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Watanabe Sugiko  渡邉 すぎ子

… Alternative Names

渡邉 すぎ子  ワタナベ スギコ

WATANABE SUGIKO  渡邉 すぎ子

WATANABE Sugiko  渡邉 すぎ子

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Researcher Number 10433012
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2120-9546
Affiliation (Current) 2025: 熊本大学, 発生医学研究所, 特任准教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 熊本大学, 発生医学研究所, 特定事業研究員
2020: 熊本大学, 発生医学研究所, 特定事業研究員
2015 – 2016: 大阪大学, 微生物病研究所, 准教授
2014: 九州大学, 学内共同利用施設等, 研究員
2009: 熊本大, 助教
2007 – 2008: Kumamoto University, 発生医学研究センター, 助教
Review Section/Research Field
Principal Investigator
Digestive surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Tumor biology
Keywords
Principal Investigator
がん / DNA損傷修復応答 / エピジェネティクス / ターゲットシーケンス / 治療抵抗性 / 乳がん / セルフリーDNA / 全ゲノム解析 / ゲノム不安定性 / 細胞老化 … More / DNA損傷応答 / クロマチン / RB / 上皮間葉転換 / 膵臓癌 / 癌 / HMGA Less
  • Research Projects

    (5 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (4 People)
  •  Analysis of cell-free DNA targeted sequence to develop of novel strategies for endocrine therapy-resistant breast cancerPrincipal Investigator

    • Principal Investigator
      渡邉 すぎ子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kumamoto University
  •  Molecular mechanism of accumulation of cytoplasmic chromatin in senescent cells, related to carcinogenesisPrincipal Investigator

    • Principal Investigator
      Watanabe Sugiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kumamoto University
  •  Molecular research of non-histone lysine methylation in cancer epigenome and its potential as a therapeutic targetPrincipal Investigator

    • Principal Investigator
      WATANABE SUGIKO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Osaka University
      Kyushu University
  •  膵臓癌の癌幹細胞的特性に対する構造的クロマチン因子の役割解明と治療的アプローチPrincipal Investigator

    • Principal Investigator
      渡邉 すぎ子
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  The role of high mobility group A proteins in cancersPrincipal Investigator

    • Principal Investigator
      WATANABE Sugiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University

All 2022 2020 2017 2016 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] 細胞老化と加齢性疾患ー予防・治療標的研究の最前線ー2020

    • Author(s)
      渡邉すぎ子、原英二
    • Journal Title

      基礎老化研究

      Volume: 44 Pages: 31-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07589
  • [Journal Article] 細胞老化の分子メカニズムとその創薬応用の可能性2020

    • Author(s)
      渡邉すぎ子、原英二
    • Journal Title

      老年内科

      Volume: 2 Pages: 601-609

    • Data Source
      KAKENHI-PROJECT-20K07589
  • [Journal Article] The impact of SASP and its potential as a therapeutic target for senescence-associated diseases.2017

    • Author(s)
      Watabnabe, S., Kawamoto, S., Ohtani, N., & Hara, E.
    • Journal Title

      Cancer Science

      Volume: - Issue: 4 Pages: 563-569

    • DOI

      10.1111/cas.13184

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26430116, KAKENHI-PROJECT-16H04699
  • [Journal Article] Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.2016

    • Author(s)
      Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, Oki E, Kitao H, Maehara Y:
    • Journal Title

      Nature Communications

      Volume: [Epub ahead of print] Issue: 1 Pages: 11117-11117

    • DOI

      10.1038/ncomms11117

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25462024, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-15H05792, KAKENHI-PROJECT-26281025, KAKENHI-PROJECT-26430116
  • [Journal Article] TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity.2016

    • Author(s)
      Moudry P, Watanabe K, Wolanin KM, Bartkova J, Wassing IE, Watanabe S., Strauss R, Troelsgaard Pedersen R, Oestergaard VH, Lisby M, Andújar-Sánchez M, Maya-Mendoza A, Esashi F, Lukas J, Bartek J
    • Journal Title

      J Cell Biol.

