Presentation] がん細胞株培養上清中の細胞傷害活性因子2023
- Author(s)
  前野史佳、西中川拓也、甲斐茜、内原佑月、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] RCAS1はp38リン酸化の低下を介して細胞形態変化を誘導する2023
- Author(s)
  西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] RCAS1はp38リン酸化の低下を介して細胞形態変化を誘導する2023
- Author(s)
  西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] 腫瘍関連抗原22-1-1抗原の生物学的解析2023
- Author(s)
  小野菜々子、西中川拓也、細川雅人、石橋大輔
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24250
[Presentation] がん細胞培養上清に含まれる細胞障害活性因子2023
- Author(s)
  西中川拓也, 細川雅人, 石橋大輔
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K28190
[Presentation] 抗菌ペプチドフラグメント変異体CKR12－PLGAコンジュゲートによる抗真菌活性の向上2022
- Author(s)
  吉田都、森健、櫨川舞、石橋大輔、畠中芳郎、永尾寿浩、懸橋理枝、吉井未貴、中川充、小島穂菜美、宇野莉央、内田享弘
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] 側鎖結晶性ブロック共重合体の温度応答性を利用した細胞シート培養システムの構築2022
- Author(s)
  櫨川舞、西中川拓也、細川雅人、八尾滋、石橋大輔
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] 抗菌ペプチドフラグメント変異体CKR12－PLGAコンジュゲートによる抗真菌活性の向上2022
- Author(s)
  吉田都、森健、櫨川舞、石橋大輔、畠中芳郎、永尾寿浩、懸橋理枝、吉井未貴、中川充、小島穂菜美、宇野莉央、内田享弘
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] 側鎖結晶性ブロック共重合体の温度応答性を利用した細胞シート培養システムの構築2022
- Author(s)
  櫨川舞、西中川拓也、細川雅人、八尾滋、石橋大輔
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] 腫瘍関連抗原RCAS1の生物学的機能解析2022
- Author(s)
  西中川拓也、櫨川舞、細川雅人、石橋大輔
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] 腫瘍関連抗原RCAS1の生物学的機能解析2022
- Author(s)
  西中川拓也、櫨川舞、細川雅人、石橋大輔
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] RCAS1発現による細胞形態変化へのp38シグナルの関与2021
- Author(s)
  西中川拓也、櫨川舞、細川雅人、石橋大輔
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] 抗菌ペプチドフラグメント誘導体およびPLGAとのコンジュゲートによる抗真菌活性2021
- Author(s)
  森健、吉田都、櫨川舞、石橋大輔、畠中芳郎、永尾寿浩、懸橋理枝、小島穂菜美、小関稔、川崎郁勇、山下沢、西川淳一、内田享弘
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] ミコナゾールを封入した抗菌ペプチド-乳酸・グリコール酸共重合体コンジュゲートミセルの調製および抗真菌活性評価2021
- Author(s)
  森健、吉田都、櫨川舞、小島穂菜美、宇野莉央、吉井未貴、永尾寿浩、畠中芳郎、中川充、懸橋理枝、石橋大輔、内田享弘
- Organizer
  第71回日本薬学会関西支部
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] RCAS1発現による細胞形態変化へのp38シグナルの関与2021
- Author(s)
  西中川拓也、櫨川舞、細川雅人、石橋大輔
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] ミコナゾールを封入した抗菌ペプチド-乳酸・グリコール酸共重合体コンジュゲートミセルの調製および抗真菌活性評価2021
- Author(s)
  森健、吉田都、櫨川舞、小島穂菜美、宇野莉央、吉井未貴、永尾寿浩、畠中芳郎、中川充、懸橋理枝、石橋大輔、内田享弘
- Organizer
  第71回日本薬学会関西支部
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] 抗がんペプチド含有生分解性ミセルの抗がん活性に関する検討2021
- Author(s)
  櫨川舞、森健、吉田都、西中川拓也、内田享弘、石橋大輔
- Organizer
  第141年会日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] 抗菌ペプチドフラグメント誘導体およびその生分解性ミセルの抗がん活性に関する検討2021
- Author(s)
  櫨川舞、森健、吉田都、西中川拓也、内田享弘、石橋大輔
- Organizer
  第141年会日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] プリオン病治療のための蛋白構造を安定化させる低分子化合物の開発2021
- Author(s)
  石橋大輔
- Organizer
  国立研究開発法人日本医療研究開発機構新的医療技術創出拠点令和2年度成果報告会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] プリオン病治療のための蛋白構造を安定化させる低分子化合物の開発2021
- Author(s)
  石橋大輔
- Organizer
  国立研究開発法人日本医療研究開発機構　新的医療技術創出拠点　令和2年度成果報告会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] ペプチド－PLGAハイブリッドミセルを用いた活性ペプチドの抗腫瘍効果増強作用2021
- Author(s)
  櫨川舞、西中川拓也、細川雅人、石橋大輔
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] ペプチド－PLGAハイブリッドミセルを用いた活性ペプチドの抗腫瘍効果増強作用2021
- Author(s)
  櫨川舞、西中川拓也、細川雅人、石橋大輔
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] プリオン病治療のための蛋白構造を安定化させる低分子化合物の開発2021
- Author(s)
  石橋大輔
- Organizer
  第8回TR推進合同フォーラム・ライフサイエンス技術交流会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] プリオン病治療のための蛋白構造を安定化させる低分子化合物の開発2021
- Author(s)
  石橋大輔
- Organizer
  第８回TR推進合同フォーラム・ライフサイエンス技術交流会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] 抗がんペプチド含有生分解性ミセルの抗がん活性に関する検討2021
- Author(s)
  櫨川舞、森健、吉田都、西中川拓也、内田享弘、石橋大輔
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] 抗菌ペプチドフラグメント誘導体およびPLGAとのコンジュゲートによる抗真菌活性2021
- Author(s)
  森健、吉田都、櫨川舞、石橋大輔、畠中芳郎、永尾寿浩、懸橋理枝、小島穂菜美、小関稔、川崎郁勇、山下沢、西川淳一、内田享弘
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] がん細胞株培養上清中に含まれる細胞傷害性因子2021
- Author(s)
  西中川拓也、櫨川舞、石橋大輔
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] 抗菌ペプチドフラグメント誘導体およびその生分解性ミセルの抗がん活性に関する検討2021
- Author(s)
  櫨川舞、森健、吉田都、西中川拓也、内田享弘、石橋大輔
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] 抗菌ペプチドフラグメント誘導体およびPLGAとのコンジュゲートによる抗菌活性2021
- Author(s)
  森健、吉田都、小島穂菜美、櫨川舞、石橋大輔、小関稔、川崎郁勇、山下沢、西川淳一、畠中芳郎、永尾寿浩、懸橋理枝、内田享弘
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] がん細胞株培養上清に含まれる細胞傷害性因子の同定2020
- Author(s)
  西中川拓也、櫨川舞、石橋大輔
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04285
[Presentation] Identification of cytotoxic factor contained in tumor cell line supernatants がん細胞株培養上清に含まれる細胞障害性因子の同定2020
- Author(s)
  西中川拓也、櫨川舞、石橋大輔
- Organizer
  第79回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] プリオン蛋白の液相分離2019
- Author(s)
  丹下寛也, 中垣岳大, 田口謙, 石橋大輔, 西田教行
- Organizer
  第72回　日本細菌学会九州支部総会第56回　日本ウイルス学会九州支部総会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] プリオン感染におけるI型インターフェロン受容体の影響 Effect of type I interferon receptor against prion infection2019
- Author(s)
  Daisuke Ishibashi, Takehiro Nakagaki, Noriyuki Nishida
- Organizer
  第42回日本分子生物学会年会（MBSJ2019）
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] I型インターフェロン受容体のプリオン感染における役割 Type I interferon receptor subunit (IFNAR1) suppresses prion infection2019
- Author(s)
  Daisuke Ishibashi, Takehiro Nakagaki, Noriyuki Nishida
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07844
[Presentation] 炭酸水素カルシウムメゾ構造体によるプリオン不活性化能の検討2018
- Author(s)
  中垣岳大, 的場苑子, 石橋大輔, 西田教行
- Organizer
  第７１回　日本細菌学会九州支部総会・第５５回　日本ウイルス学会九州支部総会
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] インフルエンザウイルス複製を標的とした蛋白質－蛋白質相互作用阻害剤の開発2018
- Author(s)
  渡邊健, Juliann Nzembi Makau, 石川岳志, 大滝大樹, 水田賢志, 中垣岳大, 石橋大輔, 浦田秀造, 安田二朗, 西田教行
- Organizer
  第７１回　日本細菌学会九州支部総会・第５５回　日本ウイルス学会九州支部総会
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] プリオン病におけるインシリコ創薬開発2018
- Author(s)
  石橋大輔
- Organizer
  第８回認知症研究を知る若手研究者の集まり2018
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] in silicoプリオン病創薬における薬効特異性の評価2018
- Author(s)
  石橋大輔、中垣岳大、石川岳志、水田賢志、濱田剛、西田教行
- Organizer
  生体機能と創薬シンポジウム２０１８
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] I型インターフェロンのプリオン感染に対する抑制作用 Type I interferon suppresses prion infection2018
- Author(s)
  石橋大輔, 中垣岳大, 西田教行
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] Prion-like propagation of filamentous tau inclusions in cultured neuronal cells2018
- Author(s)
  Gen Matsumoto, Naruhiko Sahara, Daisuke Ishibashi, Noriyuki Nishida, Nozomu Mori
- Organizer
  Asian pacific prion symposium 2018 (APPS2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] プリオン感染における自然免疫機構の役割 Protective role of host innate immunity system in prion pathogenesis2018
- Author(s)
  Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Kazunori Sano, Kenya Honda, Ryuichiro Atarashi, Noriyuki Nishida
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] プリオン病におけるインシリコ創薬開発2017
- Author(s)
  石橋大輔、石川岳志、中垣岳大、丹下寛也、西田教行
- Organizer
  第70回日本細菌学会九州支部総会、第54回日本ウイルス学会九州支部総会
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] Evaluation of drug specificity for anti-prion compounds selective by structure-based binding simulation　in silico プリオン病創薬における薬効特異性の評価2017
- Author(s)
  Daisuke Ishibashi, Takehiro Nakagaki, Takeshi Ishikawa, Tsuyoshi Hamada, Noriyuki Nishida
- Organizer
  2017年度生命科学系学会合同年次大会 (ConBio2017), 第40回日本分子生物学会年会, 第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] Wire-QuIC: A new detection system of human prion2016
- Author(s)
  Tsuyoshi Mori, Ryuichiro Atarashi, Hanae Takatsuki, Katsuya Satoh, Takehiro Nakagaki, Daisuke Ishibashi, Noriyuki Nishida
- Organizer
  Prion2016 & APPS2016