      Volume: 212 Issue: 3 Pages: 281-288

    • DOI

      10.1083/jcb.201507042

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430116
  • [Journal Article] HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells2009

    • Author(s)
      Watanabe, S., Ueda, Y., Akaboshi, S., Hino, Y., Sekita, Y. and Nakao, M.
    • Journal Title

      Am J Pathol 174

      Pages: 854-868

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790945
  • [Journal Article] HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells2009

    • Author(s)
      Watanabe, S.
    • Journal Title

      American Journal of Pathology 174

      Pages: 854-868

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790945
  • [Journal Article] miRNAとエピジェネティクス2008

    • Author(s)
      渡邉すぎ子、赤星慎一、渡邊丈久、中尾光善
    • Journal Title

      実験医学増刊号 26

      Pages: 1562-1568

    • Data Source
      KAKENHI-PROJECT-19790945
  • [Journal Article] miRNAとエピジェネーティクス2008

    • Author(s)
      渡邉すぎ子
    • Journal Title

      実験医学増刊号 26

      Pages: 1562-1568

    • Data Source
      KAKENHI-PROJECT-19790945
  • [Journal Article] High mobility group protein HMGAl inhibits retinoblastoma protein-mediated cellular GO arrest2007

    • Author(s)
      Ueda, Y., Watanabe, S., Tei. S., Saitoh, N., Kuratsu, J.-I., Nakao, M.
    • Journal Title

      Cancer Science 98

      Pages: 1893-1901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790945
  • [Journal Article] High mobility group protein HMGA1 inhibits retinoblastoma proteinmediated cellular G0 arrest2007

    • Author(s)
      Ueda, Y., Watanabe, S., Tei, S., Saitoh, N., Kuratsu, J. I., Nakao, M.
    • Journal Title

      Cancer Sci 98

      Pages: 1893-901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790945
  • [Presentation] 術前遺伝学的検査の現状と展望~複数の乳がん関連遺伝子変異を疑った症例から学ぶ~2022

    • Author(s)
      渡邉すぎ子、佐々木瑠美、柊中智恵子、後藤理沙、山本豊、大場 隆
    • Organizer
      第28回日本遺伝性腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07589
  • [Presentation] 細胞老化に伴うゲノム不安定性検出を目指した核外ゲノム次世代シーケンスと、そのがんゲノムへのフィードバック解析2020

    • Author(s)
      渡邉すぎ子、山本拓也、原英二
    • Organizer
      日本人類遺伝学会第65回大会
    • Data Source
      KAKENHI-PROJECT-20K07589
  • [Presentation] がん・老化細胞の運命決定におけるDNA損傷応答の役割2016

    • Author(s)
      渡邉すぎ子
    • Organizer
      第5回浜名湖DNA損傷応答ワークショップ
    • Place of Presentation
      静岡県浜松市
    • Year and Date
      2016-04-04
    • Data Source
      KAKENHI-PROJECT-26430116
  • [Presentation] テロメア構成タンパク質修飾とエピゲノム異常の関連性 -DNA損傷に対するクロマチン応答からの解析-2016

    • Author(s)
      渡邉すぎ子
    • Organizer
      第47回アステラス病態代謝研究会研究報告会
    • Place of Presentation
      東京都千代田区
    • Year and Date
      2016-10-15
    • Data Source
      KAKENHI-PROJECT-26430116
  • [Presentation] The Global-COE2008

    • Author(s)
      Sugiko Watanabe, Shin-ichi Akaboshi, Yuko Hino, and Mitsuyoshi Nakao
    • Organizer
      International Summer Retreat
    • Place of Presentation
      阿蘇
    • Year and Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-19790945
  • [Presentation] クロマチン因子による遺伝子・細胞制御機構2008

    • Author(s)
      中尾光善、石原宏、三代剛、日野信次朗、渡邉すぎ子、斉藤典子
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19790945
  • 1.  佐伯 浩司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  北尾 洋之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  沖 英次
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  原 英二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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