- Place of Presentation
  日本教育会館・一橋ホール（東京都・千代田区）
- Year and Date
  2016-05-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] Wire-QuIC reaction can detect abnormal human prion seeds from contaminated stainless steel-wire. Wire-QuICはステンレススチールワイヤー上に付着したプリオンを検出できる2016
- Author(s)
  Tsuyoshi Mori, Ryuichiro Atarashi, Katsuya Satoh, Daisuke Ishibashi, Takehiro Nakagaki, Noriyuki Nishida
- Organizer
  第64回日本ウイルス学会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] Prion strain-dependent effect of macroautophagy on abnormal prion protein degradation2016
- Author(s)
  Daisuke Ishibashi, Takehiro Nakagaki, Ryuichiro Atarashi, Noriyuki Nishida
- Organizer
  Prion2016 & APPS2016
- Place of Presentation
  日本教育会館・一橋ホール（東京都・千代田区）
- Year and Date
  2016-05-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] Structure-based drug discovery for prion disease by using a novel binding simulation on the graphics processing unit intensive supercomputer2016
- Author(s)
  Daisuke Ishibashi, Takehiro Nakagaki, Takeshi Ishikawa, Ryuichiro Atarashi, Tsuyoshi Hamada, Noriyuki Nishida
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K07042
[Presentation] 選択的オートファジーによる異常型プリオン蛋白（PrPSc）の認識および分解　Sequestsome-1/p62 enhances clearance of pathogenic prion protein2013
- Author(s)
  本間拓二郎, 石橋大輔, 中垣岳大, 新竜一郎, 西田教行
- Organizer
  第25回　高遠シンポジウム
- Place of Presentation
  延暦寺会館　(比叡山)（滋賀県大津市）
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] I型インターフェロンを介した宿主自然免疫応答におけるプリオン感染抑制機構2013
- Author(s)
  石橋　大輔, 本間　拓二郎, 中垣　岳大, 佐野　和憲, 本田　賢也, 新　竜一郎, 西田　教行
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場　（神戸市）
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] p62/SQSTM1 promotes the sequestration and clearance of pathogenic prion protein2013
- Author(s)
  Takujiro Homma, Daisuke Ishibashi, Takehiro Nakagaki, Ryuichiro Atarashi, Noriyuki Nishida
- Organizer
  expanding prion horizons　-prion reseach center-
- Place of Presentation
  University center for the arts fort collins, Colorad, USA
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] Type I interferon signal pathway of host innate immune response regulates prion infection2013
- Author(s)
  Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Kazunori Sano, Kenya Honda, Ryuichiro Atarashi, Noriyuki Nishida
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] FK506 reduces abnomal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice2013
- Author(s)
  Takehiro Nakagaki, Katsuya Satoh, Daisuke Ishibashi, Takayuki Fuse, Kazunori Sano, Yuji O. Kamatari, Kazuo Kuwata, Kazuo Shigematsu, Yoshifumi Iwamaru, Takato Takenouchi, Hiroshi Kitani, Noriyuki Nishida, Ryuichiro Atarashi
- Organizer
  Asian pacific prion symposium 2013 in Nagasaki(APPS2013)
- Place of Presentation
  ハウステンボス（長崎県佐世保市）
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] p62/SQSTM1 promotes the sequestration and clearance of pathogenic prion protein2013
- Author(s)
  Takujiro Homma, Daisuke Ishibashi, Takehiro Nakagaki, Ryuichiro Atarashi and Noriyuki Nishida
- Organizer
  Asian pacific prion symposium 2013 in Nagasaki(APPS2013)
- Place of Presentation
  ハウステンボス（長崎県佐世保市）
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] Analysis of Interferon Regulatory Factor-3 (IRF-3) Promoter: Implications for Prion Infection2013
- Author(s)
  Takujiro Homma, Daisuke Ishibashi, Ryuichiro Atarashi and Noriyuki Nishida
- Organizer
  Asian pacific prion symposium 2013 in Nagasaki(APPS2013)
- Place of Presentation
  ハウステンボス（長崎県佐世保市）
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] Type I IFN signal pathway of host innate immune response regulates prion infection2013
- Author(s)
  Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Kazunori Sano, Kenya Honda, Ryuichiro Atarashi, Noriyuki Nishida
- Organizer
  Asian pacific prion symposium 2013 in Nagasaki(APPS2013)
- Place of Presentation
  ハウステンボス（長崎県佐世保市）
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] セクエストソーム１蛋白によるプリオン凝集体の認識.2013
- Author(s)
  本間拓二郎, 石橋大輔, 中垣岳大, 西田教行.
- Organizer
  感染症若手フォーラム.
- Place of Presentation
  北広島クラッセホテル（北海道）.
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] プリオン阻害活性を示す抗プリオンタンパク質抗体による非感染神経芽腫細胞内でのPK抵抗性プリオンオリゴマーの生成.2012
- Author(s)
  濱添勇太, 橋口周平, 杉村和久, 石橋大輔, 西田教行.
- Organizer
  第85回日本生化学会大会.
- Place of Presentation
  マリンメッセ福岡.
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] 異常型プリオン蛋白の細胞内代謝機構の解明2012
- Author(s)
  本間拓二郎、石橋大輔、西田教行
- Organizer
  第36回長崎感染症研究会
- Place of Presentation
  長崎大学(良順会館)
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] Protective role of host innate immune response against prion pathogen.2012
- Author(s)
  Daisuke Ishibashi.
- Organizer
  The 6th Nagasaki Symposium on Emerging Infectious Diseases and the 11th Nagasaki-Singapore Medical Symposium.
- Place of Presentation
  Rypjun auditorium Nagasaki university
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] Increased expression of Sequestosome-1 in prion disease and its association with pathogenic prion protein.2012
- Author(s)
  Takujiro Homma, Daisuke Ishibashi, Ryuichiro Atarashi, Noriyuki Nishida.
- Organizer
  Asian Pacific Prion Symposium 2012.
- Place of Presentation
  Pacifico Yokohama.
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] Analysis of murine interferon regulatory factor-3 (IRF-3) promoter2011
- Author(s)
  Takujiro Homma, Daisuke Ishibashi, Noriyuki Nishida
- Organizer
  IUMS 2011 (Meetings of the Three Divisions of the International Union of Microbiological Societies 2011)
- Place of Presentation
  Sapporo (Japan)
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] プリオン感染におけるInterferon regulatory factor-3(IRF-3)遺伝子の発現抑制機序の解明2011
- Author(s)
  本間拓二郎、石橋大輔、西田教行
- Organizer
  第35回長崎感染症研究会
- Place of Presentation
  長崎大学(良順会館)
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] 細菌由来の蛋白succinylarginine dihydrolaseの免疫によるプリオン病の予防効果. Immunization with bacterial enzyme succinylarginine dihydrolase induces antigenic mimicry-mediated anti-prion effects in mice2011
- Author(s)
  Daisuke Ishibashi, Hitoki Yamanaka, Naohiro Yamaguchi, Yoshitaka Yamaguchi, Noriyuki Nishida. Suehiro Sakaguchi
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] Bio.072 : Protective role of interferon regulatory factor 3-dependent signaling against priori infection2011
- Author(s)
  Daisuke Ishibashi, Noriyuki Nishida
- Organizer
  Prion 2011
- Place of Presentation
  Montreal (Canada)
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] 細菌由来の蛋白succinylarginine dihydrolaseの免疫によるプリオン病の予防効果/Immunization with bacterial enzyme succinylarginine dihydrolase induces antigenic mimicrymediated anti-prion effects in mice2011
- Author(s)
  石橋大輔, 山中仁木, 山口尚宏, 山口仁孝, 西田教行, 坂口末廣
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] Analysis of murine interferon regulatory factor-3(IRF-3) promoter. IUMS 20112011
- Author(s)
  Takujiro Homma, Daisuke Ishibashi, Noriyuki Nishida
- Organizer
  Meetings of the Three Divisions of the International Union of Microbiological Societies 2011
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] プリオン感染におけるInterferon regulatory factor-3 (IRFL3)遺伝子の発現抑制機序の解明2011
- Author(s)
  本間拓二郎、石橋大輔、西田教行
- Organizer
  第35回長崎感染症研究会
- Place of Presentation
  長崎大学(良順会館)
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] Protective Role of Interferon Regulatory Factor 3-Dependent Signaling Against Prion Infection2011
- Author(s)
  Daisuke Ishibashi, Noriyuki Nishida
- Organizer
  Prion 2011
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] Reconstruction of infectious prion protein in vitro2010
- Author(s)
  Kazunori Sano, ryuichiro atarashi, daisuke ishibashi, naohiro yamaguchi, takayuki fuse, noriyuki nishida
- Organizer
  BMB2010 第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] FK506はプリオン感染マウスの生存期間を延長させる2010
- Author(s)
  中垣岳大, 佐藤克也, 鎌足雄司, 新竜一郎, 石橋大輔, 山口尚宏, 西田教行
- Organizer
  BMB2010 第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] FK506はプリオン感染マウスの生存期間を延長させる2010
- Author(s)
  中垣岳大, 佐藤克也, 鎌足雄司, 新竜一郎, 石橋大輔, 山口尚宏, 西田教行
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] Reconstruction of infectious prion protein in vitro2010
- Author(s)
  Kazunori Sano, Ryuichiro Atarashi, Daisuke Ishibashi, Naohiro Yamaguchi, Takayuki Fuse, Noriyuki Nishida
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790955
[Presentation] プリオン持続感染細胞におけるウイルス感染に対して働く自然免疫機構関連因子の関与2008
- Author(s)
  石橋大輔
- Organizer
  第32回長崎感染症研究会
- Place of Presentation
  長崎大学医学部(良順会館)
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19790613
[Presentation] プリオン持続感染細胞におけるウイルス感染に対して働く自然免疫機構関連因子の関与2008
- Author(s)
  石橋大輔
- Organizer
  第32回長崎感染症研究会
- Place of Presentation
  長崎大学医学部良(順会館)
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19790613
[Presentation] プリオン感染成立における自然免疫機構の関与A role of Innate immunity in Prion pathogen infectious formation2007
- Author(s)
  石橋大輔
- Organizer
  第37回日本免疫学会総会学術集会
- Place of Presentation
  東京(グランドプリンスホテル新高輪)
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19790613
[Presentation] ウイルス感染に対して働く自然免疫機構関連因子とプリオン感染との関与2007
- Author(s)
  石橋大輔
- Organizer
  第55回ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-19790613
[Presentation] プリオン感染成立における自然免疫機構の関与A role of Innate immunity in Prion pathogen infectious formation.2007
- Author(s)
  石橋大輔
- Organizer
  第37回日本免疫学会総会学術集会
- Place of Presentation
  東京(グランドプリンスホテル新高輪)
- Data Source
  KAKENHI-PROJECT-19790613
[Presentation] Metabolism of PrPSc differs depending on prion strains
- Author(s)
  Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Kazunori Sano, Naohiro Yamaguchi, Tsuyoshi Mori, Katsuya Satoh, Ryuichiro Atarashi, Noriyuki Nishida
- Organizer
  Prion2014
- Place of Presentation
  Trieste, Italy
- Year and Date
  2014-05-27 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] Persistent prion infection disturbs the function of Oct-1, resulting in the down-regulation of murine interferon regulatory factor-3
- Author(s)
  Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Noriyuki Nishida.
- Organizer
  第43回日本免疫学会学術集会 The 43rd Annual Meeting of The Japanese Society for Immunology
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] Metabolism of PrPSc differs depending on prion strains
- Author(s)
  Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Ryuichiro Atarashi, Noriyuki Nishida
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] 正常型プリオン蛋白のプロテアソーム分解機構を再考する
- Author(s)
  本間拓二郎、石橋大輔、新竜一郎、西田教行
- Organizer
  第33回分子病理学研究会宮城蔵王シンポジウム
- Place of Presentation
  宮城蔵王ロイヤルホテル、宮城
- Year and Date
  2014-07-25 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] プリオン感染における宿主自然免疫応答の役割 Role of the host innate immune responses against prion pathogenesis
- Author(s)
  石橋　大輔
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] セクエストソーム１蛋白によるプリオン凝集体の認識.
- Author(s)
  本間拓二郎, 石橋大輔, 中垣岳大, 新竜一郎, 西田教行.
- Organizer
  第37回長崎感染症研究会.
- Place of Presentation
  長崎大学(ポンペ会館）.
- Data Source
  KAKENHI-PROJECT-24591482
[Presentation] 病原体プリオンによる転写因子IRF3の発現抑制機構
- Author(s)
  石橋大輔、本間拓二郎、西田教行
- Organizer
  第 67 回日本細菌学会九州支部総会第 51 回日本ウイルス学会九州支部総会
- Place of Presentation
  城山観光ホテル、鹿児島
- Year and Date
  2014-09-05 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24591482

1. Ishikawa Takeshi (80505909)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 水田賢志 (50717618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 鎌足雄司 (70342772)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Nishida Noriyuki (40333520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. 櫨川舞 (10509186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. ATARASHI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
7. NAGAO Toshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 佐藤克也

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
9. 森剛志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 上園保仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 橋口周平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIBASHI Daisuke 石橋 大輔

ISHIBASHI Ishibashi 石橋 大輔

Research Projects

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Co-Researchers

Development of an effective pharmacophore model for chemical chaperones and its application to anti-prion drugs

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難治性疾患を対象とした臓器指向性をもつ次世代核酸医薬の開発Principal Investigator

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病原体プリオンに対する生体防御機構の解明および免疫システムに着目した治療薬の開発Principal Investigator

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Construction of the pharmacophore model of antiprion compounds for development of a novel therapeutic agent

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Investigation of pathological mechanism, and innate immune targeting drug discovery in prion diseasPrincipal Investigator

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Replication of sCJD in vtro

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The elucidation of molecular pathological condition in prion disease: analysis of interferon system to develop novel therapeutic methodPrincipal Investigator

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The elucidation of prion infectious mechanism on host innate immunityPrincipal Investigator

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Is a prion hypothesis the validity?: The real pathogen explored from the host innate immune systemsPrincipal Investigator

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Development of newly prion-vaccine for practical applicationPrincipal Investigator

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[Journal Article] RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation2023

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[Journal Article] Development of an Organ-Directed Exosome-Based siRNA-Carrier Derived from Autologous Serum for Lung Metastases and Testing in the B16/BL6 Spontaneous Lung Metastasis Model2022

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[Journal Article] Antimicrobial Activities of LL37 Fragment Mutant-Poly (Lactic-Co-Glycolic) Acid Conjugate Against Staphylococcus aureus, Escherichia coli, and Candida albicans2021

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ISHIBASHI Daisuke 石橋大輔

ISHIBASHI Ishibashi 石橋大輔